#=GF ID CUPID
#=GF AC PF11819.12
#=GF DE Cytohesin Ubiquitin Protein Inducing Domain
#=GF PI DUF3338;
#=GF AU Assefa S;0000-0003-2178-533X
#=GF AU Coggill P;0000-0001-5731-1588
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE PFAM-B_2474 (release 23.0)
#=GF GA 22.40 22.40;
#=GF TC 22.40 22.40;
#=GF NC 22.30 22.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 30355448
#=GF RT INAVA-ARNO complexes bridge mucosal barrier function with
#=GF RT inflammatory signaling.
#=GF RA Luong P, Hedl M, Yan J, Zuo T, Fu TM, Jiang X, Thiagarajah JR,
#=GF RA Hansen SH, Lesser CF, Wu H, Abraham C, Lencer WI;
#=GF RL Elife. 2018; [Epub ahead of print]
#=GF DR INTERPRO; IPR021774;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC C1ORF106 also known as INAVA (Innate Immune Activator), is
#=GF CC identified as a risk factor for the chronic inflammatory bowel
#=GF CC diseases (IBD). Mice lacking the protein show defects in
#=GF CC intestinal barrier integrity at steady state and greater
#=GF CC susceptibility to mucosal infection. INAVA carries CUPID
#=GF CC (Cytohesin Ubiquitin Protein Inducing Domain). Three other human
#=GF CC proteins contain CUPID: FRMD4A, FRMD4B, and CCDC120- proteins
#=GF CC implicated in neurite outgrowth, and in human cancer,
#=GF CC Alzheimer's, celiac, and heart disease. All appear to bind the
#=GF CC ARF-GEF (guanine nucleotide-exchange factors) cytohesin family
#=GF CC members, such as proteins (ARF 1-4), which regulate cell
#=GF CC membrane and F-actin dynamics. INAVA-CUPID binds cytohesin 2
#=GF CC (also known as ARNO), targets the molecule to lateral membranes
#=GF CC of epithelial monolayers, and enables ARNO to affect F-actin
#=GF CC assembly that underlies cell-cell junctions and barrier
#=GF CC function. In the case of inflammatory signalling, ARNO can
#=GF CC coordinate CUPID function by binding and inhibiting CUPID
#=GF CC activity of acting as an enhancer of TRAF6 dependent
#=GF CC polyubiquitination. In other words, ARNO acts as a
#=GF CC negative-regulator of inflammatory responses. In summary,
#=GF CC INAVA-CUPID exhibits dual functions, coordinated directly by
#=GF CC ARNO, that bridge epithelial barrier function with extracellular
#=GF CC signals and inflammation [1].
#=GF SQ 3927
#=GS A0A8P0P635_CANLF/367-501 AC A0A8P0P635.1
#=GS A0A1S3ML93_SALSA/394-529 AC A0A1S3ML93.1
#=GS A0A7K5JKL0_9TYRA/101-235 AC A0A7K5JKL0.1
#=GS Q5T376_HUMAN/389-524 AC Q5T376.1
#=GS A0A0A0AGE7_CHAVO/349-483 AC A0A0A0AGE7.1
#=GS A0A2Y9R3M0_TRIMA/47-182 AC A0A2Y9R3M0.1
#=GS A0A7K4T1I9_9CHAR/407-541 AC A0A7K4T1I9.1
#=GS A0A3Q4GYD7_NEOBR/2-137 AC A0A3Q4GYD7.1
#=GS A0A3Q1FVB5_9TELE/2-108 AC A0A3Q1FVB5.1
#=GS A0A667ZHP9_9TELE/334-469 AC A0A667ZHP9.1
#=GS G3T5M2_LOXAF/101-230 AC G3T5M2.1
#=GS A0A7F8QF87_LEPWE/372-507 AC A0A7F8QF87.1
#=GS G1RNH1_NOMLE/342-477 AC G1RNH1.2
#=GS A0A8M1NI35_DANRE/341-476 AC A0A8M1NI35.1
#=GS A0A2I4BF30_9TELE/360-493 AC A0A2I4BF30.1
#=GS A0A337SI15_FELCA/372-507 AC A0A337SI15.1
#=GS A0A8C4QHL4_EPTBU/5-130 AC A0A8C4QHL4.1
#=GS A0A6P8TUZ3_GYMAC/2-108 AC A0A6P8TUZ3.1
#=GS G3WVZ4_SARHA/372-507 AC G3WVZ4.2
#=GS A0A7J6CLV0_9TELE/2-137 AC A0A7J6CLV0.1
#=GS A0A5F9DHZ9_RABIT/356-491 AC A0A5F9DHZ9.1
#=GS A0A6P3WUP4_DINQU/3-126 AC A0A6P3WUP4.1
#=GS A0A6P3GCR0_BISBI/2-68 AC A0A6P3GCR0.1
#=GS A0A2K5ENR0_AOTNA/372-506 AC A0A2K5ENR0.1
#=GS A0A8C4ZSR4_GADMO/68-203 AC A0A8C4ZSR4.1
#=GS A0A4W2DKY1_BOBOX/395-529 AC A0A4W2DKY1.1
#=GS A0A8D2IMW9_UROPR/349-483 AC A0A8D2IMW9.1
#=GS A0A8C5N9E8_9TELE/341-476 AC A0A8C5N9E8.1
#=GS A0A7K9J7Y8_9CORV/317-452 AC A0A7K9J7Y8.1
#=GS A0A8B9P464_APTOW/37-172 AC A0A8B9P464.1
#=GS A0A5F9D7V1_RABIT/372-507 AC A0A5F9D7V1.1
#=GS A0A4U8UXX3_STECR/410-548 AC A0A4U8UXX3.1
#=GS A0A5E4MDB1_9HEMI/1-117 AC A0A5E4MDB1.1
#=GS A0A7K7DD76_PHEME/101-235 AC A0A7K7DD76.1
#=GS A0A8C3VJZ4_9CETA/87-216 AC A0A8C3VJZ4.1
#=GS A0A665UYL8_ECHNA/353-489 AC A0A665UYL8.1
#=GS A0A2I3LMX2_PAPAN/300-447 AC A0A2I3LMX2.2
#=GS A0A2I2Y428_GORGO/166-220 AC A0A2I2Y428.1
#=GS G5ECS7_CAEEL/37-160 AC G5ECS7.1
#=GS A0A3S1AW60_ELYCH/17-156 AC A0A3S1AW60.1
#=GS A0A8B8BHK8_CRAVI/462-595 AC A0A8B8BHK8.1
#=GS A0A6P9AFB9_THRPL/17-149 AC A0A6P9AFB9.1
#=GS A0A6P6H8R9_PUMCO/395-529 AC A0A6P6H8R9.1
#=GS A0A7L3YHX3_FREGA/316-451 AC A0A7L3YHX3.1
#=GS A0A674P6Y0_TAKRU/24-134 AC A0A674P6Y0.1
#=GS G1NB47_MELGA/395-529 AC G1NB47.2
#=GS A0A8U8BX13_GEOPR/47-182 AC A0A8U8BX13.1
#=GS A0A6P8S859_GEOSA/356-491 AC A0A6P8S859.1
#=GS A0A2I4DBG6_9TELE/6-97 AC A0A2I4DBG6.1
#=GS A0A6P8J2E1_ACTTE/344-481 AC A0A6P8J2E1.1
#=GS A0A0V0YB57_TRIPS/393-532 AC A0A0V0YB57.1
#=GS A0A6P5LKT7_PHACI/26-151 AC A0A6P5LKT7.1
#=GS A0A8C0VFS8_CYACU/47-182 AC A0A8C0VFS8.1
#=GS A0A6P6MZP0_CARAU/364-499 AC A0A6P6MZP0.1
#=GS A0A8J0V7H9_XENLA/393-527 AC A0A8J0V7H9.1
#=GS A0A5F5XQM5_FELCA/268-402 AC A0A5F5XQM5.1
#=GS A0A6J2ZZV4_VICPA/394-529 AC A0A6J2ZZV4.1
#=GS A0A8C7H0I3_ONCKI/336-471 AC A0A8C7H0I3.1
#=GS A0A7L1KQH9_HIMHI/322-457 AC A0A7L1KQH9.1
#=GS A0A3B5QMV2_XIPMA/4-101 AC A0A3B5QMV2.1
#=GS A0A669QYK6_PHACC/2-128 AC A0A669QYK6.1
#=GS A0A096M7D5_POEFO/395-529 AC A0A096M7D5.1
#=GS A0A672UFM1_STRHB/150-284 AC A0A672UFM1.1
#=GS A0A8D2KF57_UROPR/389-524 AC A0A8D2KF57.1
#=GS A0A2K5RQ46_CEBIM/47-181 AC A0A2K5RQ46.1
#=GS A0A667GEG3_LYNCA/344-479 AC A0A667GEG3.1
#=GS A0A8B9RU81_9AVES/59-183 AC A0A8B9RU81.1
#=GS A0A7L2MJ47_9PASS/1-127 AC A0A7L2MJ47.1
#=GS A0A3Q4H6J3_NEOBR/47-180 AC A0A3Q4H6J3.1
