#=GF ID Col-Pyo_DNase
#=GF AC PF21431.1
#=GF DE Colicin/Pyocin-S2, DNase domain
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Chuguransky S;0000-0002-0520-0736
#=GF SE ECOD:EF01808
#=GF GA 27.00 27.00;
#=GF TC 27.80 27.30;
#=GF NC 26.50 25.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF CL CL0263
#=GF RC Paper describing PDB structure 1m08
#=GF RN [1]
#=GF RM 12441102
#=GF RT The crystal structure of the nuclease domain of colicin E7
#=GF RT suggests a mechanism for binding to double-stranded DNA by the
#=GF RT H-N-H endonucleases.
#=GF RA Cheng YS, Hsia KC, Doudeva LG, Chak KF, Yuan HS;
#=GF RL J Mol Biol. 2002;324:227-236.
#=GF RC Paper describing PDB structure 1mz8
#=GF RN [2]
#=GF RM 12441392
#=GF RT Metal ions and phosphate binding in the H-N-H motif: crystal
#=GF RT structures of the nuclease domain of ColE7/Im7 in complex with a
#=GF RT phosphate ion and different divalent metal ions.
#=GF RA Sui MJ, Tsai LC, Hsia KC, Doudeva LG, Ku WY, Han GW, Yuan HS;
#=GF RL Protein Sci. 2002;11:2947-2957.
#=GF RC Paper describing PDB structure 1pt3
#=GF RN [3]
#=GF RM 14962381
#=GF RT DNA binding and degradation by the HNH protein ColE7.
#=GF RA Hsia KC, Chak KF, Liang PH, Cheng YS, Ku WY, Yuan HS;
#=GF RL Structure. 2004;12:205-214.
#=GF RC Paper describing PDB structure 1ujz
#=GF RN [4]
#=GF RM 15034550
#=GF RT Computational redesign of protein-protein interaction
#=GF RT specificity.
#=GF RA Kortemme T, Joachimiak LA, Bullock AN, Schuler AD, Stoddard BL,
#=GF RA Baker D;
#=GF RL Nat Struct Mol Biol. 2004;11:371-379.
#=GF RC Paper describing PDB structure 1v13
#=GF RN [5]
#=GF RM 15190054
#=GF RT Structure-based analysis of the metal-dependent mechanism of
#=GF RT H-N-H endonucleases.
#=GF RA Mate MJ, Kleanthous C;
#=GF RL J Biol Chem. 2004;279:34763-34769.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This entry represents the DNAse domain from colicin/pyocin
#=GF CC bacteriocins, such as pyocin-S2 from Pseudomonas aeruginosa and
#=GF CC colicin E7/E9 from E. coli. This domain has an alpha/beta fold
#=GF CC containing a Zn2+ ion binding site [1-5].
#=GF SQ 79
#=GS A6TI19_KLEP7/648-771 AC A6TI19.1
#=GS A0A2A2HQI4_9GAMM/511-634 AC A0A2A2HQI4.1
#=GS A0A7L9RSD5_9PROT/560-672 AC A0A7L9RSD5.1
#=GS Q87GQ2_VIBPA/744-867 AC Q87GQ2.1
#=GS S2KMV0_HALAF/20-127 AC S2KMV0.1
#=GS B2VB98_ERWT9/514-637 AC B2VB98.1
#=GS A0A1M5YRQ2_9VIBR/441-564 AC A0A1M5YRQ2.1
#=GS S2KM91_HALAF/210-333 AC S2KM91.1
#=GS I4MYA9_9PSED/153-275 AC I4MYA9.1
#=GS A0A509CES8_9ENTR/109-173 AC A0A509CES8.1
#=GS A0A1J0VYR1_9NOCA/1712-1838 AC A0A1J0VYR1.1
#=GS A0A4Q5XAB7_9DELT/429-552 AC A0A4Q5XAB7.1
#=GS D3VLI3_XENNA/3-74 AC D3VLI3.1
#=GS A0A1V9FDB7_9BACT/54-113 AC A0A1V9FDB7.1
#=GS A0A6C2YI70_9BACT/151-274 AC A0A6C2YI70.1
#=GS J8VER2_PSEPU/1-80 AC J8VER2.1
#=GS A0A1G8FEJ5_9VIBR/132-241 AC A0A1G8FEJ5.1
#=GS A0A1G8CGI9_9VIBR/704-826 AC A0A1G8CGI9.1
#=GS A0A1H8EDF3_9ACTN/3580-3704 AC A0A1H8EDF3.1
