#=GF ID BDV_G
#=GF AC PF06208.15
#=GF DE Borna disease virus G protein
#=GF AU Moxon SJ;0000-0003-4644-1816
#=GF SE Pfam-B_10516 (release 9.0)
#=GF GA 25.00 25.00;
#=GF TC 143.20 142.90;
#=GF NC 21.60 21.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Family
#=GF WK Borna_disease_virus
#=GF RN [1]
#=GF RM 12163584
#=GF RT Enhanced neurovirulence of borna disease virus variants
#=GF RT associated with nucleotide changes in the glycoprotein and L
#=GF RT polymerase genes.
#=GF RA Nishino Y, Kobasa D, Rubin SA, Pletnikov MV, Carbone KM;
#=GF RL J Virol 2002;76:8650-8658.
#=GF RN [2]
#=GF RM 8985354
#=GF RT Biochemical and functional analysis of the Borna disease virus G
#=GF RT protein.
#=GF RA Schneider PA, Hatalski CG, Lewis AJ, Lipkin WI;
#=GF RL J Virol 1997;71:331-336.
#=GF RN [3]
#=GF RM 11435588
#=GF RT N-terminal domain of Borna disease virus G (p56) protein is
#=GF RT sufficient for virus receptor recognition and cell entry.
#=GF RA Perez M, Watanabe M, Whitt MA, de la Torre JC;
#=GF RL J Virol 2001;75:7078-7085.
#=GF DR INTERPRO; IPR009344;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family consists of Borna disease virus G glycoprotein
#=GF CC sequences. Borna disease virus (BDV) infection produces a
#=GF CC variety of clinical diseases, from behavioural illnesses to
#=GF CC classical fatal encephalitis [1]. G protein is important for
#=GF CC viral entry into the host cell [2,3].
#=GF SQ 6
#=GS VGLG_BDVV/1-503 AC P52638.1
#=GS A0A2P1GNX3_9MONO/4-484 AC A0A2P1GNX3.1
#=GS A0A2K8MTZ2_9MONO/34-523 AC A0A2K8MTZ2.1
#=GS G8FRY9_9MONO/1-500 AC G8FRY9.1
#=GS A0A077EMR3_9MONO/1-499 AC A0A077EMR3.1
#=GS A0A2K8MNE3_9MONO/35-522 AC A0A2K8MNE3.1
VGLG_BDVV/1-503 ......................MQPSMSFLIGFGTLVLVLSARTFDLQGLSCNTDSTPGLIDLEIRRLCHT..PT.E.N..VISCEVSYLNHTTISLPAVHTSCLKYHCKTYWGFFGSYSADR.IINRYTGTVKGC.LNNSAPEDPFECNWF.........YCCSAITTEICRCS.ITNVTVAVQTFPPFMYCSFADCSTVSQQELES.....GKAMLSDGSTLTYTPYILQSEVVNKT.LNG.TILCNSSSKIVSFDEFRRSYSLTNG.SYQSSSINVTCANYTSSCRPRLKRRRRDTQQIEYLVHKLRPTLKDAWEDCEILQSLLLGVFGTGIASASQFLRSWLNHPDIIGYIVNGVGVVWQCHRVNVTFMAWNESTYYPPVDYNGR.KYFLND.EG.RLQTNTPEARPG..LKRVMWF.GRYFLGTVGSGVKPRRIRYNKT.SHDYHLEEFEASLNMTPQTSIASGHETDPINHAYGTQADLLPYTRSSNITSTDTGSGWVHIGLPSFAFLNPLGWLRDLLAWAAWLGGVLYLISLCVSLPASFARRRRLGRWQE.............
A0A2P1GNX3_9MONO/4-484 ............aplllllllp--------------------TITPFKTLRCDTSSSPSAIKYVPPKV-DL..GL.Q.N..-ATCTVKAKKRITEGMQVEIHACYKITTYTSWGVFQDCDAKEeITRQYPGCIVG-.--DEIPSDPCTAWWWrgngpdiwkLASQRYKTEVCICLpSVSATVAVSNHPPPIYCSFDDCSTCTVRDLAA.....GLCTLRSMKDIKFVPKVLEAEEQETD.ESG.VF--HFHTRHIELPTFHSSYPLTADlKYSDANIKIECKL---VQRPR-RRKRDDVQQ--YVFDALAPHLAESKMTSWTISTLQDTILSQPLIDYTKYVQAILKRNDIVGTVNSGLVLYWSCDQVNADFLPWTNDTFYPPVTVNGSlQYLHPY.TG.ILFSSSPPAPHG..LYSLIYVdTKHYLGSVGSGTTPHTISTTHVlSSAYENVELDAL-----QDFRLGSHYIDPTSVAIGPLQDPLAAAHESSKRLLDAAA-LHSVGLGYVYQYDPMYLIKDLLVKVATIGGVMYFC---------------------ycmficfkylyhf
A0A2K8MTZ2_9MONO/34-523 .srlllyltfilicltipgtts-------------------ECNITTNGLHCNLTSTPTRISLNWTFPCDD..FN.QdNhqPARCNITLKTHDPTPLHAKAEKCYIYTCTTSFGFWGVYSESR.EVTRTLH-RNGCeFLDEIPEDPYTCNYW.........WCKYNVKTERCLCL.TENITVVA-LPNGHLYCSFEDCSMLSAQLKIQytptlTKVLILDNVTHTNATYANQPAT---I.ING.T--------RVMIHSLHKEYTIVNY.TLNDTSIDGQCEAASS------TRRRRDASQ-GYTIDSIGHLLYPGFEACRLLRTLLPAIALQPLLDHTLLLQAWFKNDSIAGRIVSDTALVWTCERVDCQLKNLSSTSLYFPVQCNDK.NFSLNP.WTnVLYSDGPDVGPGryLALKIAN.GSHITGVTGSGICPQVIEEPSM.TT----GIFSFTIPDLHEDLIQSVHILDPVFYALGMRRDFSATLHSSTNHETNTSETLWHIGLPSFSFLNPLGWIRDLTSWAAWLGGILYLVTIVIFLIRTLTRRVKYGR---.............
