#=GF ID CRF-BP
#=GF AC PF05428.15
#=GF DE Corticotropin-releasing factor binding protein (CRF-BP)
#=GF AU Moxon SJ;0000-0003-4644-1816
#=GF SE Pfam-B_11928 (release 8.0)
#=GF GA 25.00 25.00;
#=GF TC 25.00 25.30;
#=GF NC 23.90 24.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF WK Corticotropin-releasing_hormone_binding_protein_family
#=GF RN [1]
#=GF RM 12379493
#=GF RT Corticotropin-releasing hormone-binding protein: biochemistry
#=GF RT and function from fishes to mammals.
#=GF RA Seasholtz AF, Valverde RA, Denver RJ;
#=GF RL J Endocrinol 2002;175:89-97.
#=GF DR INTERPRO; IPR008435;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family consists of several eukaryotic
#=GF CC corticotropin-releasing factor binding proteins (CRF-BP or
#=GF CC CRH-BP). Corticotropin-releasing hormone (CRH) plays multiple
#=GF CC roles in vertebrate species. In mammals, it is the major
#=GF CC hypothalamic releasing factor for pituitary adrenocorticotropin
#=GF CC secretion, and is a neurotransmitter or neuromodulator at other
#=GF CC sites in the central nervous system. In non-mammalian
#=GF CC vertebrates, CRH not only acts as a neurotransmitter and
#=GF CC hypophysiotropin, it also acts as a potent thyrotropin-releasing
#=GF CC factor, allowing CRH to regulate both the adrenal and thyroid
#=GF CC axes, especially in development. CRH-BP is thought to play an
#=GF CC inhibitory role in which it binds CRH and other CRH-like ligands
#=GF CC and prevents the activation of CRH receptors. There is however
#=GF CC evidence that CRH-BP may also exhibit diverse extra and
#=GF CC intracellular roles in a cell specific fashion and at specific
#=GF CC times in development [1].
#=GF SQ 947
#=GS A0A2K6GMQ1_PROCO/1-307 AC A0A2K6GMQ1.1
#=GS A0A665SZW8_ECHNA/1-308 AC A0A665SZW8.1
#=GS A0A8C7LGB5_ONCKI/1-285 AC A0A8C7LGB5.1
#=GS A0A7K5WH77_9SYLV/1-307 AC A0A7K5WH77.1
#=GS A0A6P7JB35_9TELE/1-306 AC A0A6P7JB35.1
#=GS A0A2K5LZT4_CERAT/1-286 AC A0A2K5LZT4.1
#=GS A0A7K5MN49_CARCD/1-307 AC A0A7K5MN49.1
#=GS A0A1A6HP76_NEOLE/18-128 AC A0A1A6HP76.1
#=GS A0A7K7VWU0_9AVES/1-307 AC A0A7K7VWU0.1
#=GS A0A8J4L7G5_EUDCH/1-307 AC A0A8J4L7G5.1
