#=GF ID Bacteriocin_IIc
#=GF AC PF10439.13
#=GF DE Bacteriocin class II with double-glycine leader peptide
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE Manual
#=GF GA 27.10 27.10;
#=GF TC 27.20 27.20;
#=GF NC 27.00 27.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF CL CL0400
#=GF RN [1]
#=GF RM 17074857
#=GF RT The blp bacteriocins of Streptococcus pneumoniae mediate
#=GF RT intraspecies competition both in vitro and in vivo.
#=GF RA Dawid S, Roche AM, Weiser JN;
#=GF RL Infect Immun. 2007;75:443-451.
#=GF RN [2]
#=GF RM 17298586
#=GF RT Diversity of enterococcal bacteriocins and their grouping in a
#=GF RT new classification scheme.
#=GF RA Franz CM, van Belkum MJ, Holzapfel WH, Abriouel H, Galvez A;
#=GF RL FEMS Microbiol Rev. 2007;31:293-310.
#=GF DR INTERPRO; IPR019493;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This is a family of bacteriocidal bacteriocins secreted by
#=GF CC Streptococcal species in order to kill off closely-related
#=GF CC competitor Gram-positives. The sequence includes the peptide
#=GF CC precursor, this being cleaved off proteolytically at the
#=GF CC double-glycine. The family does not carry the YGNGVXC motif
#=GF CC characteristic of pediocin-like Bacteriocins, Bacteriocin_II
#=GF CC Pfam:PF01721. The producer bacteria are protected from the
#=GF CC effects of their own bacteriocins by production of a specific
#=GF CC immunity protein which is co-transcribed with the genes encoding
#=GF CC the bacteriocins, eg family EntA_Immun Pfam:PF08951. The
#=GF CC bacteriocins are structurally more specific than their
#=GF CC immunity-protein counterparts. Typically, production of the
#=GF CC bacteriocin gene is from within an operon carrying up to 6 genes
#=GF CC including a typical two-component regulatory system (R and H), a
#=GF CC small peptide pheromone (C), and a dedicated ABC transporter (A
#=GF CC and -B) as well as an immunity protein [1]. The ABC transporter
#=GF CC is thought to recognise the N termini of both the pheromone and
#=GF CC the bacteriocins and to transport these peptides across the
#=GF CC cytoplasmic membrane, concurrent with cleavage at the conserved
#=GF CC double-glycine motif. Cleaved extracellular C can then bind to
#=GF CC the sensor kinase, H, resulting in activation of R and
#=GF CC up-regulation of the entire gene cluster via binding to
#=GF CC consensus sequences within each promoter [2]. It seems likely
#=GF CC that this whole regulon is carried on a transmissible plasmid
#=GF CC which is passed between closely related Firmicute species since
#=GF CC many clinical isolates from different Firmicutes can produce at
