#=GF ID Csm2_III-A
#=GF AC PF03750.17
#=GF DE Csm2 Type III-A
#=GF PI DUF310;
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE COG1421
#=GF GA 24.80 24.80;
#=GF TC 24.90 28.00;
#=GF NC 24.70 24.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF WK CRISPR
#=GF RN [1]
#=GF RM 17442114
#=GF RT Evolutionary conservation of sequence and secondary structures
#=GF RT in CRISPR repeats.
#=GF RA Kunin V, Sorek R, Hugenholtz P;
#=GF RL Genome Biol. 2007;8:R61.
#=GF RN [2]
#=GF RM 21552286
#=GF RT Evolution and classification of the CRISPR-Cas systems.
#=GF RA Makarova KS, Haft DH, Barrangou R, Brouns SJ, Charpentier E,
#=GF RA Horvath P, Moineau S, Mojica FJ, Wolf YI, Yakunin AF, van der
#=GF RA Oost J, Koonin EV;
#=GF RL Nat Rev Microbiol. 2011;9:467-477.
#=GF DR INTERPRO; IPR010149;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC Clusters of short DNA repeats with non-homologous spacers, which
#=GF CC are found at regular intervals in the genomes of
#=GF CC phylogenetically distinct prokaryotic species, comprise a family
#=GF CC with recognisable features. This family is known as CRISPR
#=GF CC (short for Clustered Regularly Interspaced Short Palindromic
#=GF CC Repeats). A number of protein families appear only in
#=GF CC association with these repeats and are designated Cas
#=GF CC (CRISPR-associated) proteins [1]. This entry represents Csm2
#=GF CC Type III-A, a family of Cas proteins also known as TM1810/Csm2
#=GF CC [2].
#=GF SQ 319
#=GS A0A0A2HVY2_9DELT/15-132 AC A0A0A2HVY2.1
#=GS I0AIU8_IGNAJ/70-183 AC I0AIU8.1
#=GS V2Y5J0_9FIRM/5-129 AC V2Y5J0.1
#=GS A0A1I1VD39_9BACT/42-153 AC A0A1I1VD39.1
#=GS F9N7L8_9FIRM/1-136 AC F9N7L8.1
#=GS A0A252F190_9CLOT/39-166 AC A0A252F190.1
#=GS A0A415RCT3_9FIRM/8-142 AC A0A415RCT3.1
#=GS A0A327YFZ9_9BACI/17-129 AC A0A327YFZ9.1
#=GS R6Q9M4_9FIRM/13-135 AC R6Q9M4.1
#=GS C1DWT0_SULAA/42-154 AC C1DWT0.1
#=GS A0A2H5YYL8_9BACT/33-160 AC A0A2H5YYL8.1
#=GS A0A388T9T8_9BACT/2-73 AC A0A388T9T8.1
#=GS A0A7S7NYD8_9BACT/14-116 AC A0A7S7NYD8.1
#=GS A0A4Y4D1W6_ZOORA/41-157 AC A0A4Y4D1W6.1
#=GS C8NA66_CARH6/21-143 AC C8NA66.1
#=GS A0A7V7ZPS0_9CHLR/30-171 AC A0A7V7ZPS0.1
#=GS A0A0X3U5V8_9GAMM/28-148 AC A0A0X3U5V8.1
