#=GF ID CNPase
#=GF AC PF05881.16
#=GF DE 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
#=GF AU Moxon SJ;0000-0003-4644-1816
#=GF AU Mazumder R;0000-0001-8823-9945
#=GF SE Pfam-B_9997 (release 8.0)
#=GF GA 25.00 25.00;
#=GF TC 25.10 26.40;
#=GF NC 23.90 24.50;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF CL CL0247
#=GF RN [1]
#=GF RM 11885989
#=GF RT Assignment of the 1H, 13C and 15N resonances of the catalytic
#=GF RT domain of the rat 2',3'-cyclic nucleotide 3'-phosphodiesterase.
#=GF RA Kozlov G, Lee J, Gravel M, Ekiel I, Braun PE, Gehring K;
#=GF RL J Biomol NMR 2002;22:99-100.
#=GF RN [2]
#=GF RM 12466548
#=GF RT Detection of novel members, structure-function analysis and
#=GF RT evolutionary classification of the 2H phosphoesterase
#=GF RT superfamily.
#=GF RA Mazumder R, Iyer LM, Vasudevan S, Aravind L;
#=GF RL Nucleic Acids Res 2002;30:5229-5243.
#=GF DR INTERPRO; IPR047325;
#=GF DR SCOP; 1n4t; fa;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family consists of the eukaryotic protein 2',3'-cyclic
#=GF CC nucleotide 3'-phosphodiesterase (CNP). 2',3'-cyclic nucleotide
#=GF CC 3'-phosphodiesterase (CNP) is one of the earliest myelin-related
#=GF CC proteins expressed in differentiating oligodendrocytes and
#=GF CC Schwann cells. CNP is abundant in the central nervous system and
#=GF CC in oligodendrocytes. This protein is also found in mammalian
#=GF CC photoreceptor cells, testis and lymphocytes. Although the
#=GF CC biological function of CNP is unknown, it is thought to play a
#=GF CC significant role in the formation of the myelin sheath, where it
#=GF CC comprises 4% of total protein. CNP selectively cleaves
#=GF CC 2',3'-cyclic nucleotides to produce 2'-nucleotides in vitro.
#=GF CC Although physiologically relevant substrates with 2',3'-cyclic
#=GF CC termini are still unknown, numerous cyclic phosphate containing
#=GF CC RNAs occur transiently within eukaryotic cells. Other known
#=GF CC protein families capable of hydrolysing 2',3'-cyclic nucleotides
#=GF CC include tRNA ligases and plant cyclic phosphodiesterases. The
#=GF CC catalytic domains from all these proteins contain two
#=GF CC tetra-peptide motifs H-X-T/S-X, where X is usually a hydrophobic
#=GF CC residue. Mutation of either histidine in CNP abolishes enzymatic
#=GF CC activity [1]. CNPases belong to the 2H phosphoesterase
#=GF CC superfamily. They share a common active site, characterised by
#=GF CC two conserved histidines, with the bacterial tRNA-ligating
#=GF CC enzyme LigT, vertebrate myelin-associated 2',3'
#=GF CC phosphodiesterases, plant Arabidopsis thaliana CPDases and
#=GF CC several several bacteria and virus proteins [2].
#=GF SQ 874
#=GS A0A091E0B8_FUKDA/749-983 AC A0A091E0B8.1
#=GS A0A3P7LKK7_DIBLA/18-102 AC A0A3P7LKK7.1
#=GS A0A8J5D0M3_CHIOP/233-379 AC A0A8J5D0M3.1
#=GS A0A7K7TNE7_9CHAR/184-420 AC A0A7K7TNE7.1
#=GS A0A673Z9X0_SALTR/444-679 AC A0A673Z9X0.1
#=GS A0A6I8P2W7_ORNAN/186-420 AC A0A6I8P2W7.1
#=GS A0A6I9I151_VICPA/185-419 AC A0A6I9I151.1
#=GS A0A7L4F010_HIRRU/184-419 AC A0A7L4F010.1
#=GS A0A8C8ZMS4_PROSS/186-420 AC A0A8C8ZMS4.1
#=GS A0A6P3RFK6_PTEVA/164-398 AC A0A6P3RFK6.1
#=GS A0A7K7VIY3_EUDEL/184-420 AC A0A7K7VIY3.1
#=GS A0A8J6ERG2_ELECQ/167-402 AC A0A8J6ERG2.1
#=GS A0A7M7P844_STRPU/199-446 AC A0A7M7P844.1
#=GS A0A2P4TCH0_BAMTH/185-419 AC A0A2P4TCH0.1
#=GS A0A8C3R4P8_9PASS/185-378 AC A0A8C3R4P8.1
#=GS A0A553N7V9_TIGCA/9-107 AC A0A553N7V9.1
#=GS A0A8C7KMD5_ONCKI/446-680 AC A0A8C7KMD5.1
#=GS A0A6I9IYG3_CHRAS/165-399 AC A0A6I9IYG3.1
#=GS G3HLV7_CRIGR/722-956 AC G3HLV7.1
#=GS A0A7K9R9N8_IRECY/184-420 AC A0A7K9R9N8.1
#=GS A0A452CDT9_BALAS/183-417 AC A0A452CDT9.1
#=GS R7TBC5_CAPTE/166-377 AC R7TBC5.1
#=GS A0A093G8V6_DRYPU/185-419 AC A0A093G8V6.1
#=GS A0A4W5R5A7_9TELE/450-685 AC A0A4W5R5A7.1
#=GS A0A8B7TBV2_HIPAR/164-398 AC A0A8B7TBV2.1
#=GS A0A0A0A2A1_CHAVO/185-418 AC A0A0A0A2A1.1
#=GS A0A7K9FHP9_STEPR/184-420 AC A0A7K9FHP9.1
#=GS A0A1A6GIX1_NEOLE/184-418 AC A0A1A6GIX1.1
#=GS A0A7K5WN09_9SYLV/184-419 AC A0A7K5WN09.1
#=GS A0A4W5NBF2_9TELE/453-689 AC A0A4W5NBF2.1
#=GS A0A7L0FNB0_CORCN/184-420 AC A0A7L0FNB0.1
#=GS A0A813TI79_ADIRI/185-343 AC A0A813TI79.1
#=GS A0A7L2MSC6_9PASS/184-419 AC A0A7L2MSC6.1
#=GS A0A8C6QJ81_NANGA/185-419 AC A0A8C6QJ81.1
#=GS A0A4Z2BXW5_9TELE/366-450 AC A0A4Z2BXW5.1
#=GS A0A6J3QMK4_TURTR/165-399 AC A0A6J3QMK4.1
#=GS A0A6P3HPW2_BISBI/246-443 AC A0A6P3HPW2.1
#=GS A0A5A9N9E3_9TELE/189-425 AC A0A5A9N9E3.1
#=GS A0A850U4E0_GRUAM/184-420 AC A0A850U4E0.1
