#=GF ID Colicin_immun
#=GF AC PF09204.14
#=GF DE Bacterial self-protective colicin-like immunity
#=GF PI ColicinD;
#=GF AU Sammut SJ;0000-0003-4472-904X
#=GF SE pdb_1v74
#=GF GA 22.00 22.00;
#=GF TC 22.10 22.00;
#=GF NC 21.60 21.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 15014439
#=GF RT Structural inhibition of the colicin D tRNase by the
#=GF RT tRNA-mimicking immunity protein.
#=GF RA Graille M, Mora L, Buckingham RH, van Tilbeurgh H, de Zamaroczy
#=GF RA M;
#=GF RL EMBO J. 2004;23:1474-1482.
#=GF RN [2]
#=GF RM 11741540
#=GF RT Crystal structure of colicin E3: implications for cell entry and
#=GF RT ribosome inactivation.
#=GF RA Soelaiman S, Jakes K, Wu N, Li C, Shoham M;
#=GF RL Mol Cell. 2001;8:1053-1062.
#=GF DR INTERPRO; IPR015287;
#=GF DR SCOP; 1v74; fa;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Colicin D, which is synthesised by various prokaryotes, adopts
#=GF CC an antiparallel four helical bundle fold: the helices are
#=GF CC tightly packed, forming a compact cylindrical molecule. The
#=GF CC protein specifically cleaves the anticodon loop of all four
#=GF CC tRNA-Arg isoacceptors, thereby inactivating prokaryotic protein
#=GF CC synthesis and leading to cell death [1]. This family also
#=GF CC contains immunity proteins to klebicins and microcins. Many
#=GF CC bacteria produce proteins that destroy their competitors.
#=GF CC Colicin D is one such. The immunity proteins are expressed on
#=GF CC the same operon as their cognate bacteriocins and protect the
#=GF CC expressing bacterium from the effects of its own bacteriocin
#=GF CC [2].
#=GF SQ 107
#=GS D9TTP6_THETC/2-90 AC D9TTP6.1
#=GS A0A398B2E9_9BACI/1-86 AC A0A398B2E9.1
#=GS A0A401ILS4_APHSA/1-86 AC A0A401ILS4.1
#=GS C8PL91_9PROT/1-86 AC C8PL91.1
#=GS A0A2S0P8M6_9NEIS/1-88 AC A0A2S0P8M6.1
#=GS E8U7Q6_DEIML/126-207 AC E8U7Q6.1
#=GS K0EZG6_NOCBR/12-94 AC K0EZG6.1
#=GS A0A2A2M270_9BILA/1-87 AC A0A2A2M270.1
#=GS A0A433XKM1_9HYPH/11-88 AC A0A433XKM1.1
#=GS A0A2N5ESI8_9GAMM/1-86 AC A0A2N5ESI8.1
#=GS A0A1Q9PGE7_9BACI/1-86 AC A0A1Q9PGE7.1
#=GS A0A250V8L0_STROL/184-267 AC A0A250V8L0.1
#=GS A0A345XZ05_9ACTN/134-219 AC A0A345XZ05.1
#=GS L1NRH0_9NEIS/4-90 AC L1NRH0.1
#=GS A0A073IVH1_9BACT/9-96 AC A0A073IVH1.1
#=GS A9WIB5_CHLAA/1-86 AC A9WIB5.1
#=GS S6A1G0_9SPIR/1-84 AC S6A1G0.1
#=GS A0A398BET6_9BACI/2-53 AC A0A398BET6.1
#=GS A0A4P7JS81_9GAMM/45-127 AC A0A4P7JS81.1
#=GS A0A231H7J6_9NOCA/1-84 AC A0A231H7J6.1
#=GS A0A2Z4FN80_9DELT/16-99 AC A0A2Z4FN80.1
#=GS A0A1H8XQ76_9PSEU/1-79 AC A0A1H8XQ76.1
#=GS A0A1I4I3M5_9BURK/5-89 AC A0A1I4I3M5.1
#=GS A0A0A2WEK8_9GAMM/73-158 AC A0A0A2WEK8.1
#=GS A0A2A7MXE4_MYCAG/20-102 AC A0A2A7MXE4.1
#=GS B3ETD1_AMOA5/12-101 AC B3ETD1.1
#=GS A0A4U0PCY0_9NEIS/1-85 AC A0A4U0PCY0.1
#=GS A0A2D1U5G8_9SPHI/10-69 AC A0A2D1U5G8.1
#=GS A0A2Z6B183_9DELT/5-87 AC A0A2Z6B183.1
#=GS D4DTX5_NEIEG/4-90 AC D4DTX5.1
#=GS A0A377HUL1_9PAST/1-82 AC A0A377HUL1.1
#=GS A0A1A5PDC8_9ACTN/56-139 AC A0A1A5PDC8.1
#=GS A0A1Z5HDD9_9GAMM/1-85 AC A0A1Z5HDD9.1
#=GS A0A7I7MSF4_9MYCO/11-94 AC A0A7I7MSF4.1
#=GS A0A3M2KZP9_9NOCA/13-96 AC A0A3M2KZP9.1
#=GS A0A084ZP84_9ENTR/1-86 AC A0A084ZP84.1
#=GS A0A318SDV4_9DEIO/123-204 AC A0A318SDV4.1
