#=GF ID   ChiW_Ig_like
#=GF AC   PF18683.5
#=GF DE   Chitinase W immunoglobulin-like domain
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   ECOD:EUF07772
#=GF GA   27.00 27.00;
#=GF TC   28.20 28.60;
#=GF NC   25.80 26.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0159
#=GF RN   [1]
#=GF RM   27907169
#=GF RT   Crystal Structure of Chitinase ChiW from Paenibacillus sp. str.
#=GF RT   FPU-7 Reveals a Novel Type of Bacterial Cell-Surface-Expressed
#=GF RT   Multi-Modular Enzyme Machinery.
#=GF RA   Itoh T, Hibi T, Suzuki F, Sugimoto I, Fujiwara A, Inaka K,
#=GF RA   Tanaka H, Ohta K, Fujii Y, Taketo A, Kimoto H;
#=GF RL   PLoS One. 2016;11:e0167310.
#=GF DR   INTERPRO; IPR041278;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is an immunoglobulin like domain found in ChiW, a chitinase
#=GF CC   with high activity towards various chitins. ChiW has a
#=GF CC   multi-modular architecture composed of six domains to function
#=GF CC   efficiently on the cell surface: a right-handed beta-helix
#=GF CC   domain (carbohydrate-binding module family 54, CBM-54), a
#=GF CC   Gly-Ser-rich loop, 1st immunoglobulin-like (Ig-like) fold
#=GF CC   domain, 1st beta/alpha-barrel catalytic domain (glycoside
#=GF CC   hydrolase family 18, GH-18), 2nd Ig-like fold domain and 2nd
#=GF CC   beta/alpha-barrel catalytic domain (GH-18) [1].
#=GF SQ   25
#=GS A0A494XWN1_9BACL/1509-1611  AC A0A494XWN1.1
#=GS A0A265Q8P5_9FIRM/1257-1356  AC A0A265Q8P5.1
#=GS A0A5C8LXQ4_9BACL/415-518    AC A0A5C8LXQ4.1
#=GS A0A6I3SLQ9_HELMO/932-1031   AC A0A6I3SLQ9.1
#=GS A0A4R3L511_9FIRM/1378-1477  AC A0A4R3L511.1
#=GS A0A8J2YN16_9BACL/385-490    AC A0A8J2YN16.1
#=GS A0A3S8ZXP8_9BACL/283-390    AC A0A3S8ZXP8.1
#=GS Q188W0_CLOD6/1132-1237      AC Q188W0.1
#=GS Q188W0_CLOD6/892-997        AC Q188W0.1
#=GS Q188W0_CLOD6/1492-1597      AC Q188W0.1
#=GS Q188W0_CLOD6/1012-1117      AC Q188W0.1
#=GS Q188W0_CLOD6/771-876        AC Q188W0.1
#=GS A0A7X3IHA3_9BACL/326-430    AC A0A7X3IHA3.1
#=GS A0A5C8LXQ4_9BACL/297-403    AC A0A5C8LXQ4.1
#=GS A0A6I3SLQ9_HELMO/1045-1145  AC A0A6I3SLQ9.1
#=GS Q188W0_CLOD6/530-635        AC Q188W0.1
#=GS A0A4R2RZF8_9FIRM/447-552    AC A0A4R2RZF8.1
#=GS A0A398CPD0_9BACL/386-490    AC A0A398CPD0.1
#=GS A0A6B8RPK5_9BACL/1052-1154  AC A0A6B8RPK5.1
#=GS A0A8J2YN16_9BACL/266-365    AC A0A8J2YN16.1
#=GS A0A1C0ZY65_9BACL/405-509    AC A0A1C0ZY65.1
#=GS A0A3G9JLG9_9BACL/393-494    AC A0A3G9JLG9.1
#=GS Q188W0_CLOD6/1372-1477      AC Q188W0.1
#=GS Q188W0_CLOD6/650-755        AC Q188W0.1
#=GS Q188W0_CLOD6/1252-1357      AC Q188W0.1
A0A494XWN1_9BACL/1509-1611             ........dtnll-------MSSDTALDSSANSFTLKLTNGT..I.KSGTLTpmQ.D..F.AINGLPVG.FTA.S.AVG.DPAANTVKFTIAGT..ANSPVTSK-VNLSVVLKGASVSTAGLS.DSA--------pitgit.....
