#=GF ID   BTV_NS2
#=GF AC   PF04514.16
#=GF DE   Bluetongue virus non-structural protein NS2
#=GF AU   Kerrison ND;0000-0002-1471-953X
#=GF SE   DOMO:DM04350;
#=GF GA   25.00 25.00;
#=GF TC   44.80 37.20;
#=GF NC   20.90 19.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11752140
#=GF RT   Localization of the single-stranded RNA-binding domains of
#=GF RT   bluetongue virus nonstructural protein NS2. 
#=GF RA   Fillmore GC, Lin H, Li JK; 
#=GF RL   J Virol 2002;76:499-506.
#=GF RN   [2]
#=GF RM   11162836
#=GF RT   Multimers of the bluetongue virus nonstructural protein, NS2,
#=GF RT   possess nucleotidyl phosphatase activity: similarities between
#=GF RT   NS2 and rotavirus NSP2. 
#=GF RA   Taraporewala ZF, Chen D, Patton JT; 
#=GF RL   Virology 2001;280:221-231.
#=GF DR   INTERPRO; IPR007602;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family includes NS2 proteins from other members of the
#=GF CC   Orbivirus genus.  NS2 is a non-specific single-stranded
#=GF CC   RNA-binding protein that forms large homomultimers and
#=GF CC   accumulates in viral inclusion bodies of infected cells. Three
#=GF CC   RNA binding regions have been identified in Bluetongue virus
#=GF CC   serotype 17 (Swiss:P33473) at residues 2-11, 153-166 and 274-286
#=GF CC   [1]. NS2 multimers also possess nucleotidyl phosphatase activity
#=GF CC   [2]. The precise function of NS2 is not known, but it may be
#=GF CC   involved in the transport and condensation of viral mRNAs [1].
#=GF SQ   34
#=GS A0A0N9LU28_AHSV7/3-358   AC A0A0N9LU28.1
#=GS E1AA96_9VIRU/9-199       AC E1AA96.1
#=GS A0A0H4M5A6_9VIRU/11-196  AC A0A0H4M5A6.1
#=GS W5QLZ1_9VIRU/220-341     AC W5QLZ1.1
#=GS A0A077JI50_9VIRU/6-248   AC A0A077JI50.1
#=GS A0A097I4F0_9VIRU/1-364   AC A0A097I4F0.1
#=GS A0A1V0CK00_9VIRU/1-349   AC A0A1V0CK00.1
#=GS V9SED0_9VIRU/1-368       AC V9SED0.1
#=GS Q2YH50_9VIRU/30-227      AC Q2YH50.1
#=GS W5QLW8_9VIRU/211-335     AC W5QLW8.1
#=GS I6ZV95_9VIRU/1-349       AC I6ZV95.1
#=GS A0A0H4M3U8_9VIRU/5-205   AC A0A0H4M3U8.1
#=GS Q2Q1D6_9VIRU/19-222      AC Q2Q1D6.1
#=GS W5QLW8_9VIRU/1-188       AC W5QLW8.1
#=GS M4MJR4_9VIRU/11-197      AC M4MJR4.1
#=GS VNS2_BTV10/1-349         AC P23065.1
#=GS A0A0K1RIB7_9VIRU/1-349   AC A0A0K1RIB7.1
#=GS S6C8V4_9VIRU/5-197       AC S6C8V4.1
#=GS A0A173G2W8_9VIRU/8-366   AC A0A173G2W8.1
#=GS A0A109RY70_9VIRU/1-325   AC A0A109RY70.1
#=GS U5YJB2_9VIRU/208-308     AC U5YJB2.1