#=GS A7MTX8_VIBC1/733-856 AC A7MTX8.1
#=GS Q88NA6_PSEPK/630-754 AC Q88NA6.1
#=GS A0A2G9DCY2_9ACTN/2069-2193 AC A0A2G9DCY2.1
#=GS A0A6M8MRR7_9PSED/108-231 AC A0A6M8MRR7.1
#=GS A0A024HC89_PSEKB/350-473 AC A0A024HC89.1
#=GS A0A7L9RTN4_9PROT/133-246 AC A0A7L9RTN4.1
#=GS A0A2G1XFX9_STRCJ/1333-1457 AC A0A2G1XFX9.1
#=GS A0A4S4BNA4_9BACI/2-107 AC A0A4S4BNA4.1
#=GS A0A5Q2K4S2_9ENTR/422-545 AC A0A5Q2K4S2.1
#=GS A0A077LDN9_9PSED/1-110 AC A0A077LDN9.1
#=GS W1DQY5_KLEPN/196-281 AC W1DQY5.1
#=GS A0A2K9PSG6_9FLAO/6-127 AC A0A2K9PSG6.1
#=GS A0A1Y4SVF6_9FIRM/257-379 AC A0A1Y4SVF6.1
#=GS Q87UR4_PSESM/526-649 AC Q87UR4.1
#=GS A9MMY5_SALAR/1063-1194 AC A9MMY5.1
#=GS A0A3N4B9L8_YERPE/1-78 AC A0A3N4B9L8.1
#=GS A0A3M0M9V3_9RHOB/337-461 AC A0A3M0M9V3.1
#=GS A0A3S5D9R2_SALBN/1-112 AC A0A3S5D9R2.1
#=GS A0A1G9NN07_9PSED/145-268 AC A0A1G9NN07.1
#=GS A0A1H3M140_9BACL/304-425 AC A0A1H3M140.1
#=GS A0A554VBD5_9FLAO/761-882 AC A0A554VBD5.1
#=GS A0A5R9QBD0_9GAMM/309-432 AC A0A5R9QBD0.1
#=GS A0A3E0H1T5_9PSEU/1157-1281 AC A0A3E0H1T5.1
#=GS A0A3R8VNI6_9PSED/214-318 AC A0A3R8VNI6.1
#=GS A0A8J7GUC1_9ENTR/163-288 AC A0A8J7GUC1.1
#=GS K6TUC4_9CLOT/2394-2509 AC K6TUC4.1
#=GS I4MVQ3_9PSED/114-237 AC I4MVQ3.1
#=GS A0A1B7K407_9GAMM/481-604 AC A0A1B7K407.1
#=GS A0A1G7HEI6_9FLAO/89-184 AC A0A1G7HEI6.1
#=GS A0A1Y6INM4_9VIBR/424-547 AC A0A1Y6INM4.1
#=GS A0A1R3UQW6_9ACTN/550-674 AC A0A1R3UQW6.1
#=GS A0A0A5HUK2_9BACI/3-76 AC A0A0A5HUK2.1
#=GS I4N884_9PSED/1-111 AC I4N884.1
#=GS PYS2_PSEAE/563-686 AC Q06584.3
#=GS A0A315WYZ4_9PSED/269-392 AC A0A315WYZ4.1
#=GS A0A3S4E8E7_SALBN/1-79 AC A0A3S4E8E7.1
#=GS A0A2S1LQ14_9FLAO/84-179 AC A0A2S1LQ14.1
#=GS A8AJ94_CITK8/451-576 AC A8AJ94.1
#=GS A0A8H9IMQ9_9PSEU/1348-1472 AC A0A8H9IMQ9.1
#=GS A0A7K4ELU5_9PSED/601-724 AC A0A7K4ELU5.1
#=GS A0A5J5G413_9GAMM/14-123 AC A0A5J5G413.1
#=GS A0A066UC02_9GAMM/8-117 AC A0A066UC02.1
#=GS A0A7X6EJT3_9PSED/291-414 AC A0A7X6EJT3.1
#=GS A0A1W2FUC7_9PSEU/1-86 AC A0A1W2FUC7.1
#=GS Q13MM2_PARXL/1-67 AC Q13MM2.1
#=GS A0A8J7FVE1_9CYAN/641-767 AC A0A8J7FVE1.1
#=GS A0A285NN04_9PSED/555-675 AC A0A285NN04.1
#=GS A0A1G5KM92_9HYPH/652-768 AC A0A1G5KM92.1
#=GS A0A5Q0JT95_9FLAO/1595-1717 AC A0A5Q0JT95.1
#=GS Q7N5Q1_PHOLL/433-556 AC Q7N5Q1.1
#=GS A0A177QTE1_9BACT/2-117 AC A0A177QTE1.1
#=GS L0M703_ENTBF/460-585 AC L0M703.1
#=GS A0A553ATJ3_9RHOB/44-167 AC A0A553ATJ3.1
#=GS A0A1H4G7H6_9GAMM/82-207 AC A0A1H4G7H6.1
#=GS A0A1Y6ISU1_9VIBR/304-427 AC A0A1Y6ISU1.1
#=GS A0A1G9FKP4_9PSED/323-446 AC A0A1G9FKP4.1
#=GS A0A0D8ZMX4_9CYAN/2-104 AC A0A0D8ZMX4.1
#=GS A0A663BLV5_9ENTR/163-286 AC A0A663BLV5.1
#=GS A0A7L4XUF0_9ACTN/1388-1512 AC A0A7L4XUF0.1
#=GS A0A7K4EKR1_9PSED/358-479 AC A0A7K4EKR1.1
A6TI19_KLEP7/648-771 ..............................................GTVS.GKGQ..NVG..N..N..WMG..GA.STGDGAPVPSQIADKLRGK.TFGSFDSSRRAFWKAVADDSALSKQFS.E.ADINQMK.AGRAPTAD...FL..ES.V..GKR....VKIELHHEK.EIS.QGG..AVMDVDNIKALTPKNHIETHK......................
