#=GF ID Bunya_NS-S_2
#=GF AC PF03231.17
#=GF DE Bunyavirus non-structural protein NS-S
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Pfam-B_3018 (release 6.5)
#=GF GA 25.00 25.00;
#=GF TC 165.60 165.30;
#=GF NC 20.70 18.50;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF DR INTERPRO; IPR004915;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family represents the Bunyavirus NS-S family. Bunyavirus
#=GF CC has three genomic segments: small (S), middle-sized (M), and
#=GF CC large (L). The S segment encodes the nucleocapsid and a
#=GF CC non-structural protein. The M segment codes for two
#=GF CC glycoproteins, G1 and G2, and another non-structural protein
#=GF CC (NSm). The L segment codes for an RNA polymerase.
#=GF SQ 9
#=GS F5B5X9_9VIRU/1-433 AC F5B5X9.1
#=GS Q84402_9VIRU/1-437 AC Q84402.1
#=GS Q9YUD6_9VIRU/1-471 AC Q9YUD6.1
#=GS Q5G1B3_9VIRU/1-438 AC Q5G1B3.1
#=GS P89253_WASMV/1-437 AC P89253.1
#=GS NSS_TSWV1/1-430 AC P26002.1
#=GS A0A1S5WKM1_9VIRU/1-431 AC A0A1S5WKM1.1
#=GS I3PCT0_9VIRU/2-438 AC I3PCT0.1
#=GS A0A059TY21_9VIRU/1-440 AC A0A059TY21.1
F5B5X9_9VIRU/1-433 ......MSSGVYE................SIIQTKASVWGSTASGKSIVDSYWI...YEfPTGSPLVQ...TQLYSDSRSKSSFGY--TSKIGDIPAVEEEILSQNVHIPVFDD...IDFSININDSFLAISVCSNTVNTNGVKHQGHLKVLSL--AQLHPFEPVMSRSEIASRFRLQEEDIIPDDKYISAANKGSLSCVKEHTYKVEMSHNQALGKV...NVLSPNRNVHEWLYSFKPNF--NQIESNNRTVNSLAVKSLLMATENNIMPN..SQAFVKASTDSHFKLSLWLRI--PKVLKQIAIQKLFKFAGDETGKSFYLSIACIPNHNSVETAL..NVTVICKHQL.PIPKSKAPF...ELSMIFSD......LKEPYNTVH.----....DPS.YPQRIVHAL.LETHTSFAQVLCNKLQEDVIIYTINS.PELTPAKLDLGERTLNYSEDASKKKYFLSKTLE.....CLPVNVQTMSYLDSIQIPSWKIDFARGEIRIS.
Q84402_9VIRU/1-437 ......MSTARSA................--ASEFVKSYGTR-DNRAINDCYSV...FS.GEGVNFLN...LFMHNNAGIKSAFSINDLGRNEDIKIHEAEVIDSCHDYHYFEK...FGLDIIFCEHEMSLVVGKPGVKNTGCKFTMHNQIFNPNSDTLALTPGTVSENEFYEKIKIRSNGLLPSGWYQDECCKNNFYIATNGDLTLDYGF-SVMGKT...TSYWRESISREKILSVKQKCLPDNTVPTNRLLSTSTVKGIQLG--SELAPD..TTVILSLKQNLNVDLKSQYRVSFHGIQEEGAFARTFCVPFENKSRMICLYAKTVVDNSNERTTL..IIKVVTKTIE.SHLVIPI-R...NHINCVKK......IGARIGLVD.SIES....DPN.YNQMIVKEL.LGVHTQFAINLSLVIKKPIIVFKMYD.IELNNNHIDVYGRILNYQTDAEGNAYFLSKTLE.....VLPKSLSTLSYLGSIAPIQWEESLEHQHFIVK.