#=GS A0A848KLJ5_9NOCA/17-97 AC A0A848KLJ5.1
#=GS A0A6L3V8A4_9BACI/1-77 AC A0A6L3V8A4.1
#=GS A0A543IZB0_9ACTN/1-78 AC A0A543IZB0.1
#=GS A0A840Q8X0_9PSEU/12-96 AC A0A840Q8X0.1
#=GS A0A0U3MRU2_9BURK/1-86 AC A0A0U3MRU2.1
#=GS A0A7G1KDR1_9NOCA/12-95 AC A0A7G1KDR1.1
#=GS A0A1B8PK81_MORNO/1-86 AC A0A1B8PK81.1
#=GS A0A1S8CG90_9GAMM/1-85 AC A0A1S8CG90.1
#=GS A0A072NDD6_9DEIO/132-213 AC A0A072NDD6.1
#=GS A0A4R0NL97_9SPHI/11-100 AC A0A4R0NL97.1
#=GS D8G6M9_9CYAN/1-84 AC D8G6M9.1
#=GS A0A4R8DBZ4_9BACT/9-93 AC A0A4R8DBZ4.1
#=GS A0A250KTG1_9GAMM/1-87 AC A0A250KTG1.1
#=GS A0A0F7JNR1_9DEIO/132-213 AC A0A0F7JNR1.1
#=GS A0A841I0L2_9DEIO/122-203 AC A0A841I0L2.1
#=GS A0A2T6CVL3_9BACT/20-102 AC A0A2T6CVL3.1
#=GS D6YWQ0_WADCW/130-210 AC D6YWQ0.1
#=GS A0A178WS95_9PSEU/11-93 AC A0A178WS95.1
#=GS H8GZA0_DEIGI/133-213 AC H8GZA0.1
#=GS W7S7V7_9PSEU/114-199 AC W7S7V7.1
#=GS A0A4R6V4Y8_9ACTN/3-86 AC A0A4R6V4Y8.1
#=GS A0A1X0UNE8_9NOCA/172-254 AC A0A1X0UNE8.1
#=GS H5WPA8_9BURK/4-89 AC H5WPA8.1
#=GS A0A2S0P9F3_9NEIS/1-88 AC A0A2S0P9F3.1
#=GS A0A1U7NUE3_9DEIO/131-212 AC A0A1U7NUE3.1
#=GS C1CW56_DEIDV/133-214 AC C1CW56.2
#=GS A0A221SWM4_9DEIO/133-213 AC A0A221SWM4.1
#=GS A0A4S4AU42_9RHOO/4-88 AC A0A4S4AU42.1
#=GS E4NLH8_HALBP/32-116 AC E4NLH8.1
#=GS A0A6B3SYX5_9BURK/39-128 AC A0A6B3SYX5.1
#=GS A9I257_BORPD/1-88 AC A9I257.1
#=GS A0A1K2HXJ0_9HYPH/9-87 AC A0A1K2HXJ0.1
#=GS S2XJ62_9BACL/1-86 AC S2XJ62.1
#=GS Q74PL1_YERPE/1-32 AC Q74PL1.1
#=GS A0A8J3CDK0_9PSEU/102-187 AC A0A8J3CDK0.1
#=GS A0A0N0EC73_9BACI/1-77 AC A0A0N0EC73.1
#=GS A0A2Z3JF53_9DEIO/132-213 AC A0A2Z3JF53.1
#=GS A0A543NLU7_9ACTN/5-86 AC A0A543NLU7.1
#=GS A0A164HB01_9NOCA/6-89 AC A0A164HB01.1
#=GS A0A2A2TEA8_9CYAN/1-84 AC A0A2A2TEA8.1
#=GS A0A0C1XJV8_9ACTN/194-278 AC A0A0C1XJV8.1
#=GS A0A1W1VDN8_9DEIO/142-223 AC A0A1W1VDN8.1
#=GS W1J8M4_9GAMM/1-88 AC W1J8M4.1
#=GS A0A2K8PGK3_STRLA/23-107 AC A0A2K8PGK3.1
#=GS M1WM04_PSEP2/2-84 AC M1WM04.1
#=GS A0A5C5WA86_9BACT/1-86 AC A0A5C5WA86.1
#=GS A0A1I2HP44_9BACT/1-81 AC A0A1I2HP44.1
#=GS A0A3A9ZJL4_9ACTN/30-113 AC A0A3A9ZJL4.1
#=GS A0A2S9PGT3_YERPE/1-87 AC A0A2S9PGT3.1
#=GS A0A2D1U7L9_9SPHI/1-94 AC A0A2D1U7L9.1
#=GS A0A7K0D4P1_9NOCA/14-99 AC A0A7K0D4P1.1
#=GS A0A498QPT7_9MYCO/11-94 AC A0A498QPT7.1
#=GS L0A452_DEIPD/123-204 AC L0A452.1
#=GS A0A0F4QH66_9GAMM/6-88 AC A0A0F4QH66.1
#=GS A0A1B8QBN1_9GAMM/1-86 AC A0A1B8QBN1.1
#=GS A0A080K9F3_9GAMM/1-87 AC A0A080K9F3.1
#=GS A0A1Q9UFF7_9NOCA/1-71 AC A0A1Q9UFF7.1
#=GS A0A290ZSU6_9RHOO/1-88 AC A0A290ZSU6.1
#=GS Q9RTD3_DEIRA/129-210 AC Q9RTD3.1
#=GS A0A0M1NTZ4_9BACI/1-86 AC A0A0M1NTZ4.1
#=GS D7CRE7_TRURR/128-209 AC D7CRE7.1
#=GS A0A318JML8_9BURK/1-87 AC A0A318JML8.1
#=GS A0A172T9Q5_9DEIO/142-223 AC A0A172T9Q5.1
#=GS A0A840RDM6_9NEIS/5-90 AC A0A840RDM6.1
#=GS A0A399F926_9DEIN/145-230 AC A0A399F926.1
#=GS A0A829YAA4_9GAMM/5-91 AC A0A829YAA4.1
#=GS A0A1H3G3Z8_9PSEU/1-86 AC A0A1H3G3Z8.1
#=GS A0A0L6VXX0_9BURK/4-89 AC A0A0L6VXX0.1
#=GS A0A1T0B228_9PAST/1-82 AC A0A1T0B228.1
#=GS A0A164MGS4_9NOCA/8-91 AC A0A164MGS4.1
D9TTP6_THETC/2-90 ....kavec---.-LVELANKYLIGEIDAKSFSEKFESYFYETEE--AIY.DYDKKIYNVLDNIREAIAYYE.SDAN...I...REK...T.K...YLi.....gDDELNHKVKINLEKL............................
