#=GF ID Bdbt-like_TPR
#=GF AC PF21603.1
#=GF DE Bride of doubletime-like, TPR domain
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE ECOD:EF20451
#=GF GA 27.00 27.00;
#=GF TC 27.00 27.90;
#=GF NC 26.20 25.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF CL CL0020
#=GF RC Paper describing PDB structure 4it4
#=GF RN [1]
#=GF RM 24210908
#=GF RT Noncanonical FK506-binding protein BDBT binds DBT to enhance its
#=GF RT circadian function and forms foci at night.
#=GF RA Fan JY, Agyekum B, Venkatesan A, Hall DR, Keightley A, Bjes ES,
#=GF RA Bouyain S, Price JL;
#=GF RL Neuron. 2013;80:984-996.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found at the C-terminal end of Bride of
#=GF CC doubletime from Drosophila melanogaster (Bdbt) and similar
#=GF CC proteins predominantly from arthropods. Bdbt is a mediator of
#=GF CC the effects of the kinase Doubletime on the key circadian
#=GF CC transcriptional regulator Period. This entry represents the
#=GF CC entirely alpha-helical TPR domain [1]. It is normally found
#=GF CC associated with Pfam:PF18023.
#=GF SQ 59
#=GS A0A6J0BK88_NEOLC/123-206 AC A0A6J0BK88.1
#=GS B3M2V8_DROAN/127-211 AC B3M2V8.1
#=GS A0A7E5WRD0_TRINI/33-116 AC A0A7E5WRD0.1
#=GS A0A0L0CM86_LUCCU/128-212 AC A0A0L0CM86.1
#=GS A0A067RVR2_ZOONE/129-211 AC A0A067RVR2.1
#=GS A0A151J954_9HYME/132-215 AC A0A151J954.1
#=GS A0A6J3K664_9HYME/129-212 AC A0A6J3K664.1
#=GS A0A834UHA1_VESPE/127-210 AC A0A834UHA1.1
#=GS A0A8J5AI91_9DIPT/133-223 AC A0A8J5AI91.1
#=GS E2AR15_CAMFO/130-213 AC E2AR15.1
#=GS A0A310S7N3_9HYME/130-212 AC A0A310S7N3.1
#=GS B4IKK6_DROSE/127-211 AC B4IKK6.1
#=GS A0A0N0BHV3_9HYME/129-212 AC A0A0N0BHV3.1
#=GS A0A6P4J764_DROKI/127-211 AC A0A6P4J764.1
#=GS A0A2A3ETS3_APICC/220-303 AC A0A2A3ETS3.1
#=GS A0A0M4EP15_DROBS/125-209 AC A0A0M4EP15.1
#=GS A0A836JP41_9HYME/134-217 AC A0A836JP41.1
#=GS A0A182G133_AEDAL/319-404 AC A0A182G133.1
#=GS B4LWU7_DROVI/123-207 AC B4LWU7.1
#=GS F5HMS3_ANOGA/95-180 AC F5HMS3.1
#=GS A0A151X9K9_9HYME/134-217 AC A0A151X9K9.1
#=GS F4X8E6_ACREC/108-191 AC F4X8E6.1
#=GS A0A834U6G5_VESGE/127-210 AC A0A834U6G5.1
#=GS A0A7M7LNY9_NASVI/128-208 AC A0A7M7LNY9.1
#=GS A0A6I9WRI6_9HYME/129-212 AC A0A6I9WRI6.1
