#=GF ID CSF-1
#=GF AC PF05337.15
#=GF DE Macrophage colony stimulating factor-1 (CSF-1)
#=GF AU Moxon SJ;0000-0003-4644-1816
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Pfam-B_7649 (release 7.7)
#=GF GA 25.00 25.00;
#=GF TC 25.00 25.00;
#=GF NC 24.90 24.80;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF CL CL0053
#=GF RN [1]
#=GF RM 11897698
#=GF RT Colony-stimulating factor 1 regulation of neuroendocrine
#=GF RT pathways that control gonadal function in mice.
#=GF RA Cohen PE, Zhu L, Nishimura K, Pollard JW;
#=GF RL Endocrinology 2002;143:1413-1422.
#=GF RN [2]
#=GF RM 12379742
#=GF RT The osteopetrotic mutation toothless (tl) is a loss-of-function
#=GF RT frameshift mutation in the rat Csf1 gene: Evidence of a crucial
#=GF RT role for CSF-1 in osteoclastogenesis and endochondral
#=GF RT ossification.
#=GF RA Van Wesenbeeck L, Odgren PR, MacKay CA, D'Angelo M, Safadi FF,
#=GF RA Popoff SN, Van Hul W, Marks SC Jr;
#=GF RL Proc Natl Acad Sci U S A 2002;99:14303-14308.
#=GF DR INTERPRO; IPR008001;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Colony stimulating factor 1 (CSF-1) is a homodimeric polypeptide
#=GF CC growth factor whose primary function is to regulate the
#=GF CC survival, proliferation, differentiation, and function of cells
#=GF CC of the mononuclear phagocytic lineage. This lineage includes
#=GF CC mononuclear phagocytic precursors, blood monocytes, tissue
#=GF CC macrophages, osteoclasts, and microglia of the brain, all of
#=GF CC which possess cell surface receptors for CSF-1. The protein has
#=GF CC also been linked with male fertility [1] and mutations in the
#=GF CC Csf-1 gene have been found to cause osteopetrosis and failure of
#=GF CC tooth eruption [2]. Structurally these are short-chain 4-helical
#=GF CC cytokines.
#=GF SQ 795
#=GS A0A3Q1HT09_ANATE/41-165 AC A0A3Q1HT09.2
#=GS A0A2U9C2K0_SCOMX/41-175 AC A0A2U9C2K0.1
#=GS A0A5N5L2K9_PANHP/36-178 AC A0A5N5L2K9.1
#=GS A0A2K6EXL5_PROCO/41-180 AC A0A2K6EXL5.1
#=GS A0A8L2QDI9_RAT/151-206 AC A0A8L2QDI9.1
#=GS A0A7K9RAX0_9PASS/1-131 AC A0A7K9RAX0.1
#=GS A0A852DXX6_VIDMA/1-131 AC A0A852DXX6.1
#=GS A0A670J1Q2_PODMU/29-168 AC A0A670J1Q2.1
#=GS A0A7L0ENY6_TROML/1-132 AC A0A7L0ENY6.1
#=GS A0A7K8BG03_9CORV/1-131 AC A0A7K8BG03.1
#=GS A0A2R9CE62_PANPA/28-167 AC A0A2R9CE62.1
#=GS A0A7K5FM87_PROAR/1-131 AC A0A7K5FM87.1
#=GS A0A803W2G8_FICAL/99-243 AC A0A803W2G8.1
