#=GF ID CNDH2_N
#=GF AC PF06278.15
#=GF DE Condensin II complex subunit CAP-H2 or CNDH2, N-terminal
#=GF PI DUF1032;
#=GF AU Moxon SJ;0000-0003-4644-1816
#=GF SE Pfam-B_11729 (release 9.0)
#=GF GA 32.30 32.30;
#=GF TC 32.30 32.40;
#=GF NC 32.20 32.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 20442714
#=GF RT Condensin and cohesin complexity: the expanding repertoire of
#=GF RT functions.
#=GF RA Wood AJ, Severson AF, Meyer BJ;
#=GF RL Nat Rev Genet. 2010;11:391-404.
#=GF RN [2]
#=GF RM 22855829
#=GF RT Condensins: universal organizers of chromosomes with diverse
#=GF RT functions.
#=GF RA Hirano T;
#=GF RL Genes Dev. 2012;26:1659-1678.
#=GF DR INTERPRO; IPR009378;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC CNDH2_N is the N-terminal domain of the H2 subunit of the
#=GF CC condensing II complex, found in eukaryotes but not in fungi.
#=GF CC Eukaryotes carry at least two condensin complexes, I and II,
#=GF CC each made up of five subunits. The functions of the two
#=GF CC complexes are collaborative but non-overlapping. CI appears to
#=GF CC be functional in G2 phase in the cytoplasm beginning the process
#=GF CC of chromosomal lateral compaction while the CII is concentrated
#=GF CC in the nucleus, possibly to counteract the activity of cohesion
#=GF CC at this stage. In prophase, CII contributes to axial shortening
#=GF CC of chromatids while CI continues to bring about lateral
#=GF CC chromatid compaction, during which time the sister chromatids
#=GF CC are joined centrally by cohesins. There appears to be just one
#=GF CC condensin complex in fungi. CI and CII each contain SMC2 and
#=GF CC SMC4 (structural maintenance of chromosomes) subunits, then CI
#=GF CC has non-SMC CAP-D2 (CND1), CAP-G (CND3), and CAP-H (CND2). CII
#=GF CC has, in addition to the two SMCs, CAP-D3, CAPG2 and CAP-H2. All
#=GF CC four of the CAP-D and CAP-G subunits have degenerate HEAT
#=GF CC repeats, whereas the CAP-H are kleisins or SMC-interacting
#=GF CC proteins (ie they bind directly to the SMC subunits in the
#=GF CC complex). The SMC molecules are each long with a small
#=GF CC hinge-like knob at the free end of a longish strand,
#=GF CC articulating with each other at the hinge. Each strand ends in a
#=GF CC knob-like head that binds to one or other end of the CAP-H
#=GF CC subunit. The HEAT-repeat containing D and G subunits bind
#=GF CC side-by-side between the ends of the H subunit. Activity of the
#=GF CC various parts of the complex seem to be triggered by extensive
#=GF CC phosphorylations, eg, entry of the complex, in Sch.pombe, into
#=GF CC the nucleus during mitosis is promoted by Cdk1 phosphorylation
#=GF CC of SMC4/Cut3; and it has been shown that Cdk1 phosphorylates
#=GF CC CAP-D3 at Thr1415 in He-La cells thus promoting early stage
#=GF CC chromosomal condensation by CII.
#=GF SQ 1211
#=GS A0A1S3Z2T0_TOBAC/10-128 AC A0A1S3Z2T0.1
#=GS A0A444TZI6_ACIRT/59-143 AC A0A444TZI6.1
#=GS A0A7L0TDC8_PODPO/6-123 AC A0A7L0TDC8.1
#=GS A0A6G1B534_CROCR/1-90 AC A0A6G1B534.1
#=GS A0A8K0CI24_9COLE/18-140 AC A0A8K0CI24.1
#=GS A0A8C2W440_CHILA/6-125 AC A0A8C2W440.1
#=GS A0A8U0VAD9_MUSPF/1-75 AC A0A8U0VAD9.1
#=GS A0A7J7QUS0_MYOMY/79-136 AC A0A7J7QUS0.1
#=GS A0A7T8GQK4_CALRO/7-114 AC A0A7T8GQK4.1
