#=GF ID CTD2
#=GF AC PF20278.2
#=GF DE C-terminal domain 2 of the ABC-three component (ABC-3C) systems
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Chuguransky S;0000-0002-0520-0736
#=GF SE Aravind L
#=GF GA 25.00 25.00;
#=GF TC 25.70 99.00;
#=GF NC 22.10 24.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 32894288
#=GF RT Comprehensive classification of ABC ATPases and their functional
#=GF RT radiation in nucleoprotein dynamics and biological conflict
#=GF RT systems.
#=GF RA Krishnan A, Burroughs AM, Iyer LM, Aravind L;
#=GF RL Nucleic Acids Res. 2020;48:10045-10075.
#=GF DR INTERPRO; IPR046918;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC C-terminal domains (CTDs) of ABC-3C systems, contain distinct
#=GF CC patterns of charged and polar residues and are not yet unifiable
#=GF CC with known domains. These domains are found at the C-terminus of
#=GF CC the effector component of the systems, which are upstream of the
#=GF CC Middle Component and ABC ATPase components on the genome. Due to
#=GF CC the typically large size of these CTDs relative to the actual
#=GF CC effector and MC domains, the CTDs are predicted to serve as the
#=GF CC platform on which the remaining two components assemble.
#=GF CC Therewith, conformational changes transmitted by the ABC
#=GF CC ATPase-mediated detection of invasive elements like DNA viruses
#=GF CC would result in an unfurling and activation of the
#=GF CC CTD-associated effector [1].
#=GF SQ 26
#=GS A0A7S8IRZ5_9HYPH/510-770 AC A0A7S8IRZ5.1
#=GS A0A0L7TGE0_9GAMM/284-614 AC A0A0L7TGE0.1
#=GS A0A0B5S0N2_9FLAO/283-616 AC A0A0B5S0N2.1
#=GS A6TV44_ALKMQ/278-609 AC A6TV44.1
#=GS A0A5C6E7K4_9BACT/220-555 AC A0A5C6E7K4.1
#=GS A0A843BCN4_9BURK/150-362 AC A0A843BCN4.1
#=GS A0A3N1X3M7_9BURK/462-788 AC A0A3N1X3M7.1
#=GS A0A4R0XFE3_9BURK/484-767 AC A0A4R0XFE3.1
#=GS A0A0F4PQX9_9GAMM/272-606 AC A0A0F4PQX9.1
#=GS A0A225D8N6_9BACT/236-573 AC A0A225D8N6.1
#=GS A0A0Q5RBF9_9SPHN/452-778 AC A0A0Q5RBF9.1
#=GS A0A418WGN0_9PROT/469-772 AC A0A418WGN0.1
#=GS A0A6L6PY67_9BURK/482-806 AC A0A6L6PY67.1
#=GS A0A2G8T1J2_9BURK/461-788 AC A0A2G8T1J2.1
#=GS G2FKR9_9FIRM/282-613 AC G2FKR9.1
#=GS F4QFZ1_9CAUL/332-639 AC F4QFZ1.1
#=GS A0A2N7WU69_9BURK/461-787 AC A0A2N7WU69.1
#=GS N2IIR5_9PSED/291-624 AC N2IIR5.1
#=GS A0A840Y5C5_9PROT/463-790 AC A0A840Y5C5.1
#=GS A0A1G7EN77_9SPHI/278-602 AC A0A1G7EN77.1
#=GS A0A1G6ENQ4_9HYPH/489-816 AC A0A1G6ENQ4.1
#=GS C3MFA3_SINFN/459-785 AC C3MFA3.1
#=GS A0A4Q4B1X6_9BURK/462-788 AC A0A4Q4B1X6.1
#=GS A0A133XDX9_9RHOO/296-629 AC A0A133XDX9.1
#=GS A0A7H0H1H6_9BACT/279-605 AC A0A7H0H1H6.1
#=GS A0A520FRP1_SPHSX/528-854 AC A0A520FRP1.1
A0A7S8IRZ5_9HYPH/510-770 ................................................................addmvrlsk--------------...---------...---------------------------------......--------------ASGGKITLSLGATVQDAWKSRLPNAAA......AMTAA....SR-----...-YPYRLVStISIREHVDASLVRQLEAILVAAQAVGT.CDTLGKI....AADVFAEVLATWAGWRQTLDASPALRRDFLAWLGNIGpESAKSWSGDV.AVLERMA.------GALVLILATHLGEPLQ......PASVPRGNLSF.....DEN-.GHALGSSa.dkLDDGGLL-..TEWNLPEHWDVDALILS-RSSEVSVTGPDDTILNGGDPGT-GL.DIARRTKPAIVRNDGPWRTALKTG.LPAWKAAVK..