#=GS A0A8C8I0Z0_ONCTS/2-137 AC A0A8C8I0Z0.1
#=GS A0A2I2U7H4_FELCA/349-483 AC A0A2I2U7H4.2
#=GS A0A669NV31_PHACC/394-529 AC A0A669NV31.1
#=GS A0A7J8BC34_MOLMO/47-182 AC A0A7J8BC34.1
#=GS A0A8B9I811_9AVES/373-508 AC A0A8B9I811.1
#=GS A0A8C4PGU8_EQUAS/76-154 AC A0A8C4PGU8.1
#=GS A0A836K9V3_9HYME/21-155 AC A0A836K9V3.1
#=GS A0A8C7FA28_ONCKI/47-182 AC A0A8C7FA28.1
#=GS A0A665TVJ0_ECHNA/330-463 AC A0A665TVJ0.1
#=GS A0A8J5A433_9CHEL/386-524 AC A0A8J5A433.1
#=GS A0A7K8EYH6_9CORV/101-235 AC A0A7K8EYH6.1
#=GS A0A7L0QDC8_SETKR/325-460 AC A0A7L0QDC8.1
#=GS A0A8V5FZ48_MELUD/394-529 AC A0A8V5FZ48.1
#=GS A0A8J4L225_EUDCH/322-457 AC A0A8J4L225.1
#=GS A0A1U7S1P2_ALLSI/287-421 AC A0A1U7S1P2.1
#=GS A0A6P8NFP8_GEOSA/66-198 AC A0A6P8NFP8.1
#=GS A0A7K7L3E1_9AVES/101-235 AC A0A7K7L3E1.1
#=GS A0A8C4H321_DICLA/354-487 AC A0A8C4H321.2
#=GS A0A5E4CFA7_MARMO/372-507 AC A0A5E4CFA7.1
#=GS A0A8B7T333_HIPAR/566-701 AC A0A8B7T333.1
#=GS H2M1I4_ORYLA/373-508 AC H2M1I4.2
#=GS A0A1S3P4W9_SALSA/2-137 AC A0A1S3P4W9.1
#=GS A0A484DHZ0_PERFV/2-137 AC A0A484DHZ0.1
#=GS A0A4W5L5Q5_9TELE/327-460 AC A0A4W5L5Q5.1
#=GS A0A7K9NV83_9CORV/1-111 AC A0A7K9NV83.1
#=GS A0A3P8YTH9_ESOLU/51-144 AC A0A3P8YTH9.2
#=GS A0A3Q1N856_BOVIN/341-475 AC A0A3Q1N856.1
#=GS A0A8C4BFR3_9TELE/363-452 AC A0A8C4BFR3.1
#=GS A0A7K9YTR6_9GALL/101-235 AC A0A7K9YTR6.1
#=GS A0A3Q4BAF8_MOLML/465-511 AC A0A3Q4BAF8.1
#=GS A0A674MK49_TAKRU/395-528 AC A0A674MK49.1
#=GS A0A8C5H1P7_9TELE/333-468 AC A0A8C5H1P7.1
#=GS A0A7N8X1Q1_9TELE/382-515 AC A0A7N8X1Q1.1
#=GS A0A6P8U425_GYMAC/353-488 AC A0A6P8U425.1
#=GS F7HKM7_MACMU/350-484 AC F7HKM7.2
#=GS A0A2K6QVG2_RHIRO/356-491 AC A0A2K6QVG2.1
#=GS A0A8B9J395_9PSIT/383-517 AC A0A8B9J395.1
#=GS A0A3Q3AG07_KRYMA/395-528 AC A0A3Q3AG07.1
#=GS A0A7K6DIB8_9PASS/321-456 AC A0A7K6DIB8.1
#=GS A0A8D0AMP1_SANLU/5-53 AC A0A8D0AMP1.1
#=GS A0A814XYE2_9BILA/364-496 AC A0A814XYE2.1
#=GS A0A7K7TXC9_9CHAR/322-457 AC A0A7K7TXC9.1
#=GS A0A484DGH7_PERFV/395-528 AC A0A484DGH7.1
#=GS A0A8C4RTQ5_ERPCA/341-476 AC A0A8C4RTQ5.1
#=GS H0WLA9_OTOGA/349-483 AC H0WLA9.1
#=GS K7GD41_PELSI/343-478 AC K7GD41.1
#=GS A0A672H2F5_SALFA/365-498 AC A0A672H2F5.1
#=GS A0A7L4EAM7_HIRRU/101-235 AC A0A7L4EAM7.1
#=GS A0A834C4S7_ORYME/6-96 AC A0A834C4S7.1
#=GS A0A093F1E6_TYTAL/103-237 AC A0A093F1E6.1
#=GS A0A6J2AL55_ACIJB/372-507 AC A0A6J2AL55.1
#=GS A0A6J0V191_9SAUR/356-491 AC A0A6J0V191.1
#=GS A0A7E6D0B0_9CHIR/62-201 AC A0A7E6D0B0.1
#=GS R7TXQ2_CAPTE/350-483 AC R7TXQ2.1
#=GS A0A8D0AQQ3_SANLU/341-474 AC A0A8D0AQQ3.1
#=GS A0A7J7QSN6_MYOMY/268-403 AC A0A7J7QSN6.1
#=GS A0A3Q1H1L6_ANATE/373-508 AC A0A3Q1H1L6.1
#=GS A0A7L3B1F7_9AVES/11-130 AC A0A7L3B1F7.1
#=GS L5L5S9_PTEAL/74-140 AC L5L5S9.1
#=GS A0A6A1Q6D7_BALPH/1-35 AC A0A6A1Q6D7.1
#=GS A0A1D5R287_MACMU/341-476 AC A0A1D5R287.2
#=GS A0A4Z2I658_9TELE/356-489 AC A0A4Z2I658.1
#=GS A0A6J3HFB3_SAPAP/2-129 AC A0A6J3HFB3.1
#=GS A6QPQ3_BOVIN/47-181 AC A6QPQ3.1
#=GS A0A7L3GH27_9AVES/1-114 AC A0A7L3GH27.1
#=GS A0A4W2BMB1_BOBOX/47-181 AC A0A4W2BMB1.1
#=GS A0A3S5ZPH5_BOVIN/2-141 AC A0A3S5ZPH5.1
#=GS A0A8J0SSC3_XENTR/352-487 AC A0A8J0SSC3.1
#=GS A0A8C5H2I8_9TELE/343-478 AC A0A8C5H2I8.1
#=GS A0A7K9BTS2_9PICI/1-32 AC A0A7K9BTS2.1
#=GS A0A7K7DDB1_PHEME/322-457 AC A0A7K7DDB1.1
#=GS G3RFN6_GORGO/349-484 AC G3RFN6.2
#=GS A0A8C3F5Q9_CHRPI/399-534 AC A0A8C3F5Q9.1
#=GS A0A091RD29_MERNU/78-212 AC A0A091RD29.1
#=GS A0A803WDI7_FICAL/363-498 AC A0A803WDI7.1
#=GS A0A3Q2WF98_HAPBU/2-137 AC A0A3Q2WF98.1
#=GS A0A7K9TYL0_9AVES/101-235 AC A0A7K9TYL0.1
#=GS A0A3Q2WWT5_HAPBU/336-471 AC A0A3Q2WWT5.1
#=GS A0A8B9PXL0_APTOW/150-284 AC A0A8B9PXL0.1
#=GS A0A8R1E269_CAEJA/382-515 AC A0A8R1E269.1
#=GS A0A2K6SFF9_SAIBB/372-507 AC A0A2K6SFF9.1
#=GS A0A0P7WYW0_SCLFO/1-118 AC A0A0P7WYW0.1
#=GS A0A7N6BRC3_ANATE/356-489 AC A0A7N6BRC3.1
#=GS A0A6P8ULE1_GYMAC/341-474 AC A0A6P8ULE1.1
#=GS A0A8C5CS54_GADMO/227-360 AC A0A8C5CS54.1
#=GS A0A226NI64_CALSU/2-128 AC A0A226NI64.1
#=GS A0A4X2KV34_VOMUR/86-159 AC A0A4X2KV34.1
#=GS A0A3Q2CCN9_CYPVA/362-495 AC A0A3Q2CCN9.1
#=GS A0A6P6RBV1_CARAU/357-492 AC A0A6P6RBV1.1
#=GS M7AV45_CHEMY/2-133 AC M7AV45.1
#=GS A0A6P6N0A2_CARAU/389-524 AC A0A6P6N0A2.1
#=GS A0A6J3A3W6_VICPA/2-129 AC A0A6J3A3W6.1
#=GS A0A8C9MXF3_SERCA/341-475 AC A0A8C9MXF3.1
#=GS A0A315W803_GAMAF/584-717 AC A0A315W803.1
#=GS A0A7K9HLI5_9AVES/1-87 AC A0A7K9HLI5.1
#=GS A0A7K5EIN3_POLCE/1-124 AC A0A7K5EIN3.1
#=GS A0A7K7T8X3_9TYRA/101-235 AC A0A7K7T8X3.1
#=GS A0A7N8X434_9TELE/2-108 AC A0A7N8X434.1
#=GS A0A671XBB5_SPAAU/393-526 AC A0A671XBB5.1
#=GS A0A8C5QVN3_9ANUR/340-474 AC A0A8C5QVN3.1
#=GS A0A5F9D6Y2_RABIT/363-498 AC A0A5F9D6Y2.1
#=GS A0A8C7C4K9_ONCKI/2-100 AC A0A8C7C4K9.1
#=GS A0A3P9DLP6_9CICH/341-474 AC A0A3P9DLP6.1
#=GS A0A212CA39_CEREH/50-106 AC A0A212CA39.1
#=GS A0A7J7WCL5_PIPKU/395-529 AC A0A7J7WCL5.1
#=GS A0A2K5NKQ0_CERAT/47-181 AC A0A2K5NKQ0.1
#=GS A0A8C6EZ70_MARMA/352-487 AC A0A8C6EZ70.1
#=GS H2N9T3_PONAB/356-491 AC H2N9T3.2
#=GS A0A4D9EMQ7_9SAUR/341-463 AC A0A4D9EMQ7.1
#=GS G1K8R5_ANOCA/341-476 AC G1K8R5.3
#=GS A0A6P6QD59_CARAU/2-137 AC A0A6P6QD59.1
#=GS A0A0D9RMX5_CHLSB/2-131 AC A0A0D9RMX5.1
#=GS A0A7L3L5W1_9CHAR/1-43 AC A0A7L3L5W1.1
#=GS A0A4Z2BAY7_9TELE/2-137 AC A0A4Z2BAY7.1
#=GS A0A6J2GSC2_9PASS/394-529 AC A0A6J2GSC2.1
#=GS A0A553P592_9TELE/292-425 AC A0A553P592.1
#=GS A0A3P8WNC1_CYNSE/4-107 AC A0A3P8WNC1.1
#=GS H3DKS5_TETNG/363-499 AC H3DKS5.1
#=GS A0A087YAV0_POEFO/78-213 AC A0A087YAV0.2
#=GS A0A3Q2E2U3_CYPVA/342-477 AC A0A3Q2E2U3.1
#=GS A0A8C5H7X2_9TELE/5-136 AC A0A8C5H7X2.1
