#=GF ID CAMP_factor
#=GF AC PF07373.15
#=GF DE CAMP factor (Cfa)
#=GF AU Moxon SJ;0000-0003-4644-1816
#=GF SE Pfam-B_20762 (release 10.0)
#=GF GA 23.30 23.30;
#=GF TC 23.40 37.40;
#=GF NC 22.70 21.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 10456923
#=GF RT Identification, cloning, and expression of the CAMP factor gene
#=GF RT (cfa) of group A streptococci.
#=GF RA Gase K, Ferretti JJ, Primeaux C, McShan WM;
#=GF RL Infect Immun 1999;67:4725-4731.
#=GF DR INTERPRO; IPR010860;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family consists of several bacterial CAMP factor (Cfa)
#=GF CC proteins which seem to be specific to Streptococcus species. The
#=GF CC CAMP reaction is a synergistic lysis of erythrocytes by the
#=GF CC interaction of an extracellular protein (CAMP factor) produced
#=GF CC by some streptococcal species with the Staphylococcus aureus
#=GF CC sphingomyelinase C (beta-toxin) [1].
#=GF SQ 58
#=GS W4TRM1_CUTAC/53-273 AC W4TRM1.1
#=GS G4CW01_9ACTN/36-259 AC G4CW01.1
#=GS A0A2U1E1K3_9FIRM/36-259 AC A0A2U1E1K3.1
#=GS A0A2U1E1R8_9FIRM/39-254 AC A0A2U1E1R8.1
#=GS D6ZJ92_MOBCV/126-344 AC D6ZJ92.1
#=GS A0A2I1M523_9FIRM/42-257 AC A0A2I1M523.1
#=GS A0A242KD20_9ENTE/16-238 AC A0A242KD20.1
#=GS Q99ZD8_STRP1/39-255 AC Q99ZD8.2
#=GS A0A239VLE7_9MICO/49-266 AC A0A239VLE7.1
#=GS A0A1G7PCM6_9LACT/268-483 AC A0A1G7PCM6.1
#=GS A0A1H9KS33_9LACT/31-249 AC A0A1H9KS33.1
#=GS W4TRR5_CUTAC/1-48 AC W4TRR5.1
#=GS A0A1G7PCM6_9LACT/33-256 AC A0A1G7PCM6.1
#=GS A0A1W1Y2P2_9LACT/613-691 AC A0A1W1Y2P2.1
#=GS K0YSY3_9ACTO/38-256 AC K0YSY3.1
#=GS W4U2Z0_CUTAC/7-227 AC W4U2Z0.1
#=GS A0A2I1MBT0_9FIRM/36-253 AC A0A2I1MBT0.1
#=GS A0A4Q9UZ93_9ACTO/42-259 AC A0A4Q9UZ93.1
#=GS M4QUU4_STRIN/39-255 AC M4QUU4.1
#=GS W4UC12_CUTAC/1-145 AC W4UC12.1
#=GS W4TNS0_CUTAC/40-173 AC W4TNS0.1
#=GS B0S2D6_FINM2/45-263 AC B0S2D6.1
#=GS D7BMD1_ARCHD/50-269 AC D7BMD1.1
#=GS Q8CX01_STRA5/39-254 AC Q8CX01.1
#=GS G4CZ87_9ACTN/34-255 AC G4CZ87.1
#=GS W4UF19_CUTAC/1-155 AC W4UF19.1
#=GS W4UF60_CUTAC/41-157 AC W4UF60.1
#=GS K0YSC1_9ACTO/128-346 AC K0YSC1.1
#=GS G5KDX6_9STRE/35-251 AC G5KDX6.1
#=GS A0A1V4KWX6_PATFA/24-104 AC A0A1V4KWX6.1
#=GS A0A1G7PCM6_9LACT/500-714 AC A0A1G7PCM6.1
#=GS W4U0R1_CUTAC/41-169 AC W4U0R1.1
#=GS W4UFP1_CUTAC/43-263 AC W4UFP1.1
#=GS W4TLA0_CUTAC/80-300 AC W4TLA0.1
#=GS B0S2D5_FINM2/35-257 AC B0S2D5.1
#=GS W4U884_CUTAC/1-90 AC W4U884.1
#=GS A0A1W1Y2P2_9LACT/692-773 AC A0A1W1Y2P2.1
#=GS A0A2I1MBV7_9FIRM/55-283 AC A0A2I1MBV7.1
#=GS W4TXR1_CUTAC/7-227 AC W4TXR1.1
#=GS A0A0X8FC58_9LACT/649-754 AC A0A0X8FC58.1
#=GS A0A0X8FC58_9LACT/404-588 AC A0A0X8FC58.1
#=GS W4TIT7_CUTAC/43-263 AC W4TIT7.1
#=GS A0A2I1MBP9_9FIRM/107-277 AC A0A2I1MBP9.1
#=GS E0QPF2_9ACTO/43-261 AC E0QPF2.1
#=GS W4U4F8_CUTAC/1-119 AC W4U4F8.1
#=GS W4U2E0_CUTAC/19-219 AC W4U2E0.1
#=GS G5KGP4_9STRE/33-250 AC G5KGP4.1
#=GS W4TYX4_CUTAC/12-235 AC W4TYX4.1
