#=GF ID   DUF1999
#=GF AC   PF09390.14
#=GF DE   Protein of unknown function (DUF1999)
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF SE   pdb_2d4o
#=GF GA   25.00 25.00;
#=GF TC   25.60 25.60;
#=GF NC   24.50 24.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0257
#=GF DR   INTERPRO; IPR018987;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family contains a putative Fe-S binding reductase
#=GF CC   (Swiss:Q72J89) whose structure adopts an alpha and beta fold.
#=GF SQ   28
#=GS F0RM83_DEIPM/8-166       AC F0RM83.1
#=GS E8UBF9_DEIML/1-159       AC E8UBF9.1
#=GS F2NMB4_MARHT/12-160      AC F2NMB4.1
#=GS Q9RV36_DEIRA/4-163       AC Q9RV36.1
#=GS A0A318SLC6_9DEIO/1-158   AC A0A318SLC6.1
#=GS Q5SIW0_THET8/15-140      AC Q5SIW0.1
#=GS A0A399EUW8_9DEIN/1-149   AC A0A399EUW8.1
#=GS Q1IZG2_DEIGD/1-160       AC Q1IZG2.1
#=GS A0A072ND26_9DEIO/2-162   AC A0A072ND26.1
#=GS L0A302_DEIPD/1-159       AC L0A302.1
#=GS A0A1W1VGT5_9DEIO/1-160   AC A0A1W1VGT5.1
#=GS A0A418VAM8_9DEIO/1-159   AC A0A418VAM8.1
#=GS D7CU56_TRURR/6-147       AC D7CU56.1
#=GS A0A221SUJ4_9DEIO/2-161   AC A0A221SUJ4.1
#=GS A0A841I1M4_9DEIO/1-166   AC A0A841I1M4.1
#=GS A0A172T8F8_9DEIO/1-163   AC A0A172T8F8.1
#=GS A0A2K3UUH8_9DEIO/1-159   AC A0A2K3UUH8.1
#=GS A0A1U7NYK4_9DEIO/1-159   AC A0A1U7NYK4.1
#=GS A0A511N0E6_DEIC1/1-157   AC A0A511N0E6.1
#=GS A0A0X8D952_9DEIN/17-140  AC A0A0X8D952.1
#=GS A0A0F7JR72_9DEIO/1-159   AC A0A0F7JR72.1
#=GS A0A2Z3JGG9_9DEIO/1-159   AC A0A2Z3JGG9.1
#=GS A0A399FAC0_9DEIN/1-149   AC A0A399FAC0.1
#=GS D7BHQ5_MEISD/1-149       AC D7BHQ5.1
#=GS E4U4G5_OCEP5/1-150       AC E4U4G5.1
#=GS C1D1I5_DEIDV/2-161       AC C1D1I5.1
#=GS H8GTL1_DEIGI/2-164       AC H8GTL1.1
#=GS A0A7C9LS19_9DEIO/1-159   AC A0A7C9LS19.1
F0RM83_DEIPM/8-166                  ..............................................a-AYRLLLPDDYAALAELDLAAQHE.....L.....DPGFGG..LPEREREGRLS...TSLGALKFYERTDHSFVAV.RDGA..VAGMVLAQ...SV.W.QG.D.KPIVLVRTLLTDPA....LPEal..raEVYSGLLRALFKSAYDTAVYEV........HFVPHRRWPLA...ADLGDVRRLGD....YGVRYLGSREETA------lp..........................................................
E8UBF9_DEIML/1-159                  ...............................................MEYRTFHEPDFDALQALEARVLRA.....E.....DPNFDA..LAEREREGRVR...TSLAALKFFERSEHSFAAA.EGGT..LHGVILAQ...SV.W.QG.D.RPIVLVARALIAPD....APA......DTAAGLLRACVKSAYDAAVYEV........HFPLTDGLEDA...ARADGAYVTGQ....YAVRHLGTRAETAPGARL-g...........................................................
F2NMB4_MARHT/12-160                 ...............................................MEYRPFDEQDFPAMEAFERALLEG.....A.....PEHA--..---------YR...AHPAALRFFMRTGHSFVAS.TRDA..VHGFALAQ...AV.W.QG.D.RPTVFVTRILAADG....---......AAYEGLLRAVVKSAYDAGVYEVamh.idpeHEALVAAAQAA...GFTLGPLVL--....-ATRVLGSRGVRGETRHV-l...........................................................