#=GS A0A0H4M5F0_9VIRU/2-192   AC A0A0H4M5F0.1
#=GS W5QLZ1_9VIRU/4-192       AC W5QLZ1.1
#=GS H9ZXS8_9VIRU/1-365       AC H9ZXS8.1
#=GS A0A0N7D0H5_AHSV2/3-358   AC A0A0N7D0H5.1
#=GS A0A0B5GDD0_9VIRU/3-358   AC A0A0B5GDD0.1
#=GS U3RAB0_9VIRU/1-334       AC U3RAB0.1
#=GS U5YJB2_9VIRU/1-210       AC U5YJB2.1
#=GS H9ZXR9_9VIRU/1-346       AC H9ZXR9.1
#=GS A0A0K1TPJ8_9VIRU/1-357   AC A0A0K1TPJ8.1
#=GS A0A346RV21_9VIRU/13-198  AC A0A346RV21.1
#=GS M1GUF7_9VIRU/1-217       AC M1GUF7.1
#=GS B4ERJ3_9VIRU/1-349       AC B4ERJ3.1
#=GS U5NGK0_9VIRU/11-233      AC U5NGK0.1
A0A0N9LU28_AHSV7/3-358              ...........................ev--RK.QQQFTRSVCVL.D.LGQKTYCGKVVRAVNGVYYTIKIGRTVQCGVTPTPIPKSYVLEIRECGAYRIQDGTDVLSLMITESGIEVTQNRWEEWSFEALTPV..PMAVAVNVGRGSFDTEIKYVRGSGAVPPYTK.N.G.M.D.RRAMPSLPGI..T...TL..DV...G...VRDLRLKMKE...NRE.AE....R.E.K..M....E....RALSGglDM..GScRMYgggrnDVREI........TLDEA.GPSRTPR.KLSV-Q......SNESR.....SDDVAR..RHAEL.-.-.VEM..ERLRM.MK......NEPVRTESMWC......QSDS.....DD.Q.....SDEDHEvgS.TEP...E.NYITEEYTRRLNE-VKTKySKELSSLAMRVPKNEGNCGKPIFSKKCKWENVPIYNYDEASGNYRFVSVGSATHYHCCANDLSYMI...............................................................
E1AA96_9VIRU/9-199                  .....mirkpftrtivlkstgkddyvakm----.-----------.-.----------CNALGCEYLVVRHGLGMHVAGSNTPTHGCMLLLIPGAGSFRLIDRDQSTFVVVSSDGLEVQQDRWPGMRFEAVDMF..PRCCRIVVGDVAADSEIRFGSASGTVPPYTAgE.S.M.E.AQDEISLPGL..D...FSvpDS...D...LREYREKLRE...EKE.ER....A.A.A..I....L....SA---..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------lrttqqsrtlgrlhg................................................
A0A0H4M5A6_9VIRU/11-196             irrpflrtisihstgtddyvsktchvmkg----.-----------.-.----------------SYLIVKQGMGSQQVVSDTPATGGMVLVIPGPGSYRLLDRDQSTFIIVDVNGIEVMPDRWPGFCFETVDMS..AHSATIDVGSEEVPGIVSYGRAAGTIPPYTP.D.G.N.G.PTNTITLPGIkfV...KS..DE...P...MRELRVRLKE...ERE.EH....A.T.K..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------itravralgasraagr...............................................
W5QLZ1_9VIRU/220-341                asrelddwgfdmqpktsgdwgaktpipev----.-----------.-.--------------------------------------------------------------------------------------..-------------------------------.-.-.-.-.----------..-...--..--...-...----------...---.--....-.-.-..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....---ESD..EgEMN...D.THITTAFISKCSEAAKKH.STTFSGLSARVPAASGKFDEVILVKKSAWGDVPLFRIDEATRKFEFMAIGTSTQVLCVKDDLSYM-l..............................................................