#=GS A0A8C6QLJ6_NANGA/41-180 AC A0A8C6QLJ6.1
#=GS A0A7L0BJV0_9AVES/1-130 AC A0A7L0BJV0.1
#=GS A0A2I3LVH4_PAPAN/41-180 AC A0A2I3LVH4.2
#=GS A0A2K6L285_RHIBE/41-180 AC A0A2K6L285.1
#=GS A0A663FGB0_AQUCH/38-181 AC A0A663FGB0.1
#=GS A0A6P8THN5_GYMAC/39-156 AC A0A6P8THN5.1
#=GS A0A7K6P5Z5_9CORV/1-131 AC A0A7K6P5Z5.1
#=GS A0A7J8BDB4_ROUAE/41-180 AC A0A7J8BDB4.1
#=GS A0A672TDC5_SINGR/50-189 AC A0A672TDC5.1
#=GS A0A8C6X306_NAJNA/29-164 AC A0A8C6X306.1
#=GS A0A151N8J7_ALLMI/34-179 AC A0A151N8J7.1
#=GS A0A7K5D1H8_9TYRA/1-110 AC A0A7K5D1H8.1
#=GS A0A663LPQ4_ATHCN/1-126 AC A0A663LPQ4.1
#=GS H2M3Z7_ORYLA/86-212 AC H2M3Z7.2
#=GS A0A8B7PU54_HIPAR/41-179 AC A0A8B7PU54.1
#=GS A0A6J3E7G2_AYTFU/38-182 AC A0A6J3E7G2.1
#=GS A0A7K7LK07_9AVES/1-131 AC A0A7K7LK07.1
#=GS A0A7N4Q1H4_SARHA/40-181 AC A0A7N4Q1H4.1
#=GS A0A665SYF5_ECHNA/33-154 AC A0A665SYF5.1
#=GS A0A7K5IKN1_TOXRE/1-131 AC A0A7K5IKN1.1
#=GS A0A7L1MI24_BOMGA/1-131 AC A0A7L1MI24.1
#=GS A0A7K4YQV2_BUCAB/1-130 AC A0A7K4YQV2.1
#=GS A0A7K9WF54_9PASS/1-130 AC A0A7K9WF54.1
#=GS R0LG99_ANAPL/184-328 AC R0LG99.1
#=GS A0A8D0DZK2_SALMN/29-168 AC A0A8D0DZK2.1
#=GS A0A1S3P6J0_SALSA/36-178 AC A0A1S3P6J0.1
#=GS A0A8C6CU54_MOSMO/41-180 AC A0A8C6CU54.1
#=GS A0A7F8RWR8_LEPWE/41-180 AC A0A7F8RWR8.1
#=GS A0A1A6GXZ5_NEOLE/41-180 AC A0A1A6GXZ5.1
#=GS A0A7J5ZHY6_DISMA/22-130 AC A0A7J5ZHY6.1
#=GS A0A287BPE2_PIG/41-180 AC A0A287BPE2.3
#=GS A0A6P7IC85_9TELE/18-155 AC A0A6P7IC85.1
#=GS A0A850VYR8_FREMA/1-131 AC A0A850VYR8.1
#=GS A0A3Q3X964_MOLML/41-180 AC A0A3Q3X964.1
#=GS A0A850YNV7_AEGCA/1-131 AC A0A850YNV7.1
#=GS A0A4D9DXX8_9SAUR/62-206 AC A0A4D9DXX8.1
#=GS A0A8B7PTI0_HIPAR/41-179 AC A0A8B7PTI0.1
#=GS A0A7K8K0Y7_9GRUI/1-110 AC A0A7K8K0Y7.1
#=GS A0A8C8HU42_ONCTS/37-179 AC A0A8C8HU42.1
#=GS A0A7K9YA48_9GALL/1-96 AC A0A7K9YA48.1
#=GS D3YTW1_MOUSE/6-86 AC D3YTW1.1
#=GS A0A7L3BWN8_PELUR/1-130 AC A0A7L3BWN8.1
#=GS A0A7N4Q087_SARHA/40-181 AC A0A7N4Q087.1
#=GS A0A7L0V6F8_9PASE/1-110 AC A0A7L0V6F8.1
#=GS A0A7L0UPC2_CHOAC/1-131 AC A0A7L0UPC2.1
#=GS A0A2K5Z9R4_MANLE/28-167 AC A0A2K5Z9R4.1
#=GS A0A7K9QL50_IRECY/1-131 AC A0A7K9QL50.1
#=GS A0A803YAD2_MELGA/75-190 AC A0A803YAD2.1
#=GS A0A673VV83_SURSU/35-174 AC A0A673VV83.1
#=GS A0A667H6C9_LYNCA/41-180 AC A0A667H6C9.1
#=GS A0A5C6MR53_9TELE/41-180 AC A0A5C6MR53.1
#=GS A0A8B9NHA2_9AVES/38-181 AC A0A8B9NHA2.1
#=GS A0A1S3MCW1_SALSA/38-177 AC A0A1S3MCW1.1
