#=GF ID   DUF1231
#=GF AC   PF06802.15
#=GF DE   Protein of unknown function (DUF1231)
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_9856 (release 10.0)
#=GF GA   25.00 25.00;
#=GF TC   25.60 25.20;
#=GF NC   21.00 20.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR009633;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several Orthopoxvirus specific proteins
#=GF CC   predominantly of around 340 residues in length. This family
#=GF CC   contains both B17 and B15 proteins, the function of which are
#=GF CC   unknown.
#=GF SQ   11
#=GS B17_VACCW/1-340           AC Q01221.1
#=GS A0A7J6LN45_PERCH/121-263  AC A0A7J6LN45.1
#=GS B17_VAR67/1-340           AC P0DOT1.1
#=GS Q775L3_CAMPS/1-136        AC Q775L3.1
#=GS Q0NP07_9POXV/1-340        AC Q0NP07.1
#=GS Q775L4_CAMPS/1-71         AC Q775L4.1
#=GS A0A223FN33_9POXV/1-334    AC A0A223FN33.1
#=GS Q0GNN5_HSPV/1-340         AC Q0GNN5.1
#=GS B17_VACCC/1-340           AC P21075.1
#=GS Q9JF36_VACCT/1-340        AC Q9JF36.1
#=GS A0A223FNN3_9POXV/1-334    AC A0A223FNN3.1
B17_VACCW/1-340                      ..............MSRKFMQVYEYDREQYLDEFIEDRYNDSFITSPEYYSAEKYMCRYTTLNHNCINV..RRCALDSKLLHDIITNCKI.YNNIELVRATKF...VYYLDLIKCNWVSKVGDSVLYPVIFITHTSTRNLDKVSVKTYKGVKVKKLNRCADHAIVINPFVKFKLTLPNKTSHAKVLVTFCKLKTDITPVEAPLPGNVLVYTFPDI.N.KRIP.GYIHLNIEGCIDGMIYINSSKFACVLKLHRSMYRIPPFPIDICSCCSQY.INY.DIEIPIHDLIKDVAIFKNKETVYYLKLNNKTIARFTYFNNIDTAITQEHEYVKIALGIVCKLMINNMHSIVGVNHSNTFVNCLLEDNV..
A0A7J6LN45_PERCH/121-263             lmypdiegkrvntf---------------------------EFVTSPHQSDPYMWMCDVAQLKNGDIMLlyQRYFAHRKFKVDVYYKVAIsYINIEAIREAVFkngIVTPTVIRLSWLAKDTWVTLWKVLHYTRTGTRYMYTSSARTMKGVSLSTLTIPNSTGLLIRPF----------------------------------------------.-.----.-------------------------------------------------.---.----------------------------------------------------------------------------------------y.
B17_VAR67/1-340                      ..............MSRKFMQVYEYDREQYLDEFIEDRYNDSFIASPEYYSAEKYMCRYTILNHNCVNV..RRCALDSKLLHDIITNCKI.YNNIELVRATKF...VYYLDLIKCNWVSKVGDSVLYPVIFITHTSTRNLDKVSVKTYKGVKVKKLNRCADHAIVINPFVKFKLTLPNKTSHAKVLVTFCKLRTDIMPIEAPYPGNVLVYTFPDI.H.KRIP.GYIHINIEGCIDGIIYINSSKFSCVLKLHRSMYRIPPFPIDICSCCSQY.TND.DIEIPIHDLIKDVVIFKNKEMVYYLKLNNKTIARFTYFNNIDTAITQEHKYVKIALGIVCKLMINNMHSIVGVNHSNTFVNCLLEDNV..
Q775L3_CAMPS/1-136                   ..............MSRKFMQVYEYDREQYLDEFIEDRYNDSFITSPEYYSAEKYMCRYTILNHNCVNI..RRCALDSKLLHDIITNCKI.YNNIELVRATKF...VYYLDLIKCNWVSKVGDSVLYPVIFITHTSTRNLDKVSVKTYKGVKVKK------------------------------------------------------------.-.----.-------------------------------------------------.---.----------------------------------------------------------------------------------------t.
Q0NP07_9POXV/1-340                   ..............MSRKFMQVYEYDREQYLDEFIEDRYNDSFITSPEYYSAEKYMCRYTILNHNCVNV..RRCALDSKLLHDIITNCKI.YNNIELVRATKF...VYYLDLIKCNWVSKVGDSVLYPVIFITHTSTRNLDKVSVKTYKGVKVKKLNRCADHAIVINPFVKFKLTLPNKTSHAKVLVTFCKLRTDIMPIEAPCPGNVLVYTFPDI.N.KRIP.GYIHVNIEGCIDGMIYINSSKFTCVLKLHRSMYRIPPFPIDICSCCSQY.TND.DIEILIHDLIKDVAIFKNKEMVYYLKLNNKTIARFTYFNNIDTAITQEHEYVKIALGIVCKLMINNMHSIVGVNHSNTFVNCLLEDNV..
Q775L4_CAMPS/1-71                    ..............-------------------------------------------------------..-------------------.------------...------------------------------------------------------------------------------------------MPIEAPCPGNVLVYTFPDI.N.KRIP.GYIHVNIEGCIDGMIYINSSKFTYVLKLHRSMYRIPPSPIDICSCCS--.---.----------------------------------------------------------------------------------------..