#=GS A0A4S8JQR3_MUSBA/16-136 AC A0A4S8JQR3.1
#=GS A0A5J5N9S6_MUNRE/51-110 AC A0A5J5N9S6.1
#=GS A0A1V4K4H6_PATFA/6-122 AC A0A1V4K4H6.1
#=GS A0A8B9CVM3_9AVES/6-122 AC A0A8B9CVM3.1
#=GS A0A5N4DHE0_CAMDR/35-153 AC A0A5N4DHE0.1
#=GS A0A6P5A4V8_BRABE/12-130 AC A0A6P5A4V8.1
#=GS M4DXF1_BRARP/8-125 AC M4DXF1.1
#=GS A0A5N5F8J5_9ROSA/18-137 AC A0A5N5F8J5.1
#=GS R7V2S7_CAPTE/16-131 AC R7V2S7.1
#=GS A0A0E0EC33_9ORYZ/20-134 AC A0A0E0EC33.1
#=GS A0A0P1AC13_PLAHL/4-129 AC A0A0P1AC13.1
#=GS A0A665V8G7_ECHNA/6-123 AC A0A665V8G7.1
#=GS A0A8B9DFR8_ANSCY/6-122 AC A0A8B9DFR8.1
#=GS A0A540L6R7_MALBA/54-105 AC A0A540L6R7.1
#=GS A0A7K9QZT0_IRECY/6-122 AC A0A7K9QZT0.1
#=GS A0A7N1A0L8_KALFE/11-128 AC A0A7N1A0L8.1
#=GS A0A7K5XNM9_9CHAR/6-123 AC A0A7K5XNM9.1
#=GS A0A6J1ICA4_CUCMA/10-130 AC A0A6J1ICA4.1
#=GS A0A059LDF9_9CHLO/1-68 AC A0A059LDF9.1
#=GS A0A5F8H675_MONDO/29-94 AC A0A5F8H675.1
#=GS G1QJI6_NOMLE/6-114 AC G1QJI6.2
#=GS A0A7L0QKW5_SETKR/6-119 AC A0A7L0QKW5.1
#=GS A0A1Z5KRA5_FISSO/8-128 AC A0A1Z5KRA5.1
#=GS A0A0L0DLP1_THETB/9-126 AC A0A0L0DLP1.1
#=GS A0A7J8JK31_ROUAE/6-125 AC A0A7J8JK31.1
#=GS A0A7J9DWB5_9ROSI/22-142 AC A0A7J9DWB5.1
#=GS A0A2U9B3P0_SCOMX/48-164 AC A0A2U9B3P0.1
#=GS A0A2U3ZQ28_ODORO/6-125 AC A0A2U3ZQ28.1
#=GS A0A1U8BHP3_MESAU/3-94 AC A0A1U8BHP3.1
#=GS A0A4Y7IQ34_PAPSO/13-134 AC A0A4Y7IQ34.1
#=GS A0A1U8F2E6_CAPAN/18-139 AC A0A1U8F2E6.1
#=GS A0A7J7R362_PIPKU/6-124 AC A0A7J7R362.1
#=GS A0A7J7R365_PIPKU/3-93 AC A0A7J7R365.1
#=GS A0A7L0I1X8_AREIN/6-123 AC A0A7L0I1X8.1
#=GS A0A811S263_9POAL/38-153 AC A0A811S263.1
#=GS A0A6P5K088_PHACI/1-75 AC A0A6P5K088.1
#=GS A0A8C9CF05_PHOSS/6-125 AC A0A8C9CF05.1
#=GS A0A671WTM7_SPAAU/6-126 AC A0A671WTM7.1
#=GS A0A0A0K0I9_CUCSA/9-127 AC A0A0A0K0I9.1
#=GS A0A8K0MSU8_9ROSA/15-134 AC A0A8K0MSU8.1
#=GS A0A398ARM2_BRACM/7-124 AC A0A398ARM2.1
#=GS A0A7M7K4V1_VARDE/27-144 AC A0A7M7K4V1.1
#=GS A0A0B0MPC2_GOSAR/19-139 AC A0A0B0MPC2.1
#=GS A0A7K6HM30_9PASS/6-123 AC A0A7K6HM30.1
#=GS A0A1V4K4E7_PATFA/6-122 AC A0A1V4K4E7.1
#=GS A0A1V9XGV5_9ACAR/21-138 AC A0A1V9XGV5.1
#=GS A0A5E4GBG4_PRUDU/18-137 AC A0A5E4GBG4.1
#=GS A0A8B9DHQ4_ANSCY/6-122 AC A0A8B9DHQ4.1
#=GS R0G3I3_9BRAS/13-132 AC R0G3I3.1
#=GS J3MLC8_ORYBR/14-129 AC J3MLC8.1
#=GS A0A7K9MFW0_OCETE/6-122 AC A0A7K9MFW0.1
#=GS A0A7F8QZ13_LEPWE/5-97 AC A0A7F8QZ13.1
#=GS A0A8V0XLC3_CHICK/124-240 AC A0A8V0XLC3.1
#=GS A0A8B8YKT3_BALMU/6-125 AC A0A8B8YKT3.1
#=GS A0A1S3IFG1_LINUN/13-130 AC A0A1S3IFG1.1
#=GS H9GJL1_ANOCA/9-106 AC H9GJL1.2
#=GS A0A7J7R370_PIPKU/6-124 AC A0A7J7R370.1
#=GS A0A8B8YHQ8_BALMU/6-125 AC A0A8B8YHQ8.1
#=GS A0A8R1TS29_ONCVO/8-130 AC A0A8R1TS29.1
#=GS A0A836CG43_9STRA/7-127 AC A0A836CG43.1
#=GS A0A3L6RAB4_PANMI/14-130 AC A0A3L6RAB4.1
#=GS A0A6J2GTD1_9PASS/6-123 AC A0A6J2GTD1.1
#=GS A0A7L0KFF8_CHATO/6-122 AC A0A7L0KFF8.1
#=GS A0A5D2VTR0_GOSMU/22-142 AC A0A5D2VTR0.1
#=GS A0A8J5IKS3_9STRA/4-127 AC A0A8J5IKS3.1
#=GS D8QR20_SELML/8-120 AC D8QR20.1
#=GS A0A444ZFX5_ARAHY/14-132 AC A0A444ZFX5.1
#=GS A0A833SNH6_9HYME/7-81 AC A0A833SNH6.1
#=GS A0A8R1Y595_PRIPA/6-105 AC A0A8R1Y595.1
#=GS R1DH04_EMIHU/8-124 AC R1DH04.1
#=GS A0A2Z7B689_9LAMI/13-132 AC A0A2Z7B689.1
#=GS A0A6P7SJD8_OCTVU/7-123 AC A0A6P7SJD8.1
#=GS A0A164SJ25_DAUCS/16-130 AC A0A164SJ25.1
#=GS A0A3Q0DLF0_CARSF/6-125 AC A0A3Q0DLF0.1