#=GS A0A2H5WVB2_9BACT/27-134 AC A0A2H5WVB2.1
#=GS A0A388TFS5_9BACT/1-73 AC A0A388TFS5.1
#=GS A0A3N1UQN1_9DELT/22-133 AC A0A3N1UQN1.1
#=GS A0A2M8T6F5_9CLOT/37-177 AC A0A2M8T6F5.1
#=GS A0A8J3FCL3_9BACI/114-224 AC A0A8J3FCL3.1
#=GS F6BEA8_METIK/35-149 AC F6BEA8.1
#=GS A0A0P6XW01_9CHLR/15-136 AC A0A0P6XW01.1
#=GS A0A062XAP1_9LACO/13-135 AC A0A062XAP1.1
#=GS A0A2V3JBX5_9EURY/19-127 AC A0A2V3JBX5.1
#=GS A0A0R2JYI2_9LACO/7-128 AC A0A0R2JYI2.1
#=GS A0A1S9CPW0_9FIRM/52-167 AC A0A1S9CPW0.1
#=GS A0A317TAX5_9CHLB/21-139 AC A0A317TAX5.1
#=GS A0A8J8GGG8_9BACI/21-132 AC A0A8J8GGG8.1
#=GS D3E3C1_METRM/20-140 AC D3E3C1.1
#=GS A0A212RQF8_9CHLR/19-140 AC A0A212RQF8.1
#=GS A0A2U3D8G5_9BACL/26-153 AC A0A2U3D8G5.1
#=GS A0A140L875_9FIRM/37-145 AC A0A140L875.1
#=GS A0LHY7_SYNFM/54-169 AC A0LHY7.1
#=GS L0DVX6_THIND/56-165 AC L0DVX6.1
#=GS A0A348AR48_9FIRM/46-155 AC A0A348AR48.1
#=GS A0A1I4LPK8_9PROT/38-154 AC A0A1I4LPK8.1
#=GS A0A1W1HIQ7_9DELT/16-133 AC A0A1W1HIQ7.1
#=GS A0A166ANN0_9EURY/139-251 AC A0A166ANN0.1
#=GS A0A654SG23_9CYAN/47-158 AC A0A654SG23.1
#=GS A0A1M4SM34_9THEO/32-137 AC A0A1M4SM34.1
#=GS I0I1X2_CALAS/16-138 AC I0I1X2.1
#=GS D4CPB6_9FIRM/33-155 AC D4CPB6.1
#=GS H6L656_SAPGL/12-155 AC H6L656.1
#=GS A0A0P6X793_9CHLR/16-143 AC A0A0P6X793.1
#=GS A0A8J7WB32_9EURY/16-132 AC A0A8J7WB32.1
#=GS A0A562R6V9_9DELT/13-132 AC A0A562R6V9.1
#=GS Q0AW51_SYNWW/34-157 AC Q0AW51.1
#=GS A0A5D8QAW1_9THEO/130-235 AC A0A5D8QAW1.1
#=GS E8LDK3_9FIRM/32-161 AC E8LDK3.1
#=GS A0A7L6AY40_9GAMM/10-136 AC A0A7L6AY40.1
#=GS A0A091C7A1_9ENTE/21-141 AC A0A091C7A1.1
#=GS A0A564ZGF2_9BACT/42-159 AC A0A564ZGF2.1
#=GS A0A1M7S1F1_9RHOB/20-131 AC A0A1M7S1F1.1
#=GS R5CZT8_9FIRM/7-131 AC R5CZT8.1
#=GS A0A3S1AFY1_CHLFR/27-116 AC A0A3S1AFY1.1
#=GS A0A563W3E1_9CYAN/59-180 AC A0A563W3E1.1
#=GS A0A267T0X7_9BACT/12-118 AC A0A267T0X7.1
#=GS D9S1M3_THEOJ/33-139 AC D9S1M3.1
#=GS A0A317CMW5_9GAMM/25-140 AC A0A317CMW5.1
#=GS A0A840U0M7_9BACT/32-138 AC A0A840U0M7.1
#=GS A0A0N0D745_9DELT/16-125 AC A0A0N0D745.1
#=GS G5GF96_9FIRM/8-140 AC G5GF96.1
#=GS A0A011N2Z7_9PROT/51-173 AC A0A011N2Z7.1
#=GS A0A091F8V1_9DELT/5-125 AC A0A091F8V1.1
#=GS A0A2K2FFM9_9FIRM/31-158 AC A0A2K2FFM9.1
#=GS A0A7W8DH89_9BACT/13-126 AC A0A7W8DH89.1
#=GS E4TFE7_CALNY/26-154 AC E4TFE7.1
