#=GF ID   DUF1286
#=GF AC   PF06939.15
#=GF DE   Protein of unknown function (DUF1286)
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_15105 (release 10.0)
#=GF GA   25.00 25.00;
#=GF TC   25.50 38.10;
#=GF NC   24.70 24.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR009705;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several hypothetical archaeal proteins
#=GF CC   of around 120 residues in length. All members of this family
#=GF CC   seem to be Sulfolobus species specific. The function of this
#=GF CC   family is unknown.
#=GF SQ   32
#=GS A4YIT4_METS5/1-108       AC A4YIT4.1
#=GS A0A650CLA5_9CREN/1-114   AC A0A650CLA5.1
#=GS F4B5W2_ACIHW/1-80        AC F4B5W2.1
#=GS G4RNQ7_THETK/1-97        AC G4RNQ7.1
#=GS A0A4P2VCZ2_9ARCH/1-120   AC A0A4P2VCZ2.1
#=GS Q976C7_SULTO/1-112       AC Q976C7.1
#=GS A0A510DYH4_9CREN/1-126   AC A0A510DYH4.1
#=GS A0A830GSV2_9CREN/17-127  AC A0A830GSV2.1
#=GS A0A2U9IJ18_9CREN/1-108   AC A0A2U9IJ18.1
#=GS A0A348B2K0_9CREN/4-108   AC A0A348B2K0.1
#=GS A0A2T9WPK9_9CREN/1-104   AC A0A2T9WPK9.1
#=GS Q97X56_SACS2/1-126       AC Q97X56.1
#=GS Q4JC38_SULAC/1-112       AC Q4JC38.1
#=GS A0A0Q0VSG3_9ARCH/1-111   AC A0A0Q0VSG3.1
#=GS Q7LXI9_SACS2/42-151      AC Q7LXI9.1
#=GS Q6L2W9_PICTO/1-111       AC Q6L2W9.1
#=GS A0A510DZV2_9CREN/1-106   AC A0A510DZV2.1
#=GS A0A031LLB6_9CREN/1-105   AC A0A031LLB6.1
#=GS A0A348B2P1_9CREN/1-47    AC A0A348B2P1.1
#=GS A0A830GTR7_9CREN/1-99    AC A0A830GTR7.1
#=GS A4YGV9_METS5/1-100       AC A4YGV9.1
#=GS Q971Q5_SULTO/1-112       AC Q971Q5.1
#=GS Q97WT8_SACS2/4-128       AC Q97WT8.1
#=GS A8MAZ4_CALMQ/1-111       AC A8MAZ4.1
#=GS Q684G6_9VIRU/2-112       AC Q684G6.1
#=GS Q96ZI4_SULTO/1-112       AC Q96ZI4.1
#=GS A0A2R4ZME9_9CREN/1-105   AC A0A2R4ZME9.1
#=GS H2C7Q7_9CREN/1-100       AC H2C7Q7.1
#=GS W7KKS2_9CREN/1-112       AC W7KKS2.1
#=GS A0A4P2VLT4_9ARCH/1-120   AC A0A4P2VLT4.1
#=GS A0A0N9P4Z0_9VIRU/1-110   AC A0A0N9P4Z0.1
#=GS F4B666_ACIHW/16-123      AC F4B666.1
A4YIT4_METS5/1-108                  ....MRLVTHYVFTMGLLSLIMSMFTP.....---YYLVLSGVVAIAGNLIIDGLGHKEVQTRRGiTIPTRTPLTHTYPRSVVWGFLPVI.PFLA--..FGF...........MYGDF..PWWLLLA...GVLVGPSHMFL.
A0A650CLA5_9CREN/1-114              ....MKLQTHYVFSLGLLTFLDTLLVH.....HFYTSLFFSGVVSVLGNTLIDRLGHE-VRSVYGkEIIKRTPLTHTLPRSVIWGFIPAL.LLSLLY..YYIy.........eYVSEE..LLSLALV...SLLNGPSHMLL.
F4B5W2_ACIHW/1-80                   .mkd-----------------------.....--------SGIISVTANNVIDYLGHE----IRG.KYVSRTPRTHTLPRSIGWGLLTSV.PIVLAL..YFL...........SPTEL..ILITILD...GVIVGPSHMLL.
G4RNQ7_THETK/1-97                   ....MKLATHAVFTAGTLALILRAVGV.....EPWRALWEAWAVSILANVVIDFLGHRG------.--RRRSPLTHTPLRSLAWGALSSA.PAVYLA..H--...........-----..SYLPLLA...GALAGPLHLAL.
A0A4P2VCZ2_9ARCH/1-120              ....MKLATHYAFTIGLVALAARTFLP.....-VAGAIAAAAWLGLLVNWIIDRAGHE----VRG.GIPRRTAGTHSLPGAVGVGVAVGV.LPVALM..ALVdptal.aaagiQLSGV..PLIALIMaalGALAGLSHLLL.