A0A2A2HQI4_9GAMM/511-634 ..............................................GVVT.GKGQ..EVT..G..N..WLS..KA.GEELGAPIPSQIADNLRGK.KFNNFDEFRRKFWEEVSKDTELSKQFI.K.SNRDRML.VGKAPKSR...KK..DT.I..GKR....SSFELHHEK.QIS.KGG..EVYNMDNLRVTTPKKHIDIHR......................
A0A7L9RSD5_9PROT/560-672 ......................................nppvlmrg----.----..---..-..-..---..--.THNSAGKVPLEVAQKLSGK.EFSSFDAFRSEFWKTMAE-SSYAKEFK.S.ADIARMQ.KGNAPIVH...LE..QS.L..GSR....ITYELHHRT.PIH.DGG..PVYDLSNLLIVTPKYHKEI--ls....................
Q87GQ2_VIBPA/744-867 ..............................................GVVT.GKGE..DIF..G..I..WLA..DA.GKDLGAPIPSQIADKLRGR.EFSSFDAFREGFWYAVGEDQTLINQFS.R.ANQRLIK.RGRSPFSL...PS..EQ.V..GGR....QRYELHHKE.EIQ.YGG..EVFHVDNLCVLTPKRHISIHK......................
S2KMV0_HALAF/20-127 ..........................................aiyv----.----..---..-..-..---..--.SQELGAPIPSQIADRLRGR.EFSTFADFRRAFWMEVANDPTLSEQFS.I.INRQRIA.EGKAPVAI...SS..EQ.V..GGR....ERFELHHAH.EIQ.HGG..AVYDMDNLRH-----------clksrrama.............
B2VB98_ERWT9/514-637 ..............................................GKVS.GKGK..NVG..D..G..WLN..KA.GQELGSPVPTQIADKLRGR.KFASFDAFRKAFWQEVSKDPALGKQFN.N.QNRTNIK.NGKSPFVP...ES..ER.V..GSR....QRYELHHVK.QIK.DNG..AVYDVDNLGIMTPRRHIDIHK......................
A0A1M5YRQ2_9VIBR/441-564 ..............................................GVVT.GQGE..DMT..G..I..WLE..KA.GEELGSPVPSQIADKLRGQ.RFSSFDKFRKAFWLAVSEDRQLKTQFI.G.NNIDRMS.KGYAPRAR...KK..DS.V..GKR....QSFEIHHVE.EIQ.HGG..KVYDVDNLRVLTPQRHIDIHK......................
S2KM91_HALAF/210-333 ..............................................GTAT.GQGE..EVT..G..R..WLE..QT.SQELGAPIPAQIADRLRGR.EFSTFADFRRAFWMEVANDPTLSEQFI.L.PNRIIMA.DGKSPYTI...SS..ER.V..GGR....ERFEIHHTH.EIQ.HGG..AVYDMDNLRVMTPRQHIDIHR......................
I4MYA9_9PSED/153-275 ..............................................GTVT.GQGK..DVT..G..I..WLA..GA.TSGLGAPIPTEIADQLRGK.SFGTFDSFRRALWKAVAS-TGLVEQFT.D.NNVDRIR.EGKAPKAR...YR..DR.A..GKR....GSFELHHAD.EVA.KGG..KVYDVDNLNVVTPKHHIDIHR......................
A0A509CES8_9ENTR/109-173 ..............................................GVVT.GKGV..ELSpgT..R..WLDmsVT.NQGNGAPIPAHIADKLRGM.KFKNFDDFREALWLEVSKDPVLM----.-.-------.--------...--..--.-..---....---------.---.---..---------------------e.....................
A0A1J0VYR1_9NOCA/1712-1838 ................................gtatggedlpsvgp----.----..--G..D..Q..WLR..GS.E-GNAGWVPGQVADALRGQ.SFDSFSDFRQQFWRTVADDPDLMSQFS.R.NNQNLMA.NGNAPFAA...EG..QH.V..GGA....GRYNLHHVN.PIH.NGG..GVYDLDNLAVVTPRFHAEV--ld....................
A0A4Q5XAB7_9DELT/429-552 ..............................................GKAE.GKPA..SAA..D..E..LVF..RG.TQGSVAQVPEQLAARLRGM.TFGNFDEFRQAFWKAVSADPSLAKGFG.R.ANLARLQ.QGLAPIAP...AA..QQ.Y..GKL....KSYILHHKV.PIE.NGG..GVFDLGNIEIVSPRYHQMLH-g.....................
D3VLI3_XENNA/3-74 ........................................tyirtr----.----..---..-..-..---..--.-------------------.-HTPLDKFREDIWRAVEKDPTLKQNLKtK.ANKKAIE.KGKAPFVR...KK..DQ.V..GGR....KKLELHHIA.AI-.---..---------------------lrhf..................
A0A1V9FDB7_9BACT/54-113 ..............................................GTAA.GNGK..EIT..G..R..WLK..GS.HGNAG-LVPKSVADRLRGR.NFNNFDDFREAFGK-------------.-.-------.--------...--..--.-..---....---------.---.---..---------------------qwlkiliwqi............
A0A6C2YI70_9BACT/151-274 ...................................hggeglpgltp----.----..--G..G..V..WLD..KA.TGSVG-RVPQEVASQLRGR.SFTDWRNFRQEFWKAVGAVPELLAQFK.P.DNQARIL.AGKPPTAP...KA..GH.L..GNR....RGFELDHMD.PLD.ITGprGVYDLDNIMVAPAK-------vnlsf.................