A0A398B2E9_9BACI/1-86 .....mfay---.KYKRLMRDFINETITVEDFERDYLNTFKNETE-----.RMDNTLFGILNGVFEAVDCYW.HERL...R...GQE...T.A...FEi.....sEQQLRKEVSEALV--kf..........................
A0A401ILS4_APHSA/1-86 .........MDIeNYQSMIQAFVDGRLPIQEFETQYLAAFKSQST-----.GMNPELFQLLDSLFSDVDAYS.PDCL...P...EEE...T.P...FIi.....sALSLYKQAAITLEKL............................
C8PL91_9PROT/1-86 ......mie---.EYIKIIEDFLQNRIDVFEFEKIYWDKFMNDKN-----.-FPDEYYEPLNRLLTDIDEFE.PDEE...L...RGD...D.T...VGds...lsEEDLRECAKRALKQ-i...........................
A0A2S0P8M6_9NEIS/1-88 .........MSA.TLLDLAKSFIDGKISAPAFSDIYIDLWRMERDSGAIQ.NDEPHLSECLSSIFCAADMYC.ADDE...A...REE...Y.E...FN.......DVQLKNEILSIIDR-c...........................
E8U7Q6_DEIML/126-207 .....nvep---.-YKRLMQDFLDGRLNEWAFQDQYVTMFRDDAS-----.LRSQAEFELLSRLFGDPDAYH.GGLH...-...QLG...A.P...AE.......RGDLRGRVQELLAQL............................
K0EZG6_NOCBR/12-94 ......ltl---.-YEDILRRFISGEIDAPTFESEYLTTFKSEKT-----.RFGPPVFDLLDALFADVDDYV.ADAQ...L...RAE..aG.G...LD.......DEQLRQRASATYRRL............................
A0A2A2M270_9BILA/1-87 .........MSM.DLIDLAKSFIRSEITADNFEAQFFEIWYQKGTSGLLA.QDTQEIKDCLYELFDFAERYT.SDAD...-...KKD...Y.E...LD.......QETLSSEINKTLTR-c...........................
A0A433XKM1_9HYPH/11-88 .......wa---.---SLMADFIDGAMDGVAFERAYLEASRA------AV.EAGDRVPYAADLMFYEVDAFC.ADPA...L...RGE...G.D...LD.......EAGLRQAARELVRRL............................
A0A2N5ESI8_9GAMM/1-86 .........MSH.ELLKFAKRFVSGEISADSFADPYQAMWKREGNNGLLL.QDDPALSEKLSTIFCLADQYN.PDSD...-...RHP...S.E...FG.......ADELKKRIEDVIA--q...........................
A0A1Q9PGE7_9BACI/1-86 .....mlek---.KYKELMEKFLDEKMSADEFQTQYLRKFNEWND-----.RMYKTQFEILNGVFEAADCYW.HECL...P...GQE...T.A...FEi.....sEQQLRKEVNEALIKL............................
A0A250V8L0_STROL/184-267 ......ghq---.--LELMRQLVTGAIDGPLFARQWLEARRRSMD--AGE.RVGNALITALDEVFYALEDYS.IDPS...L...RDE...D.D...LT.......DEELRERVADALARL............................
A0A345XZ05_9ACTN/134-219 ......sth---.EQLRLMQSMASGEITAPEFAQEWQGARRRAM--EQGE.RVTTPLEDALDRVFYAIEDYS.FSPE...L...QEP...G.D...LT.......DEDLLTEVAEALNQL............................
L1NRH0_9NEIS/4-90 ......msp---.-LLCLATDFIDDKIDADTFVDAYMEMWRSNAS-DFGG.GEQWDRADIAGSLYIIADRYC.PL-E...F...REDiepW.E...LD.......EHELKQAVSIFLN--s...........................
A0A073IVH1_9BACT/9-96 .......ag--I.QFKEMCEKLVAGELSAKDFAHQYLDLWDGEYD----Q.ISEWEYNTYLDDLIMSVSLYE.PDPN...V...YEA...E.K...EDgl...lnDDALLADVKKYLE--vy..........................