#=GS A1BI34_CHLPD/37-154 AC A1BI34.1
#=GS A0A1M6DKE6_9FLAO/42-142 AC A0A1M6DKE6.1
#=GS A0A7U8TTD2_MYCTX/4-122 AC A0A7U8TTD2.1
#=GS G0VQ58_MEGEL/1-125 AC G0VQ58.1
#=GS A0A017H458_9FUSO/39-159 AC A0A017H458.1
#=GS A0A1I5TK12_9BACT/40-156 AC A0A1I5TK12.1
#=GS A0A1H7Z375_9FIRM/87-197 AC A0A1H7Z375.1
#=GS A0A0E3P1U4_9EURY/51-171 AC A0A0E3P1U4.1
#=GS A0A2N3IBP1_9BACT/46-147 AC A0A2N3IBP1.1
#=GS K1LC28_9FLAO/48-156 AC K1LC28.1
#=GS A0A379C9Q7_9PAST/11-128 AC A0A379C9Q7.1
#=GS Q8TPI0_METAC/51-165 AC Q8TPI0.1
#=GS R7NBV0_9FIRM/2-128 AC R7NBV0.1
#=GS A0A540VA63_9CHLR/16-142 AC A0A540VA63.1
#=GS C6HZN6_9BACT/23-141 AC C6HZN6.1
#=GS A0A0K1EQE5_CHOCO/96-199 AC A0A0K1EQE5.1
#=GS A0A143HPJ2_9GAMM/15-130 AC A0A143HPJ2.1
#=GS A0A2N4S8Y8_9BACT/98-207 AC A0A2N4S8Y8.1
#=GS A0A2H5W9R9_9BACT/30-140 AC A0A2H5W9R9.1
#=GS A0A1Z4SHU9_9NOSO/48-175 AC A0A1Z4SHU9.1
#=GS A0A0P1LL50_9BACT/18-132 AC A0A0P1LL50.1
#=GS B0VHA8_CLOAI/30-140 AC B0VHA8.1
#=GS R5DLY1_9FIRM/3-139 AC R5DLY1.1
#=GS A0A1H9GCF5_9GAMM/39-152 AC A0A1H9GCF5.1
#=GS A0A413QXC9_9FIRM/1-125 AC A0A413QXC9.1
#=GS R9NEX5_9FIRM/13-128 AC R9NEX5.1
#=GS A0A2H6AN01_9BACT/37-148 AC A0A2H6AN01.1
#=GS Q3AA77_CARHZ/36-142 AC Q3AA77.1
#=GS A0A0J6WPK5_9FIRM/1-129 AC A0A0J6WPK5.1
#=GS A9AZH0_HERA2/15-144 AC A9AZH0.1
#=GS A0A3Q9HQL7_9FIRM/34-143 AC A0A3Q9HQL7.1
#=GS A0A0C9NJJ0_9BACT/25-137 AC A0A0C9NJJ0.1
#=GS A0A4V3ESU3_9CLOT/37-145 AC A0A4V3ESU3.1
#=GS A8ZV92_DESOH/48-163 AC A8ZV92.1
#=GS A0A7W2ARW6_9BACL/16-127 AC A0A7W2ARW6.1
#=GS F6BES9_METIK/82-202 AC F6BES9.1
#=GS A0A212R0T4_9CHLR/33-148 AC A0A212R0T4.1
#=GS R5RKL5_9CLOT/3-124 AC R5RKL5.1
#=GS D5X8J0_THEPJ/1-125 AC D5X8J0.1
#=GS A1HM63_9FIRM/1-126 AC A1HM63.1
#=GS H1WB58_9CYAN/19-135 AC H1WB58.1
#=GS G9YKD0_9FIRM/1-141 AC G9YKD0.1
#=GS E6L000_9PAST/14-127 AC E6L000.1
#=GS A0A1I2C9D3_9BACT/46-147 AC A0A1I2C9D3.1
#=GS A0A1Y4UIH3_9FIRM/2-127 AC A0A1Y4UIH3.1
#=GS A0A1I4TBB1_9DELT/26-139 AC A0A1I4TBB1.1
#=GS A0A3M0BS85_9AQUI/37-145 AC A0A3M0BS85.1
#=GS Q82XX0_NITEU/12-128 AC Q82XX0.1
#=GS R7BLC9_9FIRM/13-130 AC R7BLC9.1
#=GS A9WEP9_CHLAA/31-148 AC A9WEP9.1
#=GS G8UKC5_TANFA/55-155 AC G8UKC5.1
#=GS O27153_METTH/27-139 AC O27153.1
#=GS C8PFL7_9PROT/33-140 AC C8PFL7.1