#=GS A0A5F9DSV3_RABIT/9-102 AC A0A5F9DSV3.1
#=GS A0A6J3S459_TURTR/15-78 AC A0A6J3S459.1
#=GS A0A024TE63_9STRA/11-117 AC A0A024TE63.1
#=GS A0A8J6H0Q9_MICOH/6-50 AC A0A8J6H0Q9.1
#=GS A0A7S3ZK32_9STRA/30-141 AC A0A7S3ZK32.1
#=GS A0A7K7EGS7_9SYLV/6-122 AC A0A7K7EGS7.1
#=GS A0A7J7QUV4_MYOMY/6-124 AC A0A7J7QUV4.1
#=GS A0A8C1HBZ1_CYPCA/6-124 AC A0A8C1HBZ1.1
#=GS A0A2T7PK37_POMCA/12-127 AC A0A2T7PK37.1
#=GS G3VAL9_SARHA/35-130 AC G3VAL9.2
#=GS A0A8C4YZE9_GADMO/29-147 AC A0A8C4YZE9.1
#=GS A0A5N5NGM0_PANHP/36-153 AC A0A5N5NGM0.1
#=GS A0A811NJL1_9POAL/13-58 AC A0A811NJL1.1
#=GS W4G9K9_APHAT/12-124 AC W4G9K9.1
#=GS A0A851QCI6_ANHAN/6-122 AC A0A851QCI6.1
#=GS A0A835CV73_9HYME/7-113 AC A0A835CV73.1
#=GS A0A852NLY2_9PASS/6-122 AC A0A852NLY2.1
#=GS D3B279_POLPP/13-129 AC D3B279.1
#=GS A0A384APL2_BALAS/6-125 AC A0A384APL2.1
#=GS A0A7J6D5S8_9TELE/8-126 AC A0A7J6D5S8.1
#=GS A0A6P3RSY2_PTEVA/6-125 AC A0A6P3RSY2.1
#=GS A0A3P6U9U9_LITSI/15-135 AC A0A3P6U9U9.1
#=GS A0A8V5GBI5_MELUD/7-39 AC A0A8V5GBI5.1
#=GS A0A072VGB7_MEDTR/11-125 AC A0A072VGB7.1
#=GS A0A8C3ADM8_CYCLU/6-118 AC A0A8C3ADM8.1
#=GS A0A851MV89_9DEND/6-122 AC A0A851MV89.1
#=GS A0A8D2E7J9_THEGE/6-125 AC A0A8D2E7J9.1
#=GS A0A6J3A6V4_VICPA/6-125 AC A0A6J3A6V4.1
#=GS A0A670JG72_PODMU/11-129 AC A0A670JG72.1
#=GS A0A6I9LF56_PERMB/6-125 AC A0A6I9LF56.1
#=GS A0A7L3XX80_9AVES/6-123 AC A0A7L3XX80.1
#=GS A0A3Q7TE03_VULVU/6-125 AC A0A3Q7TE03.1
#=GS A0A3P8XQF0_ESOLU/5-99 AC A0A3P8XQF0.1
#=GS A0A8C5V2R5_MICMU/6-75 AC A0A8C5V2R5.1
#=GS Q0D620_ORYSJ/1-91 AC Q0D620.1
#=GS A0A251UJY2_HELAN/16-139 AC A0A251UJY2.1
#=GS A0A2Y9QAI7_DELLE/6-125 AC A0A2Y9QAI7.2
#=GS A0A6J3S4V7_TURTR/6-125 AC A0A6J3S4V7.1
#=GS A0A1E5UTD1_9POAL/13-129 AC A0A1E5UTD1.1
#=GS W5L9C7_ASTMX/6-122 AC W5L9C7.2
#=GS A0A1U7S2N8_ALLSI/1-74 AC A0A1U7S2N8.2
#=GS A0A6P5Z932_DURZI/17-137 AC A0A6P5Z932.1
#=GS C5KER9_PERM5/18-131 AC C5KER9.1
#=GS A0A804HUI9_MUSAM/16-136 AC A0A804HUI9.1
#=GS A0A7L1LLW9_HIMHI/6-123 AC A0A7L1LLW9.1
#=GS A0A7J7QUL0_MYOMY/6-124 AC A0A7J7QUL0.1
#=GS A0A2Y9KZV9_ENHLU/6-125 AC A0A2Y9KZV9.1
#=GS A0A6J0WIP2_ODOVR/6-125 AC A0A6J0WIP2.1
#=GS A0A8C8WRP0_PANLE/6-125 AC A0A8C8WRP0.1
#=GS A0A2G8JXY2_STIJA/12-130 AC A0A2G8JXY2.1
#=GS A0A7K8UQ20_OCEOC/6-124 AC A0A7K8UQ20.1
#=GS A0A1U8BGW7_MESAU/6-125 AC A0A1U8BGW7.1
#=GS A0A7J6WFK1_THATH/9-127 AC A0A7J6WFK1.1
#=GS A0A453L368_AEGTS/1-81 AC A0A453L368.1
#=GS A0A0E0I1F6_ORYNI/20-135 AC A0A0E0I1F6.1
#=GS A0A8C3ABX6_CYCLU/6-125 AC A0A8C3ABX6.1
#=GS D8R7W5_SELML/8-120 AC D8R7W5.1
#=GS F6H6W0_VITVI/17-133 AC F6H6W0.1
#=GS A0A2H9ZTV4_9ASPA/19-131 AC A0A2H9ZTV4.1
#=GS A0A0B2VQY1_TOXCA/8-125 AC A0A0B2VQY1.1
#=GS A0A8D0L4W0_SPHPU/6-111 AC A0A8D0L4W0.1
#=GS A0A8C5WCV7_9ANUR/6-124 AC A0A8C5WCV7.1
#=GS A0A0L9TBI1_PHAAN/14-132 AC A0A0L9TBI1.1
#=GS A0A7K9VLW2_ANSSE/6-122 AC A0A7K9VLW2.1
#=GS A0A553N9C7_TIGCA/62-175 AC A0A553N9C7.1
#=GS A0A059LHH4_9CHLO/4-75 AC A0A059LHH4.1
#=GS A0A8C3YQ93_9CETA/6-125 AC A0A8C3YQ93.1
#=GS E5RJN3_HUMAN/35-91 AC E5RJN3.1
#=GS A0A453L2S8_AEGTS/13-125 AC A0A453L2S8.1
#=GS A0A2P4X5P8_9STRA/1-59 AC A0A2P4X5P8.1
#=GS S4REW0_PETMA/6-124 AC S4REW0.1
#=GS A0A210Q4P8_MIZYE/15-131 AC A0A210Q4P8.1
#=GS A0A0D9QXR2_CHLSB/6-125 AC A0A0D9QXR2.1
#=GS A0A643CAD0_BALPH/33-89 AC A0A643CAD0.1
#=GS W2PAA8_PHYPN/43-161 AC W2PAA8.1