A9WIB5_CHLAA/1-86 .........MTLtEYKRLIEAFLTHEISAAEFEERYMAAFLAEPG-----.GMDKELFLILDALFAAVDCYW.PGCA...P...GEE...T.P...FEi.....sEEQLRREARDALARL............................
S6A1G0_9SPIR/1-84 .........MSVdKYIKLITKFIDNAIDAKEFEQSFLEMFKTEQE-----.KISEKDYLVLDSLFGDVDMFC.FDSE...L...FEE...G.D...LT.......ESDLRKSAEQTLERL............................
A0A398BET6_9BACI/2-53 kqkewahii---.-------------------------------------.-------RNLKRSFEAVDCYW.HECL...P...GQE...T.A...FEi.....sEQQLRKEVNEALVKL............................
A0A4P7JS81_9GAMM/45-127 .....medd---.-FKSLVISFLKEQLTETEFMTSFIKLWNESRDSGALS.GSDPVVTRILDRIFTSCDAFE.LNPE...-...---...-.-...--.......---------------ppfeigaiefkaevkdma..........
A0A231H7J6_9NOCA/1-84 .....mldg---.-YEDIIRKFSSGQISADEFESSFLAKFKHDQN-----.QVPSREFEILDSLFADVDEYV.ADAE...L...RES...VgG...IS.......ADVLRDRA-------qsvyrrl.....................
A0A2Z4FN80_9DELT/16-99 .....aalp---.-LVAIVDSFVKRSLSPEEFERTYLRAFLDQGR----Q.PLDDREYDILGELFFAVEDYC.RYPA...I...RDE...T.D...LD.......EIELYNRACLALSRL............................
A0A1H8XQ76_9PSEU/1-79 .......mg---.----LIDRFVGREIDAEQFEAEYLRM--VKDD-E-VI.-HGDPAFGVIDELFFHIDEYFvPPGT...S...ADD...R.A...RQ.......EEALRARACTARQK-l...........................
A0A1I4I3M5_9BURK/5-89 .....yaif---.--SKLLASYLNHELSLPDFQRIFIARFKAESL-----.ALDEPLFLLLDELFAVLDSYT.DDMEllaS...DPS...Y.Y...LD.......EPGVERKAAEI----aarm........................
A0A0A2WEK8_9GAMM/73-158 ......rva---.KYLDLMRAFLGCAITANQFQASYLQTFKADDS-----.KFSAMEYEILNRVFCDADCYT.TDVQ...L...RAE...K.PeilID.......EAELRRNVAVALG--dl..........................
A0A2A7MXE4_MYCAG/20-102 ......tsg---.-YFRLIDDFIAGRMTAPEFQKSFLIALKFENR-----.GLDDRLFDVLQRLFEDTDDYV.AYPE...L...RTD..pE.D...LD.......DEQLRECAI------rarrel......................
B3ETD1_AMOA5/12-101 .....ihlq---.KYIYLLGLFVSNQIDISSFEDLFLKI--RREDNYWLSgLFNNKIGKVLDSLFLDVDEYT.PDCL...F...DPN...N.K...FTi.....nETELKKRASESLNTL............................
A0A4U0PCY0_9NEIS/1-85 .........MSA.ALFEFARSFVVGRLSAEIFSSAYMELWKIERDRGFLQ.KDDSELNEKLSSIFCLADLYN.PDPD...-...REG...Y.E...LD.......EESLRIKITQIV---g...........................
A0A2D1U5G8_9SPHI/10-69 .....ihlq---.KYLHLLSLLCSAKIEVAEFEELFMQI-K-ADDEYWRSgMFDQKIAEVLDALFLDIR---.----...-...---...-.-...--.......---------------dy..........................
A0A2Z6B183_9DELT/5-87 ......hiy---.TYIDIIRCFTRHRINAKDFANVYTIIYLRCSG-----.KMKHEEYEALNNLYYYVEDYY.DDPS...M...RDE...G.D...PD.......ETKLLKEAAETLHKL............................
D4DTX5_NEIEG/4-90 ......msp---.-LLCLATDFIDDKIDADTFVDAYMEMWRSNAS-DFGG.GEQWDRADIAGSLYIIADRYC.P-LE...F...RED...I.E...LWe....ldEHELKQAVSIFLN--s...........................
A0A377HUL1_9PAST/1-82 .......mt---.ELLKLAIDFHNKKISVNEFQELYLDKWNGGTK---GA.TQDEQNKEI--SIYYATECYN.PNGI...Y...LHN...G.E...ID.......EVQLRKEIAEHLREL............................
A0A1A5PDC8_9ACTN/56-139 .....aarq---.--LALLEAFTDGTCSAPDFAHGWWEA--RRASQANGE.RVQGALGALFDQVFMILEDYS.IDPN...F...AEP...G.D...LD.......DAELQTTVRA-----vwag........................
A0A1Z5HDD9_9GAMM/1-85 .......ms-TIeKYILLMTQYITGEIPAFQFEVAYLEMFIEETR-----.FLSEDVYDALNNLFLDVDAYC.GDVS...L...RDD...E.D...LD.......EEDLVASVKEALKKL............................
A0A7I7MSF4_9MYCO/11-94 .........MTA.KYRELISSFINREISAQHFESSYLALFKHGKD-----.QFPGPEFNVLEGLFFDVDDYV.ADPE...L...RRD...VhG...LD.......DEELRACAREAYRK-l...........................