#=GS R9LQW8_9FIRM/43-158 AC R9LQW8.1
#=GS A0A381EEE3_9GAMM/16-142 AC A0A381EEE3.1
#=GS A0A2Z6IAW1_9BURK/26-141 AC A0A2Z6IAW1.1
#=GS U2ST39_9FIRM/9-137 AC U2ST39.1
#=GS A0A142XGT9_9BACT/24-137 AC A0A142XGT9.1
#=GS A0A5C8PUQ9_9HYPH/50-157 AC A0A5C8PUQ9.1
#=GS A0A2H5WP30_9BACT/27-143 AC A0A2H5WP30.1
#=GS A8USH3_9AQUI/87-191 AC A8USH3.1
#=GS A0A6A0BCF0_9LACT/6-128 AC A0A6A0BCF0.1
#=GS A0A3E2TGG6_9FIRM/5-135 AC A0A3E2TGG6.1
#=GS B5YH93_THEYD/39-149 AC B5YH93.1
#=GS A0A2H5X2C4_9BACT/11-138 AC A0A2H5X2C4.1
#=GS A0A8J2Z7G7_9PROT/67-179 AC A0A8J2Z7G7.1
#=GS Q1Q3H7_KUEST/31-142 AC Q1Q3H7.1
#=GS A0A4V1ERY1_9DELT/43-160 AC A0A4V1ERY1.1
#=GS F5YHB0_TREPZ/38-160 AC F5YHB0.1
#=GS D4S3J0_9FIRM/8-146 AC D4S3J0.1
#=GS A0A418MKP1_9BACL/41-151 AC A0A418MKP1.1
#=GS A0A2K9EEQ8_9FIRM/59-179 AC A0A2K9EEQ8.1
#=GS A0A6C1BR54_9AQUI/35-149 AC A0A6C1BR54.1
#=GS A0A1Q8ZG71_9CYAN/60-182 AC A0A1Q8ZG71.1
#=GS F9EMW7_FUSNU/4-119 AC F9EMW7.1
#=GS A0A1S9CEI6_9FIRM/46-161 AC A0A1S9CEI6.1
#=GS A0A396L2L6_9FIRM/13-128 AC A0A396L2L6.1
#=GS A0A1G5SGG9_9PROT/11-128 AC A0A1G5SGG9.1
#=GS A0A8J7FDV3_9CYAN/40-151 AC A0A8J7FDV3.1
#=GS A0A315XQY1_9EURY/25-134 AC A0A315XQY1.1
#=GS I3INX5_9BACT/54-167 AC I3INX5.1
#=GS A0A1M5TEK3_9FIRM/32-150 AC A0A1M5TEK3.1
#=GS A0A416HT99_9FIRM/12-128 AC A0A416HT99.1
#=GS A0A0P6WYP8_9CHLR/10-126 AC A0A0P6WYP8.1
#=GS B7C8S8_9FIRM/40-148 AC B7C8S8.1
#=GS K9Z4M5_CYAAP/58-176 AC K9Z4M5.1
#=GS A0A140DRJ8_9FIRM/45-159 AC A0A140DRJ8.1
#=GS A0A3P2AG10_9FIRM/6-129 AC A0A3P2AG10.1
#=GS A0A1G7LLN8_9DELT/13-130 AC A0A1G7LLN8.1
#=GS A0A2I5TBC8_SERS3/13-126 AC A0A2I5TBC8.1
#=GS J4TBU9_9FIRM/34-173 AC J4TBU9.1
#=GS L8LZ98_9CYAN/40-151 AC L8LZ98.1
#=GS A0A1E3X5U7_9BACT/11-129 AC A0A1E3X5U7.1
#=GS A0A1M5RL87_9FIRM/5-140 AC A0A1M5RL87.1
#=GS A0A5C7FKW1_9BACT/34-140 AC A0A5C7FKW1.1
#=GS M5J6B3_9LACO/5-137 AC M5J6B3.1
#=GS S0J6G0_9FIRM/26-137 AC S0J6G0.1
#=GS S0G409_9DELT/14-132 AC S0G409.1
#=GS A0A2H5XG79_9BACT/39-151 AC A0A2H5XG79.1
#=GS A0A7T6ARJ0_9DELT/16-132 AC A0A7T6ARJ0.1
#=GS Q5HK90_STAEQ/6-127 AC Q5HK90.1
#=GS A0A150AHN7_9BACT/16-135 AC A0A150AHN7.1
#=GS A0A1U7IFM3_9CYAN/19-146 AC A0A1U7IFM3.1
#=GS A0A1I0F327_9FIRM/32-142 AC A0A1I0F327.1
#=GS A0A1H3G5Z1_9PROT/37-150 AC A0A1H3G5Z1.1
#=GS A0A1I4S7F4_9DELT/19-133 AC A0A1I4S7F4.1
