#=GF ID   CgtA
#=GF AC   PF06306.15
#=GF DE   Beta-1,4-N-acetylgalactosaminyltransferase (CgtA)
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_12320 (release 9.0)
#=GF GA   21.00 21.00;
#=GF TC   21.60 21.10;
#=GF NC   20.90 20.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0110
#=GF RN   [1]
#=GF RM   10660542
#=GF RT   Biosynthesis of ganglioside mimics in Campylobacter jejuni
#=GF RT   OH4384. Identification of the glycosyltransferase genes,
#=GF RT   enzymatic synthesis of model compounds, and characterization of
#=GF RT   nanomole amounts by 600-mhz (1)h and (13)c NMR analysis. 
#=GF RA   Gilbert M, Brisson JR, Karwaski MF, Michniewicz J, Cunningham
#=GF RA   AM, Wu Y, Young NM, Wakarchuk WW; 
#=GF RL   J Biol Chem 2000;275:3896-3906.
#=GF DR   INTERPRO; IPR010446;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several
#=GF CC   beta-1,4-N-acetylgalactosaminyltransferase proteins from
#=GF CC   Campylobacter jejuni [1].
#=GF SQ   41
#=GS A0A077DI38_9BURK/1-260   AC A0A077DI38.1
#=GS A0A3D8IAU3_9HELI/4-70    AC A0A3D8IAU3.1
#=GS A0A3A1YRE5_9GAMM/25-203  AC A0A3A1YRE5.1
#=GS A0A4U8T4F2_9HELI/28-326  AC A0A4U8T4F2.1
#=GS A0A1G7C3I4_9FLAO/2-268   AC A0A1G7C3I4.1
#=GS A0A3A1YIY7_9GAMM/23-280  AC A0A3A1YIY7.1
#=GS A0A017H6L7_9FUSO/21-313  AC A0A017H6L7.1
#=GS A0A3A1Y2L6_9GAMM/81-368  AC A0A3A1Y2L6.1
#=GS A0A0F5IVB9_9BACT/2-214   AC A0A0F5IVB9.1
#=GS A0A1J4L1X5_9EUKA/17-269  AC A0A1J4L1X5.1
#=GS A0A848C726_9FUSO/43-92   AC A0A848C726.1
#=GS A2ES01_TRIV3/55-326      AC A2ES01.1
#=GS A0A2W6MXW6_9HELI/1-332   AC A0A2W6MXW6.1
#=GS A0A3A1Y634_9GAMM/19-134  AC A0A3A1Y634.1
#=GS A0A0F5IQ00_9BACT/30-167  AC A0A0F5IQ00.1
#=GS V8C6X7_9HELI/1-233       AC V8C6X7.1
#=GS A0A1J4K973_9EUKA/91-355  AC A0A1J4K973.1
#=GS A0A848C1P3_9FUSO/6-210   AC A0A848C1P3.1
#=GS A0A0F5IVN1_9BACT/13-167  AC A0A0F5IVN1.1
#=GS A0A4R1B767_9ACTN/15-138  AC A0A4R1B767.1
#=GS A0A3D8J9P7_9HELI/11-288  AC A0A3D8J9P7.1
#=GS A0A377I163_HAEPH/27-296  AC A0A377I163.1
#=GS A0A268U4H8_9HELI/63-323  AC A0A268U4H8.1
#=GS A0A4U8U832_9HELI/1-314   AC A0A4U8U832.1
#=GS A0A2A2GT77_9HELI/31-310  AC A0A2A2GT77.1
#=GS A0A1B1U451_9HELI/1-236   AC A0A1B1U451.1
#=GS A0A268TFM0_9HELI/26-203  AC A0A268TFM0.1
#=GS A0A6L5WFX5_9PROT/9-294   AC A0A6L5WFX5.1
#=GS A0A316GFH7_9RHOB/17-135  AC A0A316GFH7.1
#=GS A0A848BYE2_9FUSO/35-100  AC A0A848BYE2.1
#=GS A0A4V6I6J8_9HELI/45-354  AC A0A4V6I6J8.1
#=GS Q0P9B1_CAMJE/5-311       AC Q0P9B1.1
#=GS T1DW24_9HELI/1-334       AC T1DW24.1
#=GS A0A3D8ICJ4_9HELI/13-291  AC A0A3D8ICJ4.1
#=GS A0A329ZEG3_9HELI/10-294  AC A0A329ZEG3.1
#=GS A0A3A1Y7U5_9GAMM/14-167  AC A0A3A1Y7U5.1
#=GS H1D4I4_9FUSO/1-243       AC H1D4I4.1
#=GS D3UIK9_HELM1/5-321       AC D3UIK9.1
#=GS A0A268U4P3_9HELI/30-282  AC A0A268U4P3.1
#=GS O25005_HELPY/100-376     AC O25005.1
#=GS A0A1J4JB63_9EUKA/1-185   AC A0A1J4JB63.1
A0A077DI38_9BURK/1-260              ...........................................mr------------------------------..-----------------------------------.--.--...-----------.----QPVDAWAFMRVCDEMR.TLPACLNSILPVIKKGVIAYNP.....S.....E.....DPEEEkFILDFCQKN...T.....GFI......P.FKY......D...Y...QIipa....gsrE.......Y.L...T.....NT.......E......R.....ER...H.L...D.TYYNA....AL.DQIP.N.........GEWMIKIDADQIY.DTEK..LAR.LL....SMV.-DERQI.VSIARMNLN.V...V...EG..K..LHLYAQT..P--.-.Y..VDP..CD.HWLLkKVSELRFKM.YIT..D.A......D....DSNFE.AYEL...---.LEFPQ.SFC-.K.KY....GL.Q.I-V.HTQLITWHFPLLKRHRR...S--.LSLPSVPLERY.KEV.LD..IE-.A.NHVTLEMVDK-----------dyvisflrkv...................................................................................................
