#=GF ID   BLYB
#=GF AC   PF05289.15
#=GF DE   Borrelia hemolysin accessory protein
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_7729 (release 7.7)
#=GF GA   25.00 25.00;
#=GF TC   25.30 34.40;
#=GF NC   24.40 22.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11073925
#=GF RT   Characterization of Borrelia burgdorferi BlyA and BlyB proteins:
#=GF RT   a prophage-encoded holin-like system. 
#=GF RA   Damman CJ, Eggers CH, Samuels DS, Oliver DB; 
#=GF RL   J Bacteriol 2000;182:6791-6797.
#=GF RN   [2]
#=GF RM   8655511
#=GF RT   Borrelia burgdorferi supercoiled plasmids encode multicopy
#=GF RT   tandem open reading frames and a lipoprotein gene family. 
#=GF RA   Porcella SF, Popova TG, Akins DR, Li M, Radolf JD, Norgard MV; 
#=GF RL   J Bacteriol 1996;178:3293-3307.
#=GF DR   INTERPRO; IPR007953;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several borrelia hemolysin accessory
#=GF CC   proteins (BLYB). BLYB was thought to be an accessory protein,
#=GF CC   which was proposed to comprise a hemolysis system but it is now
#=GF CC   thought that BlyA and BlyB function instead as a
#=GF CC   prophage-encoded holin or holin-like system [1].
#=GF SQ   17
#=GS W6TKD5_9SPIR/2-114  AC W6TKD5.1
#=GS O50907_BORBU/3-124  AC O50907.1
#=GS Q7DFC1_BORBU/4-114  AC Q7DFC1.1
#=GS W6TG88_9SPIR/1-59   AC W6TG88.1
#=GS Q9S0C0_BORBU/4-114  AC Q9S0C0.1
#=GS Q9R2P8_BORBU/4-114  AC Q9R2P8.1
#=GS H7C7M4_BORBU/2-111  AC H7C7M4.1
#=GS W6TKL4_9SPIR/2-114  AC W6TKL4.1
#=GS W6TGG4_9SPIR/3-122  AC W6TGG4.1
#=GS H7C7Q0_BORBU/2-111  AC H7C7Q0.1
#=GS Q9S086_BORBU/4-114  AC Q9S086.1
#=GS W6TW52_9SPIR/2-114  AC W6TW52.1
#=GS W6TF54_9SPIR/1-65   AC W6TF54.1
#=GS H7C7Q4_BORBU/2-111  AC H7C7Q4.1
#=GS W6TGB3_9SPIR/2-114  AC W6TGB3.1
#=GS W6TFV4_9SPIR/4-104  AC W6TFV4.1
#=GS Q9S085_BORBU/2-111  AC Q9S085.1
W6TKD5_9SPIR/2-114             ..nls---TAKIGIDILNKFTE.LLQKNNNDKNtSTYTNIFLKVVN---YIFSLYEASINRMEQNEAIKLLSELEEIIRINIEIIknseDYYNQD.ENAKYISQLRNKRNKIMNSYIKILKE----------a.........
O50907_BORBU/3-124             .....NKMNINSGIDALNNLYD.FLKSSDSPTE.VKVEKGIYLGLNLYNLIMSIYKDKITTLEKEESLKILNEIKNVNNKITQLI....SSINDE.RDASIIEHLREERNELMSIKTQALQEQIKE------fpentsta..
Q7DFC1_BORBU/4-114             .....SKDNVELGLTSLSTLID.IFSKFEDEFD.EIAHKGFFLVYELYSHYKLIYTANMERLESALTPAINAALAPLNEKINQCI....DLVNSDeKNLKISNDLKFNQEG----------KPIYKERTNNA..........
W6TG88_9SPIR/1-59              ...le-----------------.----------.----------------YEHIYTKNMEILDNALTPQIKLAIEPIKTKIKKFI....EKVNSNsDNMQL-------------------------------pseitsyeke
Q9S0C0_BORBU/4-114             .....SKDNVELGLTSLSTLID.IFSKFEDEFD.EIAHKGFFLVYDLYSHYKLIYTANMERLESALTPAINAALAPLNEKINQCI....DLVNSDeKNLKISNDLKFNQEG----------KPIYKERINNA..........
