#=GF ID CATRA-N
#=GF AC PF20269.2
#=GF DE CASPASE and TPR Repeat-Associated N-terminal domain
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Aravind L
#=GF GA 27.00 27.00;
#=GF TC 55.50 29.30;
#=GF NC 26.60 24.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 32868406
#=GF RT Identification of Uncharacterized Components of Prokaryotic
#=GF RT Immune Systems and Their Diverse Eukaryotic Reformulations.
#=GF RA Burroughs AM, Aravind L;
#=GF RL J Bacteriol. 2020; [Epub ahead of print]
#=GF DR INTERPRO; IPR046922;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC One of two constant domains forming the CATRA module which is in
#=GF CC turn C-terminally fused to a diverse range of conflict effector
#=GF CC domains. This gene, along with a gene encoding the CATASP domain
#=GF CC and a gene encoding a TPR repeat region fused to a CASPASE
#=GF CC domain, forms the three gene island making up the CATRA conflict
#=GF CC systems. This alpha/beta domain is predicted to be involved in
#=GF CC recognition of invasive molecules or in the transmitting of a
#=GF CC signal through conformational change, enabling CASPASE-mediated
#=GF CC proteolysis to free the fused effector domains.
#=GF SQ 78
#=GS A0A3N2PBA6_9ACTN/6-202 AC A0A3N2PBA6.1
#=GS F8AYB9_9ACTN/11-242 AC F8AYB9.1
#=GS A0A1V9KGZ6_9ACTN/1-209 AC A0A1V9KGZ6.1
#=GS A0A7W9DQK5_9ACTN/8-219 AC A0A7W9DQK5.1
#=GS A0A8J3MII1_9ACTN/9-216 AC A0A8J3MII1.1
#=GS A0A7W7WRP1_9ACTN/6-203 AC A0A7W7WRP1.1
#=GS A0A010YLS5_9ACTN/8-141 AC A0A010YLS5.1
#=GS A0A4R4P2T3_9ACTN/7-207 AC A0A4R4P2T3.1
#=GS A0A1Q5KHE4_9ACTN/1-194 AC A0A1Q5KHE4.1
#=GS A0A162J0A8_9ACTN/1-206 AC A0A162J0A8.1
#=GS A0A1I2JCC6_9ACTN/8-255 AC A0A1I2JCC6.1
#=GS A0A6G2B5T9_9ACTN/6-228 AC A0A6G2B5T9.1
#=GS A0A1G7XEC5_PSEOR/9-212 AC A0A1G7XEC5.1
#=GS A0A4R6RRX8_LABRH/13-209 AC A0A4R6RRX8.1
#=GS A0A6F8XR89_9ACTN/77-280 AC A0A6F8XR89.1
#=GS H2JYC8_STRHJ/11-228 AC H2JYC8.1
#=GS A0A1Y5YAA2_KIBAR/21-210 AC A0A1Y5YAA2.1
#=GS A0A810NDN0_9ACTN/19-239 AC A0A810NDN0.1
#=GS A0A2I2KP68_9ACTN/26-242 AC A0A2I2KP68.1
#=GS A0A1S1QFF2_9ACTN/10-251 AC A0A1S1QFF2.1
#=GS A0A1S1R1R4_9ACTN/1-206 AC A0A1S1R1R4.1
#=GS A0A2T0STI2_9PSEU/10-201 AC A0A2T0STI2.1
#=GS A0A1H1Y8E9_9ACTN/8-203 AC A0A1H1Y8E9.1
#=GS A0A5M3WCM8_9ACTN/8-218 AC A0A5M3WCM8.1
#=GS A0A8J4DTL3_9ACTN/7-214 AC A0A8J4DTL3.1
#=GS A0A1H9JCD7_9ACTN/6-228 AC A0A1H9JCD7.1
#=GS A0A0D0VYV8_9ACTN/10-229 AC A0A0D0VYV8.1
#=GS A0A7W5YUH3_9ACTN/5-191 AC A0A7W5YUH3.1
#=GS A0A5M3XYX8_9ACTN/2-121 AC A0A5M3XYX8.1
#=GS A0A1G7XDB7_PSEOR/8-206 AC A0A1G7XDB7.1
#=GS K0K976_SACES/8-193 AC K0K976.1
#=GS A0A6M1L7X5_9ACTN/6-191 AC A0A6M1L7X5.1
#=GS A0A7M2T6A0_STRCW/11-230 AC A0A7M2T6A0.1
#=GS A0A1X7C7J5_9ACTN/12-224 AC A0A1X7C7J5.1
#=GS A0A4R2JHB5_9PSEU/9-214 AC A0A4R2JHB5.1
#=GS A0A5M3VZH2_9ACTN/7-241 AC A0A5M3VZH2.1
#=GS A0A1I0BYY8_9ACTN/7-249 AC A0A1I0BYY8.1
#=GS A0A4R4XPL7_9ACTN/10-182 AC A0A4R4XPL7.1
#=GS A0A4R1DVC6_9ACTN/10-215 AC A0A4R1DVC6.1
#=GS A0A7K1KTA6_9ACTN/10-197 AC A0A7K1KTA6.1
#=GS A0A7K2ZQE5_9ACTN/5-142 AC A0A7K2ZQE5.1
#=GS A0A8J3HP52_9ACTN/10-217 AC A0A8J3HP52.1
#=GS A0A4R1HJ22_PSEEN/11-218 AC A0A4R1HJ22.1
#=GS A0A8J4DVC9_9ACTN/9-209 AC A0A8J4DVC9.1
#=GS A0A7W7MCH4_9ACTN/10-214 AC A0A7W7MCH4.1
#=GS A0A841BUK7_9ACTN/7-222 AC A0A841BUK7.1
#=GS A0A7K2YF25_9ACTN/1-199 AC A0A7K2YF25.1
#=GS A0A2T0RCI2_9ACTN/119-304 AC A0A2T0RCI2.1
#=GS A0A4U3MJM4_9ACTN/7-171 AC A0A4U3MJM4.1
#=GS A0A543C0Q5_9ACTN/8-204 AC A0A543C0Q5.1
#=GS A0A545APA1_9ACTN/10-220 AC A0A545APA1.1
#=GS A0A010YLS5_9ACTN/132-171 AC A0A010YLS5.1
#=GS A0A4R6J9T8_9ACTN/10-207 AC A0A4R6J9T8.1
#=GS A0A438M8U0_9ACTN/10-182 AC A0A438M8U0.1
#=GS A0A7X0IC25_9ACTN/10-222 AC A0A7X0IC25.1
#=GS A0A810NBD0_9ACTN/1-176 AC A0A810NBD0.1
#=GS A0A2S6GT20_9PSEU/8-200 AC A0A2S6GT20.1
#=GS A0A6F8YXY0_9ACTN/109-313 AC A0A6F8YXY0.1
#=GS A0A429FKE3_9ACTN/27-229 AC A0A429FKE3.1
#=GS A0A1S1QF37_9ACTN/108-315 AC A0A1S1QF37.1
#=GS A0A239ISV6_9ACTN/8-222 AC A0A239ISV6.1
#=GS A0A1S1QG02_9ACTN/4-216 AC A0A1S1QG02.1
#=GS A0A1C4RG02_9ACTN/10-215 AC A0A1C4RG02.1
#=GS A0A516RIQ3_STRST/8-205 AC A0A516RIQ3.1
#=GS A0A841C463_9ACTN/10-190 AC A0A841C463.1
#=GS A0A841D6H7_PLAVE/8-194 AC A0A841D6H7.1
#=GS A0A4U3MG16_9ACTN/7-204 AC A0A4U3MG16.1
#=GS A0A428YTD4_9ACTN/5-209 AC A0A428YTD4.1
#=GS A0A2B8AVU4_9ACTN/6-216 AC A0A2B8AVU4.1
#=GS W7ST62_9PSEU/10-203 AC W7ST62.1
#=GS A0A840NXD4_9ACTN/19-213 AC A0A840NXD4.1
#=GS C7PYD7_CATAD/15-225 AC C7PYD7.1
#=GS A0A8J4DSW8_9ACTN/10-205 AC A0A8J4DSW8.1
#=GS C7PYD3_CATAD/9-236 AC C7PYD3.1
#=GS K0K3J1_SACES/6-200 AC K0K3J1.1
#=GS A0A0M8UWR4_9ACTN/25-215 AC A0A0M8UWR4.1
#=GS A0A841BFR8_9ACTN/20-188 AC A0A841BFR8.1
#=GS D3D729_9ACTN/8-216 AC D3D729.1
A0A3N2PBA6_9ACTN/6-202 ..................................................w-LLAHEF.........APLDG...PVLP---PRLRAAWHGVTTTLGM.RSAVDVD-...---ALPLGDG.............................VGTGS.L..T.VLGHAHRAv.eGDALYQAVLSSSGDAACLTV..LLAPNDNAR...............GWASIEAELDRT........EPAS.PP............................TDL.GGARVYLGLV.............................DGAVDRATAE..........aLAPVLAAEVPDAG.......................DG.-..TW................IRR.PSLTTHG....FLL.WEAPP-......-TR..PHQRRLVLVGAA..SAEVELDAFSWTPG................
