#=GF ID Cas_CXXC_CXXC
#=GF AC PF09706.14
#=GF DE CRISPR-associated protein (Cas_CXXC_CXXC)
#=GF AU TIGRFAMs;
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE TIGRFAMs
#=GF GA 21.00 21.00;
#=GF TC 21.40 21.10;
#=GF NC 20.90 20.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF DR INTERPRO; IPR019121;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC CRISPR is a term for Clustered, Regularly Interspaced Short
#=GF CC Palindromic Repeats. A number of protein families appear only in
#=GF CC association with these repeats and are designated Cas
#=GF CC (CRISPR-Associated) proteins. This entry describes a conserved
#=GF CC region of about 65 amino acids from an otherwise highly
#=GF CC divergent protein found in a minority of CRISPR-associated
#=GF CC protein regions. This region features two motifs of CXXC.
#=GF SQ 128
#=GS A0A7V7UDD2_9FIRM/220-283 AC A0A7V7UDD2.1
#=GS A0A386PEG3_CLOSE/223-289 AC A0A386PEG3.1
#=GS K0AUZ5_GOTA9/223-286 AC K0AUZ5.1
#=GS A0A416BHG2_9FIRM/232-296 AC A0A416BHG2.1
#=GS A0A0R3JXQ7_CALMK/250-314 AC A0A0R3JXQ7.1
#=GS A0A7G1G5A9_9BACT/225-292 AC A0A7G1G5A9.1
#=GS A0A4U7NCJ8_9SPIR/242-299 AC A0A4U7NCJ8.1
#=GS C4FLM9_9AQUI/197-261 AC C4FLM9.1
#=GS L7VTG3_THES1/206-270 AC L7VTG3.1
#=GS A0A1H5UQC7_9CLOT/251-312 AC A0A1H5UQC7.1
#=GS A0A4P5P8T1_9ENTE/226-289 AC A0A4P5P8T1.1
#=GS A0A2U1S8F6_9EURY/95-156 AC A0A2U1S8F6.1
#=GS Y372_AQUAE/176-245 AC O66695.1
#=GS A0A364K7B6_9BACL/255-302 AC A0A364K7B6.1
#=GS A0A1M6TNR5_9CLOT/222-289 AC A0A1M6TNR5.1
#=GS A0A1G4FFL6_9FIRM/223-286 AC A0A1G4FFL6.1
#=GS A0A1D3L2U3_9EURY/92-153 AC A0A1D3L2U3.1
#=GS W6RZB8_9CLOT/263-325 AC W6RZB8.1
#=GS R6WG86_9FIRM/221-285 AC R6WG86.1
#=GS D3SNB6_THEAH/140-209 AC D3SNB6.1
#=GS A0A096CT58_9FIRM/220-287 AC A0A096CT58.1
#=GS A0A1I1YST6_9FIRM/240-303 AC A0A1I1YST6.1
#=GS A0A099W1L0_9LIST/224-287 AC A0A099W1L0.1
#=GS M1RTR3_9AQUI/399-458 AC M1RTR3.1
#=GS A0A4Z0D9K7_9FIRM/219-283 AC A0A4Z0D9K7.1
#=GS G8M1H2_ACECE/195-258 AC G8M1H2.1
#=GS A0A151B365_9CLOT/222-289 AC A0A151B365.1
#=GS A0A556UB02_9LACO/235-298 AC A0A556UB02.1
#=GS A0A6C1BX76_9AQUI/105-174 AC A0A6C1BX76.1
#=GS A0A410PJP9_9CLOT/227-291 AC A0A410PJP9.1
#=GS A0A2C9XT04_9ENTE/228-291 AC A0A2C9XT04.1
#=GS R7MJA8_9FIRM/226-294 AC R7MJA8.1
#=GS M1MQV7_9CLOT/256-329 AC M1MQV7.1
#=GS G2SNY6_LIGR2/228-294 AC G2SNY6.1
#=GS A0A1M5U425_9BACT/208-272 AC A0A1M5U425.1
#=GS A0A0R2BME1_9LACO/230-293 AC A0A0R2BME1.1
#=GS A0A496AMJ8_9BACT/125-186 AC A0A496AMJ8.1
#=GS A0A840UJ67_9FIRM/224-286 AC A0A840UJ67.1
#=GS A0A4R1QGM3_9BACI/263-318 AC A0A4R1QGM3.1
#=GS A0A0C1R4X3_9CLOT/261-325 AC A0A0C1R4X3.1
#=GS A0A242K8H3_9ENTE/229-292 AC A0A242K8H3.1
#=GS A0A416HC79_9FIRM/218-282 AC A0A416HC79.1
#=GS A0A1M6PR07_9CLOT/269-333 AC A0A1M6PR07.1
#=GS D7DSW3_METV3/146-200 AC D7DSW3.1
#=GS R6Z6E2_9CLOT/268-332 AC R6Z6E2.1
#=GS A0A845QW06_9CLOT/222-285 AC A0A845QW06.1
#=GS A0A4R3Z6Y5_9FIRM/219-283 AC A0A4R3Z6Y5.1
#=GS I7KAL3_9CLOT/67-125 AC I7KAL3.1
#=GS N2BD58_9FIRM/217-281 AC N2BD58.1
#=GS A6TQ81_ALKMQ/222-285 AC A6TQ81.1
#=GS A0A498R4Q9_9FIRM/207-270 AC A0A498R4Q9.1
#=GS A0A2W7MH91_9BACI/223-288 AC A0A2W7MH91.1
#=GS A0A0P1MJ37_9BACT/91-155 AC A0A0P1MJ37.1
#=GS A0A562JF00_9FIRM/219-281 AC A0A562JF00.1
#=GS A0A4U7NGM5_9SPIR/247-303 AC A0A4U7NGM5.1
#=GS A0A4R3K3F8_9FIRM/224-286 AC A0A4R3K3F8.1