A0A223FN33_9POXV/1-334               .............m--KKFIHEYEYDRSKFLEEFVSD--NDGFIKS-----TEKDICIHATLKHNCNNV..RKYALDSSLMDDLLYDFKI.HNSIEIVRATKF...VYDIDLIRNNWISRNGDSILFPVIFIANTSSRNTDTVCIKTYKGIKIKKTSKSANFTVVINPSVNFKISLD-IASYAKVMITFCKLQTELPKEIKPKNGNVILYRFSNF.TeEEIPiGHMLIKINGCIDGNIYILSPKFMCGLRLQRSIYRYPLPPAETCSCCYPYsINDnEMEISIKELTKDIQILNT-NDRYYVYFGNLNVAKVTYFNSMDSKIQYDHYYIKVALGVFCKFMIKDINVIVGVNHNNTFLNCIVPD--tk
Q0GNN5_HSPV/1-340                    ..............MSRKFMQVYKYDREQYLDEFIEDRYNDSFITSPEYYSAEKYMCRYTTLNHNCVNV..RRCALDSKLLHDIITNCKI.YNNIKLVRATKF...VYYLDLIKCNWVSKVGDSVLYPVIFITHTSTRNLDKVSVKTYKGVKVKKLNRCADHAIVINPFVKFKLTLPNKTSHAKVLVTFCKLKTDITPVEAPLPGNVLVYTFPDI.N.KRIP.GYIHLNIEGCIDGMIYINSSKFACVLKLHRSMYRIPPFPIDICSCCSQY.INY.DIEIPINDLIKDVTIFKNKETVYYLKLNNKTIARFTYFNNIDTAITQEHEYVKIALGIVCKLMINNMHSIVGVNHSNTFVNCLLEDNV..
B17_VACCC/1-340                      ..............MSRKFMQVYEYDREQYLDEFIEDRYNDSFITSPEYYSAEKYMCRYTTLNHNCVNV..RRCALDSKLLHDIITNCKI.YNNIELVRATKF...VYYLDLIKCNWVSKVGDSVLYPVIFITHTSTRNLDKVSVKTYKGVKVKKLNRCADHAIVINPFVKFKLTLPNKTSHAKVLVTFCKLRTDITPVEAPLPGNVLVYTFPDI.N.KRIP.GYIHVNIEGCIDGMIYINSSKFACVLKLHRSMYRIPPFPIDICSCCSQY.TND.DIEIPIHDLIKDVAIFKNKETVYYLKLNNKTIARFTYFNNIDTAITQEHEYVKIALGIVCKLMINNMHSIVGVNHSNTFVNCLLEDNV..
Q9JF36_VACCT/1-340                   ..............MSRKFMQVYEYDREQYLDEFIEDRYNDSFITSPEYYSAEKYMCRYTTLNHNCVNV..RRCALDSKLLHDIITNCKI.YNNIELVRATKF...VYYLDLIKCNWVSKVGDSVLYPVIFITHTSTRNLDKVSVKTYKGVKVKKLNRCADHAIVINPFVKFKLTLPNKTSHAKVLVTFCKLRTDITQIEAPLSGNVLVYTFPNI.N.KRIP.GYIHVNIEGCIDGMIYINSSKFACVLKLHRSMYRIPPFPIDICSCCSQY.TNG.DIEIPIHDLIKDVAIFKNKETVYYLKLNNKTIARFTYFNNIDTAITQEHEYVKIALGIVCKLMINNMHSIVGVNHSNTFVNCLLEDNV..
A0A223FNN3_9POXV/1-334               .............m--KKFIHEYEYDRSKFLEEFVSD--NDGFIQS-----TEKDICTHATLKHNCNNV..RKYALDSLLMDDLLYDFKI.HNSIEIVRATKF...VYDIDLIRNNWISRNGDSILFPVIFIANTSSGNTDTVCIKTYRRIKIKKKSKSINFAAVINPSVNFKISLD-VASYAKVMITFCKLQTELPKEIKPKSNNVIIYRFSNFtE.EEIPiGYMLIKINGYIDRNIYIHSPKFICRLRLQRSIYRYHLPPAEICSCCYPYsINDnEMEISINELTKDIQVSKNNNY-HYVYFGNLNVAKVTYFNSIDYKMQYDKCYIKIALGVFCKFMIRDINVIVGVNHNNTFLNCIVPD--te
#=GC seq_cons                        ..............MSRKFMQVYEYDREQYLDEFIEDRYNDSFITSPEYYSAEKYMCRYTpLNHNClNV..RRCALDSKLLHDIITNCKI.YNNIELVRATKF...VYYLDLIKCNWVSKVGDSVLYPVIFITHTSTRNLDKVSVKTYKGVKVKKLs+sAsaAlVINPFVpFKloLs.hsSaAKVhlTFCKLpT-lh.lEAPhsGNVLVYTFPsI.s.KRIP.GYIHlNIEGCIDGhIYINSSKFsCVLKLHRSMYRIPP.PIDICSCCS.Y.hN..-hEIsIp-LhKDltIhKNpphhYYlhhsNhslA+hTYFNsIDotIp.-HpYlKIALGlhCKhMIpshpsIVGVNHsNTFlNCll.D....
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