A0A077JI50_9VIRU/6-248              ....................hqkserrqm----.---FTRTFAFY.S.KDRNNYVGISCAAQGKNYLVVKIGQTTQMCFTDSPVSRGAIIDVRKQCSIRVQDRDQSTFFVISNCSIEWALDRWPRMVFETVDVH..TKFGHLIINEKEVETEFKCGVAHGIVAPYTE.E.A.D.QvGEGEIELPGVkfI...KI..EG...S...LREERERLKEmrdERE.ET....L.T.V..A....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------lkasgstraqgrihglrfdkvielekssdvvpqgrafkrgsssgssieqdveqfglqnmvqrg
A0A097I4F0_9VIRU/1-364              ....................megkktnvp----.-RLFTKRVYVL.D.TRKSTICGRISQLAGLPYCKIESGRVVSVTACAQPSDRGYVLEIEGKGAYRIVDGQDTISLMIDDYGVSMTTGRWEEYAFEMVSVR..PHVMKVKEDRVFKNIEIKHGRGCAAVPPYMR.V.D.R.E.QNSELRLPGT..E...RS..DM...D...VSTYRQKRRE...ERE.GMdrntQ.R.L..Q....P....AHMRS..EEmdRS.SWS.....EQVNAsk....aqKYDEE.FNKFQES.VRQIEL......EDEY-.....PAGQQD..DDNDD.N.F.GLGlvKDEDN.TS......QKKGGEEREKK......ASQQ.....DD.F.....GLDFEE..E.CAK...F.NYLTDTYSELVGKIVAKN.LKQLGGKSMIFPQLGDRYTEKLVVLTKECNNVPLYNIDEIAKEYRFAAIGTCKRIVMVAKGNS---fta............................................................
A0A1V0CK00_9VIRU/1-349              .............................MEQK.QRRFTKNIFVL.D.ANAKTLCGAIAKLSSLPYCQIKIGRVIAFKPVKNPEPKGYVLNVPGPGAYRIQDGQDIISLMLTPHGVEATTERWEEWKFEGVSVT..PMATRVQHNGVMVDAEIKYCKGMGIVQPYMR.N.D.F.D.RNEMPDLPGV..M...RS..NY...D...VRELRQKIKN...ERE.SA....P.R.L..Q....V....QSVAP..RE..ES.RWM.....DDDEA........KVDEE.AKEMIPG.TSRLEK......LREAR.....SNVFKE..VEAGI.N.W.NLD..EKDEE.DR......DEREDEEQAKT......LSDD.....DE.Q.....GEDTSD..D.EHP...K.THITKEYIEKVAKQIKLK.DERFMSLSSAMPQASGGFDRMIVTKKLKWQNVPLYCFDESSKRYELQCVGACERVAFVSKDMSLII...............................................................
V9SED0_9VIRU/1-368                  .............................MEQK.QKRFTKNVFVL.D.QKRKTICGQIAARQSLPYCQIKIGRNFALRAVATPEPKGYVLEICDVGAYRIQDGNDVISLMISVDGVEGTQERWEEWKFETISCV..PMATILNINGALVDAEIKVSKGMGIVPPYTR.N.D.F.D.RRELPELPGV..Q...RS..KY...D...IRELRQKIRE...ERE.KG....A.V.E..Q....P....HKPTF..KT..E-.RWH.....EQPDS........DEDQNpASGVVNDwTCETQKrdqeaeRREAL.....EIRLAE..QRQRIeA.F.KFD..SERRR.ED......LERSQE-QFRTqeverkKSDMgeviiEE.D.....DEDSEE..E.EGA...RaSYITSAYIERISKIRKIK.DERLSMLASMMPQQSGEYTTILFIKKQKWDNVPLYLIDEMQKKYELQSVGSCERVAFVSKGTNLII...............................................................
Q2YH50_9VIRU/30-227                 ........................fergp----.--RIATRTFVF.YcTTSTTSVGKIAKAFGTQYLAVKVGTTTHFEGVNFPIPRCTLITVLGPCAIKVIDRDVTCSFMITETGLEASMNRWAKYKFETVETS..SRFCKINIGGKMIEESIRVGKATGLVMPYTE.E.D.MmQ.QEEMDDLPGV..E...FI..NL...DsdqVQEQREKLKI...GRE.IT....-.-.-..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------rdmigsalrecgasrsegrlfglrsd.....................................
W5QLW8_9VIRU/211-335                ............aqlkldvpnwdqptdsd----.-----------.-.--------------------------------------------------------------------------------------..-------------------------------.-.-.-.-.----------..-...--..--...-...----------...---.--....-.-.-..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......DEDEESKRVTT......QSNA.....DT.E.....E-----..Q.VTF...E.DCITDQYFSKTGEFAKKY.PEMLAGLSAKMPSETGRFTKILTTRKAQWNNVPLFELDPNGFTYHFSKLGNSTRIFCVQRDLSYM-v..............................................................