A0A0L7TGE0_9GAMM/284-614 .........................................................................GTLDLAGPTARSAK...-GVVEHMWSsepGNRKLRVYANYSSPTGDNLTLLTAIVRMALHLP.....qGSHGLMLGEPAWRSSVGHEIGHTLGCAEHDFSDLPWLENAE......RLVCA....QDHEFKT...LSAARGEA.EALAEAMDDVLWQRLLQGVSAKLGSIS.-------....DSALADAMETVWQSWLIGFTAAPESRRKFMDQLLYPK.TERKNEKHAL.RLGLRTL.NLLVTAVETLLLVAVGFPEGSNnw.eyfQEGGPVLNIAL.....KYWS.GPVGGFS....--GVRELSddPLIAVIGPDPDPIVILSGVSTSPTELLNIGMADDAETVTS---.MAAERQPHLLVTRSGMFRH-LQNGtLNSVRQHF-a.
A0A0B5S0N2_9FLAO/283-616 .........................................................................GIHDLESNTEIERP...CKTIPLLWS...NERSRNLNINIAKVNDPLTPIHESIFQLAIHLD.....gNVNGFCANWDGWKVYIENKIGGTFGVREDDFEGIRISNNNA......SFNAS....GGKIMNT...HAEREAFA.KEMNHQMTKETWKLVSEKISWRISQMV.TSQ----....SPELRDAVEVRWNVWQDIITKDESILIPLLKRIVHPN.AEGEEILGHL.RIGPKTK.LLIADALFTCLLISVALGSIDAgi.mktEDGLSIGAIGL.....SWWS.GPAGKTRk.irRIDEE--E..SIDDLIGKETYDILILSESEQPEGEIYKQSISDSVKIDHS---.LAAGNNPKLLITKNRIFNSIIKKGsIDELKTYLK..
A6TV44_ALKMQ/278-609 .........................................................................GTNDIELNTEIERP...NFVIPKLWN...--GTLLQNLKINAELSDRCGVSDSLLRLAIHQT.....gNSNTHCVNSAVIRSRINDKIGGTLGLEINDVQTLSIVENNE......NFRCE....EIKQLSS...RAENRNYS.DNMEKTMHLETWNKVSINIEELISGMY.NIH----....STTLQDQLEARWEIWKKKLNNDAQGIGELLKSIVHPR.AEGESINGML.RVGMRTA.QLLAESLFNLLIISIALDPENNgdwkkiNDKLAPVAVGL.....RYWS.GEAGKQRkvkaIDEDGNI-..----IIGKETANALIFSKVTSPPNEMWNDLISYSK---DQVQNsIADGKTPDLIITNCVEFRKLINKGdIEAVRNYVK..