#=GS A0A166ANN0_9EURY/289-407 AC A0A166ANN0.1
#=GS A0A0D6XTM4_9STAP/17-136 AC A0A0D6XTM4.1
#=GS U5N6C6_9BURK/13-89 AC U5N6C6.1
#=GS A0A7Y2SS66_9CHLR/36-176 AC A0A7Y2SS66.1
#=GS A7HMV2_FERNB/40-153 AC A7HMV2.1
#=GS D5BXY5_NITHN/34-152 AC D5BXY5.1
#=GS G2SNW1_LIGR2/12-144 AC G2SNW1.1
#=GS A0A2H6ALA8_9BACT/43-166 AC A0A2H6ALA8.1
#=GS A0A1M6H8B6_9FIRM/54-178 AC A0A1M6H8B6.1
#=GS A0A1I2ENP4_9FIRM/44-168 AC A0A1I2ENP4.1
#=GS A0A1W1XZR9_9CLOT/28-134 AC A0A1W1XZR9.1
#=GS K8EGA5_9FIRM/64-177 AC K8EGA5.1
#=GS A0A077DE04_9BURK/12-129 AC A0A077DE04.1
#=GS A0A2A9HEZ5_CHLB2/43-149 AC A0A2A9HEZ5.1
#=GS A0A1Z4UQ24_9CYAN/49-160 AC A0A1Z4UQ24.1
#=GS A0A2H5ZAA1_9BACT/40-147 AC A0A2H5ZAA1.1
#=GS A0A0N8GL21_9CHLR/10-130 AC A0A0N8GL21.1
#=GS A0A1X3DFV8_9NEIS/24-137 AC A0A1X3DFV8.1
#=GS A0A844MUP9_9CYAN/79-190 AC A0A844MUP9.1
#=GS R6HG71_9FIRM/2-128 AC R6HG71.1
#=GS Q9X2D0_THEMA/10-130 AC Q9X2D0.1
#=GS A0A1T4NDP7_9ENTE/29-146 AC A0A1T4NDP7.1
#=GS C3WD51_FUSMR/39-154 AC C3WD51.1
#=GS A0A174CEU3_9FIRM/56-175 AC A0A174CEU3.1
#=GS A0A5B8Z4X5_BACDA/16-129 AC A0A5B8Z4X5.1
#=GS A0A1I0B6C0_9FIRM/4-130 AC A0A1I0B6C0.1
#=GS V8G871_9BURK/23-134 AC V8G871.1
#=GS L8MVT6_9CYAN/32-142 AC L8MVT6.1
#=GS A0A7K3Y040_9ACTN/79-194 AC A0A7K3Y040.1
#=GS A0A166FFM9_9EURY/25-142 AC A0A166FFM9.1
#=GS A0A0J9HKY5_9CYAN/23-151 AC A0A0J9HKY5.1
#=GS A0A1A8XHT3_9PROT/9-124 AC A0A1A8XHT3.1
#=GS A0A1Z4NIF6_9CYAN/20-131 AC A0A1Z4NIF6.1
#=GS A0A2N4S795_9BACT/39-140 AC A0A2N4S795.1
#=GS A0A2C6MIA9_9FIRM/46-154 AC A0A2C6MIA9.1
#=GS A0A0V7ZY67_9CYAN/18-129 AC A0A0V7ZY67.1
#=GS A0A080M2M7_9PROT/9-123 AC A0A080M2M7.1
#=GS A0A2M8RU54_9PAST/13-128 AC A0A2M8RU54.1
#=GS B5IHF3_ACIB4/40-147 AC B5IHF3.1
#=GS A0A3G9HL07_9PROT/9-131 AC A0A3G9HL07.1
#=GS F7YTM8_9THEM/41-145 AC F7YTM8.1
#=GS A0A011V386_RUMAL/25-151 AC A0A011V386.1
#=GS A0A218QHU9_9CYAN/27-125 AC A0A218QHU9.1
#=GS A0A844MUP9_9CYAN/27-87 AC A0A844MUP9.1
#=GS H1XX20_9BACT/15-128 AC H1XX20.1
#=GS F2NNA2_MARHT/3-133 AC F2NNA2.1
#=GS F6B7U1_DESCC/65-176 AC F6B7U1.1
#=GS A0A345UPN6_9BACT/30-146 AC A0A345UPN6.1
#=GS A0A4R2N139_9PAST/13-134 AC A0A4R2N139.1
#=GS A0A1G8JUM9_9LACT/3-116 AC A0A1G8JUM9.1
#=GS A0A0X1KU08_9THEM/33-150 AC A0A0X1KU08.1