#=GS A0A7L2GVG6_NYCGR/1-307 AC A0A7L2GVG6.1
#=GS A0A8V0YI07_CHICK/10-316 AC A0A8V0YI07.1
#=GS A0A7L0NAG6_9PASS/1-307 AC A0A7L0NAG6.1
#=GS A0A2I0M179_COLLI/1-271 AC A0A2I0M179.1
#=GS D2HTE8_AILME/1-307 AC D2HTE8.1
#=GS A0A7L3MRZ2_9PASS/28-139 AC A0A7L3MRZ2.1
#=GS A0A3Q0H0K8_ALLSI/224-305 AC A0A3Q0H0K8.1
#=GS A0A0L0BL54_LUCCU/41-282 AC A0A0L0BL54.1
#=GS A0A6P8W3M0_GYMAC/1-308 AC A0A6P8W3M0.1
#=GS A0A7J5YIG3_DISMA/92-340 AC A0A7J5YIG3.1
#=GS A0A8C6VQD0_NAJNA/22-280 AC A0A8C6VQD0.1
#=GS A0A7K7RYY0_9PASS/1-307 AC A0A7K7RYY0.1
#=GS A0A671UCD6_SPAAU/1-308 AC A0A671UCD6.1
#=GS A0A5F8GDA1_MONDO/62-256 AC A0A5F8GDA1.1
#=GS A0A7K9D6F2_9AVES/1-307 AC A0A7K9D6F2.1
#=GS A0A5C6MZH6_9TELE/1-308 AC A0A5C6MZH6.1
#=GS Q7QI17_ANOGA/89-342 AC Q7QI17.5
#=GS A0A310SE12_9HYME/10-328 AC A0A310SE12.1
#=GS A0A7L3KPE3_9PASS/1-307 AC A0A7L3KPE3.1
#=GS A0A0J7KPC1_LASNI/1-108 AC A0A0J7KPC1.1
#=GS A0A803VHX0_FICAL/53-338 AC A0A803VHX0.1
#=GS A0A6G0ZF50_APHCR/9-286 AC A0A6G0ZF50.1
#=GS A0A1D1UIS7_RAMVA/4-306 AC A0A1D1UIS7.1
#=GS A0A5E4B9D5_MARMO/1-130 AC A0A5E4B9D5.1
#=GS D6W9E0_TRICA/3-327 AC D6W9E0.1
#=GS A0A8C6WEP8_9GOBI/1-309 AC A0A8C6WEP8.1
#=GS A0A315V8K4_GAMAF/197-504 AC A0A315V8K4.1
#=GS A0A834CCX7_ORYME/35-342 AC A0A834CCX7.1
#=GS A0A7K7LMI9_9AVES/1-307 AC A0A7K7LMI9.1
#=GS A0A226NFD3_CALSU/85-182 AC A0A226NFD3.1
#=GS A0A7K6A542_ONYCO/1-307 AC A0A7K6A542.1
#=GS A0A8B9UYZ8_9AVES/62-368 AC A0A8B9UYZ8.1
#=GS A0A4S2JD14_9HYME/1368-1665 AC A0A4S2JD14.1
#=GS A0A8C9IHH3_9PRIM/1-307 AC A0A8C9IHH3.1
#=GS A0A4W6DDU6_LATCA/4-309 AC A0A4W6DDU6.1
#=GS A0A3M0L0C2_HIRRU/1-110 AC A0A3M0L0C2.1
#=GS A0A8C5REQ2_LATLA/170-398 AC A0A8C5REQ2.1
#=GS A0A4Z2BAF7_9TELE/1-58 AC A0A4Z2BAF7.1
#=GS A0A1D1UFG1_RAMVA/48-235 AC A0A1D1UFG1.1
#=GS A0A8C7ZS77_9TELE/1-308 AC A0A8C7ZS77.1
#=GS A0A6J1UEI1_9SAUR/1-307 AC A0A6J1UEI1.1
#=GS A0A6P6LZH5_CARAU/1-307 AC A0A6P6LZH5.1
#=GS A0A2I0UEM3_LIMLA/80-265 AC A0A2I0UEM3.1
#=GS A0A1Y3AVL9_EURMA/18-184 AC A0A1Y3AVL9.1
#=GS A0A093G5Y8_DRYPU/1-307 AC A0A093G5Y8.1
#=GS A0A7K9VHF0_ANSSE/1-307 AC A0A7K9VHF0.1
#=GS A0A7L4HW17_SCOUM/1-307 AC A0A7L4HW17.1
#=GS A0A4C1YNJ1_EUMVA/211-396 AC A0A4C1YNJ1.1