A0A5C6E7K4_9BACT/220-555 ........................................................................v-SDDRGCRTNMDEH...--LILSVWQ...-DGLTGLWC--NILPDESPILTSAIERIVVQSPfataraNTELHFMGAAAWRSRCE--CCTKEWVPVDGVSIKKTLSKYAfvelgdEPIPL....GGLR---...FNNIDELA.DHLKSQCNKWAFRRLRERVSEAFDNPV.GELHYEI....ASDLVVPMRKLWNNWLNILKNDSSTLHHFFGLMLCS-.DGGVLMAESAaGTGPETIdACVLHATVYSLAVCVALPEKLS.....sLRVQSPGNLGQ.....DDMS.GHSCGIQ....IMSGKTI-..RMADRSHKWKTPFVMLPHLHTLWEVFRVTEARLDQ-EVNPSGRsFHQEPTRTLVLPGDCELMVAIEQG.INTLRAVLE..
A0A843BCN4_9BURK/150-362 ...............................................................gthdlvgtpt----------VLPPnpaAQIVSHHWResiPNRRLRLHAEYVRPN-KALTLPSAILRLALHLK.....hGSESMLLGEAAWRQGIRNELRGTLGDTERDLDNLPWFDNTE......PLLCA....MGRELSS...PVDTLAES.DDLHYAMNDAVWQQLQVCVGQKINDIN.-------....DHDLLVAMAEKWKIWQAELNKDPDARFHLFEQMMYPQ.TEGINAKHAL.RIGPRTM.ELMEAAIM--------------......-----------.....----.-------....--------..-------------------------------------------.------------------------.---------m.
A0A3N1X3M7_9BURK/462-788 ........................................................................a-AGRVNWSGGIGPD...--MIAACWA...PGSVVALHC--SVSAIDAGRLVHAFARLGAHAP......GITLFVRDAVRWRSALDALWQEPTHPGP-GLQFRCAVEQWR......DPPAL....EPLV---...EIPIADLA.ETINDRLDAETLRELHGTLFDILGPPA.LATGWLI....EQALRQRLLELWQAWFDTLTADSSKRRRFLRLLANASdKMEADYTSLV.GVGLRTVsPHLTLPTIFGLAFATCSGRAVE......PAMQHPGNVAI.....DMLT.GHACGVE....WINKRTVR..GSTVGMQTWTTTVVLLSQLGETVQMMEG-DVRLDQEVTDPPKVgVPSLSERPIVIGADDAFLSAMEEG.SPAVQQFFE..
A0A4R0XFE3_9BURK/484-767 adqceqleapvtihlalppgvvtdesailrlsrasngrihlttvaehaahgpqiapgiavaptgdpryrgrvl--------------...---------...---------------------------------......-----------------------------------------......-----....-------...------DP.SFLQDKLDACFLRLLDNSLRVIIASGT.STTLHKI....DESIRQAVASTWDVWSATLHGAAGLRFDFLRWLANIEqGARTPWSGDH.AQLPRMA.------AALLLMLATHLGEPLA......PASIKRGNLTF.....LGNAeALGSGCD....TIEGGPL-..TIWDQPDQWDVDALILSGSA-EVEVYSSDDTLLNAGSIGL-GL.RNARRVRPAIIRNDRAWRQKLNGP.LATWKQAVQ..
A0A0F4PQX9_9GAMM/272-606 .....................................................................gtls-----GHSEDIEPP...SLVVENLWNk.sNDRNFELCVKHPSNIDTLCSLDLSLVRLALHTS.....nGVSIVHNNPSAWKKDIAHAIRLTLGTTPTDFSNTTIVNDYE......EQSPI....DHRYLSK...SSEVKSEQ.IQLTKKMDNLTWEKTKDQVDDYIIELE.-------....SGEVQNTAEAIWTKWKNDIDADPSLQASSLSDMMYAI.VEGNKDIGQL.RAGPMTV.HLLSEAFGLLLFLAIGLDAEKKgw.refCSEYSVRTIAL.....AYWS.GSQVTPSkprkFFEADKRA..ERAELLGKETSNILVLPQTTASSSTVLGHTLASSESDGDR---.IADTRSPKSVITKSFEFIDVIESNsIENIKNFVQ..