Q9YUD6_9VIRU/1-471 ......MSTESSNpgstenvalipepfdeQYCEEALTSYGNNLDKSALVDVYSM...FE.-DDKLVFQ...SIHATNGRFKATCAFGHSDMVLDSEQELKTSISSEIFHQEFDAisgINSIISLQGENIHVIISHPEQKVKSYKYAFHGRIASN-DVFPRISGF----DEFRSQYSCNPYKFVYNPGMLGLESETNTVIFPVEKLGTLPAHASAFGNNfdrCHFSGSSVPGFMTVKAVSESSKRTQEKAHRQLHNKSLKALEIVSNSDFRSTyiTKTTLKARKNGMMTIQVQVKISTASLKREHLIA----IPDDPLKRLVYCSSECLGQTSPGLSTF..IFEVMCLDCLvDRVTPDVTYfagALSTCFTDepphilLKARSGILSsLADS....DRDkINEIICKNL.VSVHLGLATDLAKKLNKPINVFTIKDtSSMTTDMVEVDGKKYRVLKDSNGDYYFTSATFEktligAYKSCQTFVDYCDNK-----KLSINGDNVFIF.
Q5G1B3_9VIRU/1-438 ......MSTAKMS................--AVEFSKTYGTK-DSRSVNDCYSV...YS.GTGINFLN...LFMHTNTGIKSAFSVNDLARNEDVKIHEAEVINSLHSYNYFEK...FGLDIILCSHIMDIIVTKPNVKNTGCKFQMHNQIFNPNEDTLAKTPGVISEEDFYEISKIKLKGLTPFGWYVDECKKHDFYISNSGDISLDYGF-PVMGKT...TSYWRENLPREKIISVKQKCVPNVSALTNRILPLPTVKAIQIA--SELASE..KTVVLASRQRLDIDVKSQYRVSFPGIQDEGAFTRTFCIPMDNTARIICFYAKTSVDSSNERTTL..TIKIVNKTIE.NNCPGPIPK...DHIYCDKS......IGARIGLVD.VVRG....DPN.YNLMIAREM.VSVHTNFALKLSESLKKPVIVFKMYD.KELNFETYDLSGRSLSYQKDSSGNIYFLSKTLE.....ILPKSLSTLTYLKSISPACWKESISMQHFYV-g
P89253_WASMV/1-437 ......MSTAKNA................--ASEFIKSYGTR-DNRAVNDCYSV...FT.GEGVNFLN...LFMHNNAGIKSAFSINDLGRNEDVKIHEAEVVDSCHDYHYFEK...FGLDITFCEHEMNLIVRKPGVKNTGCKFTMHNQIFNPNSNILNMTPGTISEDAFYDRSKIASSGLLPSGWCLDECYKNNFYIATNGDLTLDYGF-SVMGKT...TSYWRESMSREKILSVKQKCFFDNTVPTNRLLSTSIVKGIQIG--SELASD..TTVILSCKQNLNIDLKSQYRISFHGIQEEGAFARTFCVPFENKSRMISFYAKTVADNSNERTTL..IIKVVTKTVD.SHLVIPI-R...NHVNCEMK......IGARVGLVD.FCDS....DPN.YNQLIVKNL.LSVHTQFTINLSEVIQKPVIVFKMYD.KELHNDYTEVSGRILNYQVDSEGNIYFLSKTLE.....VLPKSLSTLSYLGSIAPIQWKECLEHQHFVVK.
NSS_TSWV1/1-430 ......MSSSVYE................SIIQTRASVWGSTASGKAVVDSYWI...HElGTGSQLVQ...TQLYSDSRSKVVLWL--YCKVGIFPVKKKRFLSQHVYIPIFDD...IDFSINIDNSVLALSVCSNTVNANGVKHQGHLKVLSP--AQLHSIESIMNRSDITDRFQLQEKDIIPNDKYIEAANKGSLSCVKEHTYKIEMCYNQALGKV...NVLSPNRNVHEWLYSFKPNF--NQVESNNRTVNSLAVKSLLMSAENNIMPN..SQ----ASTDSHFKLSLWLRV--PKVLKQVSIQKLFKVAGDETNKTFYLSIACIPNHNSVETAL..NITVICKHQL.PIRKCKAPF...ELSMMFSD......LKEPYNIVH.----....DPS.YPKGSVPMLwLETHTSLHKFFATNLQEDVIIYTLNN.LELTPGKLDLGERTLNYSEDAYKRKYFLSKTLE.....CLPSNTQTMSYLDSIQIPSWKIDFARGEIKIS.
