#=GF ID   DUF1678
#=GF AC   PF07913.15
#=GF DE   Protein of unknown function (DUF1678)
#=GF AU   Fenech M;0000-0001-7933-4617
#=GF SE   Pfam-B_4886 (release 14.0)
#=GF GA   25.00 25.00;
#=GF TC   25.50 25.40;
#=GF NC   23.60 22.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR012465;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family is composed of uncharacterized proteins expressed by
#=GF CC   Methanopyrus kandleri, a hyperthermophilic archaebacterium. 
#=GF SQ   17
#=GS Q8TYJ9_METKA/5-200     AC Q8TYJ9.1
#=GS Q8TVU7_METKA/7-202     AC Q8TVU7.1
#=GS Q8TXS6_METKA/17-240    AC Q8TXS6.1
#=GS Q8TYH4_METKA/4-121     AC Q8TYH4.1
#=GS A0A5C6CW69_9BACT/2-88  AC A0A5C6CW69.1
#=GS Q8TWA0_METKA/10-205    AC Q8TWA0.1
#=GS Q8TVS9_METKA/7-202     AC Q8TVS9.1
#=GS Q8TVV1_METKA/1-188     AC Q8TVV1.1
#=GS Q8TXL5_METKA/21-227    AC Q8TXL5.1
#=GS Q8TW73_METKA/7-202     AC Q8TW73.1
#=GS Q8TVP5_METKA/5-200     AC Q8TVP5.1
#=GS Q8TW79_METKA/5-200     AC Q8TW79.1
#=GS Q8TVY6_METKA/7-194     AC Q8TVY6.1
#=GS Q8TYG8_METKA/5-200     AC Q8TYG8.1
#=GS Q8TVW9_METKA/1-149     AC Q8TVW9.1
#=GS Q8TWT7_METKA/7-202     AC Q8TWT7.1
#=GS Q8TUW7_METKA/5-200     AC Q8TUW7.1
Q8TYJ9_METKA/5-200                .....HVP..IPSDPVERIRALRVLREVHRRKRKPSLEVTYRTVSGSTCGPYYVARWRRDSKFKHGRTLYLGKPENESVRFV.EWL.........VSLDRNEVLELARHLMRNLRSVLKTL...........LTGVSDLPYKRARRVLARGLALTFDA.RPSESPR.....IRDVLEELPDRLESFAIRTLGGWPAHYSAHLRKVIRHRRKSLDGKHEIPDVKLELERWK......................
Q8TVU7_METKA/7-202                .....HIP..IPSDPVERIRVLRVLREVHRRGRKPSLEVTYRTVNGSTCGPYYVARWRRGSRHRHGRTLYLGKPENESVSFV.EWL.........VSLDKKQVLELARHLMRNLRSVLKTL...........LTEVSSLPYKRARRVLTRGLALTFDA.RPSESPR.....IRDLLEELPDRLESFTVRTLGGWPAHYSSYLRKVIRSRRKSLNGRHEVPDVQLELERWK......................
Q8TXS6_METKA/17-240               ....g-VPmeVPEDPVELVRVFRVLVETLERGTLPFLGASYRSVNGKVYGPYYEARWK-PRKGERGRTIYLGREDNESVQFLrEWLetirlaaprLSEHRKAKWFVARAVRRALVPVLRQLaqmsaehraevLQKLEEIVKEGVSRTCSILRSVEFNPlRRLGWPGsgkeiIDSVLRGLPGTVRDILVDVLAPWPAWYSLRIVRLWRGEREARRYWRERVGLYDRVKQRE......................
Q8TYH4_METKA/4-121                ..tss---..------------------------------------------------------------------------.---.........--PGREEVLELARQLMRNLRSVLKTL...........LTEVSDLPYKKARRLLARGLALTFDA.RPSESPR.....IRDLLEELPNRLEPFLVRTLEGWPAHYSAHLKRIIR-RRKSLDGKHETPGVKLELERWK......................
A0A5C6CW69_9BACT/2-88             stttg---..-------------------------LVQMSYRQVRGETYGPYMSFRYR---ENGKQRSYYIGSSLSEQILAL.EIMh......ekLEADRER------HYM----------...........--------------------------.-------.....-----------------------------------------------------------dslltkarqqlresktkwnkns
Q8TWA0_METKA/10-205               .....HVP..IPSDPVERIRALRVLREVYRRGKKPSLEVTYRTVGGSTCGPYYVARWRKDSRFKHGRTLYLDKSENESVSFV.EWL.........VSLDRSEVLELARHLMRNLRSVLKTL...........LTEVLSLPYKKARRVLTRGLALAFDA.RPSNSPR.....IRDLLEELPDRLESFAVRTLGGWPAHYSSYLRKVIRSRRRSLDGRHEVPDVELELERWK......................
Q8TVS9_METKA/7-202                .....HVP..IPSDPVERIRALRVLREVYRRGKKPGFEVTYRTVSGSTCGPYYVARWRRDSKFRHGRTLYLGKPENESVRFT.EWL.........VSLDRSEVLELARHLMRNLRSVLKTL...........LTEVSSLPYKRARCVLTRGLALAFDA.RPSNSPR.....IRDLLEELPDRLESFLVRTLGGWPAHYSSHLNKIIRSRRKSLDGRHEVPDVQLELERW-r.....................