A0A225D8N6_9BACT/236-573 ........................................................................a-HGKFRWRGGIAPV...--QFGLLWK...GRTDFLIAY--EPAQTRCRDVSDALLRAAIHGS......GGTLFVAEPDRWKERSTEIVNKCLG-TNWDRSSPSLAAATAr...twGLQPLteyeDAEYLVE..kEYSPTELS.SILNTVMDLVLLERLSEFASEMLVDGKsGELAMTI....ESELATEMWVVWQEWEATLRDQPELLSHFFRVMMSKA.DVKQLQFAQA.RVGLHTLvPCLLRSVIFALAIRVCLPWDFRp....vMDERHANIVAR.....HGY-.AHLCGLQ....LIEAVMIV..QKVQSL-MWETDYVILPHFTDPGEDIPSLSKSFMNGESKFSRLdKPTAGSP-LFLTGDGAFLRAILAG.KHDLQAHLQ..
A0A0Q5RBF9_9SPHN/452-778 ........................................................................n-NGALRWSGTAAPA...--EITSPWA...DAGSLEIAC--PDAPADLGPTSAALIRAAAHSR......-RITLIADPASWNREAQRLTALSL--QAEGMPMPRIENRQT......GGNTR....DPL----...PLPAAQLA.SRLNQAMDRWMLDAIHRHIEAYCATGQ.-DFGWRIgieaHDDLRHAMAAVWQGWHASFIADPALLARFLQLMVCALdADDSLDSASV.LVGPITL.DALIRGTAVACMIASDWQATT-......PHGVRPGNLKRqr.aaGDWC.GHSCGAS....RIDGKPL-..ALCAADFMWQTEFVILS-LQGSLKVASEAEEAFSTLDPSQPPL.TDTAGSGQLIMTIDDALRDAAKAG.PAALHALLE..
A0A418WGN0_9PROT/469-772 .................................................................gvdpaahv---------PVEQG...SHRLLDVAD..qCERLTSTIVLHLAAAPAKIPASADIVRLARASG......GRITLAAGPNGL--------------VDWQKIMPTIAA---......APSAV....SH-----...YSALALDL.TGLAGAIDACLLRLLDQRIRSALASHH.CDTLGPI....NASIAGAIGPTWTAWHASLTADKALLDAFLRWLANVEqHEHTRWNGDHaRISHLAT.-------ALVMMLATHHGEPLE......PALVDRGNLKF.....SHNAvALGSGCE....MVGRQPI-..AIWDQPDQWGVDALILS----GSAEVEVMDPPGRVLDGGKPAMgMAAARRVRPVVIRNDKLWRARLTNdLATWQTAV-a.
A0A6L6PY67_9BURK/482-806 .......................................................................ng--QNVHWSGALGSK...--DIQALWD...TERPYKIIL--HDDPDALGEVANAILRVACHSR......-NVTLYADPVHWRGFVRQIVMESL--HAKGISVPPICADFP......GGGTE....DAR----...EISKVRLA.KELHAGLDAWMLRRIHAHLEEYFRSGS.-DPGRAIgldiAQDLRQQMATIWSDWYVEFTDTAEVLKHFLCLMMCAA.DDD--GAAQV.LVGPEKL.PQIIRGTVVSLAIASAWTATE-......PKNERPGNLRRdlgenAVWA.GHSCAAD....LINGKSI-..LLQAGTFMWQTDFVILA-VEGTVEITRSAETAFAQANVDQPSF.SEPFGCEPLVLSISVAFSRAVEAG.TAALIGM--lg
A0A2G8T1J2_9BURK/461-788 ........................................................................v-SGRIVWAGDVSLN...--NIIQLWA...GGSSITVHC--DINAANASMLMPAIARIGVHAQ......DFVLYARDFAGWQAGMLGLCSDRFLPGA-DLNFCCLIKGWL......PPPPG....LQVH--S...EQPIDEVV.RTVHDQLDADLLQRLHDSIFGILGPAE.IATGWPI....EPALRQALWELWIQWHAELTANPAMRQRFLRLLASVNdQIDAGDGGLV.QLGPKVMrPYLVKPTLFGLAFAACSDRAMG......PAGRHPGNIAF.....EEVT.GHACGVG....WINRRELR..GRAAAGQSWTTNVVLLSQLQEAVQLLEG-DQRLDQNLTDQARIgLISLADKPIVIGANEDFLMALQSG.IPTVQHFFQ..