#=GF CC least two bacteriocins. and the same bacteriocins can be
#=GF CC produced by different species.
#=GF SQ 102
#=GS Q8DW08_STRMU/6-71 AC Q8DW08.1
#=GS G5JMJ7_STRCG/7-59 AC G5JMJ7.1
#=GS A0A139NHC3_9STRE/1-58 AC A0A139NHC3.1
#=GS A0A5J5FWL1_9BACL/1-70 AC A0A5J5FWL1.1
#=GS A0A1E5G4L8_9FIRM/1-55 AC A0A1E5G4L8.1
#=GS A5M6F3_STREE/6-68 AC A5M6F3.1
#=GS A0A1K1P8M8_9GAMM/1-66 AC A0A1K1P8M8.1
#=GS A0A4R3YLK4_9GAMM/1-73 AC A0A4R3YLK4.1
#=GS A0A553GSH8_9BACT/1-54 AC A0A553GSH8.1
#=GS L0KCR9_HALHC/1-56 AC L0KCR9.1
#=GS A0A4U1B4N5_9GAMM/1-58 AC A0A4U1B4N5.1
#=GS R2SSJ5_9ENTE/1-55 AC R2SSJ5.1
#=GS A0A1A9HNN2_9BURK/1-62 AC A0A1A9HNN2.1
#=GS A0A139WTX4_9CYAN/1-70 AC A0A139WTX4.1
#=GS D9SPP3_CLOC7/1-71 AC D9SPP3.1
#=GS A0A139NEU2_9STRE/3-63 AC A0A139NEU2.1
#=GS Q5M2W2_STRT2/6-65 AC Q5M2W2.1
#=GS Q8DSB5_STRMU/7-81 AC Q8DSB5.1
#=GS A0A347WMH6_9LACT/1-58 AC A0A347WMH6.1
#=GS B7GL22_ANOFW/1-86 AC B7GL22.1
#=GS A0A371QME9_9BACT/6-68 AC A0A371QME9.1
#=GS A0A2L0D506_9STRE/1-64 AC A0A2L0D506.1
#=GS A0A1I7JF40_9FIRM/1-74 AC A0A1I7JF40.1
#=GS A0A5C5TCW4_9STRE/1-50 AC A0A5C5TCW4.1
#=GS J0V0Y6_STREE/4-49 AC J0V0Y6.1
#=GS A0A3N2KW95_9BACT/2-68 AC A0A3N2KW95.1
#=GS A0A1I1FLD5_9LACO/3-67 AC A0A1I1FLD5.1
#=GS A0A7X6MYB5_9STRE/6-65 AC A0A7X6MYB5.1
#=GS B7GL23_ANOFW/1-65 AC B7GL23.1
#=GS A0A109RHX2_9LACT/5-63 AC A0A109RHX2.1
#=GS A0A6V7TKH7_9BILA/4-44 AC A0A6V7TKH7.1
#=GS A0A1M5QU89_9FIRM/1-76 AC A0A1M5QU89.1
#=GS A0A172Q637_9STRE/6-62 AC A0A172Q637.1
#=GS J1NZV6_STREE/1-61 AC J1NZV6.1
#=GS Q8DSB1_STRMU/10-94 AC Q8DSB1.1
#=GS A0A380KA75_9STRE/5-72 AC A0A380KA75.1
#=GS J1P4N6_STREE/6-65 AC J1P4N6.1
#=GS A5M6F0_STREE/6-63 AC A5M6F0.1
#=GS A0A4Y9HE79_9BACL/4-53 AC A0A4Y9HE79.1
#=GS T1ZF07_STRIT/6-72 AC T1ZF07.1
#=GS A0A437SU16_9LACO/11-81 AC A0A437SU16.1
#=GS W7CGP1_9LIST/1-77 AC W7CGP1.1
#=GS G5JPG8_STRCG/6-49 AC G5JPG8.1
#=GS Q1WQX8_LIGS1/1-65 AC Q1WQX8.1
#=GS A0A383U1V8_9FLAO/1-51 AC A0A383U1V8.1
#=GS I5BT60_9BACT/1-80 AC I5BT60.1
#=GS L0KBX3_HALHC/1-64 AC L0KBX3.1
#=GS Q9PCT5_XYLFA/1-72 AC Q9PCT5.1
#=GS A0A145WNP8_9GAMM/30-71 AC A0A145WNP8.1
#=GS A0A7W9SVB4_9BACT/30-93 AC A0A7W9SVB4.1
#=GS T1ZF76_STRIT/6-66 AC T1ZF76.1
#=GS A0A8J3CXR3_9BACT/1-58 AC A0A8J3CXR3.1
#=GS A0A1M5QU07_9FIRM/1-73 AC A0A1M5QU07.1
#=GS D9SR35_CLOC7/1-57 AC D9SR35.1
#=GS I0XAR7_9SPIR/66-123 AC I0XAR7.1
#=GS A0A4Q7PJR5_9FLAO/1-62 AC A0A4Q7PJR5.1
#=GS A0A4Q1SLZ3_9BACL/1-64 AC A0A4Q1SLZ3.1
#=GS A0A172Q9E3_9STRE/1-41 AC A0A172Q9E3.1
#=GS B2JC36_NOSP7/16-67 AC B2JC36.1
#=GS A0A6A0BAV4_9LACT/7-53 AC A0A6A0BAV4.1
#=GS A5CZV1_PELTS/2-58 AC A5CZV1.1
#=GS D9SR36_CLOC7/1-58 AC D9SR36.1
#=GS T1ZF04_STRIT/6-65 AC T1ZF04.1