#=GS A0A835NTJ6_9PASS/1-120 AC A0A835NTJ6.1
#=GS A0A3B3HY69_ORYLA/4-104 AC A0A3B3HY69.1
#=GS A0A671MD50_9TELE/46-179 AC A0A671MD50.1
#=GS A0A7K5IXQ8_TOXRE/101-235 AC A0A7K5IXQ8.1
#=GS A0A3P8U3A2_AMPPE/380-513 AC A0A3P8U3A2.1
#=GS A0A7L1USV0_SITEU/320-455 AC A0A7L1USV0.1
#=GS A0A8J6HPS7_TENMO/1060-1174 AC A0A8J6HPS7.1
#=GS A0A4W5QBF1_9TELE/395-528 AC A0A4W5QBF1.1
#=GS A0A8C4D6B2_9TELE/404-537 AC A0A8C4D6B2.1
#=GS A0A2K6U4C9_SAIBB/366-500 AC A0A2K6U4C9.1
#=GS A0A7L1WKA5_9PASS/1-134 AC A0A7L1WKA5.1
#=GS A0A673AGZ2_9TELE/104-161 AC A0A673AGZ2.1
#=GS A8Y219_CAEBR/322-452 AC A8Y219.1
#=GS A0A1S3HGT6_LINUN/386-523 AC A0A1S3HGT6.1
#=GS A0A8C5UQE9_MICMU/37-176 AC A0A8C5UQE9.1
#=GS A0A7K8GHU4_ORTSP/101-235 AC A0A7K8GHU4.1
#=GS G5B3A9_HETGA/87-216 AC G5B3A9.1
#=GS A0A6P5M0H6_PHACI/395-529 AC A0A6P5M0H6.1
#=GS A0A673N9R4_9TELE/2-135 AC A0A673N9R4.1
#=GS A0A8C4W3N4_9SAUR/176-221 AC A0A8C4W3N4.1
#=GS A0A6P8TRE7_GYMAC/341-474 AC A0A6P8TRE7.1
#=GS A0A7L1IL71_SMUAF/230-365 AC A0A7L1IL71.1
#=GS A0A7L2TTN4_POMRU/1-127 AC A0A7L2TTN4.1
#=GS A0A8M9QE03_DANRE/4-108 AC A0A8M9QE03.1
#=GS A0A3B5Q2R3_XIPMA/341-474 AC A0A3B5Q2R3.1
#=GS A0A7J7T1K4_PIPKU/39-178 AC A0A7J7T1K4.1
#=GS A0A1U7T8N9_CARSF/232-367 AC A0A1U7T8N9.2
#=GS A0A5N4CIA3_CAMDR/2-131 AC A0A5N4CIA3.1
#=GS A0A6P6NIV9_CARAU/67-180 AC A0A6P6NIV9.1
#=GS A0A672M1T7_SINGR/343-478 AC A0A672M1T7.1
#=GS A0A6J0DYL5_PERMB/352-487 AC A0A6J0DYL5.1
#=GS A0A8C9N0R1_SERCA/341-475 AC A0A8C9N0R1.1
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#=GS A0A671N7T4_9TELE/329-464 AC A0A671N7T4.1
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A0A3B5QQE6_XIPMA/357-492 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLRQRLEELKSIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.E..ELERLE.REFAIQSQITEAARRLASDPHVSS-k.....................................................
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A0A674CIP5_SALTR/47-182 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLKQRLEELKNIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GP..A..FK....LDEHKIK.P.K.............................R.EE.E..ELERLE.REFAIQSQITEAARRLAGDPHGS--sk....................................................
A0A4Z2ECP8_9TELE/1-101 ...........................................mmr-----------.-----.........-.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.LLA...ALR.ARQEALEETLRKRLEELRSIC..IR...ES..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GT..A..FK....LDEQKII.P.E.............................G.EV.-..------.-------------------------rlqlfpslhvl...........................................
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A0A6G1Q453_9TELE/341-474 .............................................g-LKNNFITASN.GSLVS.........T.......G............S..A.D.S.E..M..S..E.E.....Q...K......K.E.KLS...ELR.KKEQEIQDILAKKTKELKKIC..LR...EA..............EL........T.GKLPKE..Y..P..LSS.GE....R.....P..PHVRRR..V.GT..A..FK....LDD--LF.P.Y.............................N.ED.P..FLRNLE.SRFALQQKIVEAAKKLANEPELCKT......................................................
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A0A6P7Y1K8_9AMPH/395-529 ..............................................EGKNPLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIN...ELK.KKEKALQEALLEKVEELKKIC..LR...EA..............EL........T.GQLPAE..Y..P..LGS.GE....K.....P..PQFRRR..I.GT..S..FK....LDS-NLL.Q.N.............................E.EN.P..YLQNLE.SKFIIQQKMVEAAKKLASEPDLSKN......................................................
A0A4W3HHM8_CALMI/384-518 ............................................dg--KNPLITTSN.GSLIS.........S.......G............S..Q.D.S.E..V..S..D.E.....Q...K......K.E.KLI...ELK.QRQSTLQEILGQKMEELKKIC..LR...EA..............EL........T.GKLPKE..Y..P..QTT.GE....E.....P..PHIRRR..V.GT..A..FK....LDD-NLL.Q.T.............................E.ED.P..YLQDVE.NKFVIQQKIVEAARKLANDPDICKN......................................................
A0A3Q1G5A6_9TELE/341-474 .............................................g-LKNNFITASN.GSLVS.........T.......G............S..A.D.S.E..M..S..E.E.....Q...K......K.E.KLS...ELR.KKEQEIQDILAKKTKELKKIC..LR...EA..............EL........T.GKLPKE..Y..P..LSS.GE....R.....P..PQVRRR..V.GT..A..FK....LDD--LF.P.Y.............................N.ED.P..FLRNLE.SRFALQQKIVEAAKKLANEPELCKT......................................................
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A0A1S3KPV1_SALSA/364-499 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLKQRLEELKNIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GP..A..FK....LDEHKIK.P.K.............................R.EE.E..ELERLE.REFAIQSQITEAARRLAGDPHGS--sk....................................................
A0A3Q2WBG1_HAPBU/181-314 ..............................................ESKNHLIMASN.GSLIS.........T.......G............S..A.D.S.E..V..S..E.E.....Q...K......K.E.KIA...ELK.KKEKELQDKLSAKLEELKKIC..LR...EA..............EL........T.GRLPKE..Y..P..LAT.GE....K.....V..PQVRRR..V.GT..A..FK....LDD--LF.P.Y.............................D.ED.P..HLRNLE.SRFALQQKIVEAAMKLANEADLCKT......................................................
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A0A665V0D4_ECHNA/373-509 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLRQRLEELKSIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.E..ELERLE.REFAIQSQITEAARRLASDPHVN--skk...................................................