A0A3M2KZP9_9NOCA/13-96 ......mld---.RYEEVIRRFVTGETTADEFESDYRQLFANDPE-----.KVESSEHQALEGLAAEVDDYI.SDPE...T...RDQ..iG.G...LD.......GDALRACARATYR--rl..........................
A0A084ZP84_9ENTR/1-86 .........MSY.LLVEFARSFGSGRLSAVAFAEAYMELWRIERDNKNIL.NYDESVSECLSSVFCAADMYN.PDDD...-...REE...Y.E...FD.......DEQLRNEINKLM---di..........................
A0A318SDV4_9DEIO/123-204 .....nvep---.-YKLLMRRYLNGELSDWQFQDTYITMFRDDAS-----.LRSKHEFELLSRLFGDPDAYH.GGLH...-...QLG...A.P...QA.......RGDLKERVADLMAQL............................
A0A848KLJ5_9NOCA/17-97 .......gl---.--LPMIGRFVTGTSTAQEFELEYLIAFKNDVD-----.RWPESQFALLDSLFADVDDYV.ADPA...L...RAE..vG.G...LD.......DDQLRDRARAV----yesv........................
A0A6L3V8A4_9BACI/1-77 ........m---.------EDFINEVITVGDFERDYLRTFKNETE-----.RMDNTLFEILNGAFEAVDCYW.HECP...P...GKE...T.A...FEi.....sEKQLRKEVSEALVRL............................
A0A543IZB0_9ACTN/1-78 .......mr---.-------RYVAGDISGPEFRRAWLQA---RTNALIAGeRVAGRFERILHDVFYALDEYV.PDPE...I...RCP...R.D...LD.......DHLLWGIVNDALLRL............................
A0A840Q8X0_9PSEU/12-96 .....dlqf---.-LIVLIRDFVEHRISADEFESRYLTAFKAGTG----D.VADDDIFETLDGLFADVDAYV.ADPT...L...RTD..pE.D...LD.......EEQLRACAARVLEKL............................
A0A0U3MRU2_9BURK/1-86 .........MSK.NLLMMVETFVSKEITAEVFAEQFIAAWKRERESGDAL.LDSAHLSEKLSSIFCFPDMFN.PAPD...-...KDE...Y.E...LD.......EAQLLAEVTSLI---sg..........................
A0A7G1KDR1_9NOCA/12-95 .......ml--A.VYEPLLRAFVSGELSADNFEAAYLAKFKQDRS-----.QVPGPEFEVLDGLFADVDDYV.ADAV...L...RER..aG.G...LD.......AEQLRDRARAAYTR-l...........................
A0A1B8PK81_MORNO/1-86 .........MSV.LLLNFTKAYLNERINTNCFVDAYIELWRIERDLGLAN.IDDERLNLFLSSIFYIVDLYN.PDSE...-...KEE...Y.E...FN.......DIELYSKISEEL---al..........................
A0A1S8CG90_9GAMM/1-85 .....mnkm---.AIIELAKAFLNSKVTALQFSEDICAV---RRELYGIK.DQDKNTLNCGEELFMVAEIYN.PDSD...-...RAS...Y.E...LD.......EAGLRKEVKATLEK-f...........................
A0A072NDD6_9DEIO/132-213 .....nvep---.-YRRLMRAYLAGELSEWAFQDQYVTLFRDDAS-----.LRSQREFELLSRLFGDPDAYH.GGLH...-...QLG...A.P...QE.......RGDLRERVQALLNEL............................
A0A4R0NL97_9SPHI/11-100 .....ihlq---.KYLNLILLFVSKEITTEFFEKNFLAT--RRNDPYWMSgSFENSISQILDTFFLDVDDYV.PDEL...R...DGT...N.K...LNi.....nEKELLKRAKCTLDKL............................
D8G6M9_9CYAN/1-84 .......me---.KYIKLLQEFVGNTISADEFEQRFIQLFKGDNN-----.LQLGREFKILDKLFADVDAYC.SDPD...L...IED...P.R...FDi.....gEDQLQVSAEETLDKL............................
A0A4R8DBZ4_9BACT/9-93 .....rlyw---.----LIIEYLNQHISARTFCDEFYYCYDLAIDYDTLT.QQEKDGFSSLSEITGRFSEFE.NDIR...K...YPG...T.Y...YT.......EQQLRQKVTETKE--al..........................
A0A250KTG1_9GAMM/1-87 .........MSV.TILEFARSFVDERLSADEFANCYLELWKIERDNNLLQ.QDDDKLSECLSSIFCLADQYN.PDHD...-...RDE...H.E...LD.......AVQLREEVAKLIS--gf..........................
A0A0F7JNR1_9DEIO/132-213 .....nvep---.-YRRLMRAYLDGQLSDWAFQDQYVNMFRDDAS-----.LRSQREFELLSRLFGDPDAYH.GGLH...-...QLG...A.P...QG.......RGDLKARVQELLT--el..........................
A0A841I0L2_9DEIO/122-203 .....nvep---.-YRDLIRRYLNGQLSDAMFQDAYVTLFRDDAS-----.LRGKQEFELLSRLFGDPDAYH.GGLH...Q...L-G...E.P...QS.......RGDLRARASELLQQL............................