#=GS A0A836GFU1_9HYME/135-218 AC A0A836GFU1.1
#=GS B4NIQ1_DROWI/121-205 AC B4NIQ1.1
#=GS A0A6P3XQ95_DINQU/130-212 AC A0A6P3XQ95.1
#=GS A0A6J2TG92_DROLE/127-211 AC A0A6J2TG92.1
#=GS B4JFI6_DROGR/121-205 AC B4JFI6.1
#=GS B4KDL5_DROMO/123-207 AC B4KDL5.1
#=GS A0A8N4L7L2_BACDO/109-193 AC A0A8N4L7L2.1
#=GS W5JJ68_ANODA/450-535 AC W5JJ68.1
#=GS A0A6J1PFU5_9HYME/135-218 AC A0A6J1PFU5.1
#=GS A0A158NBV8_ATTCE/134-217 AC A0A158NBV8.1
#=GS A0A2P8YGL9_BLAGE/137-220 AC A0A2P8YGL9.1
#=GS W8BMD2_CERCA/129-213 AC W8BMD2.1
#=GS A0A6P4E6H4_DRORH/127-211 AC A0A6P4E6H4.1
#=GS B4GEK7_DROPE/127-211 AC B4GEK7.1
#=GS A0A6P8XL29_DROAB/124-208 AC A0A6P8XL29.1
#=GS A0A7E5WRK4_TRINI/130-213 AC A0A7E5WRK4.1
#=GS A0A0J7KC95_LASNI/130-213 AC A0A0J7KC95.1
#=GS A0A7R8UQJ0_HERIL/93-177 AC A0A7R8UQJ0.1
#=GS E2B5K7_HARSA/130-213 AC E2B5K7.1
#=GS A0A6I8VBF3_DROPS/127-211 AC A0A6I8VBF3.1
#=GS A0A6V7H010_9HYME/129-194 AC A0A6V7H010.1
#=GS A0A182YGG5_ANOST/458-543 AC A0A182YGG5.1
#=GS A0A4S2KWH7_9HYME/460-543 AC A0A4S2KWH7.1
#=GS Q9VDE4_DROME/127-211 AC Q9VDE4.1
#=GS A0A7M7MKI0_APIME/127-210 AC A0A7M7MKI0.1
#=GS A0A836EFD4_9HYME/135-218 AC A0A836EFD4.1
#=GS A0A3B0KEE4_DROGU/127-211 AC A0A3B0KEE4.1
#=GS A0A084W577_ANOSI/16-97 AC A0A084W577.1
#=GS A0A6I8T9V7_AEDAE/136-221 AC A0A6I8T9V7.1
#=GS A0A026X140_OOCBI/48-133 AC A0A026X140.1
#=GS T1GYE6_MEGSC/121-203 AC T1GYE6.1
#=GS A0A232FA50_9HYME/128-208 AC A0A232FA50.1
#=GS A0A6P4JM59_DROKI/100-184 AC A0A6P4JM59.1
#=GS A0A154P472_DUFNO/129-212 AC A0A154P472.1
A0A6J0BK88_NEOLC/123-206 ...s-AKEKYDVALYYKEAGVRLYKS.S.R.IVdA.FSKFSKACKILISLEPIPESDIED......S--.LR.NDI.EHLRRILYNNMAECHLTRKNFEHTV-s............
B3M2V8_DROAN/127-211 ....NAAETYDLALRLKESGVATFKA.Y.P.KF.A.FDYFTRSAKLLITYKPFDKLTKKS......NGI.NG.STV.EELFIQIQTNLAACFLQEKRYEHVIY.............
A0A7E5WRD0_TRINI/33-116 .swe---RLYEAAVHHKERGVELFKQ.G.RaVD.A.FRRFNKALKMLIATEPLDPAVVSE......EVV.--.KDM.VNLKVKLYNNLAHCQLQFNEYDA---tlk..........
A0A0L0CM86_LUCCU/128-212 ...t-VPEMYELASKYKENGVKMFKK.Y.P.IF.A.HEYFAKAAKCLISYKNFEGLTKKR......DGV.AG.KDM.QELFIQIQTNLAACLLNEKRYDDVLY.............
A0A067RVR2_ZOONE/129-211 ndsk----KYELAMYHKVRGVELYRCgR.T.RD.A.FLRFSKAIKFLITIIPVEDYTS--......-AV.QR.DDV.MSLRVILCNNIASCQLQYKNYCHVI-k............
