#=GF ID   Conotoxin
#=GF AC   PF02950.21
#=GF DE   Conotoxin
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_529 (release 6.4)
#=GF GA   25.10 25.10;
#=GF TC   25.30 25.20;
#=GF NC   24.80 24.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF WK   Contryphan
#=GF WK   Conotoxin
#=GF CL   CL0083
#=GF RC   Review
#=GF RN   [1]
#=GF RM   3052286
#=GF RT   Peptide toxins from venomous Conus snails. 
#=GF RA   Gray WR, Olivera BM, Cruz LJ; 
#=GF RL   Annu Rev Biochem 1988;57:665-700.
#=GF RN   [2]
#=GF RM   8230223
#=GF RT   Three-dimensional structure in solution of the calcium channel
#=GF RT   blocker omega-conotoxin 
#=GF RA   Pallaghy PK, Duggan BM, Pennington MW, Norton RS; 
#=GF RL   J Mol Biol 1993;234:405-420.
#=GF DR   INTERPRO; IPR004214;
#=GF DR   SCOP; 2cco; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Conotoxins are small snail toxins that block ion channels.
#=GF SQ   16
#=GS A0A815IN49_ADIRI/5-90  AC A0A815IN49.1
#=GS A0A1I2I7Z1_9BACT/2-72  AC A0A1I2I7Z1.1
#=GS A0A1W4WZH9_AGRPL/4-89  AC A0A1W4WZH9.1
#=GS K4JZ61_ARAVE/3-73      AC K4JZ61.1
#=GS A0A1D2NAF4_ORCCI/2-80  AC A0A1D2NAF4.1
#=GS W7XJE7_TETTS/1-74      AC W7XJE7.1
#=GS A0A166MGQ5_9AGAM/4-78  AC A0A166MGQ5.1
#=GS A0A2Z6S4P7_9GLOM/1-78  AC A0A2Z6S4P7.1
#=GS A0A4Y2F7A9_ARAVE/3-71  AC A0A4Y2F7A9.1
#=GS A0A1B8GMV0_9PEZI/1-72  AC A0A1B8GMV0.1
#=GS W7X903_TETTS/35-99     AC W7X903.1
#=GS T0RK02_9PROT/1-74      AC T0RK02.1
#=GS A0A815P8U8_ADIRI/5-90  AC A0A815P8U8.1
#=GS A0A816EJX2_ADIRI/5-85  AC A0A816EJX2.1
#=GS W7X9R5_TETTS/1-81      AC W7X9R5.1
#=GS A0A3P7NZI6_DIBLA/1-73  AC A0A3P7NZI6.1
A0A815IN49_ADIRI/5-90             ..............................v-KLVCVTMIVMLIMAn.sdA--FV.....RSSQLEDDD.AFAEhniNLREVVHRF..AR-KS.DK...CVGRGDDC.-SGGRQCCSK.rTCN..-----wfgigpivryyca
A0A1I2I7Z1_9BACT/2-72             ............................kkl-----VLMLAIVFAFg.vsATYAV.....QVNETKTEQ.VSTA...NKDEKDKKQ..TKKAD.--...---KKEAC.EKSKKECCSKkkSCD..-----dkk..........
A0A1W4WZH9_AGRPL/4-89             .............................sw--LPVVLSILVLLAAv..yPQVHAgpyldEDDYDQLSE.QYSD...N--TLDRML..QPAQK.RA...CIRRGGNC.DHRPNDCCYN.sSCR..C----nlwgsncrc....
K4JZ61_ARAVE/3-73                 ..............................k------LVIAVVFML...lANLVI.....CFEAEGGRS.SFTA...HLSESDTEV..ARAD-.QE...CRKGGERC.-DSAHKCCEG.sSCS..-----vlimgl.......
A0A1D2NAF4_ORCCI/2-80             ...........................mnlr--------VCVVLLAs..lYFCIA.....QYDEEYEEQ.DISF...NGNSLDYSE..DYRDK.RQ...CLGKWARCqYDSGPSCCNG..YCH..-----qdidasygnc...
W7XJE7_TETTS/1-74                 .........................mktsay------LIALLLLLS....TFFLLl...tKQQAKIEDS.NLIN...EVQIPEQPE..SANL-.-K...CIDNFHPC.-SNDHDCCSQ..SCH..LWLC-i............
A0A166MGQ5_9AGAM/4-78             ..........................stvfa-----MLAAATVSVS....AVSTA.....DTNAARLARgLAPK...APTKRDTAR..RSAAS.GE...CKPLLQSC.-AVNSECCAD..LCL..LGLC-g............
A0A2Z6S4P7_9GLOM/1-78             ..............................m-----IFIVSLCFLTl.niEAHYQ.....HQRRSSTAT.TIKS...KRHPTKPKT..NAKSI.NSpkiCVPSGTFCsPNSKPPCCSG..FCY..RHKC-v............
A0A4Y2F7A9_ARAVE/3-71             ..........................qlavp-------LVFILLVN....--LAI.....CFEAESGRS.SFTA...HLSESETEF..AR-AD.QE...CRKEGESC.-DRSHKCCEG.yDCN..-----imil.........
A0A1B8GMV0_9PEZI/1-72             mkfyvaatilaltvgamsvavpegfnealnv---------------....-----.....---------.----...AVREAVTNP..SNSAT.GE...CRPALQSC.-DRNSECCSR..FCL..LGLC-l............
W7X903_TETTS/35-99                ............................kai-------LILLVLVI....LVSMN.....PSSSVQARS.LKAN...----SSAAG..KEQLR.TD...CAAPFASC.--KKKSCCVG..GCT..FGRC-m............
T0RK02_9PROT/1-74                 ............................mkk---VILLFTLVLSIQ....GFAQS.....KGEVPKEVT.AHIA...KLLGLSANN..TKSLT.NN...CSVGGSQC.-IFDNDCCSD..NCL..SGVC-q............
A0A815P8U8_ADIRI/5-90             ..............................v-KLVCVTMIVMLIMAngdvFVRSS.....QLEDDDAFA.EHNI...NLREVIHRF..ARKSD.-K...CVSRGDDC.-SGGRQCCSK.rTCH..-----wfgigpivryyca
A0A816EJX2_ADIRI/5-85             ...............................MKLVYMVTIFVILIL....--MNK.....QVFGKPYES.DEHQ...LGSRETVDR..SVRKS.EK...CAGRGESC.-SGGRKCCSK.rSCE..-----yigfgpvviyycs
W7X9R5_TETTS/1-81                 ........................mrfnlva------LILLVLFVF....SNAHL.....RMAEETQAQ.TETQ...PQAEAETQT..EGKVEpLM...CQRQGQLC.GIGLPSCCSG..LCCnySFGC-qrc..........
A0A3P7NZI6_DIBLA/1-73             ............................mkf-----LLTVLLLGLL...lQVTLA.....KEKPKEEEE.DETK...EVSAAKEEK..EGAVS.PA...CGGWWGGC.--CRRPCCWR..RC-..CRRC-gcg..........
#=GC seq_cons                     ..............................h......hhlhllhlh......hhh.....p.ptpptpp.shst...phppscppt..stpsp.tp...ChsptpsC..sssppCCup..sCp.......h.h..........
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