#=GF ID   Binary_toxB
#=GF AC   PF03495.18
#=GF DE   Clostridial binary toxin B/anthrax toxin PA Ca-binding domain
#=GF AU   Griffiths-Jones SR;0000-0001-6043-807X
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   ECOD
#=GF GA   25.00 10.00;
#=GF TC   25.10 10.00;
#=GF NC   24.80 9.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   AB_toxin
#=GF CL   CL0689
#=GF DR   INTERPRO; IPR035088;
#=GF DR   SCOP; 1acc; fa;
#=GF DR   TC; 1.C.42;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is a calcium binding domain in the anthrax toxin
#=GF CC   protective antigen.
#=GF SQ   45
#=GS A0A2V1H4L4_9GAMM/151-229    AC A0A2V1H4L4.1
#=GS A0A1F2P4M8_9EURY/63-138     AC A0A1F2P4M8.1
#=GS A0A0Q7Z7Y8_9ACTN/352-427    AC A0A0Q7Z7Y8.1
#=GS A0A1L8WHH5_9ENTE/209-285    AC A0A1L8WHH5.1
#=GS A0A3N0CFX7_9ACTN/695-771    AC A0A3N0CFX7.1
#=GS A0A5B9D6L9_9ARCH/1790-1857  AC A0A5B9D6L9.1
#=GS A0A2Z4LWU0_9FLAO/434-453    AC A0A2Z4LWU0.1
#=GS A0A7Y9H6C7_9ACTN/541-634    AC A0A7Y9H6C7.1
#=GS A0A2K9P208_9FIRM/1138-1181  AC A0A2K9P208.1
#=GS A0A1F2P477_9EURY/68-143     AC A0A1F2P477.1
#=GS A0A2R7YSR6_9ACTN/338-437    AC A0A2R7YSR6.1
#=GS A0A8J8MC89_9FIRM/57-133     AC A0A8J8MC89.1
#=GS A0A6H1A300_9ACTN/841-917    AC A0A6H1A300.1
#=GS A0A6L7EVC2_9ACTN/777-849    AC A0A6L7EVC2.1
#=GS A0A2V1H4L4_9GAMM/633-722    AC A0A2V1H4L4.1
#=GS A0A2Z4LWU0_9FLAO/518-540    AC A0A2Z4LWU0.1
#=GS A0A4Q2Y1G8_9BACT/228-298    AC A0A4Q2Y1G8.1
#=GS A0A1H9R5Q3_9CORY/94-150     AC A0A1H9R5Q3.1
#=GS A0A1I0G5Q4_9FIRM/738-812    AC A0A1I0G5Q4.1
#=GS A0A0Q8DZ07_9ACTN/907-982    AC A0A0Q8DZ07.1
#=GS A0A0Q8VHL5_9ACTN/62-137     AC A0A0Q8VHL5.1
#=GS A0A1V0E026_9CAUD/215-291    AC A0A1V0E026.1
#=GS PAG_BACAN/205-286           AC P13423.2
#=GS A0A1V0DG95_9BACT/22-95      AC A0A1V0DG95.1
#=GS A0A0Q5LNI1_9MICO/185-261    AC A0A0Q5LNI1.1
#=GS A0A075RCW8_BRELA/207-292    AC A0A075RCW8.1
#=GS A0A1S9AIP9_9BURK/103-126    AC A0A1S9AIP9.1
#=GS A0A037UMT5_SPIME/25-102     AC A0A037UMT5.1
#=GS A0A4Q2SIG4_9ACTN/364-394    AC A0A4Q2SIG4.1
#=GS A0A1E5LI66_9BACI/391-471    AC A0A1E5LI66.1
#=GS A0A562CHF3_9ACTN/357-432    AC A0A562CHF3.1
#=GS H3SHP6_9BACL/169-245        AC H3SHP6.1
#=GS A0A2K9P1Z8_9FIRM/857-900    AC A0A2K9P1Z8.1
#=GS A0A0Q8VHL5_9ACTN/17-91      AC A0A0Q8VHL5.1
#=GS V9W6R2_9BACL/16-51          AC V9W6R2.1
#=GS V9W533_9BACL/166-249        AC V9W533.1
#=GS A0A3N0CFX7_9ACTN/650-724    AC A0A3N0CFX7.1
#=GS A0A2Z4LWU0_9FLAO/546-565    AC A0A2Z4LWU0.1
#=GS H3SHP5_9BACL/175-251        AC H3SHP5.1
#=GS A0A1E5LI50_9BACI/402-479    AC A0A1E5LI50.1
#=GS A0A2T8FD87_9ACTN/674-748    AC A0A2T8FD87.1
#=GS A0A271J8M2_9BACT/19-95      AC A0A271J8M2.1
#=GS A0A1E5LI78_9BACI/365-442    AC A0A1E5LI78.1
#=GS R7XX34_9ACTN/413-487        AC R7XX34.1
#=GS A0A075R673_BRELA/207-292    AC A0A075R673.1
A0A2V1H4L4_9GAMM/151-229               ...........QDSDKDGLTD..EDER.N..VYFTD...................PDLKDTDKDGLSDGA......EVLSYKTSPVMPDTDGDSLNDWYEI....VnL.G.FDSELNNYNFNPLIA....................................