A0A3D8IAU3_9HELI/4-70               ..........................................fyi---RRFFVKILCWFIPTKKLRLKLNAYFGFgnKKVLLDEIDSNIPIKDK--INKIN-----------.--.--...-----------.--------------------.----------------------.....-.....-.....-----.---------...-.....---......-.---......-...-...--..........-.......-.-...-.....--.......-......-.....--...-.-...-.-----....--.----.-.........-------------.----..---.--....---.------.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------plsflssykekln................................................................................................
A0A3A1YRE5_9GAMM/25-203             ................................dqtvqqddfrklq------------------------------..-----------------------------------.--.--...-----------.----TKVEAYALIPVYQEAV.TLSASLETIKQAFTQGVLVYAPppvgvQ.....A.....DQSLE.IATAFVEEN...P.....GFK......L.AIY......P...S...PI..........V.......P.Q..hN.....P-.......-......-.....--...-.-...-.-----....--.----.-.........-------------.----..---.--....---.------.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------wlaeymyeggfsvywlyhnffnfgfvqlqeliklagheeaawiavldpqtiydskgldsfiaqlptlgqtydawrldacalafnhesmf....................
A0A4U8T4F2_9HELI/28-326             ...................................qfieskrnhk------------------------------..-----------------------------------.--.-L...HNGYFDFDPAA.KNPKSPLNPWAWVRVKNEIH.TIKACLESILPAFQRGVIGYND.....C.....D.....DGSEE.FILDFCRKY...P.....SFI......P.IKY......P...Y...SV..........T.......L.K...D.....PP.......T......M.....QN...K.L...Y.FYLTY....IE.KFIP.E.........DEWILKIDCDHIH.DAAK..LYK.SF....YLI.HDHQSC.IFYGRIHIH.K...F...DN..E..LYIQKYD..NGF.I.I..-EG..GD.QLLI.QRKHWWHIE.DLV..SdKgevvamS....KDKWK.KSEL...DDF.LAKEK.MYKN.Q.EFgmiaNM.D.FIY.YTEINNWHFPYIKDFRA...NKA.SEQEWVKLDDF.IES.NK..DLI.N.TRIDSKMLDKDYILSLYN---rfa..........................................................................................................
A0A1G7C3I4_9FLAO/2-268              ...........................................gk------------------------------..-----------------------------------.--.--...-----------.KYRKQPVEPWAFIRVKNEII.TIEACLNSILPVITKGVIGYNP.....S.....D.....DGTEE.FIEDFCKKN...P.....GFI......P.FKY......D...H...EV..........L.......Q.P...K.....DK.......Ryl..hlEsv.piEQ...R.L...D.TYYNA....VF.DKIP.N.........GEWFIKIDCDHIY.DTKK..LSK.LM....YLP.ANDNDV.ICLPYLNFH.Y...E...KR..RegKFLALLK..QI-.P.L..KQH..RD.HWIL.KKTEE-LKF.II-..K.-......H....NPDYK.NKG-...---.--DDI.AWEW.LsGY....QN.H.NLM.DTNVICWHFPFLKSYRR...IF-.--PEIISVQEY.ISM.MN..SRD.K.YLIPRDMLSEQK---------ilnevkkfr....................................................................................................
A0A3A1YIY7_9GAMM/23-280             .........................................yydc------------------------------..-----------------------------------.--.--...-----------.----EPIEPYAYIRFSNEAI.TLKSCLESIVPYIKKGIICYNEplpgiS.....D.....DGSLA.IAQEFVAKN...P.....GYK......L.VRY......P...F...PV..........I.......F.H...N....mPRyydiifsG......A.....TN...K.LwllY.AYSEY....AM.LYLK.RiaqkngdydKAWVFKIDADHIY.SAKL..LEY.TV....LKS.QLYY--.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------kqkgythswlykanvlqdlrendlpqqgqepwflsmvngydhffskldmmaphvmriingvhgteeekrrktqafelprfkpqssanndqvflnsfhffmeklyhyqkh
A0A017H6L7_9FUSO/21-313             .....................lkkiviilrkkidtqmqwnyrklg------------------------------..-----------------------------------.--.--...----------V.KYREEPIEIWAFVRAKNEIK.TIESCLNSILPVIQKGVIGYNK.....Lke.eeD.....DGTEA.FILDFCKKN...P.....GFI......P.FQY......E...H...EV..........I.......P.A...N.....DMry..qdiSa...ipV.....EN...R.L...D.TYYNA....VL.SKLP.K.........NIWMMKIDCDHVF.DTEK..LAQ.LP....YLI.KEDKDM.LSFTRMNLH.Y...E...NK..Q..LFFIN--..-IY.T.I..AAP..DD.WLLL.KNTNLVFKF.S--..-.-......-....-SGYK.ENGS...FFA.WEYLEnETED.L.FF....QR.K.IYY.-TDLISWHFPFMKIGKC...L--.ERRYFTPFSDF.EIS.PK..LKK.K.FHISEDMLDE-----------trilefcknfk..................................................................................................