G2FKR9_9FIRM/282-613 .........................................................................GINDLKDNTEIERP...SVIVPALWTs.gNPNARELKI--EGACIENCCVSQSLMRLSLHPQ.....gLFGIICSDKPSWENAIKNKTGGTLGLLKNDLDDLRILGGLN......QSTHS....EKKELAA...IGEQEQFA.NELQNEMYKCSFEHIKTIIFNIIRDMT.-------....NGDLRTEVEKRWITWKPLLENNIEEQKKLFTKMLHPQ.AEGKSISGEL.RVGLRTA.VLLAESIFLLLVVSVCLGDDKNrswkavKDQLKVNSIGL.....AYWS.GPAEEFK...kIMEIDADE..GIGKLLEKEPGEILIIPQSELPEAYVFNDDIFGGFTKGCL---.LSHPRYPKLLITQGWEFKRKLKSGsISDIREYLQ..
F4QFZ1_9CAUL/332-639 ........................................................................t-TIIVNWDDSVQKPtqqGTQTIQEMCsrcSDIEAPLVIHLALQRSRIPEFATELERFARASG......GRILLEASPATF---------------------PSWSD---......SGVPV....NPQLTFVspyRSNELPTV.AELRKLFDTYLIQRLDAAI-AHCAAGS.CGVFKDV....HPSLYGTFAETWSEWKLILEGDHELRGKFLRVLARAI.DDGSGWDGAEdGFVDLVA.-------GSFLIMAAHAGRSAT......PTNSRHGNVIF.....QGDAiGVASGCK....ILDGKLI-..SDVPADEFWSADALILAGAYEEMRT--GRDLITDGGVSSRTL-.LTSERVRPAIIQNTRRWRDALKGD.LRAWIANIE..
A0A2N7WU69_9BURK/461-787 .......................................................................ng--ADIEWLSPVTPG...--EAERYWV...GGRAFAVYA--DISAADAGPLVAAIARIGAHVP......GFVIRTRDAHGWRAALNKLCAARELPGP-GLAAPYVVHDWA......APPPL....DIQA---...TVGPALLA.ETVHAALDGEMQRQLRGALHEILGPAA.VEMGWPI....EPALKARLWARWEIWHGALLANAVTRQRFLLLLATEQdHADLRDGMLV.RVGPKILrPFLTKPALFGLTFAVCSGHALA......PAAGPPGNVAT.....HGIT.GHACGVG....WIGGRELG..ASCAMRQSWSTGIVLLAQLKDAFRLIEG-ELRFDRAAGDPPRVgMTSLGEGPLVIGADDVFVTALEAG.EQSVQDYFQ..
N2IIR5_9PSED/291-624 .........................................................................GTHNLNGTTGLPVShaaTEIVGHHWTaggNNRKLRLHATYCPPTPNTVALPSAILRLALHLK.....sGSHCLLLGEPLWRQGAGNELGRTLGISESDLDELPWIDNSE......ALSCA....SGRELST...ILEARDES.SALHRAMNDLVWEQLQSRITTRLNSVS.-------....DTPLLAALEPKWRSWAAELTADATARDLLFEQLMYPK.TEGLDGKHAL.RVGPRTA.DLMETAILMLLLVCVAIGNDDGnw.leiPDLGEVRSIAL.....KNWS.GASGDNS....--GARPVA.dELTAVLGPSPAPVVILAGVEGSPTSLLESGMADDFETSNS---.MAAERQPRLLVTR-FEVLKYLRTGtLTQLQRQFK..