J8VER2_PSEPU/1-80 ..............................................----.----..---..-..-..---..--.-------------------.-------MREAIWKAIGNDEMLSKQFS.R.VNISRMR.KGLAPYVP...KN..AR.V..GKR....VVMELHHKT.LIS.RGG..EVYNAENIFLTTPDLHIQIHQ......................
A0A1G8FEJ5_9VIBR/132-241 ....................................akafaaltkt----.----..---..-..-..---..--.------LIPSQIADKLRGK.EFSNFDDFRRAFWKEVSKDPTLAGQFN.L.SNIKRMK.DGKAPRAR...FK..DT.V..GGR....RSFELHHVK.EIQ.HGG..DVYNVDNIRVNTPRNHINIHK......................
A0A1G8CGI9_9VIBR/704-826 ..............................................GVVT.GNGE..DVT..G..I..WLE..EA.SKGLGSPVPSEVANKLRGK.EFSSFNEFREAFWKAISD-SELASQFS.P.SNQELMR.KGCAPFTR...FK..DQ.V..GGR....QKYEIHHKK.EIQ.HGG..GVYELDNMGITTPRNHIRIHS......................
A0A1H8EDF3_9ACTN/3580-3704 .........................................gpatg----.GYGL.aDAG..S..G..WLR..GS.Q-GNFGRIPGQVADQLRGQ.TFSSFNAFREAFWKTVGNDSDLASSFS.V.SNVTRMQ.DGGSPFTA...SG..QS.M..PGQ....FNYVLHHSM.PIW.AGG..GVYDMDNIVILTPRLHSEI--ld....................
A7MTX8_VIBC1/733-856 ..............................................GVVT.GKGE..DIF..G..I..WLA..GA.GKDLGAPIPSQIADKLRGK.EFSSFDAFRKAFWLEVSKDSDLKGQFN.A.QNQIRIG.LGKAPKAR...SR..DK.V..GKR....KSFELHHVD.EVQ.NGG..KVYDLDNLKVTTPKNHIDIHR......................
Q88NA6_PSEPK/630-754 ..............................................GTST.GHGA..QVS..D..T..WRK..EA.ASLEGAPIPAQIAELLKSR.EFRNFDAFRRQFWKAVANDPELSKQFD.E.MSLSRMRkNGYSPIVD...FP..DS.H..LSQ....KTFILHHVI.PIS.EGG..GVYDMDNIRIVTPLSHNSIHY......................
A0A2G9DCY2_9ACTN/2069-2193 ....................................gavtggyrlp----.----..VIA..G..K..WLK..GS.SGNMG-KIPGQVADVLQGR.EFQTFDDFREAFWKEVSNTPSLAKQFS.P.ANQAVMA.NGRSPRVV...SS..QR.V..GKS....DRYVLHHVT.PIQ.HGG..GVYDLDNLIVVTPQYHRDV--ld....................
A0A6M8MRR7_9PSED/108-231 ..............................................GVVS.GFGG..DID..P..Q..WET..KA.SAGLGSPIPAVVADALRGK.EYAQFRNFKRAIWREMSKHAEITQGMS.E.RNIKLIK.QGKAPIAP...NA..EQ.K..NGR....RWYEIHHIS.LIS.KGG..DVYGIDNLGINTPAQHDRIHQ......................
A0A024HC89_PSEKB/350-473 ..............................................GVVT.GEGV..EIS..G..I..WLA..DA.GVGQGAPIPSQVANKLRGK.SYRRFDDFRKDFWKAVSEVQELNGQLA.L.INQRLIR.SGNAPFVM...GS..EA.V..GRR....QKFELHHVR.RVV.DGG..EVYDVENLRVSTPRNHIFIH-a.....................
A0A7L9RTN4_9PROT/133-246 ......................................tnppvlmr----.----..---..-..-..---..-G.THNNAAKIPLEVAEKLIGK.NFKTFDSLKKAFWIEMSK-SSYARDFE.E.VNLRSMR.LGNAPDAH...PS..QW.L..GER....KSYELHHMT.PIH.DGG..AVYDMSNLLISTPKYHKEV--le....................
A0A2G1XFX9_STRCJ/1333-1457 ............................................gs--VTgGSGL.rDVD..G..K..WLR..GS.AGNAG-KIPGQIARALQGR.QFRNFDEFRQAFWTEVSKDPNLASQFT.K.SDRTLMA.DGKAPWTV...KN..QA.L..GKN....GRYVLHHVV.PIQ.RGG..GVYDLDNLIVATPRYHKEV--le....................
A0A4S4BNA4_9BACI/2-107 .......................................ynngaig----.----..---..-..-..---..--.------IIPKEIRDKLIGK.QFNSFDDFRKEFWKSVAN-SSFAKEFN.N.RNVSRML.EGNAPIAP...KV..EH.Y..GKH....KSYILHHKQ.PID.KGG..EVYNLDNLMITSPKMHQNI--ld....................
A0A5Q2K4S2_9ENTR/422-545 ..............................................GQVS.GKGQ..KVS..G..T..WLA..DA.NQGTGSPIPSQIADKLRGR.TFSNFDGFREAFWQEVSKDPELSKQFI.P.ANVTRAA.TGRAPRAR...FA..DT.V..GKR....RSFEIHHIT.PIS.QGG..EVYNVDNMGVMTPKRHIDTH-s.....................