#=GS A0A2K5V816_MACFA/6-125 AC A0A2K5V816.2
#=GS A0A8B9N592_9AVES/24-70 AC A0A8B9N592.1
#=GS A0A8R2GAS6_BOMMO/47-175 AC A0A8R2GAS6.1
#=GS A0A2K6MS63_RHIBE/2-115 AC A0A2K6MS63.1
#=GS A0A8J4PU87_9MYCE/6-121 AC A0A8J4PU87.1
#=GS K7E0P5_MONDO/29-94 AC K7E0P5.2
#=GS A0A8R7THP3_TRIUA/19-135 AC A0A8R7THP3.1
#=GS A0A251IX81_MANES/10-69 AC A0A251IX81.1
#=GS CNDH2_XENTR/6-124 AC Q28GV1.1
#=GS A0A175YGY2_DAUCS/12-136 AC A0A175YGY2.1
#=GS B6AAF0_CRYMR/11-138 AC B6AAF0.1
#=GS A0A4W4EH37_ELEEL/6-132 AC A0A4W4EH37.1
#=GS A0A6P6K038_CARAU/8-126 AC A0A6P6K038.1
#=GS A0A4U5LWF8_STECR/78-160 AC A0A4U5LWF8.1
#=GS A0A8C4S6H8_ERPCA/7-125 AC A0A8C4S6H8.1
#=GS A0A8D0C4W3_SALMN/6-124 AC A0A8D0C4W3.1
#=GS A0A7K8SBN8_9PASS/6-47 AC A0A7K8SBN8.1
#=GS A0A2K1R9A7_POPTR/10-127 AC A0A2K1R9A7.1
#=GS A0A8W8NGT5_CRAGI/33-151 AC A0A8W8NGT5.1
#=GS A0A1S2XDX9_CICAR/11-131 AC A0A1S2XDX9.1
#=GS A0A8J5CP53_CHIOP/18-136 AC A0A8J5CP53.1
#=GS A0A8R1DJV6_CAEJA/12-129 AC A0A8R1DJV6.1
#=GS A0A6P8SB78_GEOSA/6-124 AC A0A6P8SB78.1
#=GS A0A1I7RK57_BURXY/9-128 AC A0A1I7RK57.1
#=GS A0A850TD68_GRUAM/6-125 AC A0A850TD68.1
#=GS A0A8C5L6W0_JACJA/6-125 AC A0A8C5L6W0.1
#=GS H3GF21_PHYRM/341-464 AC H3GF21.1
#=GS A0A6A2YWF7_HIBSY/19-137 AC A0A6A2YWF7.1
#=GS G3TYE6_LOXAF/6-125 AC G3TYE6.1
#=GS A0A803LS76_CHEQI/16-103 AC A0A803LS76.1
#=GS A0A2K6MS74_RHIBE/12-103 AC A0A2K6MS74.1
#=GS F6ZEU6_CIOIN/7-122 AC F6ZEU6.2
#=GS A0A103XQP7_CYNCS/16-136 AC A0A103XQP7.1
#=GS A0A8C4C468_9TELE/6-124 AC A0A8C4C468.1
#=GS A0A8D2PT08_ZOSLA/6-73 AC A0A8D2PT08.1
#=GS A0A540LZE5_MALBA/18-137 AC A0A540LZE5.1
#=GS A0A7L1FWG2_SYLBO/6-122 AC A0A7L1FWG2.1
#=GS A0A662X5Z3_9STRA/56-135 AC A0A662X5Z3.1
#=GS A0A7J7R3H0_PIPKU/1-74 AC A0A7J7R3H0.1
#=GS A0A7J9J088_9ROSI/22-142 AC A0A7J9J088.1
#=GS A0A5N4DH99_CAMDR/35-153 AC A0A5N4DH99.1
#=GS A0A7K6C5Y0_PTIVI/6-122 AC A0A7K6C5Y0.1
#=GS A0A835MXK9_9ROSI/9-127 AC A0A835MXK9.1
#=GS A0A6P4D125_ARADU/14-132 AC A0A6P4D125.1
#=GS A0A833WP17_PHYIN/4-127 AC A0A833WP17.1
#=GS A0A6P6LZY0_CARAU/6-124 AC A0A6P6LZY0.1
#=GS G0MG60_CAEBE/16-149 AC G0MG60.1
#=GS A0A8U0SIF2_MUSPF/6-125 AC A0A8U0SIF2.1
#=GS A0A0N4WHL8_HAEPC/10-128 AC A0A0N4WHL8.1
#=GS K0RT80_THAOC/11-137 AC K0RT80.1
#=GS CNDH2_MOUSE/6-125 AC Q8BSP2.1
#=GS A9V3Q2_MONBE/12-130 AC A9V3Q2.1
#=GS A0A7L2IJE6_9PICI/6-123 AC A0A7L2IJE6.1
#=GS A0A7L2ZML5_9PASE/6-122 AC A0A7L2ZML5.1
#=GS A0A8C4V959_FALTI/6-123 AC A0A8C4V959.1
#=GS D6WCL1_TRICA/4-108 AC D6WCL1.1
#=GS A0A368H3V7_ANCCA/10-120 AC A0A368H3V7.1
#=GS A0A8D2JE68_SCIVU/6-125 AC A0A8D2JE68.1
#=GS A0A7K5FIU8_PROAR/4-122 AC A0A7K5FIU8.1
#=GS A0A8I3Q2D0_CANLF/6-133 AC A0A8I3Q2D0.1
#=GS A0A6G0HPN0_LARCR/6-124 AC A0A6G0HPN0.1
#=GS A0A8C9PKL5_SPEDA/59-151 AC A0A8C9PKL5.1
#=GS A0A498ICR5_MALDO/54-106 AC A0A498ICR5.1
#=GS A0A3Q1ICB3_ANATE/6-128 AC A0A3Q1ICB3.1
#=GS A0A0D3AD26_BRAOL/8-125 AC A0A0D3AD26.1
#=GS A0A7K4WXS0_9TYRA/6-93 AC A0A7K4WXS0.1
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A0A1S3Z2T0_TOBAC/10-128 ................................srg---FHNLQPHR..DLE.S..N....WG...VD..VAK....NLED..YLLK.....I.....C.S.G....EIAAa.......dhDN....................aNC...LSV....N.FAEAALLLQGSVQVYSRKVEYLYSLVL.......H.A....LE.FI....TQKSE....QDH..PE..S...AS.A...Q..A..E...EN--.........ANDEEND..PFWVSEEI-p...............................................