#=GS A0A7L2UPQ1_BALRX/184-420 AC A0A7L2UPQ1.1
#=GS A0A7L1WWJ2_9PASS/184-420 AC A0A7L1WWJ2.1
#=GS A0A7J8G649_ROUAE/184-276 AC A0A7J8G649.1
#=GS A0A3Q7NBP9_CALUR/165-399 AC A0A3Q7NBP9.1
#=GS G1RK75_NOMLE/186-420 AC G1RK75.1
#=GS A0A452GH49_9SAUR/227-462 AC A0A452GH49.1
#=GS A0A7L3KTM5_9PASS/184-420 AC A0A7L3KTM5.1
#=GS A0A7L3VKX5_MOLAT/184-420 AC A0A7L3VKX5.1
#=GS A0A7N4NX73_SARHA/185-420 AC A0A7N4NX73.1
#=GS H0W2Z8_CAVPO/185-419 AC H0W2Z8.2
#=GS A0A0R3W4J4_TAEAS/308-459 AC A0A0R3W4J4.1
#=GS A0A5N5TDW8_9CRUS/191-337 AC A0A5N5TDW8.1
#=GS A0A8C4WAW1_9SAUR/227-462 AC A0A8C4WAW1.1
#=GS A0A3P9P1J9_POERE/417-652 AC A0A3P9P1J9.1
#=GS A0A7L2R9V3_9PASS/184-419 AC A0A7L2R9V3.1
#=GS A0A7L3EXD7_9PASS/184-420 AC A0A7L3EXD7.1
#=GS A0A553PHY5_TIGCA/183-377 AC A0A553PHY5.1
#=GS A0A3P8WJ70_CYNSE/174-401 AC A0A3P8WJ70.1
#=GS A0A8C9CPM1_PHOSS/185-419 AC A0A8C9CPM1.1
#=GS A0A7K4SHH0_9CHAR/184-420 AC A0A7K4SHH0.1
#=GS A0A7M7HPK0_STRPU/187-434 AC A0A7M7HPK0.1
#=GS A0A7L1SHA2_ARAGA/184-420 AC A0A7L1SHA2.1
#=GS A0A7L2IBW2_9PICI/184-420 AC A0A7L2IBW2.1
#=GS A0A850XP30_PIACA/1-232 AC A0A850XP30.1
#=GS A0A267FWZ0_9PLAT/315-483 AC A0A267FWZ0.1
#=GS A0A7K7EQP9_9SYLV/184-419 AC A0A7K7EQP9.1
#=GS A0A7L3NTD4_9DEND/163-394 AC A0A7L3NTD4.1
#=GS A0A2K6CIK3_MACNE/186-420 AC A0A2K6CIK3.1
#=GS A0A7J7JIS0_BUGNE/253-407 AC A0A7J7JIS0.1
#=GS A0A7K8SXH4_9AVES/184-420 AC A0A7K8SXH4.1
#=GS A0A8I3NSS2_CANLF/185-367 AC A0A8I3NSS2.1
#=GS A0A7K9UMG5_ANSSE/184-420 AC A0A7K9UMG5.1
#=GS A0A5N4D494_CAMDR/412-646 AC A0A5N4D494.1
#=GS A0A7J7T3V1_MYOMY/164-398 AC A0A7J7T3V1.1
#=GS A0A7L1VD50_SITEU/184-420 AC A0A7L1VD50.1
#=GS A0A7L3WRC1_9GRUI/184-420 AC A0A7L3WRC1.1
#=GS A0A672JXP8_SINGR/198-434 AC A0A672JXP8.1
#=GS A0A3M0JKX3_HIRRU/235-470 AC A0A3M0JKX3.1
#=GS A0A813W2G4_9BILA/195-351 AC A0A813W2G4.1
#=GS A0A1U7R749_MESAU/185-419 AC A0A1U7R749.1
#=GS A0A164XAS6_9CRUS/18-162 AC A0A164XAS6.1
#=GS A0A2K5X8R5_MACFA/264-498 AC A0A2K5X8R5.2
#=GS A0A4W6CU94_LATCA/489-724 AC A0A4W6CU94.1
#=GS A0A7K5MVJ1_CARCD/184-420 AC A0A7K5MVJ1.1
#=GS A0A852N3X7_9PASS/184-420 AC A0A852N3X7.1
#=GS A0A8C8M133_ONCTS/425-660 AC A0A8C8M133.1
#=GS A0A851XG02_EOLRO/184-420 AC A0A851XG02.1
#=GS A0A4Y2RVA8_ARAVE/183-332 AC A0A4Y2RVA8.1
#=GS A0A6P5J252_PHACI/165-397 AC A0A6P5J252.1
#=GS A0A673VIN0_SURSU/185-419 AC A0A673VIN0.1
#=GS A0A7K8HJF1_9CORV/184-420 AC A0A7K8HJF1.1
#=GS A0A8C8RJM3_9SAUR/185-419 AC A0A8C8RJM3.1
#=GS A0A6P8ZZY3_THRPL/304-432 AC A0A6P8ZZY3.1
#=GS A0A3Q2H7C1_HORSE/185-374 AC A0A3Q2H7C1.1
#=GS A0A1L8EKI6_XENLA/168-400 AC A0A1L8EKI6.1
#=GS A0A6J3QM39_TURTR/185-419 AC A0A6J3QM39.1
#=GS A0A6P6JXS9_CARAU/173-410 AC A0A6P6JXS9.1
#=GS A0A1W0WMG9_HYPDU/255-468 AC A0A1W0WMG9.1
#=GS A0A7J7EQM0_DICBM/185-419 AC A0A7J7EQM0.1
#=GS A0A8B7ISS3_9AVES/166-402 AC A0A8B7ISS3.1
#=GS A0A8C4LKE6_EQUAS/185-419 AC A0A8C4LKE6.1
#=GS A0A8B9M8Z5_9AVES/166-402 AC A0A8B9M8Z5.1
#=GS A0A7K7BEI5_9AVES/184-420 AC A0A7K7BEI5.1
#=GS A0A6P9A0S0_THRPL/272-401 AC A0A6P9A0S0.1
#=GS A0A183T6X5_SCHSO/873-1047 AC A0A183T6X5.1
#=GS A0A452CDT8_BALAS/183-417 AC A0A452CDT8.1
#=GS A0A7K8KAR2_9GRUI/184-420 AC A0A7K8KAR2.1
#=GS A0A7L3FYI4_9GRUI/184-420 AC A0A7L3FYI4.1
#=GS A0A819J9Z1_9BILA/550-699 AC A0A819J9Z1.1
#=GS A0A7K5TKW0_CEPOR/184-420 AC A0A7K5TKW0.1
#=GS A0A7E6FKJ0_OCTVU/175-301 AC A0A7E6FKJ0.1
#=GS A0A158QI86_RODNA/290-431 AC A0A158QI86.1
#=GS A0A813W2I2_9BILA/398-492 AC A0A813W2I2.1
#=GS W6U694_ECHGR/339-474 AC W6U694.1
#=GS A0A8C3V0W9_CATUS/166-402 AC A0A8C3V0W9.1
#=GS A0A8C5D822_9TELE/174-402 AC A0A8C5D822.1
#=GS A0A226N7X2_CALSU/184-418 AC A0A226N7X2.1
#=GS A0A813UVU7_9BILA/205-433 AC A0A813UVU7.1
#=GS A0A6P9A0S0_THRPL/114-257 AC A0A6P9A0S0.1
#=GS A0A7K8C783_9CORV/184-420 AC A0A7K8C783.1
#=GS A0A7L3NFF0_9AVES/184-420 AC A0A7L3NFF0.1
#=GS A0A2I3GGC6_NOMLE/188-422 AC A0A2I3GGC6.1
#=GS A0A7K8GM21_ORTSP/185-418 AC A0A7K8GM21.1
#=GS A0A8C4TQ04_ERPCA/179-412 AC A0A8C4TQ04.1
#=GS A0A4U1FHC8_MONMO/184-418 AC A0A4U1FHC8.1
#=GS A0A212D795_CEREH/287-477 AC A0A212D795.1
#=GS A0A8C6DTT3_MOSMO/185-419 AC A0A8C6DTT3.1
#=GS A0A7K6M2X4_PANBI/184-419 AC A0A7K6M2X4.1
#=GS A0A6P8ZZZ4_THRPL/139-282 AC A0A6P8ZZZ4.1
#=GS H3AI61_LATCH/192-417 AC H3AI61.1
#=GS A0A8D0H8W3_SPHPU/186-422 AC A0A8D0H8W3.1
#=GS A0A4U5VU41_COLLU/1210-1325 AC A0A4U5VU41.1
#=GS A0A2T7PX93_POMCA/133-294 AC A0A2T7PX93.1
#=GS A0A4Y2PC14_ARAVE/198-329 AC A0A4Y2PC14.1
#=GS L9JWJ6_TUPCH/169-403 AC L9JWJ6.1
#=GS A0A6P7ISG0_9TELE/446-677 AC A0A6P7ISG0.1
#=GS A0A8B9XH72_BOSMU/185-419 AC A0A8B9XH72.1
#=GS A0A8C5PHP0_9ANUR/225-457 AC A0A8C5PHP0.1