A0A077LDN9_9PSED/1-110 .............................................m----.----..---..-..-..--G..ET.TRGRGVPIPEHIADQLRGR.NFSSFRKFREALWAAIANDPDLQKQFT.G.QNKLEMS.QGRAPYAR...AE..DQ.A..GDN....KKFEVHHPH.EIA.HGG..AVYDIDNMLIMTPRRHIEHHQ......................
W1DQY5_KLEPN/196-281 ..............................................GTVS.GKGQ..NVG..N..N..WMG..GA.STGDGAPVPSQIADKLRGK.TFGSFDSSRRAFWKAVADDSALSKQFS.E.ADINQMK.AGRAPTAD...F-..--.-..---....---------.---.---..---------------------frisr.................
A0A2K9PSG6_9FLAO/6-127 ..............................dnskikktkvqnsnsi----.----..---..-..-..---..--.-SKKSIAIPQEVQNYIHNNvNSSNYNYVRRIINKQWANHPEARKCFN.E.DSLKEMR.KGRNPYAP...IN..ER.L..GRR....VKMEYDHYR.EQQvEGT..DSCDVSNLRLVSPYIHAK---ki....................
A0A1Y4SVF6_9FIRM/257-379 ..............................................GTVT.GADK..LPN..V..Q..TMM..RG.THGNIGVIPKEVGEKLQGK.TFNDFDEFRHAFWTEIGN-SKYANEFS.A.SNRSLMQ.AGKAPFTA...LE..QT.N..GQH....SKYVIHHLT.PIH.VGG..NVYDLSNMIISTPRMHVDI--ld....................
Q87UR4_PSESM/526-649 ..............................................GVAS.GYGE..PVT..G..V..WLG..DR.TRAEGASIPTHIADQLRGR.RFGDFASLRKATWIAVADDPELGKQST.Q.NNLEIMR.GGGAPHPK...LS..DQ.A..GGR....TRFEIHHKN.YIS.KGG..AVYDIDNLVIMTSRQHIDHHR......................
A9MMY5_SALAR/1063-1194 ..............................................GTAT.GNGV..KLS..G..DkpWLDlsVT.NKGNGAPIPSHIADKLRGR.SYGSFDDLREDLWEEISNDPKLMAQFG.E.DNQERIS.NGLAPWVP...SD..GY.Y.hGPNe.vvKKFQIHHDQ.AIE.DGG..GVYDLDNLRIVTPRLHDEIHY......................
A0A3N4B9L8_YERPE/1-78 .............................................m----.----..---..-..-..---..--.-------------------.----------TFWREVANEPELVGQFK.P.NNVSLMK.KGLSPHPV...LS..EK.V..GGR....DTFEIHHVN.SIK.SGG..AVYDVDNLRVATPKRHIEIHS......................
A0A3M0M9V3_9RHOB/337-461 ..............................................GIAT.GTGV..RID..G..D..WLR..ESiRTGTGAPIPDRIAAKLAGR.DFNTFDDFRESFWQEVAADAELAVQFD.EiKNLPRLR.AGKPPIAP...RH..EH.Q..GKT....VWFELDHIE.PLF.KGG..PVYDMDNLQVLTPRAHTR---ks....................
A0A3S5D9R2_SALBN/1-112 .............................................m----.----..---..-..-..---..-T.NNGNGAPIPAHIADKLCGR.EFKNFDNFREALWLEVSKDPVLMEQFS.E.FNQIRIS.HGFTPFVP...DK..GH.Y.vGPKe.ivKKFQIHHFI.SIE.YGG..GVYNIDNLRIVTPKLHDEIHY......................
A0A1G9NN07_9PSED/145-268 ..............................................GVVT.GQGE..VVT..G..I..WLE..QA.SRELGAPIPAQIADRLRGK.AFASFDAFRAEFWRAVADDFELSSQFS.N.VNRRRMR.GGSSPFVI...PE..EA.V..GGR....ISFELHHVD.PVA.QGG..PVYDLDNLRVNTPRNHIELHQ......................
A0A1H3M140_9BACL/304-425 ..............................................GIAT.GQNL..KEV..D..K..MMR..GT.EGNVG-IIGKDVGDQLIGK.NYKNFDEFRQDFWKSVANS-KHRDEFG.A.SNVSRME.KGFAPIVT...KS..QV.H..GKI....KSYVLHHRT.PIH.AGG..EVYDLDNLLVVTPKMHQEI--ld....................
A0A554VBD5_9FLAO/761-882 ..............................................GVVK.GKGV..KIN..G..K..WLK..GT.HGNAG-FFPEAIAKKMKGK.TFNNFDEFREAFWKNVSDDPRLADQFS.D.SNKALMK.KGKAPKVS...NT..QN.L..GGQ....NTYQLHHKK.PIN.QGG..GVYDMDNLFIVTPRYHKEI--l.....................
A0A5R9QBD0_9GAMM/309-432 ..............................................GVVT.GIGE..TIG..D..K..WLE..NA.GVGRGAPVPSQIAEVLRGK.SFSSFDQFRRAFWLAVSQDADLSGRFN.G.GNKARMA.QGLAPRAR...FA..ET.I..GER....RSFELHHET.PVA.QQG..EIYNVDNIRAMTPKHHIDTHR......................
