#=GF ID Colicin-DNase
#=GF AC PF12639.11
#=GF DE DNase/tRNase domain of colicin-like bacteriocin
#=GF PI Colicin-DNAse;
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE pdb_1bxi
#=GF GA 25.00 25.00;
#=GF TC 25.00 25.10;
#=GF NC 24.90 24.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF CL CL0263
#=GF RN [1]
#=GF RM 10368275
#=GF RT The crystal structure of the DNase domain of colicin E7 in
#=GF RT complex with its inhibitor Im7 protein.
#=GF RA Ko TP, Liao CC, Ku WY, Chak KF, Yuan HS;
#=GF RL Structure. 1999;7:91-102.
#=GF RN [2]
#=GF RM 11741540
#=GF RT Crystal structure of colicin E3: implications for cell entry and
#=GF RT ribosome inactivation.
#=GF RA Soelaiman S, Jakes K, Wu N, Li C, Shoham M;
#=GF RL Mol Cell. 2001;8:1053-1062.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Colicin-like bacteriocins are complex structures with an
#=GF CC N-terminal beta-barrel translocation domain (Pfam:PF09000), a
#=GF CC long double-alpha-helical receptor-binding domain (Pfam:PF11570)
#=GF CC and this C-terminal RNAse/DNase domain with endonuclease
#=GF CC activity. Their competitor bacteriocidal action is by a process
#=GF CC that involves binding to a surface receptor, entering the cell,
#=GF CC and, finally, killing it. The lethal action of colicin E3 is a
#=GF CC specific cleavage in the ribosomal decoding A site. The crystal
#=GF CC structure of colicin E3 reveals a Y-shaped molecule with the
#=GF CC receptor binding domain forming a 100 Angstrom long stalk and
#=GF CC the two globular heads of the translocation domain and this
#=GF CC catalytic domain comprising the two arms [2].
#=GF SQ 206
#=GS A0A1H9WL48_9CORY/221-313 AC A0A1H9WL48.1
#=GS A0A521DMS3_9BACL/365-461 AC A0A521DMS3.1
#=GS A0A1C0Y6X3_9BACL/188-284 AC A0A1C0Y6X3.1
#=GS A0A2W1LEH5_9BACL/40-156 AC A0A2W1LEH5.1
#=GS A0A1X9SRT5_9PROT/86-182 AC A0A1X9SRT5.1
#=GS A0A6I1E8L0_9RHOB/9-81 AC A0A6I1E8L0.1
#=GS Q813C3_BACCR/128-202 AC Q813C3.1
#=GS A0A2T4VRF7_VITXG/417-491 AC A0A2T4VRF7.1
#=GS T0P7W1_PHOTE/47-122 AC T0P7W1.1
#=GS M4R7C3_BIBTR/94-200 AC M4R7C3.1
#=GS A0A495X6A4_9PSEU/2890-2965 AC A0A495X6A4.1
#=GS A0A084H239_METID/108-215 AC A0A084H239.1
#=GS A0A517SU77_9BACT/415-492 AC A0A517SU77.1