A0A840Y5C5_9PROT/463-790 ......................................................................hgg---EARWTGDVPLA...--GAATAWD..aAGPPVTITV--PAIPADLGALAYALGRLALHAQ......-GGVMHVDVARWGAFLDGITTASRNAEDLDRPTLRPVD---......GSSDL....APE----...RLTTDNMA.ARLGATLDRRCLAMIDEHLAGLLERGE.-DPGHVVdlapAPEVAAAMRAIWAEWKAAFDRDPALLARFLRLLVCAQdGTAAADEART.LVGPRKR.KLLVRATGAALAVATGWASTA-......PHPDEPGNLTHqt.gaHART.GHVCAAE....RIGGRTT-..ATEAASFLWRTDFVVLPMLTSPVAVARRAEERFDATDESEPTF.AKAGAGPSLMLSVDPRFKAGVAAG.LAQIAGL--ls
A0A1G7EN77_9SPHI/278-602 .......................................................................gi--CD-PDFGHIERA...EKVVIETWNe.qKPSELKLHCQSPRHE----PLPSALRRLILHMP.....gTSVAYIHDLALWRERTLALIGGTLGKDEEDCRTLPLIELGA......RQAPA....DIREIPN...SGDADSEG.RSLDQQMDDLTWAVIKNKISDKLLVIP.-------....AGELRTAMEARWQCWLAALDADTTVRTGFCRQMLVPH.AEGKAIAGSL.RHGPKTA.LLVSKGIILLLAVAVAVSANDEgw..qkLSGTTVGTRAI.....QVWS.GPADDNH....--TLRNLAdeGIEVLIGREPFKLLILSAVESSISEITGSSL----SDGQEPSY.TLADGHQPMILTHSGKIKEALRKGdLAMLRTYL-p.
A0A1G6ENQ4_9HYPH/489-816 ........................................................................e-AGYVRWSGAIPAE...--QLLRSWS...EHQPFEIII--PDGPEDLGAVAGAVLRVACHSS......-SCRLHAAPGQWRQHVRALSVDS--PHAEGMGMPAILAGNP......GGAAQ....NPV----...RLPPDILA.RRIHRSLDSWLLERLDAHLQPFFASNA.-DPGRPInlkiADDLRAAMAATWADWYALFSDEPALLGHFLRLMICAVeDDHNRDAAQI.LVGPNKL.GCILRGTAVALAVAAAWEGTS-......PKGIKPGNLVRlrngdSEWA.GHGCAAD....MINGEEM-..SLCAASFMWQTQFVILV-VKNAIEVSRIAERPFARIDTDQPGL.SETAGSGPVIMSISRDFVDAAAAG.LPEMCVLL-d.
C3MFA3_SINFN/459-785 ......................................................................qgs---NITWSGDLAPT...--DIDTLWR...GNDGLSVYV--DVAAADSDGLIAALARLGCHAA......SFHLYARDAQGWRTSMTSLCASRSLPGP-DMGTRCIVNDWE......DPPAV....AQRA---...TSPIADLT.RIVSDRLDLETLSQLHGALYDVLGPPN.VEIGWLI....EARLKGQLWARWLNWHPVLQAESATRRRFMLLLVTEQ.DHDNITPELLvRVGPRSLrPFLTKPTIFGLTFAVCSEHAVS......PIAVAPGNMAG.....GGLT.GHACGVG....WIQGRDLS..AGFAAAQAWTTGVVLLAQLREAFRLAER-DVRFDHAPGDQAKVgDVLLDQEPLVIPADELFVIALEAG.EQSMQQHL-r.