A0A151J954_9HYME/132-215 ...s-AEEKYQVALRYKERGTELFKE.F.R.IIdA.FRKFSKACKLLITLEPIADLKLDK......Q--.LE.YNI.NNLRLALYNNMAICQLKRKNYQHVV-t............
A0A6J3K664_9HYME/129-212 tpqd----KYSIALTYKEAGVCLFQK.H.R.YVdA.FYKFSKACKILITLEPIQDLELDK......-TL.E-.TKI.NNLRLILYNNMAGCQLSRKNYEHTI-s............
A0A834UHA1_VESPE/127-210 ..tp--EEKYEIALKYKEVGVKLFKE.S.R.HIdA.FHKFSKACKILITLEPIPDLELDK......S--.LE.KNI.NSLRIILYNNLAGCHMLNKNYEHII-k............
A0A8J5AI91_9DIPT/133-223 ..sp--KELFEIASKYKEQGVKMYKK.Y.P.AF.A.QNYFNLAAKLLISLKPFNTLDDREanesfrHQI.DQ.QSL.QQLHDGIYLNIAAGLIKQNRYEDALY.............
E2AR15_CAMFO/130-213 ...t-AEEKYKIALRYKERGVELFKD.S.R.ITdA.FYKFSRACKLLITLEPIADLDLDK......Q-L.-E.SSI.NELRLALYNNMAMCHLSRKNYKHTI-t............
A0A310S7N3_9HYME/130-212 penk-----YLTALKYKETGVSLFKE.N.R.FV.DgFYRFSKACKILITLEPIPDLELDT......K-L.-E.SKI.NNLRLVLYNNMAGCQLNCKNYEHTI-s............
B4IKK6_DROSE/127-211 ...s-AAEIYELALRLKQSGVATFKT.F.P.KF.A.FDYFVRAAKLLITYKPFDKLNKKT......NGI.NG.PAV.EALFIQIQTNLAACLLQEKRYEHVIY.............
A0A0N0BHV3_9HYME/129-212 ..tp--EEKYSVALKYKETSIGLFKE.G.R.YVdA.FYRFSKACKILITLEPIQDLELDK......-TL.-E.SNI.YNLRLVLYNNMAGCQLNRKNYEHTI-s............
A0A6P4J764_DROKI/127-211 ...d-AAGMYDLALRLKESGVATFKS.Y.P.KF.A.FDYFARAAKLLITYKPFDKLTKRE......NGI.NG.STV.EELFIQIQTNLAACLLLEKRYEHVIY.............
A0A2A3ETS3_APICC/220-303 ..tp--EEKYNIALKYKETGVYLFKE.Q.R.WVdA.FYRFSRACKILITLEPIRDLELDK......E-L.E-.NNI.NNLRFVLYNNMAGCQLNRKNYEYTI-s............
A0A0M4EP15_DROBS/125-209 ...k-GAELHKLALQYKENGVAMYKT.Y.P.KF.A.FDYFVRAAKLLITYKPFDKLDSKI......EGI.EG.SEL.ETLFVQVQTNIAACMLQEKRYEHVIY.............
A0A836JP41_9HYME/134-217 ...s-AKEKYQIALRYKERGTELFKE.F.R.IIdA.FRRFSKACKLLITLEPIADLELDK......Q-L.-E.YNI.NNLRLALYNNMAICQLKRKNYQHVV-t............
A0A182G133_AEDAL/319-404 ..sp--KEILVLAKTYKENGVKMFSK.Y.P.VF.A.HSYFNRAAKCLLSCAPLEGLDPAQ......EGE.ETiTEM.QTLLETLYLNISACLIKEHRYDEVL-q............