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A0A7L1RSG8_9PASS/320-455 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A1S3MFN8_SALSA/342-475 .............................................n-LKHNLIMAST.GSLAS.........T.......G............S..A.D.S.A..V..D..E.E.....Q...R......K.E.KIS...ELK.KKEQEIQDVLTQKTKELKKIC..LL...EA..............EL........T.GKLPKE..Y..P..LFA.GE....R.....P..PHVRRR..V.GT..T..FK....LDD--LF.P.Y.............................N.ED.P..YLRNLE.SRFALQQKIVEAAKKLASEAELCKT......................................................
A0A8C5YVI9_MARMA/395-529 ..............................................EAKGQFIMASN.GSLIS.........S.......G............S..Q.D.S.E..A..S..E.E.....Q...K......R.E.KIL...ELR.RKEKQLQEKLLKKVEELRKIC..LR...EA..............EL........T.GKVPKE..Y..P..LNA.GE....K.....P..PQVRRR..V.GT..A..FK....LED-SLL.P.S.............................E.EG.P..ALQGLE.SNFLIQQKLVEAAKKLANEPDLCKT......................................................
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A0A2P4SAK4_BAMTH/2-128 .............................................e-GREEAGDSDS.GIMLH.........S.......G............P..S.S.P.T..A..P..L.K.....E...-......-.-.---...-LA.QRVRRQQQALELCVQELRRLC..LR...EA..............EL........T.GTLPQE..F..P..LKA.GE....K.....P..PKVRRR..I.GA..A..FK....LDES-LV.L.R.............................G.AD.P..-LGALE.RDLALQMQIARAAHRLCREENISKQ......................................................
A0A669BKH0_ORENI/181-314 ..............................................ESKNHLIMASN.GSLIS.........T.......G............S..A.D.S.E..V..S..E.E.....Q...K......K.E.KLA...ELK.KKEKELQDKLSAKLEELKKIC..LR...EA..............EL........T.GRLPKE..Y..P..LAT.GE....K.....V..PQVRRR..V.GT..A..FK....LDD--LF.P.Y.............................D.ED.P..HLRNLE.SRFALQQKIVEAAMKLANEADLCKT......................................................
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A0A6P7IPF4_9TELE/2-137 .............................................e-GNGEISDTDS.GIILH.........S.......G............S..D.S.P.T..T..H..T.K.....D...V......T.T.HTR...AMK.LKHQALQDRLEICILELKKLC..IR...EA..............QL........T.GRLSED..Y..P..LLP.GE....K.....P..PQVRRR..I.GA..A..FK....LDEQNIH.R.R.............................A.ED.S..KMNLVD.AELALQSKIYEAARKLCKEEHLSK-a.....................................................
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A0A3Q3M7K9_9LABR/364-499 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLKKRLEELKSIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....A..PTVRRK..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.E..ELERLE.REFAIQSQITEAARRLASDPHVSS-k.....................................................
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A0A0V1I109_9BILA/411-550 ......................................nstsdlgs--------SVS.SQSLR.........S.......L............P..N.M.C.Y..A..D..E.E.....Q...Ar....dS.E.FYK...QLQ.SRKQALELLLIEKLKELKDVC..IQ...EG..............NI........T.GEIPSE..LysA..LAP.GE....A.....E..PKIKRR..V.GT..S..FS....ISPDLVN.K.L.............................V.TI.D..HISKLE.ADVEIKRKIVAGHEKLVNDPSVS--sv....................................................
A0A3Q2HSN1_HORSE/394-529 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPVE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKVL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A6J3QMD5_TURTR/2-131 ..............................................ESKDEVSDTDS.GIILQ.........S.......G............P..D.S.P.V..A..P..A.K.....-...-......-.E.LTH...AVR.KQQRALEARLEACLEELRRIC..LR...EA..............EL........T.GILPAE..Y..P..FRP.GE....K.....A..PKVRRR..I.GA..A..YK....LDEWALH.-.-.............................R.ED.P..-LSSLE.RELALQLQIAEAARRLCREGNLGR-q.....................................................
A0A3B5QCJ4_XIPMA/364-499 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLRQRLEELKSIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.E..ELERLE.REFAIQSQITEAARRLASDPHVSS-k.....................................................
A0A6J1V5J8_9SAUR/395-529 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIL...ELR.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LNT.GE....K.....P..PQVRRR..V.GT..T..FR....LDD-NLL.P.N.............................E.ED.P..TLQNLE.SNFLIQQKFVEAAKKLAGEPDLCKN......................................................
A0A6Q2WRC2_ESOLU/343-476 .............................................n-LKNNLIMAST.GSLVS.........T.......G............S..A.D.S.V..V..D..E.E.....Q...K......K.E.KIS...ELK.KKEQEIQDVLTQKTKELKKIC..LR...EA..............EL........T.GKLPKE..Y..P..LST.GE....R.....P..PHVRRR..V.GT..A..FK....LDD--LF.P.Y.............................N.ED.P..YLRNLE.SMFALQQKIVEAAKKLASESELCKT......................................................
W2SHC9_NECAM/80-212 .........................dgscanlptlknglrqksged-----------.-----.........-.......-............-..-.-.-.-..-..-..R.Q.....R...D......I.E.LYK...VLR.GRKAELEELLRTRINELRSIC..LR...EG..............EI........T.GEMPEE..IktT..LRP.GE....E.....M..PKLKKR..V.GT..S..FS....IPEE-IL.K.C.............................D.KA.D..KISQLE.TDVELHKKIVAAAERLAKDKTMNK-s.....................................................
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A0A0V1I0N1_9BILA/411-550 ......................................nstsdlgs--------SVS.SQSLR.........S.......L............P..N.M.C.Y..A..D..E.E.....Q...Ar....dS.E.FYK...QLQ.SRKQALELLLIEKLKELKDVC..IQ...EG..............NI........T.GEIPSE..LysA..LAP.GE....A.....E..PKIKRR..V.GT..S..FS....ISPDLVN.K.L.............................V.TI.D..HISKLE.ADVEIKRKIVAGHEKLVNDPSVS--sv....................................................
A0A3Q4A966_MOLML/2-135 .............................................e-GNGEISDTDS.GIILH.........S.......G............S..D.S.P.T..T..V..T.K.....D...V......T.T.HTR...AMK.LKHQDLKDKLEICLLELKKLC..IR...EA..............EL........T.GRLSED..Y..P..LLP.GE....K.....P..PQIRRR..I.GT..A..FK....LDEQSIP.Q.-.............................-.GE.S..ELSLVD.AELALQMKIFEAARKLCREDHLNK-a.....................................................
A0A8B7V7X3_CASCN/349-483 ..............................................EAKSQFIMASN.GSLVS.........S.......G............S..Q.D.S.E..A..S..E.E.....Q...K......R.E.KIL...ELK.KKEKLLQEKLLRKVEELKKIC..LR...EA..............EL........T.GRMPKE..Y..P..LNI.GE....K.....P..PQVRRR..V.GP..R..SK....LDD-NLL.P.S.............................E.ED.P..TLQDLE.SNFLIQQKLVEAAKKLANEPDLCKT......................................................
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A0A6I9PXS4_9TELE/373-508 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEDTLKKRLEELKNIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GT..A..FK....LDEQKIT.L.K.............................G.EE.E..ELERLE.REFAIQSQITEAARRLASDPHVSS-k.....................................................
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A0A8C5H1M8_9TELE/353-488 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLKQRLEELKSIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.E..ELERLE.REFAIQSQITEAARRLASDPHVSS-k.....................................................
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A0A3Q1HUQ1_ANATE/390-523 .............................................g-SKDQLIMASN.GSLIS.........A.......G............S..A.D.S.E..V..S..E.E.....Q...K......K.E.KIA...ELK.KKEKDLQDTLTKKLEELKKIC..MR...EA..............EL........T.GRMPKE..Y..P..LAT.GE....K.....A..PQVRRR..V.GT..A..FK....LDD--LF.P.Y.............................D.ED.P..HLGNLE.SKFALQQKIVEAAMKLAKEGDLCKT......................................................
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A0A6J3DHN2_AYTFU/341-475 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELK.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LSA.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.T.............................E.ED.P..ALQELE.SNFIIQQKLVEAAKKLASEPDLCKN......................................................
A0A6Q2Z827_ESOLU/347-480 .............................................n-LKNNLIMAST.GSLVS.........T.......G............S..A.D.S.V..V..D..E.E.....Q...K......K.E.KIS...ELK.KKEQEIQDVLTQKTKELKKIC..LR...EA..............EL........T.GKLPKE..Y..P..LST.GE....R.....P..PHVRRR..V.GT..A..FK....LDD--LF.P.Y.............................N.ED.P..YLRNLE.SMFALQQKIVEAAKKLASESELCKT......................................................
