#=GF ID ChlamPMP_M
#=GF AC PF07548.15
#=GF DE Chlamydia polymorphic membrane protein middle domain
#=GF AU Yeats C;0000-0003-0080-6242
#=GF SE Yeats C
#=GF GA 25.00 25.00;
#=GF TC 25.50 26.30;
#=GF NC 24.30 23.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Family
#=GF RC First identification of the domain
#=GF RN [1]
#=GF RM 15837807
#=GF RT The Chlamydophila abortus genome sequence reveals an array of
#=GF RT variable proteins that contribute to interspecies variation.
#=GF RA Thomson NR, Yeats C, Bell K, Holden MT, Bentley SD, Livingstone
#=GF RA M, Cerdeno-Tarraga AM, Harris B, Doggett J, Ormond D, Mungall K,
#=GF RA Clarke K, Feltwell T, Hance Z, Sanders M, Quail MA, Price C,
#=GF RA Barrell BG, Parkhill J, Longbottom D;
#=GF RL Genome Res 2005;15:629-640.
#=GF RN [2]
#=GF RM 14756775
#=GF RT From the inside out--processing of the Chlamydial
#=GF RT autotransporter PmpD and its role in bacterial adhesion and
#=GF RT activation of human host cells.
#=GF RA Wehrl W, Brinkmann V, Jungblut PR, Meyer TF, Szczepek AJ;
#=GF RL Mol Microbiol 2004;51:319-334.
#=GF DR INTERPRO; IPR011427;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family contains several Chlamydia polymorphic membrane
#=GF CC proteins. Chlamydia pneumoniae is an obligate intracellular
#=GF CC bacterium and a common human pathogen causing infection of the
#=GF CC upper and lower respiratory tract. This domain is found between
#=GF CC the beta-helical repeats (Pfam:PF02415) and the C-terminal
#=GF CC Pfam:PF03797. This domain is excised subsequent to secretion
#=GF CC [2].
#=GF SQ 21
#=GS PMPC_CHLTR/1202-1432 AC O84419.1
#=GS PMPG_CHLTR/520-695 AC O84879.1
#=GS A0A656K9S8_CHLPS/1-97 AC A0A656K9S8.1
#=GS A0A655MY63_CHLTH/292-467 AC A0A655MY63.1
#=GS A0A656K8E3_CHLPS/1-137 AC A0A656K8E3.1
#=GS A0A656K915_CHLPS/4-79 AC A0A656K915.1
#=GS A0A656KDB3_CHLPS/135-312 AC A0A656KDB3.1
#=GS PMPE_CHLTR/460-648 AC O84877.1
#=GS PMPI_CHLTR/425-568 AC O84882.1
#=GS A0A655MWH9_CHLTH/19-162 AC A0A655MWH9.1
#=GS PMPH_CHLTR/515-682 AC O84880.1
#=GS A0A656K8F5_CHLPS/37-175 AC A0A656K8F5.1
#=GS PMPA_CHLTR/499-658 AC O84417.1
#=GS A0A656KBE9_CHLPS/40-198 AC A0A656KBE9.1
#=GS A0A656KAU0_CHLPS/2-95 AC A0A656KAU0.1
#=GS A0A656KBV2_CHLPS/1-85 AC A0A656KBV2.1
#=GS PMPD_CHLTR/1000-1201 AC O84818.1
#=GS A0A656KDC8_CHLPS/84-233 AC A0A656KDC8.1
#=GS PMPF_CHLTR/489-665 AC P38008.2
#=GS PMPB_CHLTR/1226-1416 AC O84418.2
#=GS A0A656KDU6_CHLPS/99-152 AC A0A656KDU6.1
PMPC_CHLTR/1202-1432 ........................................GSLVLKPNTELHVIS..FEQKeGSSLVMTPGSVLSNQ......................................------TVADGALVINNMTIDLSSVEKNgiAEGNIFTPPElriidtttggsggtpstdsesnqnsddteeqnnndasnqgesangssspavaaahtsrtrnfaaaatatPTTTPTATTTTSNQVILGG.EIKL.-IDPNGTFFQNPAL-.RS.DQQISLLVL.......---PTDSSKMQAQ.KIVLTGDI.APQKGYTGTLTLDPDQL...............----..QNGTISVLWKF..............................
PMPG_CHLTR/520-695 ........................................GRIVLREKAKLSVNS..LSQT.GGSLYMEAGSTLDFVt....................................pQPPQQPPAANQLITLSNLHLSLSSLLANnaVTNPPTNPPA....................................................................qDSHPAIIGSTTAGSVTISG.PIFF.-EDLDDTAYDRYDWL.GS.NQKIDVLKLq.....lGTQPSANAPSD--.--LTLGNE.MPKYGYQGSWKLAWDPN...............TANN..GPYTLKATWTK..............................