F8AYB9_9ACTN/11-242 ...................................................ELVVHLF.........APAEG...TTGIGAYRELGRIWSACTGELAM.HKEVTAT-...LPTAPPIDP-.............................DLLAE.G..-.PIAACEAA...GDGVIQAIFRCERDTFCLSL..VLDPANLV-...............SWADLDRRWSRIvag.sadsLSDR.ED............................FLF.GEARLYLAQShqipadvhh..........aspgrvppgdT--------AggtglggmsreLAAAVRAAMPGDV.......................AE.-..PW................WRD.GVLVPTG....FAV.WEAVERrn..pdADA..RAVRRIAAVTAH..GDGDTLSGWTWTPG................
A0A1V9KGZ6_9ACTN/1-209 ..................................................m-----AF.........APAET...DIGGRARDHLARMWRACG-SLGM.REPVPGTS...VPADRIDFGSa...........................pPVAPR.F..T.LLAAAQRT..gDDSVYSAFAFADHDVVGVVA..LLAPNDTAGg............ltQWADLDAEWNAAva...aagRPPG.PP............................DLL.GEFRVFEALH.............................GPWLGRRDRA...........MCELVRRHAPRTG.......................SE.-..PW................WAG.FDRTEHG....FSV.WRSTEA......AEP..GDATDLYVLAPA..RYEADLDEWAWAA-d...............
A0A7W9DQK5_9ACTN/8-219 ...................................................QLVAHLY.........APTDG...PDAGAAYRALREIWRYCRLSLHM.SEPIPGIG...LPHLLPESPD.............................SFPTG.G..EvALAAQERP...-GADCQAVLRRHHDLFNLSI..ALAPPEATApdd........gdwpWWRMLDLQWDAV........LAQH.TP............................HLV.GEARLYLARV.............................GDETGVRAAGp.........aLYDHLNDLLPKAA.......................RG.-..RP................GRR.GVPASDG....LAL.WETVPA......PDE..RPARRFLLAIAP..GADPAASAWVWSRG................
A0A8J3MII1_9ACTN/9-216 .................................................av--LAHGF.........LTAKAa.aDPASPAGQALARTWQRIR-DSGM.TAPVHGW-...-PTELSTDSP.............................GYAER.E..V.VLAAVCQV..lPDGLREAYVYRAHDVIGISV..VQSEGDART...............DWSGLDTPWFDG........WPHG.GS............................GVL.GTATVYLGLL.............................PGLGPASMPS..........aDAAALAAQFAAAV......................pGG.D..GW................ASH.WWRPTRE....LML.WELPPG......DDApvPTDRRLAAVAAV..DDEPATDEFFW---gat.............
A0A7W7WRP1_9ACTN/6-203 ...................................................ALLTHEF.........TRLDQ...PTVT---PALLDTWQHLVATLEM.RSDTDSAT...LALGVDVPTG.............................GLAVL.G..-.-YAKRSTE...DIPVHQAALSSTGDAACLTV..LLAPQDPDR...............TWAAMDSELALL.......dRVAP.GT............................DHL.GSARVYMGLV.............................DAPLDPETIV..........aIEKTLGGEFPEVG.......................EG.-..AW................TRH.RSRTTEG....FLI.WEVPT-......-SP..ARQRRFVLVAEQ..SAELALDAFAWTPG................
A0A010YLS5_9ACTN/8-141 ...................................................ELVVHVF.........APVDG...PRAAEGYAAVRELWRRCRTELGM.TSALSGSG...PSTDLPATLD.............................ELP--.-..-.DLTAQKAP...-DRLYQAILRRFPTSLSLSV..LLSPGDAG-...............GWSDLEREWAGV........AGSP.SD............................ALI.GVAYLYLGKV.............................SGL-------...........-------------.......................--.-..--................---.-------....---.------......---..------------..--------------dgvatteld.......
A0A4R4P2T3_9ACTN/7-207 ...................................................ALVAHVF.........VAAEG...STGDEDRRYLRGVWRACDEVLGM.TDGVAGLD...--ADPPAGWD.............................GTAAA.S..G.VLAARTRP...GSGVQQAILRRERDVFCLSV..ILEPDPSEG..............iGWAELDARWSRA........LAAP.TR............................GTV.GTARIFVARL.............................GADATDRA--...........RAGELVAGVPVEE......................gAA.A..LW................PER.GIAVPEG....FMV.WEASAP......DDR..RVERRLVVIARR..DGEHDLSDWTWI--g...............
A0A1Q5KHE4_9ACTN/1-194 ...................................................-----MF.........VPLDG...TRAGEGVASVRSMWQRFRELQQA.ERELYAT-...LPVEVPHDLP.............................DPSEH.G..S.VVVAGVQS...ADRLDQAILRRHREILNLSV..LLGAGPDR-...............DWTGLRERVETV........VGPL.GA............................CHL.GAVTMELGKL.............................PEDV------...........-PGDVDLTEPEGD.......................DE.S..RWrvl..........rmlGRT.GADARLG....ALA.WSANRR.....pAMP..HFVRYLM-----..--------------hmtairhqqrtyrrlt
A0A162J0A8_9ACTN/1-206 ..................................................m----HVF.........VPTGG...EQAGRLYDHLQDVWARCADRLGM.HFPIDVLG...VPATPPRRHQ............................pETTRI.Q..E.PIAAQRRI...GDGVFQCLLRREHDVLCLSV..MLAPPPEAG..............vSWRELQALWAQL........SEPV.PD............................GLL.GWAELYLSRL.............................ADPGPERVESt........aeLGGVCRELMPAPI.......................PH.R..DF................DAS.GTTTPSG....YAM.WEADPD......DIA..RVARRIVLVAPH..QRDPEFSAWVWTRG................