#=GS A0A6I0FXI3_9CORY/1150-1237 AC A0A6I0FXI3.1
#=GS A0A024QDV7_9BACI/75-164 AC A0A024QDV7.1
#=GS A0A1Y5JXX5_9BACL/223-317 AC A0A1Y5JXX5.1
#=GS A0A1H8K7F0_9BACI/183-279 AC A0A1H8K7F0.1
#=GS A0A2N5GYX6_9BACI/190-287 AC A0A2N5GYX6.1
#=GS A0A433RSC7_9BACL/162-259 AC A0A433RSC7.1
#=GS A0A562NU75_9RHOB/110-212 AC A0A562NU75.1
#=GS A0A151AUQ6_9CLOT/76-172 AC A0A151AUQ6.1
#=GS F0EWF2_9NEIS/1-79 AC F0EWF2.1
#=GS Q21ED9_SACD2/494-574 AC Q21ED9.1
#=GS A0A3N6A8T6_9BACL/291-380 AC A0A3N6A8T6.1
#=GS V2YCR9_9FIRM/86-209 AC V2YCR9.1
#=GS A0A7D3XKM2_9BACL/357-468 AC A0A7D3XKM2.1
#=GS A0A5D0CL15_9BACL/982-1077 AC A0A5D0CL15.1
#=GS A0A7W2AJ92_9BACL/262-332 AC A0A7W2AJ92.1
#=GS A0A3D8GW38_9BACI/97-189 AC A0A3D8GW38.1
#=GS A0A512IN46_9HYPH/213-315 AC A0A512IN46.1
#=GS A0A1E3X7A1_9BACT/91-189 AC A0A1E3X7A1.1
#=GS S9QKF2_9DELT/461-561 AC S9QKF2.1
#=GS A0A3N1CT66_9ACTN/279-354 AC A0A3N1CT66.1
#=GS A0A7C9F201_9BACT/272-364 AC A0A7C9F201.1
#=GS A0A1H9MKM1_9BACI/187-285 AC A0A1H9MKM1.1
#=GS A0A0G2ZRS4_9DELT/384-484 AC A0A0G2ZRS4.1
#=GS A0A7W1XPV6_9BACL/117-238 AC A0A7W1XPV6.1
#=GS A0A7X9QT84_9BACI/137-236 AC A0A7X9QT84.1
#=GS A6CCT8_9PLAN/320-434 AC A6CCT8.1
#=GS A0A090KNQ6_9BACI/1-83 AC A0A090KNQ6.1
#=GS S9PAR3_9DELT/371-471 AC S9PAR3.1
#=GS J4K7K3_9FIRM/60-157 AC J4K7K3.1
#=GS A0A1V3J3X8_9PAST/48-152 AC A0A1V3J3X8.1
#=GS A0A841TB29_9BACL/216-311 AC A0A841TB29.1
#=GS A0A2N5MC83_9BACI/188-286 AC A0A2N5MC83.1
#=GS Q813C4_BACCR/110-217 AC Q813C4.1
#=GS A0A1H9VI96_9BACI/191-289 AC A0A1H9VI96.1
#=GS R7IVH5_9CLOT/145-242 AC R7IVH5.1
#=GS A0A410DYL3_9CLOT/2036-2152 AC A0A410DYL3.1
#=GS A0A2D1SSY2_9BACL/231-339 AC A0A2D1SSY2.1
#=GS A0A0M0LBD2_9BACI/79-175 AC A0A0M0LBD2.1
#=GS A0A1G6A216_EUBOX/31-108 AC A0A1G6A216.1
#=GS A0A7W2AJ39_9BACL/357-449 AC A0A7W2AJ39.1
#=GS A0A7W2AJ92_9BACL/340-426 AC A0A7W2AJ92.1
#=GS A0A4Z0GRQ6_9BACL/454-545 AC A0A4Z0GRQ6.1
#=GS A0A1S2LPC6_9BACI/226-322 AC A0A1S2LPC6.1
#=GS A0A3A9A4H5_9BACT/119-212 AC A0A3A9A4H5.1
#=GS A0A4P8XH22_9BACL/1-48 AC A0A4P8XH22.1
#=GS F5LP02_9BACL/851-939 AC F5LP02.1
#=GS A0A099W418_9LIST/393-483 AC A0A099W418.1
#=GS Q97IJ5_CLOAB/194-301 AC Q97IJ5.1
#=GS Q9X367_BACAN/304-399 AC Q9X367.1
#=GS A0A0H3KRT6_BURM1/1416-1516 AC A0A0H3KRT6.1