#=GS A0A2I1M9L2_9FIRM/43-244 AC A0A2I1M9L2.1
#=GS A0A371IP17_9FIRM/39-260 AC A0A371IP17.1
#=GS W4UFZ3_CUTAC/20-240 AC W4UFZ3.1
#=GS U1FCU7_9ACTN/37-256 AC U1FCU7.1
#=GS W4U6H3_CUTAC/36-149 AC W4U6H3.1
#=GS A0A1W1Y2P2_9LACT/422-607 AC A0A1W1Y2P2.1
#=GS A0A1H8EX60_9FIRM/1-144 AC A0A1H8EX60.1
#=GS W4TNF4_CUTAC/3-199 AC W4TNF4.1
#=GS A0A0X8FC58_9LACT/595-676 AC A0A0X8FC58.1
#=GS A0A2I1MBP3_9FIRM/71-208 AC A0A2I1MBP3.1
W4TRM1_CUTAC/53-273 .....................avssntadahkllegvngritslndd----------------------LKV....A......K.....A..SLSP....M....E....V.IDT.....IADLLKQAK.Q..LKAQ..L..E...KIVK....GV...VTFA--KSIPARVELFLAMCDTTHTATLTFQDKVQNAHSTVFLAIAHAINVLITINSTPAQLTDEVAALKKAIAAAQAMPDLKPTDVATKYVRAKLGRLMVQVR.FDRNTCVINYKDRDA..VRLLNRAIIRAGQVRSNAWVR...VADVDQAIK.ELKAAYQDAL.......................................................
G4CW01_9ACTN/36-259 ............................................arq---HTQVDAEQALAQVNARIAELQK....M.....hQaqvpaS..DAPK....T....N....Y.GEE.....IRKLLDTAF.E..LRTT..I..E...SIIA....GK...VPPVDLSTIPARVDLLTTSVKTIQQANHDLVNKVEAAHVELGFSITRALIRTINPTSTAAQLAESKADVLATYAKVAAYPDLKPTDTATVYVKDRLNKKIWQTR.INRDKYLL-GKNAEG..YKAINKALTHATGVWFNPAAT...VQQVDDEVK.ALDLAFQAAL.......................................................
A0A2U1E1K3_9FIRM/36-259 ...............................vedeltindleiykrk---------------VQAVKSEAKQ....L.....tP.....H..NKEN....V....KmlnnF.DEK.....TDELEVGIE.K..SFEA..Q..G...MAGL....GF...AQIYDLSSIPQRLMLIGRLCVAMRFATTALRYKVDQAHVEIAEYVFQGLVIAVSPFHTVDDMKAYMAEFEALKAKLIGYPDLTQNDTANLYVRSDLDAKLHKAR.FLYMNDLKEAPD-YV..LDELNKVIREVTRIRLQPQRT...VAEIYQAQD.MLDAAVGKAY.......................................................
A0A2U1E1R8_9FIRM/39-254 .........................................levsdl------------KSDIKTAVASVQD....I.....tP.....S..NDDE....K....D....I.LDK.....YHEAARSVNrE..LEIS..E..E...RVSG....AVgigDSIYDLTTIPVRIQLLIRIGRAIRFATTELSNKVVAAHTKITEYILTGILYVLNPFASEGQIMEYIERFEPLQQELLAYPDLRPEDIATIYKKAAFSRELSEARrVINSTNKLT-RQFKA..-RALNEAIKEGQRMWWRLDVT...CGELDAQIE.KVH-------klmeai.................................................
D6ZJ92_MOBCV/126-344 ...............................................STELTPSEAQSAIDDINAAVETLKE....I......Q.....S..EEPK....A....D....W.SKE.....FDKLFATAT.E..LTQS..L..A...VVAG....GY...QTLANPDLIMARTHLIVEIGLTVDKSANNLRYKIQKAHVELGFSVTRAIMRVANIGATVYQLNDSISDLRATYERVSTYRDLKSTDTATIYVKDLLNKAIWNTR.VARDKEILTHKNFRT..YQTLNKEITKAVRVWFKAKAT...VAECDAAIA.KLNTAYATAY.......................................................
A0A2I1M523_9FIRM/42-257 ..........................................eektp-----QKEAEEKINYLQEIISSLEN....I......S.....GglAGNQ....L....S....W.LKE.....LKHAAEFLG.K..IVNK..G..I...G---....--...SAAELRNKIIPRVDLLINVAETITADATELADSEQQAHVIIGFSVTRALLKATDLFEGAEGLNKASENLSASLDKAREVPKLTDDSKRTHYTLEKLDRAIAKAK.EIRNKELKNKLDPSK..LADIDLLIRQAQDVRRDGRAT...VGEVNAMAA.ELNEKIDEAY.......................................................