#=GS A0A7L3P883_9DEND/1-307 AC A0A7L3P883.1
#=GS Q6DG79_DANRE/1-307 AC Q6DG79.1
#=GS S7ME82_MYOBR/1-307 AC S7ME82.1
#=GS A0A7L0UA21_CHOAC/1-307 AC A0A7L0UA21.1
#=GS A0A8J5DNK0_9DIPT/19-269 AC A0A8J5DNK0.1
#=GS H2UE09_TAKRU/1-308 AC H2UE09.3
#=GS A0A7K8GT82_ORTSP/1-307 AC A0A7K8GT82.1
#=GS A0A099YZP1_TINGU/1-307 AC A0A099YZP1.1
#=GS A0A2K6T4V2_SAIBB/1-307 AC A0A2K6T4V2.1
#=GS A0A8M1F445_URSMA/1-300 AC A0A8M1F445.1
#=GS A0A084VN19_ANOSI/170-464 AC A0A084VN19.1
#=GS B3MTC3_DROAN/100-343 AC B3MTC3.1
#=GS A0A7L3EZ12_9GRUI/1-307 AC A0A7L3EZ12.1
#=GS A0A2K5CJ25_AOTNA/1-307 AC A0A2K5CJ25.1
#=GS A0A7L1CQD8_9PASS/1-307 AC A0A7L1CQD8.1
#=GS A0A2Y9LP15_DELLE/1-307 AC A0A2Y9LP15.1
#=GS G1L4W4_AILME/21-300 AC G1L4W4.2
#=GS V3Z389_LOTGI/5-256 AC V3Z389.1
#=GS A0A7L3QGZ0_9SYLV/1-307 AC A0A7L3QGZ0.1
#=GS A0A3P9BR87_9CICH/1-308 AC A0A3P9BR87.1
#=GS A0A7K5GVH2_9AVES/1-307 AC A0A7K5GVH2.1
#=GS A0A6I8U476_AEDAE/31-313 AC A0A6I8U476.1
#=GS A0A2I4DCC4_9TELE/1-306 AC A0A2I4DCC4.1
#=GS A0A3Q1FUS9_9TELE/19-275 AC A0A3Q1FUS9.1
#=GS A0A7K7Z2N9_THRLU/1-307 AC A0A7K7Z2N9.1
#=GS A0A3Q3WFU9_MOLML/1-287 AC A0A3Q3WFU9.1
#=GS A0A087TAS1_STEMI/1-109 AC A0A087TAS1.1
#=GS A0A7L2ZGQ6_9PASE/1-307 AC A0A7L2ZGQ6.1
#=GS A0A8B7PM19_HYAAZ/4-195 AC A0A8B7PM19.1
#=GS A0A852DK15_PASAF/1-307 AC A0A852DK15.1
#=GS A0A226NFD3_CALSU/170-320 AC A0A226NFD3.1
#=GS A0A7K9PVC9_9CORV/1-307 AC A0A7K9PVC9.1
#=GS A0A4Z2BAF7_9TELE/99-178 AC A0A4Z2BAF7.1
#=GS A0A7R8GYM6_LEPSM/7-291 AC A0A7R8GYM6.1
#=GS A0A850V3N0_9CORV/1-307 AC A0A850V3N0.1
#=GS A0A835NGB5_9PASS/46-352 AC A0A835NGB5.1
#=GS A0A482XR26_LAOST/17-308 AC A0A482XR26.1
#=GS A0A7K4VJ85_9EMBE/1-307 AC A0A7K4VJ85.1
#=GS A0A8C5G4P7_9TELE/19-277 AC A0A8C5G4P7.1
#=GS A0A674IX33_TERCA/1-237 AC A0A674IX33.1
#=GS A0A8C9ZN14_SANLU/1-308 AC A0A8C9ZN14.1
#=GS A0A484CK82_PERFV/4-309 AC A0A484CK82.1
#=GS A0A6P3R920_PTEVA/1-307 AC A0A6P3R920.1
#=GS A0A7E5W9U4_TRINI/3-311 AC A0A7E5W9U4.1
#=GS A0A1W0XEC3_HYPDU/32-318 AC A0A1W0XEC3.1
#=GS A0A7J7XYE8_MYOMY/53-359 AC A0A7J7XYE8.1
#=GS U3I437_ANAPP/62-368 AC U3I437.2
#=GS A0A1L8I218_XENLA/1-306 AC A0A1L8I218.1
#=GS A0A2A3E1X7_APICC/9-326 AC A0A2A3E1X7.1