#=GS A0A0B0HGQ8_9BACL/106-201 AC A0A0B0HGQ8.1
#=GS A0A0G2ZYM2_9DELT/271-371 AC A0A0G2ZYM2.1
#=GS A0A235B634_9BACL/24-113 AC A0A235B634.1
#=GS H1FWZ5_SULGG/241-338 AC H1FWZ5.1
#=GS A0A5C8M297_9BACL/111-208 AC A0A5C8M297.1
#=GS A0A090IV55_9BACI/46-134 AC A0A090IV55.1
#=GS A0A3A9CYR2_9BACT/73-166 AC A0A3A9CYR2.1
#=GS A0A1M6N0W0_9CLOT/132-227 AC A0A1M6N0W0.1
#=GS A0A1L3MX79_9BACI/37-135 AC A0A1L3MX79.1
#=GS A0A4U1JIE8_9DELT/481-559 AC A0A4U1JIE8.1
#=GS A0A0A2TFF8_9BACI/184-282 AC A0A0A2TFF8.1
#=GS A0A1Q9PW75_9BACI/188-286 AC A0A1Q9PW75.1
#=GS R6A7W5_9FIRM/269-369 AC R6A7W5.1
#=GS A0A1R1E663_9BACL/92-187 AC A0A1R1E663.1
#=GS A0A165VU93_9HYPH/23-137 AC A0A165VU93.1
#=GS A0A523Q329_9BURK/106-203 AC A0A523Q329.1
#=GS A0A0H4KM13_9BACI/94-193 AC A0A0H4KM13.1
#=GS A0A1Y3U5N7_9ACTN/263-363 AC A0A1Y3U5N7.1
#=GS A0A2U2AD11_9GAMM/78-173 AC A0A2U2AD11.1
#=GS A0A1R3T9A7_9BACT/2475-2568 AC A0A1R3T9A7.1
#=GS A0A3L7Z318_9BACE/113-221 AC A0A3L7Z318.1
#=GS A0A075JZU8_9BACI/595-684 AC A0A075JZU8.1
#=GS A0A073JXS7_9BACI/441-536 AC A0A073JXS7.1
#=GS A0A1M4Y7Q8_9BACL/336-446 AC A0A1M4Y7Q8.1
#=GS Q6NG78_CORDI/1149-1243 AC Q6NG78.1
#=GS A0A521CYH4_9BACL/376-471 AC A0A521CYH4.1
#=GS A0A4S4BSR3_9BACL/146-239 AC A0A4S4BSR3.1
#=GS R5NNX8_9CLOT/142-237 AC R5NNX8.1
#=GS A0A346NSH6_9ALTE/1-87 AC A0A346NSH6.1
#=GS A0A1I0MWL6_9FIRM/424-521 AC A0A1I0MWL6.1
#=GS A0A7W1XRW3_9BACL/7-86 AC A0A7W1XRW3.1
#=GS A0A248TG41_9BACI/265-354 AC A0A248TG41.1
#=GS N2A0U7_9FIRM/1-92 AC N2A0U7.1
#=GS D5SL35_STRCL/2233-2308 AC D5SL35.1
#=GS A0A2N7DFW9_9VIBR/143-235 AC A0A2N7DFW9.1
#=GS A0A165VUG1_9HYPH/118-223 AC A0A165VUG1.1
#=GS A0A4V6WQK2_9DELT/482-560 AC A0A4V6WQK2.1
#=GS A0A0V8JPB4_9BACI/175-270 AC A0A0V8JPB4.1
#=GS A0A2P7QW45_9SPHN/4471-4560 AC A0A2P7QW45.1
#=GS A0A0G2ZTA3_9DELT/436-536 AC A0A0G2ZTA3.1
#=GS A0A7W5CC75_9BACL/76-173 AC A0A7W5CC75.1
#=GS A0A3N5C744_9BACI/105-207 AC A0A3N5C744.1
#=GS A0A844Q9G6_9BACL/79-175 AC A0A844Q9G6.1
#=GS A0A5J5FY52_9GAMM/1294-1391 AC A0A5J5FY52.1
#=GS M4RA36_BIBTR/360-458 AC M4RA36.1
#=GS A0A1Y6BQN1_9PROT/232-318 AC A0A1Y6BQN1.1
#=GS A0A1E5KTS4_9ENTE/428-523 AC A0A1E5KTS4.1
#=GS A0A448TS41_9PAST/78-189 AC A0A448TS41.1
#=GS A0A2T4V330_VITXG/211-309 AC A0A2T4V330.1
#=GS A0A317DML2_9ACTN/2935-3012 AC A0A317DML2.1