A0A3A1Y2L6_9GAMM/81-368             ..................................tvtskeldqqa------------------------------..-----------------------------------.--.--...-----------.--------VYALIRFSNEVV.TLKQSLNSLLPAVTKGVLITHP.....T.....AdglqdDGSLQ.VAAEFVQQN...P.....GFS......L.VIY......P...H...PVyhen..hpiyQ.......E.Q...E.....KI.......K......R.....EN...Y.L...D.TFTNFgieaLK.SLAE.Kng.....dtDPWVFKADADQIY.DASL..LSE.QFeqilAVP.SNHIKV.NYFVKLDLH.Y...A...PEtdT..LYYLRTKirSTN.F.L.vKAKylHT.GMVI.EED--KAKE.VYFfeD.Q......Q....TDKFT.FKQS...LKG.LGNFF.KYRF.M.HK....DK.R.NSF.KEGVNNH----------...---.-----------.---.--..---.-.---------------------gkyaslseaqryalhtmreipanytgflnsihfkylkhvh.....................................................................
A0A0F5IVB9_9BACT/2-214              ..........................vgyynsedylvdmsflkke------------------------------..-----------------------------------.--.--...-----------.----RPIGVSGLLRVKNDAE.FLSDCIDSCITALDELIICYQD.....C.....T.....DNAPD.LIRQKQRQY...P.....DKI......K.VYYy...apPvfcHgltEE..........Etr...daF.S...L.....PD.......T......S.....VH...K.L...C.NYYNY....TL.SKA-.T.........YRYAMKIDSDQIY.FAEK..LKR.FC....DAY.RKEGMVrISFGNYLVK.F...Y...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------akiyriavrkcpalfkvdllslipgvrsmvdkqyeiyllkeiinnkya.............................................................
A0A1J4L1X5_9EUKA/17-269             .........................fffhsnkdnlmksyffifes------------------------------..-----------------------------------.--.--...-----------.------ISPYGFFRIQNEQP.TLVPFLKSIENSIFRGVIVYLE.....S.....Y.....DQTEK.LLFEFVKSH...P.....YFQ......I.FKY......P...F...LV..........K.......R.K...N.....RT.......R......I.....EE...R.I...D.FFYNF....VL.SKIP.S.........FSWFLKLDADNIY.SSKS..LFE.IF....RIP.IKDNDM.VCIPYLNIY.C...N...TS..N..QIPYLIF..NGNkT.V..YNV..CD.HFML.KKFNLYFE-.L--..-.-......-....-----.-G-S...KTN.DQSCE.VLRM.K.EG....RN.K.IYV.--SIQALHFPIQKKHRN...YMI.GK---------.---.--..---.-.---------------------akianiiidnkvspkfdnihcpkil....................................................................................
A0A848C726_9FUSO/43-92              .........................................knnk------------------------------..-----------------------------------.--.--...-----------.-----SVEPWAYIRVRNEAS.TLKECLNSIIPVIKKGIVGYND.....C.....T.....DGSEE.I--------...-.....---......-.---......-...-...--..........-.......-.-...-.....--.......-......-.....--...-.-...-.-----....--.----.-.........-------------.----..---.--....---.------.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------f............................................................................................................
A2ES01_TRIV3/55-326                 .................................dgyaplcyrgtq------------------------------..-----------------------------------.--.--...-----------.----QSVDPWAFIRVKDEIN.TIEASLNSLIPALKKGVIGYVN.....S.....T.....DGTNK.VILNFCRQH...P.....TFI......P.IKY......D...Y...DV..........I.......P.A...NdelyfQK.......Y......D.....AN...RaL...D.SYYNY....VY.KFIP.D.........NEWLIRIDADQIY.DTEK..LYM.LT....FLP.DNDIEA.IPIFRINLH.V...D...DG..I..LMILKNG..YGP.F.S..Y-V..ND.QWLL.KKTNGSGFT.MHI..D.-......-....-N---.----...--N.--SRE.AWEL.L.YP....AP.P.TNT.QTDIIAWHFPFLKHWRR...---.-----------.---.--..---.-.---------------------lqddshhdsfdkvkripfgqnakilarlshlhmdedmidenrvkellfry...........................................................
