#=GF ID   DUF2099
#=GF AC   PF09872.13
#=GF DE   Uncharacterized protein conserved in archaea (DUF2099)
#=GF AU   COGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   COGs (COG4022)
#=GF GA   25.00 25.00;
#=GF TC   25.10 56.90;
#=GF NC   21.90 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR009181;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This domain, found in various hypothetical prokaryotic proteins,
#=GF CC   has no known function.
#=GF SQ   97
#=GS Q2NHI9_METST/6-259        AC Q2NHI9.1
#=GS A0A062V3T7_9EURY/3-256    AC A0A062V3T7.1
#=GS A0A2V2N9X0_9EURY/5-258    AC A0A2V2N9X0.1
#=GS A0A8J8B410_9EURY/8-261    AC A0A8J8B410.1
#=GS A0A1Q6DVL6_9EURY/6-256    AC A0A1Q6DVL6.1
#=GS Q12YZ2_METBU/3-256        AC Q12YZ2.1
#=GS A0A328PD41_9EURY/4-253    AC A0A328PD41.1
#=GS A7IA71_METB6/10-263       AC A7IA71.1
#=GS L0HFE9_METFS/10-263       AC L0HFE9.1
#=GS H1YXT1_9EURY/5-258        AC H1YXT1.1
#=GS Q0W683_METAR/4-258        AC Q0W683.1
#=GS Q6LWR3_METMP/6-261        AC Q6LWR3.1
#=GS A0A0W7THI4_9ARCH/8-257    AC A0A0W7THI4.1
#=GS G7WK31_METH6/3-254        AC G7WK31.1
#=GS G7WLT5_METH6/4-265        AC G7WLT5.1
#=GS A0A0E3NYX9_9EURY/3-256    AC A0A0E3NYX9.1
#=GS O27615_METTH/7-257        AC O27615.1
#=GS A0A2V2NBU7_9EURY/1-70     AC A0A2V2NBU7.1
#=GS F4BY84_METSG/4-260        AC F4BY84.1
#=GS D3E0P1_METRM/4-260        AC D3E0P1.1
#=GS L0HF58_METFS/8-261        AC L0HF58.1
#=GS B1L4C3_KORCO/2-254        AC B1L4C3.1
#=GS R9T570_METII/1-249        AC R9T570.1
#=GS A0A2U1S605_9EURY/4-258    AC A0A2U1S605.1
#=GS A0A1D2W565_9EURY/4-258    AC A0A1D2W565.1
#=GS A2SQB6_METLZ/5-260        AC A2SQB6.1
#=GS Q8PT56_METMA/3-256        AC Q8PT56.1
#=GS D7DUV9_METV3/7-279        AC D7DUV9.1
#=GS A0A0Q4BE22_9ARCH/4-254    AC A0A0Q4BE22.1
#=GS F4BTJ3_METSG/2-255        AC F4BTJ3.1
#=GS A0A498H709_9EURY/7-260    AC A0A498H709.1
#=GS A0A2V3JIK1_9EURY/1-231    AC A0A2V3JIK1.1
#=GS A0A1D3L1T6_9EURY/4-258    AC A0A1D3L1T6.1
#=GS E1RD37_METP4/8-261        AC E1RD37.1
#=GS R9SLQ3_9EURY/6-259        AC R9SLQ3.1
#=GS A0A110A2X6_THEX5/1-250    AC A0A110A2X6.1
#=GS A0A8J7Y9Q3_9EURY/4-99     AC A0A8J7Y9Q3.1
#=GS A0A2Z4L777_9EURY/6-259    AC A0A2Z4L777.1
#=GS Q8TYZ1_METKA/6-259        AC Q8TYZ1.1
#=GS D7E9Y3_METEZ/3-256        AC D7E9Y3.1
#=GS A0B9J8_METTP/2-254        AC A0B9J8.1
#=GS Q8TUM7_METAC/11-265       AC Q8TUM7.1
#=GS F7XM64_METZD/3-256        AC F7XM64.1
#=GS A0A328SIC9_9EURY/154-231  AC A0A328SIC9.1
#=GS D1YXD5_METPS/4-257        AC D1YXD5.1
#=GS Q8TNR3_METAC/3-257        AC Q8TNR3.1
#=GS A0A2V2N2E7_9EURY/7-192    AC A0A2V2N2E7.1
#=GS A0A1V6N4Y2_METAZ/4-262    AC A0A1V6N4Y2.1
#=GS M4YU01_THEXX/5-256        AC M4YU01.1
#=GS A0A315XP45_9EURY/6-261    AC A0A315XP45.1
#=GS A7I529_METB6/9-262        AC A7I529.1
#=GS D1YVK2_METPS/7-261        AC D1YVK2.1
#=GS A0A1F2P745_9EURY/4-263    AC A0A1F2P745.1
#=GS A0A1F2P8Y1_9EURY/10-266   AC A0A1F2P8Y1.1
#=GS W9DRC6_METTI/3-256        AC W9DRC6.1
#=GS F4BW83_METSG/4-260        AC F4BW83.1
#=GS A0A2V3JFY8_9EURY/9-258    AC A0A2V3JFY8.1
#=GS A0A483CNS0_9EURY/5-258    AC A0A483CNS0.1
#=GS E3GYC0_METFV/5-253        AC E3GYC0.1
#=GS B8GFH3_METPE/8-261        AC B8GFH3.1
#=GS A0A062V0M5_9EURY/8-263    AC A0A062V0M5.1
#=GS A6UTW8_META3/5-277        AC A6UTW8.1
#=GS M9SBN7_METAX/10-260       AC M9SBN7.1
#=GS A0A0X3BKZ5_9EURY/1-67     AC A0A0X3BKZ5.1
#=GS A0A8J8C8Y6_9EURY/1-209    AC A0A8J8C8Y6.1
#=GS A0A1Y3GEN4_9EURY/6-255    AC A0A1Y3GEN4.1
#=GS A0A6B9TBV7_9ARCH/4-255    AC A0A6B9TBV7.1
#=GS A0A396QG24_9FIRM/105-381  AC A0A396QG24.1
#=GS A0A1F2P597_9EURY/11-267   AC A0A1F2P597.1
#=GS A0A166CH84_9EURY/4-258    AC A0A166CH84.1
#=GS A0A328SIC9_9EURY/6-157    AC A0A328SIC9.1
#=GS D5EBB8_METMS/3-256        AC D5EBB8.1
#=GS A0A0Q4B9C2_9ARCH/4-254    AC A0A0Q4B9C2.1
#=GS I7KZB0_METBM/7-260        AC I7KZB0.1
#=GS U6E9T3_9EURY/4-258        AC U6E9T3.1
#=GS Q0W8U3_METAR/4-258        AC Q0W8U3.1
#=GS A0A0X3BLF2_9EURY/7-186    AC A0A0X3BLF2.1
#=GS Y054_METJA/4-257          AC Q60361.1
#=GS A0A2V3JR45_9EURY/3-256    AC A0A2V3JR45.1
#=GS E1RJI0_METP4/6-261        AC E1RJI0.1