#=GS A0A060LSR5_9BACI/2-84 AC A0A060LSR5.1
#=GS A0A0F5RCW0_9BACL/66-173 AC A0A0F5RCW0.1
#=GS A0A4R3L271_9BACL/377-490 AC A0A4R3L271.1
#=GS A0A1W2CSP5_9FIRM/111-185 AC A0A1W2CSP5.1
#=GS A0A521FHP5_9BACL/217-314 AC A0A521FHP5.1
#=GS A0A1N7LCD4_9BACL/523-575 AC A0A1N7LCD4.1
#=GS A0A7D3Y4X3_9BACL/388-502 AC A0A7D3Y4X3.1
#=GS A0A1H2R9W0_9FIRM/110-215 AC A0A1H2R9W0.1
#=GS A0A7X9M0R1_9BACI/133-231 AC A0A7X9M0R1.1
#=GS A0A0L6JKS8_9FIRM/142-233 AC A0A0L6JKS8.1
#=GS A0A0C2B265_9ACTN/447-522 AC A0A0C2B265.1
#=GS A0A3S0P272_9BACI/184-281 AC A0A3S0P272.1
#=GS A0A1Y0I1B0_9GAMM/1189-1291 AC A0A1Y0I1B0.1
#=GS A0A2T6FQR1_9GAMM/1-90 AC A0A2T6FQR1.1
#=GS R5CZP8_9FIRM/107-180 AC R5CZP8.1
#=GS W4Q7V4_9BACI/226-322 AC W4Q7V4.1
#=GS A0A0C5VDM0_9GAMM/1647-1757 AC A0A0C5VDM0.1
#=GS A0A2S1H3I0_9BACI/188-284 AC A0A2S1H3I0.1
#=GS A0A235B608_9BACL/408-506 AC A0A235B608.1
#=GS A0A7W2AQW9_9BACL/515-607 AC A0A7W2AQW9.1
#=GS A0A3A1R1X8_9BACI/1-83 AC A0A3A1R1X8.1
#=GS A0A150L154_9BACI/216-305 AC A0A150L154.1
#=GS A0A7X2L543_9BACL/603-692 AC A0A7X2L543.1
#=GS A0A074LWM1_9BACL/420-518 AC A0A074LWM1.1
#=GS A0A7H0SLJ7_9CORY/1154-1239 AC A0A7H0SLJ7.1
#=GS A0A2B4R3Q3_STYPI/377-476 AC A0A2B4R3Q3.1
#=GS A0A7W1XR52_9BACL/302-364 AC A0A7W1XR52.1
#=GS A0A6I6EJX1_9GAMM/298-391 AC A0A6I6EJX1.1
#=GS A0A4U1IWB1_9DELT/437-512 AC A0A4U1IWB1.1
#=GS A0A1V4SDV0_RUMHU/351-447 AC A0A1V4SDV0.1
#=GS Q3IK23_PSET1/94-190 AC Q3IK23.1
#=GS A0A3M0M802_9RHOB/568-670 AC A0A3M0M802.1
#=GS A0A553ZVQ8_9BACI/199-296 AC A0A553ZVQ8.1
#=GS A0A3Q8S6W2_9BACL/5-92 AC A0A3Q8S6W2.1
#=GS A0A2N0Z0C7_9BACI/188-286 AC A0A2N0Z0C7.1
#=GS A0A1V4H651_9BACL/853-948 AC A0A1V4H651.1
#=GS W0JAX2_9BACT/1951-2042 AC W0JAX2.1
#=GS A0A7W1XRL6_9BACL/1-64 AC A0A7W1XRL6.1
#=GS E5C6Z5_9BACE/57-145 AC E5C6Z5.1
#=GS A0A1H0N555_9BACL/218-314 AC A0A1H0N555.1
#=GS A0A1Y0KZ04_9PSED/154-253 AC A0A1Y0KZ04.1
#=GS A0A6B3W5L7_9BACI/47-142 AC A0A6B3W5L7.1
#=GS A0A3M8P3L6_9BACL/189-286 AC A0A3M8P3L6.1
#=GS A0A2N0Z977_9BACI/188-286 AC A0A2N0Z977.1
#=GS D5DUB0_PRIM1/5-60 AC D5DUB0.1
#=GS R9J028_9FIRM/240-328 AC R9J028.1
#=GS A0A081N1C2_9GAMM/1-52 AC A0A081N1C2.1
#=GS A0A259U9V6_9FIRM/27-102 AC A0A259U9V6.1
#=GS A0A263BSU2_9BACI/189-286 AC A0A263BSU2.1