A0A265Q8P5_9FIRM/1257-1356             ............k-DKVTLMAPDYRIIDTKNDTWVIDVTVGT..L.KDNITN..N.D..I.IIAGLPKG.LVA.T.V-S.KVSTNAIEIKVSGT..ASTTLTSDT-TIKVKIKGIAVTEPNSV.DS---------deiel......
A0A5C8LXQ4_9BACL/415-518               ..........npi----IRMSS-PETVDAAANTFTLALSKGSksI.KSGALDpsK.D..F.VINGLPAG.VTA.Q.AVG.MPDTNTVVFTLGGT..AASAVI-DPVQLSVVLKASAVPGAV-L.DAEAN------tikl.......
A0A6I3SLQ9_HELMO/932-1031              ..........tsm----VQMAPGNLTVDKTNNRWLLAVDFGT..V.RSSVSN..D.D..L.DVEGLPEG.LTV.T.AVK.-GSGNRIIVTVTGT..LTAPIEKA-QDVSIRVKGSAVQEPDMN.DA---------epvtvt.....
A0A4R3L511_9FIRM/1378-1477             vyleapdgkvprt----------------IKDTWKIKVTTGT..L.KEDITN..N.D..I.VVAGLPRG.LKA.N.VENvDVNENTITIKVSGT..AATKI--EEATVSIRIKGTAVEELNSM.DSE--------dikvfl.....
A0A8J2YN16_9BACL/385-490               .........vdds----AEMGKNHTSISENNATFSLNLHVGQ..I.KDGALD..SsD..Y.AVIGLPTG.LSV.A.AKG.NSKTNIVTFTLSGQ..AKQAVEDDT-ALSVVLKASAVTSGATN.DSDT-------itgiilk....
A0A3S8ZXP8_9BACL/283-390               ..........naa---AITMNADNKTVSSTQNQFKITLSIGT..V.RNGDLA..E.DddY.TIDGLPDGdFTS.T.AVG.SSSDNSITFTLSGT..ADAPITSDRD-LMVVVKGSALENADAYpDSAAI------sgvkl......
Q188W0_CLOD6/1132-1237                 .............TDKQIKMASGDKTVDPSDDTYVLTLTKGT..A.KDGDVK..A.N..V.EVTGLPSG.LDY.T.AEG.DSSANTITITVSGT..ASQAVQTDLDNVSVLVKAGAVSETTAT.DSAANATFEVK...........
Q188W0_CLOD6/892-997                   .............TDKQIKMASGDKTVDPSDDTYVLTLTKGT..A.KDGDVK..A.N..V.EVTGLPSG.LDY.T.AEG.DSSANTITITVSGT..ASQAVQTDLDNVSVLVKAGAVSETTAT.DSAANATFEVK...........
Q188W0_CLOD6/1492-1597                 .............TDKQIKMASGDKTVDPSDDTYVLTLTKGT..A.KDGDVK..A.N..V.EVIGLPSG.LDY.T.AEG.DSSANTITITVSGT..ASQAVQTDLDNISVLVKAGAVSETTAT.DSAANATFEVK...........
Q188W0_CLOD6/1012-1117                 .............TDKQIKMASGDKTVDPSDDTYVLTLTKGT..A.KDGDVK..A.N..V.EVTGLPSG.LDY.T.AEG.DSSANTITITVSGT..ASQAVQTDLDNVSVLVKAGAVSETTAT.DSAANATFEVK...........
Q188W0_CLOD6/771-876                   .............TDKQIKMASGDKTVDPSDDTYVLTLTKGT..A.KDGDIK..A.N..V.EVTGLPSG.LDY.T.AEG.DSSANTITITVSGT..ASQAVQTDLDNVSVLVKAGAVSETTAT.DSAANATFEVK...........
A0A7X3IHA3_9BACL/326-430               ..........lht----VKMANL-REISASDAQFVVTMTTGS..L.KQGELN.pQ.D..Y.EVGGLPAG.LSV.TrAEA.DPQLHQVTFTIGGT..TTADVTSSVE-LGIVIRKSAVSSGAYD.DSR--------tvrgitle...
