#=GF ID   Cas_Csa5
#=GF AC   PF09702.14
#=GF DE   CRISPR-associated protein (Cas_Csa5)
#=GF AU   TIGRFAMs;
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   TIGRFAMs
#=GF GA   23.00 23.00;
#=GF TC   24.20 23.90;
#=GF NC   22.80 21.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR010157;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   CRISPR is a term for Clustered, Regularly Interspaced Short
#=GF CC   Palindromic Repeats. A number of protein families appear only in
#=GF CC   association with these repeats and are designated Cas
#=GF CC   (CRISPR-Associated) proteins. This entry represents a minor
#=GF CC   family of Cas proteins found in various species of Sulfolobus
#=GF CC   and Pyrococcus (all archaeal). It is found with two different
#=GF CC   CRISPR loci in Sulfolobus solfataricus.
#=GF SQ   18
#=GS A0A2R4ZRK4_9CREN/18-127  AC A0A2R4ZRK4.1
#=GS Q97WW4_SACS2/6-112       AC Q97WW4.1
#=GS F4B6T0_ACIHW/16-123      AC F4B6T0.1
#=GS A0A7J0E7M1_9ERIC/1-97    AC A0A7J0E7M1.1
#=GS W7L474_9CREN/18-117      AC W7L474.1
#=GS A0A2U9IGQ8_9CREN/12-113  AC A0A2U9IGQ8.1
#=GS A0A2H5V4Q4_9ARCH/30-137  AC A0A2H5V4Q4.1
#=GS CSA5B_SACS2/17-130       AC Q97Y90.1
#=GS A0A7L9FLH5_9CREN/10-106  AC A0A7L9FLH5.1
#=GS H2C0V9_9CREN/24-135      AC H2C0V9.1
#=GS D5U1S7_THEAM/8-104       AC D5U1S7.1
#=GS A4YFV3_METS5/11-116      AC A4YFV3.1
#=GS A0A348B5X5_9CREN/17-123  AC A0A348B5X5.1
#=GS Q96X70_SULTO/18-136      AC Q96X70.1
#=GS Q5JGB0_THEKO/15-110      AC Q5JGB0.1
#=GS A2BKJ1_HYPBU/13-107      AC A2BKJ1.1
#=GS A0A0U3ED29_9CREN/13-115  AC A0A0U3ED29.1
#=GS A8ABL6_IGNH4/18-126      AC A8ABL6.1
A0A2R4ZRK4_9CREN/18-127             ......LVATASI..YTESLNLIDRLAYALNPESAIKSLNDSLRIVEGAVRRGEVGeave....kseggGDR-....-SVIKIRVGDG....REYRlLYCSLPNVEVVRRFLEEVRRN..IEVA...RTIGTLANS-m.....................................
Q97WW4_SACS2/6-112                  ......LLAVGFL..YSESPTLVDRFANALSKEAVTKVLYDVQRIVQMGIDRGEIVstt.......tmiQGKE....YPAVNVS-SSE....GKYT.VVGYLPTNQDIEYFLRMIEED..VYYA...RKAGALAMSI......................................
F4B6T0_ACIHW/16-123                 ......LFATTYL..YSESSMLVDRFANALSKEAVAKVLYDAQRIVQMGLDRDEIKsdi.......vkiKEKD....YPAIVITKEKE....KSVQ.IIGYLPTDQDVEDFLSLIEKD..VYYA...RKAGALAMSI......................................
A0A7J0E7M1_9ERIC/1-97               ....ml------I..ASKSKVEIDKLKAQLSQEFEMKNLGEAKKIMGMEIKRDRVK.............DDER....KHMANVPYANA....VGAL.MYAMVCTRPDISHAVSMVNRD..----...----------nkssqysvgyvds.........................
W7L474_9CREN/18-117                 ......LLAVATL..YANAPTFTDRMSNALNKESVMRALYDAERVVLAGKNKGDIT.............EGKA....--VISVKVAEN....ETAK.VYGYLPSDLDVEEFLRMAERD..IYIA...RKVGAIAISK......................................
A0A2U9IGQ8_9CREN/12-113             ......LLATSSL..YTDSPTLIDRIANALSKEAITKVLNDSQRIIESGISKGDIF.............QNKK....DDHPIISIKGE....KMLS.IYGYLPTTSDIENFLLEVEKD..IYNA...RKAGAIAMSI......................................