B4LWU7_DROVI/123-207 ....NAAEIYKLALSYKENGVAMFKE.H.P.KF.A.CDYFSRAAKLLITYKPFDKLDKKT......NGI.DG.SQL.QILFVQIQTNLAACFLLEKRYEHVIY.............
F5HMS3_ANOGA/95-180 ...t-VPETLALAKQYKENGVKMFSK.Y.P.LF.A.HAYFNQAVKCLLSWSPIDQLDPAI......EGA.GTiEEM.QSLLETLYLNIAACLIKQNRFDEVL-h............
A0A151X9K9_9HYME/134-217 ...s-AEEKYQVALRYKGRGTELFED.S.R.IIdA.FRRFSKACKLLITLEPIADLKLDK......Q--.LE.YNI.NNLRLALYNNMAICQLKRKNYQHVI-t............
F4X8E6_ACREC/108-191 ...s-AKEKYQVALRYKERGTELFKE.F.R.IIdA.FRRFSKACKLLITLEPIADLELDK......Q-L.-E.YNI.NNLRLALYNNMAICQLKRKNYQHVV-t............
A0A834U6G5_VESGE/127-210 ..tp--EEKYEIALKYKEVGVKLFKE.S.R.HIdA.FHKFSKACKILITLEPIPDLELDK......S--.LE.KNI.NSLRIILYNNLAGCHMLNKNYEHII-k............
A0A7M7LNY9_NASVI/128-208 ...s-LEEKYQTALKYKEKGVELFKA.K.R.NVdA.FHRFSKACKTLITLEPIEETDETM......KNI.--.---.LTLKYVLYNNMAECQLIQENYEHTI-t............
A0A6I9WRI6_9HYME/129-212 ..tp--EEKYEVALRYKERGMELFNC.SrV.TD.A.FHKFSRACKLLITLEPITDLELDK......Q-L.-E.YNI.NDLRLALYNNMAICHLKQKNYQHVL-t............
A0A836GFU1_9HYME/135-218 ...s-AKEKYQIALRYKERGTELFKE.F.R.IIdA.FRRFSKACKLLITLEPIADLELDK......Q-L.-E.YNI.NNLRLALYNNMAICQLKRKNYQHVV-t............
B4NIQ1_DROWI/121-205 ....NAAEIHNLALAYKECGVQMFKA.Y.P.KF.A.FDYFSRAAKLLITYKPFDKLTLKS......NGI.NG.SAV.EALFLQVQTNLAACMLQEQRYEHVIY.............
A0A6P3XQ95_DINQU/130-212 ..sp--EEKYQVALKYKEIGIELFKS.S.R.CVdA.FYKFSKACKILITLEPMSELEDK-......--L.LQ.SNI.ENLRLTLYNNMASCQLNQKNFEHTV-a............
A0A6J2TG92_DROLE/127-211 ...t-AAEIYDLALRYKTNGVAMFKD.Y.P.KF.A.FDYFIQAAKLLITYKPFDKLTKAS......NGI.DG.SEV.EALFVQIQTNLAACLLQEKRYEHVIY.............
B4JFI6_DROGR/121-205 ....NAAEIHKLALRYKENGVAMFKS.Y.P.KF.A.FDYFSRAAQLLITYKPFKTLDKKT......NGI.DG.AEM.ETLFIQIQTNLAACLLLEQRYEHVIY.............
B4KDL5_DROMO/123-207 ...s-AGEMYNLALKYKEKGVAMYKA.Y.P.KF.A.CDYFSRAAKLLITYKPFDKLDKQK......NGI.AG.NEM.EQLFVQIQTNLAACMILEKRYEHVIY.............
A0A8N4L7L2_BACDO/109-193 ....NVAEMYALAMRYKENGVVMFKQ.Y.P.YF.A.HAYFSRAAKFLISYKPFEGLTLHK......DGI.SS.EEM.QMLFTQIQTNLAACLLNEQRYDDVLY.............