#=GS A6UVY7_META3/49-166 AC A6UVY7.1
#=GS A0A3S1AFY1_CHLFR/78-190 AC A0A3S1AFY1.1
#=GS D7BB55_MEISD/13-130 AC D7BB55.1
#=GS G6EPC4_STRTR/4-125 AC G6EPC4.1
#=GS A0A250L0M0_9GAMM/43-164 AC A0A250L0M0.1
#=GS B8DZG6_DICTD/41-149 AC B8DZG6.1
#=GS A0A074LQ10_9BACL/50-163 AC A0A074LQ10.1
#=GS A0A1G5W0X7_9FIRM/1-137 AC A0A1G5W0X7.1
#=GS R6H6R0_9FIRM/32-150 AC R6H6R0.1
#=GS A0A846MQS3_9BACT/29-141 AC A0A846MQS3.1
#=GS A0A1Y6D309_9GAMM/15-127 AC A0A1Y6D309.1
#=GS CSM2_MYCTU/4-122 AC P9WJG1.1
#=GS A0A1V1P6B9_9DELT/11-117 AC A0A1V1P6B9.1
#=GS A0A3P1ZXR9_9DELT/9-122 AC A0A3P1ZXR9.1
#=GS A0A7U4QKA4_9DELT/45-156 AC A0A7U4QKA4.1
#=GS A0A2H5VXL5_9BACT/30-137 AC A0A2H5VXL5.1
#=GS A0A0B6WW76_9BACT/62-175 AC A0A0B6WW76.1
#=GS A0A2S9KB81_9BURK/49-164 AC A0A2S9KB81.1
#=GS A1ZV97_9BACT/18-146 AC A1ZV97.1
#=GS A3CN98_STRSV/54-174 AC A3CN98.1
#=GS F8E7K5_FLESM/17-138 AC F8E7K5.1
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A0A2H5WP30_9BACT/27-143 .............................dgg----KALVDLAERVG..RQV....KN....EG.................L.TTNQIRNIYGIVKQMEMRMKAPQQSD...................tGWNWYHELMMLKPKMAY...AAAR..............As...gRG..A.E..TLAKV.....LSVAI....D..E..VGSDR.................GKFPR....FVDLFEAILAYHKAAGG-k................
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A0A3E2TGG6_9FIRM/5-135 ......................netnyvdkae-KAIRSLRDKAEQQR..KGR....GE...lKI.................V.TTSKIRNLLAMTADIYNQVLRCQKDS...................lDEKLKGRMEYLRVRFMY...ECGRd...........dkD.....KL..V.T..NFVNEa...qILDVL....K..E..INGSK.................KNYIL....FSRYMEALIAFHKYYGGK.................
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A0A2H5X2C4_9BACT/11-138 .......sviaeignlqrmseldikkfaqedg---------LADRVV..QAI....GT....AS.................L.KPTQLRKVFHTLKGIQQKVKQQPDDP....................F--DSTDLLKLMPTLAY...AVGR..............E.....LI..P.K..EFYQL.....LREVFa..pS..R..LQTN-.................ADFLR....AFDFVEAILAYHKY----rs...............
A0A8J2Z7G7_9PROT/67-179 ............................aiea----GLLGTEAEQVA..QKL....--....AG.................V.PASQLRRFYAEVMALKRRVELAGASD....................-EEIRAHLTLLRAKAAY...TWGR..............Q....tQY..P.D..ELVLF.....FTRHA....A..S..VRTRH.................DFLRG....FQPHFEAVMAFHKVFER-k................