#=GS A0A8K1GCL0_9PASS/1-307 AC A0A8K1GCL0.1
#=GS A0A852NP37_9PASS/1-307 AC A0A852NP37.1
#=GS A0A8D2IS93_VARKO/1-303 AC A0A8D2IS93.1
#=GS A0A6G1B4I2_CROCR/1-307 AC A0A6G1B4I2.1
#=GS A0A6A1QB23_BALPH/1-307 AC A0A6A1QB23.1
#=GS A0A1S3FVW3_DIPOR/1-307 AC A0A1S3FVW3.1
#=GS A0A7L0DB53_9CHAR/1-307 AC A0A7L0DB53.1
#=GS A0A087X606_POEFO/1-310 AC A0A087X606.1
#=GS A0A7K9K4F0_9PASE/26-218 AC A0A7K9K4F0.1
#=GS B4K8R2_DROMO/86-336 AC B4K8R2.1
#=GS A0A3Q1HVG0_ANATE/4-309 AC A0A3Q1HVG0.1
#=GS A0A6L2PAF7_COPFO/1-214 AC A0A6L2PAF7.1
#=GS A0A0N8C7G5_9CRUS/20-328 AC A0A0N8C7G5.1
#=GS A0A6I9KH74_CHRAS/1-308 AC A0A6I9KH74.1
#=GS A0A7L0S943_GLABR/1-307 AC A0A7L0S943.1
#=GS A0A3Q1JAF8_ANATE/1-308 AC A0A3Q1JAF8.2
#=GS A0A7L4JPQ6_9AVES/1-307 AC A0A7L4JPQ6.1
#=GS A0A7L2RBT1_9PASS/1-307 AC A0A7L2RBT1.1
#=GS A0A7K9AGU1_9PASS/1-307 AC A0A7K9AGU1.1
#=GS A0A7K6MKL1_PANBI/1-307 AC A0A7K6MKL1.1
#=GS A0A7K7FCP9_CHIMN/1-307 AC A0A7K7FCP9.1
#=GS A0A8C2VF03_CHILA/1-307 AC A0A8C2VF03.1
#=GS A0A8B6ETQ8_MYTGA/1-254 AC A0A8B6ETQ8.1
#=GS A0A8B7RA67_HIPAR/1-307 AC A0A8B7RA67.1
#=GS A0A6P7FLI5_DIAVI/1-198 AC A0A6P7FLI5.1
#=GS A0A8C4Z9F8_GADMO/34-278 AC A0A8C4Z9F8.1
#=GS A0A091WL83_OPIHO/1-307 AC A0A091WL83.1
#=GS A0A1V4L0X5_PATFA/54-360 AC A0A1V4L0X5.1
#=GS A0A3Q3KXN0_9TELE/4-309 AC A0A3Q3KXN0.1
#=GS A0A091K4K8_COLST/1-307 AC A0A091K4K8.1
#=GS A0A6P6HVY3_PUMCO/1-69 AC A0A6P6HVY3.1
#=GS A0A7J7YVV3_PIPKU/1-239 AC A0A7J7YVV3.1
#=GS A0A6P6LZH2_CARAU/1-308 AC A0A6P6LZH2.1
#=GS A0A8C5AAB7_GADMO/34-210 AC A0A8C5AAB7.1
#=GS A0A851LDQ0_CORCR/1-307 AC A0A851LDQ0.1
#=GS A0A7K8EC44_LEURO/1-307 AC A0A7K8EC44.1
#=GS A0A8M1F7F5_URSMA/1-307 AC A0A8M1F7F5.1
#=GS A0A1S3HHR6_LINUN/27-299 AC A0A1S3HHR6.1
#=GS A0A1Y3B803_EURMA/1-151 AC A0A1Y3B803.1
#=GS A0A850TYA5_GRUAM/1-307 AC A0A850TYA5.1
#=GS A0A7K9S2K9_9PASS/1-299 AC A0A7K9S2K9.1
#=GS A0A2K6D7J6_MACNE/1-286 AC A0A2K6D7J6.1
#=GS M7B0S0_CHEMY/1-117 AC M7B0S0.1
#=GS A0A7L0GUV1_HERCA/1-307 AC A0A7L0GUV1.1
#=GS A0A7J8IYC5_MOLMO/87-348 AC A0A7J8IYC5.1
#=GS A0A3Q0GWW5_ALLSI/1-250 AC A0A3Q0GWW5.1
#=GS A0A8B7WDT8_CASCN/1-307 AC A0A8B7WDT8.1
#=GS A0A672HKP6_SALFA/4-309 AC A0A672HKP6.1
#=GS A0A3R7PFJ3_PENVA/5-149 AC A0A3R7PFJ3.1
