#=GF ID   DUF1495
#=GF AC   PF07381.15
#=GF DE   Winged helix DNA-binding domain (DUF1495)
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_20509 (release 10.0)
#=GF GA   22.00 22.00;
#=GF TC   22.00 22.10;
#=GF NC   21.90 21.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0123
#=GF DR   INTERPRO; IPR010863;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This family consists of several hypothetical archaeal proteins
#=GF CC   of around 110 residues in length. The structure of this domain
#=GF CC   possesses a winged helix DNA-binding domain suggesting these
#=GF CC   proteins are bacterial transcription factors.
#=GF SQ   30
#=GS M7TFF9_9ARCH/1-49        AC M7TFF9.1
#=GS A0A2V3JF11_9EURY/22-110  AC A0A2V3JF11.1
#=GS Q0W4R7_METAR/13-103      AC Q0W4R7.1
#=GS Q5JEC4_THEKO/10-98       AC Q5JEC4.1
#=GS A0A2V3JDA6_9EURY/26-113  AC A0A2V3JDA6.1
#=GS Q0W464_METAR/10-99       AC Q0W464.1
#=GS Q0W5R0_METAR/19-105      AC Q0W5R0.1
#=GS Q0W280_METAR/55-145      AC Q0W280.1
#=GS F0LGX0_THEBM/1-43        AC F0LGX0.1
#=GS Q8U3W1_PYRFU/9-97        AC Q8U3W1.1
#=GS Q9HJ88_THEAC/14-102      AC Q9HJ88.1
#=GS T0MVJ3_9ARCH/9-101       AC T0MVJ3.1
#=GS L0KZ10_METHD/18-106      AC L0KZ10.1
#=GS Q0W465_METAR/11-99       AC Q0W465.1
#=GS A0A0F7DBA2_9EURY/14-102  AC A0A0F7DBA2.1
#=GS M7T7U6_9ARCH/18-107      AC M7T7U6.1
#=GS Q0W609_METAR/1-71        AC Q0W609.1
#=GS A0A1Q6DXH5_9EURY/16-104  AC A0A1Q6DXH5.1
#=GS M7T8Z4_9ARCH/18-109      AC M7T8Z4.1
#=GS T0NC19_9ARCH/9-98        AC T0NC19.1
#=GS D3RYQ2_FERPA/14-102      AC D3RYQ2.1
#=GS A0A2R6T7P6_9ARCH/13-97   AC A0A2R6T7P6.1
#=GS A0A2R6T8Q6_9ARCH/17-105  AC A0A2R6T8Q6.1
#=GS Y905_METJA/10-98         AC Q58315.1
#=GS A0A218ZTA8_9ARCH/9-96    AC A0A218ZTA8.1
#=GS Q0W601_METAR/8-95        AC Q0W601.1
#=GS Q6LWJ1_METMP/13-101      AC Q6LWJ1.1
#=GS A0A8J8P6D1_9EURY/8-85    AC A0A8J8P6D1.1
#=GS C6A2K4_THESM/7-95        AC C6A2K4.1
#=GS Q0W4L2_METAR/14-106      AC Q0W4L2.1
M7TFF9_9ARCH/1-49                   ........................................m------------------------------------------IGAL.R.GM.N.SRYKKEESLISLDVIEEKSG..GKNIR..LYG.......ITPFGKEMMET-v..........
A0A2V3JF11_9EURY/22-110             .........................................ILRSLRRSRVRTEIVMYLYKIYPRASYPAEISRNTGIDPTNVLGGL.R.GM.G.NRFDAESSLLTQGIVE-KVE..HKKAT..YYR.......LSKLGKALIES-m..........
Q0W4R7_METAR/13-103                 .........................................IMYAMRKSVVRMKILVYLF-VCGEPRNIQQITNVVGTWPSHVRGAM.W.GM.G.KRYNAESSLLARGLVARLSGdiNSNVT..TYT.......LTEKGRAYVL--li.........