#=GS A0A665T755_ECHNA/18-141 AC A0A665T755.1
#=GS A0A8B7FFL4_MICMU/41-180 AC A0A8B7FFL4.1
#=GS A0A8C0Y8Y0_CYPCA/4-139 AC A0A8C0Y8Y0.1
#=GS A0A4V5P9C5_MONMO/61-200 AC A0A4V5P9C5.1
#=GS A0A8V1AD32_CHICK/41-185 AC A0A8V1AD32.1
#=GS K7FQV9_PELSI/100-244 AC K7FQV9.1
#=GS A0A2K6U985_SAIBB/41-180 AC A0A2K6U985.1
#=GS U3JK10_FICAL/99-243 AC U3JK10.2
#=GS A0A7K9AX18_DRONO/1-131 AC A0A7K9AX18.1
#=GS A0A6P3FG06_OCTDE/41-180 AC A0A6P3FG06.1
#=GS A0A8C7BZ20_NEOVI/41-180 AC A0A8C7BZ20.1
#=GS A0A8C7D3S9_ONCKI/38-177 AC A0A8C7D3S9.1
#=GS A0A7L2AN00_9GRUI/1-131 AC A0A7L2AN00.1
#=GS A0A7L0W248_ALELA/1-131 AC A0A7L0W248.1
#=GS A0A851NUK1_9GALL/1-131 AC A0A851NUK1.1
#=GS A0A5F5PIK6_HORSE/41-180 AC A0A5F5PIK6.1
#=GS A0A668VLC4_OREAU/41-181 AC A0A668VLC4.1
#=GS A0A7J7SQ74_MYOMY/40-180 AC A0A7J7SQ74.1
#=GS A0A7K6S4N6_9GRUI/1-130 AC A0A7K6S4N6.1
#=GS A0A667H6D7_LYNCA/41-180 AC A0A667H6D7.1
#=GS A0A2K5I7R9_COLAP/35-174 AC A0A2K5I7R9.1
#=GS A0A669EGJ1_ORENI/41-181 AC A0A669EGJ1.1
#=GS A0A212CFF9_CEREH/36-175 AC A0A212CFF9.1
#=GS A0A3B1J390_ASTMX/34-176 AC A0A3B1J390.1
#=GS A0A553QJC7_9TELE/41-183 AC A0A553QJC7.1
#=GS A0A6J0DKM3_PERMB/19-84 AC A0A6J0DKM3.1
#=GS CSF1_MOUSE/41-180 AC P07141.2
#=GS A0A6P6QDD6_CARAU/36-177 AC A0A6P6QDD6.1
#=GS A0A7K6TQS9_9AVES/1-130 AC A0A7K6TQS9.1
#=GS A0A493TYR1_ANAPP/38-182 AC A0A493TYR1.1
#=GS A0A6P7IQY5_9TELE/41-178 AC A0A6P7IQY5.1
#=GS E9PKP4_HUMAN/1-113 AC E9PKP4.1
#=GS A0A7J6CR67_9TELE/38-178 AC A0A7J6CR67.1
#=GS A0A2K5I7S4_COLAP/51-190 AC A0A2K5I7S4.1
#=GS A0A7E6CYA2_9CHIR/35-171 AC A0A7E6CYA2.1
#=GS A0A851YKX4_9AVES/1-130 AC A0A851YKX4.1
#=GS I3N713_ICTTR/1-122 AC I3N713.2
#=GS A0A6J3RUD9_TURTR/41-180 AC A0A6J3RUD9.1
#=GS A0A7L1AS02_GYMTI/1-131 AC A0A7L1AS02.1
#=GS A0A8C4ZG33_GADMO/25-167 AC A0A8C4ZG33.1
#=GS A0A4W2FV08_BOBOX/41-180 AC A0A4W2FV08.1
#=GS A0A452GAN4_CAPHI/52-159 AC A0A452GAN4.1
#=GS A0A4W2D778_BOBOX/41-180 AC A0A4W2D778.1
#=GS A0A7K7S9J0_9PASS/1-131 AC A0A7K7S9J0.1
#=GS A0A8C9ENS5_PAVCR/67-211 AC A0A8C9ENS5.1
#=GS A0A1V4KXG4_PATFA/37-179 AC A0A1V4KXG4.1
#=GS A0A7K9MJH7_OCETE/1-131 AC A0A7K9MJH7.1
#=GS A0A851N1V9_9DEND/1-131 AC A0A851N1V9.1
#=GS A0A6I8PHF9_ORNAN/93-228 AC A0A6I8PHF9.1
#=GS A0A7L2YMF7_JACJC/1-130 AC A0A7L2YMF7.1
#=GS A0A673ABV5_9TELE/67-207 AC A0A673ABV5.1
#=GS A0A674GSJ5_TAEGU/41-185 AC A0A674GSJ5.1
#=GS A0A8C6TS43_9GOBI/84-222 AC A0A8C6TS43.1
#=GS F6RNW8_MOUSE/13-68 AC F6RNW8.8