#=GS V3ZZE5_LOTGI/175-320 AC V3ZZE5.1
#=GS A0A7K7ZHJ4_9PASE/184-420 AC A0A7K7ZHJ4.1
#=GS A0A4Z2CRJ6_SCHJA/343-507 AC A0A4Z2CRJ6.1
#=GS A0A7K8Y499_9PICI/184-420 AC A0A7K8Y499.1
#=GS A0A7L3GET9_9AVES/184-420 AC A0A7L3GET9.1
#=GS A0A3N0Y262_ANAGA/202-438 AC A0A3N0Y262.1
#=GS A0A1D2ME66_ORCCI/230-337 AC A0A1D2ME66.1
#=GS A0A7L0Z5K2_9PASE/184-420 AC A0A7L0Z5K2.1
#=GS A0A6P3EXE0_OCTDE/165-399 AC A0A6P3EXE0.1
#=GS A0A7K4JT44_GEOCA/184-271 AC A0A7K4JT44.1
#=GS A0A2K6SY07_SAIBB/166-400 AC A0A2K6SY07.1
#=GS A0A819J9Z1_9BILA/724-849 AC A0A819J9Z1.1
#=GS A0A7L0CG50_9AVES/184-420 AC A0A7L0CG50.1
#=GS A0A7L2AYJ5_9GRUI/184-420 AC A0A7L2AYJ5.1
#=GS M3WWG3_FELCA/185-420 AC M3WWG3.1
#=GS A0A5B7DB40_PORTR/147-239 AC A0A5B7DB40.1
#=GS A0A8C6QJ69_NANGA/185-419 AC A0A8C6QJ69.1
#=GS A0A8C2W2U1_CHILA/184-418 AC A0A8C2W2U1.1
#=GS A0A6P4Y6U6_BRABE/418-508 AC A0A6P4Y6U6.1
#=GS A0A7K9L3K3_9PASS/184-420 AC A0A7K9L3K3.1
#=GS A0A8B8DBY4_CRAVI/274-494 AC A0A8B8DBY4.1
#=GS A0A091W9Z2_OPIHO/185-425 AC A0A091W9Z2.1
#=GS A0A7J8G6V2_ROUAE/184-416 AC A0A7J8G6V2.1
#=GS M4A320_XIPMA/462-696 AC M4A320.2
#=GS A0A093PW50_9PASS/185-418 AC A0A093PW50.1
#=GS A0A7L1AXZ3_GYMTI/184-420 AC A0A7L1AXZ3.1
#=GS A0A834FNX5_ORYME/10-59 AC A0A834FNX5.1
#=GS A0A8C7WN67_9TELE/400-634 AC A0A8C7WN67.1
#=GS A0A452SI29_URSAM/165-349 AC A0A452SI29.1
#=GS A0A0N8JW05_SCLFO/445-669 AC A0A0N8JW05.1
#=GS A0A2K5M7R8_CERAT/186-420 AC A0A2K5M7R8.1
#=GS A0A6J3I0U9_SAPAP/239-473 AC A0A6J3I0U9.1
#=GS A0A7L1Y5Q3_9PASS/184-420 AC A0A7L1Y5Q3.1
#=GS C0H9F4_SALSA/445-680 AC C0H9F4.1
#=GS A0A852LC26_UROIN/148-384 AC A0A852LC26.1
#=GS A0A8J2RXV1_9CRUS/230-334 AC A0A8J2RXV1.1
#=GS A0A093HUC2_TYTAL/185-412 AC A0A093HUC2.1
#=GS A0A7K8ZXI5_9PASS/184-420 AC A0A7K8ZXI5.1
#=GS A0A3Q4HUT6_NEOBR/403-635 AC A0A3Q4HUT6.1
#=GS A0A813W2G4_9BILA/396-490 AC A0A813W2G4.1
#=GS A0A7K8R577_9PASS/184-420 AC A0A7K8R577.1
#=GS A0A7K5CWB3_9TYRA/184-420 AC A0A7K5CWB3.1
#=GS A0A2K6CIK6_MACNE/166-400 AC A0A2K6CIK6.1
#=GS A0A3Q3BND8_KRYMA/410-640 AC A0A3Q3BND8.1
#=GS H2QD09_PANTR/186-420 AC H2QD09.1
#=GS A0A553N331_9TELE/179-415 AC A0A553N331.1
#=GS A0A091ICP6_CALAN/185-418 AC A0A091ICP6.1
#=GS T1F2S8_HELRO/342-445 AC T1F2S8.1
#=GS A0A4W4FPE1_ELEEL/169-402 AC A0A4W4FPE1.1
#=GS A0A8C9GZ39_9PRIM/186-420 AC A0A8C9GZ39.1
#=GS H2NU17_PONAB/174-408 AC H2NU17.2
#=GS A0A7J7U7R7_PIPKU/164-398 AC A0A7J7U7R7.1
#=GS CN37_RAT/185-419 AC P13233.2
#=GS A0A6P5DFF7_BOSIN/185-419 AC A0A6P5DFF7.1
#=GS A0A850V3C2_9CORV/184-420 AC A0A850V3C2.1
#=GS K7FS99_PELSI/185-420 AC K7FS99.1
#=GS A0A7L1ZUU1_LEILU/184-419 AC A0A7L1ZUU1.1
#=GS A0A8C8B8R2_9STRI/185-421 AC A0A8C8B8R2.1
#=GS A0A8U0S756_MUSPF/185-419 AC A0A8U0S756.1
#=GS A0A851UN34_9PASS/184-420 AC A0A851UN34.1
#=GS A0A814E0I0_9BILA/178-400 AC A0A814E0I0.1
#=GS A0A7K6N2W2_PEDTO/248-384 AC A0A7K6N2W2.1
#=GS A0A8C2W6Y4_CHILA/165-399 AC A0A8C2W6Y4.1
#=GS A0A6P9BW98_PANGU/184-421 AC A0A6P9BW98.1
#=GS A0A671T6W3_9TELE/187-421 AC A0A671T6W3.1
#=GS A0A5B7DB40_PORTR/11-125 AC A0A5B7DB40.1
#=GS A0A7J7U7V1_PIPKU/184-418 AC A0A7J7U7V1.1
#=GS A0A075A175_9TREM/320-504 AC A0A075A175.1
#=GS A0A8C7INS6_ONCKI/649-884 AC A0A8C7INS6.1
#=GS A0A7K6XD83_9PASE/184-420 AC A0A7K6XD83.1
#=GS A0A8I3NGU6_CANLF/185-419 AC A0A8I3NGU6.1
#=GS A0A7J8G5V5_ROUAE/164-255 AC A0A7J8G5V5.1
#=GS A0A4W3ID06_CALMI/251-469 AC A0A4W3ID06.1
#=GS A0A2Y9QP74_TRIMA/185-419 AC A0A2Y9QP74.1
#=GS A0A6J8DEH1_MYTCO/405-603 AC A0A6J8DEH1.1
#=GS A0A7L0H1I0_HERCA/184-420 AC A0A7L0H1I0.1
#=GS A0A2Y9EC14_TRIMA/165-399 AC A0A2Y9EC14.1
#=GS A0A7M4EBY6_CROPO/185-421 AC A0A7M4EBY6.1
#=GS A0A7J8G6B4_ROUAE/184-418 AC A0A7J8G6B4.1
#=GS A0A1V4JQL8_PATFA/185-421 AC A0A1V4JQL8.1
#=GS A0A7K6BWU1_PTIVI/184-420 AC A0A7K6BWU1.1
#=GS A0A851SG31_CERFA/184-420 AC A0A851SG31.1
#=GS A0A7K6GA79_9PASS/184-420 AC A0A7K6GA79.1
#=GS A0A8C9FLE6_PAVCR/296-496 AC A0A8C9FLE6.1
#=GS A0A7L1NL07_RHICY/184-420 AC A0A7L1NL07.1
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A0A7L2XTT0_9PASS/184-420 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.S..K.....YF....pS.A.I.E..D.P.K....IK...T.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..E.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AS.Y.GKGFTLSISALFITTK.TVGARIDLS.E.QQ..L...LLW..P.G.D...ADK.................................IL.PT.....D.....NL..P.R....GSRAHITLGCANGVEAVQTGLDLLEF.VKLE.K....A..G...N...K.....G.......E....QV...G...EI...G..G...G..K..L.....LYF...D.NG.....MWMLVLSKKIDVRAIFSGYYGK.GKLV.P..T.QST.NKRGSAFSS..CTI....................................................