A0A1I2JCC6_9ACTN/8-255 ..................................................a-LLVACFvptapvddaLPDSG..aPHGDSAHAYLDDLWRACR-ALGM.TAPIPGLP...LPAEHLPAIP.............................SRTRE.L..E.ILAAADRG..gGTAVYSVYVFAEHDTAGLVA..LLAPNDTDAg............ldRWGELLAEWRAAlagigrpgGGPP.TE............................SVL.GEFHVYEALR.............................RRTFTGTEQA...........LCEAVRRYAPGAGpsaagsgptasgtagsdptgsgaAG.A..NW................WRG.YDRTDHG....FSV.WRREED......HTR..DLVSDLYVVAPA..RLEAELDAWAWA--vd..............
A0A6G2B5T9_9ACTN/6-228 ...................................................ALGVHLF.........VLTGG...AHRDSALALLAEVWNKCGTVLGM.TEPVERTG...VAMQPQGGWEpf........................lgaTATRT.A..G.LLAARKRP...GTGVRQAALRREHDVLCLSV..MLAPPPEEG..............lGWRDLDAQWSTVlpagnvleGQPR.GR............................GVL.GVARLYLARL.............................AEPGVRPTPEpd.......rpLVAAVRARTPADP......................aAP.D..GW................PYG.GVTVSQG....FAV.WEASAA......RDA..RPERRLVVVAAH..DHDRELTAWTWTT-r...............
A0A1G7XEC5_PSEOR/9-212 ...................................................ALVVHLF.........VAADR...PENEADLAYLHAVWQRCVDRWAL.TERVADLP...ADLGLRTGTG.............................LLAGR.K..R.PTADGSRT...-PHVQAALLRHEHDTYCLSV..MREPVGA--...............TWTRLEREWESIl......nGLTA.PT............................GLI.GCAQVFLARL.............................TGSGPPDPAQ...........LSEAIRDRLPASL......................lAA.G..EW................WRA.GVTADPG....FAV.WEASER......SDE..RALRRLVVVADA..DADDLLSSWTWVV-g...............
A0A4R6RRX8_LABRH/13-209 ...................................................ELVAHFY.........TVHDD...QDT-----AIRAIWSRCGTELLA.DRAVPSTG...LPVEMPGTV-.............................--PTS.S..A.LIAARRTA...-DGSVQAIARREHEIFNVSV..LLKHRSGQ-...............SWADLDRTLDAL........LGDS.PA............................PLL.GGARLYLGLV.............................TNGLPDGPEEt........vgLGRAIAQRLPEPQ.......................LT.T..GW................WHQ.GLTTDVQ....LLV.WETGDT......SDD..RETRRFAIITDP..AHEPELSAWTWSR-r...............
A0A6F8XR89_9ACTN/77-280 ...................................................ELVVHAF.........APLEG...PGRDPAYQQIRRLWTATR-RLGA.TEAIGGG-...-SPDLPDECT.............................RLAAG.P..-.VVAAQQSA...-DERLQVVLRREHDVLNLSI..GWLADPKAPp.............rTWAEWEERWAAV........AAGG.TD............................ELI.GIVRLYIGTQ.............................PATRRGGPPArp......pveVAAELAAGLTEQD.......................GT.-..LW................-ND.GVLV-EG....CVL.WELPPF.....gGQA..RRERRILALATP..DREAQMSALAWWRG................
H2JYC8_STRHJ/11-228 ...................................................ALLLHYF.........FAVE-...RLALRGTHHLGLLWDACAQAGMD.RTPSPGGD...L--SLPTDL-.............................DAGLG.G..R.TLCQRTDA...-TATRQATLYSLNGVVGLTV..MLAAEEGPGrtgvqsaarlsalaqDWDEAYARATAA........AGHV.TDd.........................grTVI.GSVRVHRSLT.............................LPGGPTPGDPa.........aVGEELRRELAPQT.......................--.-..-Q................LSR.PVNLTGQ....LVL.WELTRR.....gDPF..STDRELLATGPAtdEQEGLLDDWTWTT-v...............
A0A1Y5YAA2_KIBAR/21-210 ...................................................ELILHVF.........AHADD...RKP-ADVAEIGALWTRFADELGL.TEPVPLLG...LPMNPDRLT-.............................GFGVG.T..A.VLAARQRP...-DTHVQAVLRGMHDALNLSV..LAALPGA--...............SWQQLDAMVKGV........LGEM.SQ............................AFI.GVAWLYQGKD.............................EH--------...........IDAGVRSFEELGS.......................E-.G..GR................VRR.GCELEPG....IVL.WEFSGR......EDT..RAERRFVVLAPP..DRDDEQSDWTWSNG................
A0A810NDN0_9ACTN/19-239 ...................................................QMVVHVF.........APAGG...PHATTAYAALRDLWDACRHLFRL.DDAIPGLD...APARLPETAAdlp.......................dpaGTGPE.W..-.ILAGQERA...-DADYQAVLRRHHDLLNLSL..ALAPGPPPTdpap.......ahwpRWHDLDRQWSAL........AVGR.TA............................PLL.GVVRVYLAGM.............................TGLSDVGPAEippa...graaVGHALAGQLPGQA.......................--.P..RW................-AD.PAQLGDS....ALL.WELPYA......DDA..RWERRLLLAAPT..HDDATVSAWVWSDG................
A0A2I2KP68_9ACTN/26-242 ...................................................ELVVHLF.........TATQG...PRAADGYAALRAIWADCRERLGM.GHPVPGQD...LPTTLASTMPp...........................pWSTPE.G..-.VLAAQEKPdahTEEVRQAVLRRDHDLWCLSV..MVAPPPAAEp............plTWADLDIELWSM........RGVR.DD............................ALL.GTAWIYQGRWgvp.......................grvPRVSVPASAD...........TARRCVPSLPPAL.......................RT.G..SW................LTR.GTTTGQG....FGV.WETGRT......DDT..RRDRALLVLAAA..DDDEALSCWSWSR-p...............
A0A1S1QFF2_9ACTN/10-251 ..................................................v-LVVYLF.........APLGG...PGASDAFDHLRTVWDACRARLGM.DQAIGAIG...APDTLPDNLTgls.......................attGLPPT.G..R.VLSAQAGRd.aQAGRGEALLRLHHEVLSLTV..RLGPPAGAR...............GWRELDERWSTQ........TGPW.PPetitavpvggqkadpaewadpsigapdaALL.GSARAYLGLM.............................DDTDGQPVAAd........aaTARALLTSLPADI.......................G-.D..DW................VTR.GAATRSG....YAV.WELADC......PEG..RQRRRIVVIGPR..SRENGLSAWAWSRG................
A0A1S1R1R4_9ACTN/1-206 ..................................................m----HLF.........APAGG...PHAAETYGYLRRAWFACRDEFGM.RHPIPALD...LPRDPPERHR............................pEPGAI.D..E.FLAAQAHA...GEGVFQALLRRAHDVLCLSI..MLAPSPATS..............pSWVELQRRWVRA........CGPI.PG............................GLL.GAAEIYQARL.............................ADPETSHVEPa........hpLAAACRELLPAPT.......................-P.P..VW................FDNlGVATPQG....FAV.WEAERD......EEA..RARRRIVVLAPN..DRDDELSAWTWSRG................