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A0A3P8Y4T4_ESOLU/37-172 ............................................ih--REEISDTDS.GIMLN.........S.......G............P..D.S.P.M..S..Q..G.K.....D...L......N.T.HTR...AMR.LRHQALEERLELCMLELRKLC..IR...EA..............EL........T.GKLSSD..F..P..LLP.DE....K.....P..PRIRRR..I.GA..T..FK....LDDSLIH.Q.D.............................G.ED.S..ELHSLE.ADLALQLQIFEAARRLSVEEHLSK-p.....................................................
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A0A8C8H8R1_ONCTS/328-460 ..............................................ESKDQLIMASN.GSLIS.........A.......G............S..A.D.S.E..V..S..E.E.....Q...K......-.K.KVA...DLK.KKQQDLQDSLTQKLEELKKIC..LR...EA..............EL........T.GSLPKE..Y..P..LAS.GE....K.....P..PVVRRR..M.GT..A..FK....LDD--LF.P.Y.............................D.AD.P..HLRNLE.SRFALQQKIAEAAKKLANEAELCKT......................................................
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A0A8M9Q755_DANRE/395-528 ..............................................ESKDKLIMASN.GSLVS.........S.......N............S..A.D.N.D..V..N..E.E.....Q...K......K.E.KIA...ELK.DKQEKIKQILALKEEELKKMC..LR...EA..............EL........T.GVLPKE..F..P..LAS.GE....K.....P..PTIRRR..V.GT..A..FK....LDD--LF.P.Y.............................D.AD.P..CLRNLE.SCFALQKKIVEAARKLAHENELGK-t.....................................................
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A0A7F8KBC5_DELLE/2-144 ..............................................EVKGQLISSPT.FSASA.........A.......L............F..G.E.A.A..P..Q..V.K.....-...-......S.E.RLR...GLL.DRQRTLQEALSLKLQELRKVC..LQ...EA..............EL........T.GQLPPE..C..P..LEP.GE....R.....P..QLVRRR..P.PA..A..RA....YPPPHPN.P.Ahhsl....................cpakaP.QE.L..ALEALE.REVSVQQQIAAAARRLALAPELSA-e.....................................................
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A0A6P6CUK5_PTEVA/2-123 ..............................................ESKDDVSSTDS.GIILQ.........S.......G............P..D.S.P.V..S..P..L.K.....E...L......K.E.VTQltyAIR.RQQRALEGRLEACLEELRALC..LR...EA..............EL........T.GVLPAE..Y..P..LKP.GE....K.....A..PKVRRR..V.GA..A..YR....LDEQALS.K.E.............................V.R-.-..------.-------------------------nlspqrrplsrdlasa......................................
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A0A672QHY0_SINGR/47-180 ..............................................ESKDKLIMASN.GSLVS.........S.......N............S..G.D.N.E..V..N..D.E.....Q...K......K.E.KIA...ELK.NKQESIKEILALKEEELKKIC..LR...EA..............EL........T.GVLPKE..Y..P..LAP.GE....K.....P..PTVRRR..V.GT..A..FK....LDD--LF.P.Y.............................D.AD.P..HLRNLE.SCFALQKKIVEAAKKLAYENELCKT......................................................
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A0A8V0XN91_CHICK/47-182 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
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A0A2K5ENP8_AOTNA/395-529 ..............................................EAKSQFIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......R.E.KIL...ELK.KKEKLLQEKLLKKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LNI.GE....K.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..TLQELE.SNFLIQQKLVEAAKKLASEPDLCKT......................................................
A0A7J6BPV1_9TELE/340-473 .............................................g-VKNQLIMASN.GSLVS.........T.......G............S..A.D.S.E..M..N..D.D.....Q...K......K.E.KLA...ELR.KKEREIQDILGQKLTELKEIC..LR...EA..............QL........T.GKLPKE..Y..P..LIK.GE....T.....P..PHVRRR..V.GT..A..FK....LDD--LF.P.Y.............................N.ED.P..YLRNLE.SRFALQQKIVEAAKKLAAEPDISK-l.....................................................
A0A7L0ZBR2_9PASS/323-458 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A8V0ZJE2_CHICK/341-475 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELK.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LSA.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.T.............................E.ED.P..ALQELE.SNFVIQQKLVEAAKKLASEPDLCKN......................................................
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A0A7L3C9E2_PELUR/101-235 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELK.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LSA.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..ALQDLE.SNFIIQQKLVEAAKKLASEPDLCKN......................................................
A0A0V1I0U2_9BILA/411-550 ......................................nstsdlgs--------SVS.SQSLR.........S.......L............P..N.M.C.Y..A..D..E.E.....Q...Ar....dS.E.FYK...QLQ.SRKQALELLLIEKLKELKDVC..IQ...EG..............NI........T.GEIPSE..LysA..LAP.GE....A.....E..PKIKRR..V.GT..S..FS....ISPDLVN.K.L.............................V.TI.D..HISKLE.ADVEIKRKIVAGHEKLVNDPSVS--sv....................................................
A0A7K5P1P8_CHRMC/1-36 ..............................................-----------.-----.........-.......-............-..-.-.-.-..-..-..-.-.....-...-......-.-.---...---.---------------------..--...--..............--........-.------..-..-..LKA.GE....K.....P..PKVRRR..I.GA..A..FK....LDETLVL.R.-.............................-.--.-..------.-------------------------gavrgspgl.............................................
A0A0V0SDG5_9BILA/393-532 ......................................nstsdlgs--------SVS.SQSLR.........S.......L............P..N.M.C.Y..A..D..E.E.....Q...Ar....dS.E.FYK...QLQ.SRKQALELLLIEKLKELKDVC..IQ...EG..............NI........T.GEIPSE..LysA..LAP.GE....A.....E..PKIKRR..V.GT..S..FS....ISPDLVN.K.L.............................V.TI.D..HISKLE.ADVEIKRKIVAGHEKLVNDPSVS--sv....................................................
A0A7K4VZP5_9TYRA/101-235 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELK.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LSA.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..TLQDLE.SNFIIHQKLVEAAKKLASEPDLCKN......................................................
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A0A6G0IMH6_LARCR/39-147 ...................................etqamevkgql-----------.---I-.........S.......A............P..D.P.L.T..C..L..D.R.....K...Q......R.E.RMA...ELQ.ERRRSLQALLSTRLAELRRIC..LQ...EA..............EL........T.GAVPSD..F..P..LEV.GE....K.....L..PCVQRR..G.GT..S..RQ....TNR-KCR.A.E.............................E.ED.S..Q-----.-------------------------rskpkktl..............................................
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A0A7L4A1M2_9AVES/1-122 ................................gpdspvsplkeggg-----------.-----.........-.......-............-..-.-.-.-..-..-..-.-.....-...-......-.-.---...GGR.RQQQALEARLEGWGGGLRRLC..LR...EA..............VMspcrgggvT.GTLPRE..Y..P..LKA.GE....G.....G..GGVRRR..I.GA..A..FK....LDET-RG.G.G.............................G.AD.P..-LSALE.RDLALGGGGAKAARRLCREENISR-g.....................................................
A0A7K8MML2_9CORV/2-110 ...........................................rgm---GEASDTDS.GIMLH.........S.......G............P..N.S.P.V..S..L..P.K.....-...-......-.E.RVQ...AGR.RQQQALEARLDGCVQELRRLC..LR...EA..............EL........T.GTLPRE..Y..P..LKA.GE....K.....P..PKVRRR..I.GA..A..FK....LDEIVVL.-.-.............................-.--.-..------.-------------------------rgvvrrvplvcsl.........................................
A0A2K6BBD0_MACNE/357-492 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPVE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A8C5RQR2_LATLA/2-133 ..............................................EVKGQLINSSS.YSSSE.........A.......L............Q..R.E.L.C..P..R..I.R.....-...-......L.E.RVQ...ELL.EKQKSLQQVLSLRLKELRRVC..LQ...EA..............EL........T.GKLPPE..Y..P..LEP.GE....R.....L..WPVRRR..T.TV..A..SR....IAP--VL.K.N.............................E.EN.P..SLEELS.QELALQQQVAEAARRLAVAPDLT--vd....................................................
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A0A3Q2FD80_CYPVA/5-108 ...................................gqlilapeplt-----------.-----.........-.......-............-..-.-.-.-..C..P..N.R.....K...Q......K.A.RMA...ELQ.ERRRSLQALLSTRLAELRRIC..LQ...EA..............EL........T.GAVPTD..F..P..LEA.GE....K.....P..PCFRRR..G.GT..S..RQ....GNRKCRV.E.-.............................E.EE.S..------.-------------------------qrsksrktlfsa..........................................
A0A7K8PFB1_COCCO/101-235 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELK.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LSA.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..ALQDLE.SNFIIQQKLVEAAKKLASEPDLCKN......................................................
A0A7K5ZMU3_ONYCO/101-235 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELK.RKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LSA.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..TLQDLE.SNFIIHQKLMEAAKKLASEPDLCKN......................................................
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A0A8C8BNI2_9STRI/395-529 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELK.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LST.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..TLQELE.SNFIIQQKLVEAAKKLASEPDLCKN......................................................