#=GS A0A0F7DC48_9EURY/114-178 AC A0A0F7DC48.1
#=GS A0A1I2MD54_9CLOT/260-324 AC A0A1I2MD54.1
#=GS U2CTM4_9FIRM/265-328 AC U2CTM4.1
#=GS H2J3Z7_MARPK/88-148 AC H2J3Z7.1
#=GS A0A1S9CNH0_9FIRM/218-285 AC A0A1S9CNH0.1
#=GS I6YU39_MELRP/140-206 AC I6YU39.1
#=GS A0A511VA95_9BACL/264-322 AC A0A511VA95.1
#=GS A0A162MTV1_9FIRM/192-256 AC A0A162MTV1.1
#=GS A0A6S6QXF9_9FIRM/227-290 AC A0A6S6QXF9.1
#=GS A0A1N7Q4C1_9BACL/265-326 AC A0A1N7Q4C1.1
#=GS A0A4Q4IL44_9BACL/217-285 AC A0A4Q4IL44.1
#=GS A0A285BDK3_9FIRM/92-152 AC A0A285BDK3.1
#=GS A0A1W6WEK7_9FIRM/220-283 AC A0A1W6WEK7.1
#=GS S0FGH9_RUMCE/230-293 AC S0FGH9.1
#=GS A0A5C0SBY4_9CLOT/223-289 AC A0A5C0SBY4.1
#=GS F0SWC3_SYNGF/226-289 AC F0SWC3.1
#=GS A0A374DQS4_9FIRM/219-283 AC A0A374DQS4.1
#=GS A0A7U6GDL0_CALEA/210-273 AC A0A7U6GDL0.1
#=GS R1CHQ1_9FIRM/243-302 AC R1CHQ1.1
#=GS A0A1T4N5L7_9FIRM/222-285 AC A0A1T4N5L7.1
#=GS C7N976_LEPBD/236-299 AC C7N976.1
#=GS A0A1M6Q5C0_9AQUI/145-214 AC A0A1M6Q5C0.1
#=GS A0A6A7K4W4_9FIRM/223-286 AC A0A6A7K4W4.1
#=GS A0A7G9W4X2_9FIRM/222-285 AC A0A7G9W4X2.1
#=GS G4D310_9FIRM/225-288 AC G4D310.1
#=GS A8UTP8_9AQUI/145-214 AC A8UTP8.1
#=GS C8W341_DESAS/227-290 AC C8W341.1
#=GS V6QC53_9ENTE/225-288 AC V6QC53.1
#=GS A0A1M4TWS8_9FIRM/223-286 AC A0A1M4TWS8.1
#=GS A0A7X6CUE2_9FIRM/222-284 AC A0A7X6CUE2.1
#=GS B3EG01_CHLL2/93-157 AC B3EG01.1
#=GS A0A4Y7RBA0_9FIRM/207-271 AC A0A4Y7RBA0.1
#=GS A0A1M5U5G4_9FIRM/219-283 AC A0A1M5U5G4.1
#=GS Q8U1T2_PYRFU/130-192 AC Q8U1T2.1
#=GS A0A1M4M3E5_9FIRM/223-286 AC A0A1M4M3E5.1
#=GS A0A165Y185_9BACI/257-311 AC A0A165Y185.1
#=GS F2KRM7_ARCVS/115-179 AC F2KRM7.1
#=GS A0A0A7FX35_9CLOT/218-285 AC A0A0A7FX35.1
#=GS A0A109QJ69_9BACL/269-322 AC A0A109QJ69.1
#=GS A0A6H1WYY1_9FIRM/265-329 AC A0A6H1WYY1.1
#=GS G7M8P4_9CLOT/263-326 AC G7M8P4.1
#=GS R7L6H0_9CLOT/271-335 AC R7L6H0.1
#=GS Q8TJV9_METAC/95-156 AC Q8TJV9.1
#=GS R9T5P1_METII/226-288 AC R9T5P1.1
#=GS A0A7G9GWC7_9FUSO/220-283 AC A0A7G9GWC7.1
#=GS A0A1M5QD29_9FIRM/267-331 AC A0A1M5QD29.1
#=GS A0A1L8TKT4_9ENTE/212-275 AC A0A1L8TKT4.1
#=GS A0A1V1I0T5_9FIRM/267-331 AC A0A1V1I0T5.1
#=GS A0A0D8I9M8_9CLOT/223-286 AC A0A0D8I9M8.1
#=GS A0A017H4R1_9FUSO/224-287 AC A0A017H4R1.1
#=GS L7VKK7_THES1/207-271 AC L7VKK7.1
#=GS A0A1U7M8J6_TISCR/223-287 AC A0A1U7M8J6.1
#=GS S0JI13_9ENTE/226-290 AC S0JI13.1
#=GS Q184H0_CLOD6/267-331 AC Q184H0.1
#=GS A0A7W2J0T3_9CLOT/256-320 AC A0A7W2J0T3.1
#=GS A0A286RM55_9BACT/68-136 AC A0A286RM55.1
#=GS A0A0R2GA87_9LACO/229-292 AC A0A0R2GA87.1
#=GS A0A559QT69_9ALTE/24-81 AC A0A559QT69.1
#=GS J6HAZ2_9FIRM/228-291 AC J6HAZ2.1
#=GS N9XJA4_9CLOT/221-288 AC N9XJA4.1
#=GS A0A161WXU3_9CLOT/223-290 AC A0A161WXU3.1
#=GS C1DUL6_SULAA/222-286 AC C1DUL6.1
#=GS U6FQ41_LACHE/236-299 AC U6FQ41.1
#=GS A0A8A7KHW5_9FIRM/272-324 AC A0A8A7KHW5.1
#=GS A0A497XR84_9AQUI/143-212 AC A0A497XR84.1
#=GS Q5JGA1_THEKO/127-189 AC Q5JGA1.1
#=GS A0A1I2U834_9FIRM/226-289 AC A0A1I2U834.1
#=GS A0A430AKK7_9ENTE/230-294 AC A0A430AKK7.1
#=GS A0A1E5KXR0_9ENTE/225-288 AC A0A1E5KXR0.1
#=GS R6GHA1_9FIRM/218-282 AC R6GHA1.1
#=GS A0A150M4Q9_9BACI/248-306 AC A0A150M4Q9.1
#=GS B7AS02_9FIRM/238-302 AC B7AS02.1
A0A7V7UDD2_9FIRM/220-283 .............................k-SKFKYECFNCH-AP.IENLN.IE.MGFLNASGF.----D..S..SRKPSHVWN..Y..N.N.D..IA..I..CPVCKLVYSCVPAGFT.......