A0A2W6MXW6_9HELI/1-332              ......................mfefylrkflaeffsafalnknt----------------KRKIRQKFSDCHI-..-FIPRNQLDSYIPSDILQRITENSNEDFIQKNR-I.SD.GK...HYGFFSLDQKA.SNPKSKLNPWAFIRVKNEAK.TLKFSLESMLPAIQRGVIGYND.....C.....T.....DGSEE.IILDFCKKF...P.....SFI......P.IKY......P...H...EV..........Q.......M.I...N.....PQ.......K......E.....EN...K.L...Y.KYYEY....VA.NHIP.K.........GEWFIKLDVDHIY.DAKK..LYK.QF....YLP.LKSYDA.LFLSRADFH.V...Y...NN..R..VYIGN--..YG-.-.L..HEA..SD.QPLM.KNQAISFQQ.R-V..E.-......I....KD---.----...-N-.--QSL.YYEH.M.KG....KN.S.TYY.RSELCQYHFPYIKQSRG...SLL.PPEDFILLEDF.KKF.NF..D--.T.NKIDPQMLEEDHILKLYHQ--fd...........................................................................................................
A0A3A1Y634_9GAMM/19-134             .....................................regdqqvy------------------------------..-----------------------------------.--.--...-------HDDY.RQREREVEAFALVPFSNNAI.TLKASLESLAQVIKQGVLLYPElppqvA.....A.....DQSIA.IATEFVANN...P.....GYK......L.VKY......P...T...PV..........L.......LpT...N.....PW.......L......E.....QN...-.-...-.-----....--.----.-.........-------------.----..---.--....---.------.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------fyaggvslywlyheflny...........................................................................................
A0A0F5IQ00_9BACT/30-167             ....................................rerlcgvsg------------------------------..-----------------------------------.--.--...-----------.-----------LMRVKDEAR.WVAQSIDSCIAALDELIICYQE.....S.....T.....DGTEE.IVEQKRLQY...P.....DKIrtffyaP.PVY......T...H...NLske...dfqyA.......V.G...L.....PE.......D......S.....VH...L.L...S.NYYNY....TL.-LKA.R.........YRYAVKIDADQIY.FSDR..LKR.--....---.------.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------lcdayrnelqqki................................................................................................
V8C6X7_9HELI/1-233                  .............................................------------------------------..-----------------------------------.--.--...-----------.--------------------.-----MESILPAIQRGIIAYND.....C.....T.....DGSEE.IILDFCAKY...P.....TFI......P.AKY......P...H...HI..........E.......I.H...N.....PQ.......R......E.....EN...K.L...H.NYYNF....AL.SHIP.K.........KQWLIKIDCDHIY.DAKK..LYK.AF....YLP.KSRFDS.VIKPRFDIL.I...R...ER..R..VYIRKLK..HGL.I.Q..D--..-D.FL-F.RGV----DD.WLI..Y.-......-....NNGLD.FVVW...HPNeNSKHL.FFET.L.TC....RN.RrRNI.CTELNNYHFPFVKNSRAgfgDDW.IKGAF-LLDEI.CQS.P-..-LV.G.TRIDPKLLNKDKILAIY----dsf..........................................................................................................
A0A1J4K973_9EUKA/91-355             .........................................vfek------------------------------..-----------------------------------.--.--...-----------.------LAPYGFMRIRSEQD.TLRPFFSSIEGAIFRGVIVYIE.....S.....T.....DDTEK.ILFDFVKTH...P.....YFS......I.YKY......P...Y...IV..........K.......R.K...N.....IT.......I......L.....EE...R.L...D.YFYNF....AL.SKIP.K.........NAWFIKLDADNIY.SSES..LLK.VM....SIP.KNDNEL.ICLPYLNMY.C...NittKT..P..FFLYHDG..---.I.V..KNV..CD.HWLL.KNVGCYF--.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------eignkadnssaellitrrgikkirgnvqalhfpfqksrrasllkkerlsnmyieneespiidkckcdkslcnynkfyqacndiskqmdesynknlelqn..........
A0A848C1P3_9FUSO/6-210              ..........................................rrn------------------------------..-----------------------------------.--.--...-----------.--------------------.----------------------.....-.....-.....-----.-FLEFCSKN...S.....GFI......P.VKY......P...H...TVfd......fkD.......E.R...N.....GKi.....gN......E.....EN...K.F...A.TCCNY....YL.SFIP.K.........NEWLIKIDCDHIY.DSEK..LKK.IL....KII.TNDKDC.IILPKLNIGeI...K...DN..K..VYLLKS-..--R.V.F..DET..DD.HWII.KNNNLKFKT.IFI..K.-......-....-DHWV.----...---.-----.--EY.L.PL....KG.L.NKK.FTIVNNWHFPYIKKRR-...NEI.-KEEMIELSEW.IKN.NK..EII.G.KEISKDMLESNKIREILKN--fe...........................................................................................................
A0A0F5IVN1_9BACT/13-167             .......................plcskgaynsadyyvdmsflkk------------------------------..-----------------------------------.--.--...-----------.---ERPIGVSELLRVKNDAE.FLTDCIDSCIGALDELIICYQE.....C.....T.....DNAPN.IIHEKQQQY...P.....DKIkayfyaP.PVY......C...H...NL..........TdeelayaF.S...L.....PD.......D......S.....VH...K.L...C.NYYNY....TL.SKA-.T.........YRYAMKIDSDQIY.FTEK..L--.--....---.------.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------klycdayrree..................................................................................................