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A0A6J2GS64_9PASS/352-487 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A851TZR2_9PASS/317-452 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
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A0A852FVQ8_PEUTA/320-455 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A6P9DL32_PANGU/395-529 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIL...ELR.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LNT.GE....K.....P..PQVRRR..V.GT..T..FR....LDD-NLL.P.N.............................E.ED.P..TLQNLE.SNFLIQQKMVEAAKKLAGEPDLCKN......................................................
A0A7L3I1T8_9PASS/77-212 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A1S3MIH9_SALSA/12-126 ......................................dllggspe-----------.-----.........-.......-............-..-.-.-.-..-..-..-.-.....-...A......V.E.RMT...ELQ.DRRRSLETLLNSRLAELRRVC..LQ...EA..............EL........T.GELPGD..F..P..LEA.GE....R.....R..PNVRRR..V.GP..N..RH....GPKTIIK.T.E.............................-.EE.-..------.-------------------------vcrrkpkktlfigalrrrvecdqqpthskrtv......................
A0A667ZR68_9TELE/104-177 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLRQRLEELKSIC..IR...EA..............--........-.------..-..-..---.--....-.....-..------..-.--..-..--....-------.-.-.............................-.--.-..------.-------------------------vrqctqtyrqvy..........................................
A0A7L1ZWB4_LEILU/1-111 ......................................gpdslvsp-----------.-----.........-.......-............-..-.-.-.-..-..-..-.-.....-...P......K.E.QVQ...AGR.QQQQVLEARLDGCIQELRRLC..LR...EA..............EL........T.GTLPRE..Y..P..LKA.GE....K.....P..PKVRRR..I.GA..A..FK....LDEIVIL.R.-.............................G.VD.P..----LE.RERALQLQIAEASRRLCREENIGR-q.....................................................
A0A6J3F375_SAPAP/389-524 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPVE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A3P9CWN4_9CICH/373-508 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLKQRLEELKSIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.E..ELERLE.REFAIQSQITEAARRLASDPHVSS-k.....................................................
A0A6P8TUW8_GYMAC/2-108 .........................evkghlitsmglgapdvqgcq-----------.-----.........-.......-............-..-.-.-.-..-..D..S.K.....L...Q......A.E.RVA...ALQ.ERKQALEALLSSREGELKHVC..LQ...EA..............EL........T.GKISHA..F..P..LET.GE....K.....P..PVVQRR..A.GLppN..TK....AED----.-.-.............................-.--.-..------.-------------------------eaaqrkqmkaift.........................................
A0A7J8AZY8_PIPKU/372-507 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPVE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A2K6M5M2_RHIBE/363-510 .............................................g-SKGKIISGSS.GSLLS.........S.......GsgarrhcillpgS..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPVE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A3Q7MTF2_CALUR/101-230 ..............................................ESKDEVSDTDS.GIILQ.........S.......G............P..D.S.P.V..S..P..V.K.....-...-......-.E.LTH...AVR.KQQRALEERLEACLEELKRLC..LR...EA..............EL........T.GVLPAE..Y..P..LKP.GE....K.....A..PKVRRR..I.GA..A..YK....LDERALR.-.-.............................R.ED.P..-LSSLE.RELALQLQIAEAARRLCREENLGR-q.....................................................
A0A6P6KXP8_CARAU/2-137 ..............................................EGKEEISDTDS.GVILH.........S.......G............P..D.S.P.A..T..V..M.K.....D...V......N.T.HTR...VMK.LKQQALEDRLKMCLLELKKLC..IR...EA..............EL........T.GHLSSD..Y..P..LSP.AE....K.....P..PQIRRR..I.GA..S..FK....LDEPSIL.H.K.............................T.ED.S..ELSSVE.ADLALQQQIYVAAQRLCQEEHLSK-a.....................................................
A0A226NKS2_CALSU/395-529 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELK.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LSA.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.T.............................E.ED.P..ALQELE.SNFIIQQKLVEAAKKLASEPDLCKN......................................................
A0A670JJK4_PODMU/395-529 ..............................................EAKSQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..A..S..E.E.....Q...K......K.E.KIL...ELK.KKEKFLQEKLLQKVDELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LGT.GE....K.....P..PQVRRR..V.GT..A..FK....LDG-NLL.P.S.............................E.ED.P..ALQNLE.SNFFIQQKMVEAVKKLSSEPDLCKN......................................................
A0A7K9Q9I1_IRECY/1-127 ............................................gm---GEASDMDS.GTMLH.........S.......G............S..D.S.P.V..S..P..S.K.....-...-......-.E.RVQ...AGQ.RQQQALEAQLDCCIQELRRLC..LR...EA..............EL........T.GTLPCE..Y..P..LKA.GE....K.....P..PKVHRR..I.GA..A..FK....LDEIAIL.R.-.............................G.VD.P..----LE.RERALQLQIAEASRRLCHEENIGR-q.....................................................
A0A851PNB8_ANHAN/324-459 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A3P9AGA0_ESOLU/236-369 .............................................n-LKNNLIMAST.GSLVS.........T.......G............S..A.D.S.V..V..D..E.E.....Q...K......K.E.KIS...ELK.KKEQEIQDVLTQKTKELKKIC..LR...EA..............EL........T.GKLPKE..Y..P..LST.GE....R.....P..PHVRRR..V.GT..A..FK....LDD--LF.P.Y.............................N.ED.P..YLRNLE.SMFALQQKIVEAAKKLASESELCKT......................................................
A0A3P8SZ59_AMPPE/342-477 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLRQRLEELKSIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.E..ELERLE.REFAIQSQITEAARRLASDPHVSS-k.....................................................
A0A674NKV3_TAKRU/194-327 ............................................cl--KNNLITASN.GSLVS.........T.......G............S..A.D.S.E..M..S..E.E.....Q...K......K.E.KLS...ELR.KKEQEIRDILTKKTKELKKIC..MR...EA..............EL........T.GKLPKE..Y..P..LSS.GE....R.....P..PQIRRR..V.GT..S..FK....LDD--LF.P.Y.............................N.ED.P..FLRNLE.SRFALQRKIVEAAKKLANEPELCKT......................................................
A0A0V1KPG3_9BILA/391-530 ......................................nstsdlgs--------SVS.SQSLR.........S.......L............P..N.M.C.Y..A..D..E.E.....Q...Ar....dS.E.FYK...QLQ.SRKQALELLLIEKLKELKDVC..IQ...EG..............NI........T.GEIPSE..LysA..LAP.GE....A.....E..PKIKRR..V.GT..S..FS....ISPDLVN.K.L.............................V.TI.D..HISKLE.ADVEIKRKIVAGHEKLVNDPSVS--sv....................................................
A0A091L4H8_9GRUI/230-364 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIT...ELK.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LSA.GE....E.....P..PQIRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..ALQDLE.SNFIIQQKLVEAAKKLASEPDLCKN......................................................
A0A8J4WYB6_CLAMG/173-309 .............................................d-CKEEISDSDS.GIMLN.........S.......G............P..D.S.P.T..S..P..V.K.....D...L......N.T.HTR...AMR.LKQQALEDRLELCLRELKKLC..IR...EA..............EL........T.GKLSPD..Y..P..LLP.NE....K.....P..PQIRRR..I.GA..S..FK....LDEGLLP.H.G............................dG.EE.S..ELHSLE.ADLALQRQIYEAARRLSLEENISK-p.....................................................
A0A6J3S2K8_TURTR/209-343 ..............................................EAKSQFIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......R.E.KIL...ELK.KKEKLLQEKLLKKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LNI.GE....K.....P..PHVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..ALQELE.SNFLIQQKLVEAAKKLASEPDLCKT......................................................
A0A6P3J0N4_BISBI/394-529 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPVE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A8M9P9D0_DANRE/341-474 ..............................................ESKDKLIMASN.GSLVS.........S.......N............S..A.D.N.D..V..N..E.E.....Q...K......K.E.KIA...ELK.DKQEKIKQILALKEEELKKMC..LR...EA..............EL........T.GVLPKE..F..P..LAS.GE....K.....P..PTIRRR..V.GT..A..FK....LDD--LF.P.Y.............................D.AD.P..CLRNLE.SCFALQKKIVEAARKLAHENELGK-t.....................................................
A0A6F9BJJ3_9TELE/372-499 ........................................yiysvn-----------.-NVTT.........T.......G............S..A.D.S.A..V..D..E.E.....Q...K......K.E.KIS...ELK.KKEQEIQDVLTQKTKELKKIC..LR...EA..............EL........T.GKLPKE..Y..P..LSA.GE....R.....P..PQVRRR..V.GT..A..FK....LDD--LF.P.Y.............................N.ED.P..YLRNLE.SRFALQQKIVEAAKKLASEAELCKT......................................................
A0A3M0LAU9_HIRRU/7-74 ............................................ad-----------.-----.........-.......-............-..-.-.-.-..-..-..-.-.....-...-......-.-.---...---.---------------------..--...--..............--........-.GAVAPE..Y..P..LEP.GE....R.....P..QPPPRR..R.SA..G..PR....GDPP---.-.-.............................R.GV.P..CRREAQ.RQVQVQLQVLEAARRLAAVPG----lppe..................................................