A0A2T6CVL3_9BACT/20-102 ......cik---.KYIELIGQYDSGDIDASAFEVLYIRKFKRESI-----.DLPKDVFEELDRLFGDVDAYS.PDDR...D...RVI...G.S...ID.......EGALRMSAKRTLSAL............................
D6YWQ0_WADCW/130-210 ......die---.QYIRLLEEYLEGRMDEQSFTHEWLETFRSDNS-----.LRSTEEFNLLNSLFGDVDMA-.----...-...---...-.-...--.......---------------yasiinegapvcntlkvraesllqqi..
A0A178WS95_9PSEU/11-93 ......aad---.-YGELIGRFVDRTIDAGQFEQQYLDLMKNDEA-----.LHPDDVFAVLDGLFSEVDEYF.VSPE...A...SPA...E.R...RD......lDEALRRHAVAALARL............................
H8GZA0_DEIGI/133-213 ......aep---.-YRRLMHAFLDGQLSEWAFQDQYVTMFRDDAS-----.LRSQREFELLSRLFGDPDAYH.GGLH...-...QLG...A.P...QE.......RGDLKARVQTLLNDL............................
W7S7V7_9PSEU/114-199 .....avae---.-QLDLMRSFADGQTPPADFARRWLAA--RRRSLSEGE.RTRPPLTEILDRMFSALDDYA.IDPT...L...HEP...G.D...LT.......DEQLADVARRALEEL............................
A0A4R6V4Y8_9ACTN/3-86 ....iplap---.-YADLARSYVEGEIEARAFETAFLRLFKTDER-----.LFGPADYEALEELFWAVDSYC.ADPE...L...RDE...R.D...LD.......EPQLRRYVQDFLDR-i...........................
A0A1X0UNE8_9NOCA/172-254 .....qcav---.-FIPTIQNFVNHELSVEDFEAQYLRL---VND--WPA.SLDPAVSGTVNQLFIDIDAFV.SDEA...L...RGC...G.D...LD.......EQQLRLCAQDALSEL............................
H5WPA8_9BURK/4-89 .......al--V.EYARLLEQFLSGAVPAEEFQRAYLGRFKNEQR-----.SLEEPLFEVLDELFGAVDAYT.GDPL...L...LAE...Q.PafyLT.......EDGLRAQVVRAA---grl.........................
A0A2S0P9F3_9NEIS/1-88 .........MSA.TLLDLAKSFVDGEISASDFSDIYINLWRVERDSGIIL.NDEPHLSECLSSIFCAADMYC.ADDE...T...REV...Y.E...FN.......DSQLKNEILSIIDR-c...........................
A0A1U7NUE3_9DEIO/131-212 .....niep---.-YRRLMRDFVDGKVSDWAFQDQYVTMFRDDAS-----.LRSQREFELLSRLFGDPDAYH.GGLH...-...QLG...Q.P...QE.......RGELQDRVKQLLTEL............................
C1CW56_DEIDV/133-214 .....nvep---.-YRRLMRDFVDGRLNEWAFQDQYVTMFRDDAS-----.LRSQREFELLSRLFGDPDAYH.GGLH...-...QLG...A.P...QD.......RGDLRARVQALLQEL............................
A0A221SWM4_9DEIO/133-213 ......lep---.-YRRLMTAYINGELSDWAFQDQYVAMFRNDGS-----.LRSQREFDLLSRLFGDPDAYH.GGLH...-...QLG...A.P...QE.......RGDLKARVQQLLTEL............................
A0A4S4AU42_9RHOO/4-88 .......aa--V.EYGLLLKKFLDGAISVDEFRVTYFDRFKNEGR-----.-LNEPLFNLLDELFGDVDSFT.TDQE...L...LDE...NpEf.yLD.......EKGLREKVQNVANRL............................
E4NLH8_HALBP/32-116 .....tiik---.KYINPLQRYTEGEMSASELSTGYLEEFKNESQ-----.GFSEETYQILQNMFRKSDAYCePEIR...E...DVR...G.S...IG.......EQELLEAATQTIKKL............................
A0A6B3SYX5_9BURK/39-128 ......rvl---.-TINLMNKVINNEIFLEEFSRFYISLFQEETS-----.HFDSNIYDAINSVFLDADEYV.PLAD...-...-EN...Y.K...--.......---------------sleckfpnfliadeefmkrievaikkl.
A9I257_BORPD/1-88 .........MSF.VLLEFAKSFVEGRISAPVFSEAYMELWKIERDSGSLI.RDESALSERLSSIFCAADMYN.SDSE...S...REE...Y.E...FD.......DEQLRFEVCKLVEG-i...........................
A0A1K2HXJ0_9HYPH/9-87 ......pwe---.---RLMQALLDGEMDGPQFQDEFLAA---SRD---AT.ARGERVPYAADLMFYEVDAYC.ADPA...L...RGE...N.D...LD.......EAGLRDAARRLITRL............................
S2XJ62_9BACL/1-86 .........MDVnKYKKLMVDFLEEKMSADEFQTQYFKVFKGSDD-----.IMGKPLFEILNGVFESADCYW.HECL...P...GQE...T.P...FEi.....sEQQLRKEINEALIKL............................
Q74PL1_YERPE/1-32 ........m---.-------------------------------------.----------------ADLYN.PDSD...-...REE...Y.E...LD.......DKQLYEQVLQLINKL............................