#=GS A0A2P8Y3K7_BLAGE/1-154 AC A0A2P8Y3K7.1
#=GS A0A7L4N734_9AVES/1-307 AC A0A7L4N734.1
#=GS A0A6G1PZ42_9TELE/1-261 AC A0A6G1PZ42.1
#=GS A0A834F513_ORYME/122-426 AC A0A834F513.1
#=GS A0A7K8FCQ7_9CORV/1-307 AC A0A7K8FCQ7.1
#=GS A0A7K9LKJ1_9PASS/1-307 AC A0A7K9LKJ1.1
#=GS U4U0I0_DENPD/1-218 AC U4U0I0.1
#=GS G1KH88_ANOCA/82-390 AC G1KH88.2
#=GS A0A8C9BBF6_PHOSS/1-307 AC A0A8C9BBF6.1
#=GS A0A851UCA6_9PASS/1-307 AC A0A851UCA6.1
#=GS A0A2I4CRG6_9TELE/1-111 AC A0A2I4CRG6.1
#=GS A0A8C5Q0N7_9ANUR/1-306 AC A0A8C5Q0N7.1
#=GS A0A8C4BPW7_9TELE/29-335 AC A0A8C4BPW7.1
#=GS A0A667WWW1_9TELE/4-308 AC A0A667WWW1.1
#=GS A0A674CUQ9_SALTR/1-307 AC A0A674CUQ9.1
#=GS A0A7K9N8H7_9CORV/1-307 AC A0A7K9N8H7.1
#=GS A0A7K4S3T1_COLPI/1-307 AC A0A7K4S3T1.1
#=GS A0A3M0L0C2_HIRRU/108-148 AC A0A3M0L0C2.1
#=GS A0A8J6B235_GALPY/1-307 AC A0A8J6B235.1
#=GS A0A7K7QIX3_POEAT/1-307 AC A0A7K7QIX3.1
#=GS A0A6J2MVE5_9CHIR/1-306 AC A0A6J2MVE5.1
#=GS A0A2U9BUQ6_SCOMX/1-308 AC A0A2U9BUQ6.1
#=GS A0A668T268_OREAU/4-309 AC A0A668T268.1
#=GS A0A498M688_LABRO/91-375 AC A0A498M688.1
#=GS Q5F4H9_APIME/9-326 AC Q5F4H9.1
#=GS G3PT61_GASAC/4-307 AC G3PT61.1
#=GS A0A8C5RGA6_LATLA/170-455 AC A0A8C5RGA6.1
#=GS A0A2Y9JJ61_ENHLU/1-307 AC A0A2Y9JJ61.1
#=GS A0A7K4Q2V2_MELMO/1-307 AC A0A7K4Q2V2.1
#=GS A0A8C4KVS1_EQUAS/1-307 AC A0A8C4KVS1.1
#=GS E9H1T2_DAPPU/1-273 AC E9H1T2.1
#=GS A0A7L1QCR9_9PASS/1-307 AC A0A7L1QCR9.1
#=GS A0A6I9X1K2_9SAUR/1-307 AC A0A6I9X1K2.1
#=GS A0A6J3EK34_AYTFU/1-307 AC A0A6J3EK34.1
#=GS A0A672JRN9_SINGR/1-307 AC A0A672JRN9.1
#=GS W5MEP1_LEPOC/4-310 AC W5MEP1.1
#=GS A0A7K7UUW7_EUDEL/1-307 AC A0A7K7UUW7.1
#=GS A0A7L1ANJ6_GYMTI/1-307 AC A0A7L1ANJ6.1
#=GS A0A3S3PGC4_9ACAR/3-303 AC A0A3S3PGC4.1
#=GS A0A2T7PSC5_POMCA/1-87 AC A0A2T7PSC5.1
#=GS A0A0D9RS44_CHLSB/1-307 AC A0A0D9RS44.1
#=GS A0A2K6D7J0_MACNE/1-307 AC A0A2K6D7J0.1
#=GS A0A2R9C566_PANPA/1-307 AC A0A2R9C566.1
#=GS A0A8B7A104_ORYAF/1-307 AC A0A8B7A104.1
#=GS A0A8C5E0U6_9TELE/43-299 AC A0A8C5E0U6.1
#=GS A0A6J0BDT2_NEOLC/48-331 AC A0A6J0BDT2.1
#=GS A0A212FPC6_DANPL/4-232 AC A0A212FPC6.1
#=GS A0A7L0Q1H5_9AVES/1-307 AC A0A7L0Q1H5.1
#=GS A0A7K9MM77_OCETE/1-307 AC A0A7K9MM77.1