I6ZV95_9VIRU/1-349                  .............................MEQK.QRRFTKNIFVL.D.ANAKTLCGAIAKLSSQPYCQIKIGRVIAFKPVKNPEPKGYVLNVPGPGAYRIQDGQDIISLMLTPHGVEATTERWEEWKFEGVSVT..PMATRVQHNGVMVDAEIKYCKGMGIVQPYMR.N.D.F.D.RNEMPDLPGV..M...RS..NY...D...VRELRQKIKN...ERE.SA....P.R.L..Q....V....QSVAP..RE..ES.RWM.....DDDEA........KVDEE.AKEMIPG.TSRLEK......LREAR.....SNVFKE..VEAGI.N.W.NLD..EKDDE.DR......DEQEDEGRVKT......LSDD.....DE.Q.....GEDASD..D.EHP...K.THITKEYIEKVAKQIKLK.DERFMSLSSAMPQASGGFDRMIVTKKLKWQNVPLYCFDESSKRYELQCVGACERVAFVSKDMSLII...............................................................
A0A0H4M3U8_9VIRU/5-205              ....................qpkmirrpy----.----TK-VLAI.K.SSGTDFVAQMCKALSREYLVVKHGMNTQIVGADAPPPKAMLLLIPHEGAFRLLDRDQSFFVMVDRDGIEVTQDRWPGMRFETIDLM..TRGVELMIAGQPITTEVRYGVAAGLVPPYVP.D.E.SrS.KEDEPEFPGVkfI...EV..EG...G...MREFRERLKE...DAE.I-....-.-.-..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------rasaltsalheaqstrclgrlmgmrnadlgr................................
Q2Q1D6_9VIRU/19-222                 .........................adra----.NRVLTRTFSLY.S.LNNNNFIGKVTKCMNAQYLAVKVGITTHFEAVNVPPPRSTVITVSNPCAFKVQDRETTTHFMISESGLEACLGRWSKYKFESVDTT..SRFCKMSIGGQTVEETIRVGKCLGIVQPYTE.E.EmM.D.IGEGIELPGI..S...FV..NLqseE...VAEFRSKLRV...ERD.MK....R.D.L..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------igvalkesgaarsegrlfglkleataklq..................................
W5QLW8_9VIRU/1-188                  .........................maqe---V.KRKFTRTVCIY.D.PQNRTFCGRSAAMVCNSYYTIKMGRTTQCGVSPVPVPKSYVLEIPDVGSYRILDGQDSISVIVTETGVEATSERWEEWKFEGVNCV..PMVVQTEIGKGLIDMEIKFSKGMGLVKPYVK.N.E.V.S.RTEIPRLPGA..S...VI..DT...P...IRDYRQLLKD...QRD.E-....-.-.-..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------rraaldaiacdicptlsrml...........................................
M4MJR4_9VIRU/11-197                 ikkpftrvivlksdgrddfvakmcavlgc----.-----------.-.----------------EYVVVRHGLGTQIAGSDTPAHGCLLLTIPGPGSFRMIDRDQSTFLVVSGDGLEVQQDRWTGMRFEAVDMY..PRACRIRYGEKENDSEIRFGRASGTVPPYTP.D.G.VsE.EQEEVALPGI..Sf.hTP..EE...D...YKEYRERLRE...ERD.LR....-.-.-..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------sanilealrtthqsrtlgr............................................