A0A656K9S8_CHLPS/1-97 ......................................pt---------------..----.---------------......................................----------------------------..----------.....................................................................---PAKVAATTDSQKVTIN.AVNL.-VNTDSNSYENPILS.SS.KPFSAITVI.......--SSSGQTTTAPE.SNPTNYVP.PTHYGYQGNWTVTWAQG...............-SGT..QEQIATLNWE-q.............................
A0A655MY63_CHLTH/292-467 ........................................GRIVLREKAKLSVNS..LSQT.GGSLYMEAGSTLDFVt....................................pQPPQQPPAANQLITLSNLHLSLSSLLANnaVTNPPTNPPA....................................................................qDSHPAVIGSTTAGSVTISG.PIFF.-EDLDDTAYDRYDWL.GS.NQKIDVLKLqlgtqppANAPSDLTLGN--.-------E.MPKYGYQGSWKLAWDPN...............TANN..GPYTLKATWTK..............................
A0A656K8E3_CHLPS/1-137 ...................................mvptv---------------..----.---------------......................................-----EESPDGSITINNLAVNLDSLENG..----------.....................................................................-KVITLAAKGGTGSVTLTG.NLQF.-QDSNQNFYDN-PLL.NK.NFTLNFLDI.......SAPTTDKIHTEGF.NMIPQGAT.GSDLGYQGKWEVTEIKD...............--S-..-----------sgkvsfeikwvsagyiptanrrat......
A0A656K915_CHLPS/4-79 ....................................tkdr---------------..----.---------------......................................----------------------------..----------.....................................................................---TTSYQEDTSSSATISG.PLLL.LNSDNEDPYDSLNLS.SG.INRVSFLYL.......---CDNQEKKITTtDLDIQAINeTDHYGY-----------...............----..-----------..............................
A0A656KDB3_CHLPS/135-312 ........................................GKLVLADKASLSVVS..FDQQsDSILLMDSGTSLSTTdnshatpatvaagaaaaaavvmsttaeassatstttttASVTNQPNDNGSISIKDLHINLGSLTQA..----------.....................................................................GEGAKIDVKGSNGTITITG.HISL.-DDVSGNAYENHDLFnKN.TVTLNLLSL.......STKSESKITSNDL.QLTPRGDA.DPQYGYQ----------...............----..-----------..............................
PMPE_CHLTR/460-648 ........................................GFLCIEDHAQLTVNR..FTQT.GGVVSLGNGAVLSCY......................................KNGTGDSASNASITLKHIGLNLSSILKSgaEIPLLWVEPT.....................................................................-NNSNNYTADTAATFSLSDvKLSL.IDDYGNSPYESTDLT.HA.LSSQPMLSI.......SEASDNQLQSE--.NIDFSGLN.VPHYGWQGLWTWGWAKTqdpepassatitdpqKANR..FHRTLLLTWLP..............................
PMPI_CHLTR/425-568 ........................................GRLVLKDRAVLSAPS..LSQDpQALLIMEAGTSLKTS......................................----------SDLKLATLSIPLHSLDTE..----------.....................................................................-----KSVTIHAPNLSI-Q.KIFL.SNSGDENFYENVELL.SKeQNNIPLLTL.......SKEQSHLHLPD--.-----GNL.SSHFGYQGDWTFSWKDS...............---D..EGHSLIANWT-pknyv.........................
A0A655MWH9_CHLTH/19-162 sesnqnsddteeqnnndasnqgesangssspavaaahtsr---------------..----.---------------......................................----------------------------..---------Trnfaa...........................................................aatatPTTTPTATTTTSNQVILGG.EIKL.-IDPNGTFFQNPAL-.RS.DQQISLLVL.......---PTDSSKMQAQ.KIVLTGDI.APQKGYTGTLTLDPDQL...............----..QNGTISVLWKF..............................
PMPH_CHLTR/515-682 ........................................GELVVTEGATLTTGT..ITAT.SGRVTLGSGASLSAV......................................---AGAANNNYTCTVSKLGIDLESFLTP..----------.....................................................................-NYKTAILGADGTVTVNSGsTLDL.VMESEAEVYDN-PLF.VG.SLTIPFVTL.......---SSSSASNGVTkNSVTINDAdAAHYGYQGSWSADWTKPplapd.....akgmvPPNT..-NNTLYLTWRP..............................
A0A656K8F5_CHLPS/37-175 ........................................GQLIVTNNANLNVLG..LTTE.TGKLTLGSGASIGLL......................................-STTGDNPAAESFTISKLGCDVQSYLNP..----------.....................................................................NFSPASVTTSNNKTITLSG.SLDL.VSENDAELYDN-PLL.QG.ALSFPFATF.......TSNNTDPTTS---.SFNSGPLTvPQHYGYQGVW-------...............----..-----------p.............................