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#=GR A0A7K5ETD6_POLCE/184-420 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A671XM69_SPAAU/502-733 ......................................................LPLYFGWFLLS.S.VQDK.V.R.C.TS.M.D..F.L.KT..L....D.TL.EAFKK.H.L..I.....DF.....-.-.T.G..K.A.E....KE...V.D.....LE....QY.F....-..-.......Q....A....K..G...T..LHCTTKFC..D.Y.G..K..A..EG...A...K.....E...YA.....Q.....IPAV.N.DL.Y.GSVFELSLSALFVTPR.TVGARVSLT.E.EQ..L...VLW..P.A.D...AEK................................eVE.SA.....A.....SL..P.L....GSRAHVTLGCAEGVEPVQTGLDLLDI.LALQ.Q....G..G...Q...Q.....G.......E....LV...E...EM...E..L...G..S..L.....TYY...G.EG.....RWLLSLREPICAPACFSSFYEC.KGLE.L..T.AKG.PEKKKKQK-..CAI....................................................
#=GR A0A671XM69_SPAAU/502-733 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A4Z2CRP2_SCHJA/342-444 ...............................iqdvlthwesatvpnfgtglkac-----------.-.----.-.-.-.--.-.-..-.-.--..-....-.--.-----.-.-..-.....--.....-.-.-.-..-.-.-....--...-.-.....--....--.-....-..-.......S....T....P..S...I..PHITAMYS..K.Y.G..R..A..FG...A...E.....Y...YA.....L.....RRSV.N.ETlL.GKLFTVQITGLVISPR.TIGARVKLP.N.DE..Vi.rHLW..A.S.D...DQE.................................--.--.....-.....--..-.-....--------------------------.----.-....-..-...-...-.....-.......-....--...-...--...-..-...-..-..-.....---...-.--.....----------------------.----.-..-.---.---------..---vvfpg...............................................
A0A8C0H7H2_CHEAB/213-448 ......................................................LPLYYGWFLSK.K.SSEN.L.R.K.TG.Q.A..F.L.DE..L....G.SL.KVFKK.E.S..K.....YF.....L.P.A.E..D.P.K....IK...L.D.....LT....SY.F....A..K.......R....P....P..S...V..LHCTTKFT..D.F.G..K..A..MG...A...D.....E...YA.....Q.....QEVV.K.AS.Y.GKAFTLTISALFVTTK.TAGARVELS.E.QE..L...LLW..P.G.D...VDK.................................IL.PA.....D.....NL..P.K....GSRAHITLGCASGIEPVQTGIDLLEF.VKLE.K....A..G...T...K.....G.......D....EI...E...EV...G..G...G..K..L.....QYF...G.NG.....MWMLLLSKKIEVKAIFSGYYGK.GKLV.P..T.QGS.NKRGSAFNP..CTI....................................................
#=GR A0A8C0H7H2_CHEAB/213-448 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A158QDL9_HYMDI/258-395 ..............................................sithvsrp-----------.-.----.-.-.-.--.-.-..-.-.--..-....-.--.-----.-.-..-.....--.....-.-.-.-..-.-.-....--...-.-.....--....--.-....-..-.......-....-....-..-...-..-HCTAFFS..N.F.G..R..A..TG...A...I.....E...YT.....N.....RSAV.R.EG.LlGLVQSICLEGLFITKR.TVGLKVKLSgD.EQ..M...NLW..G.GlDdepVDG.................................YA.PD.....E.....PR..P.K....GCRAHITLALAPGISPVETGFDALRI.ADSE.-....-..-...-...-.....-.......-....--...-...--...-..-...-..-..-.....---...-.--.....----------------------.----.-..-.---.---------..---llsrpdvthveltegiire.................................
#=GR A0A158QDL9_HYMDI/258-395 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A8C6YQI3_NOTPE/186-422 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.TG.Q.A..F.L.DE..L....G.SL.KNFKK.E.S..K.....YF....aP.A.I.E..D.P.K....IK...I.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..D.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AA.Y.GRGFTLSISALFVTPK.TVGARVELS.E.QQ..L...PLW..P.A.D...ADK.................................VT.PA.....D.....NL..P.K....GSRAHVTLGCASGVEAVQTGLDLLEF.VKLE.K....A..G...N...K.....G.......E....DM...G...VL...G..G...G..K..L.....QYF...N.NG.....MWMLVLSKKVDVRAIFSGYYGK.GKLV.P..T.QST.NKRGSAFSS..CTI....................................................
#=GR A0A8C6YQI3_NOTPE/186-422 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
H0YW77_TAEGU/185-418 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.I..P.....SA.....-.-.I.E..D.P.K....IK...I.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..E.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AS.Y.GKAFTLSISALFITTK.TVGARIELS.E.QQ..L...QLW..P.G.D...ADK.................................IL.PT.....D.....NL..P.R....GSRAHITLGCANGVEAVQTGLDLLEF.VKLE.K....A..G...N...K.....G.......E....QV...G...EI...G..G...G..K..L.....LYF...D.NG.....MWMLVLSKKIDVRAIFSGYYGK.GKLV.P..T.QST.NKRGAAFSS..CTI....................................................
#=GR H0YW77_TAEGU/185-418 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
E9H290_DAPPU/16-162 ......................................................LPLYYGWFVET.EySSSF.L.N.R.SR.K.M..L.A.DT..L....Q.EI.PDFLK.D.V..Q.....NF.....-.-.T.Q..K.T.Y....IT...D.I.....LL....HY.T....R..E.......N....A....D..E...V..LHCTAMYN..G.V.SpnY..V..PG...A...Q.....E...YS.....E.....KQVV.K.DN.L.NQVSTLHSIGWILTPR.TFGARIKLT.K.NQ..L...LVW..NqN.D...TEG.................................--.--.....-.....--..-.-....--------------------------.----.-....-..-...-...-.....-.......-....--...-...--...-..-...-..-..-.....---...-.--.....----------------------.----.-..-.---.---------..---npkqakvnsktfit......................................
A0A3Q7N7G2_CALUR/185-419 ......................................................LPLYFGWFLTK.K.SSES.L.R.K.AG.Q.A..F.L.EE..L....S.NH.KAFKK.E.L..R.....HF.....V.S.G.D..E.P.R....EK...I.E.....LV....TY.F....G..K.......R....P....P..G...V..LHCTTKFC..D.Y.G..K..A..AG...A...D.....E...YA.....Q.....QDVV.K.KS.Y.CKAFTLTVTALFVTPK.TTGARVELS.E.QE..L...PLW..P.N.D...VDK.................................LS.PS.....D.....SL..P.R....GSRAHITLGCAGDVEPVQTGIDLLEI.VRQE.K....G..G...S...R.....G.......E....EV...G...EL...S..R...G..K..L.....YSL...G.NG.....RWLLSLAKKLEVRAIFTGYYGK.GKPV.P..T.HGS.RKGGALQS-..CTI....................................................
#=GR A0A3Q7N7G2_CALUR/185-419 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A484CH76_PERFV/484-714 ......................................................LPLYFGWFLLS.S.IQDK.V.R.C.TA.M.D..F.L.KT..L....D.TL.EAFKK.H.L..I.....DF.....-.-.T.G..K.A.E....KE...V.D.....LE....QY.F....-..-.......E....A....K..G...T..LHCTTKFC..D.Y.G..K..A..EG...A...K.....D...YA.....E.....KPAV.K.DF.Y.GSAFELSLSALFVTPR.TVGARVSLT.E.EQ..L...LLW..P.A.D...AEK.................................EA.GS.....A.....SL..P.L....GSRAHVTLGCAEGVEPVQTGLDLLEI.LALQ.Q....E..G...H...Q.....G.......E....LI...E...EM...E..L...G..S..L.....TYY...G.EG.....RWLLSLREPICSSACFSSFYGR.KELD.P..A.KKE.PEKKKKPK-..CTI....................................................