A0A242KD20_9ENTE/16-238 ..........................................ayaqt-----QEISQSTTTAVQNEKAKLDE....L......E.....E..KVAG....T....A....F.EEA.....FNQLVPVLN.T..LEKD..L..T...ASSSnarfNP...VTIYDLDSIGVRLQLITEISNAIAFSVEQLDNKVEQAHRELGVEITKAVIAVADPFASVSKLEQQIISLKQLMEKVLTYPDLDLDAKATHVVKQKLDAAIWATR.FERDKKVLGKVPFAV..YNDLNKVITKAVGVQLSLKST...VRDVNTAIA.NLEKALATA-i......................................................
Q99ZD8_STRP1/39-255 .........................................mnnnqa-----NFQRDALVQKLDEGHQQLEA....I......K.....H..EAKG....T....D....I.ETT.....VNKAIDAVD.H..MKSS..I..R...F---....NT...ETIYDFSSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKAQVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTR.LERDKKVLGIKPFDV..YNRLNKAITHAVGVQLNPTTT...VQQVDDEVI.AVQDALETAL.......................................................
A0A239VLE7_9MICO/49-266 ...........................................iaay-----RAEAKNDLNKINNSINELQT....A......K.....E..IAPD....T....N....Y.LKE.....IKQLLKTAF.E..LRGT..I..V...AIAS....GQ...PPAFDPATIKARVEVVRQIAVTIHYSHKNLRNKISKAHAELGFAVTKAIIRVCNPTSTMEQLNASRDELIQDLEKVKNYPDLKPTDRATIYVKAGLNRKIWEIR.WGRDTKILGKAERGV..YKELNKNITHAVGVWAKINVT...VADVDKEIA.ALDAAYKKAL.......................................................
A0A1G7PCM6_9LACT/268-483 ....................................rvadhkddllv---------------IKDKEEQIKH....L......K.....E..VLAG....T....N....Y.ESI.....IERASKLVE.N..IKKEatL..E...ASVA....GK...VPL-KVDTIGSRIEALVTIIDGIVYATTEATNKVSDAHKDMGYTITKALITLADPFSSQASIDHQVQQILDLKEGIKNYPDLTEDDIATIYVKAKLDNAIWNTR.FIRDKNILGKVPFEQ..YNDLNKTITKAVGVQLDPKST...VKDINSSVQ.QLQEKLQS--il.....................................................
A0A1H9KS33_9LACT/31-249 .........................................pvyvnd---------QNLEAKITEDAQKLAE....L......K.....D..AVKG....T....Q....Y.ENM.....TNSAIAALE.K..LKVQ..N..EtdpTLKF....NP...ETIYDLDSLGARIEALADVIDAINFASNELSGKVEAAHREMGFAITKLVIRIADPFSSVESIKNQVAVVNDLKEKLVNYADLDPNSRATVYAKAKLRKAIWNTR.FERDQKILGVKNFKT..YNNLNKVITKAVGIQLRRTTT...VQDVDNAVL.MLQDAMEFAL.......................................................
W4TRR5_CUTAC/1-48 ..............................................m-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...--------------------------------------------------------------------------------------------------------.--------AKKDQAV..VDTLNKEISKADKVRANAKST...VAQVDTAVD.QLRAAYQTAL.......................................................
A0A1G7PCM6_9LACT/33-256 ........................................ntsqayn------ENVQGIALEIVNQKEKLEE....L......E.....H..TVLG....T....P....Y.EDL.....LNKSFDILE.T..VISD..A..T...AIAKgegiNP...ETIYALNSIGPRLTAITEVIEAIDYSVNHLNNKIIDAHHMMGLKITHLTYTLLNPLSSNASIEKLIAELRETKRKAASLPDLSEKDTATIYSKAKLDKAIWNTR.FIRDEKILGKMDADV..YHSLNRAITKAVGIQLDPKST...VGEIDQAVA.EIESQLKQAL.......................................................
A0A1W1Y2P2_9LACT/613-691 ........................................ipkeeqi-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...---------------------------------------------------------------------------------------ASNQLKRDLKDLIWQTR.FDRDKYVLGKVPTEV..YTNLNKVITKAVGLQLKVKSK...TVDVEAVMD.ELKTTLADA-k......................................................
K0YSY3_9ACTO/38-256 ............................................apa---KTKTEAKKMLTNVNGRIDTLKK....Q......E.....A..VLPT....G....D....Y.KAQ.....VKDLLKTAF.D..LKDT..L..I...AIAK....GD...ISAFDMQTIEARYQLTLTIADTIKTATTKLTNKVQATHIELGLATTKAVLKLINLTNSSADLEAAQKELKGVLAKVSQYPDLTAKDTATIYVKAKLDKVIWNTR.FDRDKHILGKKSFET..YNTLNSNITKAVGVWFNAHAT...VADVDKAIA.DLQAAYKTA-e......................................................