#=GS Q8DWB6_STRMU/1-76 AC Q8DWB6.1
#=GS A5CZV3_PELTS/2-56 AC A5CZV3.1
#=GS I5BT61_9BACT/1-70 AC I5BT61.1
#=GS A0A4Y9HC61_9BACL/5-68 AC A0A4Y9HC61.1
#=GS D9SSI4_CLOC7/7-70 AC D9SSI4.1
#=GS A0A380KA66_9STRE/2-55 AC A0A380KA66.1
#=GS Q5FI73_LACAC/1-64 AC Q5FI73.1
#=GS A0A1H1YFL4_9BACL/5-73 AC A0A1H1YFL4.1
#=GS A0A4Q9XLL5_9ALTE/26-84 AC A0A4Q9XLL5.1
#=GS A0A4Y9F9Q7_9STRE/1-61 AC A0A4Y9F9Q7.1
#=GS B9DTX8_STRU0/1-88 AC B9DTX8.1
#=GS Q8DRN0_STRR6/6-65 AC Q8DRN0.1
#=GS A0A139NEK0_9STRE/1-72 AC A0A139NEK0.1
#=GS A0A7Y0HTM2_9BIFI/5-52 AC A0A7Y0HTM2.1
#=GS A0A4Y9FJR2_9STRE/8-70 AC A0A4Y9FJR2.1
#=GS Q9A139_STRP1/2-63 AC Q9A139.1
#=GS Q8DSA3_STRMU/1-62 AC Q8DSA3.1
#=GS Q1WQX7_LIGS1/2-62 AC Q1WQX7.1
#=GS M9L947_PAEPP/1-82 AC M9L947.1
#=GS G6ERX6_STRTR/6-68 AC G6ERX6.1
#=GS A0A7G9BI36_9SPHI/2-71 AC A0A7G9BI36.1
#=GS A0A2L0D508_9STRE/1-69 AC A0A2L0D508.1
#=GS A0A1G6X8W7_9GAMM/1-54 AC A0A1G6X8W7.1
#=GS J0VAC6_STREE/6-48 AC J0VAC6.1
#=GS F5IUS8_9BACT/1-57 AC F5IUS8.1
#=GS A0A172Q635_9STRE/1-59 AC A0A172Q635.1
#=GS Q8DS95_STRMU/6-71 AC Q8DS95.1
#=GS A0A172Q613_9STRE/6-66 AC A0A172Q613.1
#=GS H8KYJ8_FRAAD/1-71 AC H8KYJ8.1
#=GS Q8DWB7_STRMU/6-52 AC Q8DWB7.1
#=GS Q8DSA2_STRMU/6-59 AC Q8DSA2.1
#=GS LAFX_LACJO/1-57 AC Q48509.1
#=GS W7CPH2_9LIST/1-56 AC W7CPH2.1
#=GS A0A829I9L9_CLOBO/1-57 AC A0A829I9L9.1
#=GS Q8DVP7_STRMU/6-73 AC Q8DVP7.1
#=GS G5JMJ6_STRCG/6-59 AC G5JMJ6.1
#=GS LAFA_LACJO/1-75 AC P24022.2
#=GS A0A124GCG4_9HYPH/7-67 AC A0A124GCG4.1
#=GS A0A1I1FJW3_9LACO/1-57 AC A0A1I1FJW3.1
Q8DW08_STRMU/6-71 .......................FE....NFDEIDMNHLASIEGG..........------..-FDV.KGVAASYL.A.MGTA............--ALGGLACTTPVGAV-----lylgaevcagaaviyyga.......
G5JMJ7_STRCG/7-59 .......................FE....QFEAVDNETLAIVKGG..........--LSDC..AQGT.LATAALGA.A.TGGG............---PWGAVGGGLVGVA-----a........................
A0A139NHC3_9STRE/1-58 .................mttqiv-K....KFETLDIETLSHVEGG..........VNWAAC..YAGT.IGSALVGS.A.GGPV............-----GYWGGALVG-------yat......................
A0A5J5FWL1_9BACL/1-70 ...............mqyalsng--....-FVEMNSSELMEVNGG..........SWWKDA..VVGA.VVGGAAGV.I.RGAA............-MGALIGATAGPGGAVAGAI-scaay....................
A0A1E5G4L8_9FIRM/1-55 .......................MS....NLQALSHEELIGIEGG..........-----Y..GTDL.LKGAARGA.A.LGFV............--------AGGFAGAFVGAHVgvglag...................
A5M6F3_STREE/6-68 .......................MS....QFSVMDTEMLACVEGG..........------..GCNW.GDFAKAGV.G.GAAArg........lqLGIKTGTWQGAATGAAGGAILggv......................
A0A1K1P8M8_9GAMM/1-66 .......................--....-MRELTSPEIASVSGGrlk...vpgaCSRATL..LSNT.GVAALGGG.I.TGLI............TGGPLVGLGGAIFGGSMGA--ls.......................