A0A8B7Z085_ACAPL/202-331 ............................kdakeassrellaiegev-----------.-----.........-.......-............-..-.-.-.-..-..-..-.-.....A...R......K.E.LVE...ALK.ARKVVLQDTLQEKLENLRQLC..LK...EA..............EI........T.GELPIE..Y..P..RIP.GE....P.....L..PRPKTR..V.TT..A..FT....LSDKTVN.T.Pe..........................shE.ED.E..GLSRLE.GEYEIQSKITTAAMKLANDPTISKK......................................................
A0A8C4H2R5_DICLA/341-474 .............................................g-LKNNLITASN.GSLVS.........T.......G............S..A.D.S.E..M..S..E.E.....Q...K......K.E.KLS...ELR.KKEQEIQDILAKKTKELKKIC..LR...EA..............EL........T.GKLPKE..Y..P..LSS.GE....R.....P..PHVRRR..V.GT..A..FK....LDD--LF.P.Y.............................N.ED.P..FLRNLE.SRFALQQKIVEAAKKLANEPELCKT......................................................
G0PFU3_CAEBE/106-230 ......................................dlnetlhn-----------.-----.........-.......-............-..-.K.S.A..D..E..F.Q.....K...D......L.E.KYE...FLK.TRKADLEARLRQKMQELKAVC..IE...EG..............DI........T.GEMPVE..I..NdvVLP.GD....D.....F..PRLKRR..V.GT..A..YS....IPDELIK.A.-.............................D.KA.D..KMSQLE.TDVELHRRIVAAASRLATDKNTNK-s.....................................................
A0A4X2KE76_VOMUR/47-181 ..............................................EAKNQFIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELR.KKEKLLQEKLLKKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LNS.GE....K.....P..PQVRRR..I.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..ALQELE.SNFVIQQKLVEAAKKLAHEPDLCKN......................................................
A0A8J4NV53_EUDCH/101-235 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELK.KKETLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LSA.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..ALQDLE.SNFIIQQKLVEAAKKLASEPDLCKN......................................................
A0A2T7NU36_POMCA/378-515 .........................srsassqslpslggsrfdlnm-----------.-----.........-.......-............-..-.E.N.L..E..S..Q.K.....A...E......R.E.MFK...ALK.ARKEALEEALRSKLEELKLLC..FQ...EG..............EL........T.GELPKE..T..P..LEA.GE....R.....V..PTFRRR..I.GT..S..FA....LSPKTIH.K.K............................dQ.NE.D..HLATLE.LEYELQSKITSAAHSLAHDKSVSK-y.....................................................
A0A8C5HWY0_9TELE/395-528 ..............................................ESKDHLIRASN.GSLIS.........A.......D............S..A.E.S.E..V..N..E.E.....Q...K......K.E.KIA...ELK.KKEKDLQDSLTKKLEELKKIC..MR...EA..............EL........T.GRLPKE..Y..P..LAT.GE....K.....A..PPVRRR..V.GT..A..FK....LED--LF.P.Y.............................D.ED.P..HLRNLE.SRFALQQKIVEAAMKLANEGDLCKT......................................................
A0A5F8GRU1_MONDO/2-132 ..............................................EVRGQLISSPS.YNCP-.........A.......L............P..L.E.E.T..P..P..A.K.....-...-......V.E.RLR...VLL.ERQRGLQETLTLKLRELRRVC..LL...EA..............EL........T.GRLPAE..Y..P..LEP.GE....Q.....P..HPIRRR..A.AP..-..VP....LPPWGLC.P.-.............................S.GV.L..ALESLE.REVSVQRQIATAARRLALAPELSL-e.....................................................
A0A3Q3FGX2_9LABR/5-140 ..............................................ESKEEISDTDS.GIILH.........S.......G............P..D.S.P.I..S..P..V.K.....D...L......T.T.NTR...ALK.LKHQSLEERLELCLLELRKLC..IR...EA..............EL........T.GKLPSD..Y..P..LMP.DE....K.....P..PRVRRR..I.GA..S..FK....LDEGLIH.L.N.............................N.QD.S..ELQALE.TDLALQRQIYEAVRKLSVEEKLSK-p.....................................................
A0A8C7L9D7_ONCKI/328-460 ..............................................ESKDQLIMASN.GSLIS.........A.......G............S..A.D.S.E..V..S..E.E.....Q...K......-.K.KVA...DLK.KKRQDLQDSLTQKLEELKKIC..LR...EA..............EL........T.GSLPKE..Y..P..LAS.GE....K.....P..PVVRRR..M.GT..A..FK....LDD--LF.P.Y.............................D.AD.P..HLRNLE.SRFALQQKIVEAAMKLANEAELCKT......................................................
K7GLI6_PIG/2-130 ..........................................evka-----------.-----.........A.......L............F..G.E.A.A..P..Q..V.K.....-...-......S.E.RLR...GLL.DRQRALQEALSLKLQELRKVC..LQ...EA..............EL........T.GQLPPE..C..P..LEP.GE....R.....P..QLVRRR..P.PA..A..RA....YPPPPHP.-.Npaqh.....................slcpA.EE.L..ALEALE.REVSVQQQIAAAARRLALAPELST-e.....................................................
A0A8M9PYT3_DANRE/395-528 ..............................................ESKDKLIMASN.GSLVS.........S.......N............S..A.D.N.D..V..N..E.E.....Q...K......K.E.KIA...ELK.DKQEKIKQILALKEEELKKMC..LR...EA..............EL........T.GVLPKE..F..P..LAS.GE....K.....P..PTIRRR..V.GT..A..FK....LDD--LF.P.Y.............................D.AD.P..CLRNLE.SCFALQKKIVEAARKLAHENELGK-t.....................................................
A0A8C3FD55_CHRPI/363-498 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
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G3PG98_GASAC/342-477 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQDALEETLKKRLEELKSIC..IR...EA..............EL........T.GRLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GT..A..FK....LDEQKIH.P.K.............................G.EE.E..ELERLE.REFAIQSQITEAARRLASDPHVSS-k.....................................................
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A0A821W7F7_9NEOP/3-85 ......................................tstmgsdl-----------.-----.........-.......-............-..-.-.-.-..-..-..H.S.....D...K......Q.D.KLL...KLQ.ARKKELEQMLAAKNEELYKLC..VQ...EV..............QL........T.GIMPPE..A..P..LSP.EV....P.....-..------..-.--..-..--....-------.-.-.............................-.--.-..------.-------------------------qrerlgsirsvdrstdgtdvq.................................
A0A8B6ZUD8_ORYAF/101-230 ..............................................ESKDEVSDTDS.GIILQ.........S.......G............P..D.S.P.I..S..P..M.K.....K...L......-.-.-TH...AVR.KQQRALEERLEACLEELRRIC..LR...EA..............EL........T.GILPAE..Y..P..LKP.GE....K.....A..PKVRRR..I.GA..A..YK....LDERALH.R.-.............................-.ED.P..-MSSLE.QELALQLQITEAARQLCREENISRQ......................................................
A0A668SPN6_OREAU/289-422 ..............................................ESKNHLIMASN.GSLIS.........T.......G............S..A.D.S.E..V..S..E.E.....Q...K......K.E.KLA...ELK.KKEKELQDKLSAKLEELKKIC..LR...EA..............EL........T.GRLPKE..Y..P..LAT.GE....K.....V..PQVRRR..V.GT..A..FK....LDD--LF.P.Y.............................D.ED.P..HLRNLE.SRFALQQKIVEAAMKLANEADLCKT......................................................
A0A7L3D6G7_PLUSO/101-235 ..............................................EAKNQLIMASN.GSLVS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELK.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LGA.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..TLQDLE.SNFIIQQKLVEAAKKLASEPDLCKN......................................................
A0A315V9V4_GAMAF/189-287 ..............................amevkgqlilapeplt-----------.-----.........-.......-............-..-.-.-.-..C..P..S.R.....K...Q......K.E.RMA...ELQ.ERRRSLQVLLSARLAELRRIC..LQ...EA..............EL........T.GAVPSN..F..P..LEA.GE....K.....P..PCVRRR..A.AP..T..RQ....GNR-KCR.A.E.............................E.E-.-..------.-------------------------dghr..................................................
A0A452EQP0_CAPHI/395-529 ..............................................EAKSQFIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......R.E.KIL...ELK.KKEKLLQEKLLKKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LNV.GE....K.....P..PQVRRR..I.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..ALQELE.SNFLIQQKLVEAVKKLASEPDLCKT......................................................
A0A673FTC1_9TELE/47-209 ..............................................ESKDKLIMASN.GSLVS.........S.......N............S..G.D.N.E..V..N..E.E.....Q...K......K.E.KIA...ELK.NKQESIKEILALKEEELKKIC..LR...EA..............EL........T.GVLPKE..Y..P..LAP.GE....K.....P..PTVRRR..V.GT..A..FK....LDD--LF.P.YdavgclncfsqklcknclilctlliqlfsL.QD.P..HLRNLE.SCFALQKKIVEAAKKLAYENELCKT......................................................