A0A4R1B767_9ACTN/15-138             ............................eyairwnwvtepsssgf------------------------------..-----------------------------------.--.--...-----------.---------TAVLRVKNEAR.SLPWVLPGILRSVQKTIVVDNN.....S.....T.....DRTAE.LAQEIAEQMgleE.....SLQ......V.LSY......P...F...EV..........S.......R.C...G.....PE.......H......-.....--...-.-...-.-----....--.----.-.........-------------.----..---.--....---.------.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------lmtypdsvhsltyfynwsfshvrtryalkwdgdmvl.........................................................................
A0A3D8J9P7_9HELI/11-288             ........................krgyfffnnllfywyrkkinn------------------------------..-----------------------------------.--.--...----------P.THPKSPLNPWAFIRVCNEKD.TLEQSLNSIVGAISRGIIVYNE.....C.....D.....DGSDE.IIKKFCAKH...K.....GFI......Y.AEY......P...Y...KV..........A......rV.R...H.....YE.......G......El..ktKK...S.L...G.DYYNF....AL.SFIP.Q.........NEWLIKIDTDQIY.DAKK..LKE.SF....NLI.KHQNDI.VFYFRINLH.I...F...DQ..R..IYLQKDS..P--.-.I..FDP..KD.HWLI.CNQRLFFVD.SI-..-.-......-....--QWE.KD--...-NE.VFYWE.SLCI.P.FV....-Y.R.-GF.DARLNTWHFPLLKSSRR...EGA.KIQDFIPLKNY.KEI.IS..QEY.L.DKIDEDMLDEQRILNFF----dkk..........................................................................................................
A0A377I163_HAEPH/27-296             ...................................vtekmqklys------------------------------..-----------------------------------.--.--...-----------.--KREPIKPYAFIRLHNEIK.TVDIALKSVLPALKGGVIGFHS.....C.....S.....DGTKE.YVIEFCKKY...P.....QFI......P.VEY......P...Y...DV..........I.......P.S...G.....DK.......RymnddfD....iNS...R.L...D.SYYNF....IW.DKLP.K.........DEWIIKIDGDHIW.NIEV..LES.LC....RLP.IRKTDC.IILSRINLH.C...D...NG..K..CYIHRKY..P--.-.I..MEG..GD.SWIL.YNHNVRF--.-LF..N.R......-....----G.WNNG...HFF.AYERL.---P.L.PR....KE.R.KKI.LGICSNWHFPIVKN-RR...DDF.KKDDWVLLKDFdIKE.YIkrNKM.D.GRIQDEMLDEKNILNAF----nsfn.........................................................................................................
A0A268U4H8_9HELI/63-323             ........................aiwgcartydlsfklrlkgfr------------------------------..-----------------------------------.--.--...-----------.-KVKKPIKPYAFIRVCNEIP.TLKVSLESIA-FLERGIIAYND.....C.....T.....DGSKE.VILEFCKQH...E.....GFK......A.YEY......P...Y...HV..........K......pIkQ...E.....GR.......Sf...gkD.....YK...E.L...Y.EYYNF....AL.DKIP.K.........DEWLLKIDVDQIY.LQDI..TEE.SF....KYV.EYENDI.VFYPRVNLH.V...I...DD..E..VLVGKDV..P--.-.L..SDV..DD.HWLI.FNHNLSFKK.F--..-.-......-....-----.--VD...RNF.VMEIL.NLPH.T.KL....--.-.NYI.KSTINSFHFPFLKKQRF...TS-.DKSRFLSLEEF.KDR.YK..ND-.-.---------------------rasivadnhlpv.................................................................................................
A0A4U8U832_9HELI/1-314              .........................................msqg------------------------------..--IHLQTLDSLTPTNVLTQINNV------WTYKAT.MGgGG...IPPLYQFDDNA.KDAKSPLNPWAFIRVKNEAA.TLRASLDSILPAIQRGVIGYND.....C.....T.....DGSEA.IILDFCKQN...T.....GFI......P.VKY......P...Y...EV..........M.......L.E...N.....PQ.......H......E.....YN...K.L...H.CYYRF....VL.EHIP.K.........DEWLIKIDVDHIY.NAKI..LFQ.TF....YLA.QTQKHA.IIYPRINFL.V...R...KE..QvvYKIYVQN..NGV.SgF..IDG..YD.QLLV.CNRGIDFIE.RKT..S.-......-....-KAAQ.WIDK...DNY.ENILY.SEQQ.V.VP....KD.I.IYI.HAPLMQWHFPAIKQRRQ...DFS.KHLDTMTLQTF.KKH.NK..HLI.S.LKIPSFMLEEELIESIYKQ--fn...........................................................................................................
A0A2A2GT77_9HELI/31-310             ................................pnsledlqakakl------------------------------..---------------------------------AH.TK.VR...HKGYFELDPDS.SNPKSPRNPWAYIRVKNEAH.TLRASLYSILPAIQRGVIGYND.....C.....D.....DGSEE.IILEFCTAF...P.....SFI......P.VKY......P...Y...SV..........D.......I.Y...E.....PQ.......K......E.....EN...K.L...Y.AYYNY....VL.SVIP.E.........NEWFTKIDIDHIY.HSQK..LYK.SL....YLL.RKPWEV.LIWNVLDFD.I...S...DN..K..VYVR-DM..KC-.-.-..RRE..YD.HWVC.FRSRIHFRE.AIA..A.-......-....-----.WNGV...DSR.KGSFE.VCLL.P.TI....KR.C.I--.LPELTNWHFPFIKDSRK...IAV.KNHKWLLPKEW.---.HS..PEI.G.TMIDPIMLDSTL---------ieelckdf.....................................................................................................