W4U2Z0_CUTAC/7-227 ..............................................n-KTLSVAEAQKELQVVNARIASLLD....T......Q.....K..SAKK....AfapaN....V.LNI.....IGKLLETAR.R..IKEA..L..V...NVIK....G-...-GIAFLKSIPTRVELLVTMVDTVNGAAHTLQDKAQPAHSHVFLELVHASVLLVTVSATSDQLKDEMAAVKKALAEAQKMPDLKPNDVATFYTKTKLSRVLRQIR.FDRNTCVLPFKRLGT..IYFMSRALLKATGVLMEPLVR...VSEVDQAIT.DVKAAYQDAL.......................................................
A0A2I1MBT0_9FIRM/36-253 ........................................ttslsmd-------EAEVYKQQIRSMRDDVNS....L.....nI.....T..DDQD....Q....E....M.VDE.....FNKSSLEIE.E..NIDK..S..S...Q-GF....GV...ADVYDLSSIPQRLLVLGRVGRTIRFATTQLRYKVDDAHAEIAEYVFEGLVIAASPFHTVDDMKAYMAKFEVLKAKLLSYPEMGLNDTANMYVRADLDVKLHKAR.FMKYNE-LKNKPTYV..IKALDKEVAEITNGRLRPQAT...VLEIYQLSD.RLDQAVAIAL.......................................................
A0A4Q9UZ93_9ACTO/42-259 ...........................................ssad-----QEKAKKALADVDAAINKIKK....A......N.....E..GVPQ....P....N....W.GKE.....FMELFQTAA.E..LRKE..I..E...AIIS....GD...IIAFDPSTIFARAELVTQVGITIDTAVHTLQNKVQAAHVEIGFSVTKAILRIINFTATEDQLKASKQDLIDTLARVSTYPDLTPGDIATVYVKHELRKDIWQTR.INRDANILGKKDFSV..YNELNMAITHAVGVSLDPGAT...VQQVHDEVT.ALNAAYAKA-i......................................................
M4QUU4_STRIN/39-255 ........................................sqantlt------SQKDGIVNTIDQDLNQLQT....I......K.....E..EVKG....T....D....A.EKA.....VTTAIETAD.K..LKSS..L..K...F---....NP...ETIYDINSIGARVEALSDAVQAIVFATTQLSHKVDQAHIDMGFAITKLVIRIADPFTSVDAIKAQVQAIADLEKKVLTYADLKASDRATIYVKSSLDKVIWNTR.FERDQKVLGIKSFAV..YNTLNQAITHAVGVQLNPNVT...VAQVDQEVV.ALQNALTAAL.......................................................
W4UC12_CUTAC/1-145 .............................................mv-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...----------------ATTVDTIHTATTTLQNKVRPAHVELGLEVTKAVLLTANPASTAKELDAEGAALKARLEKVSQYPDLTPNDVATVYVRTNFSKTIWQVR.ADRDRYILGHKSAAV..YKTLNHAITKAVGVRLDPKTT...VGNIQAART.ELLAAYQTAF.......................................................
W4TNS0_CUTAC/40-173 ..............................................t-HELSASDAHNSLQLLNARIATLQS....V......Q.....K..SVPG....S....D....Y.SDQ.....IRDLLKAAF.D..LRGL..I..D...TLAH....GG...IPFYDPSTIMPRIKLAATTIDTIHTATTTLQNKVRPAHVELGLEVTKAVLLTANPASTAKELDAE---------------------------------------.---------------..---------------------...---------.----------appsrlawt..............................................
B0S2D6_FINM2/45-263 ...........................................elke----GLTQAVKSVEDIEPADEKYKE....V......L.....D..KFYE...aH....D....FlDKE.....IKVAEMKQR.Q..AVGS..A..Q...AVGA....LE...NSIYDLTTIPVRVQLMIRIGRAIRFATTELSNKVIAAHTKITEYIITGILYAVNPFASEQQIMEYIQRFDQLEQELLSYPDLGPNDIATIYKKAAVWREIREAK.KVRSSRTRFGNSFIV..-RDLSEEISKTVGLQFRITVK...CGELDDQVK.KLHAAME---ki.....................................................
D7BMD1_ARCHD/50-269 ..............................................a-APIGKTEAKEKAADVDTVIAEIKE....I.....gA.....T..SRPD....I....K....W.GKE.....FEGLFKTLY.E..LKDE..L..I...AIST....GN...VPAFDTTTILSRAKLAAKIGQAINTGATTLRDKVQAAHVKIGFAVTRSIIRLTNLSSTEAQLNESTEELGNILTEVADYPDLTPEDNATIYVRNELTQKIWKTR.WNRDTNILRKKSFAT..YNKLNRNITKAVGIELGPRST...VKQVREAVT.ALDNAYKEAL.......................................................