A0A1S5WKM1_9VIRU/1-431 ......MSSSCLD................SIVQSKASVWGTSVSGKSILDTYWI...HDyETGKPLLE...TQLYSDSRSKSSFCY--TNKVDDIPIADAELVSDASVFSLLDD...IDFSMTIEESFITVSVCSNTVNTNGVKHQGHLKIIST--QKPVALNFLAESDHILKRFNLKETDIVPEDRFIAAANRGSLSCVKEIMYETKTSNNQAYGKV...NVLSPNRNSNEWIYTVKPMF--NQTETNNRTVNSLAIKSLLLSAVNDISPC..SQVFLKAFTDKSFKLSFWLRI--PKVLKHTDFYKCFKIPNGSSN--LSLTINCIPNYNNIETAL..NFSLVSLKLK.EPLSAPKQG...KFVINFSS......LKEPCCNVF.----....DLT.YPQRIVHSL.LEVHTSLAKKLSDFLREEVIIYTLNL.PETEVKKLDLAGRTLNYNESPSGKKYFLSQTLN.....CLPKNSQSLAYLNSFQFCSLHVDYIRGEICV-l
I3PCT0_9VIRU/2-438 qtlvnl-------................------GKEFGSQVNQKHVIDTYWVktkFS.--GSNNFGsnyVQMYSDEDIQTGFRFNEPGMEII--SDVPDVLQKDSSVEVFSD...LGVSFVFDAEKVTIKISHGSVNKLGVKHKGHLKVLEF--EDPNVIEGTVDRNLVASVPGINNDDIEIKNETINALPSMNMIHLKEDSYKITKSPNCFFGKR...NMLRRGWIGTGYVTNIHPIG-YVLPKATNRCLGTLSLKSMESTVEKGVLSSdiAHAELSLGGKCNFHLFS----SCKGDLGDVSFMRNVKFFEDKHERVFTIYVKTSSDIDNNKSSIlvIFKTVCYSES.KEGTVSVS-...----SDDK......LQGSINLSE.LPESgffdHKA.KSMLIVQSL.IKIHNEFASKISEKLNKSVIVYTLRSvDSFKKEITEIDSRAMNYLISPEGEVFFLSRTFQ....eSLPTNMSSLTYFFDLQTFGWSANYLSGDLVV-r
A0A059TY21_9VIRU/1-440 ......MSTVKTT................--AVDFFLNYGISSDSRSSNDCYRI...FS.GIGDPIMD...IFMHSTIGIKPAFSISGLGKNEDIKAHEAEVIEEHHNYDVFNR...FGLDINFCNHFLEITVKKPSVKNYETKFQMHNQIFQPSRRLINHGMGKISENDFFALTDIAKENIYPRDWFINEAERKTFFMADIAGFSLDYGF-SVMGKT...TSYWRENLEKTSLISIKQKSAGNPVVPTNRLLSAGTIKAVEIA--SAIASD..KTTILAVKQDLDADLRTQFRISLPGEYNEAGLARTFLINQGSKGQYICIYARTSLDRPNERTTL..IIKVVTQKRPgDYDMMMLPR...DHANCRKL......VGASFGTVE.RKLT....DPN.YNKIIAHEM.LAVHTSFALKISKILSKPVIVYKVYE.KELSPKAVEVDGRTFNYNEDVDGNVYFLSKTLE.....MLPISLSVLVYLDSAAPPCWKEHRGLGHFTVE.
#=GC seq_cons ......MSoup.s..................spphspsaGop.ss+ulsDsY.l...as.spGsshlp...h.haosuthKouFuhsthu+stDl.hc-sEllspppsaphF-c...hshsIshsschlslhVs+ssVpssGsKaphH.pIhss..splshh.uhhscs-hhsphplpppsllPpshalstss+sshhhspptshpl-hua.sshGKs...ssh.tpphs+EhlhSlK.ps..spstssNRhLsohslKulplu..ssltss..opshLpsppchshcLps.hRlShsulhc-suht+sFplst-sps+hlslhscslsspsNtcToL..hlcVVspph..shhssslsh...phs.shpc......ltuphslVc....s....DPs.YsphIV+pL.LpVHTsFAhpLSchLpKsVIVaplhs..ELssctl-lsGRsLNYpcDupGphYFLSKTLE.....sLPpshooLoYLsSlt..sWK.shtpschhV..
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