VNS2_BTV10/1-349                    .............................MEQK.QRRFTKNIFVL.D.VTAKTLCGAIAKLSSQPYCQIKIGRVVAFKPVKNPEPKGYVLNVPGPGAYRIQDGQDIISLMLTPHGVEATTERWEEWKFEGVSVT..PMATRVQYNGVMVDAEIKYCKGMGIVQPYMR.N.D.F.D.RNEMPDLPGV..M...RS..NY...D...IRELRQKIKN...ERE.SA....P.R.L..Q....V....HSVAP..RE..ES.RWM.....DDDEA........KVDDE.AKEIVPG.TSGLEK......LREAR.....SNVFKE..VEAVI.N.W.NLD..ERDEG.DR......DERGDEEQVKT......LSDD.....DD.Q.....GEDASD..D.EHP...K.THITKEYIEKVAKQIKLK.DERFMSLSSAMPQASGGFDRMIVTKKLKWQNVPLYCFDESLKRYELQCVGACERVAFVSKDMSLII...............................................................
A0A0K1RIB7_9VIRU/1-349              .............................MEQK.QRKFTKNIFVL.D.VNAKTLCGVIAKQSSQPYCQIKIGRVIAFKPVKNPEPKGYVLNVPGPGAYRIQDGQDIISIMLTPSGVEATTERWEEWKFEGVSVT..PMATRVQHNGVMVDAEIKYCKGMGIVQPYMR.N.D.F.D.RNEMPDLPGV..M...RS..NY...D...IRELRQKIKN...ERE.MA....P.R.P..Q....I....QSAAP..RE..ES.RWM.....DEDEA........RVNEE.IKEAASS.VGRLER......LREAR.....TNMFRE..VEAGV.S.W.NLD..HQSEE.EA......DGDEDGDHANH......QADE.....DE.Q.....GEDASD..D.EHP...K.THITKEYIEKVAKQVKLK.DERFMSLSSAMPQASGGFDRMIVTKKLKWQNVPLYCFDESTKRYELQCVGACERVAFVSKDMSLII...............................................................
S6C8V4_9VIRU/5-197                  ...........................km--EK.PRRFTRTVCIL.D.RTENTYAGKVSRMMKNPYFIIKAGRSVVTGTAPFPPPRSTVIEVSDECAVAIQDGTDVTYIQLTRETVELCVERWNEYKFETLNPT..SNVGRINIGGSDVLGEIKYAKAQSLIRPYTR.N.A.S.R.SSDMPNLPGL..T...PT..DI...D...VRTHRDEDRK...NREeGR....A.R.L..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------enalrganlgassrlfgvdaa..........................................
A0A173G2W8_9VIRU/8-366              ..........................vtr---E.RRRFPKTFLFW.S.DDESNFVGMMSKVTGKPYLAIRTGMTTQVSMMDYVVPRASLVEILSCGSYRIQDRDEATFFVISEHGIEVAPERWPKLLFETVDLQ..SRFCEINVGGDLVKTDVKYGRGHGTIAPYTE.EaD.S.S.TDSDIHLPGIsfY...RV..EG...D...VREERERLKN...ARE.ER....E.E.K..IltalI....EAGGT..RS..EG.RML.....G---L........KFDKI.ANLQISG.EHEKRK......PK-LK.....ASRKDE..SEKIK.E.WpDVD..SSDDD.PKigiqlgHERPKPKPARR......SSTD.....DT.A.....EPKEIQ..N.EQG...Q.AKDNWKKLATSIMKMKTI.KEDAAGLKVVEPAHTGVFDSIMTSVSFDSVCVPTFKVDSHAKEYSRTGYALSKRA-----------hivisgetlti....................................................
A0A109RY70_9VIRU/1-325              ..........................mgd----.RKRYTKTVCVY.D.PQNATFCSRGANA-GENYYQVKIGRTTQITRTNAPNPKAYVVEIQRPCSVRLLDGNDIISLIISEEGIEVTTERWEEWLFEALTPI..PMVISLHIKGQKTEAEIKYCKASGVIAPYTP.N.G.V.D.RRVTPQLPGI..T...FT..DV...S...VRDFRQKMRE...ERE.KE....KeR.T.pM....I....TPIKP..KS..EA.PMM.....GPSTS........QQYQK.EESIAVG.-----K......I----.....SDYVKK..VTL--.E.S.N-V..ERDSD.DE......DEHGSN-----......-SDS.....DF.D.....GEPK--..D.---...E.GYITQNYMNMI-ETVKMK.VPGVAGLTLKIPKAAGKTDGMIAAKKCKWISVPLFNIDKDGLSYDFVAVGDAN-------------gflclrdglsylv..................................................