A0A3E0H1T5_9PSEU/1157-1281 ..............................................GRAT.GAGDlpDVN..G..K..WLR..GS.HG-NAGRIPGQIARQLQGQ.QFNTFDDFRKAFWKAVGNDPQLSSQFS.P.SNVRRMQ.NENAPIAH...SS..QH.V..GKV....KSYALHHVT.PIQ.HGG..AVYDMRNIVVVTPQFHRDV--ld....................
A0A3R8VNI6_9PSED/214-318 ..............................................GAAS.GEGQ..DVL..T..G..WLG..L-.TEGEGAPIPKQIADQLRGR.TFSSFSQFRGVFWKLVAADEMLVPQFS.I.LNLDRMR.RGYSPVVT...ED..QR.V..GRR....EVLEIHHIN.HIS.KGG..G--------------------gl....................
A0A8J7GUC1_9ENTR/163-288 ..............................................GVVT.GKGE..VLS..GggK..WLE..AA.SAGLGAPVPAQVADKLRGQ.KFERFDDFREAFWLAVAECPELMEQFS.P.ANKALIK.KGRSPYAV...PK..EQ.S..GGR....TVFEIHHKI.RIV.DGG..SVYDIENMSIATPKRHIMLH-s.....................
K6TUC4_9CLOT/2394-2509 ..........................gittqnnkidvnqnklmyqs----.----..---..-..-..---..--.-GNI-GVIPQEIKDRLNNR.TFNNFKELRSALWEEVGN-SKYATEFG.K.SGQTLMK.NGMAPYSN...S-..--.-..---....GKYVIHHKQ.PIA.KGG..GVYDLDNLIILSPKMHKI---iid...................
I4MVQ3_9PSED/114-237 ..............................................GIAT.GRGE..DVF..G..I..WLA..GA.GTGLGAPIPTRIANVLRGR.EFKSFDTFRAAFWKAVSNDPELFSQLS.E.DDQARVL.TGNAPTVR...FR..DS.V..GKR....VTYEIHHIE.LIK.DGG..AVYDADNLRVNTPRNHIDLHK......................
A0A1B7K407_9GAMM/481-604 ..............................................GTAT.GNGK..KVG..D..K..WLN..DA.GKENGVPIPEQVANKLRGK.KFKTCDDFRKKFWEAVSKDPVLRKQFI.K.GNQNRMS.KGLAPRAR...NK..GT.V..GGR....RSFEIHHDT.PIS.EGG..EVYNIDNLRIVTPKRHIDIHR......................
A0A1G7HEI6_9FLAO/89-184 ......................................pfglecwg----.----..---..-..-..---..--.-------------------.------TARKKFWKNEAA--NNSGGYS.P.NNLKRMK.EGKAPKMT...VEvtNRkT..GVTttrdYSMELHHKD.IPQ.RVGgdGVHDSSNLDALTPWEHEA---vde...................
A0A1Y6INM4_9VIBR/424-547 ..............................................GVVT.GTGE..DIT..G..Q..WLE..AA.GKELGSPVPSQIADKLRGR.EFSSFDEFREAFWLTVSEDKSLMSQFS.R.SNQTLIR.MGNAPYSV...PE..DQ.A..GGR....KTYEIHHVE.EIQ.HGG..AVYDVDNMRVNTPKNHINIHR......................
A0A1R3UQW6_9ACTN/550-674 ..............................................GTAT.GGQNlpQVT..G..T..WLR..GT.EGNAG-RTPRQIADQLEGR.SFDTFDQFRGAYWNAVADTPELAGQFA.P.HQVTRMR.NGNAPFAV...QN..QQ.V..GGQ....RSYVLHHIT.PIG.RGG..GVYDLDNIMVVTPRYHRDI--ld....................
A0A0A5HUK2_9BACI/3-76 ...........................................igk----.----..---..-..-..---..--.-------------------.--------------SVAN-SSFAEEFN.S.RNVTRML.E-DAPIAP...KL..EH.Y..GKH....KSYILHHKQ.PID.KGG..EVYNLDSLIITSPKMHQNI--ld....................
I4N884_9PSED/1-111 .............................................m----.----..---..-..-..WLA..DA.DSGIGAPIPAELADALRGQ.SFNGFDTFRSAFWKAVST-SRFADQFA.P.QNTGRMQ.TGRAPRAR...KA..DR.V..GGR....LSYELHHVR.KVS.EDG..GVYDIDNLRVNTPKNHIDLHR......................
PYS2_PSEAE/563-686 ..............................................GAAT.GKGQ..PVS..G..N..WLG..AA.SQGEGAPIPSQIADKLRGK.TFKNWRDFREQFWIAVANDPELSKQFN.P.GSLAVMR.DGGAPYVR...ES..EQ.A..GGR....IKIEIHHKV.RIA.DGG..GVYNMGNLVAVTPKRHIEIHK......................
A0A315WYZ4_9PSED/269-392 ..............................................GVVT.GIGQ..DVI..G..I..WLA..GA.SAGLGAPIPTRIADRLRGR.EFSNFDALRKAFWVEVGNDPELLSQFV.Q.RNVKRMQ.NGYAPNAR...DK..DT.V..GKR....NTFELHHIE.RIV.DGG..AVYDVDNLRVNTPKNHINLHR......................