A0A4R3YLK4_9GAMM/1-73 .......................--....-MQELTMNEIDEVSGGlmla.ppgidHSYERC..VGGFmLGGALFGA.A.IGVG............TTYGFGGATGFTVGATIG---qiagtyf..................
A0A553GSH8_9BACT/1-54 ..............mknlndlgv--....--QELSKKDMKKTDGG..........-----G..WRGA.IAGACLGA.M.TGNP............--------AGVLIGAIAGAF-i........................
L0KCR9_HALHC/1-56 ...............mnelstvg--....NFEELSEDEYLNVDGG..........---LVI..TGTA.VAAGVGCL.A.GGVT............--------VGYAIGT------viesv....................
A0A4U1B4N5_9GAMM/1-58 .......................--....-MRELNTNELNHVSGGtd......agDIAIAT..GGSW.AAT-VAGF.A.IGGP............----VGAVAGFALGT------lisvgy...................
R2SSJ5_9ENTE/1-55 .......................MQ....NVKELNIQKMQKITGG..........---NSC..TNGT.IGGAIAGA.P.GGPL............-SFLAGAAGGAVAGG------cik......................
A0A1A9HNN2_9BURK/1-62 ......................m-E....-LRELTLEEIEIVAGG..........-ISDAL..LSDI.GKGALAGG.F.AGFAv..........tGGTPVGFLGGAAVGAVGGAV-h........................
A0A139WTX4_9CYAN/1-70 ..........maiikitelqsvn--....QVEELSNEDLTSVVGG..........-----L..VGGL.LGPTEPGA.A.GGGPf..........dIIPIVGPLLSGLLGGFLGG--pa.......................
D9SPP3_CLOC7/1-71 .......................MT....NFETCTMDELVLIDGGdw.....swkSLAQST..VSGA.VGGAIAGS.A.GGTV............TLPVVGTVGGGVGGGILGAV-ggaaa....................
A0A139NEU2_9STRE/3-63 .......................FE....HFETLNENNLRDIYGG..........----NN..AGAA.VVAAMSCA.A.GGIKl.........ggKFGPWGAAIGGVGGAAICGY-l........................
Q5M2W2_STRT2/6-65 .......................IE....NFNTLDLETLASVEGG..........------..GCSW.GGFAKQGV.A.TGVGng........lrLGIKTRTWQGAVAGAAGGAIV.........................
Q8DSB5_STRMU/7-81 .......................LE....QFDAMDVDMLAAVEGGn.......wgQCIVGT..GSSA.LAGGLAGA.G.TGAAvsapa..aegggLGPIAGAAIGWDLGAISGAG-l........................
A0A347WMH6_9LACT/1-58 .................mntqti-S....QFELLDTELLATVEGG..........-ASGKC..IAGV.VVGALLGS.V.GGPW............-----GSAAGGAVGAG-----ff.......................
B7GL22_ANOFW/1-86 .......megvvftmelmlekng--....SISFLSEEELKEIDGGrgs...wtnaVIGAGT..LSPI.VASAVRGA.Q.QGVRf.........grLGGPWGVVAGAVVGAVVGGYL.........................
A0A371QME9_9BACT/6-68 ..........klpnnikannpnn--....NLSLLDDNELKSINGG..........AKPVAP..LFGW.KAAALLVG.G.TGAA............--IIVGVAGT-----------yll......................
A0A2L0D506_9STRE/1-64 .....................mg--....---ELNFEQLSQIRGG..........---GKK..AADI.YVSAISGA.A.QGAMlca.....qtgvVVQPGVILGCAGAGAVLGVM-fp.......................
A0A1I7JF40_9FIRM/1-74 .......................MEn..tMFYEIENEQLFNVEGG..........-NVVGD..AATI.LGAGAAGA.E.IGGA............----IGGAIGGPGGAFTGGVVggaigvgcgvmivvt..........
A0A5C5TCW4_9STRE/1-50 ....................melMN....KFEEMTTEELATVDGG..........---MGV..LAVI.GYSVLAGT.G.VGIV............GYGV-----------------arifg....................
J0V0Y6_STREE/4-49 .....................kmMS....QFAVMDNEMLACVEGG..........------..--DI.DWGRKISC.A.AGVA............----YGAI-------------dgcattv..................
A0A3N2KW95_9BACT/2-68 qyavelqnqpvsrgigdsilsav--....----------------..........KCIAGT..AGSA.GLGFLAGA.G.VGTV............TLPVVGTVSGGAVGGWSGAL-v........................