U5YJB2_9VIRU/208-308                ....................vpseiphgs----.-----------.-.--------------------------------------------------------------------------------------..-------------------------------.-.-.-.-.----------..-...--..--...-...----------...---.--....-.-.-..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....--SEEE..E.EEG...G.EYLTGKYMKKVSTIVKNP.DPSVLGMAFGYPKTSGPFDRIIVEKECLWTGVPIYDVDQTDKSYRLVMIGEATKY-----------llavkgqnyf.....................................................
A0A0H4M5F0_9VIRU/2-192              .........................aesa---Q.KRTFTRTVVIY.S.KGEHDFVARMMKSMAFPYLLIKIGQSVQLLGCKVPPPRSWLVEIHKEGSYRLVDRESSVYLVVSADGVEVQQDRWPRLCFETVDLR..ARFCEMTVGSSELQSEIKFGVGKGYVAPYTE.EsD.T.G.NDQQIILPGIrlI...RI..SG...D...AREFREKLKE...ERD.TR....D.R.I..I....V....EGIR-..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------atggtrctar.....................................................
W5QLZ1_9VIRU/4-192                  ..........................eqv--QV.KRKFTRTICVL.D.PGAKTFCGKVAKLEGKTYFVIKIGRTTQVGVSNTPVPKCYVLDVAGPGSYRVQDGQDTVSVILSESGFEATGERWEEWRFEVLSAT..PIVARMAVGEDEFDAEIKYSKGLGSVPPYAK.N.E.A.D.RRMMPTLPGV..K...AL..DM...P...IRDFRQHARE...HRD.EV....-.R.A..Q....L....DRAAR..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------rldpsssrllg....................................................
H9ZXS8_9VIRU/1-365                  .............................MEQK.PRRFTKTICVY.D.PSGRTICGKVAKEKRDPYAIIKLGRVFSLKSADGPQPKSYVLEISRPGAYRIQDGQDTISLMIEENGVEGTTERWEEWKFETLNPM..PMATMIRHNGQMVDAELKYCKGMGMIEPYTK.N.D.F.D.RKEMPALPGV..E...QS..KY...E...VRELRQKIRE...ERE.AQ....A.KgLlpQ....P....RDMRV..RE..EE.QMQ.....RAQEVvrqektsyKWEDD.IDFDQPK.DTQVRK.....dFDEER.....H--RQE..QRAQR.R.N.EQN..ERDEElHR......KLEAFEQNILN......KAEK.....ME.QiveevSEESEE..E.EVV...E.SYITAEYIERMSKQQKTK.DERFMSYAQMMPQAQGDFDRILVTKKVKWDNVPLFIVNESRKAYELQAIGECVRVVFAVKGTNLLI...............................................................
A0A0N7D0H5_AHSV2/3-358              ...........................ev--RK.QQQFTRSVCVL.D.LGQKTYCGKVVRAVNGVYYTIKIGRTVQCGVTPTPIPKSYVLEIRECGAYRIQDGTDVLSLMITESGIEVTQNRWEEWSFEALTPV..PMAVAVNVGRGSFDTEIKYVRGSGAVPPYTK.N.G.M.D.RRAMPSLPGI..T...TL..DV...G...VRDLRLKMKE...NRE.AE....R.E.K..M....E....RALSGglDM..GScRMYgggrnDVREI........TLDEA.GPSRTPR.KLSV-Q......SNESR.....SDDVAR..RHAEL.-.-.VEM..ERLRM.MK......NEPVRTESMWC......QSDS.....DD.Q.....SDEDHEvgS.TEP...E.NYITEEYTRRLNE-VKTKySKELSSLAMRVPKNEGNCGKPIFSKKCKWENVPIYNYDEASGNYRFVSVGSATHYHCCANDLSYMI...............................................................