A0A386PEG3_CLOSE/223-289 .............................e--KAKYTCFTCDNKI.QKLSK.P-.-FAYDITWItKMGVD..G..SRKSSHYWN..F..Q.S.D..SN..I..CPICNLIYSCIPAGF-s......
K0AUZ5_GOTA9/223-286 .............................k-SKYKYDCFICD-SK.IKDLK.DD.LSFLNMIGF.----D..V..NRKSSHVWN..F..V.N.D..IA..I..CSLCKLIYSCVPAGIT.......
A0A416BHG2_9FIRM/232-296 ............................hk--KAKDLCIDCGMPI.GPKEK.NS.IAFMNEVGD.----D..F..TRKRSAFWD..C..K.A.D..AF..L..CPGCTFVYALSPLGF-r......
A0A0R3JXQ7_CALMK/250-314 ...........................qid---ELNKCSICH--E.GISFE.--.-EDFNEGKFlPLGVS..N..DYSANFFWR..L..E.N.K..YP..I..CDICKLVLLCAPAGIT.......
A0A7G1G5A9_9BACT/225-292 ............................is--KAKYNCCVCDRKI.TKLSK.P-.-ESFDLVWInKIGVD..Q..NRKSSHFWN..F..N.N.T..SY..I..CPVCNLVYACVPAGF-n......
A0A4U7NCJ8_9SPIR/242-299 ..........................kked--------------N.NKKVK.T-.-KYYNTSFVkSLTQD..L..EGKSSHFWN..H..N.P.D..VI..I..CPICAFIYACMPIGFT.......
C4FLM9_9AQUI/197-261 .............................q-KDKKFTCVICGDRP.AKKDT.N-.----YDTGFsPIFGL..N..KDAVNFAWN..F..N.T.K..LP..S..CDICEIVYFCYFAGLT.......
L7VTG3_THES1/206-270 ............................qr--KSANQCIECG-RN.VSSQKeGS.MRWLNDVGV.----D..I..KRKISNYWN..F..N.P.D..IV..V..CPICKTVYSCAPLGFY.......
A0A1H5UQC7_9CLOT/251-312 ...........................ans------YCSICN---.--IYP.SF.KEDFNESRFlILGVS..N..ENAFNFFWN..F..I.T.K..YP..I..CNLCKLVILCAPAGV-v......
A0A4P5P8T1_9ENTE/226-289 ............................he--KDKLSCTNCG-HP.IKKGD.IS.YSFINQAGY.----D..A..NRKQSNAWS..F..T.N.D..LF..M..CPACRLLYTCISAGFT.......
A0A2U1S8F6_9EURY/95-156 ...........................evs---YNGTCVSCGRRD.--AVK.T-.---FKRDYI.PLSGS..-..GSLKNYFSF..A..N.E.G..VE..Y..CSLCAILIQFAPLIMY.......
Y372_AQUAE/176-245 ..............................EDKNAPLCFFCRERH.TYVYK.GK.YRVFGAEHFtPLSAS..E..DTLPNLFWN..G..R.N.K..MY..L..CPYCEFYLFFAAFGFT.......
A0A364K7B6_9BACL/255-302 ..........................gtlq---------------.-----.--.---LEEMHFsPLGIS..-..AKIENVFWN..G..K.E.S..TY..I..SHLARLILFCIPLGV-c......
A0A1M6TNR5_9CLOT/222-289 ............................kd--NFKYSCFSCD-RL.ISNLS.K-.PNSYDLTWInKMGVD..M..SRKTSHFWN..F..Y.G.D..IF..I..CPICNLVYSCIPAGFT.......
A0A1G4FFL6_9FIRM/223-286 .............................k-SKYKYDCFTCD-EK.IKDMT.ND.LGFLNAIGF.----D..V..KRKASHVWN..F..N.N.D..IS..V..CPLCKLIYSCVPAGF-s......
A0A1D3L2U3_9EURY/92-153 ............................ne--DTSGDCISCGRRN.-----.-K.VKRWGKDKI.PLTGS..-..KKFVNYFSY..G..I.D.G..AD..Y..CPACTFAVQFVPIGMY.......
W6RZB8_9CLOT/263-325 ...........................mqy-----NSCSMCG-NE.VSIG-.--.-SNYYEGNFvPLAIS..N..ENAENMYWN..F..N.T.K..HP..I..CSLCKLILLCTSAGMT.......
R6WG86_9FIRM/221-285 ............................hk--KAKDLCIDCG--E.PMNTK.EK.VSIAFMNEI.--GDD..F..TRKRSAFWN..C..K.A.D..AF..L..CPACAFVYALSPLGF-r......