Q8CX01_STRA5/39-254 ...............................................NHVNSNNQAQQMAQKLDQDSIQLRN....I......K.....D..NVQG....T....D....Y.EKT.....VNEAITSVE.K..LKTS..L..R...A---....NP...ETVYDLNSIGSRVEALTDVIEAITFSTQHLANKVSQANIDMGFGITKLVIRILDPFASVDSIKAQVNDVKALEQKVLTYPDLKPTDRATIYTKSKLDKEIWNTR.FTRDKKVLNVKEFKV..YNTLNKAITHAVGVQLNPNVT...VQQVDQEIV.TLQAALQTAL.......................................................
G4CZ87_9ACTN/34-255 ........................................savssnt------SDAHALLGDVNNRIHSLTNdlkvA......K.....A..SLSP....K....E....V.IDT.....ISDLLKQAK.I..LKAQ..L..E...KVIK....GV...TTFV--KSIPARVELFLTMCDTTHTATLTIQDKVQNAHTVVFDEIAHAINVLISLDSTPAQLTDEVAALKKALATAQAMPDLKPTDVATKFVRAKLGRLMAQVL.FDRDTCVINYKDGDT..IRLLNRAIDRAGLIRGNAWVR...VAEVDQAMK.DLKVAYQDAL.......................................................
W4UF19_CUTAC/1-155 ..............................................m-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...----DLSTIPARVDLLTTSVKTIQQANHNLVNKVEAAHVELGFSITRALIRTINPTSTAAQLAESKADVLSTYAKVAAYRDLKPTDAATVYVKNRLNTKIWQTR.INRDKYLL-GKNAEG..YKAINKALTHATGVWFNPATT...VKQVDDEVK.ALDLAFQAT-l......................................................
W4UF60_CUTAC/41-157 .............................................kt--ALTTDQIKAERSALNSRINMLQE....T......Q.....K..AIPG....S....Q....Y.ADQ.....IEDLIKTAL.D..LSGA..I..D...TIAH....GG...VPAYDPATIVPRIHLAIDAADAIKTGNTTLQHKVKKAHVGLGLEIAK---------------------------------------------------------.---------------..---------------------...---------.----------rrssllirra.............................................
K0YSC1_9ACTO/128-346 ...........................................aaap----AKAQAQQMLSEVNDRINTMQK....R......Q.....A..VLPT....G....D....Y.KPQ.....IRDLLTTAF.D..LRDT..L..T...AIIT....GD...VSKFDMNTIGARLELTLTIADTIETATTKLTTKVKPTHVELGLATTKAVLKLINLTNSTSALQAASQELKDVLARVSQYPDLSPSDTATIYVKAKLDKVIWNTR.FARDRNILGKKSFRT..YHTLNRNITKAVGVWFNARAT...VADVDKAIA.DLQAAYRVA-e......................................................
G5KDX6_9STRE/35-251 ........................................hvvvsqv------NNQQQIKQKLDQDSVQLNT....I......K.....N..QVQG....T....D....Y.EKP.....VDTAINAVD.K..MKSS..L..G...G---....NP...ATIYDLGSIGPRIEAITDVIEAINFSTHNLTNKVSQANVDMGFGITKLVIRIADPFASVDSIKAQVAEVKQLEQKVMTYPDLKPTDKATIYTKSKLDKAIWDIR.VQRDQKVLNKKSFDV..YNALNKAITHAVGVQLNPNVT...VQEVDQEIV.NLQMALQTAL.......................................................
A0A1V4KWX6_PATFA/24-104 ........................................tphcsts-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...-----------------------------------------------------------------------------------KDDTATIAYKQTLRKTIHEVR.VGRNKNIVGKKDQAV..VDTLNKEISKADKVRANAKST...VAQLRH---.----------yeygvdvamvr............................................
A0A1G7PCM6_9LACT/500-714 ......................................ivkdhkvas-----------DLEELEIEKDKLVK....I......S.....E..RVLS....K....K....Y.EKS.....LEQAFKLID.K..LGDE..L..D...GIK-....QT...DTVFALNTIGTRMNALKNIIESIDYATSELKNKDIAIHKEYGFTITRTLVALSDPFASKEKIEKRIAELLALEEKAANTPDLNLDSRANIYVQSILDEVIWNTR.FRRDKEVLGKQPYEV..YSKINATLTKAVGVQLNPNST...LRDVYSMIN.ELESL-----fddk...................................................
W4U0R1_CUTAC/41-169 .............................................kt--ALTTDQIKAERSALNSRINMLQE....T......Q.....K..AIPG....S....Q....Y.ADQ.....IEDLIKTAL.D..LSGA..I..D...TIAH....GG...VPAYDPATIVPRIHLAIDAADAIKTGNTTLQHKVKKAHVELGLEIAK---------------------------------------------------------.---------------..---------------------...---------.----------rrssllirrapspgsrrdqssq.................................