A0A0B5GDD0_9VIRU/3-358              ...........................ev--RK.QQQFTRSVCVL.D.LGEKTYCGKVVRAVNGVYYTIKIGRTVQCGVTPTPIPKSYVLEIRECGAYRIQDGTDVLSLMITESGIEVTQNRWEEWSFEALTPV..PMAVAVNVGRGSFDTEIKYVRGSGAVPPYTK.N.G.M.D.RRAMPSLPGI..T...TL..DV...G...VRDLRLKMKE...NRE.AE....R.E.K..M....E....RALSGglDM..GScRMYgggrnDVREI........TLDEA.GPSRTPR.KLSV-Q......SNESR.....SDDVAR..RHAEL.-.-.VEM..ERLRM.MK......NEPVRTESMWC......QSDS.....DD.Q.....SDEDHEvgS.TEP...E.NYITEEYTRRLNE-VKTKySKELSSLAMRVPKNEGNCGKPIFSKKCKWENVPIYNYDEASGNYRFVSVGSATHYHCCANDLSYMI...............................................................
U3RAB0_9VIRU/1-334                  ........................meqrt--QL.RRVFPKTVCVL.D.PKGETICGMIAKSQHKPYCLVRTGRVICLKAISQPPPKAYVLEVVKCGAYRLIDGQDQISIMLNKDCVEMTSERWEEWQYEMVSIK..PMVVSLQLEYGVVDAELKYGKGFGSVEPYKK.N.E.L.E.RGEVPTLPGV..Q...QS..AV...G...LRELRTKLKK...ERE.E-....-.K.V..Q....G....RSVEL..--..--.PTM.....----K........KVNVQ.AEQGFEW.SAVREK......V----.....VEMEEE..IKDWA.E.H.GSS..EEEIN.DK......QQTDDEEVVK-......-DDD.....DE.A.....TEEG--..L.VKV...D.SFITGDYVNYVSGMSKKK.DERLSGLSLSFPKIEGEFEKVLCIKKTEQTGFPVFEVDQATKTFRFRMIGKCDRVFVVKRSMSMV-y..............................................................
U5YJB2_9VIRU/1-210                  .............................MESKpKRVFTKTVCVL.D.AYGKTFCGNVAKLCNKPYCLIKIGRVVSIEAVDNPRPKSYILQIEQVGSYRIQDGQDNISLIITNQGVEATVERWEEWKFENLSPI..PMATMIMVADKRVDAEVKFVKGMGIIAPYTK.N.E.M.D.RRDVPDLPGV..M...PS..SM...G...VKELREKLRN...ERE.QG....K.V.R..E....S....EIVRP..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------avvnhvveqpkwedldtkiaavtdwnadvps................................
H9ZXR9_9VIRU/1-346                  .......................mesktv----.RRVFTKQVCIL.D.PGCTTICGKIAREAKCPYAQLKTGRVCGFQAVKSPPPKAYILEITRPGAYRIMDGQDQISMMIEEGGIEITTDRWEEWKYEVVTAM..PMTALVDTPKGKVDAELKYAKGAGLVPAYTK.N.E.F.D.RRELPSLPGV..G...IS..EI...S...VRDLRAKLKA...ERV.MD...nP.R.S..-....-....---EH..RD..DR.RKS.....TRDET........PVFDV.S-EMLK-.--KVEE......MRSEE.....RSWSDE..MEDEA.AgG.SVD.vQQDDG.AL......---WEDETAKD......VDDE.....SKvM.....LEDITE..E.EEPfnaT.NFITEAFVTNVSAYMKSG.DKRVVGLASSFPKSAGSFDSVVCVKKANWMNVPLFDVDVGKKGYGLRMIGDSAKLYIVKRGLSVM-v..............................................................