A0A7L4D8K9_9AVES/328-463 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A8B9F888_9PSIT/359-494 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
G1KYA4_ANOCA/4-135 .............................................r-SKDETSDTDS.GIIVQ.........S.......G............L..D.S.P.M..A..P..M.K.....D...L......-.-.-TQ...AMR.KQQKALEEKLEACVQELRRLC..LR...EA..............EL........T.GLLPSE..Y..P..VKP.GE....K.....P..PKVRRR..V.GA..A..FR....LDEKAIL.S.R.............................G.AD.P..-LSTLE.RDLALQLQIAEASRCLSREENLTKQ......................................................
A0A5F9CVP5_RABIT/373-508 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPVE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A1S3KNZ1_SALSA/372-507 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLKQRLEELKNIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GP..A..FK....LDEHKIK.P.K.............................R.EE.E..ELERLE.REFAIQSQITEAARRLAGDPHGS--sk....................................................
A0A8M1GKU6_URSMA/87-216 ..............................................ESKDEVSDTDS.GIILQ.........S.......G............P..D.S.P.V..S..P..M.K.....-...-......-.E.LTH...AVR.KQQRALEERLEARLEELKRLC..LR...EA..............EL........T.GILPAE..Y..P..LKP.GE....K.....A..PKVRRR..I.GA..A..YK....LDERALH.R.-.............................-.ED.P..-LSSLE.QELALQLQIAEAARRLCREENLSRQ......................................................
A0A8C4N3D1_EPTBU/409-544 .............................................g-SESKLISGSD.GSLFS.........S.......G............S..Q.E.S.E..L..S..Q.E.....A...K......K.D.LMN...ALT.IRKETLEETLRLRQQELKQLC..LR...EA..............DL........T.GVLPRE..Y..P..LSA.GE....K.....T..PLVRRR..I.GT..S..FK....LDEQKLM.L.L.............................G.EE.A..ELERLE.RDFAIQSQITEAAKRLASDCSIGK-k.....................................................
A0A8C5HUY7_9TELE/395-528 ..............................................ESKDHLIRASN.GSLIS.........A.......D............S..A.E.S.E..V..N..E.E.....Q...K......K.E.KIA...ELK.KKEKDLQDSLTKKLEELKKIC..MR...EA..............EL........T.GRLPKE..Y..P..LAT.GE....K.....A..PPVRRR..V.GT..A..FK....LED--LF.P.Y.............................D.ED.P..HLRNLE.SRFALQQKIVEAAMKLANEGDLCKT......................................................
A0A3Q2HU00_HORSE/349-483 ..............................................EAKSQFIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......R.E.KIL...ELK.KKEKLLQEKLLKKVEELKKIC..LR...EA..............EL........T.GKIPKE..Y..P..LNI.GE....K.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..ALQELE.SNFLIQQKLVEAAKKLANEPDLCKT......................................................
A0A8C7KQG4_ONCKI/334-467 .............................................n-LKHNLIMAST.GSLAS.........T.......G............S..A.D.S.A..V..D..E.E.....Q...K......K.E.KIS...ELK.KKEQEIQDVLTQKTKELKKIC..LR...EA..............EL........T.GKLPKE..Y..P..LSA.GE....R.....P..PQVRRR..V.GT..A..FK....LDD--LF.P.Y.............................N.ED.P..YLRNLE.SRFALQRKIVEAAKKLASEAEICKT......................................................
A0A8M9QGB7_DANRE/395-528 ..............................................ESKDKLIMASN.GSLVS.........S.......N............S..A.D.N.D..V..N..E.E.....Q...K......K.E.KIA...ELK.DKQEKIKQILALKEEELKKMC..LR...EA..............EL........T.GVLPKE..F..P..LAS.GE....K.....P..PTIRRR..V.GT..A..FK....LDD--LF.P.Y.............................D.AD.P..CLRNLE.SCFALQKKIVEAARKLAHENELGK-t.....................................................
G3NGN3_GASAC/344-477 .............................................g-LKNNLITASN.GSLVS.........T.......G............S..A.D.S.E..I..S..E.E.....Q...K......K.E.KLS...ELR.KKEIELQDILAKKTKELKKIC..LR...EA..............EL........T.GKLPKE..Y..P..LSS.GE....R.....P..PQVRRR..V.GT..T..FK....LDD--LF.P.Y.............................N.ED.P..FLRNLE.SRFALQKKIVEAAKKLANEAELCKT......................................................
A0A094MD03_ANTCR/77-212 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A3Q2VAF6_HAPBU/353-488 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.T.....A...K......K.D.MLA...ALR.ARQEALEETLKQRLEELKSIC..IR...EA..............EL........T.GKLPKE..Y..P..LDP.GE....E.....P..PTVRRK..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.E..ELERLE.REFAIQSQITEAARRLASDPHVSS-k.....................................................
A0A850VT01_FREMA/320-455 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A6J2AKA4_ACIJB/2-131 ..............................................ESKDEVSDTDS.GIILQ.........S.......G............P..D.S.P.V..S..P..V.K.....-...-......-.E.LTH...AVR.KQQRALEERLEAHLEELKRLC..LR...EA..............EL........T.GVLPAE..Y..P..LKP.GE....K.....A..PKVRRR..I.GA..A..YK....LDERALH.R.-.............................-.ED.P..-LSGLE.QELALQLQIAEAARRLCREGNLSRQ......................................................
A0A1V4K0D9_PATFA/352-487 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A8B8Z371_BALMU/15-81 .............................................i-----------.-----.........-.......-............-..-.-.-.-..-..-..-.-.....-...-......-.-.---...---.---------------------..--...--..............--........-.--LQSE..Y..P..FRL.GE....K.....A..PKVRRR..I.GA..A..YK....LDEWALH.-.-.............................R.ED.P..-LSSLE.RELALQLQIAEAARRLCREGNLGR-q.....................................................
A0A437D7C3_ORYJA/141-274 .............................................g-LKNNFITASN.GSLVS.........T.......G............S..A.D.S.E..M..S..E.E.....Q...K......K.E.RLS...ELR.RKEKEIQDILAKKTEELKKIC..RR...EA..............EL........T.GKLPKE..Y..P..LSK.GE....R.....P..PQVRRR..V.GT..V..FK....LDE--LF.P.Y.............................N.ED.P..FLRNLE.SRFALQQKIVEAAKKLANESELCKT......................................................
A0A8C9UD08_SERCA/363-498 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A8I3NWA1_CANLF/341-405 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............E-........-.------..-..-..---.--....-.....-..------..-.--..-..--....-------.-.-.............................-.--.-..------.-------------------------ae....................................................
A0A437DET8_ORYJA/80-202 .............................................g-SKDPVILSSN.ASLIS.........A.......G............S..A.D.S.E..V..S..D.K.....K...R......K.E.KIA...EFT.KIQKDLQEKLKQKIQELKSIC..LR...EA..............EL........T.GRIPKE..Y..P..HDA.DE....K.....V..PEVARC..V.RA..P..FR....PQD---P.S.D.............................Q.QD.P..DFRDLE.SSLALQQRI----------------dlyktv................................................
A0A093J2E6_FULGA/103-237 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......R.E.KIM...ELK.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LSA.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..ALQDLE.SNFIIQQKLVEAAKKLASEPDLCKN......................................................
A0A7K8WUA7_9FURN/323-458 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A7K9IM87_9CORV/101-235 ..............................................EAKNQLIMASN.GSLIS.........S.......G............S..Q.D.S.E..V..S..E.E.....Q...K......K.E.KIM...ELK.KKEKLLQEKLLQKVEELKKIC..LR...EA..............EL........T.GKMPKE..Y..P..LGA.GE....E.....P..PQVRRR..V.GT..A..FK....LDD-NLL.P.S.............................E.ED.P..TLQDLE.SNFIIHQKLVEAAKKLASEPDLCKN......................................................
A0A6P3FA29_OCTDE/372-507 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKRLC..LR...EA..............EL........T.GKLPVE..Y..P..LDP.GE....E.....P..PVVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
A0A7L2IV73_9PICI/191-326 .............................................g-SKGKIISGSS.GSLLS.........S.......G............S..Q.E.S.D..S..S..Q.S.....A...K......K.D.MLA...ALK.SRQEALEETLRQRLEELKKLC..LR...EA..............EL........T.GKLPRE..Y..P..LDP.GE....E.....P..PIVRRR..I.GT..A..FK....LDEQKIL.P.K.............................G.EE.A..ELERLE.REFAIQSQITEAARRLASDPNVSKK......................................................
#=GC seq_cons ...............................................uKsplI.uSs.GSLlS.........S.......G............S..p.-.S.-..s..s..p.p.....t...K......+.-.hlt...tL+.p+pcsLpEpLpp+lEELK+lC..LR...EA..............EL........T.G+LPcE..Y..P..Lss.GE....c.....P..PpVRRR..l.GT..A..FK....LD-.plh.P.p.............................s.E-.s..tLppLE.pcFulQppIsEAA++LAs-PslsK.......................................................
//