A0A2H5V4Q4_9ARCH/30-137             ......LLAAASA..MTGSPSLIDRMTYALGPEPAMKAVADALRIVQSDLSSQRPAis........qgaSEKG....YPEVRVRDEAG...nTSVV.IPGRLPGSETVRNFLEEVSRD..VSIA...RKIGTYASS-l.....................................
CSA5B_SACS2/17-130                  ......LLAVGFL..YSESPTLVDRFANALSKEAVTKVLYDVQRIVQMGIDRSEIAtttitiqgkdypaQGKD....YPAVNVN-SSG....AKYT.VVGYLPTSQDIEDFLRMIEED..VYYA...RKAGALAMSI......................................
A0A7L9FLH5_9CREN/10-106             ...vlr---F-FA..ATRNYSFLDRIGNALNPETVEVALRDALRTFSSIYDASP--.............ADEK....-GLKYYEYEEG....RRIR.LPAK-PSEGEVAAFLRAVWQD..VGVA...RRVAIMAMS-v.....................................
H2C0V9_9CREN/24-135                 ......ALALAAL..VQESTTVIDRMAYALTPEQSVRALNDALRTIASVS-QGSTSfqvsq...vqvkkEENT....YTFTEVKEREG...nMRYK.IPGGLPTQEEVTDFIDAVTAD..VRLA...RKVGAVALS-l.....................................
D5U1S7_THEAM/8-104                  ilaylg-------..SQKDYSYIDRLGNAIDEISIMEALRDAVRSFITICEKPESKcpsid..fqeldkS---....-----------....----.---------------------..----...----------lntllavisskpreqvikmarelslkayakiktfetsq
A4YFV3_METS5/11-116                 ......LLATASI..YAETPTLLDRISNALSKEAAVKVIGDCERIVNTGLNRGEIRl...........qTGEN....-PRIYIDVKEGe.rtKTYE.LYGSLSSSEDVTQFIEDVERD..IYTA...RKVGAVAMA-t.....................................
A0A348B5X5_9CREN/17-123             ......MLAAAVL..YSGSPGVVDRMANALSKEAVAKVLNDAQRIVSVGIDRGEVVaqr.......sssGQAD....YVVVTVR-TVD....RTYT.LYGTLPSPGDVEDFTRELEKN..IYVA...RKVGALAMA-a.....................................
Q96X70_SULTO/18-136                 ......LLASVFI..YSESPTYVDRFANALSKEAVARVIYESQRIIQMGISSGEVKmgnveisgksmkiTDKKgeesYPAVIIKTKEG....RNYI.VVGYLPTDKDVEDFMSLVERD..IYYA...RKAGALAMSI......................................
Q5JGB0_THEKO/15-110                 ...mlr---F-FV..QTKNFSYVDRIGNALNPEPVEVALLEALRAFRSIRESASIE............gDGRR....----YVE-KDG....NKIP.MPG-IPSDEEVKIFLDDVRSD..MGVA...KLVATLALA-y.....................................
A2BKJ1_HYPBU/13-107                 ......LLSF-FA..RTRQFGVLDRIANALSPDQALAALYDALRVFRSSCLSES--.............PDKK....------CPNNA....EELV.EKARYEVEKITELLLDSHRAEegLRLA...RTAAILALG-r.....................................
A0A0U3ED29_9CREN/13-115             ..vlhy-----YV..CNKDFSVVDRLANSINPSVALQTLYDAVRNIESIFLSEGKK.............KEEL....CSTVKTLVKNEeldcGKVI.SIAKVEAESIAKLIKESFNKD..VMN-...----------llkvisika.............................
A8ABL6_IGNH4/18-126                 .....a-LSY-FAdkEVRQFNIIDRLANAVNEEVALNTLYDAMRTLKTIITSNKVE.............EVRR....FVRKFGELKDEg.grPQYC.YEGKCPA--ECKKVGEECCCDaeALYKlamREVDDLKHSF......................................
#=GC seq_cons                       ......hLAhshl..hoco.ollDRhANALspEssh+sLhDA.Rllpsslspuclt.............ps+c.....shhhlp.pss....pphp.lhGhLPosp-lcpFlctlccD..lhhA...R+sGslAhS.......................................
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