A0A2T0STI2_9PSEU/10-201 ...................................................ELVVHLY.........VPSRG...EHADAAIGGVKAIWARCRDLLGA.TEPVPRVG...LPTTPPADV-.............................RGEPD.G..-.ALAAAQNG...-AVDVQVVLRRAGAVLALSL..IFAVPGTPGlga........aappGWIEFDRWCDEV........VGAD.AG............................SAL.GVVRVHQAKQ.............................PA--------...........--DDVRAWLPERL......................rDV.V..RW................---.--QRRRR....FLV.WEPV--......DDV..GRSRDLVVIAAE..GEDDELTAWTWSRG................
A0A1H1Y8E9_9ACTN/8-203 ...................................................ELVIHLF.........ARSEG...PSAVTAYAEIRAIWDRCRDVLGL.TVPLAGVG...LPTDLPTVLP.............................RDPGE.L..-.VVAARKHP...-GLLYQAILRRFPTTVNLSV..VLSPGPGGP...............GWRDLDRLWQSV........AGPW.SG............................TLL.GVAYLFLGKS.............................ADLTCTE---...........---RDAADLPVSG.......................-P.V..GW................WFH.GVPTADG....FAL.WEPGVH.....dADG..RAERRFLVLARP..DEDDRLADWTWSSG................
A0A5M3WCM8_9ACTN/8-218 ...................................................QMVVHLY.........APTDG...PYATRAYRALSEIWLGCRQVFGM.RDDVPGVG...LPEVLPSEWRaaf.......................dqaKIGSE.A..-.PIALQERR...-GADCQAVLRVHHDVLNLSV..ALAPAEDTAsmg........rdtsWWRRLDSEWAAI........SAAH.SR............................LFI.GESRIYLAKV.............................RPSVDAS---...........LPGHLAESLPDDG.......................EP.V..NW................-DY.PIVTSDG....LTL.WEPQRG......RDD..RTLRRLVLAFPP..ENAAQASAWTWSDG................
A0A8J4DTL3_9ACTN/7-214 ................................................dfi---GHVF.........AQDT-...---PAGHLLVRKIWTRCCSVMRL.WYPMSGVA...IEREMPAEHR.............................-PAAA.S..G.EICAAESL...-KMGVQAIVRRHEGSLLLSL..ISDTDATDStds.........gsgPWAAVDDRWTRI........VGVD.AD............................DLM.GEARAYLTQI.............................EDP-VDSLAT...........AARELAPLVPGTAn....................gfDA.Q.aGR................-KN.LDEAGGGg..nVFM.CETGPA......GAA..ASARRLLLLGRP..VDAAELLSFAWGDG................
A0A1H9JCD7_9ACTN/6-228 ...................................................ALGVHLF.........VLTGG...AHRDGALALLAEVWDKCGTVLGM.TDPVERTG...VAVQPESGWEsl........................igtTATGT.A..G.LLAARARP...GVGVRQAALRRERDVLCLSV..MLAPAAEEG..............lGWAELDTQWSAVlpagdaleGRPR.GR............................GVL.GVARLYLARL.............................AEPGVRPVPEpd.......rpLAVAVQARTPADP......................aVS.D..GW................PYG.GVAVSRG....FAV.WEASAA......RDA..RLERRFVVVAAH..DHDRELTAWTWTT-r...............
A0A0D0VYV8_9ACTN/10-229 ...................................................ELVAHVF.........VPLTG...PHHPHGHAHLAQVWRRCRELLAI.VEPTP-LG...LPTDLPGDVD.............................DLPAR.D..G.PVAAARRN...GGGVHEMFAYRRHDMLCLSV..VLAPGQAT-...............SWPALEADWARA........RGGE.HP............................AVL.GEVRLRLARH.............................RRSRWGSASAt........aqAYASLRAALDGPDrpg.................paqG-.-..-Asgrrl.....ppgadrPSP.GVAVTPG...gFVV.WEASGL......PDD..RRLRRLVVVAPK..GADEQLSEWVWSSG................
A0A7W5YUH3_9ACTN/5-191 ...................................................ALVVHVF.........APVSG...CGE-----QLTALWERLGEGLGM.TWSIPELG...-PYRLD--L-.............................DEPPR.G..P.VLAARRSR..sREEIVEAVVRRRHDALALTV..GMSPPARDG..............vDWRELEERWTRT........ADDL.PA............................WAL.GEARLFTGVA.............................PDLTAPPS--...........---EAPHGFPLSQ.......................LE.-..G-................--T.ALLVDGH....TAV.WEQQG-......ADD..RLTRRLLVISAV..RRQDDSEAWMWTPG................
A0A5M3XYX8_9ACTN/2-121 ..........................................tarigcysr-------.........-----...-----------------------.--------...----------.............................-----.-..-.--------...--------------------..--------S...............GWAEFDRRWNEI........ANDA.LD............................PLL.GVARLYLARV.............................HSDNAAKAHPs........adLAAAIRPLLPFAT.......................HD.S..DW................WKR.AFRADGG....LAL.WEPSPF......EDA..RIERRIIVVAAE..NHDAALSAWTWSRG................
A0A1G7XDB7_PSEOR/8-206 ...................................................ELVAHIL.........VPVDG...PVPAES--VIGPVWEQCVEEYGL.RESIADH-...-PTELPADLG.............................EAPEE.V..-.PLAARRLS...GDGVQDLVLRRMHDVLCLSF..VCAPNGPA-...............DWPVLHTRWGRV........RAAC.PP............................SVL.GTAEILQARH.............................AAKA------...........DPDQLGTPPPLRG.......................--.L..RW................-SA.GVRRQPPelgpFAV.WEANPDgadralVRS..RTHRTFAVVAPK..EADSQLSRWTWRR-e...............
K0K976_SACES/8-193 ...................................................ELVVHLY.........APEES...GGA----EQLSRLWARLADVLGL.DRTIAGTG...LPLFPSAED-.............................-RA-P.G..T.VLAARTDG...--RGRQALFRRLGKALNISL..LIPVGAG--...............GWAAQLAEWESV........RSDL.-D............................QVT.TEARVFIGTA.............................PGSATLPIGE...........VAAAVAHRLPLTW.......................--.P..RA................PLD.SAARQSG....IVV.VTRGP-......-GI..RVTRDLVVLA--..EDEELLSWWTW---glg.............
A0A6M1L7X5_9ACTN/6-191 lhvynyldtgphrdvlaslvaacrtlgianlsevaearpsrqsarrlfssp-------.........-----...-----------------------.--------...----------.............................-----.-..-.------TP...-GLIFEALEYVTARVAAFLV..CLAADDDSG...............TWREFDRDWRNA........FGRP.QD...........................sGYS.GRVRLFYGLY.............................DGDGDPDR--...........LAGIVAAALPDGL.......................GS.-..-L................QAA.PTVLFEG....CYL.WEVGGA.....aEPH..RLERVMVLLAPA..DRECDSDRLVWPH-g...............