A0A1F2P4M8_9EURY/63-138                ..........l-DYNDDGLSNieEYER.K..ANPID...................RDVDDDRIDNLAERD......GLLGFVTDPFAKDTDGDGLDDLEEL....A.G.L.IDGMN----------esqmrw..............................
A0A0Q7Z7Y8_9ACTN/352-427               ..........v-DTDADGIRD..GLEV.R..GYVIR...................QKVIVSKTGPIRTY-......TIGTVRSDPRKKDTDADGVQDNAER....T.G.S.RNKRFNSHKSSP---vn..................................
A0A1L8WHH5_9ENTE/209-285               ..........v-DTDDDGIYD..EWEK.N..GYTVI...................NRIVTKWDDSYTSK-......GFTKYISNPNHAHTARDPYTDFEKV....I.G.D.VDEGMKWEARDPLVA....................................
A0A3N0CFX7_9ACTN/695-771               ..........a-DTDKDGLTD..KQEV.T..GSKIK...................QRVHRSKKNGGWYT-......-IGLRKTNPLVKDTDRDGLTDKQEI....T.G.S.ANKTKKAQ-------rksdptra............................
A0A5B9D6L9_9ARCH/1790-1857             ..........a-DSDDDGLGD..QEEI.N..TYFTD...................PNDTDTDDDGLSDGE......EINTHFTNPNDTDTDDDGLSDGEEI....N.T.H.F--------------tdpn................................
A0A2Z4LWU0_9FLAO/434-453               ...........MDTDGDGVPD..YIEI.N..G----...................---------------......-------------------------....-.-.-.---------------dpss................................
A0A7Y9H6C7_9ACTN/541-634               ...........KDTDKDGLSD..GKEV.K..GYKIK...................QRVKTRKGSF-----......VIGRTRSNPTKKDTDRDGLKDKVEV....T.G.K.ANKRYGKAKTDP---tkcdtdkggvsdgaevrakanpad............
A0A2K9P208_9FIRM/1138-1181             csngttidney----------..----.-..-----...................-------------VK......GYKNFIGNPNASNTLGDPYVDGINL....S.-.-.---------------agtht...............................
A0A1F2P477_9EURY/68-143                ..........l-DYNDDGLSNleEYER.K..ANPID...................RDVDDDGIDNLAEQE......GLLGFVTDPFAKDTDGDGLDDLEEL....A.G.Y.IDDMN----------esqmrw..............................
A0A2R7YSR6_9ACTN/338-437               ...........KDTDKDGLTD..GVEV.K..GFTIK...................QRVFITRSGKS---I......VIGKTRTNPTKADTDKDGLKDKVEK....T.G.K.ANKKFGKHKTDP---skcdtdrggvsdgkevkagsdpsqiksg........
A0A8J8MC89_9FIRM/57-133                ...........QDSDDDGISD..YLEL.N..GYMID..................nENNIVQWDGNGNKK-......---YHKSDPNSASTTGDPYDDRSKL....A.G.SgLHSPID---------piaknnpeva..........................
A0A6H1A300_9ACTN/841-917               ...........KDTDADGIND..GKEV.K..GYKIK...................QRVVTSKRGEPIKGY......RIGKVKSDPTKKDTDKDGLRDNQER....T.G.S.KNKRHDRHKSDP---vn..................................