#=GS A0A8J7UQW8_9EURY/4-257    AC A0A8J7UQW8.1
#=GS F6BBW8_METIK/5-259        AC F6BBW8.1
#=GS A0A165ZJG0_9EURY/4-258    AC A0A165ZJG0.1
#=GS F0T748_METLA/4-258        AC F0T748.1
#=GS A0A062V1M8_9EURY/6-263    AC A0A062V1M8.1
#=GS A0A4E0PXD3_9EURY/3-256    AC A0A4E0PXD3.1
#=GS A0A0A7LD54_9ARCH/5-255    AC A0A0A7LD54.1
#=GS A0A0E3NWD7_9EURY/3-257    AC A0A0E3NWD7.1
#=GS A0A328S6R4_9EURY/6-259    AC A0A328S6R4.1
#=GS Q8PT59_METMA/3-257        AC Q8PT59.1
#=GS A0A484F367_9EURY/3-264    AC A0A484F367.1
#=GS Q2FU23_METHJ/4-257        AC Q2FU23.1
#=GS L0KZ42_METHD/3-256        AC L0KZ42.1
#=GS A0B8M2_METTP/4-260        AC A0B8M2.1
#=GS A0A162FM61_9EURY/7-261    AC A0A162FM61.1
#=GS A0A1D3L1X7_9EURY/14-268   AC A0A1D3L1X7.1
#=GS Q8TNP5_METAC/3-256        AC Q8TNP5.1
Q2NHI9_METST/6-259                   ...................................................................HVIEALGKT..RVTIENG..KVSNVE..KPLIEYCPIFAK.YRNI.EEITPELVRENIQF.RIDDFGMCTKNRQIKMS.-DMLSVGISEILRSNLEVGNIDCVVGACEGVGTLLMTDADIVQGVGGRASGLVSTTPIPE..VMEK..IGIEN--VLDAQTAQLNPIKGLEKAINEGYKNIAITILP..SPLI..KKIREYDL................PSDVNVYLFVAHTTGI.SMDETKDVF.KYADIVTSCASKNIRDYASKI......KPYYYGSSVPIYAVSDMGRKFLDTRL-e...
A0A062V3T7_9EURY/3-256               ...................................................................HIMELFGKT..RVVIENG..KIIEVG..EPVADWCPVFSK.VASV.SRLTKEEAKKNMEY.RIKELGMFTPNRRFDHG.-VFVNFGASEIMMTALRRGLIDTTVTVCDGAGTVITSNPDLVQGMGALMSGLIETEPIPE..IIEG..IELRGGTVLDRESAGIDQAGGLRKACELGYERIAVSVVG..TDDA..GELRAIEK................EHNIDLILIGAHLTGI.QHAKAEGFI.KEMDIVTGCASKIVRHMVK--......PVLQVGTSVPMFAMTQMGKELLCERAK....
A0A2V2N9X0_9EURY/5-258               ...................................................................HIIEAIGRS..RIVVRDG..KVVEVG..EAVITDCPLAKRfACPV.EEFTPEAVKKNIEN.RIEAFGMCTPERSLISD.DDFVGFGASELTRTGLASGIIDAAVLACDGAGTVVVTDPAMAQGIGGRMSGLVSTSPIRS..VIER..IEAGGGIVPDPVYASIDPLAGIAAAHKAGYSRLLVTVAG..ADAA..EAVRNADP................----SAIIMAVHVTGT.SREDAVRIS.EVADISTGCASRHIREVCGKK......ALMQAGTVVPIFILTRRGKELLLARL-a...
A0A8J8B410_9EURY/8-261               ...................................................................HIIEAIGRA..RIVVRDG..EVIEVG..EPMIRDCPLAKRfAYPI.PEMSREHIAENIRH.RIRAFGMCTPDRQVEDD.REFVGFGASEIISFGMKAGILDAAVLACDGAGTVIVTKPSMVQGIGGRMSGLVRTVPYRS..VIER..IEEGGGIVLDQNGATMDQVEGAARAVAEGFAHIAVTVAL..PGDA..ETIRGLFP................----DILIIGVHVTGL.SEAEAEMLV.SASDIVTACASGSIRRIAGER......ALLQAGVSVPVFAMTKRGKELLIEKI-r...
A0A1Q6DVL6_9EURY/6-256               ...................................................................HVLELLGRT..KVILRDG..KIESID..EPIIDFCPLMKK.MKGV.DSIK-GMAEKQIET.CKREFGFCTPNREFNEK.-DVVDFGISETLKVALEEDMLDAAVIVCEGSGTVITSNPGLVQGIGGRLSGIVEISPIKK..IIEK..IKEKNGYVLEPP--RISQIDGYKKAKKMGFDRIAVTISS..KKDI..KRFRGFKD................--DEDLTLIGVHLTGL.DNEKIERLV.SMVDIATACASKKIRELSKEK......ANLQAGSSIPVYSYTQRGRDLILERAK....
Q12YZ2_METBU/3-256                   ...................................................................HVMEILGKT..KVVVENG..KVVEVG..EPEIDWCPLFEK.ARGI.KKITREAVKENMEF.RIKDFGLFTKDRMLEMD.-VFVGFGASEVMMTGLGRDILDTTVTVCDGAGTVITNNPVLVQGMGARISGLVETEPIDE..VIDR..IEKMGGIVLEPSKAIIDPIGGVLKAIELGFKRIAVTVVD..PETA..RILREIES................ENNLEMMIIGAHTTGL.SREDALEIV.KYLDIIASCASKAIRDIIK--......PLAQVGTAVPLFALTQKGKELLLERAK....
A0A328PD41_9EURY/4-253               ...................................................................HIIEALGRA..KIIIKDG..RIVSLG..EPMIKYCPLFHK.YRGI.KELNKETIRENIEF.RIRDFGMCTPERELKMK.-DFLSFGVSEIISTLLEENIIDCAVMVCEGAGTVLITEPEFAQGVGGRISGVVKTSPIKK..IIEK..LGEEN--VLEPETGKIDQPMGVKKALDQGYNSIAVTVAN..IEDA..VKIRKMDK................----KVYIFAVHLTGI.TRKEAEILF.QNADIITSCASKHIRHIGDKK......ALFKAGYSIPIYAATKDGERFIKKRI-e...
A7IA71_METB6/10-263                  ...................................................................HVIEAIGRS..KIVIKNG..NVAEVS..VSRLRQCPLAKKfARPV.NEITQDEVKANIEH.RMDSWGMCQPHRNVCGA.VDFVGFGASELISTGILSGSLDAAVLACDGAGTVIVTTPEMVQGIGGRMSGLVSTTPLAE..EMDR..IEQGGGIVLDRAKAMVDPVLGTAKAYEKGFTRVAVTVAS..AGTA..LAIREKFP................----EAFIFGVHLSGI.TEEDAERII.GAADIVTACASRWIWQIAGAR......ALLQAGTAVPVFALTKRGKQLILDKI-a...