A0A444TZI6_ACIRT/59-143 ..................................a-RYTHLLQPIR..DMT.K..N....WE...VD..VAA....QLGE..YMHE.....L.....D.Q.I....CISF..........DG.....................GK...TTM....N.FAEAALLIQGSACIYSKKF--------.......-.-....--.--....-----....---..--..-...--.-...-..-..-...----.........-------..---------lslddingtnksnmdmrkn.............................
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A0A7N2LVV4_QUELO/11-127 ................................sgy----HTVQPER..DLQ.S..N....WE...VD..LAK....KLED..YLFK.....I.....C.S.G....EIPY..........DD.....................-H...APV....N.FAEAALLLQGSVQVYSRKVEYLYSLVL.......R.A....LE.FL....SQKRQq..dQSE..GT..S...VQ.P...E..E..S...GSHA.........VADEEND..LFWGSDDIP................................................
A0A2Y9RAB7_TRIMA/6-125 ..................................a-RFAHLLQPIR..DLT.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DE.....................GK...TTM....N.FIEAALLIQGSACVYSKKVEYLYSLVY.......Q.A....LD.FI....SGKKQ....AKQ..LS..L...AR.D...D..G..G...AGDAs......sgGPREPED..EFLSLDEM-p...............................................
A0A1V9Y6W1_9STRA/4-113 ................................aat---GHLLEPIR..DLG.-..-....WQ...LD..LAA....ELEE..YLQA.....I.....Q.-.-....---A..........DE.....................-S...QLV....N.FAQAALLVQNSTVRYSKKVENLYSLVL.......E.A....LS.QF....QSSKA....NQH..AS..K...RQ.K...T..P..H...GSNA.........RRGS---..---------fddtlalamsdih...................................
A0A6V7VPS0_9BILA/165-284 ...................................ERYKFLLQPVK..DLA.T..N....WD...VD..IAK....TLED..YIQK.....V.....V.E.D....SNAVlv......gsDG.....................RR...KVF....N.FAEAALLIHGTTNVYVKKIEYVLQIAL.......N.F....FD.EL....KEDKP....QGK..NK..K...KN.A...N.dD..Q...EGEL.........ADDDNQ-..---------evrhekqk........................................
A0A0K0DMZ3_ANGCA/10-124 ..................................h-RWAFLLRPAT..NLD.K..N....FK...TN..ISK....ELDD..YCLS.....L.....G.E.I....TADEk.......feTN.....................NQ...ARF....N.FDEAAMLIERSAIVFGRKVDNLHSQAM.......H.F....ME.TL....QPQKT....KKT..KK..I...AG.K...E..D..-...DEGF.........V------..---------eeneavidpcd.....................................
A0A3Q7N0L4_CALUR/6-125 ..................................a-RFAHLLQPIR..DLT.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DE.....................GK...TTM....N.FIEAALLIQGSACVYSKKVEYLYSLVY.......Q.A....LD.FI....SGKKR....AKQ..LS..P...VR.E...N..G..A...NGDTs......stAPQEAED..QFLSLDDL-p...............................................
A0A7L1QVG0_9PASS/1-53 ..................................q-----------..---.-..-....--...--..---....----..----.....-.....-.-.-....----..........--.....................--...---....-.------------------VEYLYMLVC.......Q.T....LD.CI....SNKKK....EKL..PP..S...VG.P...E..G..R...DADA.........TFTDPEE..EFLSLDDL-p...............................................
A0A6I9LF62_PERMB/1-75 ...................................-----------..---.-..-....--...--..---....----..----.....-.....-.-.-....----..........--.....................--...--M....N.FIEAALLIQGSACVYSKKVEYLYSLVY.......Q.A....LD.FI....SGKRR....AKQ..LS..L...VQ.E...D..G..S...NRAVn......sgAPYETED..ELLSLDDF-p...............................................
A0A8J5YZF1_9ROSI/22-142 .................................gk--F-HGVQPER..DLE.A..N....WE...VD..LAK....KLED..YLLK.....I.....C.S.G....EITGs.......qdDE.....................GH...SSV....N.FAEAALLLQGSVQVYSRKVEYLYNLVL.......H.A....LE.FL....SQKRQq..dQPN..GE..S...VQ.A...E..E..S...ASRA.........SPDEDHD..KFWDLDDIP................................................
A0A7K9A3I8_9PASS/6-123 ...................................SRFLHLLQPIR..DLT.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DN.....................GK...TTM....N.FMEAALLIQGSACIYSRKVEYLYMLVC.......Q.T....LD.CI....SNKKR....EKL..PT..S...LG.T...D..G..Q...DADA........tFTDKEKQ..LFLSLDDI-r...............................................
A0A6P5K020_PHACI/6-125 ..................................t-RFAHLLQPIR..DLT.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DE.....................GK...TTM....N.FIEAALLIQGSACVYSKKVEYLYSLVY.......Q.A....LD.FI....SGKKR....SKQ..AT..S...VQ.P...D..G..Q...NTDDs......ggARPEPEE..EFLSLDDL-p...............................................
A0A6A3CP52_HIBSY/19-139 ................................gkf----YVAQPGL..DLE.A..N....WE...VD..LAK....KLED..YLLK.....I.....C.S.G....EITGs.......qdDD.....................GH...SSV....N.FAEAALLLQGSVQVYSRKVEYLYNLVL.......H.A....LE.FL....SQKRQq..dKPN..GA..S...DQ.A...E..Q..I...ASHA.........TSDEDHD..KFWDLDDIP................................................
A0A3P8UAK5_AMPPE/6-102 ...................................SRYVHLLQPIR..ELT.K..N....WD...ID..LAS....ELND..YLDE.....L.....D.E.M....CITF..........DG.....................GK...TRL....N.FAEAALLIQGSASIYSKKVELLHNLVF.......Q.T....LE.FI....S----....---..--..-...--.-...-..-..-...----.........-------..---------vhlvsvsdlifcrqte................................