A0A1I1FLD5_9LACO/3-67 ....................qlt--....--NTLTSQELAEISGGys......rgQCYKAM..ASGA.AWGALRGG.M.SGTF............AGGPVGTIGGAIAGAHLGAI-g........................
A0A7X6MYB5_9STRE/6-65 .......................ME....RFNTLNAETLATVEGG..........------..FWGL.FLGGAISA.F.DGGP............---------------------tleqlngkklptprscspygtggtp
B7GL23_ANOFW/1-65 .......................MR....MFQELNHVELQGIDGGs.......wkSHVVNL..VGVV.SGFGTTGA.V.IGGS............----FGGPLGAAAGGFVGAH-ygava....................
A0A109RHX2_9LACT/5-63 ....................hek--....---TIKAERLLKIKGG..........----GK..RTDV.ASNMLSWA.A.AGYRi.........cpAYKPVCAVVGGAAGAAYG---awg......................
A0A6V7TKH7_9BILA/4-44 ....................eke--....----------------..........-----T..VDNV.ATGIMSGA.A.TGTI............VAGPVGAAVGAGIGAAIG---li.......................
A0A1M5QU89_9FIRM/1-76 ...............memtlnin--....SFNELTNDELMLVNGG..........---EWS..WGAF.FGSVFKGM.E.KGYHdadpnattkvpyIGEVPAPIVGALVGGIHGA--i........................
A0A172Q637_9STRE/6-62 .......................LE....QFVTLTDTELSAVEGG..........KNKDGR..DLAC.VLGTAGMA.G.AGFL............FAGPGGAA---VLGG------atal.....................
J1NZV6_STREE/1-61 .................mntycn--....----INETMLSEVYGG..........----NS..GGAA.VVAALGCA.A.GGVKy.........grLLGPWGAAIGGIGGAVVCGY-l........................
Q8DSB1_STRMU/10-94 ..........mdemriymmeikaLD....QFETMDTDMLAAVEGGfgwdsiwrgfKCVAGT..AGTI.GTGALGGS.A.TGGL............TLPIIGHVSGGIIGGISGAG-v........................
A0A380KA75_9STRE/5-72 .......................MK....QFEVMNEQQLVAVEGG..........KVNWGR..IGMC.ALSVAAGA.G.Q--Aymst....aggtAFLGPYAIGTGAIGAIIGGA-g........................
J1P4N6_STREE/6-65 .......................MS....QFEIMDTEMLACVEGG..........------..GCNW.GDFAKAGV.G.GGAArg........lqLGIKTRTWQGAATGAVGGAIL.........................
A5M6F0_STREE/6-63 .......................ME....QFSVMDNEELEIVSGGrg.....nlgSAIGGC..IGAV.LLAAATGP.I.TGGA...........aTLICVGS--------------gits.....................
A0A4Y9HE79_9BACL/4-53 ....................llv--....--KELTFEELLVVDGG..........TNWAGL..ASCT.LGATVGGA.V.GGLV............GVAG-----------------ygatcw...................
T1ZF07_STRIT/6-72 .......................LE....KFEVLNSEMLASVEGGkrp...ggapVTGMTQ..AHYT.CLAATWGA.T.FGGM............LAPI-----------------sligsvpgvlaacsg..........
A0A437SU16_9LACO/11-81 ....................ylk--....----LKENELNKVLGGis......krNKVKRC..AKEI.FGSAATGA.A.SGAVrg........tfVEPGYGTLGGALMGAAGGI--fsggam...................
W7CGP1_9LIST/1-77 .......................MH....KVKKLNNQELQQIVGGys......skDCLKDI..GKGI.GAGTVAGA.A.GGGL............-----AAGLGAIPGAFVGAHFgviggsaaciggllgn.........
G5JPG8_STRCG/6-49 .......................LE....QFDVMDEQALAAVEGG..........------..-GYW.DDYPLVGA.A.AGVL............----FG---------------tggyllqn.................
Q1WQX8_LIGS1/1-65 .................mknldk--....RFTIMTEDNLASVNGGkngy..ggsgNRWVHC..GAGI.VGGALIGA.I.GGPW............---------SAVAGGISGGF-t........................
A0A383U1V8_9FLAO/1-51 .......................ME....NIKTLSYQEMQEIEGG..........-IAPFIiaGAYI.AGSFVAGL.T.VGAV............SAHIVY---------------els......................