D3SNB6_THEAH/140-209 ............................re--TSDHTCFFCGERK.ASIHN.GE.PKTFEATNFtPLSAS..P..NTVENLFYN..G..K.N.N..LY..L..CSVCEIVFYFAGFGFT.......
A0A096CT58_9FIRM/220-287 .............................n-SNSNYNCFNCN-RK.ISKLS.K-.PASYDLTWInKIGVD..M..SRKTSHFWN..F..Y.G.D..AF..V..CPICNLVYSCIPAGFT.......
A0A1I1YST6_9FIRM/240-303 .............................k-VKYKYNCFLCD-SR.IKDMN.NN.LSFLTNTGF.----D..V..ARKSSHIWN..F..Q.N.D..IA..I..CDVCKLVYACMPAGF-v......
A0A099W1L0_9LIST/224-287 ............................le--KAKFNCTTCN-EP.IKNMK.LD.LSFMNETGF.----D..T..ARKTSHVWD..F..N.N.D..IA..V..CPMCKLIYSCVPAGFT.......
M1RTR3_9AQUI/399-458 .............................i--ETSQVCFFCHERQ.AKNIV.D-.-----ATNFtPLFSS..L..DTVKNFIWD..P..-.-.-..IP..I..CKECEFLLYFASAGFY.......
A0A4Z0D9K7_9FIRM/219-283 ...........................dkt--KYDYSCATCN-SP.ISNLD.NS.MSFMNNIGF.----D..T..GRKTSHVWN..F..F.F.D..LG..I..CPICKLVYSCVPAGF-i......
G8M1H2_ACECE/195-258 ........................eeklnf------SCFQCG-RG.IQKID.KG.LSFLNRMFF.----D..T..ARKTSHVWN..F..V.S.D..ID..I..CPICKIVYYCVPAGFT.......
A0A151B365_9CLOT/222-289 .............................k-KKYKYRCFSCDAPI.LKLSK.P-.-ASYDLTWLnKMGVD..M..SRKSSHFWN..F..Y.G.D..SF..I..CPVCNLVYSCIPAGFT.......
A0A556UB02_9LACO/235-298 ............................tk--KDKYICSNCN-RT.MPKQT.YS.YGFLNGMGY.----D..L..NRKTSNAWN..F..A.N.D..LY..I..CPICQLLYVATSAGFT.......
A0A6C1BX76_9AQUI/105-174 ............................ts--NNFPKCFFCKERN.SYKKE.NF.YKTFDAINFtPLSAS..P..NTFPNLFYN..G..V.N.T..MF..L..CKECEALLYFACFGFT.......
A0A410PJP9_9CLOT/227-291 ..........................dkkk---YKFSCITCN-KS.IKDLN.ND.LSFLNETGF.----D..V..GRKSSHVWN..F..T.N.D..IA..I..CPVCKLIYSCIPAGM-v......
A0A2C9XT04_9ENTE/228-291 ............................hk--KDKLSCTNCS-RP.IKKGN.IS.YSFINQVGY.----D..V..NRKQSNAWG..F..T.N.D..LF..M..CPICRLLYTCVPAGFT.......
R7MJA8_9FIRM/226-294 qkkksaicieclgtmsatevqkkkrrltfl---------------.-----.--.--------F.DIADD..L..DRKKSYYWF..C..K.P.D..AY..V..CPLCNFIYAFIPLGF-a......
M1MQV7_9CLOT/256-329 ..................krkaesvndvle---NYNICRICD---.-DNIS.F-.GDDYTDGNFiPLAIS..N..ANSKNLFWM..F..D.S.R..YP..I..CPLCKLVLFCTAAGCT.......
G2SNY6_LIGR2/228-294 .............................h-DKDKYLCSTCG-RR.IKKGK.R-.-CSYSYSFInGMGYD..V..EKKKSNSWN..Y..V.N.D..LL..I..CPICNFMYSAIPAGF-n......
A0A1M5U425_9BACT/208-272 ..........................ksgy----KHNCFVCNNKI.NKQFS.NS.ISFINNIGF.----D..I..TRKTSNVWN..F..N.N.D..IF..L..CPVCTFVYSNIPAGF-i......
A0A0R2BME1_9LACO/230-293 .............................h-SKDKYHCSNCN-RP.VTKTD.LS.YTFLNDMGF.----D..T..ARKTSNVWD..F..N.N.D..LT..I..CPICQLMYSCSSAGF-n......
A0A496AMJ8_9BACT/125-186 ............................dl--NEAGNCIGCGRRE.ANIWL.--.----SKTNV.PLTGS..-..GTLRNFFPA..F..A.D.G..AE..Y..CTACTLAIQLSPLVF-l......
A0A840UJ67_9FIRM/224-286 .............................e-KKSSRHCIVCD--A.VMSKP.ID.ISFLNDSAD.----D..M..SRKKSAFWN..C..K.P.D..AQ..L..CPLCAFIYSMSPLGFT.......
A0A4R1QGM3_9BACI/263-318 ......................lsdhvafy---------------.-----.--.--NFEEMVFsPIGVA..K..NNAFNFNWN..L..E.D.RqpKP..I..CSLAKLVLFFAPAGA-a......
A0A0C1R4X3_9CLOT/261-325 ............................id--ENYYTCSMCC--N.EKSLG.--.-HNFSEGDFlPLGVS..N..DNTRNMFWN..M..N.I.T..YP..I..CDICRLILICTPAGT-v......