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A0A078GP53_BRANA/8-125 .................................er--I-HRVQPER..DLV.A..N....WE...VD..LSE....KLEE..YLLK.....I.....C.S.G....EITG..........TE.....................ED...SPV....N.FAEAALLLQGSVQVYSKKVEYLYNLVL.......R.T....LE.FL....SNQREq..eESK..GT..S...HE.A...E..A..S...SSRQ.........ADEEEND..LFWNVDDIP................................................
L5LE81_MYODS/350-460 ..............................xxxxx-----------..--T.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DE.....................GK...TTM....N.FVEAALLIQGSACVYSKKVEYLYSLVY.......Q.A....LD.FI....SGKRR....ARQ..LA..A...QE.D...-..G..A...SRDAs......srASQRVED..EFLSLDDL-p...............................................
A0A0M0JS52_9EUKA/11-131 ...................................SRYAHLLEPIR..ELE.R..N....WS...ID..IAS....ELED..YLAE.....L.....E.A.I....TIAF..........ED.....................-G...KRL....D.FAEAALVIQGSTCIYGKKVDSLYELVL.......N.T....LD.QV....IHKKK....EKE..QQ..Q...RQ.R...Q..Q..Q...EQQDde....piePEDGEEE..PFVTLDDT-l...............................................
A0A383WND1_TETOB/13-107 ..................................n-RFSYLLQPIR..DLA.A..N....WD...IN..IAG....ELEE..YLEE.....L.....E.H.L....TFTI..........EG.....................--...---....-.-------SQGTTCVFSKKVEYLHSLVY.......Q.A....LE.TI....FNKKQ....KER..QA..A...AN.K...N..K..-...----.........-------..---------aarggdaslgad....................................
A0A485NPA6_LYNPA/6-125 ..................................a-RFAHLLQPIR..DLT.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DE.....................GK...TTM....N.FIEAALLIQGSACVYSKKVEYLYSLVY.......Q.A....LD.FI....SGKKR....AKQ..LS..S...VR.E...Q..G..A...DGDAs......aeAPQEADD..QFLSLDDL-p...............................................
A0A7L1NI84_RHICY/6-120 ..................................l-RFQHLLQPIR..DLT.K..N....WE...VD..VAA....QLEE..YLDE.....L.....E.Q.I....CISF..........DN.....................GR...TTM....N.FTEAAMVIQGSACIYSRKVEYLYSLVY.......Q.A....LD.LI....SNKKR....QKL..PS..S...LG.P...D..G..K...DAD-.........-ANFEEE..EFLSLDDL-p...............................................
A0A8J6B2B0_ELECQ/6-38 ...................................SRYTHLLQPIR..DMT.K..N....WE...LD..VAA....QLGE..YLEE.....V.....-.-.-....----..........--.....................--...---....-.---------------------------.......-.-....--.--....-----....---..--..-...--.-...-..-..-...----.........-------..---------h...............................................
A0A6I9XVN6_9SAUR/29-101 ....................wtlmdeaasiwreic-----------..---.-..-....--...--..---....----..----.....-.....-.-.-....----..........--.....................--...---....-.----------------NEVEYLYTLVY.......Q.A....LD.FI....SSKKR....EKQ..PT..S...VG.A...D..G..T...DGDVsa.....gpGAAAEEE..EFLSLDDI-q...............................................
A0A8J2QGB0_9NEOP/8-126 ................................eiv---AELMKPIS..DVR.R..S....FD...TD..LSA....LLEE..YLTE.....A.....G.Q.Q....ALEAea......sgNH.....................SY...STP....N.FAEVALLLQQSANIYGRKVDCLYSHVL.......C.V....SD.AL....HNNTL....EAS..VS..A...DE.-...-..-..-...----.........-------..---------phtpsggrrkrkasvngdfdyi..........................
M4C4N9_HYAAE/4-134 ..................................g-RLQHLLQPLR..DLS.K..N....WN...ID..LAT....ELED..YMDK.....L.....E.T.L....SIAFd.......peNGsaqis..........rdgeggAT...GVM....N.FAEAALLIQGTSLIYSRKVEYLHALVY.......Q.T....LA.HL....SQQQD....DNQ..QS..Q...ER.G...K..R..G...TGET.........QEDEDGX..XASVL----dtal............................................
A0A016RUU2_9BILA/10-120 ...................................QRYAFLLRPVK..DLG.K..N....FE...IN..IAK....ELDD..YCQQ.....L.....K.S.A....AENEe.......ydVD.....................NQ...HRF....N.FAEAAMLIQGSAFVFGRKVDYVHSQAV.......H.F....FE.AL....QPQKS....KKK..KK..A...GG.G...-..-..-...----.........-------..---------dddegfvddngdpl..................................
A0A6J0NRQ5_RAPSA/7-127 .................................er--I-HTVQPER..DLV.A..N....WE...VD..LSE....KLEE..YLLK.....I.....C.T.G....EITGn.......edED.....................GQ...IPV....N.FAEAALLLQGSVQVYSKKVEYLYNLVL.......R.T....LE.FL....SKQREq..eESK..ST..S...NE.A...E..A..S...SSRQ.........VDEEEND..LFWNVDDIP................................................
A0A0E0Q901_ORYRU/20-135 ................................arf----PILQANR..DPE.S..N....WE...VD..VAK....SLEE..YLLR.....I.....C.S.G....EISG..........ED.....................GA...HSV....N.FAEAALLLQGSVQVYSRKVEYLYTLVL.......N.A....LE.FL....SQKKQ....DQE..NS..S...AQ.A...N..E..S...DRST.........VPNEEDD..VFSGLDDVP................................................
A0A3L6R900_PANMI/15-131 ................................grf----PILQANR..DPE.L..N....WK...VD..VAK....RLKE..YLLK.....I.....C.S.G....EVTG..........ED.....................GA...HSV....N.FTEAVLLLQGLVQVYSTKVQNLYSLVL.......H.A....LE.FL....SQKKQ...dQHE..NG..S...AH.G...N..E..N...DTSM.........ISNEEDD..VFMGLDDVP................................................