A0A4Q4B1X6_9BURK/462-788 ........................................................................a-AGRVAWSGGIGPD...--GIEACWA...HDSVVALHC--SVSAIDAGRLVQAFARLGAHGP......GITLFVRDVARWRSALDALWQDPTHPGP-GLHFRCAVEQWR......DPPAL....APLV---...ESPIADLA.ETINDRLDSETLRELHGALFDILGPPA.LATGWPI....EQALRQQLLELWQAWYGTLSADRSKRRRFLRLLANTN.DKVEADFTSLvGVGLRTVcPHLTLPTIFGLAFAACSGRAVE......PAMQHPGNVAI.....DTLT.GHACGVE....WINQRTVR..GRTVGMQTWTTTVVLLSQLRETVQMMEG-DVRLDQVATDPPTVgVPSLSERPIVIGADDAFLSAMEEG.SPAVQQFFE..
A0A133XDX9_9RHOO/296-629 .........................................................................GTHNLNGTTSLPVPhaaTEVVGHHWTaggNNRKLRLHATYCPPTPNTVALPSAILRLALHLK.....sGSHCLLLGEPLWRQGAGNELGRTLGISENDLDELPWIDNSE......ALSCA....SGRELST...ILETRDES.SALHRAMNNLVWEQLQARITTRLNSVS.-------....DTPLLAALEPKWRSWAAELTADAAARDSLFEQLMYPK.TEGLDGKHAL.RIGPRTA.DLMETAILMLLLVCVAIGNDDGnw.reiPNIGEVLSIAL.....KNWS.GASGDHS....--GARPVA.dELMAVLGPSPAPVVILAGVEGSPTSLLESGMADDFETSNS---.MAAERQPKLLVTR-FGVLKYLRTGtLAQLQGQFK..
A0A7H0H1H6_9BACT/279-605 ........................................................................g-IHD-RRFGFIEHP...SSIVPTLWG...PPGAGILKY--YSKDHSSGPLPKAIIRLLLHIQ.....pAAVAHVSDKSAWSIVAKNLVGETLGISEDDCEALHVQDDSD......CYVSS....DKRVLEK...LRDSEAEA.ELLSIEMHKKSWELIGNHILRKLEKLP.-------....SSELRDAVEDRWQLWKDELDKDIDKQKLLCQSMLHPK.AEGEDISAEL.RFGPKTT.SMVADGILLLMVVVICIGDKDSnw.dtiDTQLTISVKAL.....SHWS.GPFGQTR....RVRKITED..GVSALIGKEPSKILVLSRIDASSSTVLQESLIDDT---DFAGS.MASPRQPILLVTNNPTVNRLIRQGiIADIKEYL-n.
A0A520FRP1_SPHSX/528-854 .......................................................................gp---NIRWSGAVPAD...--QLIRSWS...EQQPFEIIL--PDAPGQLGAVAGAVLRVACHSG......-NCRLHAAPGLWSQLVRELSLES--PHAEGMAMPAIVDGNP......GGAAQ....DPV----...PLPPDILA.RRIHRSLDAWLLERLDTHLQPFFASNA.-DPGRPInvkiAQDLRDAMAAIWAAWHASFTDDPALLNHFLRLMICAVdEDDRRDAAQI.LVGPSKW.PVILRGTAVALAIAAAWDATS-......PKSARPGNLVRlrdgdSEWT.GHGCAAD....MINGDEM-..SLCAASFMWQTQFVILV-VKTAIEVSRIAERPFAQIDTDQPGL.SDTDGSGPVIMSISRDFIDAAAAG.LAELRALL-a.
#=GC seq_cons ........................................................................s..tplphssslt.s......l.phWs...sspshplhh..sssssshsslssAlhRluhHst......stthhhts.stW+pthpthhstohh.stpshshhsllss.t......s.ssh....s.p........hshpthu.ppLppphDshhhcpLcsplpshlssss..t.hh.l....sssLpsshtshWpsWpspLssDsshpp+FLchhhssp.s-spthsupl.tlGP+oh.shlhcuhhhhLhlAsshsps.t......PsthpsGNluh.....ptho.Gtususp....hlssctl...shtshhthWssshlILutlpsshphh.st-hthsttssspsth.hssttp..lllststtahpulcsG.lsslpshlp..
//