Q9R2P8_BORBU/4-114             .....SKDNVELGLTSLSTLID.IFSKFEDEFD.EIAHKGFFLVYELYSHYKLIYTANMERLESALTPAINKALAPLNEKINQCI....DLVNSDeKNLKISNDLKFNQEG----------KPIYKERTNNA..........
H7C7M4_BORBU/2-111             .....QNNTIGLGLNLLSSLTN.I-AKTDTNID.HNYINTFSKVIDFF---YKTYISTLKSMETAESTKIFEEIKDILKYNIEII....EAISYD.KNKKIITSLKAKRNKIMKEYIKMLK------RSEN-a.........
W6TKL4_9SPIR/2-114             nlsta-----KININILNKFIE.LLQKN--NND.KNTSTYINIFLRVVNYILSLYEASINRMEQNEAIKLLSELEEIIRINIEIIknsdDYYNQD.ENAKYISQLRNKRNKIMNSYIKILKE----------a.........
W6TGG4_9SPIR/3-122             .....NKTNTELGLIVLKNLIE.FFVYSDTQDD.ELFQTGIKKVIDIYKYMNNIYTKSLQKMEMKESKQIVLELETILSKIAKLI....DAINTD.ADTTLIEDLRFERNNLIEIKTKLLQEELDKINSKNK..........
H7C7Q0_BORBU/2-111             .....QNNTIGLGLNLLSSLTN.I-AKTDTNID.HNYINTFSKVIDFF---YKTYISTLKSMETAESTKIFEEIQDILKYNIEII....EAISTD.KSKRIITSLKATRNKIMKEYIKILKR----------gena......
Q9S086_BORBU/4-114             .....SKDNVELGLTSLSTLID.IFSKFEDEFD.EIAHKGFFLVYELYSHYKLIYTANMERLESALTPAINAALAPLNAKINTVI....DLVNSNdKNLKISNDLKFNKDG----------KPIYKERANNA..........
W6TW52_9SPIR/2-114             ..nls---TAKIGIDILNKFTE.LLQKNNHDKNtSTYTNIFLKVVN---YIFSLYEASINRMEQNEAIKLLSELEEIIRINIEIIknseEYYNQD.ENAKYISQLRSKRNKIMNSYIKILKE----------a.........
W6TF54_9SPIR/1-65              .....-----------------.----------.-----------------------SINRMEQNEAIKLLSELEEIIRINIEIIknseDYYNQD.ENAKYISQLRNKRNKIMNSYIKILKE----------a.........
H7C7Q4_BORBU/2-111             .....QNNTIGLGLNLLSSLTN.I-AKTDTNID.HNYINTFSKVIDFF---YKTYISTLKSMETAESTKIFEEIQDILKYNIEII....EAISTD.KSKRIITSLKSTRNKIMKEYIKILKR----------gena......
W6TGB3_9SPIR/2-114             ..nls---TAKIGIDILNKFTE.LLQKNNHDKNtSTYTNIFLKVVN---YIFSLYEASINRMEQNEAIKLLSELEEIIRINIEIIknseDYYNQD.ENAKYISQLRNKRNKIMNSYIKILKE----------a.........
W6TFV4_9SPIR/4-104             ....s-KESLNASLNAISNLLDsLYNFKDATFD.RRDNQAFSLLHQFYLEYEHIYTKNMEILDNALTPQIKLAIEPIKTKIKKFI....EKVNSNsDNMQL-------------------------------pseitsyeke
Q9S085_BORBU/2-111             .....QKNTIELGLNLLSSLTN.I-AKTDTNID.HNYINTFSKVIDFF---YKTYISTLKSMETAESTKIFEEIKDILKYNIEII....EAISYD.KNKKIITSLKAKRNKIMKEYIKMLK------RSEN-a.........
#=GC seq_cons                  ......p.shplGlshLssLh-.lhtKp-sphD.c.hppsF.hVhpha..hhplYpuslpphEpsEohpIhpElcsIhch.hclI....-hlNpD.cNtKlIspL+.pRNplhp.hhphLpc..........s.........
//