A0A7M2T6A0_STRCW/11-230 ...................................................ALQIHCF.........LDIP-...RFQADGHARLAGLWQACH-RLGM.DQPLSPAP...-NLALPPAIE.............................GSPGF.R..R.QMA-RKRQ...GPGVYEAMLYTYGNTLGLAV..ILAPPETGAshta......mqtaaVWTELNDAWDRA........CAPS.PSgt........................rdPLL.GTVRIHRALV.............................EPAAGTPRTDd.........eVGQQLALRLSGTS......................aSN.P..ET................LSE.RVTLGPG....LSL.WEATSAq....aDPV..GRDRRFLTTAAAtdDQEELLDGWVWTDG................
A0A1X7C7J5_9ACTN/12-224 ...................................................ELVVHVY.........APTDG...PHAKTAHRQLQGIWDHCRDRLGM.VREIAATG...LPAVLPSGP-.............................DAMTP.G..R.PVAAIEDR...-AADHQAVVRREHDVVNLSL..VFAAPQDTAsrrlri...gsasppGWVEFDRWWGEL........AADG.TD............................ALL.GVVQVCQALY.............................AAGSAPSLDG...........LAHEARSVLTGAG.......................RT.P..DR................WRR.GFTTAEG....FAV.WEVTP-......DDE..RAGRRIVVLAPE..GREAELSAWTWSQG................
A0A4R2JHB5_9PSEU/9-214 ...................................................ALLVYGY.........HPLD-...-PASDAWAEFVALWNALG----I.TGPVVNLD...APATLPGMSP.............................ETRET.S..E.LLAVASAG..eLPEVWQLVARIEHDTVCLAA..MMAPARELDc............sgEWKALERRWLSA........ASPY.SS............................TLF.GEVRIFLALT.............................GDEADAD--G...........VETEVRTAIPEPW.......................-A.V..RWhtr..........hddVTL.PGTEHDT....LRV.WEAGPL.....tSDG..RPVRRLAAVGAA..RHEGTIDSLVWSSG................
A0A5M3VZH2_9ACTN/7-241 ..................................................s-LVVHLF.........TQHT-...-----DYPRLRTLWADCVHTFAL.TEPHPRPN...IPTDPLADQN.............................TLPAT.G..-.PLAARHSP...-QNETQAVIRSHHDVLVLSL..AFSPPEPHSp.............dAWADLETQWTRV........AGNT.TD............................WAI.GETRLRLAYEttapygidvgkpsrvgednppsagdngprS---------...........VGEAASSALDESGgtd.................epsD-.-..-Aaeavla....aveeneSSG.TDAAAHG...lYAVyREVGEP......SDT..RRLRTIEVVAPV..AFGVESDHRTWSR-r...............
A0A1I0BYY8_9ACTN/7-249 ...................................................QLVVHLY.........APADG...PGAAAAYRDLRQVWLGCR-LLGM.RDPVPGLG...LPHMLPETLTdlpagpsaglpagpsaglpagtsagppagVLVGA.E..A.PLAAAEAR...-GADRQVILRRHHDVLNLSV..ALAGPSSAVd............gpGWAALEDDWNAL........VSPC.SR............................HLI.GETRLYLARL.............................EQAPPGE-GPpdlaa.pdlaaPDLALAGLLPAAA.......................QA.G..DW................WNH.GVVVPRD....LAF.WETTTT......PDD..RALRRFVLAFTA..DREDEASAWAWSRG................
A0A4R4XPL7_9ACTN/10-182 ..................................................g-LVVHVF.........VARSG...PSAQEHAERLGGLWSALGSRLGM.TVESGG--...----------.............................-----.-..-.AVSVREAP...EGPLRQGVLRDVHDLRCLGV..ALTGG----...............TWRELAELWEGC........AGDL.G-............................WVL.GECRLFVDYE.............................RG---QPARG...........LTRSVLPALPGAE.......................--.-..--................REY.RFTRANR....FAV.WETGLR.....dGNA..RRLRVFAVIADV..ERERDLDAWLWSSG................
A0A4R1DVC6_9ACTN/10-215 ...................................................ALIVHTF.........ASLARv.aEDEESGINSVGQMWSRMCDRLGM.SDPVPHYGsadLPALAPLAQS.............................LPANG.C..R.LLAARQCT...GSRPAQAFAYVRHDVIGITV..VLFPTPNV-...............SWRDLRSRWEAA........APAL.PE...........................qTVL.GTAYIYRALD.............................GRRAGHGTG-...........GLRRLLSTVPSPAa.....................sL-.D.gTW................---.-RRTSDS....YLI.LCSDPP......GPA..PFVWEAVAVGPA..AREDAFDAWTWH--vh..............
A0A7K1KTA6_9ACTN/10-197 ...................................................ELVAHVF.........APLDG...PASAAALTALRRIWERCADVLGM.TEPVPSTG...LRDTVPPSLK.............................RVP-N.G..-.AVAAREHR...-DHDLQMVLRREHDVLHLVL..VSAAPRGGTp............gpGWADHERLLGRV........LGPT.-D............................VFI.GTALLALGKT.............................TGN-------...........-------GVPPEE.......................-A.P..GW................SRQ.PARLPGG....IVA.WEYGPA......AQP..TADRRIRVLGAP..DQDDLLSAWTWSRG................
A0A7K2ZQE5_9ACTN/5-142 .................................................ea--AVHVF.........VPLDG...TRTEEGVASLAAMWDRFRELQRA.DRQLYPA-...LPVRMPDVLP.............................GRASY.G..S.IAVAGAQS...ADRLDQAILRRHRDILNLSV..LLGAGPGR-...............EWPGLRERLEAI........TGPL.GE............................CHL.GSVTMELGKA.............................PAETPGAAD-...........-------------.......................--.-..--................---.-------....---.------......---..------------..--------------vme.............
A0A8J3HP52_9ACTN/10-217 ...................................................QLVVHLY.........APTDG...PAAEAAYRRLHEVWAGCRHAFAM.TEAIPGTG...LPSHLPETLGel.........................igAGSGQ.E..R.AVAGQEHR...-GAVDQAVLRLHHDVLCLSV..GLAPARPETg.............tWWARTDLRWREL........VGSA.GP............................SLL.GQAMVYGARL.............................DGPVSASAE-...........EGQQARLLLPARA.......................EA.A..DW................WQR.GCLLPDG....VAM.WEITPQ......EDS..RDLRRLLCAVPE..PDDAQLSAWIWSDG................
A0A4R1HJ22_PSEEN/11-218 ...................................................ELVTHVF.........VAATG...DAAADQ-DRATRLWAGLDGTLDR.RTAIGHH-...-PTEVLEGA-.............................RPGPD.G..-.VLAAAKAS...GPAVHQALLRRENDMIWLAT..VRAVAPGEP..............gTWPDLESDWDRF........DGPR.GD............................AVI.GSVRILQART.............................DRPGVAPDPV..........eLSDAVRAATGIDG.......................--.-..AW................ADT.GIAWTDAqlgsFAV.WEAPPAgppphdPDG..RTHRRLVVVAAH..DRDPQLSAWTWTRG................
A0A8J4DVC9_9ACTN/9-209 ...................................................ALLAHAF.........FTADG..tSPSEGGRADLRRLWDGIV-GLAL.DSQIPGM-...-PATLQDAVT............................gGFTGR.L..T.VLGARRSA...-DGADQLVVYQDHDIVGASL..LLAPDPPGA...............TWIGLQRRWEAAl......dGAPV.AR............................AAI.GSAVVYIGQT.............................DIEVPAHN--...........TLQQLVPLLPAAE.......................GM.-..--................SPA.TAGFHRG....IRL.GELPPSg....dGPV..ACHRRLVAVAPP..AEKDTLDRWLWSD-d...............