W4UFP1_CUTAC/43-263 ..............................................n-KTLSVAEAQKELQVVNARIASLLD....T......Q.....K..SAKEafapA....N....V.TNI.....IGKLLETAK.R..IKEA..L..V...NIIK....GG...--VAFLKSIPTRVELLVTMVDTVNGAAHTLQDKAQPAHSHVFLELVHASVLLVAVSATSDQLKDEMAAVKKALAEAQKMPDIKPNDGATFYTKAKLARVLRQIR.FDRNTCVLPFKRLGT..IYFLSRALLKATGVLMEPLVR...VSEVDQAIT.DVKAAYQDAL.......................................................
W4TLA0_CUTAC/80-300 .........................................avssnt------ADAHKLLEDVNGRITSLNDdlkvA......K.....A..SLSP....M....E....V.IDT.....IADLLKQAK.Q..LKAQ..L..E...KIVK....GV...VTFA--TSIPARVELFLAMCDTTHTATLTLQDKVQNAHSTVFLAIAHAINVLITINSTPAQLTDEVAALKKAIAAAQAMPDLKPTDVATKYVRAKLGRVMVQVR.FDRNTCVINYKDRDT..VRLLNRAIIRAGQVRSNAWVR...VADVDQAIK.ELKAAYQDAL.......................................................
B0S2D5_FINM2/35-257 .....................................qgaeeteklg------------IDEAEVYKRQIKS....I......Q.....N..EVNA....I....Q....V.KREdekqmVDKFNETSL.E..ISDK..IdqT...AVGM....GV...ADIYDLSSIPQRLLLLGRMGRAIRFATTQLRYKVDAAHAEIAEYIFGGFVIAASPFHTVEDMKVYMAQFESLSQKLLSYPDAGLNDTANIYVRSDLDHKLAKAR.SLKYHE-LKNMSGAV..IDKLNAEIHEITLMRLRPQET...VAEIYQLGD.RLDQAVFEAL.......................................................
W4U884_CUTAC/1-90 .............................................ml-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...----------------------------------------------------------------------STYAKVAAYRDLKPTDAATVYVKNRLNTKIWQTR.INRDKYLL-GKNAEG..YKAINKALTHATGVWFNPATT...VKQVDDEVK.ALDLAFQAAL.......................................................
A0A1W1Y2P2_9LACT/692-773 .......................................aqaedvqa-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...-------------------------------------------------------------------------------------NKASFSFKRELADLIWQTR.RERDQFVLGKVPSDV..YTNLNKVITAAVGVQLAVNAT...NGEVTQAMD.SLKNALAKA-k......................................................
A0A2I1MBV7_9FIRM/55-283 ..............................sadqqkleiaevrgelt-------KAQKSVEGVEAADEKYEE....Cl....kQ.....F..DEAV....R....T....V.SLE.....IDDYEQSVQ.NgsLSQQ..K..-...GVAG....--...GSIYDLTTIPVRVQLLIRIGRAIRFGSTELSNKVVAAHTKLTEYILTGILYAANPFANEGQIMDYIDRFEALEQELLAYPDLSPEDIATIYKKAAYHRTIREAR.KVRNEANRTGRKFQA..-KVLDKEISKAASLWWRITVT...CGELDAEEE.KLIAAIE---kva....................................................
W4TXR1_CUTAC/7-227 ..............................................n-KTLSVAEAQKELQVVNARIASLLD....T......Q.....K..SAKE....AfapaN....V.LNI.....IGKLLETAR.R..IKEA..L..V...NVIK....G-...-GIAFLKSIPTRVELLVTMVDTVNGAAHTLQDKAQPAHSHVFLELVHASVLLVTVSATSDQLKDEMAAVKKALAEAQKMPDLKPNDVATFYTKTKLSRVLRQIR.FDRNTCVLPFKRLGT..IYFMSRALLKATGVLMEPLVR...VSEVDQAIT.DVKAAYQDAL.......................................................
A0A0X8FC58_9LACT/649-754 ............................................dlh-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...--------------------------------------------------------AKTVDVQAVMEEIKGQLNEAREIAQATLNARASKERKLELRDLIREVR.SIRDSELLGKVSFNA..YNNLNKVITKAVGTRLSLKAS...NAEVDEAAN.ALRQALAAA-r......................................................
A0A0X8FC58_9LACT/404-588 ............................vldklgqmamdigrsvadg-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..M...VVSY....HP...GSFYNPNTFRLRARVLRKGAELIKTATTEWRMKPQIVHSKAGLEITHAFMSVVDPFSTAERLTKRLNELEALEVFGNAYRNITPKDIATTYIKEKLDKAIWDTR.FKRDEYILSKVPFEV..YHKLNKAITRAVGVQLYSETR...VYQIDDAVA.ELEAAYGEA-v......................................................
