#=GF ID Colicin_M
#=GF AC PF14859.10
#=GF DE Colicin M
#=GF AU Eberhardt R;0000-0001-6152-1369
#=GF SE Jackhmmer:P05820
#=GF GA 27.00 27.00;
#=GF TC 27.40 36.40;
#=GF NC 25.20 25.20;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Family
#=GF CL CL0091
#=GF RN [1]
#=GF RM 16777846
#=GF RT Colicin M exerts its bacteriolytic effect via enzymatic
#=GF RT degradation of undecaprenyl phosphate-linked peptidoglycan
#=GF RT precursors.
#=GF RA El Ghachi M, Bouhss A, Barreteau H, Touze T, Auger G, Blanot D,
#=GF RA Mengin-Lecreulx D;
#=GF RL J Biol Chem. 2006;281:22761-22772.
#=GF DR INTERPRO; IPR028056;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC Colicin M is a toxin produced by, and active against,
#=GF CC Escherichia coli. It catalyses the hydrolysis of lipid I and
#=GF CC lipid II peptidoglycan intermediates, therefore inhibiting
#=GF CC peptidoglycan biosynthesis and leading to lysis of the bacterial
#=GF CC cells [1].
#=GF SQ 11
#=GS A0A1T4SQU4_9HYPH/400-568 AC A0A1T4SQU4.1
#=GS A0A2P7B098_9HYPH/10-193 AC A0A2P7B098.1
#=GS A0A0B1YJS9_9BURK/170-346 AC A0A0B1YJS9.1
#=GS A0A0G4K125_9GAMM/114-271 AC A0A0G4K125.1
#=GS A0A0B6RY11_BURPL/188-354 AC A0A0B6RY11.1
#=GS Q88A25_PSESM/72-276 AC Q88A25.1
#=GS A0A3D8JSR1_9BURK/214-385 AC A0A3D8JSR1.1
#=GS A0A6I4U1Z4_9SPHN/1-128 AC A0A6I4U1Z4.1
#=GS A0A103EEW7_9BURK/199-357 AC A0A103EEW7.1
#=GS A0A014NSQ6_9GAMM/23-273 AC A0A014NSQ6.1
#=GS A0A6B3NX71_9PSED/9-173 AC A0A6B3NX71.1
A0A1T4SQU4_9HYPH/400-568 .......................................vepppgspdyerat-------------------------------------------------------------------..----------------------------------------------------------R.ELLPEVADPFSGLAHWLFGRGEPVRYRFDDIDTsS.VRPEQ.....FSEVQRILN.EGK.P..G..TYKIE.G.TKP.....F.W..AGNR-FNSRFFVGNITLKMDGKLVLREDGSYSFEGKLSA.L.PDRYRMYGGSHRKEIDEDVTRIGEALGSL-GHRDYTVFILGEKPISSSGK-h...
A0A2P7B098_9HYPH/10-193 ..........................................dkkntpldiin-------------------------------------------------------------------..-----------------------------------------GVKSTPESAKTYDKADA-.TLSGGIASPFKALAHYLKGDGQTLTVALDQVGL.N.LTPDEvtldeVNQLNQYTEdQNF.V..G..TKHII.VnRFN.....H.N..TADDNAIAAMYLGNILLKLEGDITRHQDGTWNFQGEVRA.W.NDTYDFNSSDHRGMMQEVFT----RTVNVLPGTSYDIAMPGSIPV------swtg
A0A0B1YJS9_9BURK/170-346 .........................................lfgiyanqlngi-------------------------------------------------------------------..-----------------------------------------------------RPTSEF.QFYGNPFMFIGAVYYWVFGNGERRSINLESMNL.R.MGVSD.....FELIRSSID.NPG.YgpG..TYPID.G.PFSt..nvF.S..HGAQDFWSATTVGRVSGHVRGTLTMQEDNTYRFAGSYTL.N.PDKFDADRS-NRPFLQEWMTTVLREIGSTLGHTDYQIYFTGEKEISFSGQR....
A0A0G4K125_9GAMM/114-271 ...............................................fdgsds-------------------------------------------------------------------..----------------------------------------------------------E.QLASGLLAPIDAFRHYLFGDGSDRYVNIDDIGL.N.IEINQ.....IPSVMDIIN.SNA.I..G..SFDIS.N.DFN.....R.N..TSLDGFIPAAYLGNITMKTEGTLNISPDGSWNYNGVIRA.Y.NDRYDANPSTHRDALGEWST----SILETLSGTPYDISIPGELEISGNGKR....