A0A6P6WXK3_COFAR/13-133 ................................gif----HSVQPLR..DLE.S..N....WA...VD..LAK....NLSE..YLLK.....I.....C.S.G....EITS..........DDh..................dvPQ...LSV....N.FAEAALLLQGSVQVYSRKVEYLYSLVL.......H.A....LE.FI....SQKSS....QEQ..GT..S...AS.A...Q..S..E...ESGLe.......aPHEEEDD..RFWGLDDIP................................................
A0A7L0DPV4_9CHAR/6-123 ...................................SRFLHLLQPIR..DLT.K..N....WE...VD..VAS....QLGE..YLEE.....L.....D.Q.I....SISF..........DN.....................GK...TTM....N.FIEAALVIQGSACVYSRKVEYLYSLVY.......Q.T....LD.FI....SNKKR....EKL..PS..S...LG.Q...D..G..R...DNDA........tFGAQEQE..EFLSLDDI-r...............................................
A0A3Q7PF26_CALUR/6-125 ..................................a-RFAHLLQPIR..DLT.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DE.....................GK...TTM....N.FIEAALLIQGSACVYSKKVEYLYSLVY.......Q.A....LD.FI....SGKKR....AKQ..LS..P...VR.E...N..G..A...NGDTs......stAPQEAED..QFLSLDDL-p...............................................
A0A7L4I2X7_SCOUM/6-122 ...................................SRFLHLLQPIR..DLT.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DN.....................GK...TTM....N.FIEAALLIQGSACIYSRKVEYLYSLVY.......Q.T....LD.FI....SNKKR....EKQ..PS..S...VG.Q...D..N..E...DADA.........SFGDEEE..EFLSLDDI-s...............................................
A0A225X0F2_9STRA/4-124 ...................................SRLQHLLQPIR..DLS.K..N....WN...ID..LAS....ELEE..YMDK.....L.....E.H.L....SIAF..........DTedga............riardGD...NVM....N.FAEAALLIQGTSVIYSRKVEYLHALVY.......Q.T....LA.HL....SKQQD....DAQ..QT..Q...QS.E...T..G..E...-PRE.........ED-----..---------egdssvfsnp......................................
A0A7E4ZX40_PANRE/12-107 ..................................e-KFAYLFKPIT..DFA.K..G....FE...ID..LIE....VLRD..YD--.....-.....-.S.K....TFEA..........D-.....................--...TGF....N.FVNAAAMLQGTTNVYGKRVDILHKAVS.......N.F....TD.PA....LEKER....RKQ..AA..A...--.-...-..-..-...----.........-------..---------xxxxxxxxxxxx....................................
A0A6A4C216_9STRA/4-125 ..................................g-RLQHLLQPIR..DLS.K..N....WN...ID..LAS....ELEE..YMDK.....L.....E.H.L....SIAFd.......peDGasia.............rdgdGP...GVM....N.FAEAALLIQGTSVIYSRKVEYLHALVY.......Q.T....LG.HL....SKQQD....DRQ..SQ..R...QQ.S...A..D..K...GETV.........EEDDD--..---------dgdag...........................................
A0A2U9B363_SCOMX/6-122 ...................................SRFAHLLQPIR..ELT.K..N....WD...ID..VAS....ELND..YLEE.....L.....D.D.M....CITF..........DG.....................GK...TRL....N.FAEAALLIQGSACIYSKKVELLHSLVY.......Q.T....LE.NI....NDKNK....KRN..KQ..T...SE.S...P..H..-...DDDT.........ERDEDED..VFTPLD---idvs............................................
A0A3Q1M6H8_BOVIN/6-125 ..................................a-RFAHLLLPIR..DLT.R..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DK.....................GK...TTM....N.FIEAALLIQGSACVYSKKVEYLYSLVY.......Q.A....LD.FI....SGKKQ....AKQ..LS..S...TP.E...D..G..T...IGDAs......srAPQEAEQ..KFRALDDL-s...............................................
A0A8C3VBK2_CATUS/6-46 ...................................SRFLHLHQPIR..DLT.K..N....WE...VD..VAS....QLGE..YLEE.....V.....T.G.-....----..........--.....................--...---....-.---------------------------.......-.-....--.--....-----....---..--..-...--.-...-..-..-...----.........-------..---------tplspfp.........................................
A0A453BE08_AEGTS/13-129 ................................grf----PILQANR..DPE.S..N....WE...VD..VAK....SLEE..YLLK.....I.....C.S.G....EISA..........ED.....................GA...HSF....N.FAEAALLLQGSVQVYSRKVEYLYSLVL.......H.A....LE.FL....SQNKQ...dQQE..KG..S...TE.A...N..E..N...GPST.........TANKEDD..MFMGLDDVP................................................
A0A8B8YQM4_BALMU/6-125 ..................................a-RFAHLLQPIR..DLT.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DE.....................GK...TTM....N.FAEAALLVQGSACVYSKKVEYLYSLVY.......Q.A....LD.FI....SGKKR....AKQ..LS..C...ER.E...D..G..P...IGDAg......srAPQEVEY..EFLSLDDL-s...............................................
A0A662X5Z3_9STRA/4-54 ..................................g-RFQHLLQPIR..DLS.K..N....WN...ID..LAT....ELEE..YMDK.....L.....D.S.L....NIAF..........DP.....................S-...---....-.---------------------------.......-.-....--.--....-----....---..--..-...--.-...-..-..-...----.........-------..---------daasgasfg.......................................
A0A8B7TEG2_HIPAR/7-64 .................................gt-----------..---.-..-....--...--..---....----..----.....-.....-.-.-....----..........--.....................--...---....-.------------------VEYLYSLVY.......Q.A....LD.FI....SGKRR....AKQ..LS..S...VQ.E...N..G..A...SGDTgs.....gaRQEVADD..EFLSLDDL-p...............................................