L0HFE9_METFS/10-263                  ...................................................................HIIEAIGRS..RIVIRDG..VIVEIG..EAQVRKCPLAKRfAYPV.PVITIDAVKANIEH.RIKAFGMCTPDRDVIDT.REFVGFGATELLSFASRAGLIDAAVLACDGAGTVIVKDPALIQGIGGRMSGLVSTSPIAK..VIRR..IEKHGGIVVDKKHASLDQFAGVEWAYDVGYTKVAVTVAR..PEVA..VKIRIAFP................----DTLIFGVHVTGL.TREEAESMV.AAADLMTSCASGTVRDVAGAK......ALLQAGVSVPIFAITKRGKEIIIEKI-r...
H1YXT1_9EURY/5-258                   ...................................................................HIIEAAGMA..RVTVSNG..LVVSVE..EPLLKSCPLARKfGHPV.TKMEIPEIKRNIEE.RISSFGMCTPEREVISD.DDFVLFGASELLSNGLRSGIIDCAVIACDGAGSVVCDNPLLVQGIGGRMSGLVKTVPYRQ..VIER..IEKSGGIVTDRESASVDPLSALKTAVNSGYKKPAVTVAS..AVLS..EKIRSECP................----EAVIVAVHTTGI.LPEDAEVLS.DNCDLISACASLPLRNIAGKR......ALLQAGNSVPVYAMTKTGKEIIFDKL-m...
Q0W683_METAR/4-258                   ...................................................................HVIEGLGRA..RIVVRDG..KVVEVG..EPQISYCPIFDK.HRGI.KKLDPETIKKNIEF.RIQDFGMCTPDRVLKMK.-DFLSFGVSEIVCTAMVKKLIDAAVIVCEGTGTLVVTDPEMVQGIGGRVSGLVSTTPIPE..VIEK..VGREN--VVDPATAKIDQAGGVKKAIDMGYKNIAVSIID..GTGA..KQMKEIEQ...............qHPGVSIYTFVVHTTGM.PEREAELVY.RYADIATGCASKFIREYGARC......NVYKVGDSIPMFGITERGIRLIEERI-r...
Q6LWR3_METMP/6-261                   ...................................................................HVMEVLGNA..KVTVKNG..KVVDVS..DPIISFCPLFAK.HRGI.NEINKESIQKNVEF.RIESFGLFTKNRVVLDD.SPFVGFGTSEIFMSALKKGFLDAVVVVSDCAGTVVTNNPKLVQGLCGRISGIIQTTPIKE..VIEK..IEKANGIVLSKDDASIDQINGVKLAIKLGYKKIGVSVSN..LKDA..LEIKKLEK................-NDIKIITFGVHTTGI.GLSDYDEYL.QYIDLISACASKNLLKSKSFN......IKAQAGSGVPIFALSNSGKELLFERLK....
A0A0W7THI4_9ARCH/8-257               ...................................................................HVFQALGLT..RVVIEDG..KVVSVS..EPKLDYCPLYKK.FRNL.DRITPEAVKENVES.RIREFGLCTENRKVRDG.-DYVTFGISEILSAALAEGKIGAAVIACDGAGTAVVSDPELLQGLCGRISGLLETSPLKV..VQDA..VGKDN--ILDPDGCSIDPLRGADMAAAR-YERFAVTVAS..PHDA..AAIRK---................KYGDRAVVAAVHSSAI.GPKGAQMYF.DNCDLVTACASAPLRKEAGNR......DIVVAGNKVEIYGVTDIGKELVIGKL-a...
G7WK31_METH6/3-254                   ..................................................................e--MELLGRT..RVVVKDG..RVVETG..EPLLRWCPLFDK.VRGI.KEITSEAAAANMEF.RMREHGMFTPARKLEMD.-VFVGFGASEVMMTATRRGLIEAAVTVCDGAGTVVTANPSLIQGMGGWISGLVTTDPIPE..VLAG..IEARGGVVLDPATARIDQVAGAKIAAER-YKSFAVTVAD..AETA..ERLRALEK................ERDVRILVVGVHLTGI.GEEGAERLL.AAADIVTSCASKPLREKVR--......PLVQVGTAVPLFGLTAWGKEVLVERAK....
G7WLT5_METH6/4-265                   ...................................................................HMLEMAGA-..LVRVRDG..EIEVLT..DPKVRWCPLRSG.LYGH.GVESRKTVESVLRG.HMVELGMYGPHRVLELS.DRPVSFGASEMIADAMRSGLVDAAVVVCEGAGTVVAARPEVVAALGAHMTGLIRTEPIEE..IQAG..LRERGCILLDDR-GSIDQVEGYRRALAAGYQRIVVTITGkrAFEA..GEIRKLSSas...........acgQAGEGPVIFAVHNLDV.AEDQAEVLA.ETCDVVWGCASREVREVVGKR......AKLQIGISIPVYALTDSGKRLVLNRA-l...
A0A0E3NYX9_9EURY/3-256               ...................................................................HIMELLGKT..RVVVKDG..KVVEVG..EPEVDWCPLFAK.IRGI.QKITGEEAKKNMEF.RIKDFGMFTDKRKLELE.-DFVGFGASEVMMTGLSRGLLDTTVTACDGAGTVISNNPTLVQGMGGRMSGLVETEPIDG..IING..IQERGGIVLDPSTAVMDPVAGVKKAAELGYKKIAVTVAF..ADTA..KKCRELEA................ELGLDLVVIAVHVTGL.DREEAQALV.ENSDIATSCASKPVRDLVK--......PLAQVGTAVPLFALTQKGKELVIERAK....
O27615_METTH/7-257                   ...................................................................HVIEALGKS..RVTVRNG..RVVDVS..EPLIDYCPLFHK.YRGI.EKITSEAIRQNIEF.RIKDFGMCTGNRELRMR.-DFLSFGISEIISTLIEEGEVDAAVMVCDGAGTVIVTEPELAQGIGGRISGVVETSPEDE..VIGS..IGPEK--VLDPEKATIDQVKGVERAFEMGYDRVAVTVAD..PAEA..ERLREMD-................--GGEIYIFAVHLTGI.DYRGAEKVI.NTADVVTSCASKYIRRIADRR......ALLKVGSAIPVYACTKNGKRFIELRIK....
A0A2V2NBU7_9EURY/1-70                ..................................................................m---------..-------..------..------------.----.--------------.-----------------.------------------------------------------------------------..----..---------------------------------------..----..--------................---CEITILSVCTGAI.EKSDAEILL.K-TDLVWSCASKYINEVIGPR......SIFTTRKIKPIYALTDKGKAIILA---gak.