A0A0K1TPJ8_9VIRU/1-357              .............................MEHK.PKRFTKNVSVL.D.GSGTTICGIIAKSAHKPYCNISIGRNVSIKAVDNPPPKAYVLQIRQEGGYRIQDGQDTISLMITASGVEATVERWEEWQFEVLSAMpmPMAIMMQHNGEMVDAEIKYAKGMGVVAPYVK.N.DeV.D.RRELPKLPGL..S...ES..QY...D...VKTLRQKIKE...ERE.RG....V.T.E..I....R....SKIQP..LE.qET.KRM.....ESVE-........KSFAE.MKAIWAA.ESKADV......KEENVggtygTDFFKPfpIESTK.M.P.ELK..SLEQR.EQ......QKEKEVAQAQS......FSVD.....VE.S.....GSEEEV..-.EEP...-.NYITQEYVDKASKVVKGG.EKKIAGLAYVMPKSIGDFSKIIAVKKHKWSNVPLFTVDEKGLKYELQTIGECETVVYAARGLNLL-v..............................................................
A0A346RV21_9VIRU/13-198             ..............ektsrlpirtatfyc----.-----------.-.TTGNTFIGKVSKALGTTYVVVKVGMSTHIQGVNAPPPRSSVITISTPCAIKLVDREATVYFMISDNGIEARIGRWPRYKFETVDTS..ARFCKIQIGSEVVEESLRVGKAVGMVPPYTD.E.E.VaE.IGEDLDLPGV..S...FM..NVessN...VGEYRNKLRE...QRD.V-....-.-.-..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------rrdvigaalkemgaar...............................................
M1GUF7_9VIRU/1-217                  ......................medkrer----.PRVYTKTFLLY.S.QDEGNFVGKICRAMKAVYYAVKVGQTTHMCVTDDPVPQAFVISIGSEGAYRVIDRDESVYFMITGDGVEVATGRWPKYQFESVDVV..PRFCSITVKGQEVETELKVGRGVGNVKPYTE.LmA.I.K.TEGVCELPGI..K...FL..NIe.gD...VREARAKLKE...ERG.QR....D.E.I..I....LtalkESNAD..RG..IA.RFM.....G----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------lrndkvmllenvskievgsps..........................................
B4ERJ3_9VIRU/1-349                  .............................MEQK.QRKFTKNIFVL.D.VNAKTLCGVIAKQSSQPYCQIKIGRVIAFKPVKNPEPKGYVLNVPGPGAYRIQDGQDIISIMLTPSGVEATTERWEEWKFEGVSVT..PMATRVQHNGVMVDAEIKYCKGMGIVQPYMR.N.D.F.D.RNEMPDLPGV..M...RS..NY...D...IRELRQKIKN...ERE.MA....P.R.P..Q....I....QSAAP..RE..ES.RWM.....DEDEA........RVNEE.IKEAASS.VGRLER......LREAR.....TNMFRE..VEAGV.S.W.NLD..HQSEE.EA......DGDEDGDHANH......QADE.....DE.Q.....GEDASD..D.EHP...K.THITKEYIEKVAKQVKLK.DERFMSLSSAMPQASGGFDRMIVTKKLKWQNVPLYCFDESTKRYELQCVGACERVAFVSKDMSLII...............................................................
U5NGK0_9VIRU/11-233                 .................sgdrvtrtpirt----.--------FILyS.TTEDNFVGRICKTLHTQYLAVKLGVSTHIEGVNTPVPRSTVVTITGPCAFKVVDRETTCHFMISATGIETRIGRWAQYKFETVETR..SRFCKMEIGGQSVDEMLRLGRATGSVLPYTE.E.E.MmG.GDEDVDLPGV..KivsVE..NE...D...VPNLREKMKM...ERQ.TK....R.D.L..-....-....-----..--..--.---.....-----........-----.-------.------......-----.....------..-----.-.-.---..-----.--......-----------......----.....--.-.....------..-.---...-.------------------.------------------------------------------------------------------igmalkesgatrgegrlygarpetmaklqsvkklttriqgkqekldr................
#=GC seq_cons                       ...........................t.......phFT+slhlh.s..stpThsGtls+h.stsYhhlKlGpssphtssssP.P+uhVLpl.tsGuYRl.Dtp-slplhlotsGlEsst-RWpcapFEslssh..Phssplplsst.l-sElKas+uhGhV.PYsc.s.-.h.-.ppphspLPGl......h...sh...s...lR-hRpKl+p...ERE.tt......p.h..................................................................................................................................................................................................................................................................h..............................................................
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