#=GS A0A337SMK6_FELCA/41-180 AC A0A337SMK6.2
#=GS G3VNH3_SARHA/8-141 AC G3VNH3.2
#=GS M1H4U2_XENLA/43-185 AC M1H4U2.1
#=GS A0A6P6IRF8_PUMCO/41-180 AC A0A6P6IRF8.1
#=GS A0A3P8X0Q9_CYNSE/41-177 AC A0A3P8X0Q9.1
#=GS A0A6J2KUI4_9CHIR/35-172 AC A0A6J2KUI4.1
#=GS A9JRD6_DANRE/36-177 AC A9JRD6.1
#=GS A0A8C0Y722_CYPCA/34-175 AC A0A8C0Y722.1
#=GS A0A455B866_PHYMC/62-201 AC A0A455B866.1
#=GS A0A7J8CQ48_MOLMO/41-180 AC A0A7J8CQ48.1
#=GS A0A673YQA2_SALTR/36-178 AC A0A673YQA2.1
#=GS A0A6J2J2E3_9PASS/38-182 AC A0A6J2J2E3.1
#=GS A0A8C0AZT3_9AVES/13-150 AC A0A8C0AZT3.1
#=GS A0A2K6CXU2_MACNE/41-180 AC A0A2K6CXU2.1
#=GS A0A5E4BGF0_MARMO/41-180 AC A0A5E4BGF0.1
#=GS A0A8N5I267_GEOFO/56-199 AC A0A8N5I267.1
#=GS A0A8D0G1V8_STROC/79-222 AC A0A8D0G1V8.1
#=GS A0A2R9CE96_PANPA/28-167 AC A0A2R9CE96.1
#=GS A0A6P6CVY4_PTEVA/118-257 AC A0A6P6CVY4.1
#=GS A0A3B1J9J3_ASTMX/8-143 AC A0A3B1J9J3.1
#=GS A0A2K5I7W5_COLAP/35-174 AC A0A2K5I7W5.1
#=GS A0A8U8B8H6_GEOPR/37-180 AC A0A8U8B8H6.1
#=GS A0A6I9NVZ0_9TELE/39-157 AC A0A6I9NVZ0.1
#=GS A0A7K7DUM2_9SYLV/1-131 AC A0A7K7DUM2.1
#=GS A0A8C5H550_9TELE/41-183 AC A0A8C5H550.1
#=GS G5BD69_HETGA/1-139 AC G5BD69.1
#=GS A0A8C9E551_PHOSS/41-180 AC A0A8C9E551.1
#=GS A0A7L2PTA1_9PASS/1-131 AC A0A7L2PTA1.1
#=GS A0A7K4VTI5_9EMBE/1-130 AC A0A7K4VTI5.1
#=GS A1A5Z5_DANRE/9-148 AC A1A5Z5.1
#=GS A0A2K6L284_RHIBE/73-212 AC A0A2K6L284.1
#=GS A0A7K8ZHZ1_9PASS/1-131 AC A0A7K8ZHZ1.1
#=GS A0A643C1Q3_BALPH/28-167 AC A0A643C1Q3.1
#=GS A0A7K6DFY2_9PASS/1-131 AC A0A7K6DFY2.1
#=GS A0A6P6ISR8_PUMCO/41-180 AC A0A6P6ISR8.1
#=GS A0A7K5A8W0_9AVES/1-130 AC A0A7K5A8W0.1
#=GS A0A4W4GEP6_ELEEL/38-180 AC A0A4W4GEP6.1
#=GS A0A7K8XJ79_9PICI/1-131 AC A0A7K8XJ79.1
#=GS A0A7L3B662_9AVES/1-129 AC A0A7L3B662.1
#=GS A0A852PDL2_9PASS/1-131 AC A0A852PDL2.1
#=GS A0A8C7C218_NEOVI/41-180 AC A0A8C7C218.1
#=GS A0A7L3W2M6_9GRUI/1-131 AC A0A7L3W2M6.1
#=GS A0A8D2MEY8_ZONAL/37-180 AC A0A8D2MEY8.1
#=GS A0A498LE64_LABRO/1-136 AC A0A498LE64.1
#=GS A0A7K8E3K6_LEURO/1-131 AC A0A7K8E3K6.1
#=GS A0A7K5I9K8_CROSL/1-131 AC A0A7K5I9K8.1
#=GS A0A7J6CP08_9TELE/36-177 AC A0A7J6CP08.1
#=GS A0A6P5BNK4_BOSIN/41-180 AC A0A6P5BNK4.1
#=GS A0A672SQX7_SINGR/36-177 AC A0A672SQX7.1
#=GS A0A673YAI5_SALTR/38-177 AC A0A673YAI5.1
#=GS A0A4Z2B5Q0_9TELE/41-181 AC A0A4Z2B5Q0.1
#=GS A0A1L8H6Z5_XENLA/43-185 AC A0A1L8H6Z5.1
#=GS A0A4W4DZ84_ELEEL/40-180 AC A0A4W4DZ84.1
#=GS A0A7K5R5Z8_9PASE/1-131 AC A0A7K5R5Z8.1