W5JJ68_ANODA/450-535 tats----ALELAKRYKANGVLMYPK.Y.P.TF.A.QAYFNRAAKCLMSWSPIEQLDPAI......EGPgKI.EEM.QALLQTLQLNISACLIKENRYEEAL-h............
A0A6J1PFU5_9HYME/135-218 ...s-AEEKYEVALRYKERGAELFKD.S.R.IVdA.FRKFSRACKLLITLEPIADLELDK......Q-L.-E.YNI.NDLRLALYNNMAICQLKRKNFQHVV-t............
A0A158NBV8_ATTCE/134-217 ...s-AEEKYQVALRYKERSTELFKE.S.R.IIdA.FRRFSKACKLLITLEPIADLKLDK......Q--.LE.YNI.NNLRLALYNNMAICQLKRKNYQHVV-t............
A0A2P8YGL9_BLAGE/137-220 sdsk----KYKLALEHKIRGVELFKCgR.T.RD.A.FMRFSKALKLLITIMPLDLEYE--......CTY.PR.EEV.LSLRVILCNNIASCHLKYKNYDSVI-t............
W8BMD2_CERCA/129-213 ....NAAEIYALALRYKENGVAMFKQ.Y.P.IF.A.HDYFARAAKVLISYKPFENLSASS......DSV.SG.EAM.KLLFTQIQTNLAACLLSEERFEDVIY.............
A0A6P4E6H4_DRORH/127-211 ...d-AAEIYEVALRLKESGVATYKT.F.P.RF.S.FDYFVRAAKLLITYKPFNQLTKKA......NGI.NG.QEV.ETLFIQIQTNMAACLLQQKRYEHVIY.............
B4GEK7_DROPE/127-211 ....NAAEIYELALRFKESGVAMFKS.Y.P.KF.A.FDYFARAAKLLITYKPFDQLTKKS......NGI.NG.TTV.EALFVQLQTNLAACMLQEERYEHVIY.............
A0A6P8XL29_DROAB/124-208 ...t-ADEVFKLSLRYKDNGVVMFKP.H.P.KF.A.FDYFVRSAKLLITYKPFDKLEKKT......NGI.DG.IDV.EKLFVQVQTNLAACLLKEKRYEHVIY.............
A0A7E5WRK4_TRINI/130-213 .swe---RLYEAAVHHKERGVELFKQ.G.RaVD.A.FRRFNKALKMLIATEPLDPAVVSE......EVV.--.KDM.VNLKVKLYNNLAHCQLQFNEYDA---tlk..........
A0A0J7KC95_LASNI/130-213 ...n-TEEKYKIALRYKERGVELFKD.L.R.ITdA.FYKFSRACKILITLEPISDLELD-......NQL.E-.SNI.NDLRLALYNNMAMCHLSRKNYKHTI-a............
A0A7R8UQJ0_HERIL/93-177 ...t-VAEVYQLALQYKQNGVTMFKK.Y.P.KF.A.QEYFCRAAKCLISYQPFDVLTESS......EHV.NP.RDL.QSLFANLQTNIAACLVKEGRYEDVL-h............
E2B5K7_HARSA/130-213 ..sp--EEKYEVALKYKEIAVKLFKS.S.R.FVdA.FHKFSRACKILITLEPISDLELDK......H-L.-E.FNI.NNLRLTLYNNMARCQLNQKNFEHTV-a............
A0A6I8VBF3_DROPS/127-211 ....NAAEIYELALRFKESGVAMFKS.Y.P.KF.A.FDYFARAAKLLITYKPFDQLTKKS......NGI.NG.TTV.EALFVQLQTNLAACMLQEERYEHVIY.............