W4TIT7_CUTAC/43-263 ..............................................n-KTLSVAEAQKELQVVNARIASLLD....T......Q.....K..SAKE....AfapaN....V.INI.....IGKLLETAK.R..IKEA..L..V...NIIK....GG...--VAFLKSIPTRVELLVTMVDTVNGAAHTLQDKAQPAHSHVFLELVHASVLLVTVSATNDQLKDEMAAVKKALAEAQKMPDIKPNDVATFYTKAKLARVLRQIR.FDRNTCVLPFKRLGT..IYFLSRALLKATGVLMEPLVR...VSEVDQAIT.DVKAAYQDAL.......................................................
A0A2I1MBP9_9FIRM/107-277 ..........................................gvnpe-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....NP...QQFFYIGSVGVRIQLLRKVSQFINQMTTEYIYKIQEAHNKAAQISFEAIMIAINPFNGRKDVLNAIEKFDENAEKIKDYRDLTSGDQATIYVKRLMYKNIGQAR.RSQNK----------..---------------------...---------.----------yfgkgtygmrgkeeyiqniyknevndinkqvgqkitfgqlveldarlksatssal
E0QPF2_9ACTO/43-261 ............................................pet---LTRTTAAEYLDQINNAIANVQE....A......Q.....K..NDPQ....A....D....W.GKE.....ISKLLSTAA.E..LSQV..M..E...SVAQ....HG...MNLADADLEIARAQLVVEIGSTIKKSSDNLRYKIQKAHVELGFAVTRAIIRVANIGAKTPQLLDSIKDLQETYERVSTYPELTATSRANFYIKNGLNKFIWKVR.VARDKNILGKKPYKV..YRQLNREITKAVGVWFRARAT...VQDVANAVE.RLDNAYKTAL.......................................................
W4U4F8_CUTAC/1-119 ..............................................m-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...---------------VATTIDTIHTATTTLQNKVRPAHVELGLEVTKAVLLTANPASTAKELDAEGAALKARLEKVSQYPDLTPNDVATVYVRTNFSKTIWQVR.ANRDRYILGHKSAAV..YKTLNHAITK-----------...---------.----------psaf...................................................
W4U2E0_CUTAC/19-219 ....................pavssntadahkllegvngritslndd----------------------LKV....A......K.....A..SLSP....M....E....V.IDT.....IADLLKQAK.Q..LKAQ..L..E...KIVK....GV...VTFA--KSIPARVELFLAMCDTTHTATLTLQDKVQNAHSTVFLAIAHAINVLITINSTPAQLTDEVAALKKAIAAAQAMPDLKPTDVATKYVRAKLGRLMVQVR.FDRNTCVINYKDRDA..VRLLNRAIIR-----------...---------.----------lgrsvamrg..............................................
G5KGP4_9STRE/33-250 ........................................stpvtni------TETTNAASVIENKENELRS....V......K.....E..SVKG....T....E....L.EAT.....VNDAITKVD.N..MKTS..L..R...A--A....NP...TTIYDLGTIGARVEALTDVINAIVFSTTQLTNKIDKAHIDMGFAITKLVIRLVDPFASIDSIKEQSKTIESLKQATLTYPDLKSTDRATIYKKAVLDKAIWNTR.FERDKKILGVKSFTV..YNTLNQSITHAVGVQLNPNVS...VANVDRAVN.DLQNALAIAL.......................................................
W4TYX4_CUTAC/12-235 ...........................................arqh----AQVDAEQALAQVNARIAELHK....MpqaqvpA.....S..EAPK....V....N....Y.GEE.....IRKLLDTAF.E..LRTA..I..E...SIIA....GK...VPPVDLSTIPARVDLLTTSVKTIQQANHNLVNKVEAAHVELGFSITRALIRTINPTSTAAQLAESKADVLSTYAKVAAYRDLKPTDAATVYVKNGLNTKIWQTR.INRDKYLL-GKNAEG..YKAINKALTHATGVWFNPATT...VKQVDDEVK.ALDLAFQAT-l......................................................
A0A2I1M9L2_9FIRM/43-244 npnavnpekikdiidraedlikvvnklpipgkgpyvkalekiigalk-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...--NVDPSKAGPRVQLASESIEAIRFSINDIQGKTKKAHVEIGLQITKAALTLADPYASNEKLEKANEQLKEAMNTAKESADITDEDVATIYVKKDLNKLIDYAR.KLK----LNNKELTKeeKAQLSDAIKKAVHTKNKARVT...VAEINQATE.ELQSFL----enll...................................................
A0A371IP17_9FIRM/39-260 ..................................rafaeapvqtkyn----------QVESEVEAVEAEVAG....S......E.....Y..EQYA....A....Q....L.ATE.....LDKMQAQVE.E..VATP..F..N...GERF....NT...ETIYDLDSIGARLELFTEISKTIATASNDLNKKVRQAHIEIGAEITKAIIIAANPFAGTDEVKGEIDKLQAVIEKARGMADVTSTDKATIYVKKALDSAIWNTR.FERDSKVLGKVPFKV..YNELNKKITNAVGVQLSLRST...VADVEQAIK.DLDEALKEA-i......................................................