A0A3S4E8E7_SALBN/1-79 ............................................ms----.----..---..-..-..---..VT.NQGDGAPIPAHIADKLRGR.EFKIFDDFREALWLEVSKDPVLMEQFI.K.SNLMPL-.--------...--..--.-..---....---------.---.---..---------------------dedvllshlqkatimvqmksli
A0A2S1LQ14_9FLAO/84-179 ......................................aksyaqkk----.----..---..-..-..---..--.-------------------.---AWKDAREAYWKKEAK--KNKKDYS.Q.HNLDRMK.KGTAPQLQvevEN..NK.T..GRKetkvVSMELHHKK.AQH.LGG..-SNKSSNLQKVTPWEHEAI--dt....................
A8AJ94_CITK8/451-576 ..............................................GTAT.GYGEilPEN..S..R..WLE..AA.SSGLGAPIPAQVADKLRGR.TFRNFDHFREEFWLAVSECPELMKDFK.P.SNQTLIR.MGLAPYPI...PS..EQ.V..GGR....TTFELHHLE.EIQ.HGG..EVFNMDNINITTPRLHTGIHK......................
A0A8H9IMQ9_9PSEU/1348-1472 ......................................gtahgsag----.---I.pDVD..G..Q..WRR..G-.SQRNAARFPGQVARQLEGR.HFNNFDEFREAFWREVHADPNLRSQFP.P.GSQGNMA.NGHSPFVV...DE..QT.F..GGR....SRYELHHVT.PIQ.HGG..GVYDMRNIVIVTPRYHRDI--ld....................
A0A7K4ELU5_9PSED/601-724 ..............................................GVAT.GNGQ..SVS..G..L..WLG..TA.DTREGSPIPSRIADQLRGL.TFSNWDRMREAIWKAVAADTELSQQFI.P.SNLQRMR.EGGAPKSA...AS..GH.N..KSK....KSFELHHVH.QIA.KGG..AVYDIDNIVVMTPKQHAEIHS......................
A0A5J5G413_9GAMM/14-123 ngnaagdgpsgptaarslssraltpldttnpvrkrssmkqdtvlka----.----..---..-..-..---..--.-------------------.----------------------VSTIA.G.QDQISLK.AGSAPYPI...LP..DQ.I..LQ-....KTVELHPVD.NIQ.HEG..PVYGIDNPNANTHSHHISRH-m.....................
A0A066UC02_9GAMM/8-117 ........................................eslfkg----.----..---..-..-..---..--.--GNSAPVPKQVADKLSGR.SFSNFDEFRSAFWKEMANDPAVAQNFN.P.QNLALMR.RGNAPIAP...KS..QY.N..GNN....KRYELDHNI.EIR.DGG..TIYNLDNIIIRTPKDHAD---kts...................
A0A7X6EJT3_9PSED/291-414 ..............................................GTVT.GIGE..DVS..G..I..WLA..GA.GTGIGVPIPTRIADRLRGR.EFSSFDKFREAFWEEVANDPELVEQFK.P.ENIALMQ.NGGAPHAR...YN..DA.A..GKR....KTFELHHVE.WVS.KGG..SVYDVDNLRVTTPANHLNIHR......................
A0A1W2FUC7_9PSEU/1-86 .............................................m----.----..---..-..-..---..--.---------------LEGR.SFDSFDDFRKVFWMAVAADAYLVSQFD.R.RDKYRLA.AGYAPAED...ES..QR.H..GGQ....SRYVLHHIQ.PIQ.HEG..GVYDLNNIIVAPP--------ev....................
Q13MM2_PARXL/1-67 ..............................................----.----..---..-..-..---..--.---------------MRGQ.KFRDFDHFRSGFWKAVPKDTDLISQFS.K.LNVSRMS.DGLAPKSF...SD..AR.C..RKK....---------.---.---..---------------------hvlrfasyrans..........
A0A8J7FVE1_9CYAN/641-767 ..............................................GTAT.GGETlpDVT..G..R..WFQ..DE.-QGRLARVPGQIARDMQGM.HFDNFGQFREAFWRRVAADPNLSAGWR.P.DDLKNMR.QGRAPGAP...SA..ER.TggGGN....AVYQLDHLT.PIE.LGG..GVYDLDNIQVVAPRTHVEL--gr....................
A0A285NN04_9PSED/555-675 ............................................hi---E.GVGK..AAG..A..D..FLL..RA.SQPEGVAIPSAIADPLRGR.AYATPAAVERAIWRTLGDIPELAQAFE.P.PNRARLA.LGLAPYAP...RA..TW.M..GGR....HHFELRIAQ.PST.AG-..-SFDLDHLRMAAPSS------ewgarh................
A0A1G5KM92_9HYPH/652-768 ..........................nevkkkldknildqdvlnll----.----..---..-..-..---..--.--------PHALRKEIKGI.VKKRWDDIRKAFWKSVRSDNALVKELK.E.LGIR-FE.GTSAGSAP...DL..TL.A..GVK....MKCSLDHVKrKVE.NPL..EAFSADNLRILTGRD------nsvlk.................