#=GS A0A4Q5NK23_9BACT/107-201 AC A0A4Q5NK23.1
#=GS R6NAU6_9FIRM/1-72 AC R6NAU6.1
#=GS A0A1Y0IPX4_9BACL/161-256 AC A0A1Y0IPX4.1
#=GS A0A1I6K0A3_9FIRM/1-87 AC A0A1I6K0A3.1
#=GS A0A4Y9J2Z9_9LACT/22-117 AC A0A4Y9J2Z9.1
#=GS W4VPR9_9BACI/162-251 AC W4VPR9.1
#=GS A0A1H9UFE7_9BACI/87-183 AC A0A1H9UFE7.1
#=GS A0A7W1XQR4_9BACL/2-67 AC A0A7W1XQR4.1
#=GS M5DV04_9GAMM/115-211 AC M5DV04.1
#=GS A0A1V3IQD5_9PAST/1-66 AC A0A1V3IQD5.1
#=GS A0A0Q4R3I9_9BACL/76-164 AC A0A0Q4R3I9.1
#=GS A0A1H3M3G2_9BACL/523-609 AC A0A1H3M3G2.1
#=GS A0A2I7SVY8_LACSH/338-457 AC A0A2I7SVY8.1
#=GS A0A7X6S2T2_9LACO/185-267 AC A0A7X6S2T2.1
#=GS A9AVI8_HERA2/2989-3061 AC A9AVI8.1
#=GS E6TT53_EVAC2/222-318 AC E6TT53.1
#=GS A0A0B2BZY0_9SPHN/431-535 AC A0A0B2BZY0.1
#=GS A0A843YFI3_9RHOB/187-273 AC A0A843YFI3.1
#=GS A0A1I6ZFC0_9FIRM/148-247 AC A0A1I6ZFC0.1
#=GS A0A1I6CC54_9BACI/186-283 AC A0A1I6CC54.1
#=GS A0A2W7PD22_9BACI/190-286 AC A0A2W7PD22.1
#=GS A0A150KN56_9BACI/509-608 AC A0A150KN56.1
#=GS A0A1M4ZVR7_9BACL/323-396 AC A0A1M4ZVR7.1
#=GS A0A4P6UUS2_9BACL/121-219 AC A0A4P6UUS2.1
#=GS A0A511Z314_9BACL/67-163 AC A0A511Z314.1
#=GS A0A0A5GDY8_9BACI/184-282 AC A0A0A5GDY8.1
#=GS A0A3P5WV53_9BACL/532-621 AC A0A3P5WV53.1
#=GS A0A1Y1CKK9_9BACT/477-553 AC A0A1Y1CKK9.1
#=GS A0A6L9Y742_9BURK/98-188 AC A0A6L9Y742.1
#=GS H8H3H8_DEIGI/244-323 AC H8H3H8.1
#=GS A0A438MBJ7_9ACTN/2001-2076 AC A0A438MBJ7.1
#=GS A0A085WHT1_9DELT/393-493 AC A0A085WHT1.1
#=GS A0A1H9UMA2_9BACI/484-591 AC A0A1H9UMA2.1
#=GS A0A1M6J9M4_9CLOT/92-177 AC A0A1M6J9M4.1
#=GS A0A3D8IK51_9HELI/179-271 AC A0A3D8IK51.1
#=GS A0A0G2ZIG5_9DELT/440-540 AC A0A0G2ZIG5.1
#=GS A0A235B799_9BACL/324-421 AC A0A235B799.1
#=GS A0A8J2YDB4_9BACL/278-361 AC A0A8J2YDB4.1
#=GS A0A077EFA4_9FLAO/447-544 AC A0A077EFA4.1
#=GS A0A562NU39_9RHOB/572-674 AC A0A562NU39.1
#=GS H7ELU8_9SPIR/116-212 AC H7ELU8.1
#=GS A0A2N7WGQ3_9BURK/143-237 AC A0A2N7WGQ3.1
#=GS A0A1G7FKC5_9BURK/183-285 AC A0A1G7FKC5.1
#=GS A0A1H8I1H6_9BACI/181-278 AC A0A1H8I1H6.1
A0A1H9WL48_9CORY/221-313 ..............................................................................i-PFNDRG..FP.EFD...S...V..V..-V..E..LP..A..T..A---.....................DGAT.SVT.RGDF.T....L.P.SE.L.HE.S...TVYQQE...............kWL......D......S........Q......MGIT..........AE..........QR..........S....A............KGW....TWHHH.E..........D......L.....G......R.....MQLVPSSV.HG.D.V..R.HTG..........