#=GS A0A852FLI8_PEUTA/1-131 AC A0A852FLI8.1
#=GS A0A7K7DM22_PHEME/1-131 AC A0A7K7DM22.1
#=GS A0A4W4DXK8_ELEEL/47-188 AC A0A4W4DXK8.1
#=GS A0A7N5JH13_AILME/1-139 AC A0A7N5JH13.1
#=GS A0A3Q3MA29_9TELE/41-182 AC A0A3Q3MA29.1
#=GS A0A7J8BDV1_ROUAE/41-180 AC A0A7J8BDV1.1
#=GS A0A0Q3P3W3_AMAAE/33-177 AC A0A0Q3P3W3.1
#=GS A0A3Q2E240_CYPVA/41-183 AC A0A3Q2E240.1
#=GS A0A674BR04_SALTR/62-200 AC A0A674BR04.1
#=GS A0A851JJ42_9PASS/1-131 AC A0A851JJ42.1
#=GS A0A7K5B688_9FURN/1-131 AC A0A7K5B688.1
#=GS A0A2K5BUK7_AOTNA/41-180 AC A0A2K5BUK7.1
#=GS A0A8C3KJ23_9CHAR/27-169 AC A0A8C3KJ23.1
#=GS A0A7L1TFM0_ARAGA/1-131 AC A0A7L1TFM0.1
#=GS A0A7L4N6N6_9AVES/1-131 AC A0A7L4N6N6.1
#=GS A0A5F8AAN1_MACMU/1-139 AC A0A5F8AAN1.1
#=GS A0A673VUN3_SURSU/35-174 AC A0A673VUN3.1
#=GS A0A7K8FX60_9CORV/1-131 AC A0A7K8FX60.1
#=GS A0A7L2X962_9PASS/1-131 AC A0A7L2X962.1
#=GS A0A671NTY6_9TELE/34-134 AC A0A671NTY6.1
#=GS A0A1U8DKZ4_ALLSI/1-128 AC A0A1U8DKZ4.2
#=GS H7BY18_HUMAN/41-119 AC H7BY18.1
#=GS G1U8S7_RABIT/35-174 AC G1U8S7.2
#=GS A0A2K5Z9R2_MANLE/28-167 AC A0A2K5Z9R2.1
#=GS W5N2I6_LEPOC/41-183 AC W5N2I6.1
#=GS A0A8C5JTQ2_JUNHY/38-181 AC A0A8C5JTQ2.1
#=GS A0A3Q7SAY0_VULVU/34-173 AC A0A3Q7SAY0.1
#=GS A0A4W5JKB5_9TELE/38-177 AC A0A4W5JKB5.1
#=GS A0A8C6A1I7_MARMA/41-180 AC A0A8C6A1I7.1
#=GS A0A2U9BZU5_SCOMX/41-175 AC A0A2U9BZU5.1
#=GS A0A2Y9QP26_TRIMA/11-118 AC A0A2Y9QP26.1
#=GS A0A7L4G4I9_9COLU/1-131 AC A0A7L4G4I9.1
#=GS A0A6I9YL49_9SAUR/29-164 AC A0A6I9YL49.1
#=GS A0A7L2LCW9_9SYLV/1-130 AC A0A7L2LCW9.1
#=GS A0A852AEQ0_9CORV/1-131 AC A0A852AEQ0.1
#=GS I3KL12_ORENI/41-181 AC I3KL12.1
#=GS A0A8C4YLL9_9SAUR/37-181 AC A0A8C4YLL9.1
#=GS A0A1S3A4X1_ERIEU/41-180 AC A0A1S3A4X1.1
#=GS A0A673HEJ1_9TELE/38-178 AC A0A673HEJ1.1
#=GS A0A811Z3Q8_NYCPR/41-180 AC A0A811Z3Q8.1
#=GS A0A2Y9J3N5_ENHLU/41-180 AC A0A2Y9J3N5.1
#=GS A0A7K4X1C3_9TYRA/1-131 AC A0A7K4X1C3.1
#=GS F1MGS9_BOVIN/41-180 AC F1MGS9.1
#=GS A0A7K9SRS0_9AVES/1-131 AC A0A7K9SRS0.1
#=GS A0A7L2GP83_NYCGR/1-131 AC A0A7L2GP83.1
#=GS A0A8C9CBJ0_PHOSS/41-180 AC A0A8C9CBJ0.1
#=GS A0A7K5X4N7_9CHAR/1-131 AC A0A7K5X4N7.1
#=GS A0A8C0Y876_CYPCA/34-175 AC A0A8C0Y876.1
#=GS A0A7L1BRZ7_9PASS/1-131 AC A0A7L1BRZ7.1
#=GS A0A2I2YQ72_GORGO/47-186 AC A0A2I2YQ72.1
#=GS A0A7K4XUY8_REGSA/1-131 AC A0A7K4XUY8.1
#=GS A0A8I6AN73_RAT/55-194 AC A0A8I6AN73.1
#=GS A0A3Q7P3A5_CALUR/41-180 AC A0A3Q7P3A5.1
#=GS A0A8B9DZ69_ANSCY/183-327 AC A0A8B9DZ69.1