#=GR A0A484CH76_PERFV/484-714 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A7K5V6B9_9CORV/184-420 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.S..K.....HF....pS.A.A.E..D.P.K....IK...T.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..E.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AS.Y.GKGFTLSISALFITTK.TVGARIELS.E.QQ..L...LLW..P.G.D...ADK.................................IL.ST.....D.....NL..P.R....GSRAHITLGCANGVEAVQTGLDLLEF.VKLE.K....A..G...N...K.....G.......E....QV...G...EI...G..G...G..K..L.....LYF...D.NG.....MWMLVLSKKIDVRAIFSGYYGK.GKLV.P..T.QST.NKRGSAFSS..CTI....................................................
#=GR A0A7K5V6B9_9CORV/184-420 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A087UHT7_STEMI/192-337 ....................................................qh--LFCAWFLHE.K.DSVE.L.R.N.EA.E.L..Y.VrDC..F....E.NS.IDFKD.Y.F..S.....KI.....C.S.V.E..D.F.R....TH...Y.N.....LH....H-.-....-..-.......K....R....Q..D...L..AYCMTAM-..-.F.R..S..I..ID...T...H.....A...YF.....R.....EESV.Q.KF.Y.GKMAKLFIVGFIVSPH.MIAARVKLT.Q.EQ..K...KLWklP.N.D...LEE.................................SC.PI.....-.....--..-.-....--------------------------.----.-....-..-...-...-.....-.......-....--...-...--...-..-...-..-..-.....---...-.--.....----------------------.----.-..-.---.---------..---svypseliekskvk......................................
A0A8J6A539_GALPY/193-427 ......................................................LPLFFGWFLSR.K.SSEN.L.R.K.AG.Q.A..F.L.SE..L....G.NH.KAFKK.E.L..R.....QF.....V.P.G.D..E.S.R....EK...I.D.....LV....TY.F....G..K.......R....P....P..G...V..LHCTTKFC..N.Y.G..K..A..PG...A...E.....D...YA.....M.....QDVV.K.KS.Y.CKAFTLTISALFVTPK.TTGARVELS.E.QE..L...PLW..P.N.D...VDM.................................VV.AS.....D.....NL..P.R....GSRAHITLGCAGDVEAVQTGLDLLDI.VRQE.K....G..G...N...R.....G.......E....EV...G...EL...N..R...G..R..L.....YNL...G.SG.....RWMLNLAKKMEVRAIFTGYYGK.GKPV.P..T.HGA.QKGRAMQS-..CTI....................................................
#=GR A0A8J6A539_GALPY/193-427 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A7K7R4D6_POEAT/184-420 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.S..K.....YF....pS.A.I.E..D.P.K....IK...I.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..E.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AS.Y.GKGFTLSISALFITTK.TVGARIELS.E.QQ..L...LLW..P.G.D...ADK.................................IL.PT.....D.....NF..P.R....GSRAHITLGCANGVEAVQTGLDLLEF.VKLE.K....A..G...N...K.....G.......E....QV...G...EI...G..G...G..K..L.....LYF...D.NG.....MWMLVLSKKIDVRAIFSGYYGK.GKLV.P..T.QST.NKRGSAFSS..CTI....................................................
#=GR A0A7K7R4D6_POEAT/184-420 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A452SI93_URSAM/165-399 ......................................................LPLYFGWFLTK.K.SSES.L.R.K.AG.Q.A..F.L.EE..L....G.NH.KAFKK.E.L..R.....HF.....V.S.G.D..E.P.R....EK...I.E.....LV....TY.F....G..K.......R....P....P..G...V..LHCTTKFC..D.Y.G..K..A..AG...A...D.....E...YA.....Q.....QDVV.K.KS.Y.CKAFTLTITALFVTPK.TTGARVQLS.E.QE..L...PLW..P.N.D...VDK.................................LS.PS.....D.....SL..P.R....GSRAHITLGCAGDVEPVQTGIDLLEI.VRQE.K....G..G...S...R.....G.......E....EV...G...EL...H..R...G..K..L.....YSL...G.NG.....RWLLSLAKKLEVRAIFTGYYGK.GKPV.P..A.HGS.RKGGALQS-..CTI....................................................
#=GR A0A452SI93_URSAM/165-399 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A6I8P9T5_ORNAN/184-418 ......................................................LPLYFGWFLSK.R.SSES.L.R.K.AG.Q.A..F.L.DE..L....S.IH.KAFRK.E.L..R.....HF.....V.S.G.D..E.P.K....DK...V.D.....LA....AY.F....V..K.......R....P....P..G...V..LHCTTKFC..D.Y.G..R..A..AG...A...D.....E...YA.....Q.....QDVV.K.QA.Y.ARAFSLTISALFVTPR.TAGARVELS.D.RE..L...PLW..P.A.D...VDR.................................LT.PA.....E.....AL..P.R....GSRAHVTLGCAGGVEPVQTGIDLLEL.VRQE.K....V..G...P...P.....A.......E....EV...G...EL...G..R...G..R..L.....VAY...G.NG.....RWLLRLAKKMEVRAIFTGYYGR.GQAV.P..T.QGP.RKGGAFRS-..CTV....................................................
#=GR A0A6I8P9T5_ORNAN/184-418 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A6P7IVQ5_9TELE/459-690 ......................................................LPLYFGWFLLS.S.IQDK.I.E.C.TA.M.D..F.L.KT..L....D.TL.EAFKK.H.S..S.....DF.....-.-.T.G..K.P.E....KE...V.D.....LE....QY.F....-..-.......E....A....K..G...V..LHCTTKFC..D.Y.G..N..A..EG...A...K.....D...YA.....Q.....KTAV.K.EF.Y.GSVFELSLSALFVTPR.TVGARVSLT.E.EQ..L...VLW..P.A.D...AES................................vVP.AA.....A.....SL..P.L....GSRAHVTLGCANGVEPVQTGLDLLEI.LLLQ.Q....E..G...Q...Q.....G.......E....LV...E...EM...E..L...G..S..L.....TYY...G.EG.....RWLLNLREPICVPACFSSFFGC.KEQE.P..T.KKE.PEKKKKPK-..CTI....................................................
#=GR A0A6P7IVQ5_9TELE/459-690 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
Q6GPR2_XENLA/167-399 ......................................................LPLYFGWFLAK.R.DEDN.L.R.K.TA.H.E..F.L.EQ..L....G.NL.KAFKK.R.L..Q.....AF.....-.-.G.R..E.D.K....HK...L.D.....LL....KY.F....A..-.......K....T....P..N...I..LHCTTKFC..D.Y.G..K..M..PG...S...E.....E...YA.....Q.....LEAV.R.KG.Y.SKAFTLHISALFITPR.TAGAQVELT.Q.EQ..L...HVW..P.S.D...AER................................eAM.PK.....D.....VL..P.R....GSRAHITLGCAADVQDVQTGIDLLEF.VKLQ.Q....A..G...R...E.....G.......E....NM...G...EL...L..G...S..K..I.....SYY...D.NG.....MWMLALPRKKEIKTIFSGYYGK.PGVT.G..P.HLG.GKKGL----..---lpqcqi..............................................