#=GS A0A212CUL5_CEREH/104-291 AC A0A212CUL5.1
#=GS A0A6L2P9G7_COPFO/2-150 AC A0A6L2P9G7.1
#=GS A0A1J1HR18_9DIPT/6-312 AC A0A1J1HR18.1
#=GS A0A5E4NCI0_9HEMI/1-308 AC A0A5E4NCI0.1
#=GS A0A8V0YB32_CHICK/94-350 AC A0A8V0YB32.1
#=GS A0A2Y9DHZ7_TRIMA/1-307 AC A0A2Y9DHZ7.1
#=GS A0A437CZ61_ORYJA/1-308 AC A0A437CZ61.1
#=GS A0A8K0D4M5_9COLE/18-220 AC A0A8K0D4M5.1
#=GS B4HZQ9_DROSE/98-345 AC B4HZQ9.1
#=GS A0A482X6E4_LAOST/1-89 AC A0A482X6E4.1
#=GS A0A6G0T8D8_APHGL/2-282 AC A0A6G0T8D8.1
#=GS A0A3P8WP57_CYNSE/1-237 AC A0A3P8WP57.1
#=GS A0A217FL62_MOUSE/1-314 AC A0A217FL62.1
#=GS A0A3Q2WHB6_HAPBU/4-309 AC A0A3Q2WHB6.1
#=GS A0A2U3WVC6_ODORO/1-307 AC A0A2U3WVC6.1
#=GS A0A6P3Y2D4_DINQU/1-324 AC A0A6P3Y2D4.1
#=GS A0A7K6PAF3_9CORV/1-307 AC A0A7K6PAF3.1
#=GS A0A7L3HJY2_9PASS/1-307 AC A0A7L3HJY2.1
#=GS A0A8C3GGA5_CAIMO/62-368 AC A0A8C3GGA5.1
#=GS A0A8C6VKQ1_NAJNA/19-281 AC A0A8C6VKQ1.1
#=GS CRHBP_MOUSE/1-307 AC Q60571.1
#=GS A0A7K5TAR5_9FRIN/1-307 AC A0A7K5TAR5.1
#=GS A0A226DMN5_FOLCA/101-255 AC A0A226DMN5.1
#=GS A0A7L4A1S2_9AVES/1-307 AC A0A7L4A1S2.1
#=GS A0A8D0HHM1_SPHPU/1-308 AC A0A8D0HHM1.1
#=GS A0A6P4FT27_DRORH/117-357 AC A0A6P4FT27.1
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A0A8C1IR26_CYPCA/1-307 .......................................................................................................MSGTSRVQLCFLL...LSVTALR.GHARFLg.iQ........................................DNEIS...PEGL.L..S........L.L..S..SEL..KREL.P......E...E...FV..YRRAL.......R.................C.LD.MVA.VEG.QFTF..T..A...E.....R.P...Q.L..N..CAVF.FIG.EPS.DIISIEYDSV..NI......DC....RG..G.............D......FI.......K.VFDGWVM.K.G...E.KF.PST...QDH.PL..P.L.YERYSD.Y.C.....ET.........G.................V......T.......R.P........IVR..S........SQNVAMLFFRLH.Q.SG..SS..FTV.TFR.....KLINPF..P...............CN..VV.....SQ..T.P....E....G....SFT...MII.P..Q.QH.RN.CSFS....I..........I..........YP..........V.....EIQ.IGELS..LGQH............ND.L...-.......-.............K...........R.......S.....I.......L.....G.....C..A...G..S..G..DFVELLG..G...N.GMDTSK.M...F.P.M.A...D..L.C..Y..S.F...N...GP...A...Q..M..K..V.G.CDNTVVRMVS..SG..KFV.NRVSFQYRLLGHQELQ................................