#=GS A0A2K6U977_SAIBB/41-180 AC A0A2K6U977.1
#=GS A0A2K5TMB7_MACFA/41-180 AC A0A2K5TMB7.2
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A0A1A7ZCX0_NOTFU/41-181 ..............................HSITREHLLTVRQL............MDNQL.RSGCSITYTFIERRM...L....S.-KCCFVKAALPWILELLTTHFKYKRGSINDGYVQ...SL....R....A....L....I.L....N....I....Y....Sq..rC...V....P...QineE..I..E....D...K....P....E...S...FE...I...V..Y...HGS.PLNALQKASDVLSVY-------------------.-----welvttrdspvdwrcqheyse....................................
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A0A7K7U7G0_9CHAR/1-110 ..............................--------------............-----.---------------...-....N.DSVCYVKAAFPLLGKILERT-EFKENSSNAKKMQ...MV....R....R....MysriD.E....N....V....D....P....C...I....R...E...E..D..D....E...E....R....KlsqM...CF...E...E..F...TTS.PYEMLVLVKQFFQDINQLLQN-QETFEKDCSQVY.R----rtcl.....................................................
A0A7L4JE97_9PASS/1-127 ...........................mqh--------------............-----.--PGRVSFKFIDKMQ...L....N.DSVCYVKAAFPLMGKILERT-EFKENSSNARKMQ...TV....R....R....M....Y.D....R....IdesvD....P....C...I....R...E...E..D..D....E...Er.tlS....Q...M...CF...K...E..F...TTS.PYEMLVLVKDFFQDIKRLLQN-QETFEKDCSRVY.R----racp.....................................................
A0A7K9F2F3_STEPR/1-110 ..............................--------------............-----.---------------...-....N.DSVCYVKAAFPLLGKILERT-EFKENSSNAKKMQ...MV....R....K....MysriD.E....N....I....D....P....C...I....R...E...E..D..D....E...E....R....KlsqM...CF...E...E..F...TTS.PYEMLVLVKQFFQDINQLLQ-NRETFEKDCSQVY.R----rtcl.....................................................
A0A7K6EBX2_9PASS/1-130 .............................a--------------............-DTQM.QHPGRVSFKFIDKTQ...L....N.DSICYVKAAFPLLGKILERT-EFKENSSNARKMQ...MV....R....R....M....Y.N....RidenV....D....P....C...I....R...E...E..D..D....E...Er.mlS....Q...M...CF...K...E..F...TTS.PYEMLVLVKDFFQDINHLLQN-QETFEKDCSRVY.-----rrac.....................................................
A0A8L2QDI9_RAT/40-147 ..............................HMIGNGHLQILQQL............IDSQM.ETACLIEYKFVDQEQ...L....D.DPVCYLKKAFVLVQVIIEETMRFKDNTPNANATE...RL....Q....E....L....S.M....K....L....N....S....C...F....I...K...D..Y..K....E...Q....N....E...H...SL...-...-..-...---.----------------------------------.-----drrhsvdpedilg............................................