F4BY84_METSG/4-260                   ...................................................................HLLEMAGA-..RVRVRDG..KVEVLT..EPAIRSCPLRQD.LYGI.KVESKETVKRVLEE.HMAELGMYGPKRVLELE.DKPVSFGASEILSDALTEGLIDAAVLVSEGAGTVVATRPEVLQAIGAHMTGLVKTEPIEE..IQSG..LEERGCILIDRQ-GTVDQVLGFERAVEAGYSRIAVSLAGhrADDA..RALRERER................ALGARATILAVHTTGI.SENEAQVLA.ECCDLVWSCASRSVREVAGGK......ALMQIGIAIPVFALTPMGKRLILNRA-m...
D3E0P1_METRM/4-260                   ...................................................................HVIEALGRA..RITVENG..KVVDVG..EPMIEYCPLFDK.HRGI.KELTKEEIEKNIQF.RIDDFGMCTKNRQLRLK.-DFLSFGISEILSTLLDENLIDCAVMVCEGCGTVLVTESEMAQGVGGRVSGLVETSPISQsfIWKS..FGQDR--VVDSETARIDQVDGLRLAIDNGYKNIAVTICL..AEDG..IILRELEK...............eYEDINVYIFAVHSTGL.GREEAEIIF.DTADVVTGCASKHLRDIGKEL......KVFSVGTSIPIFAASDKGEEFIKLRL-d...
L0HF58_METFS/8-261                   ...................................................................HIIEAIGQC..RIVIRNG..KVVEVG..EPRIRDCPLAKKfAYPI.PDITKESVKANIEH.RIKAFGMCTPDREVIDN.REFVGFGASELLSFGIQAGLLDAAVIACDGAGTVVATKPAMVQGIGGRMSGLASTCPYTQ..VMDR..IEKEGGFVLDRKHAAMDPVAGVALAVEKGFRKIAVTVAG..PDAA..AAIRKIHP................----DTFIVGVHVTGL.TKQEAEDLV.AASDLVTSCASKTIREAVAQK......ALVQAGIAIPVFAMTSRGKELIIEKI-r...
B1L4C3_KORCO/2-254                   ...............................................................hell-----CRGA..RVLVRGC..EVEVLT..DPAVSSCPYVRA.VYKI.ENIDREAVKRILED.KIREFGFFCPHRSLESD.-IAVPFGSSEMISSVMGD-LIDCAVVVCDGAGSVITRNPKLVQGIGARMNGLLKTVPIPE..IIER..IREMGGVTL--EDPRIDQVAAVRRAIEMGFKRIAVTVIGpmARDI..EELRAMES................AESVKLAIFSTCNTLV.-REEDVPYL.EKADIVCASASRIVMERIGPR......ALIQLGVHIPVFVLTSFGKAIAL----ryle
R9T570_METII/1-249                   ...................................................................--MEALGKS..KIIIEDG..KVADVS..EPVVKYCPLFKK.HRNI.EELNCQSIKENIEF.RVKDFGMCTENRETKLD.-YFLNFGISEVMSLAVKQGSLDSVVMASDGCGTAVLNDAQIIQGMGGRISAIIETEPIES..VIAD..IGAEN--ILDPKTAEIDQIKGVIKAYEMGYSNVGVTTPF..AQQA..KFFRE---................KYGDKIVIFGVHTTGI.SEDEANMFF.DYADVITACASKYVREVAKTK......AVIQAGTKVPIYGATERGKELMLAKL-n...
A0A2U1S605_9EURY/4-258               ...................................................................HIIDGLGKS..IITIRDG..KVINVT..EPKVKYCPLFDH.QRGI.KEITKEEVKNNMEF.RIKDFGMCTKNRQLKMK.-DYLSFGISEIISTLIEKEIIDCAVMVCEGCGSLLVFESELVQGIGGRVSGLVKTSPIPE..LIEK..LGSEN--IVNPETAEINQIAGVKKAIEKGYKNIAVTIAL..ASDI..EEINRLKK...............eNSNVNIYVFVVHTTGV.SPEDARILF.DNCDVATACASKNLREIGDKE......SLKTVGQSIPIYAKTEKGKEFLEVRL-e...
A0A1D2W565_9EURY/4-258               ...................................................................HVIEALGKA..RVVVRDG..KVVEVG..EPKINYCPLFDK.YRGI.KEITPEAVKENIEF.RIKDFGMCTSERKLRMK.-DFLSFGVSETLGTLLDEGIIDCAVIVSEGCGTTVVEDPEFVQGMAGRISAFLSTSPIEK..IIVK..VGPEN--VLNPETAEINQIKGVLKAVEMGHKKIAVSVIS..AEDA..KTLREIEK...............eHEGVNIYIFAAHVTEM.SKEEAEELF.DYADVVTGCASKYIREVGEGR......EIFTAGASIPIYGASKDGEHFLKIRI-e...
A2SQB6_METLZ/5-260                   ...................................................................HIIEAIGMT..RIVIRNG..KVVEVG..EPAVDFCPLAKRfATPV.DPITKESVQKNIES.RIKTFGMCTKERQVLDQ.ETFVLFGASELMSTGLRTKTLDAAVICSDGAGTVIVRTPDLVQGLGGRMSGLVSTTPHPE..VIRK..IEESGGIVIDKETAKLDVLAGLTRAKAEGWTKTAVTVAGfqHELA..EEIRAEYP................----EALIIAVHTSGVaSAENAERLV.AASDLVFACASKYVRAAVS-K......ALVQGGVGVPVYAMTRAGKRLIMERL-i...
Q8PT56_METMA/3-256                   ...................................................................HIMELLGKT..RVVVKDG..KVIEVG..EPEVKWCPLFAK.IRGI.QKITPDEVRKNMEF.RISDFGMFTDKRRLELE.-DFVGFGASEVMMTGLSRGLLDTTVTACEGAGTVISNNPTLVQGMGGRMSGLVETEPIEG..IING..ITERGGIVLDPSTAKMDPAAGVKKAAELGYKKIAVTVAF..AETA..KEVRKLES................ELGLDLIVIGVHVTGL.DREEAQALV.ENSDIVTSCASKSIRDLVK--......PLAQVGTAVPLFALTQKGKELVIERAK....
D7DUV9_METV3/7-279                   ...................................................................HIMEALGNA..KITVING..KVISIS..KPEIKTCPLFLK.HRNI.VELNEETIKKNIEF.RIQSFGLFTKDRVIEEK.EQFVSFGTSEIFMTALGKKMLDAVVIVSDCTGTLITPNPYLVQGLCGRISGIVQTTPIKE..VIERvnIANPNGAILDEKTAEIDQVKGVLKAIEMGFKKIGVSVAY..PEQL..NELRQIEKdynl........khndKEPVKICIFGVHTTGV.DFYKYKDEI.PEYDLIASCASKSLYNLLKNDedlkkvLKVQAGKSVPIYALSNWGRDLLLERFK....