W4UFZ3_CUTAC/20-240 .........................................avssnt------ADAHKLLEDVNGRITSLNDdlkvA......K.....A..SLSP....M....E....V.IDT.....IADLLKQAK.Q..LKAQ..L..E...KIVK....GV...VTFA--KSIPARVELFLAMCDTTHTATLTLQDKVQNAHSTVFLAIAHAINVLITINSTPAQLTDEVAALKKAIAAAQAMPDLKPTDVATKYVRAKLGGLIVQVR.FDRNTCVINYKDRDT..VRLLNRAIIRAGQVRSNAWVR...VADVDQAIK.ELKAAYQDAL.......................................................
U1FCU7_9ACTN/37-256 ........................................pvsssda------DHAKSIIKDLDGQADKLGD....L......L.....K..FLPA....G....E....Y.KDQ.....VVDLLHTVF.N..LRRA..A..Q...KIAT....GK...VPFYKLDTLSARVQLVTTIGQTIHDSVNNFQTKPRQANVTMGLEITKAVVILVDPMTTKDEITAEIAAVKDRYKAGLAMPDLKDTDPATIYTKSHLNKAIWQVR.HNRAKNLAGKKDRAV..IKELNKEISKAVGVWFRAKST...VGDCKAAEA.ELNDAYQKAL.......................................................
W4U6H3_CUTAC/36-149 ...........................................arqh----AQVDAEQALAQVNARIAELHK....MpqaqvpA.....S..EAPK....V....N....Y.GEE.....IRKLLDTAF.E..LRTA..I..E...SIIA....GK...VPPVDLSTIPARVDLLTTSVKTIQQANHNLVNKVEAAHVELGFSITRA--------------------------------------------------------.---------------..---------------------...---------.----------.......................................................
A0A1W1Y2P2_9LACT/422-607 ...................yvidklgsmaqdigqsvikgmvsffepg-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...-NFYNVNTWRLRAQLFVEAAKAIHTATHDWTRKPQIVHSKAGLEITHAFMAVVDPFSNVERLTKRIKDMQGLVAYGNNFRDITPLDIATTYVKRALADTIWQTR.FDRDEYILSKVPFEV..YHELNKAITKAVGVQLNPETL...VFEIDNAIA.NLKGAYQKA-i......................................................
A0A1H8EX60_9FIRM/1-144 .............................................mi-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...-----------------HCGKTISIATTELTNKIQKAHIEIGLEITKAVAKAINPFESVEGLKEEESVLDSLIEKVSTYPDLTADDTATIYYKSKLDKTIWNTR.INRDKYILNKKSFET..YKELNKAITKAVGIQLNPASK...CIDIDNAIT.NLNLAYETAL.......................................................
W4TNF4_CUTAC/3-199 ..........................................qaqvp-------------------------....-......A.....S..EAPK....V....N....Y.SEE.....IRKLLDTAF.E..LRTA..I..E...SIIA....GK...VPPVDLSTIPARVDLLTTSVKTIQQANHNLVNKVEAAHVELGFSITRALIRTINPTSTAAQLAESKADMLSTYAKVAAYRDLKPTDAATVYVKNRLNTKIWQTR.INRDKYLL-GKNAEG..YKAINKALTHATGVWFNPATT...VKQVDDEVK.ALDLAFQAAL.......................................................
A0A0X8FC58_9LACT/595-676 .....................................padqqiapna-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...----....--...-------------------------------------------------------------------------------------------LKRELKDLIWNTR.FERDGSILGNVPTEV..YTALNATLTKAVGLQLDLHAKtvdVQAVMEEIKgQLNEA-----reiaq..................................................
A0A2I1MBP3_9FIRM/71-208 .........................yqedlvtlaedrafelppqaqr-------------------------....-......-.....-..----....-....-....-.---.....---------.-..----..-..-...---Y....NP...DTIYDLDSIAPRIKLLGLTGIFIHRCSTELIYKVQAAHSKAAGEVAIALVTAFNPFASVDDIEAACERISNVMDELVQMPDLTADDFATIYLKKVFNKDVRE--.---------------..---------------------...---------.----------akkllnkyyrd............................................
#=GC seq_cons ............................................t.s............ht.lpt..tpltp....h......t.....t..th.t....h....p....h..p......htphhpth..p..lptt..h......t.......s.....shhshsoIssRlpLhhphscsIphusppLpsKlptAHscluhtls+ullhhhsshuostplptphttlpthhtcs.shPDLpssDhAThYsKscLs+hIapsR.hpRspplLst+shps..hptLN+sIo+AsGV.hpspso...Vtplcptlt.pLptAhttA........................................................
//