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A0A7L0TGS7_PODPO/1-130 .............................a--------------............-DTQM.QQPGRVSFKFIDKMR...L....N.DSVCYVKAAFPLLGKILEQT-KFKENSSNAKKMQ...MV....R....K....MysriD.E....N....V....D....P....C...I....R...E...E..E..E....E...Er.elS....Q...M...CF...E...E..F...TTS.PYKMLVLVKQFFQDINQLLQN-QETFEKDCSQVY.R----rtc......................................................
A0A8C4RP86_ERPCA/39-176 ..........................nsmk----QEHLSILDRL............VANQL.VNSCNIRYKFIEESQ...L....S.K-TCFVKAVFPKILDLLNDHFKYGKNSSNGKDVQ...LL....K....D....L....I.G....N....I....Y....Ki..rC...Ip.piD...L...D..K..E....D...N....P....E...K...FW...K...D..F...DEP.PQAALRRIRSAAAIYLNLL---------------.-----atyrkgpnwecsey...........................................
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A0A7F8RWU1_LEPWE/41-180 ..............................HMIGNGHLQFLQQL............IDSQM.ETSCQIAFEFVDQEQ...L....K.DPVCYLKKAFPLVQDIMEDTMRFKDNTPNANVIV...KL....Q....E....L....S.L....R....L....K....S....C...F....T...K...D..Y..E....E...Q....D....K...A...CV...R...T..F...YET.PLQLLEKIKNVFNETKNLLKKDWNVFSKNCNNSF.AKCSS.........................................................
A0A6J3RUH4_TURTR/41-180 ..............................HMIGNGHLQVLQKL............IDSQM.ETSCQIAFEFVDQEQ...L....N.DPVCYLKKAFLLVQDIMEDTMRFRDNTPNAAVIV...QL....Q....E....L....S.L....R....L....R....S....C...F....T...R...D..Y..E....G...Q....D....K...A...CV...R...T..F...YET.PLQLLEKIKNVFNETKNLLKKNWNIFSKNCNNSF.AKCSS.........................................................
A0A4W5JKC5_9TELE/63-202 ..............................HSITRDHLLTIRHL............IDNQL.QSGCSITYTFIEQRS...L....N.K-CCYVKAAMPWILELLTGHFRYTRGSDNHSYVL...SL....T....G....L....I.H....N....I....Y....Sq..rC...V....P...Q...I..N..E....E...L....E....D...D...PVsfgM...S..F...SSS.PSEALGRVQDVLS---------------------.-----vywelvttmdspvdwscereyt...................................
A0A852CKY4_9PICI/1-131 .............................a--------------............-DTQM.QHPGRVSFKFINKMQ...L....N.DSVCYVKAAFPLLGKILERT-EFKENSTNAKRLQ...AV....R....RmyyrI....D.E....N....V....D....P....C...I....R...E...E..D..D....E...E....R....KlsqM...CF...K...E..F...TTS.PYEMLLLVKEFFQDINQLLQN-QETFERNCSQVY.-----fstcl....................................................
A0A8C4XNW7_FALTI/23-143 ..................sqfwgggsvslq--------------............-----.---------------...-....N.NSVCYVKAAFPLLGKILERT-EFKENSSNAKKMQ...MV....R....R....MysriD.E....N....V....D....P....C...I....R...E...E..D..D....E...E....R....KlsqM...CF...E...E..F...TTS.PYEMLVLVKQFFQDINQLLQN-KETFEKDCSQVY.R----rtc......................................................
A0A8C5S7P6_LATLA/29-164 .............................r-LIMASHLKNLTDL............IDSQM.ETSCLRSFEYVDERE...L....D.NTECFLKAAFNPLKGIIDN-IKFKNNSPNYVKLH...LI....K....N....L....Y.L....D....L....A....R....C...I....-...K...P..H..D....D...K....N....K...K...CI...K...T..F...SRT.AEQTLQLVHKYFSQAKQFLSKG--TFTDDCSGVF.QKCT-e........................................................
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A0A850YVI4_9PASS/1-131 .............................a--------------............-DTQM.QHPGRVSFKFIDKMQ...L....N.DSICYVKAAFPLMGKILERTV-FKENSSNARKMQ...TV....R....R....M....Y.N....RidenV....D....P....C...I....R...E...E..D..D....E...Er.mlS....Q...M...CF...K...E..F...TTS.PYEMLVLVKDFFQDIKRLLQN-QETFEKDCSRVY.R----racp.....................................................