A0A6L7EVC2_9ACTN/777-849               ..........a-DTDGDGLSD..STEL.K..GVRIK...................KQVVRAKGGSY----......VLRRLFSDPTKADTDGDKLGDRFEV....T.G.T.KNKRYGKRRTDPL--n...................................
A0A2V1H4L4_9GAMM/633-722               ..........v-DSDNDGLTD..KDEI.E..GWDIQifkdhdgecddtpvieglpAPICVPEPKKFENR-......---QVYSSPIKADTDEDGVTDFDEC....K.-.-.---------------rnrfdlgspqnase......................
A0A2Z4LWU0_9FLAO/518-540               ..........v-DTDGDGVPD..YTEI.N..G----...................---------------......-------------------------....-.-.-.---------------npatdpn.............................
A0A4Q2Y1G8_9BACT/228-298               ...........EDADHDGIED..AWETaN..GLNITl.................nDAAADPDSDGLSNLK......EYEA-QTNPQADDSDADGLKDGPEI....L.T.H.---------------fsnplv..............................
A0A1H9R5Q3_9CORY/94-150                ..........v-DTDGDGIPD..ELEI.A..GWTTA...................S--------------......-------------------------....-.-.-.---------------gevfrtdplladtdgdglsdgeeagnivegeeydti
A0A1I0G5Q4_9FIRM/738-812               ..........v-DSDKDGIPD..SIEL.-..GITKK...................MKLYNPYGKKYEYQ-......NVWTFSSNPAKKDTDGDNWNDSEDL....N.-.-.---------------pkrfdilltkktkhtl....................
A0A0Q8DZ07_9ACTN/907-982               ...........KDTDRDGLTD..AREV.V..GIAIN...................QVIVRSKAN--GGKY......TITTRKTNPTKKDTDGDGLTDKQEV....T.G.S.ANWRFKKRKSDP---tra.................................
A0A0Q8VHL5_9ACTN/62-137                ...........KDTDRDGLTD..RQEV.V..GVRIN...................QRVQRYKRDGGWY--......TITTRRSNPLKKDTDGDGLTDKQEV....T.G.S.ANRRFKMHRTDPTVA....................................
A0A1V0E026_9CAUD/215-291               ..........l-DTDNDNIPD..AYER.N..GYTIK...................DLIAVKWEDSFAEQ-......GYKKYVSNYLEPNTAGDPYTDYEKA....S.G.T.FDRAISKEARDPLVA....................................
PAG_BACAN/205-286                      ...........PDRDNDGIPD..SLEV.E..GYTVDvk...............nkRTFLSPWISNIHEKK......GLTKYKSSPEKWSTASDPYSDFEKV....T.G.R.IDKNVSPEARHPLVA....................................
A0A1V0DG95_9BACT/22-95                 ...........PDLDGDGIPN..VLEI.N..GYFYDvt...............rgLTACDPAVD------......-VPCFVTDYQQWSTDGDPFSDFDEI....S.-.Q.ANLPIAAPYSHPLVA....................................
A0A0Q5LNI1_9MICO/185-261               ..........g-DRDHDLVPD..DLER.G..GYALV...................DSSLVPWRDDLAAR-......GHTKYLSDPNHCRSARDPYTDLEKV....S.A.M.MPGGTRTEARDPLVA....................................
A0A075RCW8_BRELA/207-292               ...........EDSDGDGIPD..SLEV.E..GYTLDvk...............nkKLILMPWIEKVHGKKrtksgaPLTKYKSSPLKWSTASDPYSDFAKV....S.G.M.IDKQV--QVRNPLLA....................................
A0A1S9AIP9_9BURK/103-126               ..........h-DRDRDGIPD..RYER.H..GYA--...................---------------......-------------------------....-.-.-.---------------spyags..............................
A0A037UMT5_SPIME/25-102                ..........l-DSDDDGIPD..CWEI.N..GYTVE...................KGLIVPWDDKKHKPG......KFIKYKSDPYNSHTTGDPYSDAEKV....L.G.K.IDQGVLPEAHHPLVA....................................
A0A4Q2SIG4_9ACTN/364-394               ..........r-DTDGDGIGD..QREA.S..GYRLR...................D--------------......-------------------------....-.-.-.---------------grsvrsdpge..........................
A0A1E5LI66_9BACI/391-471               ...........QDADGDNIYD..VWEK.E..GYTYV..................lGAGIVKWDDKDADNYg....eGAIKYVTSPFSRSTDEDPYSDYEEV....T.G.Q.VDKGIAAIAQHPLV-p...................................