#=GR Q6GPR2_XENLA/167-399 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A8C3S6E0_CHESE/227-462 ......................................................LPVYYGWFLSK.K.SSEN.L.R.K.TG.Q.A..F.L.DE..L....G.SL.KVFKK.E.S..K.....YF.....L.P.A.E..D.P.K....VK...L.D.....LT....SY.F....A..K.......R....P....P..G...V..LHCTTKFT..D.F.G..K..A..MG...A...D.....E...YA.....Q.....QEVV.K.AS.Y.GKAFTLTISALFLTTK.TAGARVELS.E.QE..L...LLW..P.G.D...VDK.................................IL.PT.....D.....NL..P.K....GSRAHITLGCASGIDPVQTGIDLLEF.VKLE.K....A..G...N...K.....G.......D....DI...E...EV...G..G...G..K..L.....QYF...G.NG.....MWMLLLSKKIEVKALFSGYYGK.GKLV.P..T.QGS.NKRGSAFNP..CTI....................................................
#=GR A0A8C3S6E0_CHESE/227-462 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A7L3LDD6_9CHAR/184-420 ......................................................LPMYFGWFLSK.R.SSEM.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.S..K.....FF....aS.A.I.E..D.P.K....IK...L.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..D.F.G..K..A..PG...A...E.....E...YA.....Q.....QEAV.R.AA.Y.GKGFTLAISAFFLTPK.TAGARVELS.E.QQ..L...LLW..P.G.D...SDK.................................VL.PS.....D.....SL..A.R....GSRAHITLGCASGIEAVQTGLDLLEF.VKLE.K....A..G...N...K.....G.......E....QV...G...EI...G..G...G..K..L.....LYF...E.NG.....MWMLTLAKKLDVRAIFSGYYGK.GKLV.P..T.QST.NKRSSAFSS..CTI....................................................
#=GR A0A7L3LDD6_9CHAR/184-420 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A8C4Q9S2_EPTBU/155-390 .....................................................i-ALFYGWFLTK.K.SVDC.L.L.E.YY.K.S..F.L.ED..L....Q.KR.PLFLE.E.T.iS.....TF.....-.T.P.G..D.Q.K....LP...P.I.....LD....IY.F....S..R.......S....KfsggR..N...L..LHCTANFT..D.Y.G..Q..T..PG...A...A.....N...YV.....K.....S---.-.SG.L.GRAFKLQLTALFVTPR.TVGARVKLS.R.AQ..L...PLF..N.F.D...ESV.................................SE.PT.....T.....GD..P.VtpdpGSRAHVTLGCAPNVEPVQTGLDLMDI.LRSI.E....G..D...E...K.....P.......S....IT...L...NM...D..L...G..K..L.....CCY...G.KG.....RWMLDLTKPIPVNSLFSGFYAK.SPPN.D..D.S--.---------..---ashtlcekes..........................................
#=GR A0A8C4Q9S2_EPTBU/155-390 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A1S3HX97_LINUN/173-314 ......................................................IPLYYAWFLNY.P.DSEM.I.L.Q.QG.M.S..V.Y.QE.cF....T.KV.DQFRE.C.I..K.....NN.....I.G.F.G..E.N.R....GS...-.-.....AR....NY.Y....S..R.......E....Gf.agG..N...K..LHCTAKFC..G.K.G..K..V..PG...S...G.....D...YA.....R.....SDIV.Q.QS.M.NRSSSLEIIGIVLTPK.TLTARVRLS.K.EQ..L...KLW..G.N.E...DD-.................................--.--.....-.....--..-.-....--------------------------.----.-....-..-...-...-.....-.......-....--...-...--...-..-...-..-..-.....---...-.--.....----------------------.----.-..-.---.---------..---lkrdkddgal..........................................
A0A8C2ZUU2_CYCLU/446-676 ......................................................IPLYFGWFLLS.S.IQDK.V.R.C.TS.M.D..F.L.KT..L....D.TL.EAFKK.H.L..I.....DF.....-.-.T.G..K.A.E....KE...V.D.....LE....QY.F....-..-.......Q....A....K..G...T..LHCTTEFC..D.Y.G..K..V..EG...S...K.....E...YA.....N.....NPAV.K.ES.Y.GSAFELSLSALFVTPR.TVGARVSLS.E.EQ..L...LLW..P.A.D...AEK.................................EG.ES.....A.....SL..P.L....GSRAHVTLGCAEGVEPVQTGLDLLQI.LALQ.Q....E..G...Q...Q.....G.......E....LI...E...EM...E..L...G..S..L.....TYY...G.EG.....RWLLGLREPICAPACFSSFYGR.KELD.P..T.KKE.PEKKKKPK-..CAI....................................................
#=GR A0A8C2ZUU2_CYCLU/446-676 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A851A353_SULDA/184-420 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.G..F.L.DE..L....G.SL.KAFKK.E.S..K.....YF....aS.A.I.E..D.P.K....IK...I.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..D.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AS.Y.GKGFTLSISALFITTK.TAGARVELS.E.QQ..L...PLW..P.A.D...ADK.................................IL.PT.....D.....NL..P.K....GSRAHITLGCANSIEAVQTGLDLLEI.VKLE.K....A..G...N...K.....G.......D....EV...G...EI...G..G...G..K..L.....LYF...D.NG.....MWMLILSKKIDVKAVFSGYYGK.GKLV.P..T.QST.NKRGSAFSS..CTI....................................................
#=GR A0A851A353_SULDA/184-420 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A8J5AMJ5_9DIPT/23-276 .....................................................s-PYFYGWFFNE.T.VASG.L.I.Q.IT.T.N..Y.L.TK..L...yA.DV.EEVQK.F.L..R.....NV.....S.T.T.A..D.I.D....NP...-.-.....LL....-Y.Y....T..KpvdpntgD....Y....D..K...Y..FHITTFYC..-.-.G..T..A..D-...C...S.....N...YT.....K.....Q--V.T.QY.I.DQAFTTHLVGVYFTPR.TYGIRVNLT.S.VQ..R...EIF..D.L.N...EANavtlsrfnrnaep.......cdvqlvngiqfcpQD.DT.....N.....FH..P.T....NTRAHVTLGCAPNISAVTTGLDLIEI.LNLE.M....N..P...S...Q.....F.......C....AQ...I...QI...D..E...G..N..L.....IQM...G.EKc...dIFVVYLKKKMVADSTFEAYYRS.D---.-..-.---.---------..---ailtmsvpcr..........................................
#=GR A0A8J5AMJ5_9DIPT/23-276 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
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A0A4Z2BXW5_9TELE/447-563 ....................................................np-----------.-.----.-.-.-.--.-.-..-.-.--..-....-.--.-----.-.-..-.....--.....-.-.-.-..-.-.-....--...-.-.....--....--.-....-..-.......-....-....-..-...-..--------..-.-.-..-..-..--...-...-.....-...--.....-.....----.-.--.-.----------------.---------.-.--..L...LLW..P.A.D...AEK................................eVE.GA.....S.....SL..P.L....GSRAHVTLGCAEGVEPVQTGLDLLEI.LAVQ.Q....G..G...Q...K.....G.......E....LV...E...EM...E..L...G..S..L.....SYY...G.EG.....RWLLSLREPIRTPACFSSVYGP.REVV.P..T.KKE.GEKKKKLK-..CS-i...................................................
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G3P201_GASAC/169-399 ......................................................IPLYYGWFLLS.S.IQDK.V.R.C.TS.M.D..F.L.KT..L....D.TL.EAFKK.H.L..I.....DF.....-.-.T.G..K.A.E....KE...V.D.....LE....QY.F....-..-.......E....A....K..G...T..LHCTTKFC..N.Y.G..K..V..EG...A...K.....E...YA.....Q.....NKAV.G.DF.Y.GSAFELSLSALFVTPR.TVGARVSLS.E.EQ..L...LLW..P.A.D...AEK.................................EA.GP.....A.....SL..P.P....GSRAHVTLGCAEGVEPVQTGLDLLEI.LALQ.Q....G..G...Q...Q.....G.......E....LI...E...EM...E..L...G..S..L.....TYY...G.EG.....RWLLSLREPIGALACFSSFYGP.RELE.V..L.KKE.PEKKKKPK-..CTI....................................................