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A0A3Q0IQG4_DIACI/6-311 .................................................................hrfilvvlssflvccagsplgeffsrhqntptslqmpw-------------...-------.------...-........................................-----...----.-..-........-.-..Q..NNF..RQKK.A......S...E...QI..IV--E.......D.................C.ML.VTS.KEG.HFFY..K..S...K.....S.V...EpV..A..CGVF.LLT.DPD.KLVEVYFDYL..DV......PC....ET..G.............G......LV.......S.FVDGWEL.N.G...Q.FF.PSL...EDH.EK..P.L.HERFTE.F.C.....GT.........K.................R......I.......K.T........VFR..S........SQNAALIQYRVP.T.RG..KG..FSF.YVR.....YHKNPT..P...............CN..IL.....LE..G.L....S....D....VYT...LRN.Y..G.KS.VN.CSLT....T..........L..........YP..........A.....QVK.VLSLG..VGLS............NS.K...I.......K.............R...........Nqd...veV.....E.......T.....G.....T..L...H..K..A..DKRKFQY..R...I.GLGRGK.G...R.N.R.Y...V..L.L..-..-.D...T...NT...T...T..Y..S..I.L.CGVTTVRLVS..SG..EFD.NAVTVALTPA------qvedld..........................
B4R1M2_DROSI/93-345 ....................................................................................avagagagtaadvqelqpe-------------...-------.------...-........................................-----...----.-..-........-.-..-..---..----.-......-...-...--..-----.......-.................-.--.---.---.----..-..-...-.....-.-...-.-..V..CGLY.VIG.EPD.TIVEITMKHY..DA......NC....ET..G.............A......LM.......A.FVDGWEL.N.G...E.YF.PGI...KDH.HR..P.L.EERVYE.F.C.....NNyrq...wprV.................S......N.......K.K........FFR..S........SQNAALLQYRIP.V.RG..-S..FVA.NVR.....FHKITQ..P...............CN..VL.....VQ..D.T....A....A....MYT...MTN.F..G.QA.RN.CTIS....A..........L..........FP..........A.....VVS.LASLR..IGGK............SV.R...A.......Q.............P...........K.......V.....N.......Y.....D.....C..Q...L..P..S..DRLEIGG..S...A.GLDAIG.M...E.Q.A.S...A..V.C..G..A.S...S..dLG...P...E..Q..A..I.F.CGVSTVRLVS..SG..RYQ.NQAAIVLRKADVP---dme.............................
A0A3P9BGB4_9CICH/4-309 .......................................................................................................MERTFREQLFFLV...LCLSVLK.GDSRYI...E........................................NNEIT...KDEL.Y..S........F.F..N..SEL..KREM.P......E...E...LM..YRRPL.......R.................C.LD.MVA.VEG.QFTF..T..A...E.....R.P...Q.L..S..CAAF.FMA.EPN.EVISVDYDSV..DI......DC....TG..G.............D......FI.......T.VFDGWVM.K.G...E.KF.PST...HDH.PL..P.L.FERYVD.Y.C.....DS.........G.................S......L.......R.K........SVR..S........SQNVAMVFFRIH.S.AG..SS..FTL.TVR.....KHTNPF..P...............CN..VM.....SQ..S.P....E....G....SYT...MAI.P..Q.QH.RN.CSFS....I..........I..........YP..........V.....EIS.ISEFS..LGHY............NH.L...P.......-.............K...........R.......S.....M.......P.....G.....C..A...E..S..G..DFVQLLG..G...N.GIDTSK.L...L.P.I.T...D..L.C..I..A.F...T...GP...T...H..M..K..I.G.CDNTVVRMVS..SG..KFV.NRVSFSYRLLDSQELQ................................