A0A521DMS3_9BACL/365-461 ............................................................................vpf----KNG..FP.NFD...K...W..S..AIelK..LP..E..E..TWFK.....................SDVV.QFR.ALNR.K....V.Y.QR.A.QS.D...PNLKEQ................FT......D......E........E......LEKL..........KN..........GE..........N....I............NRF....TWHHH.Q..........Q......P.....G......K.....MQLVLRDV.HG.Q.V..R.HTG..........
A0A1C0Y6X3_9BACL/188-284 .........................................................................qmisdv-------..FP.VFE...A...A..F..TA..R..LA..P..D..EYLL.....................TDEE.HDE.IANA.Q....L.Y.KA.I.LE.D...TAIGEIi..............gLS......A......D........D......IEAL..........RQ..........GQ..........T....P............AGY....TWHHH.E..........Q......P.....G......T.....LQLVDAKT.HA.Q.T..E.HVG..........
A0A2W1LEH5_9BACL/40-156 ..............................................................................v-EYDPIG..FP.VFK...N...F..I..KT..D..VN..I..S..NDSLllkngglsk..tvsrlhlqaaTSVL.KER.MEKA.A....N.N.KK.I.DL.E...TYINQQ...............gFT......K......E........Q......AKQI.........iKE..........KD..........K....I............EGY....NWHHH.Q..........E......T.....G......R.....MQLVIQEV.HD.A.H..R.HTG..........
A0A1X9SRT5_9PROT/86-182 ............................................................................ngn---EIKG.vFP.EFK...S...V..F..DA..Q..LP..D..E..LEQA.....................SDSE.QFK.ECNK.Q....L.Q.EA.I.EN.V...PELASK................FT......D......E........Q......LEQV..........KN..........GD..........T....P............DGY....TWHHN.E..........E......K.....G......K.....MQLVDSEI.HA.K.T..G.HTG..........
A0A6I1E8L0_9RHOB/9-81 .................................................................dagyvnafgdvfde-------..--.---...-...-..-..--..-..--..-..-..----.....................----.---.----.-....V.Q.AE.F.QS.N...PGLRQQ................FN......D......D........Q......LKAL.........eAG..........SA..........K....I............PNY....TWHHH.Q..........D......A.....G......R.....MQLVRQRL.HN.Q.T..G.HIG..........
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