A0A0Q4BE22_9ARCH/4-254               ...................................................................HVMEALGKA..RIVIEDG..RVVEIG..EPMVRYCPLFDK.HRGI.KEFNEATIRENMEY.RIGKFGMCTGNREHRMR.-DFLSFGISEIMSLAVKNGKLDAVVLAADGCGTVVLDDPEVIQGLGGRISGLVETEPIPE..LIEK..IGRER--LLDPDTAAMDAFGGVHKAFAMRYGKVGVTLVS..PKEA..AEIRD---................AFGDNVVIFAVHTTGV.TEEEANGLF.DFCDVITSCASLPIRRIAERR......ALLQAGTKVPVYAATETGAEIMMAKL-r...
F4BTJ3_METSG/2-255                   ...................................................................HKMELLGRS..AIKVSEE..EVTEAT..EPVIEWCPLFDK.VRGI.KKVTKESAAANMEF.RIKEHGMFSARRKLEMD.-TFVGFGASESMMTGLMRGIIDAAVTVCDGAGTVITSNGSLVQGMGGYISGLVETDPIPE..VIKG..IKSRDGHVLSPESGRIDQLEGAAYAISAGYCRFAVTVAD..AQTA..ERLRELER................STGVRIMIIGVHLTGI.SKDDARRLL.KAADIVTSCASRHIREEAV--......PLVQVGTAVPLFSLTPWGKELLVERAK....
A0A498H709_9EURY/7-260               ...................................................................HVIEAVGKT..RVVVRNG..KVVEVG..EAIITDCPLAKRfACPV.PEISADAVRENIEH.RIKAFGMCTPERVVLET.REFVGFGASELLSFGIKAGLIDAAVLACDGAGTVVVTDPAMVQGIGGRMSGLVRTTPYPS..VMDR..IEEGGGFVLDRETAAMNPAAGVALAEEKGYRKIAVTVAL..PEDA..AAIREAHP................----DAFIVAVHVTGM.TRDGAATVA.AAADLVTTCASGTVREIAGSR......ALVQAGVSVPVYAMTERGKDLILEKV-r...
A0A2V3JIK1_9EURY/1-231               ..................................................................s---------..-------..------..--RIEWCPLFDK.LHGI.KEITEDAVCANMEF.RIAELGMFTPSRNLDVD.-VFVNFGASEVMMTGLRAGLIDTTVTACDGAGTVITDNPGLVQGMGAQISGLIETEPIQE..IVDG..IRERGGTVVDPDAASIDPAVGVRHAVKLGYTRIAVTVVD..PATA..RLIRRIES................EPGIKVIIIAAHITAL.SRAEVQDLL.DLVDIVTGCASKHVRDLVK--......PLAQVGTAIPLFALTRAGKELVIERAK....
A0A1D3L1T6_9EURY/4-258               ...................................................................HIIEALGRT..RVVVREG..NVVEVG..EPKINYCPIFDK.NRGI.KDITSEAVRKNIEF.RIKDFGMCTSERKLRMK.-DFLSFGVSETLSTLLDENMIDCAVIVSEGCGTVILTDPEFVQGMAGRISAFISTTPITQ..IIET..IGPEN--VLDPETAEINQIKGVLKAIDTGYRNIAVSVVS..TEDA..KKLRGIEK...............dNEDVNIYIFAAHVTEM.SEEDAKVLF.DTADIITSCASKYINEVGKDR......EVFKVGTSVPIFGPTESGEKFLKTRL-e...
E1RD37_METP4/8-261                   ...................................................................HIIEASGRC..RIIVRNG..EVVEVG..EAMIKSCPLTKKfSCPV.YDLDRESVKANIEY.RIKTWGMCTPERKVIEN.REFVGFGASEILSFGLSAGMLDAVVLACDGAGTLVSPNPSLVQGIGGRMSGLVKTVPYEN..VIRR..IEEAGGLVIDKENASLDQMAGLAKAYELGYEKVAVTVAL..PAEA..EKIRQQYP................----DAIIFGVHVTGL.GREEAETLV.SVSDFVTSCASATIREAAGKK......VLVQAGTAIPTYAMTRIAKDIILEKV-r...
R9SLQ3_9EURY/6-259                   ...................................................................HVISTLGKA..EVVIENG..KITSIG..EPKIDYCPIYKD.IDNV.DEITKDYIEMNINR.RIEEFGMCTSKRAIKMG.-DMMTFGISETLETNLELGAIDCVVGACEGVGTVLMTDPDTVQGVGGRVSGLVSTTPLPE..VAEK..LGREN--VLNPETAELNQLEGVKKAIKKGYKNIAVTIIP..SPMV..KEIRELET................PDDVNIYIFVAHTTGA.SKEEVVELF.ENADVITACASSEILDYADKV......KPYYSGKKVPLFAATEKGREFLDNRL-e...
A0A110A2X6_THEX5/1-250               ...................................................................--MQALGMC..RIVVEDG..KVTEVG..EPRLKYCPLFNK.LLGI.EEIDSETVRKNLEY.RVKSFGFGTEERVVRAG.-DYVTFGVSEILSTAVKDGRLDGAVIAADGCGSAVLTDPELIQGLCGRISGMVSTDPLDT..VLDA..VGRDR--VVDPDTTPVDQVRGAELAMKLGLKRFAVTVCR..PEDS..ETIRRMC-................--GNRAVIIAVHTSCV.SEEGAOKFY.ANCDFLTSCASRVIREIAYSR.....pDVVIAGNKIPIIAVTDIGKELVLSKLK....
A0A8J7Y9Q3_9EURY/4-99                ...................................................................HIMEALGKA..KVVVKNG..KVVEVG..EPLIKYCPLFNK.HRDI.KELNKETIKKNIEF.RIKDFGLFTENRIVESK.ECIVKFGTSEIFMTALDRGILEAVVIV---------------------------------..----..---------------------------------------..----..--------................----------------.---------.---------------------......---------------------------....
A0A2Z4L777_9EURY/6-259               ...................................................................HVIEALGKA..RIVIKDG..EVVSID..EPMIDYCPIFGK.YHNI.EHITKDDIRKNIEY.RIKDFGMCTKDRKLRMG.-DMLSVGISEILRSNLKLGNIDCVVGACEGTGTLIMNEADLVQGVGGRVSGLLSTTPIPE..IIEQ..VGEDN--VLDPETAELNQLKGLKMAIDKGYKNIAITIIP..CEMI..KQIREYPL................PDDVNVYIFVAHTTAI.TEELANMVF.ECADIVTACASREIINLAQIK......KPCYYGTAVPILAVSNDGRKFLDARLK....