A0A8C5Q0F3_9ANUR/8-312 .................................................................................skstiqchlhhqkfigrvsrtk-------------...-------.---AYC...Q........................................MKNAA...-EDA.L..F........L.I..N..SDL..KREL.S......E...E...QI..YRRSL.......R.................C.ID.MLS.IDG.QFTF..T..A...E.....R.P...Q.L..H..CALF.IIG.GPE.DFITIEYNFV..NI......NC....LG..G.............D......IL.......K.VFDGWII.K.G...E.KF.PSS...LDH.PL..S.T.VERYTD.I.C.....EL.........G.................K......M.......G.R........ITR..S........SQNVAMIFFRVQ.E.PG..NG..FTL.TIR.....KTPNLF..P...............CN..II.....SQ..S.P....S....G....QYT...MIV.P..H.QH.RN.CSFS....I..........I..........YP..........V.....VIK.IYDLT..LGHF............NE.L...Q.......L.............K...........K......pP.....P.......R.....G.....C..G...G..T..G..DFVELLG..G...T.GLDPSK.M...F.P.L.A...D..L.C..H..S.F...R...GS...A...Q..M..K..I.G.CDNSVIRMVS..SG..KFI.NQVTFEYNQLDRQ---ke..............................
A0A8C0LU53_CANLU/1-312 .......................................................................................................MSPSFKLKCHLVL...IFLMALR.GETRYL...Qvs...................................hlrLREAA...DRDP.L..L........L.W..G..ARL..KRDL.A......G...E...PE..YRRAL.......R.................C.LD.MLS.LPG.QFTF..T..A...D.....R.P...R.L..H..CAAF.LIA.EPE.ELITVHYDLV..SI......DC....RG..G.............D......FL.......K.VFDGWIL.K.G...E.KF.PSS...QDH.PL..P.T.TERYID.F.C.....DS.........G.................L......S.......R.R........SIR..S........SQNVAMIFFRVH.E.PG..NG..FTF.TIK.....TDPNLF..P...............CN..VI.....SQ..T.P....N....G....RFT...LVV.P..H.LH.RN.CSFS....I..........I..........YP..........A.....VIK.ISDLT..LGHL............SG.L...Q.......L.............K...........N.......P.....S.......A.....G.....C..G...G..I..G..DFVELLG..G...T.GLDPSK.M...M.P.L.A...D..L.C..Y..S.F...H...GP...A...Q..M..K..I.G.CDNTVVRLVS..SG..KHI.NRVTFEYRQLEPYELE................................
#=GC seq_cons .......................................................................................................M.sshphQhahlL...lhLsu.+.G-oRYl...E.........................................p-su...pc-..a...........L.h..u..tsL..KREL.u......t...t....l..YRRsL.......R.................C.lD.MLS.l-G.QFTF..T..A...-.....p.P...Q.L..p..CAsF.FIu.EP-.ElIoIcYDhV..sI......DC....pG..G.............D......FL.......K.VFDGWlL.K.G...E.KF.PSS....DH.PL..P.s.spRYlD.F.C.....-S.........G.................s......h.......p.R........olR..S........SQNVAMIFFRI+.p.PG..sG..FTl.TVK.....+ssNhF..P...............CN..VI.....SQ..T.P....s....G....pFT...MVl.P..H.QH.RN.CSFS....I..........I..........YP..........V.....sIK.ISDLh..LGHh............Ns.L...........l.............K...........+.......s.....s.......s.....G.....C..u...G..s..G..DFVELLG..G...s.GLDsSK.M...h.P.l.A...D..L.C..a..u.F...p...Gs...A...Q..M..K..I.G.CDNTVlRMVS..SG..+al.NRVTFpY+.L-.pEh.................................
//