I5BT60_9BACT/1-80 .mkggrflkilnrvgvkqnlfim--....QFEELNNNELAEVNGG..........-----L..LGGL.LGGVLGGN.N.SGQN............-------ASGGLLGGFLGGL-lggnnsggfgs..............
L0KBX3_HALHC/1-64 ...............mdnlasvg--....-MVELNEEELMMVDGG..........---FFS..VTDL.GWAAAGGA.I.SGAI............TYGSIGGAPGAVAGAFTGAAL.........................
Q9PCT5_XYLFA/1-72 ...mdiailvyrdvylnsfkesl--....KMRELTFEEALKVDGQ..........------..--GW.AGAFLTGA.G.TGAY............AGGLIAEVPGAVVGAVVGGV-i........................
A0A145WNP8_9GAMM/30-71 ..................skksr--....----------------..........------..FSPT.VKGALIGA.A.AGSV............-LPVFGTISGAVIGAVSG---kiy......................
A0A7W9SVB4_9BACT/30-93 ...................qrlv--....------HEHLDGIQHGldd...dpnnDPAKGS..VLGA.TGGAVVGA.V.AGAV............-LGPVGAALGALAGAAAGAI-a........................
T1ZF76_STRIT/6-66 .......................LE....KYEVLNSEMLASVEGG..........YNTSDC..LKDY.GKGFLSGT.A.AGAA............-WGSIAGGIGALPGAFVGAHV.........................
A0A8J3CXR3_9BACT/1-58 .......................--....-MKELSIDRMEMVSGG..........LFSQIC..KSDA.DYFFLGSV.A.AGII............CGGGVGYAVGLAIGGIGG---dl.......................
A0A1M5QU07_9FIRM/1-73 .................mtlnin--....TFNELTYNELMLINGGew.....nwyAFFDAV..VGGA.VSGAIAGS.A.VGTM............TIPLIGEVPGVIGGAVIGAI-gga......................
D9SR35_CLOC7/1-57 .......................ME....NFVSLTEVELHEIEGGrw......swKKIAKV..AFAV.IKTATTIA.S.GGAV............---IPAV--------------ikgaitii.................
I0XAR7_9SPIR/66-123 ....................kes-E....NTEYLSEDALEEVAGGs........vTSWMHR..NKDW.VIAATALA.T.IGAC............---------------------ymfnkylekksaa............
A0A4Q7PJR5_9FLAO/1-62 ......................m--....--KTLEINKMESIQGG..........DCVEET..VSAG.VKGAVGGA.I.TGALa.........ggVGALPGAAGGWLVGALS----glva.....................
A0A4Q1SLZ3_9BACL/1-64 .......................ME....KLMVLNEEKLSYVIGGgnp....kvaHCASQI..GRST.AWGAVSGA.A.TGTA............----VGQAVGALGGALFGGS-m........................
A0A172Q9E3_9STRE/1-41 .......................MElavnKFVELTDEELMEIEGG..........-----G..VGVA.IALFMAGY.T.IG--............---------------------kdi......................
B2JC36_NOSP7/16-67 ...................evll--....--SELSDEEMATIQGG..........--SNAP..AEVL.AVCAVGGA.V.LGGP............--------AGFLGGAFVGAIL.........................
A0A6A0BAV4_9LACT/7-53 .......................LD....NFSSLTKDEMMMVEGG..........---AIN..VGNL.VKAIGAVY.A.AGYA............----VGSFV------------gnll.....................
A5CZV1_PELTS/2-58 .......................LE....QSDELSEEELEQVAGG..........------..-GVL.ALVALGLY.A.AGAT............---AVGVGVGAVAGAALAG--avvgvta..................
D9SR36_CLOC7/1-58 .......................ME....NFKTLSEVELHQIDGGkw......kwKKIIKI..AAAV.AGTVVTIA.S.GGAA............-------APAVIGGA------iavan....................
T1ZF04_STRIT/6-65 .......................LE....KFEALNSEMLARVEGG..........------..GCNW.GDFAKSGI.A.GGAGng........lrLGIKTRTWQGVVAGAIIGGV-g........................
Q8DWB6_STRMU/1-76 ................mewrintMElnvnNYKSLTNDELSEVFGG..........---DKQ..AADT.FLSAVGGA.A.SGFTyca......sngVWHPYILAGCAGVGAVGSVVF.........................