A0A7W7MCH4_9ACTN/10-214 ...................................................ELVAHLY.........APLDG...PDAATALRWIGRFWERCRTQLGM.TDPILGAD...LAAGLPADP-.............................AAEPE.G..-.ALAGLQDP...-AVRFQVIARREHDVLNLSF..AIASPAAVVrdrpri...gaavppGWHEYTRWWDKL........GGAE.PS............................GLL.GGALVYLAKA.............................ADP-------...........AAAEVRAAVPSRP.......................DDgA..GW................WSR.RGALDD-....FAA.WETTP-......AGS..RPDRRLVLIGAM..DQDEPLSRFAWSDG................
A0A841BUK7_9ACTN/7-222 ..................................................t-LVVYLF.........AAVTGedpARATASYQQLRQAWHTIADRLHL.DTAA-STR...LPADPREKAP.............................TTTGT.A..-.LQAGREGP...-GRLRQMWWNQFHDVAVISL..AISADGISEe.............rGWHALHSEWADV........AADLvLP............................TLL.GSTQVYTARTatnep...................livspTDGAPDKP-A...........TTAQLGPYLPGIP.......................A-.S..GW................ADS.ATLVRTG...gFVI.YELSPR......AGL..QPDRQLVVLAPH..DRDDELGSWVWQ--ls..............
A0A7K2YF25_9ACTN/1-199 ...................................................-----MF.........VAADG...EDSVADLAYLHRMWRACGDVLGM.TEPVPGM-...-NADLGPAW-.............................AQAPP.G..-.LSAARSRP...-GGMHQVVLRREYDTFCLSA..VLEPDTVEG..............vTWSELDARWSRVe.....raAGAA.PS............................GVL.GSARLFLARL.............................TDPATPVRA-...........CPESVQDSVPTDG.......................SG.T..GV................RSGpGALLGGR....VAV.WESCGP......GDD..RTVRRLAVIAGP..DGDAELSALAWV--vag.............
A0A2T0RCI2_9ACTN/119-304 ...................................................ELVVHAF.........APMDG...PWAEPAYQQIRRLWNRAAQALAA.TGALGEP-...---ELPADGL.............................RLPAG.P..-.LLAGRQRP...-DQAAQMVLRREHDALVLSI..GWRAMPDNA..............tGWDEWERQWERI........AQDD.TG............................ELL.GVARLRLGFA.............................PP--------...........--DGVGGLLTGEL.......................--.-..-W................ESG.GTALATA....GTL.WELPPY.....dAHD..RLQRSLLAVAPD..EQEAALSALVWSD-r...............
A0A4U3MJM4_9ACTN/7-171 ...................................................QFVVHLY.........ATLET...APA------FRQLWAECRKVFGL.TEKV--LD...LPIEVPASRG.............................YPAGA.E..A.ALAGA---...GRGDSQGIVRIHHDMLVLSV..GLTGG----...............DWQTWDANWSGV........VSHR.--............................DFL.GEARLFLAHG.............................----------...........--GGVRSE-----.......................--.P..HW................-LG.PVTTPDG....LAI.WERGGD......VDY..RRTRRFLIAF--..EDDPVASAFVWSRG................
A0A543C0Q5_9ACTN/8-204 ...................................................ELVAHAF.........ALLSG...PTQASAEAAVRALWDGCGSHLST.TEEVARTG...LPARIPTTLP............................sGRLGG.Y..V.PVAACQDA...-DRRVEVILRRTGDILVLSV..LLTDGPTA-...............TWTGLDAKLDTV........LDGA.--............................ALL.GVARLYLGTT.............................TGAAGPELGR...........DAAELLGATEEVG.......................--.-..QW................WHH.GVTVSGG....LAL.WDARPR......-DD..GRERRLVVLAPP..GAQDELGRCAWA--vp..............
A0A545APA1_9ACTN/10-220 ...................................................ELVAHLY.........APLDG...PHADTAYQQISAIWKRCRSELNM.TLSIPGTD...LPTDLPEK--.............................-FTRE.G..S.ALAGLQDR...-VADYQAIVRHEHEVLNLSL..VFATPVADHdrkpri...gaaaplGWREYARWWRQL........TANG.LD............................ALL.GSVVIFQAKR.............................PEESTDYVS-...........WGADAGAVLPPGP......................tDE.P..GW................RQR.PTNAGE-....FAL.WEVAPA......DDD..GGDRRLVVLAEP..GRDRQLSDFTWSSG................
A0A010YLS5_9ACTN/132-171 .................................................ld-------.........-----...-----------------------.--------...----------.............................-----.-..-.--------...--------------------..---------...............------------........----.--............................---.----------.............................----------...........-------------.......................--.-..--................---.------G....VAT.TELDG-......PED..RSERRFQVLAGP..ADDERLSAWTWSDG................
A0A4R6J9T8_9ACTN/10-207 ...................................................EFVAHVF.........APLDG...PDSDAAQARVRALWVNCRDQLGM.DRPIVEVG...LPAVLPPGF-.............................GDGAD.R..-.AVAATEDA...-AAQFQMIARVEHDLLNVSF..AAASGSRPSlst........papvGWHEFSRWWATL........GGEA.--............................PML.GSVIVLLAKA.............................RDL-------...........TGPQVRTEVPVRD.......................DDgD..RW................WES.GFRLDD-....FAA.WETGA-......PGP..AAARRLVLLGAP..DQDAELSRFVWSDG................
A0A438M8U0_9ACTN/10-182 ..................................................g-LIVHMF.........ATATG...PEAGEHERRLRGIWDALGDRLEM.--PVTQAG...----------.............................-----.-..-.KIEVRTAD...GDLGRQALLRRERDVRCLSV..ALTGG----...............TWRELNELWREC........AGDT.GA............................WAM.GECRLFVA-Y.............................PRTAPTAR--...........RTNAVLAALPEPC.......................--.-..--................PRG.RMTTVRG....VAV.WEVGFD......DDE..RSRRTFAMLTPP..ELEPKLDAWAWTRG................
A0A7X0IC25_9ACTN/10-222 ...................................................QFVTHLY.........APGSG...PDAGPAYRALRDIWSGCRQVFQM.VDPVPGLR...LRHLLPDSYDdl........................ppvTWSGP.E..A.ALAVQEQT...-GARCQAVLRRHHNILNLSV..ALAPTPLMPspd........gprsWWRELDRQWTRL........TATQ.AP............................HLL.GEARLYLADL.............................AAPPPDHTM-...........TGRELGPLVPGDQ.......................A-.E..NW................WRR.GVTHEER....TTI.WETSPS......DDG..QWLRRFLVAFAT..ADAKAASAWTWSHG................
A0A810NBD0_9ACTN/1-176 ..................................................m----HVF.........LPVTG...PDRHTALPWVHHVWRRCAEVAGM.DQAVAAL-...-PAAPPDALA.............................DLPTG.S..R.PVAACTGP...GPGVHQALLYREHDLLCLSV..VLAPDPPT-...............GWEASERLWERLv......gGGPV.AA............................PTI.GEARLFLATG.............................----------...........-------EWPPTP.......................--.-..--................--Q.AAVTRTG....FRV.WEESAL......DDQ..RQVRRLFAVAPA..GHTVRLSDWTWTG-g...............
