#=GF ID   Bacteriocin_IIi
#=GF AC   PF11758.12
#=GF DE   Aureocin-like type II bacteriocin
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Lonsdale D
#=GF GA   25.00 25.00;
#=GF TC   26.00 40.40;
#=GF NC   24.20 17.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12054867
#=GF RT   Biochemical characterisation and genetic analysis of aureocin
#=GF RT   A53, a new, atypical bacteriocin from Staphylococcus aureus. 
#=GF RA   Netz DJ, Pohl R, Beck-Sickinger AG, Selmer T, Pierik AJ, Bastos
#=GF RA   Mdo C, Sahl HG; 
#=GF RL   J Mol Biol. 2002;319:745-756.
#=GF RN   [2]
#=GF RM   12406714
#=GF RT   Mode of action of the antimicrobial peptide aureocin A53 from
#=GF RT   Staphylococcus aureus. 
#=GF RA   Netz DJ, Bastos Mdo C, Sahl HG; 
#=GF RL   Appl Environ Microbiol. 2002;68:5274-5280.
#=GF DR   INTERPRO; IPR020968;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a small family of type II bacteriocins usually encoded
#=GF CC   on a plasmid. Characteristically the members are small,
#=GF CC   cationic, rich in Lys and Try, and bring about a generalised
#=GF CC   membrane permeabilisation leading to leakage of ions. The family
#=GF CC   includes aureocin A, lacticins Q and Z, and BhtB as well as an
#=GF CC   archaeal member.
#=GF SQ   11
#=GS Q576C5_CORJK/1-52           AC Q576C5.1
#=GS A0A024Q648_9BACI/1-48       AC A0A024Q648.1
#=GS A0A2N9JGY4_9ACTN/5-56       AC A0A2N9JGY4.1
#=GS A0A2W0CG83_9MICO/1-52       AC A0A2W0CG83.1
#=GS A0A3P1WLC2_9ACTN/2-53       AC A0A3P1WLC2.1
#=GS A0A1I2PND2_9FIRM/1-42       AC A0A1I2PND2.1
#=GS A0A494ZVK6_9BACI/1-48       AC A0A494ZVK6.1
#=GS A0A494ZW46_9BACI/1-48       AC A0A494ZW46.1
#=GS A0A494ZVC4_9BACI/1-48       AC A0A494ZVC4.1
#=GS A0A7G9T4A2_9LACO/1-49       AC A0A7G9T4A2.1
#=GS A0A4Y1WE58_BACAN/2104-2150  AC A0A4Y1WE58.1
Q576C5_CORJK/1-52                      ....MAgFLKVVKAVAKYGSKAVKWCWDNKGKIL.EWLNIGMAVDWIVEQVRKIVGA.............
A0A024Q648_9BACI/1-48                  ..ma--.--AFLKLVAQLGTKAAKWAWANKGTVI.NWIKNGATFSWISDKIDSII--n............
A0A2N9JGY4_9ACTN/5-56                  ...w-SiFLRIVALIAKYGKRAVDWCWANRNRIY.DWIRNGMAVDWIINRILEILGL.............
A0A2W0CG83_9MICO/1-52                  ....MAvFARILQLLARYGARAVAWAKAHVQQVL.NWINIGQAIDWIVSKIKQILGI.............
A0A3P1WLC2_9ACTN/2-53                  .lsi--.FAQVLRVIARYGANAVKWVYANRVRVM.GWIRDGLAVDAIVSRIKQALGI.............
A0A1I2PND2_9FIRM/1-42                  ....M-.FAKLLKFTSKYGTKAVKWCWKHKWELL.N---------------------assaaydiikdlf
A0A494ZVK6_9BACI/1-48                  ...m-A.--TFLRLVAQLGSKAAKWAWNNKGRVL.DWIRNGMAIEWIIDKINSII--n............
A0A494ZW46_9BACI/1-48                  ...m--.-LAFLRLVGQLGSKAAKWAWDNKGRVL.EWLRDGMSFSWIVDKIEDIV--n............
A0A494ZVC4_9BACI/1-48                  ..mv--.--TFLRLVAQLGSKAAKWAWDNKGRVL.DWIRNGMAFDWIIDKINSIV--n............
A0A7G9T4A2_9LACO/1-49                  ..ma--.--VILDALAAAGSTVLNWGKNNIGTII.KWLNAGQAIDWIINKIKQILH-i............
A0A4Y1WE58_BACAN/2104-2150             akya--.----IRYGAKYGKKAVKSGWDYGKKVAkSGWNKGKS---IAQKIPRIHKV.............
#=GC seq_cons                          ...h.....phL+llAphGoKAlKWuWsN+s+Vl.sWlpsGhAh-WIlsKIppIl...............
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