Q8TYZ1_METKA/6-259                   ...................................................................HMMECLGKTpvRVIWKDGdvEVRAEG..DPMIERCPLMRR.REGF.SKLTREAAERHVLN.KVNEVGMFTPKRRIRSC.RRYTPFGVSETLMTCLQHRLIDAAVIVSDCAGTVVTDKPAIVQGLCGEISGIRDTDPIPE..VVDR..LEDSGCSVL----GRIDQREGVEIALEEGRRFVAVTVAD..AGDA..EAIRE---................EFGDDVLIAAVHTTGT.DEEDAERLV.QYCDIITGCASKAVRRAAGRR......YILKVGSRVPVYGITPAGAEALWL---nvr.
D7E9Y3_METEZ/3-256                   ...................................................................HKMEMLGKT..KVTVKDG..KVVDVS..EPVISWCPIFDK.VHGI.KKITPEDVKKNMEF.RINDFGMFTDKREIEQE.-VFVGFGASEIMMTGLRRNVLDSTVTVCDGAGTVITSNPKLVQGMGARISGLVETEPIEG..LIER..IQKSDGVVLDPYTAKIDPIEGVRKAHELGYKRIAVTVPG..VDEA..KKLRDLES................ELGLELILIGVHITGI.ERDKALQLI.EYLDITTACASKNIRDVIK--......PLVQVGTAVPLFGITQRGKEIMLERAK....
A0B9J8_METTP/2-254                   ...................................................................HIMELLGRC..RVKIQDE..KVVETT..EPLIEWCPLFDK.VRGI.KRITPEAAAKNAEF.RMREHGMFTPRRKLEMK.-TFVSFGASETMMTGISRGLIDAAVTVCDGAGTVISDSPSLVQGMGGWISGLLETEPIPE..VIEY..IKKKGGIVLSPGDARIDQLEGARIAAQK-YRRFAVTVTD..AETA..FKLRELEK................ETGCRILIVGVHLTGI.SRDDAERLL.SAADIVTGCASKHIRVLVK--......PLVQVGTAVPLFGLTQWGKELLVERAK....
Q8TUM7_METAC/11-265                  ...................................................................HIMEIMGKT..RVVVKNG..KVIEVG..ESELEWCPLIDK.LSGV.QKITSEEVKKNVES.KIRDYGMFTTKRQLLGH.DTFVAFGASEIMMSGLRSGFLDATVTACDGAGTVISGNPELVQGIGGRMSGLVETEPIEN..VIDR..IQKLGGIVLDTKTASIDPVGGVKKAAELSYKKVAVTTAD..STTA..KKLRKLEA................EFGLDLIVIAVHVTGV.SNEEAQGLL.ENSDLVTGCASKYIRELAK--......PIIQVAAAIPLFVLTQKGKELIIERIK....
F7XM64_METZD/3-256                   ...................................................................HIMEMLGKT..RVVVEDG..KVIEIG..EPMIEWCPIFDK.VRGI.RQFTPEEVKKNVEL.RMKDFGLFTKERKLDQP.-VFVGFGVTEVMMTGLERDMLDTTVTVCDGAGTVITSNPSLVQGMGGRISGLVETEPIDE..VINR..IESLGGIVLDPSTAKIDPVEGVKKAALLGYKRIAVSVID..LDTA..IKLHEVES................ENEIDLTVIGAHLTGI.DMEDARELV.KHLDIVTACASRSIRDIVK--......PLVQVGTSIPLFAITKKGKELLLERAK....
A0A328SIC9_9EURY/154-231             ..............................................................lxlel---------..-------..------..------------.----.--------------.-----------------.------------------------------------------------------------..----..---------------------------------------..----..--------................PSGVNVYIFVAHTTGV.DEVIAEELF.DNADIVTACASKSISKLANEK......KPYYYGTAVPIFAVSDEGKFLLDARLK....
D1YXD5_METPS/4-257                   ...................................................................HIIEALGKA..RIKIKNG..KVVEVG..EPLLNYCPIFDK.FRGI.KHLDRKSIQENIQF.RIDDFGMCTANRKLRMR.-DYLSFGISEIISTAMELGILDSTVMVCEGCGTLVITDPEMAQGIGGRVSGLVSTTPIPE..LIEK..IGPEY--ILDPKTARMDAIAGVKKAIAMGFKNIGVSVIS..SKAA..KELKQLEK................EHGVNIYVFVVHTTGM.SEAEAREVF.KYADVITGCASKYVREQGMES......GAFKVGDSVPVFGITPRGQHLIEERIK....
Q8TNR3_METAC/3-257                   ...................................................................HIMEMMGKA..RVVVKDG..KVMEVG..APEVEWCPLFVK.LRGV.QKMTPEEIRKNMEV.RISELGMFTERRKLEFE.TTVVAFGASEVMMSGLKNGFLDTTVTACDGAGTVISSNPALVQGIGARMSGLIETEPIDA..VIKG..IEERGGTVLSPSTAAIDPAGGVRKAAELGHKKIAVTVAD..AETS..RQVRKIEA................GLGLNLLVIAVHVTGV.SQEEAQGLL.DNSDIVISCASKHIRELAR--......PLVQVAAAIPLFALTQKGKELVIERAK....
A0A2V2N2E7_9EURY/7-192               ...................................................................HVIEVAKA-..TLQITDD..EIKVLT..GPKIEFCPTWQK.VLGLsGELNEDTIKEIIEK.RIHIAHLFKSDRMIENQ.NLIFSFGASELLHCSLKIGIIDVAIIVCDGAGTVISNNPDIIQGIGGWMSGIIKTSPIPG..LITR..LKDRGVNIVDEETAAIDPVKGVQMAIDLGYKRIAVTVAEryISQI..DSIRQIES................----------------.---------.---------------------......---------------------------....
A0A1V6N4Y2_METAZ/4-262               ...................................................................HIIEAMGRA..KITIRDG..KVIDIE..DPKIEYCPLFHK.HRGI.EKLDKESIKKNIEF.RMADFGMCSEDREIKMK.-DFLSFGISETISTLLNQNIIDCAIMVCEGCGTVIVETGEMAQGIGGRVSGLSETKPIPK..IIGK..IGEKN--VLDPKNALIDQIKGIELAKSKGHKNIAVTIAN..PDDA..ENIRKLEKky...........nenGEKINIYIFSVHNTGI.KREGCEQLF.EYCDVITSCASKDIRDIGDEK......SKKKVGESIPIYAATNKGKYFLELRL-e...
M4YU01_THEXX/5-256                   ...................................................................HVMEVLGMA..TVVVSDG..KIVEMR..PPVLRYCPMFNK.MRNI.ETIDEDAVRQNIEF.RIRDFGLFTEDRVVRAP.-DIVTFGVSEILNKAIRDGKIDAAVIVADGCGSAVVTDPEVLQGLCGRISGIIETSPLNV..VLDA..VGRDN--VVDPRTTPIDQAAGAALAFSKGFRKFAVTVSR..PLDA..LAIRK---................AFGDSAVIVGVHTSTL.NRKQAEMLF.DNCDFTTACASGPIREIMMSR.....kDVLIAGNKVQIVAITDFGKDLVGSKL-e...