Q976C7_SULTO/1-112                  ....MKLKTHYVFSLGVISLVLVFLSN.....NFFVSFFVAAYSSILGNSLIDKIGHRELLTGRG.YIPVRSPLTHTYPRSVLWGLLPTI.PLIFLI..HYM...........YGYYA..LIEVLVS...GVIVGPTHMFL.
A0A510DYH4_9CREN/1-126              ....MKLRTHYIFSTGLLSLLDSVLFH....eYFYYTLILSGIVSVIGNFLIDRIGHKEIVTRYG.YIPVRTPLTHTIPRSVIWGIVSIV.PVLILLliYYYgfsyheyyfslLNNKV..ILLTLLN...GLVVGPSHMLL.
A0A830GSV2_9CREN/17-127             ....LKLLTHYVFSTGLLALAATSMGA.....AFPSALFISLITSVMGNSIIDGLGHE----ERG.GYVRRTPLTHTVPRSIAWGAVPGI.IISLLL..AYGs........qwRVTPL..AVIVLLS...NLLLGPSHMFL.
A0A2U9IJ18_9CREN/1-108              ....MRLRAHYIFSSGLLSLITVFFIP.....-FLYAVFLAGLISFIGNSFIDYFGHE----IKG.KYISRTPRTHTVYRSILWGLLLSL.PIGVFL..YFV..........fPSFLF..VFSVILD...GLLVGPSHMIL.
A0A348B2K0_9CREN/4-108              ....MRLSTHYVFTTGMLSILG--WGT.....NFYYGLILASLISLSSNTIIDRLGHE----VRG.GYVRRTPRTHTLGRSILWGLIPSF.FIFLF-..LFL...........VSGGL..LFQILSM...GIVAGPSHLLL.
A0A2T9WPK9_9CREN/1-104              ....MKLVTHYVFSTGLLALLSSFFLN.....-FYTAFFLSSIIAVLGNSLIDRLGHKEIQTRRG.LIPVRTPLTHTLPRSVLWGWIPSL.ILIPL-..---...........--HGG..II-ISLI...ALLNGPSHMLL.
Q97X56_SACS2/1-126                  ....MRLRTHYVFSTGLLTLLDSGIFH....eYFYYTLILCGIVSVIGNSLIDRIGHKEIITRYG.YISMRTPLTHTIPRSVVWGIISII.PIFILLliYYYglnyheyylfsINNRV..ILLTLLN...GIVVGPSHMLL.
Q4JC38_SULAC/1-112                  ....MRLYAHYVFTIGVLVFINSFLVTplsppNYYDSLFYGGLLSVFSNTLIDRLGHE----IRG.KYISRTPTTHTFPRSMLWSLLVSV.LLSFL-..FFY...........VRHTI..PYYLLID...GVIAGPSHMVL.
A0A0Q0VSG3_9ARCH/1-111              ....MKLMVHYIFSTGILSLINSYFTG.....-FFRGFSIAVIMSFLGNTVIDHFGHKRKITKYG.LIPVRSPSTHSFENSIIIGLSISF.FIILIM..YIF...........NNLAP..ITITVIS...GILVGPSHLFL.
Q7LXI9_SACS2/42-151                 ....MKLKTHFVFSIGLLTLASSFFGF.....----SLIISAIISVLGNTLIDRLGHKEISTRYG.KIPVRTPLTHTLPRSVFWGLISSM.PVIIVLglAYG...........MLNTK..ILTALID...GILVGPSHMLL.
Q6L2W9_PICTO/1-111                  ....MKLTSHYVFTAGILTFINAHFMP.....-FFRAFSLSVIISFISNFIIDSLGHSHSKNN--.KINARTPLTHTFERSMAWGSFSSF.IIMALAilNSN...........INKQF..LIMCIVS...GIISGPSHMLL.
A0A510DZV2_9CREN/1-106              ....MRLATHYVFTTGVLALFFSYFTS.....---YYLVLAGVLAVAGNLIIDGLGHKEIHTRRG.TIPTRTPLTHTVPRSVVWGMLPSI.PFFAL-..-GL...........LVGDF..PWFLLLS...-MAIGPSHMLL.
A0A031LLB6_9CREN/1-105              ....MKLRTHYVFSTGLLTLFTYFLYP.....ALI-TPIVAGLISIIGNLTIDKLGHE----IRG.KYISRTPRTHTLPRSIGWGILLSL.PFVITL..FFL...........--NFN..FIIGIID...GFLVGPSHMLL.
A0A348B2P1_9CREN/1-47               ...m-----------------------.....---------------------------------.---RRTPRTHTLPRSVLWGLLPSL.PFLFL-..---...........FRDPL..PL---AL...GLLVGPSHMFL.