A0A242K8H3_9ENTE/229-292 ............................qt--KYKYHCANCN-RK.IKDLK.ND.VSFLNATGF.----D..V..SRKAGHVWD..S..F.N.D..TA..V..CPLCKLVYSCVSAGFT.......
A0A416HC79_9FIRM/218-282 ............................he--KSKEYCIECN--A.MIDSK.EE.VSIAFMNDM.--ADD..L..ARKRSAFWN..C..K.V.D..AY..I..CPLCAYLYTLVPLGF-r......
A0A1M6PR07_9CLOT/269-333 ..............................YVDSLETCQMCG---.--NIK.GI.MDIYTESNFaPLAVS..S..DNALNLYWN..M..N.P.D..TN..I..CPLCKLILFCTPAGTT.......
D7DSW3_METV3/146-200 ....................epqkndkfek---------------.-----.--.--FIGRELF.PLIGS..Y..GNDAQILPA..S..S.K.A..PH..I..CPKCLFAVNFLPLS--tm.....
R6Z6E2_9CLOT/268-332 ..........................kekv----IKSCSMCE-NE.IGLTT.N-.---YSEGNFvPLAIS..S..DNARNFFWN..Q..N.V.K..MP..I..CDVCKLILFCIPAGMT.......
A0A845QW06_9CLOT/222-285 .............................k-SKYKYNCFNCD-NQ.IKDLK.NH.YGFLNNIGF.----D..V..DKKASHVWK..F..N.N.D..AA..M..CPICKLIYSCTPAGI-m......
A0A4R3Z6Y5_9FIRM/219-283 .............................k-SKMKDQCVDCG--N.PINNK.TG.VSISFMNDF.--ADD..L..VRKRSALYN..F..N.V.D..MN..L..CPICTFLYALTPLGF-i......
I7KAL3_9CLOT/67-125 .............................y-------CSICN---.--IYP.SF.KEDFNESRFlILGVS..N..ENASNFFWN..F..I.T.K..YP..I..CNLCKLVILCAPAGV-v......
N2BD58_9FIRM/217-281 ............................he--KDKNMCIDCG-RL.FRDKK.KA.GITFMKDQA.---DD..L..TRKRSAFWN..G..K.E.D..AY..L..CPVCSYLYALVPLGFT.......
A6TQ81_ALKMQ/222-285 ..............................KSTKKYNCFTCD-RE.MKDLK.ND.LSFLNQVGF.----D..V..SRKASHTWD..F..V.N.D..IA..I..CPICKLVFSCVPAGMT.......
A0A498R4Q9_9FIRM/207-270 .........................kkiql------TCCQCD---.VPISK.N-.-DSFPMAWInDLGVD..V..ARKTSHYWN..F..K.V.D..SF..L..CPVCNLIYACIPLGFT.......
A0A2W7MH91_9BACI/223-288 .............................y-EKNKLHCALCE-NT.MGKLS.ET.---FDLTWLqKMGVD..S..ARKSSHYWN..H..Q.K.D..LF..I..CPICNLIYSCVPLGFT.......
A0A0P1MJ37_9BACT/91-155 ...........................lsd----SGACVSCGKRN.KSRVE.RK.FG-IGKELV.PLTGS..-..GDFVNFFPM..A..S.L.G..LE..M..CSACLLAIQFMPI---fl.....
A0A562JF00_9FIRM/219-281 ............................tk--KKTKRCIECS-NL.AYNTK.S-.ISFMIDSTD.----D..V..SRKKSHYWN..L..K.P.D..AF..V..CPVCAFLYTLVPLGF-q......
A0A4U7NGM5_9SPIR/247-303 ..........................nsnn---------------.EKELK.T-.-KPYSTSFInGLAQD..L..EGKSSQFWN..H..N.P.D..VR..I..CPLCAFIYACVPIGF-i......
A0A4R3K3F8_9FIRM/224-286 .............................e-KKSSRHCIVCD--A.VLAKP.ID.ISFLNDSAD.----D..M..ARKKSAFWD..Y..K.P.D..AH..L..CPICAFVYSLAPLGF-v......
A0A0F7DC48_9EURY/114-178 ............................sd--NDSPTCVLCGRRP.AYSKK.DI.Y----LSVF.PLLGT..-..GGVPNFFHS..A..NlR.G..AD..I..CAHCVFLAQFMPLISY.......
A0A1I2MD54_9CLOT/260-324 ..........................mdgt----YNKCCLCD--E.NLSYG.--.-SDYSDGNFiPLAIS..N..DGCKNLFWD..M..N.S.K..FP..I..CPLCRLILLCTAAGTT.......
U2CTM4_9FIRM/265-328 ..........................gkdf-----ALCQMCG---.--EYK.SI.GSEYGEGDFvPLAVS..T..DNSRNMFWN..F..N.T.S..VP..L..CDICKLILICSAAGAT.......
H2J3Z7_MARPK/88-148 .............................s--DASGYCRICG-KK.GKNFK.V-.----GRETF.PLSGS..-..GKFVNFHHG..H..E.N.G..IL..L..CNDCITKLFFLPLA--vl.....
A0A1S9CNH0_9FIRM/218-285 ............................he--KDKYQCTQCCNPI.SKLSK.P-.-ASYDLTWLkRIGVD..G..GRKSSHFWN..Y..N.A.D..AI..I..CPACRMVYACMPLGF-s......
I6YU39_MELRP/140-206 ..........................qpav-----TKCTFCLREA.NATLK.NT.---FTSEHSkLLGAA..SgdKGVPNSFWN..MnkE.N.S..IA..V..CDYCSFIL--------lsnhl..
A0A511VA95_9BACL/264-322 .....................ctlvlgqps---------------.-----.--.FQNFEEMIFsPLGVS..S..KNAANFFWD..L..E.Q.NrsLP..I..SSLAKLVLFCVPLGAT.......
