#=GF ID   CAA3_Cox_suIV
#=GF AC   PF20814.1
#=GF DE   CAA3-type cytochrome c oxidase subunit IV
#=GF AU   Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   ECOD:3393.1.1
#=GF GA   27.50 27.50;
#=GF TC   27.50 98.40;
#=GF NC   25.90 22.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RC   Paper describing PDB structure 2yev
#=GF RN   [1]
#=GF RM   22763450
#=GF RT   Structural insights into electron transfer in caa3-type
#=GF RT   cytochrome oxidase.
#=GF RA   Lyons JA, Aragao D, Slattery O, Pisliakov AV, Soulimane T,
#=GF RA   Caffrey M;
#=GF RL   Nature. 2012;487:514-518.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Cytochrome c oxidase plays a key role in the respiratory chain
#=GF CC   of mitochondria and aerobic prokaryotes. This electron transfer
#=GF CC   complex consists of three subunits, SU I/III, IIc and IV, which
#=GF CC   together form a bundle of 23 transmembrane (TM) helices and a
#=GF CC   bulky extra-membrane cytochrome c/cupredoxin domain. This family
#=GF CC   represents subunit IV, which shows two connected TM helices [1].
#=GF CC   It is predominantly found in Deinococcus-Thermus.
#=GF SQ   8
#=GS A0A399EHJ5_9DEIN/1-64  AC A0A399EHJ5.1
#=GS A0A399EZ17_9DEIN/4-67  AC A0A399EZ17.1
#=GS F2NNB9_MARHT/4-67      AC F2NNB9.1
#=GS A0A399FAL7_9DEIN/4-67  AC A0A399FAL7.1
#=GS Q5SH67_THET8/1-64      AC Q5SH67.1
#=GS E4U6L8_OCEP5/4-67      AC E4U6L8.1
#=GS A0A0X8D6U2_9DEIN/1-64  AC A0A0X8D6U2.1
#=GS D7BBW9_MEISD/10-73     AC D7BBW9.1
A0A399EHJ5_9DEIN/1-64             ..MLFAIIFTVLSVAITWLLYLALRPRTLEVESETADLRYIAMALVLIVLTAAAVASMLILGKLGQ.
A0A399EZ17_9DEIN/4-67             .a-VFTLIFVIGSILVTSLIYLAINPRSVNVEGEGADLRYIGFALVLIILSAATIGAMLMLGKAHN.
F2NNB9_MARHT/4-67                 ..VWYVTLFFIGSLVVGYVLYVALSPRSVAVEGENVDLRFIGFVLALIILAAFTISAMLILGKID-e
A0A399FAL7_9DEIN/4-67             wt--LAILFTIGVVLVTTLLYLALRPRSVEYEGEGADLRFIGFALLLIILTAATILVMLLLGRVGQ.
Q5SH67_THET8/1-64                 ..MVYIALFALGAALVTLFFYLILNPRVLTTEGETFDLRFVLFMLLLILLAAGTVALMLLIGKAHH.
E4U6L8_OCEP5/4-67                 .l-IYVAVFVVGALVVTGVFYLTFNPRMLATESGEVDLVLIGRTLLMIVLTSVAVAAMLMLGRYY-v
A0A0X8D6U2_9DEIN/1-64             ..MVYIALFALGAALVTLFFYLILNPRVLTTEGETFDLRFVLFMLLLILLAAGTVALMLLIGKAYH.
D7BBW9_MEISD/10-73                .y-LLAALFTIGAVLVTTLIYLAINPRSVATKSESADLRYIGFALLLIILSAGTIASLLYLGKLG-l
#=GC seq_cons                     ...lassLFslGulLVThllYLALNPRolssEGEssDLRaIGFsLLLIlLoAuTlAuMLlLGKhtp.
//