A0A562CHF3_9ACTN/357-432               ...........KDTDRDGLTD..RQEI.R..GINVN...................QYA---WRSKANGGR.....yKIGLRKSNPLVKDTDRDGLTDRQEV....T.G.S.ANRKFGKRRSDPTVA....................................
H3SHP6_9BACL/169-245                   ..........l-DTDNDGIYD..EWEI.N..GYTVI...................NHLVVPWDEKYAAQ-......GYKKYVSNPNESHTAGDPYSDLEKA....S.G.S.IDRNIKKVAWDPLIA....................................
A0A2K9P1Z8_9FIRM/857-900               csngttidney----------..----.-..-----...................-------------VK......GYKNFIGNPNASNTLGDPYVDGINL....S.-.-.---------------agtht...............................
A0A0Q8VHL5_9ACTN/17-91                 ..........r-DTDGDGLVD..GPEA.K..GITIR...................QVVFTNVGRPRRGK-......AIGTVRTNPCAKDTDRDGLTDRQEV....V.GvR.INQRVQRYKR-----dg..................................
V9W6R2_9BACL/16-51                     ..........m-DTDDDGIYD..SWER.E..GYTVI...................NRVVVKWDQEKHKP-......-------------------------....-.-.-.---------------pe..................................
V9W533_9BACL/166-249                   ..........l-DTDDDGIYD..DWEV.N..GYYIK...................NHLVLPWPKKGSEEEkelikqGFKKFVSNPNESHTAGDPYSDLEKA....S.G.A.FDRTIHKAARDPLVA....................................
A0A3N0CFX7_9ACTN/650-724               ...........KDSDGDGLGD..GAEV.K..GITIN...................QVVTTLAGRPRAGK-......KIGLVSTNPCAADTDKDGLTDKQEV....T.GsK.IKQRVHRSK------kng.................................
A0A2Z4LWU0_9FLAO/546-565               ..........v-DTDGDGVPD..YVEI.N..G----...................---------------......-------------------------....-.-.-.---------------epss................................
H3SHP5_9BACL/175-251                   ..........i-DTDKDGIYD..EWEI.N..GYTVI...................NNVAVPWNEKYAAQ-......GYKKYVSNPNESHTAGDPYTDLEKA....S.G.R.IDRNIHKVAWDPLVA....................................
A0A1E5LI50_9BACI/402-479               ..........v-DTDNDGIVD..EWEM.E..GYTYI..................pGLGLVLWDDEFTDF-......GVQKYITSPFSRSTDEDPYSDYEEV....T.G.Q.VDRAIASLATHPLV-p...................................
A0A2T8FD87_9ACTN/674-748               ..........r-DTDKDGLTD..GLEV.K..GYKIK...................QVVYITRSG---SKI......TIGKTRSNPTKADTDKDRLKDKVEK....T.G.K.ANKRYQKRKTDP---tkc.................................
A0A271J8M2_9BACT/19-95                 ...........QDSDGDGVPN..ALEA.S..GFRFD...................IGSGAPVACDPAIE-......-LPCYVTDPLTWSSDGDPYSDLQEA....S.GvN.MDATVEAPYNSPLVA....................................
A0A1E5LI78_9BACI/365-442               ..........l-DSDSDGIPN..TWEI.N..GYTFS..................pLIGLMEWDDEFLTE-......ELEKYVTSPLRFSTDGDPYSDYEEV....T.R.Q.VDGAISTVATHPLV-p...................................
R7XX34_9ACTN/413-487                   ...........KDTDGDKIND..RVEA.K..GYRIK...................QRVVVKRNGKTVN--......-IGRVRSNPAKADTDRDKLTDGDER....T.G.R.RNKKWKRRKTSPML-c...................................
A0A075R673_BRELA/207-292               ...........EDSDGDGIPD..SLEI.E..GYTLDvk...............nkKLILMPWIEKVHGKKrtksgaPLTKYTSSPMKWSTASDPYSDFAKV....S.G.M.IDKKV--KVKHPLIA....................................
#=GC seq_cons                          ..........h.DoDsDGlsD..thEl.p..Gaplp...................phhhh.htsthtt........thtphhosP.ptsTstDshsDhpcl....o.G.p.hsttht..h..........................................
//