A0A5Q0JT95_9FLAO/1595-1717 ..............................................GTAA.GNGK..NIS..G..T..WLR..GT.EGNAG-LFPQSIANQLKNQ.QFSTFDKFREAFWKAVANDSHLASQFS.S.SNLTRMQ.NGFAPFVK...QS..QQ.L..GGQ....TKYILHHKT.PIN.QGG..AVYNMDNLYIVTPKYHKEI--ld....................
Q7N5Q1_PHOLL/433-556 ..............................................GVVT.GQGQ..RVE..G..N..WLS..LA.GQDMGAPIPSQIADKLRGR.RFNNFDDFRRAFWKEVGNDPELSQQFN.S.HNKEFLK.KSYSPYSP...RQ..EH.I..GNR....EKYEIHHVK.FIK.DGG..EVYNLDNLRVTTPKRHIEIHS......................
A0A177QTE1_9BACT/2-117 ...........................................npg----.----..---..D..T..WFR..G-.THANAAKVPGQIAEKLRGQ.QFRSWDHFRESFWKEVANDPVLSKNFK.I.DDVLLMKnKGTAPRAS...ET..QW.E..NSI....RGYQIHHKN.PIH.NGG..NVYDMDNLLIVTPRYHREI--ls....................
L0M703_ENTBF/460-585 ..............................................GVAT.GNGQ..VIP..D..NvrWLE..AA.SSGIGAPIPAQVADKLRGR.EFRDFNHFRKELWRAVSECPELLSQLK.A.SNQSIVK.IKGSPYVI...PE..QA.V..GGR....EVFELHHLK.QIQ.HDG..PVYDMDNLRVNTPLNHIRIHK......................
A0A553ATJ3_9RHOB/44-167 ..............................................GVAS.GAGQ..QVG..A..D..WLN..AG.IRTGAMPIPASVAERLEGR.RFGSFDAYRRAFWKAVAQEPELMGQFD.R.RSQEAIK.KGFAPSTP...KS..VR.V..GKR....DRWELDHIN.PLW.NNG..ELYGADNLQIMPPKSHIEK--tr....................
A0A1H4G7H6_9GAMM/82-207 ..............................................GIVT.GQGE..VLT..G..EgkWLD..AA.SSGLGAPIPAQVADKLRGR.EFKTFDAFREAFWLAVSECPELLEQFK.R.SNQVLIQ.AGNAPYPI...PL..EQ.V..GGR....KTFELHHVK.NIQ.HDG..PVYDVDNLRVNTPRNHINIHK......................
A0A1Y6ISU1_9VIBR/304-427 ..............................................GVVT.GNGE..DVT..G..L..WLE..AA.GKELGSPVPSQIADNLRGR.EFSSFDSFRKAFWLAISEDENLMSQFN.R.NNQKKIR.AGKAPFAP...QD..QK.Y..GET....MRFEIHHIE.EIQ.HGG..AVYDVDNMRVVTPKNHKRIHY......................
A0A1G9FKP4_9PSED/323-446 ..............................................GVVT.GRGE..VVT..G..I..WLE..QA.SRELGAPIPAQIADKLRGK.AFSSFDAFRKAFWTEVGNDAELSSQFG.R.LNQANMK.NGFAPFPI...PA..EQ.V..GGR....KVFELHHVE.PIA.QGG..AVYDMDNLRIITPKRHIELH-s.....................
A0A0D8ZMX4_9CYAN/2-104 ............................................gl----.----..---..-..-..---..--.-------IPGQIARRMQGM.YFNNFGEFRKTFWKLVEQDPYLRKGWT.K.GNIKRMR.QGMAPIAP...RA..EQ.TggGAN....KVYQLDHSH.DLQ.HGG..EVYDLGNIRIVSPRFHQQ---ygr...................
A0A663BLV5_9ENTR/163-286 ..............................................GTVS.GKGQ..NVG..N..N..WMG..GA.STGDGAPVPSQIADKLRGK.TFGSFDSFRRAFWKAVADDSALSKQFS.E.ADINQMK.AGRAPTAD...FL..ES.V..GKR....VKIELHHEK.EIS.QGG..AVMDVDNIKALTPKNHIETHK......................
A0A7L4XUF0_9ACTN/1388-1512 ..............................................GAVT.GGSRlkDVS..G..K..WLL..GT.HGNVG-KIPGQVARGLQGR.QFNSFDKFREAFWLEVAKHPKLVNQFI.P.GNRALIK.QGKAPRTV...PR..QA.I..GKN....NYYSLHHVN.PIH.NGG..GVYDLDNIIVVTPRYHREV--ld....................
A0A7K4EKR1_9PSED/358-479 ..............................................GVVS.GGGQ..VAA..P..G..WWD..AS.ARTSGAAIPAQAADTLRGR.EFASFAGFEQALWRSIGEEAAPGGTFS.E.INQRRIA.NGLAPYAP...KS..TW.L..GER....REFEVRYSQ.SAA.LGN..APYDLDRLSLHSPA-------safgv.................
#=GC seq_cons ..............................................G.sp.G.s....hs..s.....Wht..ts.sts.GuslPsplA-pLRG+.pFssFDpFRcAFWctVupDspLspQFs.t.sNhpphp.pGtAPhs....tp..pp.h..Gt+....ppaELHHhp..Ip.pGG..sVYDlDNlhlsTP+.Hhpl........................
//