A0A315XP45_9EURY/6-261               ...................................................................HVIEALGKV..RVVIENG..EITEVG..SSDVKYCPMFHA.MHGV.EELNEEFIRKNINF.RIKDFGMCTPERIIEMD.-DVVTVGISEILKTNMEMGNIDCVVGACEGSGTVLMTNSRVVQGVGARVSGLVSTTPIPE..VIEN..LEARGSTVLNPETAELDQLEGLKLALDMGYKNIAITILP..SPMV..EEIRNYSV................DDDVNVYIFVAHTTGS.TPEEAEMLF.ENADIVTACASKAISDYTDEH......KPYYYGLKVPIFCASEAGREMLDNRL-e...
A7I529_METB6/9-262                   ...................................................................HIFETVGKC..RIKVHNG..QVVEIG..EPRIRGCPLAKRfEIPV.DEISKEGIKKTIER.RIRSFGMCTARRKVISD.KEFFGFAPAELLACGLRSGMIDAAVIPCDGAGTVIITNPSMVLGIGGLLSGLIFTTPIPE..VMDS..IEENGGVVFDRATARLDPVGGALLAHRRGFSRIAVPVSD..PKIA..ETIRAFYP................----AALIFGVHLSGI.TGEGARRIV.AVSDLVTGCASKTIRAIGRKK......ALLQVGAVIPIFALTHRGIELIMKRV-l...
D1YVK2_METPS/7-261                   ...................................................................HVIEGLGKA..RIVVRDG..KVVEVG..EPMISYCPIFDK.HRGI.KKFDREVIANNIEF.RIKDFGMCTPDRVLTMK.-DFLSFGVSEIICTAIRQKKVDAAVMVCEGCGTLVVTDPDMVQGIGGRVSGLVSTTPIPA..LIEK..VGAKN--VLDPKTAKIDQAAGVKKAIAMGYKNIAVSIID..GTMA..KQMRDIEK...............qHPGVNVYTFVVHVTAM.PKEEARLVF.EYADVATGCASKYIREEGTKK......AVCKVGDSVPIFGVTPRGQALIEERIK....
A0A1F2P745_9EURY/4-263               ...................................................................HIIETLGKT..KVFVEDG..KVVKVEhaEKRLEYCPVVEK.VFGI.QNLMDDSARLGVER.RIERWGMCTPARKIKETtESFVSFGASEILSNALNDGLIDAAVTVCDGAGTVITDQGDVMQGIGVAMSGLTLTSPIVE..VIRN..LEGEGAIILDPERASIDQVAGLERAFKD-HDCVGVTLTS..PDVA..KMCRDVEK...............aNPGKKAVLFGVHTTGL.SRDDAKALI.DTVDLTTGCASRHLRSQIGEM......ALLQVGRSVPIFAITQTGKELILNRMK....
A0A1F2P8Y1_9EURY/10-266              ...................................................................HVIEIAGKT..RVVIKNG..KVEEVG..EPLVKSCPLWKD.FFGL.DEFTREFIAERVQKvMIEKRGLFTERRTFELL.-PEVDFGVSEMMMDARRDGLIDVAVEVSDGAGTVIVGDPELIEGIAGQMPAVIVASPIPD..VIDR..LEAGGAVVLDPATAKIDQVAGVERAIELGYKKIGVSVIR..AEDA..KRLRELEE................KSGTEITIFTVHTTGL.AQWEVEAMA.EHVDVITACASESIREIVGRR......ALIQIGTKIPLFALTKRGKRIILNRA-m...
W9DRC6_METTI/3-256                   ...................................................................HVMELLGKA..RVVVENE..KVVEVG..EPLIGWCPIFDK.ARGI.TEITKEEIRKNMEF.RIKDFGLFTNKRQLDMD.-IFVGFGASETMMTGLTSGLLDTTVTACDGAGTVISNNPNLVQGIGARISGLVETEPIDE..TING..INERGGIVLDPSTARIDPVAGVRKAAQLGYRKIAVTVVF..PETA..RQLRDLEK................ELDIELVIIGAHVTGI.NKQAAQGLI.DSTDILTSCASKHVRELVQ--......PLVQVGSAVPLFGLTKRGKDLLLERAK....
F4BW83_METSG/4-260                   ...................................................................HIIEMAKA-..LVKVKDG..MIEVLI..KPTIRHCPLRND.LYGF.EEENHKTVEKVLRR.HIEEFGMYGPNRVLESD.QKPVSFGASEIIVDAMTEGLVDAAVVVCEGAGTVIITRPEVLQAVGAHMTGLISTEPIKE..IQDG..LKQKGCLLLDKQ-CTIDQVEGYIMAVEAGFRKIVVTITGhkASEA..KRLQELGE................ISGVKPVVVSVHNTGI.SVEEAETLS.DYCDIVWACASKQVREIVGKR......SKLQIGISIPVFGMTQAGKQLILNRA-l...
A0A2V3JFY8_9EURY/9-258               ...................................................................HVIETLGRA..RVVVEDG..KVVEIG..RPVLKYCPLWAK.IRGI.EEINEQVIKDNVEF.RIRDFGMCTAARALELD.-VFVGFGASETLMTALHKGLLDATVTVCEGAGTVITSNPALVQGIGARLGGIIETSPVGA..ILRG..ISERGGVTLVPP--AIDQPAGLRIALRMGYKRVGVTVCT..VEDA..EQCRAISE................----DAIIFGVHLTGI.TRGDAERLF.QVADLVTACASRYIRELANER......AILQAGTAIPIFALTPAGKELLLERAK....
A0A483CNS0_9EURY/5-258               ...................................................................HIIEAIGRA..RVVVRDG..QVVEVG..EPLIRSCPLAERfGRPV.REMTKEAIRENIEE.RIRSFGMCTPDRKVLAD.PDFVLFGASELISCAIRNGLLDSAVIACDGAGTLVAQNPRLVQGVGGRMSGLVKTSPIPP..VIER..IEANGGRVLDPATAPIDQVKGVGLARDMGCRRVAVTVAG..AAEA..EEIRRLYP................----ESIIVAVHTTGL.SAKESERLV.AVADIVTVCASLHLREAAGRV......ALLQGGAAIPVFALTQQGKDVILEKI-r...
E3GYC0_METFV/5-253                   ...................................................................HIIEALGKT..KIIIRDG..NVEYVG..KPLIKYCPIFYK.YRGI.KKITRKAIKENIEF.RIKDFGMCTPKRKLYME.-KYLSYGTSEIISSLLQDKILDCAVMVCDGAGTVIVNDPMLAQGIGGRISGIISTTPIET..IIKT..IGEDN--VLNKKTAEIDQVKGVKKAIDKGYKSIAVTVTS..VKEA..IEIRKIAP................----RACIFAVHLTGI.SKNDAEKLF.EVADIITSCASKYIRKIGDKK......ALLKVGRSIPVYAATKKGKKILLK---fk..