A0A162MTV1_9FIRM/192-256 ............................ey--DRNNSCLICGQRK.AK--R.DA.MLDTGLVSF.-LGAN..-..KDNKNFFWN..F..K.P.K..LP..I..CEICELIYFSIFAGL-t......
A0A6S6QXF9_9FIRM/227-290 .............................q-SKYKNECFTCG-MP.MKDFN.ND.MSFLNQFGF.----D..I..ARKTSHVWN..F..Y.N.D..IA..V..CPICKLIYSCLPAGFT.......
A0A1N7Q4C1_9BACL/265-326 ................mshctliegqlati---------------.-----.--.--NFEEMMFsPLGVS..Q..NKALNFNWN..L..A.K.DetIP..I..SSLAKLILFCAPAGA-a......
A0A4Q4IL44_9BACL/217-285 ............................he--NDKYCCFNCG-KP.IKKLS.K-.PAAFDLAWMnRMGVD..M..NRKSSHFWN..L..N.SsT..CY..I..CPICNFVFSCVPTGFT.......
A0A285BDK3_9FIRM/92-152 .............................i--DTDGNCIACGRRS.SNKP-.--.---YTKTQI.PLTGS..-..SDFINFFSY..G..K.E.G..AD..Y..CPACVLAIQFAPLVFY.......
A0A1W6WEK7_9FIRM/220-283 ............................kg--KKVMSCFQCG-RA.L-QAK.AS.STAWVNDTM.---PD..V..KRKTDSFWN..Y..V.P.D..IM..M..CPYCMLVYACVPLGFT.......
S0FGH9_RUMCE/230-293 ...........................kqk---FRYKCFTCG-AP.IRDMN.ND.MSFLNQSGF.----D..T..ARKPSHVWD..F..V.N.D..IA..L..CPVCKLIYSCLPAGF-v......
A0A5C0SBY4_9CLOT/223-289 .............................e--KAKYKCFVCD-RK.ISKLS.K-.PVSYDLTWInKMGVD..M..SRKTSHFWD..L..S.G.D..TF..I..CPICNFVYSCIPAGFT.......
F0SWC3_SYNGF/226-289 .............................k-DKFKYHCFICD-EP.IKDMS.LD.LSFMNATGF.----D..V..ARKSSHVWD..F..Q.N.D..IA..V..CPLCKLIYSCLPAGFT.......
A0A374DQS4_9FIRM/219-283 ............................hk--KAKDLCIDCGDPI.GPKEK.IS.IAFMNEVG-.---DD..F..TRKRSAFWD..C..K.V.D..AF..L..CPGCAFIYALSPLGF-r......
A0A7U6GDL0_CALEA/210-273 ...........................kqe---SELYCVNCG-RP.A---K.KD.TS--FDTGIsPFFGI..N..KDASNFLWK..F..N.T.K..LP..L..CEICELIYFCSFAAL-t......
R1CHQ1_9FIRM/243-302 .................iphcsiweeylat---------------.-----.--.-SDFTEAVFvPLAVS..N..NNAKNFMWQ..G..N.T.S..YP..I..CSLVKFILFCTPAGVT.......
A0A1T4N5L7_9FIRM/222-285 ............................ke--KFKYNCFVCD-RK.MNNMN.ND.LSFLNKTGF.----N..V..SNKPSHVWY..F..A.N.D..VA..I..CDLCKFVYSCLPAGF-v......
C7N976_LEPBD/236-299 .............................k-SKFKYKCVLSN-ML.MKDYK.NT.LGFLNDTGF.----D..V..NRKPSHVWN..F..V.N.D..IA..V..TPLVTLVYSCVPAGF-i......
A0A1M6Q5C0_9AQUI/145-214 .............................y-KTSDKTCFFCGERK.AYIKN.KE.VKVFDATNFtPLSAS..P..KTVENFFYN..G..R.S.N..QY..L..CPECEIFLYFSIFGF-l......
A0A6A7K4W4_9FIRM/223-286 ............................ka--TYKYNCFVCN-KG.ITDLK.ND.LSFLNNTGF.----D..V..SRKSSHVWH..F..N.N.D..VA..L..CPVCKLVYSCIPAGMT.......
A0A7G9W4X2_9FIRM/222-285 ............................ts--KFKYKCFNCH-RE.MKDLN.ND.LSFINNIGF.----D..V..SRKPSHVWE..F..N.N.D..IA..I..CPVCKLIYSCIPAGFT.......
G4D310_9FIRM/225-288 .............................k-NKSRYLCMSCG-SR.ISSLN.ND.ICFIRELGF.----D..T..KKKNSHVYD..F..N.N.Y..VG..I..CPMCKLVYTCIPAGFT.......
A8UTP8_9AQUI/145-214 .............................y-QKSKKVCYFCKERH.AYIKK.GK.VKVLDATNFtPLAAS..L..DTVENFFWE..G..K.S.N..MY..L..CPECEIFLYFSAFGF-h......
C8W341_DESAS/227-290 ............................kg--KYKYNCFVCD-AP.IKDMS.ND.LSFLNATGF.----D..V..ARKSSHVWN..F..Q.N.D..IT..I..CPLCKLIYSCLPAGI-i......
V6QC53_9ENTE/225-288 ..........................ksly----KLTCCSCE-NP.VKNAS.ET.LSFLNKTGF.----D..V..NRKNSHAWD..F..I.N.D..LI..I..CPVCKLIYACIPAGFT.......
A0A1M4TWS8_9FIRM/223-286 .............................k-SKFKYNCFSCD-KS.MKDFS.ND.LSFLNSTGF.----D..V..SRKSSHVWE..F..Q.N.D..IA..V..CPICKLVYSCVPAGI-s......