A0A2S6GT20_9PSEU/8-200 ...................................................ELVVHLY.........APVDG...PRAAAGWVALREVWSRCGRLLGT.TDPITETG...LPTAFPDTP-.............................---GQ.A..-.AMAAAEGR...-GGDFQVVLRRYHEEVNLSV..AMAPADA--...............GWVEAHRWWAEV........RADA.TE............................PLT.AEVVVSQGRV.............................AELARTAPAE...........VAAAALLALPRDA.......................RR.A..RW................-PE.AAAHGTG....FLV.WEPD--......ATV..LPDRHLVVVADE..TQDRDLSTWTWSDG................
A0A6F8YXY0_9ACTN/109-313 ...................................................ELVVHAF.........APLDG...PGRDPAYRQIRRMWTAARTLLRA.SDAIDGG-...-PTDLPAECA.............................RLAVG.P..-.VVAAQQRA...-DRRVQVVLRREHDVLNLSIgwLADPGAPPR...............TWAQWERQWDAV........AAGG.TD............................ELI.GVVRLYVGFQ.............................PAGRRGGPPArp......pveVAAELAAGLTPDG.......................GT.-..LW................-NG.GV-LVDG....CVL.WELPPF.....gEHA..RPERRILALGTP..ERERELSDLAWWRG................
A0A429FKE3_9ACTN/27-229 ...................................................ELVVHLF.........APAEG...PRAPHAHRALRDLWEGARHLFRM.HDPIPGTG...LPRDLPDP--.............................ASGGD.G..-.PLAAQENP...-DDDYQAVYRRHHDAFVLSA..ALAPRHGAAgpd.........gggGWRDLDRWWSAL........AAGR.TA............................DLL.GEARAYLATG.............................PGLAAPSDA-...........DAARLVPLLPDGP.......................--.-..RR................PRGpGAAVRER....VGV.WDVSAG......DDD..RARRDLLIVADA..ADEAELSALAWSAG................
A0A1S1QF37_9ACTN/108-315 ...................................................ELVVHLF.........APADG...PRAEAAYAHLLSVWERCRDHLGM.RHPAPGLR...LATRPPAALG.............................--RAT.G..-.DLAAVDGG...GEGVYQALLRRDHDLVRLSA..VLAPAAGAGa.............fDWTPLDALWSRA........VGPL.ST............................DLV.GAVRIYQGHV.............................RRRADDGQVTvs.......eaLARGCRHALPPSE......................gGR.P..GW................EER.GVTTGSG....FGV.WELGEG......DDL..RIERQIVVLAAA..ERDHALSAYTWTR-t...............
A0A239ISV6_9ACTN/8-222 ..................................................s-LIITCF.........VPATP..eAEDTAAHAYLARLWDACG-LLGI.TEAFGGLP...SREEPAPESD.............................AVAAE.F..T.ILEAATRE..dGPGIHAAFRFAEHDVRGLVA..LLAPNDLDTg............lgQWNTLLDQWSTAlta..agvTDPP.PD............................GIL.GEFRVFTALH.............................PAGTPRSQPP...........VAESVRRHAPPSG......................aDD.D..TW................WRG.HDVTEHG....FSV.WRTGPG......DPR..DVVTDFCVLAPL..RAEGALDEWVWAR-e...............
A0A1S1QG02_9ACTN/4-216 ...................................................ALVVYLF.........APLGG...PGAQTAYEYLRVVWEACRSKLHM.DRPIKKLS...AGSTLPGSLTgle.......................tvtGLPPT.G..S.VLAAQAGRd.pEAGRGEALLRLHHEMISLAV..RLGPPVQEH...............DWRYLDARWATV........GGPP.PPav........................ddALL.GRAYVYLGHT.............................-GILDGPAA-...........VARRLLPSLPAVA.......................-S.D..DW................ADR.GAATRSG....HVV.WEFADF......PDA..RVTRQIVAVAAR..GRDTALSAWLWSRG................
A0A1C4RG02_9ACTN/10-215 ...................................................ALIVHTF.........VPLAAa.vRDEVGGELSVRRLWERLGDRLGV.TDPVSGFGpaeLPALAPPTAA.............................GSAAG.H..A.LLAAGQCT...GPSPAQAFAYRRGDAIGITV..VLFPGPGV-...............SWGDLCRRWEGV........-APL.PE............................RLGsSTTYVHRVLV.............................SGRTPPGAG-...........RLDRLLTSVPAAGv.....................sAP.PegNW................---.-RRSPDG....YLV.RLARS-......AGP..GAVSTAVVVGPA..SREADFDAWLWHI-g...............
A0A516RIQ3_STRST/8-205 ...................................................ALLLHVF.........YGVDR...AGLGARVPQVQRVWDDCG-RLGL.HAAVPGEA...LLDEVPAIG-.............................GPAPR.Y..R.VLAARQQM...GGGLRQALLFQAHDVVGITL..LLAPEQES-...............GWESLERLVSWA........----.CP............................GSL.GSVQVLLGLG.............................AGALFAADGGdvv.....vpeVAGEVGGLFPGRR.......................--.-..--................PGA.PHRTRQG....FAL.WEVPGA......VAP..AVRRRFVALAPV..ARERQLDAFAWHA-r...............
A0A841C463_9ACTN/10-190 ...................................................ELVVHAY.........APLDG...PAAAPAYAQLRAVWTAARQLFGA.DRTIAGTG...LPASLPDDP-.............................GSTPD.G..-.ALAGQETL...-VSDCQLILRRSHDTLALSL..AFAETRDT-...............GWADFDRRWTEA........TRAG.TD............................SLL.GIVQLFLACS.............................SNQ-------...........------TDSPGAE.......................--.-..-W................-RH.PTRIEP-....FTV.WDSDSG......TRA..TPSRRLAILAPA..AELDALSAWAWSRG................
A0A841D6H7_PLAVE/8-194 ...................................................ALLVHAF.........TAVG-...DDGDSWREPVRRLWQIFLDLGEA.RAISPHTA...--LDVPAEL-.............................PPAGR.F..T.VLTAAEIP...GRGTYQAVLYREHDVIGLMV..MLAAEEAK-...............GWDFLDGQWPHE........----.AS............................GGL.GTARIHLGVT.............................VP---RRL--...........RLRRTRDVLPDRL.......................GPgP..VW................---.---SRGG....ITV.RELPSAr....aPRR..PATRRLVVLAEP..GDEEEMYTWTWSSG................
A0A4U3MG16_9ACTN/7-204 ..................................................q-FVVHTY.........LADH-...-------AATLDLWHGAAHEFGL.DQPVGPI-...LPQTPQVSSTdl........................sgaVPTGP.E..T.ALAARGQA...-GTSCQMILRRHHNVLVLSV..GLALPGGP-...............GWQGWDRRWTTL........TAGH.RP............................GLI.GEDRLYLAGV.............................ADGDPTWGPE...........FGWRAGALLPMEV.......................PV.E..RW................WES.GIGASPD....LGI.WELAAS......RDD..RARRRFVVGFPA..TADARTSALVWSRG................