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D4S3J0_9FIRM/8-146 ...........................ltetd-----DIAGKAEKII..LGL....KN....DRllg..........gtngL.TTNQIRKFLTAVNTLTNKIILYRYQQmkargre......qekafemSDELAKAVRFLKVKLAY...QVAR.............gN.....KG..V.K..RFAEDt...rLKEYI....D..T..VGTDL.................REYMA....FAQFIEALVAYHKFYGE-k................
A0A418MKP1_9BACL/41-151 ..........................kwdatg------ILNVGEQLA..KVM....KD....KK.................V.TTSQIRKFIDELQRLRSSS-------....................-RLDLEQVKLTKIRLIY...AAGRae.........kgsA.....EA..L.K..NFEQA.....FSYAL....E..H..LHDK-.................QDFTN....LVRFVETVVAYHRYLGG-s................
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A0A6C1BR54_9AQUI/35-149 ......................drdifhpeeg---------YASKLV..RQL....--....-K.................L.TSVQLRRFYMEIRNIYEKYSQKQRDEk.................qeEAKLKYHLYKLYAMNSY...QLNRrv..........feD.....ES..F.S..ELVKA.....ILDCL....D..K..NFNK-.................ESLRK....ATDFFMAMIAYSK-----k................
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A0A416HT99_9FIRM/12-128 .............................aek--AILDLKGRKDKRG..RDI....--....KI.................V.TTSKIRNLLAMAADIYNEVINSQSEV...................lSEEIKGQINYMKIRFVY...ESGR..............E.....AT..V.K..NLVEQa...dILTHI....D..E..IGDSR.................EQYIL....FNRYMEALVAYRKFYV--eh...............
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A0A1M5RL87_9FIRM/5-140 ..............................aa--KSQDLIERARSIV..EDM....KG....NDgk.............laI.TTSQIRKFLAGVNRLENKYRIFKNDYisqhg.........rkpdklPAEMEQEIRFLEVKLIY...QVGRenn........nykK.....EK..L.K..QFYNH.....LAPDI....K..N..IGNNP.................EKFEE....FCRLMEAITAFHKYEGG-g................
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A0A7T6ARJ0_9DELT/16-132 ..............................lg------LLKMTEQLG..SEL....AKg.sgGK.................L.TTSQIRQVFTKLKAIEAKGFDLSEQR....................-----LAFMMLKPFLAY...ASGR..............Ds..rnEA..L.K..TFKNT.....MTWGI....D..A..VLEGDse............tetQRFNH....FCKLFEAVLAYHRAHGG-k................
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A0A1U7IFM3_9CYAN/19-146 ...............................d-YSIRTMVEQAEAFG..LEL....KR....QR.................L.ETNQVRKFLDALNQIKAKLPQVDEEVsnlkltf......eekekikFGKIESDIVLLKPKLAY...AAAR..............Q.....DA..V.K..SLNRV.....IAEAI....D..K..VHSK-.................ADFER....LVQLMESIIAYHKAAGG-k................
A0A1I0F327_9FIRM/32-142 ......................peklylpngk----------ACCFA..KQF....--....KY.................I.SNHQLRKILDSVKLAVRQCDND----....................FESARKQMFIIVAMSAY...NAGR..............D....pKK..L.T..ILYNF.....LESVIn..eN..T..IKTK-.................ADICA....FDQLFTSIVAYHKVAE--rr...............
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A0A3S1IB48_ANAVA/49-160 ...............................k-YPIRDLVNDAAKFG..PYL....KQ....QR.................L.ETNQIRKFLDAINRLKADLTEKGE--....................FSAIETEVVLLKPKLAY...AAAR..............Q.....RA..A.K..PLGDV.....MSSAI....D..Q..VHST-.................EDFER....LVQFIESIIAYHKAEGG-k................
G4D1Z0_9FIRM/3-118 ............................sklg------YVDEAEKII..KNL....SE...rKL.................L.NTNQIRKILSKVSVIYEKAKRKTGNL....................TEQEKMDLQVLRAHLIY...DSGR..............D.....EG..V.R..RFVSEa...kLVENI....K..E..IGDSR.................EKLLI....FCGYMEALVAYHKYY---lan..............