A5CZV3_PELTS/2-56 .......................LE....QSDELSEEELEQVAGG..........-VWPGI..VAGV.ALVGAGVAlA.AGAG............-------VALAGAGALAAAIL.........................
I5BT61_9BACT/1-70 .mkgrrflkilnrvgvkqnlfim--....QFEELNNNELAEVNGG..........-----I..LGGL.LGGLLGGN.N.FGQS............------ASSGALLGG------lnlti....................
A0A4Y9HC61_9BACL/5-68 .....................lv--....--KELTFEELLVVDGG..........TNWAGL..ASCT.LGATVGGA.A.AGFA............-----FAGVGAGAGALLG---fnyglgacmlag.............
D9SSI4_CLOC7/7-70 .......................-E....NFTDLRIDEIEFINGGm.......sdWDWVWC..GVVT.AGCTVIGA.A.IGTA............VCPGIGTIGGANAGSVLGGIF.........................
A0A380KA66_9STRE/2-55 ...................mtav-E....QFEALNEDKLELIEGGd.......waKCVLGT..TSIA.RLRYLSGG.V.VGGW............--------SG-----------vlegv....................
Q5FI73_LACAC/1-64 .......................ME....KLMVLNEEKLSYVIGGgnp....kvaHCASQI..GRST.AWGAVSGA.A.TGTA............----VGQAVGALGGALFGGS-m........................
A0A1H1YFL4_9BACL/5-73 ..................ltnnl--....-FHEMDVDQLLMVDGGdw.....sfkDFWKDT..AKGA.VGGAISGG.V.GGAV............ATGGPGVIPGAVAGGIVGAA-g........................
A0A4Q9XLL5_9ALTE/26-84 .....leqqrelqedqnkrmkkq--....----------------..........QNATAA..GTGA.IAGAYAGA.E.AGSV............-GGPWGAVIGAVAGYI-----lse......................
A0A4Y9F9Q7_9STRE/1-61 .......................--....----MTDVELVEVIGGg.......wvQCGLGT..VGGA.LTGAVAGA.A.VGTV............TLPVIGTVSGSAVGFWGGGS-aga......................
B9DTX8_STRU0/1-88 ....mekllfqkrkvdilmnsni--....EFDSIDTELLEKVIGG.........kNNWQAN..VSGI.LAAGAAGA.A.IGAPvcglacgyigakTAITLWAGVTGATGGF-----k........................
Q8DRN0_STRR6/6-65 .......................MS....QFEIMDTEMLACVEGG..........------..GCNW.GDFAKAGV.G.GGAVrg........lqLGIKTRTWQGAATGAAGGAIL.........................
A0A139NEK0_9STRE/1-72 ..................manvd-K....QFQVLTAEELMEIHGGn.......nyGHYNPS..AQDI.LKAAASGA.IqVGATc..........lPAGAWAVAGCALVGGLWGGY-i........................
A0A7Y0HTM2_9BIFI/5-52 .......................MA....QFDSLQEDALMQVEGG..........------..---V.VITATTCA.A.IGLG............-----IAVVGLAAGIFVGAHL.........................
A0A4Y9FJR2_9STRE/8-70 ...................ltyy--....--EKLDTKNLVEVRGG..........---GAR..EGDM.FLSAAAGA.A.NGIAmca.....qfglYIPWQGYAVCAVGGAA-----sn.......................
Q9A139_STRP1/2-63 .....................ik--....FAEEIQKEELFHIIGG..........YSATDC..KNHL.IGGITSGA.I.AGGV............GAGMATLGVGGVAGAFAGAHV.........................
Q8DSA3_STRMU/1-62 .......................MEkqynNFKILNTDALENIQGGgr.....aprCAALVG..ASIY.DGLAVVGD.P.VGVA............-----MAAGTIAAGSF-----c........................
Q1WQX7_LIGS1/2-62 .......................MK....EFTVLTECELAKVDGG..........KRGPNC..VGNF.LGGLFAGA.A.AGVP............-LGPAGIVGGANLGMVGGA--lt.......................
M9L947_PAEPP/1-82 .......................MS....RFVELNRNELEQVDGGgfsw..eglgKCVAGT..AGGV.VAGGTSGF.L.AGVSa.........grAGGPQATAAGGTIGGVGGAI-gggltgaaas...............
G6ERX6_STRTR/6-68 .......................IE....NFNTLDLETLASVEGG.........gCSWGGT..GGAT.VQGAIGGA.F.GGNV............VLPVVGSVPGYLAGGVLGGA-g........................