Q5JEC4_THEKO/10-98                  .........................................VLRSLHRSELRKRILMYLNEIYPSATYLSEIARVIGSDPSNVRGAL.V.GL.G.NRYNNESSLVYLGLV-EEIS..RNGFK..YYR.......LTEYGKRVVDYL...........
A0A2V3JDA6_9EURY/26-113             ........................................a-LRSLRRSRVRSEILMYLYKNYPEALYPAEIARNTGIDLQVVLRGL.K.GT.G.-RFDTSNSLLQQGLVE-AIE..RGNET..CYR.......LSERGKSLIEH-t..........
Q0W464_METAR/10-99                  .........................................VMSAIIKSMVRFKVLVFLASHPREEFDAPNMAHRIRSASENVTGAL.E.GY.E.KRYSKALSLVSLGLVTYREK..EPGTR..VYK.......ITPEGIAFAEKV...........
Q0W5R0_METAR/19-105                 .........................................IYHSMIRSQARRKILLDLKRNGP--GNTTDLSTRTGYHYSNTRGAL.V.GN.G.EKYDSELSLVTTGLANA---..DPGTKeiIYS.......LTPTGEEVANI-v..........
Q0W280_METAR/55-145                 ................................idmideskk--------TTKRKVLELLDS-TSRPKDDAEIIAAVAIDEKELRQII.K.AI.NnEHYTYEESLLGMGLVKEWKR..LFREP..GFT.......ITDKGRYV----llyi.......
F0LGX0_THEBM/1-43                   ........................................m----------------------------------------------.-.GL.G.NRYNGHSSLVSLGLV-EIIE..ENGFK..YYR.......LSEYGKRVVEML...........
Q8U3W1_PYRFU/9-97                   .........................................ILRSLHRSELRRRILHYLYEIYPSATYLSEIARVVSSDPSNVRGAL.V.GL.G.NRYNSESSLVYLGLV-EEIV..NNGFK..YYR.......LTEYGKKVVEML...........
Q9HJ88_THEAC/14-102                 .........................................ILRSLNRSELRRKVLFYLLSIYPYRSYLSEISRAVKSDPSNVKGCL.E.GL.G.VRYTGEESLIGLGLVIVEQS..KNGFK..YFK.......INPE--------iveevrn....
T0MVJ3_9ARCH/9-101                  .........................................IIRSLNRSELRRKVLFYLYSIYPYRSYLSEISRAIKSDPSNVKGCL.E.GL.G.IRYTKEESLVGLGLVTIEES..KKGFR..YFK.......INKD--------ciddikgiktv
L0KZ10_METHD/18-106                 ........................................l-IRSLMRSEVRKSILLYLYDIYPLSSYPAEIARRVNANPINVIGAI.K.GV.K.TRYNCSSSLLHLGII-SVIE..DNGLK..FYQ.......ISETGIELAKHL...........
Q0W465_METAR/11-99                  .........................................-IRSVHECKSRDIVLDFLHANMENAYHPIAIIKSTALKRPHVIGAL.E.GG.A.GGMESRCSLVSQGMVSRELS..SQGPA..RYR.......ITPPGIAIVEFL...........
A0A0F7DBA2_9EURY/14-102             .........................................ILRSINKSVLRRKVLFYLYNIYPNYDYLANISRMIRSDPSNVLGCI.R.GM.G.NRYNGSSSLIELGLV-EVVE..KEGFK..YYR.......ITDLGRKVVEYV...........
M7T7U6_9ARCH/18-107                 ........................................a-IRALRRSNVRKRIAEYLFDISPSYSYTSDIAYHIRTTPSNVIGAM.R.GM.Q.TRYKEEESLINLDMVEEKNC..GNNIR..LYG.......ITDFGKEMLK--ti.........
Q0W609_METAR/1-71                   .....................................mkav----------------------GKTTTMYDASKLTKLGYTNIKLAV.I.GD.D.RKYKRMYSLVNTGLV-CCEE..VEDRC..YLT.......LTDKGARAAL--vl.........