Q8TVV1_METKA/1-188                ....m---..------ERIRALRVLREVYRRGKKPGLEVTYRTVSGNTCGPYYVARWRRDSRFKHGRTLYLGKPENGSVRFV.EWL.........VSLDREEVLELARHLMRNLRSVLKTL...........LTEVSGLPYKQARRVLARGLALAFDA.RPSESPR.....IRDVLEELPDRLESFTVRTLGGWPAHYSSHLKRVIRSRRRSLDGKHEVPDVGLELQRWK......................
Q8TXL5_METKA/21-227               ....r-VP.ePPRDPVEQARVLRVLLETVRRGVLPFLGASYRSVNGKVYGPYYEARWK-PRKGERGRTIYLGKSENESVRFLeAWLwevrraaprLAEHRKAKWFVARAVRRALAALLARFe........gdPEEALELAGEVLRKVGGILTGMPFDPlRTYSRPRggrklLRMLLGRTPGEFRDVLLEMLSPWPPWYCLTLLERLHGRTAAREYHRARV----------pr....................
Q8TW73_METKA/7-202                .....HVP..IPSDPVERIRALRVLREVYSRGKRPSLEVTYRTVNGSTCGPYYVARWRRDSRHKCGRTLYLGKPENESVRFV.EWL.........VSLNRAEVLELARHLMRNLRSVLKTL...........LTEVSSLPYKQARRVLARGLALTFNA.RPSNSPQ.....IRDLLEELPDRLESFAVRTLGGWPAHYSAHLNKIIRFRKRSLDGKHEVPDVMLELERWK......................
Q8TVP5_METKA/5-200                .....RIP..IPSDPVERIRALRVLREVYRRGKKPSLEVTYRTVNGSTCGPYYVARWRCDSRFKHGRTLYLGKPENESVSFV.EWL.........VSLDRNEVLKLARHLMRNLRSVLKTL...........LTEISNLPYKRARRVLARGLALTFDA.RPSNSPR.....IRDVLEELPDRLESFLIRTLGGWPAHYSSHLNKIIRSRRKSLDGKHEIPDVLLELERWK......................
Q8TW79_METKA/5-200                .....HVP..IPHDPVERIRALRVLREVYRRRKKPSLEVTYRTVNGSTCGPYYVARWRRDSKFEHGRTLYLGKPENESVSFV.EWL.........VSLDREEVLELARHLMRNLRSVLKTL...........LTEVSDLPYKRARRVLARGLALTFDA.RPSDSPR.....IRDVLEKLPDRLESFLIRALGSWPAHYSSHLRKVIRSRRESLDGKHEIPDVEFELERWK......................
Q8TVY6_METKA/7-194                .....HIP..IPHDPVERIRTLRVLREVYRRGRKPSLEVTYRTVNGSTCGPYYVARWRRDSRFKHGRTLYLGKSENESVSFV.EWL.........VSLDRGEVLELARHLMRNLRSVLKTL...........LTEVSDLPYKKVRRVLARGLALAFDA.RPAGSPG.....IRDVLEELPDRLESFVIRTLGGWPAHYSSYLESSVRAGDSSTGGTR-------------yptws.................
Q8TYG8_METKA/5-200                .....HVP..IPHDPVERIRALRVLREVYRRGKKPSLEVTYRTVNGSTCGPYYVARWRRDSRHKRGRTLYLGKPENKSVRFV.EWL.........VSLDREEVLELARQLMRNLRSVLKTL...........LTEVSDLPYKKARRILARGLALAFDA.RPAGSPG.....IRDVLEKLPDRLESFLIRTLGGWPAHYSSYLGKVIHSRRKSLDGKHEIPDVKLELERWK......................
Q8TVW9_METKA/1-149                ....m---..--------------------------------------------AHWR-NSRHERGRTLYLGKSENESVSFI.EYL.........VSLNRAEVLELARHLMRNLRSVLKSL...........LPQVSSLPYKKARRVLARGLALAFDA.RPAESPR.....IRDLLEELPDRLESFFMRTLGGWPAYYFSHLRKVIRSRRGSLDEKHEIPDVKLE-----rwkfr.................
Q8TWT7_METKA/7-202                .....HVP..IPSDPVERIRALRVLREAYRRGKKPSLEVTYRTMGGSTCGPYYVARWRRDSRFKHGRTLYLGKPENESVRFV.EWL.........VSLDRGEVLELARHLMRNLRSVLKTL...........LAEVSDLPYKRARRVLARGLSLAFNA.RPSESPR.....IRDLLEELPDRLESFLIRTLGGWPAHYSIHLRKVIRSRKRSLDGRYEIPDVGLELEHW-r.....................
Q8TUW7_METKA/5-200                ....h-AP..IPYNPVERIRALRVLREVHRRRKKPSLEVTYRTVNGSTCGPYYVARWRRDPRHKHGRTLYLGKPENESVSFV.EWL.........VSLDRREVLELARHLMRNLRSVLKTL...........LTEVSDLPYKKARWVLARGLALAFDA.RPSESPR.....IRDLLEELPDRLESFAVRTLGGWPAHYSSYLRKVIHHRGKSLDEKHEVPDVGLEFQRWK......................
#=GC seq_cons                     ......lP..IPpDPVERIRsLRVLREVaRRG+KPuLEVTYRTVsGSTCGPYYVARWR+DS+a++GRTLYLGKsENESVpFV.EWL.........VSLDRpEVLELARHLMRNLRSVLKTL...........LTEVSsLPYK+ARRVLARGLALsFDA.RPSpSPR.....IRDlLEELPDRLESFhlRTLGGWPAHYSuaLpKlIRuRR+SLDG+HElPDVtLELcRWc......................
//