A0A1B1U451_9HELI/1-236              .............................................------------------------------..-----------------------------------.--.--...-----------.--------------------.--------MLPAIQRGVIGYND.....C.....T.....DRSEE.IILDFCQKF...P.....NFI......P.IKY......P...H...EV..........I.......L.E...N.....PP.......K......L.....EN...M.L...H.SYYNF....VL.QAIP.Q.........NEWIIKIDVDHIY.DAQT..LYK.TF....YIP.TLSNHL.VIYPRINYI.I...D...ND..E..IFIQKSE..DMG.F.I..D-G..WD.QWLI.CNQNLEF--.-NI..R.K......T....SKNAQ.WIEE...GNF.SQTL-.FTEV.L.DY...pPN.S.VWF.QAPLMQYHFPAVKQRRN...DFV.RHLDLMTLEEF.SRI.HT.pKRI.D.SHIAHKFISKEMIAQAYQK--fs...........................................................................................................
A0A268TFM0_9HELI/26-203             ...................................pfailsseik------------------------------..-----------------------------------.--.--...----------K.LDDPRPLGISGHLRAKNEAN.TIGLSIETCIDGLDELVITVQP.....S.....D.....DNTYE.ICQEKLKKY...P.....DKI......K.LFYytpevlP...W...NNsh.....cadR.......T.K...E.....LN.......S......D.....NQ...S.I...H.NYAHY....CNySFVKiT.........YKYCMKIDADQIY.FTSK..LK-.--....---.------.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------eireailaadcyakpkrnifhkiagrlcrkfynilsskls.....................................................................
A0A6L5WFX5_9PROT/9-294              ..............................dvkfmpckdrsdgls------------------------------..-----------------------------------.--.--...-----------.----------GFIRCKNEGE.FLEQVIDSWIDLVDELIVVFND.....S.....S.....DNTEE.ILTNSFKKY...P.....QKL......KaYHY......L...P...KV..........F.......S.QgsdN.....FK.......E.....lE.....EDdyqS.L...V.NYYNF....TL.SKTT.K.........-KWALKIDGDIIL.DKEKipLIK.EC....FSK.LKDNEF.IKLSGINII.M...Q...NS..K..IYCLSES..I--.F.C..GLN..GDlCIFK.MSDEIKFKK.GKT..C.E......Y....L-NFP.KKYT...FYS.DENFK.VNNS.L.TA....YY.H.MKF.QKKDFGFGVYDFKNNKN...SNY.YPKTWIFIVFS.RLI.LL..DEI.F.KKYDIKMS-------------dplefinfnknysgykkefi.........................................................................................
A0A316GFH7_9RHOB/17-135             ....................................paerlpgvs------------------------------..-----------------------------------.--.--...-----------.----------AFMRIRNGAD.FLEATIRSHIDAYDEIVAVYNQ.....C.....T.....DATPD.ILDRLAGEY..gPrlrvvHYL......P.RVH......P...Ag.sEG..........H.......A.S...T.....PP.......S......S.....PQ...S.L...V.TYYNC....A-.LAMT.R.........HQWAVKLDDDHL-.----..---.--....---.------.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------aipeal.......................................................................................................
A0A848BYE2_9FUSO/35-100             ...................................iegltriyii------------------------------..-----------------------------------.--.--...-----------.--------------------.----------------------.....-.....-.....-----.---------...-.....---......-.---......-...-...--..........-.......-.-...-.....--.......-......-.....--...-.-...-.-----....--.----.-.........-------------.----..---.--....---.------.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.---GNNYHFPYIKNWRN...KI-.-EEEQIGLNGW.ISQ.NE..ELI.N.KKIPRDMLNENKILEIYKKF-r............................................................................................................
A0A4V6I6J8_9HELI/45-354             .............................kpytlqslkalsldtl------------------------------..------------------------------LNKKK.GG.GGanrHYGFFRFDSKA.NNPKSPLNPWGYIRVKNEAR.TLRASLDSILPAIQRGVIGYND.....C.....D.....DGSEE.IILEFCQTY...P.....SFI......P.IKY......P...Y...SV..........E.......I.K...N.....PK.......K......E.....EN...K.L...Y.YYSNY....IL.SFIP.Q.........GEWFIKLDMDHIY.DAKK..LFK.SL....YLL.KKNTDI.LTLSRMDFY.I...Q...WE..E..VYIGKSV..RGY.Y.N..R-A..GD.QTLR.CNLNCKYYErILS..P.K......LqewgDQILKgKPTKiqlEAL.QENYH.SYEAkV.ED....SY.S.RVY.RSELCHYHFPGIKKRRE...G-I.-PQNVLPLKEF.N--.-D..EAI.G.VEIVPKMLEKETILSLYS---rfd..........................................................................................................