A0A1Q6DXH5_9EURY/16-104             .........................................VIRSLNKSSLREKILLFLNDVEPKYAYLSEIARSVRSDPSNVSGCL.E.GM.K.KRYSERLSLVEMGLV-EVIE..KDRHS..YYG.......ITEKGQKAAEY-i..........
M7T8Z4_9ARCH/18-109                 .........................................VIRSLRRSNVRKKIADYLFDISPSGSYTSEIAYNVKTTPTNVIGAI.R.GM.N.SRYRGDESLISLNLVEQFNSgkKNDIK..LYK.......LTDFGKEIVESL...........
T0NC19_9ARCH/9-98                   .........................................IIRSLNRSELRRKVLFYLLSIHPYRSYLSEISRAVKSDPSNVKGCL.E.GL.G.VRYTGEESLVGLGLVSFEQS..KNGFK..YYK.......INTD--------fiedvkal...
D3RYQ2_FERPA/14-102                 .........................................ILRSINKSVLRKKVLFYLYSIYPNYDYLANISRRVRSDPTNVLGCL.K.GM.G.NRYNGSSSLIELGLV-EVVE..KDGYK..YYR.......ITDLGRKVVEYV...........
A0A2R6T7P6_9ARCH/13-97              .........................................VIKSIHRSRVREKTLLFLDDIFPKSSYLSQIGREIKSDPSNVKGCL.E.GM.G.ERYKAERSLIELGLVEEV--..---DE..RYR.......VSERGRDIAEK-i..........
A0A2R6T8Q6_9ARCH/17-105             .........................................ILRSIKKSRLREEILLFLFDIKPQYSYLSEIARNVRSDPSNVLGCI.K.GM.S.KRYSESRSLMELNLV-GVVE..KDGKS..YYG.......ITDKGVSVAKY-i..........
Y905_METJA/10-98                    .........................................IIRSLNKSKLRKKILYLLYKMYPHGIYLSEISRRVRSDPSNVLGCL.K.GM.N.GRYNGHFSLIELGLV-ECVE..RGGVK..IYK.......LTDYGKKIVEVL...........
A0A218ZTA8_9ARCH/9-96               .........................................VIRSLNRSELRRKALFYLLSIYPYRSYLSEISRAIKSDPSNVKGCL.E.GL.G.VRYTVEESLVGLALVKVEQT..KNGFK..YFK.......INP---------dvvdevr....
Q0W601_METAR/8-95                   .........................................IVASIGRSSVRKKILLYLY--HSTASTMYDIARDTRTAYTNATGAI.A.GF.G.KRYGKERSLIHLGLVRMEKG..NRGLN..VYS.......LTPEGRRLADVL...........
Q6LWJ1_METMP/13-101                 .........................................IIRSLNKSKLRKKIVYFLYDIHPHGTYLSELSRRVKSDPSNVLGCL.K.GM.G.NRYNGSSSLIELGLV-NCDG..KEGMK..IYQ.......MTTYGKTVVEYL...........
A0A8J8P6D1_9EURY/8-85               ......................................vsy----VISSSYRVKVLQRLA---DSPATPSRIATDTDRPTTHVSRAL.Q.GL.R.-----DHDLVEL-LVS--EE..RQKGR..VYG.......ITEEGESIWET-i..........
C6A2K4_THESM/7-95                   .........................................ILRSLHRSELRKKILFYLHEIYPSPTYLSEIARIVRSDPSNVKGAL.V.GM.G.NRYNGDSSLVHLGLV-EEIT..QNGFK..YYK.......LTEHGEKVVGF-l..........
Q0W4L2_METAR/14-106                 .........................................IYSALNSSRVRQDVYEYLCSIYPRKAFIQELSKETRHSVTNLKGSL.E.GD.G.ISFSYDDALIELGLAE----..SAEIR..LYRkiaksfgATEQGFRIRDRL...........
#=GC seq_cons                       .........................................llRSlp+SplRcKlLhaLhplhPptsYhu-IuRtl+ocPoNVhGsL.c.Gh.G.pRYss-pSLlpLGLV.ph.p..csGh+..hY+.......lT-hGcpls-h............
//