A0A8J3CDK0_9PSEU/102-187 ....avadq---.--LTLMTALVTGEISPKSFEMDWYDAWRRERD--SGE.RTHGVLYEALKEMFFFLEDYT.ADAS...L...REP...G.D...PT.......DDDLLRAVREVLT--ll..........................
A0A0N0EC73_9BACI/1-77 ........m---.------KDFIVEVITVEDFERDYLKTFKNETE-----.RMDYTLFDILNGVFEAVDCYW.HECL...P...GQE...T.A...FEi.....sEQQLRKEVCEALVK-i...........................
A0A2Z3JF53_9DEIO/132-213 .....nvqp---.-YKQLMQAYLDGQLPDWEFQERYVNLFRDDAS-----.LRSQREFELLSKLFGDPDAYH.GGLH...Q...LGE...-.P...QA.......RGDLKARVEELLGQ-l...........................
A0A543NLU7_9ACTN/5-86 .....pvap---.-YVELCRQFVRGGMTASCFESLFLVMYKSEMR-----.ELESH-YSDMAELFWAVDAYC.PDPD...I...RDS...S.D...LD.......EEQLRSAARGFVE--av..........................
A0A164HB01_9NOCA/6-89 .....alag---.-YTELISRFVDDRISAQEFESSYLRMFKNEKT-----.RFPVDVFDLLDGLFADVDDYV.ADPD...L...RND..aG.G...LD.......DEQLRTRARRVYDRL............................
A0A2A2TEA8_9CYAN/1-84 .......mk---.KYIILLEDFLSKKIDTNKFEQIFLQIFKDEEI-----.FYSEIEFQVLDKLFGDVDAYC.NDPN...L...IED...P.E...FEi.....tEEELRLSAKKTLDQL............................
A0A0C1XJV8_9ACTN/194-278 .....taeq---.--VSLMEQFAGARISGPAFARSWHAA--RRRSHARRE.RLRAEFEHILDGVFHALEDYA.AEPA...L...TEP...G.D...LD.......DDGLRTVVRERLAAL............................
A0A1W1VDN8_9DEIO/142-223 .....nvep---.-YRRLMRAYLDGQLSEWAFQDQYVTLFRDDAS-----.LRSQREFELLSRLFGDPDAYH.GGLH...-...QLG...A.P...QE.......RGDLKARVSELLADL............................
W1J8M4_9GAMM/1-88 .........MSL.LLLEFSKSFVKGKICAQVFADAYIELWRIERDNNNIL.NYNDKLSECLSSIFCLADMYN.PEQD...D...RLS...Y.E...LN.......DEQLREKVSELIRQL............................
A0A2K8PGK3_STRLA/23-107 .tgrqlslm---.------GDLSRGSVSPPEFAKAWLNC--RRRALNDGE.RVAEALSRRLDQVFYALDDYP.IDPA...F...REA...G.D...VT.......DAELLSVVVTALD--qf..........................
M1WM04_PSEP2/2-84 .....dttn---.IYINLIDDFLHYRITASEFEMSFIRQ--RRQD----L.NDKNNYNNALEELFFDIDAFC.SDPE...L...IEE...E.D...LT.......EEELRRSCMRTLSD-l...........................
A0A5C5WA86_9BACT/1-86 .........MSQ.RLLKFAEDFLQRKTPVEDFVDAYADAWRTERDNNEIL.EDDPITSEKLSTFFCLVDLYK.PDED...-...RED...Y.E...VD.......EAELRLRMQR-----vfdg........................
A0A1I2HP44_9BACT/1-81 ......mse--L.AYKSIIYQFLNHKLTVEEFIDLYMQQWKSDRD---DI.SLDPRFRRLIDRVFTSCDCYR.EAPK...-...-TA...Y.E...ID.......EKDLRNEI-------dlls........................
A0A3A9ZJL4_9ACTN/30-113 ....tvyah---.--LAAIRAFVDGRLTAREFEVIYLNIFKYDPH-----.PHEDSVAMPLERLFAEVDAFV.ADPA...L...RAE...V.G...GS......dEETLRQVARETLA--gf..........................
A0A2S9PGT3_YERPE/1-87 .........MSI.VILEFAKSFINERVSAQVFANAYIEFWRIERDQRICL.KDNEKLNECLSSIFCLADLYN.PDSD...-...REE...Y.E...LD.......DKQLYEQVLQLINKL............................
A0A2D1U7L9_9SPHI/1-94 .........MHLqKYIYLLSLLCTAKIEVSEFETQFMQI--KAGDEYWNSrIFDEKIAQVLDALFLDVRDYS.LDYL...Y...DRN...D.F...INvnlisfnEAEVRIKAQEAL---kn..........................
A0A7K0D4P1_9NOCA/14-99 ....agide---.-QLELMRAVVDGDLTATQFAREWHAAHRRSLN--SGE.KISAQFENVLNEVFYAIEEYA.IDPE...N...KQD...T.D...IS.......DQELISIVRDALA--s...........................
A0A498QPT7_9MYCO/11-94 .........MTA.KYQELISRFINRGISAPEFQSLYVTVFKDDGD-----.QVSGAEFKILDRLFADVDDYT.ADPE...L...RET..aG.G...LD.......DEQLRTCAREAYRKL............................