A0A811LJK7_9BILA/183-302 ..................................a-RYRYLLQPIR..DLS.E..H....LD...DD..IYE....ILGV..YLEK.....L.....R.S.D....RERNvq......geDG.....................EL...IKF....N.FSEAAVLLQSSFQLFAKKVDRLYDLVC.......E.A....YS.GT....VTKKK....GKK..SG..I...G-.D...S..S..D...ETDI.........TRRKNDF..DF-------kvdidsl.........................................
A0A1U8JLP7_GOSHI/22-142 .................................gk--F-HGLQPER..DLE.A..N....WE...VD..LAK....KLED..YLLK.....I.....C.S.G....EITGs.......qdDD.....................GH...SPV....N.FAEAALLLQGSVQVYSRKVEYLYNLVL.......H.A....LE.FL....SQKRQq..dQPN..GE..S...VQ.A...E..E..S...ASRA.........SPDEDHD..KFWDLDDIP................................................
A0A2A2LM58_9BILA/14-138 ..................................s-RWAYLLQPIK..DLQ.D..A....FK...ID..LQT....ILEE..YDKA.....L.....E.E.V....DVSQaqgg.adtrqQD.....................RS...GTV....D.FAEAALFVRGVTGIYTTKTVALHTDST.......Q.L....MG.YL....MGKGR....ADT..TT..L...TA.L...S..R..-...----.........-------..---------srrkpaqnremrvlmeddwt............................
E5RJL4_HUMAN/6-34 ..................................a-RFAHLLQPIR..DLT.K..N....WE...VD..VAA....QL--..----.....-.....-.-.-....----..........--.....................--...---....-.---------------------------.......-.-....--.--....-----....---..--..-...--.-...-..-..-...----.........-------..---------agsd............................................
A0A3L6SZT3_PANMI/14-130 ................................grf----PILQANR..DPE.S..N....WE...VD..VAK....RLEE..YLLK.....I.....C.S.G....EVTG..........ED.....................GA...HSV....N.FAEAALLLQGSIQVYSRKVEYLYSLVL.......H.A....LE.FL....SQKKQ...dQHE..NG..S...AH.G...N..E..N...DASS.........ISNEEDD..VFMGLDDVP................................................
A0A7L0C792_9AVES/6-122 ...................................SRFLHLLQPIR..DLT.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DN.....................GK...TTM....N.FVEAALLIQGSACVYSRKVEYLYLLVY.......Q.M....LD.FI....SNKKR....EKQ..PS..S...VQ.Q...D..G..K...DTDA.........SFGADEE..EFLSLDDI-g...............................................
S4REW3_PETMA/1-74 ...................................-----------..---.-..-....--...--..---....----..----.....-.....-.-.-....----..........--.....................--...--M....N.FAEAALLIQGSACIYSKKVEYLYSLVY.......Q.T....LD.MI....SDKKR....SQK..VT..D...VG.Q...E..G..V...DSDTs.......fAYKHNEE..EFLSLDDI-q...............................................
G5B2G5_HETGA/6-125 ..................................a-RFAHLLQPIR..DLT.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DE.....................GK...TTM....N.FIEAALLIQGSACVYSKKVEYLYSLVY.......Q.A....LD.FI....SGKRR....AKQ..LS..S...GQ.E...D..G..A...GGASn......skALHEAED..EFLSLDNF-p...............................................
A0A6P7SK87_OCTVU/7-123 ..................................g-RFNFMLQPIR..DLT.K..N....WD...VD..IAS....HLED..YLEE.....L.....E.N.V....AITF..........DG.....................-G...RTM....N.FAEAALLIQGSTCVYSRKVEYLYALVY.......E.V....LD.LL....VNKRR...nKQS..ND..K...GD.N...A..A..D...DPDV.........TFGGDDL..ELLPLDDI-e...............................................
A0A6J2ACB1_ACIJB/6-125 ..................................a-RFAHLLQPIR..DLT.K..N....WE...VD..VAA....QLGE..YLEE.....L.....D.Q.I....CISF..........DE.....................GK...TTM....N.FIEAALLIQGSACVYSKKVEYLYSLVY.......Q.A....LD.FI....SGKKR....AKQ..LS..S...VR.E...Q..G..A...DGDAs......seAPQEADD..QFLSLDDL-p...............................................
A0A4D8XPC4_9ALVE/12-104 ..................................t-KYGHLTRPLK..EAV.A..C....WD...ID..LKE....VMES..FIAA.....Q.....D.D.D....VGSM..........DP.....................-S...RML....N.FAQAGMLVSSTATNYSRKVEHLYTLVY.......S.T....LD.TM....ISESF....---..--..-...--.-...-..-..-...----.........-------..---------qgnrrngtg.......................................
A0A6J1SJI8_FRAOC/3-116 ..............................vlnth------LPKIL..DLA.K..N....FN...LD..LSG....VLAG..YAQK.....L.....H.D.D....VPEL..........--.....................-M...ENF....S.FPEAALLLQHCAEIYGRKVDYVHTLAL.......E.L....CE.NM....NSRMY....APE..SA..Q...GQ.-...-..-..-...----.........-------..---------gaaepasispkklanarkkktvsii.......................
A0A067FWP7_CITSI/19-139 ................................sdv---RFTVQPER..ELQ.A..N....WE...VD..LAK....KLED..YLLK.....I.....C.S.G....QVTA..........SEs...................lDS...ISV....N.FAEAALLVQGSVQVYSRKVEYLYNLVL.......H.T....LE.FI....SQKSQq..dQIE..GT..P...VQ.A...E..E..S...GSHA.........VAGEEND..FFWGFDDVP................................................
#=GC seq_cons ..................................h.Ra.HLLQPlR..DLs.c..N....WE...VD..lAt....pLtE..YLpc.....L.....c.p.h....sIoh..........Dp.....................Gc...ssh....N.FhEAALLIQGSssVYS+KVEYLYoLVh.......p.s....L-.al....SsK+p....ppp...s..u...sp.t...p..t..t...ssss.........s.pctpp...FhsLDDh.................................................
//