A0A0B6RY11_BURPL/188-354 ...........................................qgfylpvsef-------------------------------------------------------------------..-----------------------------------------------------------.KFYGSPFTTLSSIYYWLFGNGATTTMNLNAMNL.D.VNIND.....FGPVFEIIG.NPD.M..GpgTYNID.A.EFS.....F.NlfNHASNLWTALVNGRVSGHVVGTLVLNGDESYAFNGEWTL.N.PDRYEAYPS-NRTFTQEVLTSFLSRIGSLGH-VDYDILFTGSKEVNLSG--pr..
Q88A25_PSESM/72-276 fgiqskvalktfaaadqreaegrdlrtayneiatdigrsqqineniikyppgn-------------------------------------------------------------------..----------------------------------------------------------H.VLSGGLMTPFHALAHGMFGLGAPLTFPIQNVGL.N.VDIRG.....IPDVMNVIQ.SARpV..G..TSSLD.V.NFA.....Y.D..VGKDSNASWLTLGNITLRLVGTIDKNASGAWTFSGEIRA.F.NDVYDANPSNHRGWLGENLTSLLS----AVPFTSYSIEIPGSLPVTVSG--n...
A0A3D8JSR1_9BURK/214-385 ...........................................yfsqhantpi-------------------------------------------------------------------..--------------------------------------------------------SEF.KFYGNPFMPIAAIHYWINGNGADRTIDIPSLNL.S.MGLND.....FSPIKNIVN.NLS.M..G..PGSYA.I.DASfstnlF.A..HGTKDLWAAGVIGRISGQVTGTLNIDQAGTYAFNDSYTL.L.PDVFNADR-SHRPFPQEQMTDFLRAIGDLFGHTDYTIKFSGSGSISFSG--pr..
A0A6I4U1Z4_9SPHN/1-128 .......................................mqkiaanpdsklgk-------------------------------------------------------------------..-----------------------------------------------------------.---------------------------------.-.-----.....--AIKAAQE.TGK.A..Q..PFTANdI.RNG.....V.T..FGETSFSTQGGVGRIPLDVAGTVAISENGRWELSGTVTA.RgADIQDYPNDPSRGIVGNSINNALGAAQRVFGGKDYRIDFYGSQTI------rawe
A0A103EEW7_9BURK/199-357 ............................................frfyatpff-------------------------------------------------------------------..-----------------------------------------------------------.--------TLAAYDYWFRGNGASRTVDLPSLRL.G.IGVKQ.....IDAIKNIVV.NDG.M..GpgVYPID.A.VFS.....TnL..ISENEWIVGAALGRVSGHVTGQLTLAANGGYSFLGEYTL.N.PDKFDFDASRSRPDVQERLTTLVRKLGEIAGHTDFTIYFNGSQKVDESGTR....
A0A014NSQ6_9GAMM/23-273 ..............................psggasggsivggpppqaqlaid------------------------------------------------FQSGNYYNRALTALSKILKstKFEVEKQK-NAIIFLRDCIF--LNKCMVEQPNNGTYIAQG--W--NSKQRLDMRLDQGIpTLGNNPYAIISALNNYLTGNGRGMSIDISTLAL.QfLKPND.....IPGFNERMNsTGR.P..G..QHNMT.F.SFP.....Y.N..TAGTNVFMPYILGNITLQLDGVFTRNASGSWGFNGVIRAqV.PDLYNFNASTHRSKTNEDLTTFGRWLGERFNGVPFEIQINGQTPV------nf..
A0A6B3NX71_9PSED/9-173 .......................................pvihesmvsyptks-------------------------------------------------------------------..----------------------------------------------------------H.VFSGGVLTPFHALAHSISGKGEPVIFPVGSIGL.N.VKLPS.....VRPFMDAVN.AKG.K..G..VHKID.V.KFT.....H.D..VRKDSLQSGWALGNITLRVVGNVKVAEDGAWIFDGELRA.Y.DDLYDANASTHRDWIGESATSFLRSVM----QTPYTIKMPGVISVKAG---gq..
#=GC seq_cons ............................................h..t.sstp.................................................................................................................................ph.us.hsshsAltaalhGsGtshohslsslsL.s.lplsp.....hsslpshls.sst.h..G..sasIs.s.sFs.....a.s..supsshhsuhslGpIoh+lsGslslstsGoasFsGplpA.h.sDhYDhssSsHRshlpEshTshlptlsphhstTsYsIthsGstsls.uG......
//