A0A6J1ZBT4_ACIJB/41-180 ..............................HMIGNGHLQFLQQL............IDSQM.ETSCQIAFEFVDQEQ...L....K.DPVCYLKKAFLLVQDIMEDTMRFKDNTPNANVIV...TL....Q....E....L....S.L....R....L....S....S....C...F....T...K...D..Y..E....E...Q....D....K...A...CV...R...T..F...HET.PLQLLEKIKNVFNETKNLLKKDWNVFSKNCNKSF.EKCSS.........................................................
A0A8J4KJ12_EUDCH/1-131 .............................a--------------............-DTQM.QHPGRVSFKFINKMQ...L....N.DSVCYVKAAFPLLGKILERT-EFKENSSNAKKMQ...MV....R....S....MysriD.E....N....V....D....P....C...I....R...E...E..D..D....E...E....R....KlsqM...CF...E...E..F...TTS.PYEMLVLVKQFFQDINQLLQN-QETFEKDCSQVY.G----rtcl.....................................................
A0A8C0K9Z8_CANLU/41-180 ..............................HMIGNGHLQFLQQL............IDSQM.ETSCQIAFEFVDQEL...L....K.DPVCYLKKAFVLMQDIMEDTMRFKDNTPNANVIV...KL....Q....E....L....S.L....R....L....K....S....C...F....T...K...D..Y..E....E...Q....D....K...A...CV...R...T..F...YET.PLQLLEKIKNVFNETKNLLKKDWNIFSKNCNNSF.AKCSS.........................................................
G3RJD0_GORGO/41-180 ..............................HMIGSGHLQSLQRL............IDSQM.ETSCQITFEFVDQEQ...L....K.DPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIV...QL....Q....E....L....S.L....R....L....K....S....C...F....T...K...D..Y..E....E...H....D....K...A...CV...R...T..F...YET.PLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSF.AECSS.........................................................
A0A7K8RYG0_9PASS/1-130 .............................a--------------............-DTQM.QHPGRVSFKFIDKMQ...L....N.DSICYVKAAFPLMGKILERT-EFKKNSSNAKKMK...IV....R....E....MykhiD.E....N....V....D....P....C...I....R...E...E..D..D....E...Er.mlS....Q...M...CF...K...E..F...TTS.PYEMLVLVKDFFQDIKRLLQKR-ETFEKDCSQVY.R----rvc......................................................
A0A8D2D319_SCIVU/41-180 ..............................HMIGNGHLQFLQQL............IDSQM.ETSCHITFEFVDQEQ...L....K.DPVCYLKKAFLLVQDIMEDTMRFKDHTPNANAIL...RL....Q....E....L....S.L....R....L....K....S....C...F....T...K...D..Y..E....D...N....D....K...A...CV...R...T..F...YET.PLQLLEKIKNVFNETKNLLEEDWNVFSKNCNNSY.AKCSS.........................................................
A0A3M0JEH8_HIRRU/42-186 .............................q-IITERHLAELEEL............ADTQM.QHPGRVSFKFIDKMQ...L....N.DSVCYVKAAFPLMGRILERT-EFKENSSNARKMQ...TV....R....RmynsI....D.E....N....V....D....P....C...I....R...E...E..D..D....E...Er.tlS....Q...M...CF...K...E..F...TTS.PYEMLVLVKDFFQDIKRLLQN-QETFEKDCSRVY.R----racp.....................................................
A0A673VI47_SURSU/46-153 .............................q--------------............-----.--------------Q...L....K.DPVCYLKKAFLLMQDIMEDTMRFKDNTPNANFIV...KL....Q....E....L....S.L....N....L....R....S....C...F....T...K...D..Y..E....E...Q....D....K...A...CV...R...T..F...YET.PLQLLEKIKNVFNETKNLLKKDWNVFSKNCNNSF.AKCSS.........................................................
#=GC seq_cons ................................lsttHL..lppL............hDoQM.ppssploFcFl-cpQ...L....s.DsVCYVKAAFPLltcILEcThcFK-NSsNApthp...pl....p....c....l...........p....l....c....s....C...l....p...c...-.....-....E...c....s....p...h...Ch...+...p..F...ppo.PhphL.hVKshFp-hppLLpp..phFpKsCspsa.t.............................................................
//