A0A428YTD4_9ACTN/5-209 ................................................sya---MHVY.........TYLDG...EDGVAA---LQELVEICG-ALGMpESPIEGTR...GARTS-----.............................GPEAR.R..S.FGGASER-...--KIYQAIEYHTTRLTAFLA..CLVPADGR-...............VWAQLDREWREA........AGTA.PA...........................aDCV.GRVHLYYALY.............................EGGS--GVER...........LAGLASQALPAPGlle.................rrtD-.-..-Pairgh.....hadpvnLKH.RTELFPG....CHL.WEVNPG......ADG..GRDRVFALLSPA..NQEQRSDDWVWPA-g...............
A0A2B8AVU4_9ACTN/6-216 ...................................................ALGVHVF.........VVTGG...EHRAAALAFVRALWVQCGARLGI.TEPVPGVG...VGMEPRGGW-.............................AAHTR.G..-.LLAVRSAT...GPGVRQAVLRRDHDVLCLSV..MLAPDAAEN..............lRWAELDAQWSGVvra.agpgAAAP.NS............................GTL.GEARLYLARL.............................VDPDARPTAEpt.......gaLVATVRSRAPGAP.......................--.-..DR................VPD.GVVTPQG....FAV.WELSPT......ADT..RIVRRWVTVAGH..ERDPELTAWAWTD-r...............
W7ST62_9PSEU/10-203 ...................................................ELIAHFY.........AFHDG...EDAE-----IRTLWSRCGEVLGA.VEPITSTG...LPVALPDTL-.............................--PNT.S..A.LVAARWDP...-GTRLQAIMRMEHEVVNVSL..LFRYRIEH-...............TWRDFDHVLDAL........TGTP.AG............................PLL.GSARLYVGLL.............................ADGGPGELAA...........TGRAVAELLPAAA.......................GT.A..GW................WHE.GLRLDND....LLL.WETGET......EDD..RVQRRLMVLAAP..GHGATLSAWTWSDG................
A0A840NXD4_9ACTN/19-213 ..................................................a-MAVYLY.........APVDG...PHAEECWSGIRSLWHSLA-----.--EGRRAG...LPSRPG----.............................DVRAD.GvcA.ALAGAS--...HPLIRQMALWRRHDVVCAGV..LLAPREQDAdvp.........grtDWAALEAAWTGL........CAGI.P-............................HLL.GEARVLMAVL.............................RA--PRGPG-...........ATRALRRAVPPPA.......................-P.P..GW................WTR.RDTVAPG....FAL.WEASPS.....gDDG..RPLRRLVVTCPP..RHQARLSRWTWR--ga..............
C7PYD7_CATAD/15-225 ...................................................ALAVHVF.........FSAEG...EHARASYARLRDLWTACGDSLGM.TTPVPRLG...MPVELPPTLA.............................APSVL.G..-.PAAARQSV...AEGIVQAFVVRERDVYCLAV..MIAPDAAER..............lGWSELEARWSAVvtagasagAGTP.NA............................VPL.GEARLFLALV.............................-NTMPDGVA-...........APSGVREAMPQHP.......................DT.D.eAW................WRR.GHRTDSG....LLL.WETASR......PDD..RAVRRFAVVASR..RDEKLMDAWVWTRG................
A0A8J4DSW8_9ACTN/10-205 ...................................................ELVVHLY.........APLDG...PHADAAYGELLQIWERCRTNLGT.TEAVPGLA...IDDRLPPTRRdl.........................pgGKVDT.E..R.EIAAQRHP...-DRPHEVILRRHHDVLNLSV..ALGGDA---...............PWDSSQRRWEDV........LGPW.SG............................ALL.GEDRVLCGHT.............................EV--------...........PVADLGDELPHRD.......................EH.V..YR................WRE.GAVGPHG....ITV.LEVARL......PET..RARRTLVALAPP..GREDALSALVWSDG................
C7PYD3_CATAD/9-236 ...................................................QYVVHLY.........APATG...PEAPAAYRGLCEIWRGCRLAFQM.TEAVEGFD...VPQVPPSAAE.............................GVPEEfE..G.VLALQERP...-FADSQAVLRKHHDVFNLSV..ALAPPETRLpke........gewtWWRDFDRTWNAI........SARY.AP............................HML.GQARLFLAGV.............................PEADPADAS-...........LLGWLATLVPTDAtd...................atD-.-..-AtdaadstsstasntepPDLlGATLDRG....VQL.WEPFAR......PLY..TPDRRLLLAVGP..GSDARASRWIWSSG................
K0K3J1_SACES/6-200 ...................................................ELVVHAF.........APSTG...RPARRGRQWVQETWQRCQDLLGT.AEPIAPTG...LPGTPPAAL-.............................DRGPD.G..-.PLAAAQNT...-AVDAQLVLRRAHDVLNLSL..LLVSPSAEGlga........gvppGWIEFDRWWAEI........AGDV.G-............................VLL.GVTRVYQAKL.............................PV--------...........--GEVRPHLPTHL......................rDT.V..RW................-DR.PYRWDDD....VTL.WEPD--......LTV..GPVRDIVAFAPP..DKDPELSACTWSRG................
A0A0M8UWR4_9ACTN/25-215 ...................................................ALVAHTF.........FRAD-...RQAAAAWGSL---WEAVG-RLGL.DEPIGRR-...-PVELRSVDG.............................VGGHH.L..D.LLAARRRV..vPGAVYEALAYRSHDVVGISL..LLAPNDDEV...............GWGDLAEQW---........AVPL.PA............................QAL.GGAMVFLGLR.............................GDRSWRRWRGta.......rwDHSEVSRYLPGRP.......................DV.D..GW................---.-CRAGNG....LHL.GELPPG......---..-ETRRLVLMGQI..RDEAAMDRWTWLT-d...............
A0A841BFR8_9ACTN/20-188 ...........................................qdayrrav-------.........-----...-----------------------.GDAVTGLG...MV-EVQAPTA.............................AAPPD.G..-.FVGLHAAP...GGGILEALQYRDGDLTAHSV..CLAPDPAVAd.............aSWSVLDRRWRDL.......gTDPA.PQ............................ACM.LEARVLYALY.............................GGGPPDA---...........--VAIAGLLPAEV.......................GP.L..-R................-PA.AADLGDG....IRV.WATGS-......-PH..DALRYLVVVAPR..DHEAEADGWLWPDG................
D3D729_9ACTN/8-216 ...................................................QFVAHVY.........LPLDG...PGAAAAYRALREIWRGCRGLFAM.TEPIAGLS...LPPDLPADPGq...........................lRVGAE.I..-.ALAAQERP...-AGECQAIVRRHHEVLNLSV..ALTSSSSGR..............sWWAEGDRLWHAL........AAEH.MP............................HML.GETRLFLARL.............................DTEAVPAVREad.......ptLFQELTAALPADA.......................--.R..GWp..............gARR.GVTVAST....VAV.WETTPE......PDE..RSRRDWLLAFGP..DSDAAASALAWSRG................
#=GC seq_cons ...................................................tLllHlF.........sshsG...stussuhttlpplWptCtphLuh.scslsshs...lPsphPssh..............................shssp.t....slAAppps....ssshQAlLRRcHDllsLSl..hLusssst................sWscL-ppWspl........sush.ss............................slL.GpsRlaluth.............................ss.ss.t..............hsttltstlPsss.......................t.....tW.................pp.sstsssG....hsl.WEssst......scs..RspRRllllAss..sc-spLouWsWop.................
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