A0A5C8LXQ4_9BACL/297-403               ........adsni----IKM-SSETALDPNANTVYLTLPYNT..GiKSGVFQ..P.N.dY.TISALPSG.LTA.T.VSG.DPSNNRIAITLSGT..SQTPVTSDV-NLGVVIKASVVTTTGET.LDSPEAT----ivlq.......
A0A6I3SLQ9_HELMO/1045-1145             ............q-DGQIGLAEGNQTVS-SDNTWVLKVTNGT..V.KADLSI..K.D..L.ALSGLPAG.LVV.T.AAK.-GTGDEIVLTVDGT..LEKAL-TEPAQVAVIVKASSLDPATGT.DAG--------pvnvti.....
Q188W0_CLOD6/530-635                   .............TDKQIKMASGDKTVDPSDNTYILKLTNGT..V.KDGDVK..A.N..V.KVAGLPSG.LDY.T.AVG.NRSANTITITVSGT..ASQSIQNDLNNVSVLVKAGAVSGTGAT.DSIANTTFEIK...........
A0A4R2RZF8_9FIRM/447-552               .............TDDIISMNSGNTTIS-ANNSWIINVTAGT..V.KTNISK..D.D..L.LITDLPNG.VTF.T.AAK.DGASNAIIVTLSTTnnANTPLISTLTPVKIVVKSTAVSEANAA.NSN--------eltatlh....
A0A398CPD0_9BACL/386-490               .....aadstvsm--------SDSAAVSSADNSFAITLVNGT..V.SNGPIA..A.S.hF.SISGLPAG.LTF.A.ATG.DG-AKTITFTVGGA..AASGVFNDA-SVSVVIKKEAIVSGATE.DSD--------miggivvk...
A0A6B8RPK5_9BACL/1052-1154             ............i-DASIDMAAGNKTINLSNNTWVINGINGT..V.KEGLNA..D.D..L.IVTGLPNG.LTL.T.AAR.-GEDNKIIITLDGT..ALAAV-TETTNVNIVVKGSAVTENGAT.DST--------glslqln....
A0A8J2YN16_9BACL/266-365               ...........vn--NDVKMGS-DTEVSSSDNTFKIHLTSGQ..V.KDGPIS..T.N..YySIVGLPNG.LTS.S.AVG.NTEDHSITFTIKGT..SDQAVTSNID-LKVSLKASAST-----.-----------gaygdsdaygq
A0A1C0ZY65_9BACL/405-509               .............TDTTVSMSSA-TAVSSADSSFAVQLSKGT..I.KDGLLQ..AtD..Y.SVIGLPSG.LSI.E.ATG.VAAANTVNFRVYGT..AAQPILNDV-NLSVVLKKEAVTAGATQ.DSD--------iisgitlk...
A0A3G9JLG9_9BACL/393-494               .....tlamltst------------KLDPAHSNLCLKLTTGT..P.TEGTID..P.S..LyAIQGLPSA.AQVtT.AVG.NAADKTIMFTIAGD..AIQPVTTDIP-LTVTVKVGAVSEGATQ.DSDVIT-----gftw.......
Q188W0_CLOD6/1372-1477                 .............TDKQIKMASGDKTVDPSDDTYVLTLTKGT..A.KDGDVK..A.N..V.EVIGLPSG.LDY.T.AEG.DSSANTITITVSGT..ASQAVQTDLDNVSVLVKAGAVSETTAT.DSAANATFEVK...........
Q188W0_CLOD6/650-755                   .............TDKQIKMASGDKTVDPSDDTYVLTLTKGT..A.KDGDVK..A.N..V.EVTGLPSG.LDY.T.AEG.DSSTNTITITVSRT..ASQAVQTDLDNVSVLVKAGAVSETTAT.DSAANATFEVK...........
Q188W0_CLOD6/1252-1357                 .............TDKQIKMASGDKTVDPSDDTYVLTLTKGT..A.KDGDVK..A.N..V.EVTGLPSG.LDY.T.AEG.DSSANTITITVSGT..ASQAVQTDLDNVSVLVKAGAVSETTAT.DSAANATFEVK...........
#=GC seq_cons                          ...............t.IcMuSuspTVDsocsTalLsLTpGT..l.K-Gslp..s.s..l.pVsGLPuG.Lsh.T.AtG.cuusNTITlTVSGT..AspuVpoDlsslSVlVKuuAVopssus.DSs...................
//