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A0A8C5CQI3_GADMO/553-785 ......................................................IPLFFAWFLL-.-.-QDK.I.K.C.TA.M.D..F.L.KT..L....D.SL.DAFKK.H.L..A.....DF.....-.-.P.V..E.T.E....KE...V.D.....LE....QY.F....-..-.......K....S....N..W...S..LHCTTKYC..G.N.G..K..A..KG...A...K.....E...YA.....E.....QTAV.Q.DM.Y.GTVSELSLTALFVTPR.TVGARVSLS.E.AQ..L...ALW..P.A.D...AEKea............................eadVP.GA.....G.....AL..P.P....GSRAHISLGCAEKVQPVQTGLDLLDI.LVLL.Q....S..G...Q...Q.....G.......E....LV...E...EM...E..L...G..S..L.....VYL...D.KG.....RWLLTLREPISVQACFSSFYKP.KEAD.D..T.KRE.PEKKKKAK-..CS-i...................................................
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A0A6I8RTA0_XENTR/224-455 ......................................................LPLYFGWFLAK.R.DEDN.L.R.K.TA.H.E..F.L.EQ..L....G.NL.KAFKK.R.L..Q.....AF.....-.-.G.V..E.D.K....HK...L.D.....LL....KY.F....A..-.......K....T....P..N...I..LHCTTKFC..D.F.G..K..V..PG...S...E.....E...YA.....Q.....LEAV.R.KN.Y.SRGFTLHISALFVTPR.TAGAQIELT.Q.EQ..L...HLW..P.S.D...AEK................................eVM.PK.....D.....IL..P.R....GSRAHITLGCASDIQDVQTGIDLLEF.VKLQ.Q....A..G...R...E.....G.......E....NM...G...EL...L..G...G..K..I.....SYY...D.NG.....MWMLALPRKKEVKTIFSGYYGK.PGVT.A..P.HLG.KK-------..---gllpqcqi............................................
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A0A480ZVP3_PIG/185-419 ......................................................LPLYFGWFLSR.K.SSES.L.R.K.AG.Q.T..F.L.EE..L....G.NH.KAFKK.E.L..R.....HF.....G.S.G.D..E.P.R....EK...M.E.....LV....AY.F....G..K.......R....P....P..G...V..LHCTTKFC..D.Y.G..K..A..AG...A...E.....E...YA.....Q.....QEVV.K.KS.Y.SKAFVLTISALFVTPK.TTGARVELS.E.QE..L...ALW..P.N.D...VDK.................................LS.PS.....D.....SL..P.R....GSRAHITLGCAGDVEAVQTGLDLLEI.VRQE.K....G..G...S...R.....G.......E....EV...G...EL...S..R...G..K..L.....YSL...G.NG.....RWMLSLAKKMEVRAIFTGYYGK.GKAV.P..T.RGG.RKGGSFQS-..CAI....................................................
#=GR A0A480ZVP3_PIG/185-419 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A7L1RY96_9PASS/184-419 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.S..K.....YF.....P.S.A.E..D.P.K....IK...I.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..E.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AS.Y.GKGFTLSISALFITTK.TVGARIELS.E.QQ..L...LLW..P.G.D...ADK.................................IL.PT.....D.....NF..P.R....GSRAHITLGCANGVEAVQTGLDLLEF.VKLE.K....V..G...N...K.....G.......E....QV...G...EI...G..G...G..K..L.....LYF...D.NG.....MWMLVLAKKIDVRAIFSGYYGK.GKLV.P..T.QST.NKRGSAFTS..CTI....................................................
#=GR A0A7L1RY96_9PASS/184-419 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
F6W8L8_HORSE/185-374 ......................................................LPLYFGWFLTK.K.SSES.L.R.K.AG.Q.A..F.L.EE..L....G.NH.KAFKK.E.L..R.....QF.....V.P.G.D..E.P.R....EK...I.E.....LL....TY.F....G..K.......R....P....P..G...V..LHCTTKFC..D.Y.G..K..A..AG...A...E.....E...YA.....Q.....QDAV.K.KA.Y.GKAFMLTISALFVTPK.TTGARVELS.E.QE..L...LLW..P.N.D...VDK.................................LS.PS.....D.....SL..P.R....GSRAHITLGCAADVEAVQTGIDLLEI.VRQE.K....G..G...N...R.....G.......G....--...-...--...-..-...-..-..-.....---...-.--.....----------------------.----.-..-.---.---------..---flslaklkkevsw.......................................
#=GR F6W8L8_HORSE/185-374 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A852EC28_VIDMA/184-420 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.S..K.....YF....pS.A.I.E..D.P.K....IK...I.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..E.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AS.Y.GKGFTLSISALFITTK.TVGARIELS.E.QQ..L...LLW..P.G.D...ADK.................................IL.PT.....D.....NL..P.R....GSRAHITLGCANGVEAVQTGLDLLEF.VKLE.K....A..G...N...K.....G.......E....QV...G...EI...G..G...G..K..L.....LYF...D.NG.....MWMLVLSKKIDVRAIFSGYYGK.GKLV.P..T.QST.NKRGAAFSS..CTI....................................................
#=GR A0A852EC28_VIDMA/184-420 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A820C0A0_9BILA/392-488 ..................................nvsrsntteqvsflhptfgy-----------.-.----.-.-.-.--.-.-..-.-.--..-....-.--.-----.-.-..-.....--.....-.-.-.-..-.-.-....--...-.-.....--....--.-....-..-.......-....-....-..-...-..--------..-.-.-..-..-..--...-...-.....-...--.....-.....----.-.--.-.----------------.---------.-.--..-...---..-.-.-...---.................................--.--.....-.....--..-.-....LSRAHLTCGVAPGSSAAQTGQDIIEM.IQKE.S....D..T...I...Q.....R.......N...iPI...P...ESn.dE..R...T..V..M.....KYF...G.NG.....QCIVYLKEPMPVETIFSGCF--.----.-..-.---.---------..---h...................................................
A0A8C9DLL6_PROSS/54-288 ......................................................LPLYFGWFLTK.K.SSEA.L.R.K.AG.Q.I..F.L.EE..L....G.NH.KAFKK.E.L..P.....HF.....I.S.G.N..E.S.R....EK...I.D.....LV....TY.F....G..K.......R....P....P..G...V..LHCTTKFC..D.Y.G..K..A..TG...A...E.....E...YA.....Q.....QDVV.K.KS.Y.CKAFTLSISALFVTPK.TTGARVELS.E.QE..L...QLW..P.S.D...VDK.................................QT.PS.....D.....NL..P.R....GSRAHITLGCAADVEAVQTGLDLLEI.VRQE.K....G..G...N...R.....G.......E....EV...G...EL...S..R...G..K..L.....YSL...G.SG.....RWMLNLAKKMELRAIFTGYYGK.GKPV.P..T.QGS.RKGGAMQS-..CTI....................................................
#=GR A0A8C9DLL6_PROSS/54-288 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A7K4YWN5_BUCAB/184-420 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.S..K.....YF....aP.A.I.E..D.P.K....MK...V.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..E.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AS.Y.GKGFTLSISALFITTK.TVGARVELS.E.QQ..L...LLW..P.A.D...ADK.................................IL.PT.....D.....NL..P.K....GSRAHITLGCANGIEAVQTGLDLLEF.VKLE.K....A..G...N...K.....G.......D....EV...G...EI...G..G...G..K..L.....LYF...D.NR.....MWMLILSKKIDVRAIFSGYYGK.GKLV.P..T.QST.NKRGSAFSS..CTI....................................................
#=GR A0A7K4YWN5_BUCAB/184-420 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A7L1GWF1_9PICI/184-420 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.S..K.....YF....aS.A.I.E..D.P.K....IK...I.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYS..E.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.R.AS.Y.GKGFTLSISALFITTK.TVGARVELS.E.QQ..L...LLW..P.G.D...ADK.................................IL.PT.....D.....SL..P.K....GSRAHITLGCANGVEAVQTGFDLLEF.VKLE.K....A..G...N...K.....G.......E....QV...G...EI...G..G...G..K..L.....LYF...D.NG.....MWLLVLAKKLEVRAIFSGYYGK.GKLV.P..T.QST.NKRGSAFSS..CTI....................................................