L0A452_DEIPD/123-204 .....niep---.-YKQLMHQFLNDELNEWQFQEAYVNYFRDDAN-----.LRSQREFELLSRLFGDPDAYH.GGLH...-...QLG...A.P...QS.......RGDLKTRVQELLAQL............................
A0A0F4QH66_9GAMM/6-88 .....wlep---.-YILLVTQFVVGEVTAGQFEASYMDMFKNESR-----.EIPDDIYDVLNDLFSDVDAYC.GDPD...L...RGD...E.D...LD.......ELTLLSRAKEALRKL............................
A0A1B8QBN1_9GAMM/1-86 .........MSL.LLLEFTRTYTNEIIDASCFVEAYIQLWKIENKLGISV.KDEEQLNLFLASIFYIADLYN.PDSD...-...KLD...Y.E...FN.......DEQLFEKVTSE----lls.........................
A0A080K9F3_9GAMM/1-87 .........MSL.IALEFAKSFVNGRITAQVFAEAYIELYRIERDNGLLL.KDEDSVSECLSTIFCLADLYN.PDSD...-...KEE...Y.E...LN.......DKQLIEQIEQELKKL............................
A0A1Q9UFF7_9NOCA/1-71 ....msgks---.--------------GAQDFETRYLALVKKTPG-----.RLDPAVSAAVNQLFTDVDAFV.SDDR...L...RDE...D.D...LD.......EQQLLACAHTALRTL............................
A0A290ZSU6_9RHOO/1-88 .........MSS.ILLEFAKSFVADRLSGKVFSEAYIELWKIERDKNLLQ.EDAPLLSECLSSIFCAADMYC.EDAI...S...REE...H.E...FD.......SDQLKAEISRLIRK-f...........................
Q9RTD3_DEIRA/129-210 ......sve---.PYRQLMQAYLAGQLSDWAFQDQYVTMFRDDAS-----.LRSQREFELLSRLFGDPDAYH.GGLH...-...QLG...A.P...QD.......RGDLKARVQSVLDQL............................
A0A0M1NTZ4_9BACI/1-86 .........MFInKYKQIMVDFLEGNMSADEFQTRYMEIFLKAND-----.KLDEAHFEILNGVFESADCYW.HECL...P...GQE...T.S...SEi.....sEQQLRNEINEALIKL............................
D7CRE7_TRURR/128-209 ......dls---.VYLHLLEQYLSGMIDDRQFEFAYTTTFRDDAS-----.LRSREEVEVLGSIFGDVDRHL.EMHL...-...MMG...G.R...SN.......SDEVRKRAEAAYE--rl..........................
A0A318JML8_9BURK/1-87 .........MSE.KLLRFVEEFLATESNAEVFADEFIKRWKKEGASGLAL.SDNPQLSEVLSSTFCLADMYN.PDAD...-...RES...Y.E...LD.......EHKLRVEIRKLIDG-i...........................
A0A172T9Q5_9DEIO/142-223 .....nvep---.-YRRLMNDFVEGRLSDWAFQDQYVNMFRDDAS-----.LRSQREFDLLSRLFGDPDAYH.GGLH...-...QLG...Q.P...QQ.......RGDLKARVQELLTEL............................
A0A840RDM6_9NEIS/5-90 ........q-SI.NLEKLAQSFSNEDLSAIDFVEKYLSLRRDFLD--KKI.TLSSAAENLMENLFWPVEDFE.PDPE...I...FDKa.dG.H...IE.......ENEFRNRVRAI----li..........................
A0A399F926_9DEIN/145-230 .....nlep---.-YKRLLDAYISGAISEPQFQWNYLNLFREDAS-----.LRSQREFEVLNSLFGNPDEHH.IH--...-...---...-.-...--.......---------------pmtilqferehpqatplyerakelrarl
A0A829YAA4_9GAMM/5-91 ......dlk---.ELLESMRGFVDGRLPAEEFADRYQVLWKRLRDSRSME.SLNPYLQRAIDVVFTAIDD--.ADSP...-...IHG...R.S...LNs.....cEAQLRHDVSV-----vlsvi.......................
A0A1H3G3Z8_9PSEU/1-86 ...msndva---.DYVGLIRAFTSGKISAPRFEEQYMAMFKAATR-----.HFPEPIYEILNDLFLDCDEYV.ADPD...L...RDE...D.D...LD.......DQQLHERATEALTKL............................
A0A0L6VXX0_9BURK/4-89 ......vca---.DYKALLDRFLDGAMPTATFRTLYFKRFKEETR-----.YMSSDLFEVLDGLFADLDGLT.DDPE...LlaaKPD...Y.F...ID.......EARLRARVQAAS---rrl.........................
A0A1T0B228_9PAST/1-82 .......mt---.ELLKLAIDFHNKKISVNEFQELYLDKWNGGTK---GA.TQDEQNKEI--SIYYATECYN.PNGI...Y...LHN...G.E...ID.......EVQLRKEIAEHLREL............................
A0A164MGS4_9NOCA/8-91 ..saafipp---.-----LQDFVEMRISAREFQTRFLELLNKQQG-----.SVDPRVRDPLHFLFCEVDNFA.YRNL...Q...DPN...S.Pn.gID.......EHTFRTSAREALSTL............................
#=GC seq_cons ..............hhpLhpsFlssclostpFpptYlpha+p-ps......thspphhclLsplFtssDsYs.s-sp.......ppp...t.t...h-.......-ppL+pcspphltp.............................
//