A0A7X6CUE2_9FIRM/222-284 .........................khaih-------CCQCNSSV.RKSEA.KS.MSWINDEGV.----D..I..ARKTSYYWN..H..N.P.D..SY..L..CPLCAMIYTCLPLGF-h......
B3EG01_CHLL2/93-157 ...........................lad----HGSCVACGCRN.AIKIK.KE.KRGLLRSEV.PMAS-..-..-GSLNYYSF..A..S.T.G..AD..Y..CGTCAIAIQVSPLVLY.......
A0A4Y7RBA0_9FIRM/207-271 ...........................syk---AKDYCIECGISLpTSLSK.G-.LSWLNDMGV.----D..H..KRKYSYFWN..F..K.P.D..SY..L..CPLCAFIYSCTPLGF-s......
A0A1M5U5G4_9FIRM/219-283 ..........................dkek---YKFECFSCG-SK.IKNLS.IN.MNLVKNTGF.----D..S..ARKTSNIWN..H..E.S.D..FA..I..CPKCQFLYSCLSAGF-f......
Q8U1T2_PYRFU/130-192 .............................e-DPNAPICEICGRRH.SR-SK.P-.---VYRSEF.PLIGS..-..GGVPNYFPS..G..K.E.G..AN..I..CSHCLFLVQFLPLIL-y......
A0A1M4M3E5_9FIRM/223-286 ........................ksrfrf------SCFSCN-RS.MKDLT.ND.LSFLNSTGF.----D..V..SRKSSHVWD..F..Q.N.D..IA..V..CPICKLIYSCVPAGI-s......
A0A165Y185_9BACI/257-311 .........................dewya---------------.-----.--.FEHLNEGHFvPLQVS..S..SNALNYFWD..F..D.N.E..MK..IpiSNLAKFILFCAPAGA-a......
F2KRM7_ARCVS/115-179 ...........................nnr---DSPKCVLCGRRP.AYTKK.E-.--VY-LSVF.PLLGT..-..GGVPNFFHS..A..NtR.G..AD..I..CAHCIFLTQFMPLASY.......
A0A0A7FX35_9CLOT/218-285 .............................n-MKNKYNCFTCENKI.SKLSK.P-.-EAFDLTWIvKTGVD..M..TRKSSHFWE..L..K.G.D..AY..I..CPICNLVYSCIPIGFT.......
A0A109QJ69_9BACL/269-322 ..........................gqpa---------------.-----.--.FQNFEEMMFsPLGVS..S..KNAANFFWD..L..E.K.N..RAlpI..SSLAKLVLFCVPLGAT.......
A0A6H1WYY1_9FIRM/265-329 ............................yl--DSLEICEMCG---.--TYK.GL.INDYSESNFaPLGVS..N..DNAKNMFWN..Q..D.S.T..YS..I..CDLCKLILFCTPAGST.......
G7M8P4_9CLOT/263-326 ...........................len----YNTCRICD---.-ENLS.F-.GDDYTDGSFiPLAIS..N..ANSKNLFWK..F..D.S.R..YP..I..CPLCKLVLFCTSAGCT.......
R7L6H0_9CLOT/271-335 ..........................kkdv----FKVCYLCA---.--DEH.CI.TSNYSESNFlPMAVS..S..DNMKNFFWN..Q..K.V.N..YP..I..CDMCKLIMFCIPMGLT.......
Q8TJV9_METAC/95-156 .............................d-VLTSGNCVTCGRRN.VEQIR.T-.-----KTEI.PLIGS..-..GGMINYFPS..G..Q.P.G..AD..Y..CPACTFAVQFSPLVSY.......
R9T5P1_METII/226-288 ...........................tks---KTKPCIDCG--R.LSKTT.TS.LSFMSDVTD.----D..T..NRKKSYYWN..C..V.P.D..AY..L..CPLCAFIYSLVPLGF-s......
A0A7G9GWC7_9FUSO/220-283 .............................s-DKYKYNCFICD-RK.IKNLN.SD.FNFLTNTGF.----D..I..ARKSSHVWN..F..T.N.D..IS..M..CPVCKLVYSCVPAGFT.......
A0A1M5QD29_9FIRM/267-331 ..............................YMDKLESCEMCG---.--MYK.GI.IDEYSESSFvPLGVS..N..SNAKNMFWN..Q..E.D.A..YE..I..CDICKLILFCTPAGAT.......
A0A1L8TKT4_9ENTE/212-275 ............................hd--KDKLSCTNCE-RS.IRKGE.IP.YTFINNAGY.----D..M..GKKQSNAWS..F..T.N.D..LF..M..CPVCRLLYTCISAGFT.......
A0A1V1I0T5_9FIRM/267-331 ............................yl--ESLETCEMCG---.--TYK.GL.INDYSESNFaPLGVS..N..DNAKNMFWN..Q..D.S.T..YS..I..CDLCKLILFCTPAGAT.......
A0A0D8I9M8_9CLOT/223-286 ...........................ats---EKFNCFTCG-RS.IKDLK.ND.LSFLNNIGF.----D..V..SRKSSHTWN..F..S.N.D..VA..V..CPICKLVLSCTPAGIT.......
A0A017H4R1_9FUSO/224-287 ............................kt--KFKYRCFSCG-EA.IKDTR.ID.LSFMNHIGF.----D..V..ARKTSHVWD..F..N.N.Y..VH..I..CPLCRLIYACVPAGFT.......
L7VKK7_THES1/207-271 ..........................knkg----ALQCIQCGNPI.NASLG.MG.MSWLNDVGI.----D..M..ERKRSHFWN..F..N.P.D..TY..I..CPVCALVYSCVPLGFT.......