Q9RV36_DEIRA/4-163                  ..............................................f-RYRQFSQPDFEVMQALDLAEQRR.....T.....APEYDV..LPEREQEARLS...SSLAALRHYERSGHSFVAEgQDDH..VRGYVLAQ...SV.W.QG.D.RPAVFVRALVLDDA....QDE......DMRRGLLRAVVKSAYDAAVYEV........HLPVTPELHAA...ARAEEAHLTGQ....YAVIHLGTRAESAPGKKLR............................................................
A0A318SLC6_9DEIO/1-158              ...............................................MMYRAFTSADFDALRALDLAVQRR.....E.....DLAFDT..LSEREREGRLR...TSEAALRFFERSEHSFVAD.DDGE..LRGAIFAQ...SV.W.QG.D.RPIVLIVRLWTAQG....APE......DTARGLLKVCSKSAYDAAVYEV........HGPVPADLVDA...AREEGFVRIGA....YGVRHMGTRRETAPGEA--l...........................................................
Q5SIW0_THET8/15-140                 ..........................................nrlag------------------------.....-.....------..--------KRP...VSLGALRFFARTGHSFLAE.EGEE..PMGFALAQ...AV.W.QG.E.ATTVLVTRIEGRSV....---......EALRGLLRAVVKSAYDAGVYEValh.ldpeRKELEEALKAE...GFALGPLVL--....-AVRVLGSRGARGETRGV-l...........................................................
A0A399EUW8_9DEIN/1-149              ...............................................MICRDIQESDFEALGALERELLGQ.....Q.....PTH---..--------RYR...CTPGALRFFSRSGHSFVAV.EADE..IVGVALAQ...AV.W.QG.D.QVTVLITRLLSRSD....---......AAIRALLGAVVKSAYDAGVYEVamh.vdpnNPAMCQALQDH...GFQLGPLVL--....-GVRVLGSRGERGEVAGV-l...........................................................
Q1IZG2_DEIGD/1-160                  ...............................................MRYRSFAEPDYEALQALDLAAQRR.....A.....DPAFDA..LPDRERAGRLS...TSLPALKFYERSEHSFVAQdEAGQ..LQGLILAQ...HV.W.QG.D.RPIVLVRAVILAPD....APE......DTAAGLLRATVKSAYDSAVYEV........HFPLLPALEAA...ARREEARLTGG....YAVCHLGTRAATAPGERL-g...........................................................
A0A072ND26_9DEIO/2-162              ...............................................LRYRTFNEADFEALRQLDLAAQHA.....A.....DPGFDA..LPERERAGRLS...TSHAALKFYERSEHSFVAQ.GEGMtgLAGAIFAQ...HV.W.QG.D.RPIVLVRTVLLSPG....APE......QTAAGLLHAVVKSAYDSAVYEV........HFPVTPALEGA...AEQEEAHLVGG....YGVCHLGTRAATAPGTRL-g...........................................................
L0A302_DEIPD/1-159                  ...............................................MLYRAFTPADFGPLVDLDLTVLRR.....E.....DPLFDT..LSEREREGRVR...TSLAALRFYERSEHSFVAE.EDGE..LRGAIFAQ...SV.W.QG.D.RPTVLVTRLWLARP....ADA......DVTSGLLRACSKSAYDAAIYEL........HLGVTAELQEG...AAREHFREQGV....YAVRLLGSRADSAPGREMK............................................................
A0A1W1VGT5_9DEIO/1-160              ...............................................MRYRTFSEADYPALQALDLAAQRH.....L.....DPAFDT..LPQREREGRLS...TSLPALKFYERSEHSFVAGdEAGE..VQGAVLAQ...HV.W.QG.D.RPIVLVRTVLLSPE....AGP......SVASGLLHATVKSAYDTAVYEV........HFALIPQLVAA...AGEEGAHVTGQ....YAVRHLGTRADTAPGQRV-g...........................................................
A0A418VAM8_9DEIO/1-159              ...............................................MEFRFFGEPDYAALQALDGLVQRA.....Q.....EPGFEA..LPEREREGRLS...TSPASLKFYERSEHSFVAD.AGAG..LQGFILAQ...SV.W.QG.D.RPIVLVRTVVVHPD....APE......SVRQGLLHATVKSAYDTAVYEV........HVPASEQLLPA...AQQEEAHLQGQ....YAVIHLGTRAGSAPGVKL-s...........................................................