A0A0X8XBC2_HALHR/30-149 ..............................dd--QADQLVATAERLG..QDM....-G....KQ.................V.STSQVRNIFSSIKRLEMREQQHSPSGda................plSPNVRRELLLLKPRLAY...ATAR..............E.....NR..L.K..PLHDA.....VTTAL....D..V..VAQQGd...............qNALRR....LSAFYEAIVAYHQYHGG-k................
A0A2S3QEE7_9FIRM/23-130 ...........................yrrei------YREEAQFVV..DKL....AR....-G.................T.SIHALRRFYNRVKGLERSMDRGRL--....................FNQQKSQLYELQSHAYY...AAKR..............H.....LV..N.A..FFPTF.....MDRNV....D..Q..AVTNW.................EQFEG....FVKHFESVVAY-------fpte.............
A0A1R1MKU9_9BACT/25-140 ...............................e-KQAEVLKNKAEEIA..KLF....GS....DK.................T.SKHQIRKHFHRLLDIKERMKADDSDN....................IKKFLPEIAMTSAYATY...DRSR..............N.....RI..G.V..AFEKF.....LKEFT...nE..A..VKADK.................KKFFD....LMTLFEAIVGYSNMYV--sk...............
F8C647_THEGP/30-136 .......................yellkpngy----------AQQVV..K--....-E....NE.................L.TRVQLRKVFSEFKYVYDEYKKNKNKE....................--KAKIHLYKLYPLLQY...QVNR..............R.....LI..K.E..NFKNL.....IWAIL....D..T..LVGND.................EKFDEnlefSYEFLKALVAY-------i................
CSM2_METJA/22-132 ...............................s-QNANEIIDIAENLA..KEF....--....EQ.................I.PATKMRDFYDYVLRIDEKN-------....................-ENWYKELVLLKPKLAY...NYGKetn........rrkK.....EA..L.E..KLAGT.....FSEII....D..K..IDNDL.................NKFKN....FKTFFEALVAYHKIYAK-s................
A0A840UIR3_9FIRM/6-137 .............................lde---AKQFFDKAMEMR..KDR....PI....PA.................L.NTSKLRNFLNEVVTISNRVESLKAKRiqdnd..........dsndlPQDLQNLVDFLDVKLMY...QVGR..............EenkwpRP..L.K..KFYEAg...nMAERI....N..S..AKQGI.................REYKR....FADLMEAVVALHKYHGG-s................
K9QIE4_9NOSO/47-158 ...............................a-YEIRKLVKHAEEFG..PYL....KQ....QR.................L.ETNQIRKFLDAVTRLKADLSETGE--....................FAKIETEIVLLKPKLAY...AAAR..............Q.....RA..A.K..PLGEV.....MSAAI....D..K..VNSK-.................EDFER....LVQLIESIIAYHKAEGG-k................
A0A419T1F3_9FIRM/35-149 ....................pekyalpdgwaf------------KTA..NTL....IG...sNA.................M.NTNQIRKIFGELKSIEEKLKREKDL-....................-DKCKNDILLIMPQVAY...ALGR..............R.....VV..S.K..NFYDL.....MKECIn..lN..K..IKEP-.................EDFIA....FVKFFTAVVAYSSVV---ksk..............
A0A371ITI4_9FIRM/43-160 ............................klre----ELMLNETKEIA..KVF....VD....SK.................L.TSNQLRLFFNEVKALQNKIN-KDQQE....................FERNYPFILMLKSKAEY...KYKDg............kG.....TI..K.K..AFRDF.....INESV....D..Y..IKQHKs...............iNTFEN....FCMIFETIVGYYYGFGG-e................
M1E9I5_9FIRM/43-190 ..............................yk--SYDEFLKKAEEFA..ENL....AGd..gED.................L.GKSQLRKFYDDVINLRDEMINKLNNNkeekkdk......einvdeiINEIIFKLKLLQARVIY...LANRkktnk....ktyinS.....NA..R.K..YLLGI.....LERGI....T..L..CRQNEgdi..........kkiiSALKK....FSNEFEAIYAYFYQF---skd..............
#=GC seq_cons ..............................tt......h.p.Acphu..ppl....tp....pp.................l.pooQlR+hastlpplppchttttt.......................pchhsclthL+s+lAY...ssuR..............p.....ps..s.c..shhch.....lppsl....c..p..lpss..................csapp....FhpahEAllAY+Khht..p................
//