Q0P9B1_CAMJE/5-311                  ..............................ykiiaflrllkidkk------------------------------..--------------------LKFDNEYFLNLNKKI.YD.EK...HKGFFDFDPNS.KDTKSPLNPWAFIRVKNEAT.TLRVSLESMLPAIQRGVIGYND.....C.....T.....DGSEE.IILEFCKQY...P.....SFI......P.VKY......P...H...EV..........Q.......I.E...N.....PQ.......S......E.....EN...K.L...H.SYYNY....VA.SFIP.Q.........DEWLIKIDVDHYY.DAKK..LYK.SF....YMA.SKNT-A.VRFPRINFL.I...L...DK..-..IVIQNIG..EC-.G.F..IDG..GD.QLLI.QKCNSVFIE.RMV..S.-......-....-KQSQ.WIDP...EKT.VKELY.SEQQ.I.IP....KH.I.KIL.QAELLQWHFPALKYHRN...DYQ.KHLDALTLEDF.KKIhYR..HRK.I.KKINYTMLDEKVIREILDK--fk...........................................................................................................
T1DW24_9HELI/1-334                  ............................................m-------------CVPSKKMRRKIRRAMAQ.pKIIPLVEIDNVIPKDVLDKIESYDNAFYYKHNSEIlVG.GA...HRGFFELDSKS.KDTKSPLNPWAFVRVKNEAI.TLKACLESILPAIQRGVIGYND.....C.....T.....DGSEE.IILDFCAKY...P.....SFI......P.YKY......P...F...EV..........Q.......I.K...S.....PK.......S......Q.....EN...Y.L...Y.EYYNF....VL.SKIP.K.........GEWLIKIDVDQIY.DAKK..LYK.SF....YIP.KKDYEL.VSYSRLNVG.I...E...NN..K..VYVENGS..SSK.Y.L..LTP..GD.RWLI.KNVYLSFKE.WIV..N.P......E....-ADPK.DFCY...CEV.LGSTR.DGS-.-.--....ML.R.KHY.ATELPCYHFAFIKDYRK..iTDFsHKEHRISLKEF.KKL.NP..DGI.I.GTRDPALLNEEEILKIYR---gfn..........................................................................................................
A0A3D8ICJ4_9HELI/13-291             ..............................disllkklaltahtk------------------------------..-----------------------------------.--.VS...HKGYFDLDINA.KSPKSQLNPWAYIRVKNEAH.TLRASLYSILPALQRGVIGYND.....C.....I.....DGSEE.IILEFCKTF...P.....SFI......P.IKY......P...Y...NV..........D.......I.Y...N.....PK.......N......K.....EN...K.L...Y.AYYNY....IL.SVIP.K.........GEWLIKIDVDNIY.FADK..LYK.SF....YLP.KKAWDI.VFLHFLNVY.Y...D...GD..D..IVINKKT..TNS.-.-..NIQ..GD.HFLC.KNINLYFKE.AKE..-.-......-....--A--.WNGL...DN-.--KIG.YFET.A.KP....HT.N.NAI.YSELNNLHFPYQKDFRK...IKV.KEFEWIKLKDW.ESN.DI..GSI.-.--I------------------dknilksriilelckef............................................................................................
A0A329ZEG3_9HELI/10-294             ..........................................ysi------------------------------..-----------------------------------.YS.CK...HRGYFEFDTNA.KNPQSPLNPWAFIRVKNERH.TLRSSLDSMLPAFQRGVIGYND.....C.....T.....DGSEE.IILDFCKSY...P.....SFI......P.AKY......P...H...SI..........N.......L.E...H.....PA.......N......E.....MQ...K.L...H.SYYNF....VL.SFIP.Q.........DEWMMKIDVDHIY.DAKK..LFA.SF....YIP.KNTYQK.VDYPRIDFI.I...K...DQ..E..IFIQKIP..-GM.F.LgvRDG..EDqCLVL.-RKHIKFKE.RKS..C.-......K....KAMWI.DSTH...TQP.TLFV-.EEQV.L.DP....QL.K.TTY.QADLTQWHFPAVKQYRH...NYI.EHLELLTLEEF.KQL.HK..HTLlG.TKIESYMLEKDFILS------mhqrfc.......................................................................................................
A0A3A1Y7U5_9GAMM/14-167             ....................................elvkehqce------------------------------..-----------------------------------.--.--...-----------.-----DFEPYAYIRFSNEAI.TLKTCLESLVPFFKKGIICYHE.....PlpgikA.....DASLA.IAQEFIAKN...P.....GFR......L.VKY......P...F...HViyhglpgfynY.......I.Y...N.....GI.......S......R.....FW...L.L...H.AYSQY....AL.LHLE.ElarengdydKAWLFKVDCDHVF.SQKL..L--.--....---.------.---------.-...-...--..-..-------..---.-.-..---..--.----.---------.---..-.-......-....-----.----...---.-----.----.-.--....--.-.---.-----------------...---.-----------.---.--..---.-.---------------------eytklcmqlkfkt................................................................................................
