#=GF ID CdiA_helical
#=GF AC PF21483.1
#=GF DE Toxin CdiA-like, helical domain
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Chuguransky S;0000-0002-0520-0736
#=GF SE ECOD:EF15693
#=GF GA 27.00 27.00;
#=GF TC 34.10 36.60;
#=GF NC 26.50 19.80;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF RC Paper describing PDB structure 4g6u
#=GF RN [1]
#=GF RM 23236156
#=GF RT Structural basis of toxicity and immunity in contact-dependent
#=GF RT growth inhibition (CDI) systems.
#=GF RA Morse RP, Nikolakakis KC, Willett JL, Gerrick E, Low DA, Hayes
#=GF RA CS, Goulding CW;
#=GF RL Proc Natl Acad Sci U S A. 2012;109:21480-21485.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This entry represents the helical domain of EC869 CdiA toxin, a
#=GF CC toxin of the Contact-dependent growth inhibition (CDI) system
#=GF CC [1]. EC869 appears to function as a Zn2+-dependent DNAse
#=GF CC degrading the genome of target cells.
#=GF SQ 6
#=GS W1ITV2_9GAMM/82-140 AC W1ITV2.1
#=GS A0A4U0P5H2_9NEIS/693-752 AC A0A4U0P5H2.1
#=GS A0A6B2FNU1_9ENTR/3181-3240 AC A0A6B2FNU1.1
#=GS A0A443IDC5_9GAMM/376-434 AC A0A443IDC5.1
#=GS A0A6I6EH87_9GAMM/3018-3077 AC A0A6I6EH87.1
#=GS A0A2S0PFV5_9NEIS/1-32 AC A0A2S0PFV5.1
W1ITV2_9GAMM/82-140 MRNEDAKAYVAYWNAIDIAKVDMNSPSWAKFATFAADPENQALLVGGGLLTKDLIK----att
A0A4U0P5H2_9NEIS/693-752 MTMQEAKDFILQENGKDLAMIDQNSPGWMKFVTFVSDPENQVLLVSLGAGAKSLVQWAKA...
A0A6B2FNU1_9ENTR/3181-3240 MTSDEAKAYVQQWNGQDLVNIDVNSAAWMSFASYASDPENQAALASLGMLGKDLIAIAKN...
A0A443IDC5_9GAMM/376-434 MTSDEAKAYVQQWNGQDLANIDVNSPGWTKFAAFASDPENQAMVGSLGLLAKELGA----aai
A0A6I6EH87_9GAMM/3018-3077 MRDDEAKAYVQYWNSQDLTKIDVTTPDWVKFATLVADPENQAMLLSGGLVTKELVQLAR-s..
A0A2S0PFV5_9NEIS/1-32 ----------------------------MSFVAFVGDPENQLALASLGNAGKELVKLAR-s..
#=GC seq_cons Mps-EAKAYVt.WNupDLspIDhNSPuWhKFAoFsuDPENQAhLsSLGhluK-LlphA+.u..
//