D7CU56_TRURR/6-147                  .................farplspedealteldrryaeafgleplls------------------------.....-.....------..-----------...--RSSVLFYVRTGHAFVAV.RAGE..ATGFVLAQ...AV.W.NG.A.RPTVYVNRLAVPDP....EDT......ASREALLEAVTKSAYDAGVYDL........WVQVPEADAAA...AAALGAKRYRAlperLYARTLGSRGQR-------............................................................
A0A221SUJ4_9DEIO/2-161              ..............................................q-SYRSFTERDYGVMQALDLAAQRH.....A.....DPEFDT..RPDREREGRLN...TSLPALKFYERSEHSFLAEdEQGV..AQGFVLAQ...PV.W.QG.D.RPIVLVRTVTLAPG....APE......ATAPGLLHAAVKSAYDTAVYEV........HYPLTPALLPA...AEAEGSNVIGR....YAVQHLGTRNETAPGEQL-g...........................................................
A0A841I1M4_9DEIO/1-166              ...............................................MLYRVFNENDYDDLRALDLEVLRF.....E.....TPGFDA..LPEREREGRTR...TSLAALRFFERSEHSFVAE.QDGL..LAGAIFAQ...SV.W.QG.D.RPIVLVSRLWVRPG...lQDQdpavalEVARGLLKVCSKSAYDAAIYEL........HLAVPDELQAA...AALEEFRTPGR....YAVRYLGSRSETAPGSRL-s...........................................................
A0A172T8F8_9DEIO/1-163              ...............................................MRYRVPTEHDYDALHALDLAALRH.....A.....DPAFDT..LPDREREGRIC...TTLPALKFYERSEHSFVAE.DDGV..LHGFIFAQ...SV.W.QG.D.RPVVLVRTVALAPHaqpdAQA......ATAEGLLHATVKSAYDTAVYEV........HFAVTPALEAA...AVAEGAHVLGR....YAVRHLGTRADTAPGQKL-g...........................................................
A0A2K3UUH8_9DEIO/1-159              ...............................................MRYRTFGEADYAALQALDLRLQRA.....A.....DPAYDT..LPEREREGRLH...TSPAALKFYERSEHSFVAD.QGGT..LQGFVLAQ...AV.W.QG.D.RPTVLIRTLSQTPD....APA......GTPEGLFQAVIKSAYDTAVYEV........HFPVSPALHAV...AQAEGTRVLGA....YGVCHLGSRTQTAPGSRL-g...........................................................
A0A1U7NYK4_9DEIO/1-159              ...............................................MRYRIFTEQDNDALQALDLTVQRH.....L.....DPTFDA..LPEREREGRIS...TSLPALKFYERSEHSFVAE.DEGQ..LVGFIFAQ...SV.W.QG.D.KPIVLVRTLSLSPG....APV......ETAQGLLHATIKSAYDTAVYEV........HFPLVPGLEDT...ARAEEAVTIGA....YAVRHLGSRLETSPGVRL-n...........................................................
A0A511N0E6_DEIC1/1-157              ...............................................MRYRAFTEIDHDAIVALERIVLLQ.....E.....EPTFDS..LPEKEKEGRIR...TTEASLRFFQRTEHSFVAE.FDDV..IHGAVLAQ...SV.W.HG.D.KPTVWISRIMIHPD....APE......GTLTGLLKACSKSAYDTAIYEL........HTCLTPDQ--V...ADAEGFRSQGI....YAVRHLGSRSETAPGDKL-a...........................................................
A0A0X8D952_9DEIN/17-140             ..........................................lagkr------------------------.....-.....------..----------P...VSLGALRFFARTGHSFLAE.EGEE..PMGFALAQ...AV.W.QG.E.ATTVLVTRIEGRSV....---......EALRGLLRAVVKSAYDAGVYEValh.ldpeRKELEEALKAE...GFALGPLVL--....-AVRVLGSRGARGETRGV-l...........................................................