#=GR A0A7L1GWF1_9PICI/184-420 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A4S2M816_OPIFE/320-442 ..................................tdvlrhwhsatlptfgvglk-----------.-.----.-.-.-.--.-.-..-.-.--..-....-.--.-----.-.-..-.....--.....-.-.-.-..-.-.-....--...-.-.....--....--.-....V..S.......R....A....A..S...V..PHITAKYA..R.F.G..R..A..AG...A...Q.....Q...YA.....L.....SGAV.T.ESlL.GRLFTVQVTGLFFSLR.TVGVRIRLP.A.DD..LvlrHLW..A.S.D...DQA.................................VL.ST.....D.....--..-.-....--------------------------.----.-....-..-...-...-.....-.......-....--...-...--...-..-...-..-..-.....---...-.--.....----------------------.----.-..-.---.---------..---rtefadfrwqrvsiccdceq................................
A0A3Q3L9L2_9LABR/760-993 ......................................................LPLFFGWFLLS.S.VQDK.I.R.C.TS.M.D..F.L.KT..L....D.TL.DAFKK.H.L..I.....DF.....-.-.T.G..K.A.E....KE...V.D.....LE....QY.F....-..-.......Q....A....K..G...T..LHCTTKFC..D.Y.G..K..A..EG...A...K.....D...YA.....E.....NQAV.N.DL.Y.GSVSELSLSALFVTPR.TVGARVSLT.E.EQ..L...VLW..P.A.D...AEKe..............................adVP.AA.....A.....SL..P.R....GSRAHITLGCSEGVEPVQTGVDLLEI.LALQ.Q....E..G...Q...Q.....G.......E....LV...E...EM...E..L...G..S..L.....TYY...G.SG.....RWLLSLREPICAPACFSSYYGR.KEAE.P..T.KKE.PERRRKPK-..CTI....................................................
#=GR A0A3Q3L9L2_9LABR/760-993 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A7J8CX61_MOLMO/164-396 ......................................................LPLYFGWFLTK.K.SSES.L.R.K.AG.Q.A..F.L.DE..L....G.NH.KAFKK.E.L..R.....HF.....I.S.G.D..E.P.R....EK...V.D.....LV....SY.F....G..K.......R....P....P..G...V..LHCTTKFC..D.Y.G..K..A..AG...A...E.....E...YA.....Q.....QDVV.K.KS.Y.SKAFTLTISALFVTPK.TAGAQVELS.E.QE..L...LLW..P.N.D...VDK.................................LS.PT.....D.....SL..P.R....GSRAHITLGCADDVEAVQTGIDLLEI.VQQ-.K....G..G...S...R.....-.......E....EV...G...EL...T..R...G..K..L.....FSL...G.SG.....RWMLNLTKKLKVRTIFTGYYGK.GKPV.P..T.HGS.RRGGAFQS-..CTI....................................................
#=GR A0A7J8CX61_MOLMO/164-396 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
M7BXE3_CHEMY/166-401 ......................................................LPLYYGWFLSK.K.SSEN.L.R.K.TG.Q.A..F.L.DE..L....G.SL.KVFKK.E.S..K.....YF.....L.P.A.E..D.P.K....VK...L.D.....LT....SY.F....A..K.......R....P....P..G...V..LHCTTKFT..D.F.G..K..A..MG...A...D.....E...YA.....Q.....QEVV.K.AS.Y.GKAFTLTISALFLTTK.TAGARVELS.E.QE..L...LLW..P.G.D...VDK.................................IL.PT.....D.....NL..P.K....GSRAHVTLGCASGIEPVQTGIDLLEF.VKLE.K....A..G...N...K.....G.......D....EI...E...EV...G..G...G..K..L.....QYF...G.NG.....MWMLLLSKKIEVKAIFSGYYGK.GKLV.P..T.QGS.NKRGSAFNP..CTI....................................................
#=GR M7BXE3_CHEMY/166-401 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A7K6EU53_9PASS/184-419 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.S..K.....YF.....P.S.V.E..D.P.K....IK...I.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..E.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AS.Y.GKGFTLSISALFITTK.TVGARIELS.E.QQ..L...LLW..P.G.D...ADK.................................IL.PT.....D.....NL..P.R....GSRAHITLGCANGVEAVQTGLDLLEF.VKLE.K....A..G...N...K.....G.......E....QV...G...EI...G..G...G..K..L.....LYF...D.NG.....MWMLVLSKKIDVRAIFSGYYGK.GKLV.P..T.QST.NKRGSAFSS..CTI....................................................
#=GR A0A7K6EU53_9PASS/184-419 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A8C5U7L8_9PASS/166-402 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.S..K.....YF....pS.A.I.E..D.P.K....IK...I.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..E.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AS.Y.GKGFTLSISALFITTK.TVGARIELS.E.QQ..L...LLW..P.G.D...ADK.................................IL.PT.....D.....NL..P.R....GSRAHITLGCANGVEAVQTGLDLLEF.VKLE.K....A..G...N...K.....G.......E....QV...G...EI...G..G...G..K..L.....LYF...D.NG.....MWMLVLSKKIDVRAIFSGYYGK.GKLV.P..T.QST.NKRGSAFSS..CTI....................................................
#=GR A0A8C5U7L8_9PASS/166-402 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
A0A814AZI9_9BILA/414-500 ...........................................stilhptcgfm-----------.-.----.-.-.-.--.-.-..-.-.--..-....-.--.-----.-.-..-.....--.....-.-.-.-..-.-.-....--...-.-.....--....--.-....-..-.......-....-....-..-...-..--------..-.-.-..-..-..--...-...-.....-...--.....-.....----.-.--.-.----------------.---------.-.--..-...---..-.-.-...---.................................--.--.....-.....--..-.-....-SRAHFTVGVAPGSSAVQTGQDLLSI.IQKE.S....D..L...Q...K.....S.......C....VAlcdN...KL...N..Q...T..V..M.....KYM...G.NG.....ECAVYLKEPILVQTIFSGA---.----.-..-.---.---------..---fh..................................................
A0A851E6W8_9CORV/184-420 ......................................................LPMYFGWFLSK.R.SSEI.L.R.K.AG.Q.A..F.L.DE..L....G.SL.KAFKK.E.S..K.....YF....pS.A.A.E..D.P.K....IK...T.D.....LT....SY.F....V..K.......R....P....P..G...V..LHCTTKYT..D.F.G..K..A..AG...A...E.....E...YA.....Q.....QEAV.K.AS.Y.GKGFTLSISALFITTK.TVGARIELS.E.QQ..L...LLW..P.G.D...ADK.................................IL.ST.....D.....NL..P.R....GSRAHITLGCANGVEAVQTGLDLLEF.VKLE.K....A..G...N...K.....G.......E....QV...G...EI...G..G...G..K..L.....LYF...D.NG.....MWMLVLSKKIDVRAIFSGYYGK.GKLV.P..T.QST.NKRGSAFSS..CTI....................................................
#=GR A0A851E6W8_9CORV/184-420 pAS ..............................................................................................................................................................................................................*......................................................................................................................................................................................*.....................................................................................................................................................................................................................
#=GC seq_cons ......................................................LPhYFGWFLoK.+.SSEh.L.R.K.sG.Q.s..F.L.-E..L....G.sh.KAFKK.E....+.....hF.......s.h.-..-.P.+.....K...l.D.....Ls....oY.F....s..K.......R....P....P..G...V..LHCTTKas..-.a.G..K..A..sG...A...-.....E...YA.....Q.....Q-sV.K.tS.Y.GKuFTLoISALFlTsK.TsGARV-LS.E.QQ..L...hLW..P.u.D...sDK.................................l..so.....D.....sL..P.+....GSRAHITLGCAsGVEAVQTGlDLLEh.V+hE.K....u..G...s...+.....G.......E....pV...G...El...s..t...G..K..L.....h.h...s.sG.....hWMLsLuKplcV+AIFoGYYGK.GK.V.P..T.pus.pKtGuh.s...CTI....................................................
//