PMPA_CHLTR/499-658 ........................................GTLSIENGAHLIVQS..FKQT.GGRISLSPGSSLALYt...................................mnSFFHGNISSKEPLEINGLSFGVDISPSN..----------.....................................................................--LQAEIRA-GNAPLRLSG.SPSI.-HDPEGLFYENRDTA.AS.PYQMEILLT.......SDKIVDISKFTT-.---DSLVT.NKQSGFQGAWHFSWQPN..............tINNT..KQKILRASWLP..............................
A0A656KBE9_CHLPS/40-198 ........................................GSLVLEKGAHLEAKS..LTQTeGSKIILDQTSSIKVQ......................................----------ENVDIKELWLSLDEFVEP..----------.....................................................................-TAANISSSGAAHTVTVKG.PLGI.-FADQEAFYNHHAL-.AN.NVDQELLQL......aDQDITKISLVDVP.ESVR-ENL.NTHRGYQGSWTVDWKTVpgs........tsggVTTL..GTKTATVHWR-p.............................
A0A656KAU0_CHLPS/2-95 ..................................ivaisd---------------..----.---------------......................................----------------------------..----------.....................................................................-------------------.----.-----PDFYENPEL-.AQ.QLNREFLKV.......SA-TGQVTVS---.NGDATNDKeEAHAGYQGIWKLTWEDS...............PAE-..-----------gsgsakvanlnwqplgyipttadtqsytal
A0A656KBV2_CHLPS/1-85 .......................................m---------------..----.---------------......................................----------------------------..----------.....................................................................---------------TVSG.AIGV.-VDPTGKFYENHKLN.DT.LALGGILLS.......--GKGAVTTTNV-.PSHVVGVA.ETHYGYQGNWSVSWIKD...............-NNSdpKTQTAVFTWN-k.............................
PMPD_CHLTR/1000-1201 ........................................GSLELLNGATLCSYG..FKQDaGAKLVLAAGAKLKILdsgtpvqqghaiskp.......eaeiesssepegahslWIAKNAQTTVPMVDIHTISVDLASFSSS..-------QQE.....................................................................GTVEAPQVIVPGGSYVRSG.ELNLeLVNTTGTGYENHALL.KN.EAKVPLMSFvasgdeaSAEISNLSVSDLQiHVVTPEIE.EDTYGHMGDWS------...............EAKI..QDGTLVISWNP..............................
A0A656KDC8_CHLPS/84-233 ........................................GTLSITGGAILAVQE..FKQF.GGVLNLSPGSMLTSY......................................------NSSGKDVVISNISFGLDAAHSH..----------.....................................................................--LPAEIRS-GNSEIKLSG.SPQI.-HDPDNIFYDNHSLA.SQ.PYQMEIIFK.......---SDKNIHTEKF.VPEEIAVQ.QNTYGYQGVWKFNWSEE...............DSKR..-HKTLRALWI-p.............................
PMPF_CHLTR/489-665 ........................................GTLAIEDDAELEIFNipFTQNpTSLLALGSGATLTVG......................................--------KHGKLNITNLGVILPIILKEgkSPPCIRVNPQdmtq.............................................................ntgtGQTPSSTSSISTPMIIFNG.RLSI.VDENYESVYDSMDLS.RG.KAEQLILSI.......ETTNDGQLDSNWQsSLNTSLLS.PPHYGYQGLWTPNWITT...............----..---TYTITL--nnnssa........................
PMPB_CHLTR/1226-1416 ........................................GTLVLKEKTELHVVS..FEQKeGSKLIMKPGAVLSNQ......................................------NIANGALVINGLTIDLSSMGTP..QAGEIFSPPElrivattssasggsgv.....................................sssiptnpkrisaaapSGSAATTPTMSENKVFLTG.DLTL.-IDPNGNFYQNPML-.GS.DLDVPLIKL.......---PTNTSDVQVY.DLTLSGDL.FPQKGYMGTWTLDSNPQ...............----..-TGKLQARWTF..............................
A0A656KDU6_CHLPS/99-152 ........................................GSLVLKDGVTLEAKK..VTQT.AGSVVMDLGTTLQTP......................................------SSGGETITLTNLDINVASL---..----------.....................................................................-------------------.----.---------------.--.---------.......-------------.--------.-----------------...............----..-----------g.............................
#=GC seq_cons ........................................GpLslpptspLps.p..hpQp.su.l.htsGssLp................................................stt.lslppltlsLsuh.p.....................................................................................ss.hssssssplsloG.plpl...-sssshY-N.sL..ss.p.phslLpl..........sss.spsp...p.sh.sst.sscaGYQGsWphs.t..........................ph.h.W................................
//