A0A0F7JR72_9DEIO/1-159              ...............................................MRYRTFAEHDYDALQALDLVVQRA.....H.....TPAFDT..LAERERAGRLH...TSLPALKFYERSEHSFVAE.EDGT..LHGFIFAQ...SV.W.QG.D.RPIVLVRALSVHPD....APA......GVSEALLHATVKSAYDTAVYEV........HYPVTPELRAA...AAAESAVLTGA....YAITHLGTRAQTAPGERL-d...........................................................
A0A2Z3JGG9_9DEIO/1-159              ...............................................MRYRTFSEADFAALAALDLDVQRR.....A.....DPAFDT..LEAREQEGRLR...TSLGALKFFERSEHSFLAE.DERG..VQGLILAQ...PV.W.QG.D.RPIVLVVQTLLSAG....AGP......EAAAGLLHACIKSAYDTAVYEV........HFPLTPELEAA...AEVEAAHVVGR....YAVRHLGSRLQTAPGQQL-g...........................................................
A0A399FAC0_9DEIN/1-149              ...............................................MTYRDFEEFDFPALARLEQRLLEG.....Q.....PPHL--..---------YR...ATPAALRFFSRSGHSFLAH.FAGE..VHGFVLAQ...TV.W.QG.D.RVTVLITRLLADSD....---......EAYRGLLAAVVKSAYDAGVYEValh.vdagDAPVVRALSEN...GFTLGPLLL--....-AVRVLGSRGMRGETTGV-l...........................................................
D7BHQ5_MEISD/1-149                  ...............................................MVFRDFAEPDFARLEAYEKAKLGE.....Q.....PPHV--..---------YR...CTPAGLRFFSRSGHSFMAL.EEER..IVGFALAQ...AL.W.QG.D.QVTVLLTRILADAQ....---......EVYQGLLGAVVKSAYDAGVYEValh.ldpaHTELKSALEAH...SFVLGPKIL--....-AVRVLGSRGQRQEVQGV-l...........................................................
E4U4G5_OCEP5/1-150                  ...............................................MHFRFLEEPDFAELQALERRIFPG.....R.....PEAF--..---------YR...TAPAALRYYARSGHSFAAV.DGER..LLGFVLAQ...AV.W.QG.D.RATVLVTRIAAESA....---......EVYAGLLRALIKSAYDANAYEVallaepgdRPELDRALADA...QLADSGRRL--....-HTRVLGGRGARGETGGV-l...........................................................
C1D1I5_DEIDV/2-161                  ...............................................MLYRTFGEADHAALQALDLRVQRH.....T.....DPSFDS..LPEREREGRLH...TSLPALKFYERSEHSFVAQdPQGT..LQGFVFAQ...PV.W.QG.D.RPVVLMRTLTLSPD....APA......GTAAGLMHAVVKSAYDTAVYEL........HYPLTPALLDA...AQQEGANVIGQ....YAVQHLGSRNGTAPGQQLR............................................................
H8GTL1_DEIGI/2-164                  ...............................................LRFRTLTEHDYDALAALDLAAQRA.....L.....DPAFDT..LPDRERESRLS...TSLPALKFYERSEHSFVAD.GEGG..LRGFVFAQ...SV.W.QG.D.RPLVFVRTLALAPG...lTPEl...vdEAARGLLHAVVKSAYDTAVYEI........HLPLTAELANA...ARAEEARVVGQ....YGVVHLGTRAQTAPGERLR............................................................
A0A7C9LS19_9DEIO/1-159              ...............................................MRYRTFGEQDYVSLQALDLLAQRT.....A.....DPAFDT..LPAREQEGRLH...TSLPALKFYERSEHSFVAE.EDGQ..LHGVVLAQ...SV.W.QG.D.RPTVLVRTLTTRPG....AAP......EVAASLLHATVKSAYDAAVYEV........HFALTPDLAGA...ALQEEAVVTGC....YAVCHLGTRAQTAPGVRL-g...........................................................
#=GC seq_cons                       ...............................................MpYRsFsEtDasALpALDLts.Rt.....t.....-PsFDs..Ls-RE+EGRlp...TSLuAL+FYERSEHSFVAc.csGp..lpGhlLAQ...uV.W.QG.D.RPhVLVpplhlsss....sst......pstpGLL+AsVKSAYDsAVYEV........HhslsssLpsA...AtsEuspllGt....YAVRHLGoRupTAPGppl.h...........................................................
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