H1D4I4_9FUSO/1-243                  ............................................m------------------------------..-----------------------------------.--.--...-----------.--------------------.------NSILPVIQKGVIGYNK.....Lke.eeD.....DGTED.FILDFCKKN...P.....GFI......P.FQY......E...H...EV..........I.......P.A...N.....DMry..qdiSa...ipV.....EN...R.L...D.TYYNA....VL.SKLP.K.........NIWMMKIDCDHVF.DTEK..LAQ.LP....YLI.KEDKDM.LSFTRMNLH.Y...E...NE..Q..LFFIN--..-IY.T.I..AAP..DD.WLLL.KNTNLVFKF.S--..-.-......-....-SGYK.ENGS...FFA.WEYLEnETED.L.FF....QR.K.IYY.-TDLISWHFPFMKIGKC...L--.ERRYFTPFSDF.EIS.PK..LKK.K.FHISEDMLDE-----------trilefcknfk..................................................................................................
D3UIK9_HELM1/5-321                  ...lsqikrcikrnntqqnlmlkdldiltpkevlkaianhskqwg------------------------------..-----------------------------------.--.-G...VPPLYQLDPRA.MDPKSPLNPWAFIRVKNEEA.TLKASLESILPAIQRGVIGYND.....C.....T.....DSSEE.IILDFCNQN...P.....SFK......A.CKY......P...H...EV..........M.......L.E...N.....PR.......K......Q.....EN...M.L...H.NYYRF....VL.SFIP.K.........EEWMIKIDVDHIY.NPAM..LFQ.TF....YIP.QNITHA.VVYPRVNFV.M...Q...EG..E..IYVQNNG..V-H.G.F..IDG..FD.QLLV.YNRGVDFVA.RKT..S.-......K....KNQWI.NNTH...--T.QDTLY.SEQQ.V.TQ....KH.L.CFI.QAPLIQWHFPAVKARRN...AFV.KHLDLLSLEEF.KQK.NK..KLL.G.SKIPDFMLDSQIIHMLYSR--fl...........................................................................................................
A0A268U4P3_9HELI/30-282             ..........................................mlk------------------------------..-----------------------------------.--.--...-KGFWQRNVKGfRKVKKPIKPYAFIRVCNEIP.TLKASLESIV-FLERGVIVYND.....C.....T.....DGSEE.VILEFCKKY...S.....DFK......A.YKY......P...H...KV..........K.......R.P...Y.....AP.......G......EvfpegYK...E.L...Y.EYYNF....AL.DKIP.K.........DEWLLKIDVDQIY.MQDI..TEE.SF....KLI.EYENDI.VCYPRVNLH.V...L...DG..E..VLVSKDI..P--.-.L..SDV..DD.HWLI.FNHNLSFKM.CAN..S.-......-....-----.----...---.-HGVM.EVLV.L.PH....SG.I.RVK.KSSINSFHFPVLKKQRF...VS-.DKSKFFTWEEF.KAR.YK..EDS.S.---------------------klirggyt.....................................................................................................
O25005_HELPY/100-376                ..............................ledrvihptltlpnp------------------------------..-----------------------------------.--.-T...HSGYFDYDKKS.QNPKSPLNPWAFIRVKNEIV.TLEESLFSMLPAIQRGVIGFND.....C.....D.....DGSKE.VILEFCKKF...P.....SFI......P.ISY......P...Y...EV..........M.......L.K...D.....CP.......S......L.....WH...Q.L...Y.HYSNY....TL.SFIP.K.........NEWVIKIDGDHVY.DAKK..LYE.SF....YIP.KSIKEV.VMYSRINFV.V...Q...DF..E..VFVCNSG..DFG.F.L..DAW..GD.QWLF.YNDCEPF-E.---..-.-......-....--IW-.----...---.QHNDD.IYEI.L.KL....KD.K.HHIkDKELMQWHFPLAKK-RR...NAI.VDNDLIPLKEF.KKH.HA..DLI.G.TKIEESMLDEKRILEMYQK--fn...........................................................................................................
A0A1J4JB63_9EUKA/1-185              .........................................mvkr------------------------------..-----------------------------------.--.--...-----------.--------------------.----------------------.....-.....-.....-----.---------...-.....---......-.---......-...-...--..........-.......-.K...N.....LQ.......R......Y.....EE...R.L...D.FFYNF....VL.SKIP.Q.........NAWFIKLDADNIY.SKDN..LQK.LM....EVP.KNDYDI.ACLPYLNLY.CdttY...RV..P..FYIYNG-..-NQ.I.V..KNV..CD.HWLL.KNFGCYFE-.-LV..D.Q......-....-----.----...---.-DDNS.SYEI.L.KT....KEeR.HEI.FVSIQALHFPFQKTRRN...NWA.KGAKMSKIYIR.NKN.-R..PKI.DgTKCSKSLCSYQNLYQ------vckeis.......................................................................................................
#=GC seq_cons                       ...........................................ht............................................................................................p.lpsaAalRlpNEh..TLctsLpSllsulp+GVIsYN-.....s.....s.....Duoc-.llh-Fspph...P.....sFl......s.hcY......P...a...pV..................h.p...s.....sp.......p......p.....pp...p.L.....sYYNa....sL.shlP.p.........tcWhlKIDsDpIY.sscp..Lhp..h....hh..tpp.ph.l.hshhshh.h.......pt.....hhh.....................D.thlh..p.t..h.................................................................h....l.taHFPh.K..+.......................................................hh...........................................................................................................
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