A0A6V7H010_9HYME/129-194 ..tp--EEKYSVALKYKEAGVGLFKE.G.RyVD.A.FHRFSKACKILITLEPIKDLELDK......T--.--.---.--------------------------leksnnvkalyrr
A0A182YGG5_ANOST/458-543 ..tv--GESLALAKQYKENGVKMFSQ.Y.P.LF.A.HTYFNQAAKCLLSWSPIDQLDPAI......EGA.ETvQEM.QTLLETLYLNIAACLIKQNRFEEVL-h............
A0A4S2KWH7_9HYME/460-543 ...s-AEEKYEVALRYKERGAELFKD.S.R.IVdA.FHKFSRACKLLITLEPIADLELDK......Q-L.-E.YNI.NDLRLALYNNMAICQLKRKNFQHVV-t............
Q9VDE4_DROME/127-211 ...s-AAEIYEVALRLKESGVATFKT.F.P.KF.A.FDYFVRAAKLLITYKPFDKLTKKT......NGI.NG.QAV.EELFIQIQTNLAACLLQEKRYEHVIY.............
A0A7M7MKI0_APIME/127-210 ..tp--EEKYNIALKYKETGVYLFKE.Q.R.WVdA.FYRFSRACKILITLEPIRDLELDK......EL-.-E.NNI.NNLRLVLYNNMAGCQLNRKNYEYTI-s............
A0A836EFD4_9HYME/135-218 ...s-AKEKYQIALRYKERGTELFKE.F.R.IIdA.FRRFSKACKLLITLEPIADLELDK......Q-L.-E.YNI.NNLRLALYNNMAICQLKRKNYQHVV-t............
A0A3B0KEE4_DROGU/127-211 ....NAAEIYELALRLKESGVAMFKS.Y.P.KF.A.FDYFARAAKLLITYKPFDQLTKKS......NGI.NG.TTV.EALFVQLQTNLAACMLQEERYEHVIY.............
A0A084W577_ANOSI/16-97 ..sf--TEMLELAKRYKENGVKMFPK.Y.P.LF.A.HAYFNRAVKCLLSWSPIEELEETS......AKE.EA.RSLvETLYL----NISACLIKENRYDEV--ph...........
A0A6I8T9V7_AEDAE/136-221 spke----NLCLAKKYKENGVKMFPK.Y.P.LF.A.HAYFNRAAKCLLSCEPLEALDPER......EGA.DTiSEM.QALLETLYLNISACLIKEQRFDDVL-q............
A0A026X140_OOCBI/48-133 ...s-AGEKYQVALRYKERGVELFRD.S.R.IVdA.FHEFSRACKILITLEPIPDPDLKL......EEQ.LE.SDI.KGLRLALYNNMAMCQLSRKNYEHVV-s............
T1GYE6_MEGSC/121-203 ...k-LKEIFELAKVYKANGVEMYKK.Y.P.KF.A.EDYFCKGAKLMLSCKPFDHLTEKD......DGV.EG.KDF.LNSFLIS--TITLQLIRDGKFEDVVY.............
A0A232FA50_9HYME/128-208 ...s-LEEKYQTALKYKEKGVELFKA.K.R.NVdA.FHRFSKACKTLITLEPIEETDETM......KNI.--.---.LTLKYVLYNNMAECQLIQENYDHTI-t............
A0A6P4JM59_DROKI/100-184 ...d-AAGMYDLALRLKESGVATFKS.Y.P.KF.A.FDYFARAAKLLITYKPFDKLTKRE......NGI.NG.STV.EELFIQIQTNLAACLLLEKRYEHVIY.............
A0A154P472_DUFNO/129-212 ..tp--EEKYRIALKYKEFGVVLFQQ.S.RwVD.A.FHKFSKACKILITLEPIYDLKLD-......KRL.EG.-DI.NNLRLVLYNNMAGCQLNRKNYEYTI-s............
#=GC seq_cons ...s.htEhYplAL+YKEpGVphFKp.h...hh.A.FchFu+AsKlLIThcPlscLchcp......ptl..t.psl.psLhltL.sNhAuC.LpcKpY-HVl.t............
//