A0A830GTR7_9CREN/1-99               ....MLLKVHVIFTMGLCALVASSLDS.....--EAIIGIAIIQSIIVNYAIDQLGHR------G.--GVRIPRTHSPTGALITG-LSTA.PLALLA..--K...........VTPIY..VTAVALI...GALAGLSHLLL.
A4YGV9_METS5/1-100                  ....MKLVSHYVFTAGLLTLISSPFLS.....-FYTSLVLSFLISWVSNTLIDRLGHE----IRG.GYIRRTPRTHTLFRSIPWGLIPAI.PLALF-..---...........---EG..YPILLVL...GVLAGPSHLLL.
Q971Q5_SULTO/1-112                  ....MKLRTHYVFSLGVISLVLAFLSN.....NFFLSFFIAAYSSILGNSLIDRLGHRELLTGRG.YIPVRSPLTHTYPRSVLWGLLPTI.PLIFLI..HYM...........YGYYA..LIEVLVS...GVIVGPTHMFL.
Q97WT8_SACS2/4-128                  ...v-RLRTHYIFSTGLLTLLDSVLFH....eYFYYALILSGIVSVIGNSLIDRIGHKEIATRYG.YIPVRTPLTHTIPRSVVWGIVSVV.PVFILLliYYYgfsyh.eyyfsLSNKV..VLLILLN...GVVVGPSHLFL.
A8MAZ4_CALMQ/1-111                  ....MRFRTHVVFSIGLTALIESALGI....sNIILLLGSSLVLSYLINFLIDALGHEEKN----.GFTHRSPRTHTMSRSFTLGLIISL.LVALFL..YYMt.........pIGAYN..ALIIVLM...GPLTGWSHMLL.
Q684G6_9VIRU/2-112                  medk----LHATLATGMLTLLNATFIG.....-MPDALFLGAITAIMANVLIDGFGTERIDEN--.-NYYTTPETHTIPHATLLGVVTGL.VSAILI..NMLt........glAFLSI..IPLALMG...GVIAALLHLA-l
Q96ZI4_SULTO/1-112                  ....MKLRTHYVFSLGVISLVLVFLSN.....NFFVSFFVAAYSSILGNSLIDKIGHRELLTGRG.YIPVRSPLTHTYPRSVLWGLLPTI.PLIFLI..HYM...........YGYYA..LIEVLVS...GVIVGPTHMFL.
A0A2R4ZME9_9CREN/1-105              ....MRLFSHIVAGIGAGS-IASMLYG.....NHYGAFLYIVILSFVINIIID-LGHTRIR----.GIVIRSPYTHEVLNSMAISILIGS.IVWIA-..VGN...........LYGVS..LYASLLA...SLLISGSHLL-g
H2C7Q7_9CREN/1-100                  ....MKLLTHYIFTTGFLTLLSTPYLG.....-FYVSLLLSSVISSLSNTLIDRLGHE----VRG.GFVRRTPTTHTLPRSVIWGLLPSL.PLFYFF..---...........----H..VLPILLL...GVLSGPSHMLL.
W7KKS2_9CREN/1-112                  ....-------MFTLGLLLLADSFLLR.....NFILSLSLSLIVSILANSLIDGLGHRELHTPKG.DIITRTPLTHTFPRSVVWGVISSL.PLVASI..YYFntl....qyepSAFKL..IALSLVD...GAIAGPSHLVL.
A0A4P2VLT4_9ARCH/1-120              ....MKLTTHYLFTIGLVALIACPILP.....-LSGALVVAIWLGVATNWIVDMVGHED----RD.GAARRTAATHSLPGAAGVGLVLGVlPVALVA..LFAptal..iaagvQLSEV..PFIALLMgalGILAGLSHLLL.
A0A0N9P4Z0_9VIRU/1-110              ....MQLRTHYIFSFGLLTLLNFILLS.....GSPLLVVNAGVLSIFINNVIDTLGHE----IKG.EYISRTPTTHTIPRSIGWGLLGSV.PFALAL..HFV...........FHSPImlILITFMD...GAVAGLSHMLL.
F4B666_ACIHW/16-123                 ....MKLRTHYVFSLGLLSLLDSFLLS.....NFLEVIIISGIISVTANNVIDYLGHE----IRG.KYISRTPRTHTLPRSIGWGLLTSV.PIVLAL..YFL...........SSTEL..ILITILD...GVIVGPSHMLL.
#=GC seq_cons                       ....M+LtTHYlFohGlLoLlsshhhs......hhhulhluullSlluNslIDtLGHc....hhG.thstRTPhTHTlPRSlhWGllsol.Plhhlh..hhh...........h.t.h..lhhsLls...GllsGPSHMlL.
//