A0A7G9BI36_9SPHI/2-71 ..............rtlsvenlg--....-LEELSNQDLVDVNGGt.......tlRCNAGA..AGSA.IGGALTGA.A.AGSV............-IPVIGTLGGAAIGALGGAL-l........................
A0A2L0D508_9STRE/1-69 .......................ME....QFEVMDEMALSNIEGG..........----ND..VLIT.AGSAIAGG.I.VGYLac.......sasIVAAPVAGACAYTGAKIGGA-gyliarh..................
A0A1G6X8W7_9GAMM/1-54 .......................--....-MQTLSNIQLEQVGGG..........--NECH..VNTV.AGAAMVGA.G.VGFL............----LGGPIGAAAGAISAG--gha......................
J0VAC6_STREE/6-48 .......................ME....QFSVMDNEMLDRIEGG..........---IFG..VDDA.LFWAGLGY.V.AGS-............---------------------ivdtai...................
F5IUS8_9BACT/1-57 ...........mekelttlnets--....EFKELTKEEMAAINGGya......igDYLKDL..YESA.GAAVAAGA.A.AGAA............---------------------ai.......................
A0A172Q635_9STRE/1-59 .......................ME....QFQLIEDNELEMIVGG..........KVSPTC..AALV.AASIYGGL.A.IAGP............----VGVGVAMATGGVAAGSFc........................
Q8DS95_STRMU/6-71 .......................FE....QFNVMDNEALSAVEGG..........----GR..GWNC.AAGIALGA.G.QGYMata......ggtAFLGPYAIGTGAFGAIAGGI-gga......................
A0A172Q613_9STRE/6-66 .......................FE....QFATLTDAELSAVEGG..........------..GCNW.RDADKAGV.A.GGIG............-----GLIGGGPVGGIAGIA-gglaaygatcw..............
H8KYJ8_FRAAD/1-71 .......................--....-MMELDSTQVDQIQGG..........ASATAI..IGAV.IGGALTGG.A.IGST............----VGAAIGGPIGAGFGGAFgviaggagasftaaah.........
Q8DWB7_STRMU/6-52 .......................FE....QFDVMDSQTLSTVEGG..........------..---K.VSGGEAVA.A.IGIC............------ATASAAIGGLAGATL.........................
Q8DSA2_STRMU/6-59 .......................LE....QFDVMDSQVPSAIEGG..........------..GCSW.KGADKAGF.S.GGVG............---GLIGAGGNPVGGVLGIA-gg.......................
LAFX_LACJO/1-57 .....................mk--....----LNDKELSKIVGG..........----NR..WGDT.VLSAASGA.G.TGIKa.........ckSFGPWGMAICGVGGAAIGGYF.........................
W7CPH2_9LIST/1-56 ....................mkk--....--ELLNKNEMSRIIGG..........---KIN..WGNV.GGSCVGGA.V.IGGA............----LGGLGGAGGGCITGAI-gsi......................
A0A829I9L9_CLOBO/1-57 ......................m--....--ENINLNELQEINGG..........----MT..AGGV.LYATGKGA.V.TGAL............TGAGFGGAPGAILGAVYGAPFga.......................
Q8DVP7_STRMU/6-73 .......................FE....QFNVMDNEALSTVEGGg.......miRCALGT..AGSA.GLGFVGGM.G.AGTV............TLPVVGTVSGAALGGWSGAAVgaa......................
G5JMJ6_STRCG/6-59 .......................LE....QFDVVDEKTLSEINGG..........----DG..VAQC.IIGTAGGA.I.WGNA............AFGLIGAGVGTFIG-------ntv......................
LAFA_LACJO/1-75 .......................MK....QFNYLSHKDLAVVVGG.........rNNWQTN..VGGA.VGSAMIGA.T.VGGTicgpacavagahYLPILWTAVTAATGGFGK---irk......................
A0A124GCG4_9HYPH/7-67 ....................nva--....----LNDEALDSVSGGfn......lyDSICNI..GDAV.EKSIQSGV.E.IGIY............-AGPPGVLAGAFGGAFYGA--l........................
A0A1I1FJW3_9LACO/1-57 ...................mnle--....-IKVLNNNQLSKITGGk........kINWGSV..GGSC.IKGALFGA.A.FGGN............-------AIGGCAGSA-----aada.....................
#=GC seq_cons .............................phptLspppLtplpGG..............th..sssh.ssuuhuGu.u.sGss................hushsGuhsGuhhuh..h........................
//