A0A1U7M8J6_TISCR/223-287 .........................gkfkl------NCFITG---.-LPIK.SK.SSAYDMGFLiDTGFD..T..NRKTSHVWD..F..N.N.D..IF..I..CALARMIYSCMPCGM-f......
S0JI13_9ENTE/226-290 ............................ks--KYKFSCCSCQ-QP.IKSLK.NDtLSFLQKTGY.----D..V..ARKNAHAWE..F..Q.N.D..LA..I..CPLCKLLYACLPAGMT.......
Q184H0_CLOD6/267-331 ..............................YMDSLEVCEMCG---.--LYK.GI.LDEYSESNFaPLGVS..T..NNARNMFWN..Q..A.Y.V..PS..I..CDICKLILFCTPAGAT.......
A0A7W2J0T3_9CLOT/256-320 ............................ns--PKLYNCSLCG---.--EFK.SL.GYDFEEKVFsPLGIS..S..GNAYNLFWN..F..N.T.E..FP..I..CNMCKLILFCTPAGAT.......
A0A286RM55_9BACT/68-136 ...........................gng-----DTCSFCFRNS.RFSYK.N-.--IFTSEHSkLLGASagE..RGVPNSFWN..L..N.P.EqsLR..I..CDFCNFVLL-------nhhlalt
A0A0R2GA87_9LACO/229-292 .............................h-SKDKYRCSSCG-RP.IAKRE.FS.YSFLTDMGF.----D..A..ARKTSNVWD..F..N.S.D..LY..I..CPICQLMYSCASAGF-n......
A0A559QT69_9ALTE/24-81 .........................svfic------NCSFCIRRS.ATLVK.T-.----TKENF.TLNSD..E..NNLKSYGNN..G..V.S.R..HY..F..CPDCGIH---------cftk...
J6HAZ2_9FIRM/228-291 ............................rl--KSKYRCVTCN-AK.IKNLD.ID.LSFMREIGF.----D..V..NRKTSHVWD..F..N.N.Y..VA..I..CPVCRLVYACVPAGFT.......
N9XJA4_9CLOT/221-288 .............................k-EKYKYNCFICDNKI.SKLGK.P-.-DSYELTWLvKTGVD..S..SRKSSHFWN..L..N.S.D..AY..I..CPICNLVYSCVPLGF-n......
A0A161WXU3_9CLOT/223-290 .............................k-TKYKNNCFTCD-NK.IKKL-.GK.PEAFDLTWLvKTGAD..M..SRKSSHFWN..M..N.G.D..AY..I..CPICNLVYSCLPLGF-v......
C1DUL6_SULAA/222-286 .............................k-KDKKFLCISCMERK.AK--K.DT.IFDTGISKFyGLNPD..-..--VINFSWN..F..N.P.K..IP..L..CEICEIIYFSYFAGL-t......
U6FQ41_LACHE/236-299 .............................h-SKDKYICSTCG-RP.IKRLE.YS.YGFLNDMGY.----D..L..NRKTSNAWN..F..K.N.D..LY..I..CPVCQFLYSLVPAGFT.......
A0A8A7KHW5_9FIRM/272-324 .......................nksnmgc---------------.-----.--.--EFTESVFiPLAVS..L..KKSKNFMWN..G..N.I.S..LP..I..CNLLKLVLLAAPAGAT.......
A0A497XR84_9AQUI/143-212 ............................sk--RSNKLCFFCQERK.AYIKK.DK.VKTFDATNFtPLGAS..P..ETLENLFWN..G..R.S.N..MY..L..CPECEIFLYFSAFGFT.......
Q5JGA1_THEKO/127-189 ...........................edp---RAPICEICGRRH.A-RIK.PV.Y----RSDF.PLVGT..-..GGVPNYFPS..G..K.D.G..AN..I..CSHCLFLAQMMPLVAY.......
A0A1I2U834_9FIRM/226-289 .............................k-SKFKYNCFVCN-AP.IKDMS.ND.LSFMNATGF.----D..V..ARKASHVWN..F..Q.N.D..TA..I..CPLCKLIYSCLPAGIT.......
A0A430AKK7_9ENTE/230-294 ..........................dktk---YKFSCCTCE-QP.IKNLD.ET.FSFLVETGY.----D..T..KRKGSHGWN..F..V.N.D..MG..L..CPICKLIYACIPAGFT.......
A0A1E5KXR0_9ENTE/225-288 ............................ke--KYKHHCSNCN-QP.MKNYK.ND.LNFLNQTGF.----D..A..NRKTSHVWN..F..N.N.D..IA..V..CPMCKLVYSCLPAGFT.......
R6GHA1_9FIRM/218-282 ............................ht--KAKDLCIDCGEPV.TTKEK.VS.IAFMKEVG-.---DD..F..TRKRSAFWN..C..N.V.D..AF..L..CPVCTFLYAASPLGF-r......
A0A150M4Q9_9BACI/248-306 .....................csftdfpia---------------.-----.--.LHSFDEGIFvPLALS..I..GNAINMTWDsnG..K.E.L..LP..L..CSLSRLLIFCSQAGAT.......
B7AS02_9FIRM/238-302 .............................h-DKDKDMCIDCA-RP.MGN-K.EK.VSIAFMKDM.--ADD..L..ARKKSAFWN..C..K.V.D..AF..L..CPACAFVYALSPLGFT.......
#=GC seq_cons .............................p..p.p.pCh.Cs.p..htphp.t..hs.hspssF.....s..h..s+ppsahWs..h..p.s.c..hh..l..CPlCpllatCsPhGh........
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