G8FRY9_9MONO/1-500 ..............mlhstysr--------FVFGTLVLGLWVQTYAIPALKCNTESTPSLIDLEIRRMCHN..KT.E.N..VVSCSVSYRNHTFAELNVTHVSCYKYHCKTYWGFFGSYSTDK.LISRFTGDSSQC.INGS-VEDPFVCNWY.........YCCSAIVNDVCRCS.ISNAQVSVKSFPPFMYCSFADCSTVNEKDLSN.....GNATLSDGSLLLFDPYNLTHDVVNGT.FNG.TIYCNGSSKVVSFDAFRRSYGLKNC.TYTDQSLNITCENCSSHCPHR--RRRRDLSEVTYLAHKLRPMLADAWEDCEILQSLILGSFGSGMSGASQFLREWLNHTDIVGYIVNGIGVIWQCQRVNVSFLPWNESTYYPPVDSNGT.RLYLND.ES.RLQTGSPEAIPG..LKRVMWY.GRMYLGTVNSGQRPKRVKYNRS.SHDYHLDEFDWSFNFTPIIALATGHETNPINHAFGTQSNLLPYAKSSNLTSTDTGSGWVHIGLPSFAFLNPMGWLRDIFSWAAWLGGILYLVQLAMSFPVLIARRRRLGRWSE.............
A0A077EMR3_9MONO/1-499 ......................MLPSMCILIGSGMLELVHLVQTSELQALNCDTRSSPALIDLEIRRLCHK..TT.E.N..VVSCEVSYQNHTVEEVKATLVSCYSYRCTTYWGFFGSYSADK.MTFRYTGNATTC.-NNQTVEEPYICNWY.........YCCSKAVNTICRCT.NNNVTVVIKSAPPYMYCSFGDCSTVTKREIER.....GLAKLSDGSLLYFNSTIIPPDIVNTS.ING.SVLCNNKSKLVSFDKFRRSYPLRKW.KYNSQSINITCSNDSNICP--AKRRKRDLSQVSYALHKIRPILADAWEDCEIMQSLILGMTGSNLFSSSQFLRKWLNRTDIIGYVVGGLGVIWQCSRVNVSFLSWNESTYFPPVSYMDK.IMYLND.ED.RLQDSTPEAKPG..LKRLLLH.GSYFLGTVGSGLKPKLVSYDRS.THDYHLDEFDAIFNLTPEVDLISGHETNPINHAFGTQSGLLPYTRSTNLTSTDTGSGWVHIGLPSFTFLNPLGWVRDILSWAAWIGGILYLITLCISLPALINRKRRLGRW--s............
A0A2K8MNE3_9MONO/35-522 qpllpyiliylvvpgmtlgcni-----------------------STTGLICNLTSTPTRIALNWTFPCDEanPDdQ.Q..PAECNITLMTHDPTPLHAKAEKCYVYVCTTSFGFWGVYSESR.EITRTLHRDECN.FVEEIPEDPYQCDYW.........WCQYNVKTEKCLCI.TENVTVV-GLPNGHLYCSFEDCSTLSS-----.....G-TKLQHTPTLTKILILNNTSHENVTyLNQpATIINS--TRVMIHSLHKEYTIYNG.TINATDLSGVCSE-----KTQIKRRKRDAGQ-GYTVDSIGHLLYPGFEACRLLRTLLPAIALQPLLDHTPLIQAWFNNDSLAGKVVSDTALIWTCKKVSCDLQNLSTNSLYFPVSCNKH.NFSLNPwTS.VLYSDGPNVGPGryLALKLSN.GSHVIGVTGSGICPQVIKEPSM.TT----GIFSFTIPDLHEELIQSAHVLDPVFYALGMNKDFSTTLHSSSNHETNVSESLWHIGLPSFSFINPLGWIRDLTSWAAWLGGILYLATLIVFLVRTLTRKIKYGR---.............
#=GC seq_cons ..............hhh.hh......................pshshpuLpCNTsSTPohIcLphp+hCcp..ss.p.N..ssoCsVohpsHsspsLpAptpuCYpYpCpT.WGFFGsYSsc+.hlsRasGssssC.hssphPEDPapCNWa.........aCspslpTElChCh.ssNlTVslpshPPahYCSFsDCSTlopp-ltp.....GhspLpDsssLpasshllps-h.Nso.lNG.ohhhNspo+hVphcsF++SYsLpNs.oYsssSIslsCps.os.p..p.+RRRRDsuQ.sYslcpltPhLt-uaEsCclLpoLl.ulhupsLhstopaLpuWLN+sDIlGhlVuGlullWpCcRVNssFhsWspoTaYPPVssNs+.pahLNs.pu.hL.osoP-AtPG..Ltpllhh.GpaaLGoVGSGlpP+hIchs+s.opsYc.sEF-hohs.h.pshltSuH.hDPlsaAhGsppDhLshs+SSshppTDTuuuhhHIGLPSFuFLNPLGWlRDLhSWAAWLGGILYLloLsl.LsthlsR+h+hGR................
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