B8GFH3_METPE/8-261                   ...................................................................HVIEAIGRS..RIVIRGG..EVVEVG..EARITTCPLAKRfALPV.PTINKDAVKANIEY.RIRTWGMCTPQRDVLDT.REFVGFGASEILSFGLHTGLIDAVVLACDGAGTVIVTTPALVQGIGGRMSGLVSTTPYPE..VIHR..IEENGGVVIDKAHARLNQTAGVKRALELGYKKVAVTVTL..PNDA..KTIRNLYP................----DTIIFGVHVTGL.TPDEAETFA.ASADLMTSCASKTVREIIGRH......ALMQAGVAIPIFVLTSKAKDLIIEKL-h...
A0A062V0M5_9EURY/8-263               ...................................................................HVMEALGKT..RVVVENG..KVVEIG..EPQTEYCPIFDK.VRGI.KKFTPKTAKENIEF.RMRDFGMFTEDRAIEME.-VFVGFGASETFMTGLRRGLIDTCVTACDGAGTVITSNPKLAQGMGSRISGLVETTPIPK..LIDR..IHNVGGIVLDPDTAVIDQVAGVRKAIDLGYKKIGVSVTN..VKDI..REIRDLEK................KHDVQVAGFGVHTTCM.PGDEAKEFI.NLVDMTTGCTSKWIRGQIEGK......ACAQFGTAIPIFAITQRGKELLLERAK....
A6UTW8_META3/5-277                   ...................................................................HIMEALGKS..KIVVKNG..KVVEVG..EPLIKYCPLFAK.HRGI.NELNKDTIKENIEF.RIKEFGLFTENRVVETK.EYVVGFGTSEIFLTALKNKLLDAVVIVSDCAGTIITDNPYLVQGLCGRISGIIKTTPIPK..VIEK..IENAGGVVLNKENAEINQYKGVKKALELGYKKIGVSIGN..LEDA..KKIKELENqiitnaecsikaksdpVQDVKIITFGVHTTGY.SKLEFKKFV.KYFDLTTCCASKGVLGAVKGH......VKIQVGKSVPIFALSQNGKELIIERMK....
M9SBN7_METAX/10-260                  ...................................................................HVFQAIGLA..KVVIEDG..KVVEVG..QPRLNYCPLYKK.FRGM.EEITPEAIKENIEF.RIRDFGLCTENRKVRAD.-DYVTFGVSEILSTALAEKKIDAAVIAADGCGTAIITDPGLLQGLCGRISGLMETSPLQV..VLDA..VGRDN--VVDPEETPIDQMKGAEMADRKGYGKFAVTVAR..PKDA..EALRK---................AYGDRIVVVAVHTSCI.NHEGAQTYF.DNCDIITACANAPLRKEAENR......DIVVAGNKVEVYGVSETGKKLVIDKL-a...
A0A0X3BKZ5_9EURY/1-67                ...................................................................---------..-------..------..------------.----.--------------.-----------------.------------------------------------------------------------..----..---------------------------------------..----..--------................------MIVGVHLTGI.SQEDAALMA.GTADLVTACASRHIRDEAAKT......ALLQAGTSIPVFAMTRAGKAIILAKA-e...
A0A8J8C8Y6_9EURY/1-209               ...................................................................---------..-------..------..------------.----.---------KNIEF.RIKDFGLFTENRIVESK.ECIVKFGTSEIFMTALDRGILEAVVIVSDCAGTVITNNPYLVQGLCGRISGIVKTTPIPK..VIEK..IENAGGTILNKNTGEIDQYRGVKLALELGYKRIGVSIGN..LKDA..EKIKKLEN................-KEVSIITFGVHTTGY.SSSEVRRYL.KYLDIITCCASKGVLEAVKGH......IMVQMGKSIPIFALSKRGKELLLERAK....
A0A1Y3GEN4_9EURY/6-255               ...................................................................HVLELLGKT..RVVVENG..EIIEIE..EGEVDYCPLWHK.MHGV.EKLK-EGAKWQVKR.LMDEIGFCTEDREIEMD.ERIVTFGTSETIMTALENNELDISITVCDGAGTVLTSNPKIVQGIGGRLSGITETTPNKK..IINK..LEQKNAQTLDKP--RIDQPAGLKKAIEQGYKKPAVTVST..VEDA..VKCREISK................----EAVIFGVHLTGV.NKKQTQKLI.ETCDVLSGCASKTIREIAGKK......ALLQAGRSIPIFALTKKGRNLTLDQA-k...
A0A6B9TBV7_9ARCH/4-255               ...................................................................HVMECLGMS..RVTIEDG..KVVEVT..EPKVRYCPLFAK.RRGM.EELNKESIRENIEY.RINSFGMCTENRVTTMD.-NFLNFGISETLCSALKNGKIDAAVIAADGCGTAVITDPSLVQGMGGRISGICETEPIPK..VVEA..VGREN--MLDPDTARIDMEAGVDKAFSMGYERVAVTTPF..VDSA..ERMRG---................KYGDRLIIIGVHTTGM.SEEDSVKAF.DNFDIITACASKYLREECLRR.....pETLVAGNKVPVYGVTPIGRELMQDKL-d...
A0A396QG24_9FIRM/105-381             hitrmfgsfvylkrirgklkavhatpiplrycplmkkllteiggdtaaglleavaqgaedsaglmce---------..-------..------..------------.----.----------LIDE.VVIKGGYFDTSRPLNSC.EVNVLFGASETMSSAFEAGLIDAAVIVSNNLGTIITTGQSNTQGAVRRMTGLFATSPSKT..ITET..AVKAGICPVFPHTGIIDQLEGVRKAISLGYRRIAVSVAW..EDNIilEEIRKLER................-DGIIIYKFALCSTGL.GEDAARAMS.SEADLVWSCSSRAVKTWIEPR......ATAQVGIKIPVYIMDRKGWLLAEN---hlr.
A0A1F2P597_9EURY/11-267              ...................................................................HVIELAGKT..RVVIKNG..KVIEVG..EPIVKSCPLWRD.YFGL.EEFTKEFIHDRVQRiMIDKRGLFTERRSFELL.-PEVDFGVSEIMMNGCEDGLLDVAVEVSDCAGTVIVPDPELIEGIAGQIPGVIRASPIKK..VIDE..LEARGALVLDPATAKIDQVEGVRRAIELGYRKIGVSVID..AGDA..KRIREIER................DTGVHVVIFAVHTTGL.NREEVEEMV.AHVDVITACASETIREFAGKH......ALVQIGVKIPLFALTFRGKELVLNRAK....
A0A166CH84_9EURY/4-258               ...................................................................HIIEAMGKA..RVVIMDG..KVVEVG..DPKIDYCPLFHK.HRGI.EKIDKDTIKENMEF.RIRDFGMCTPNREIEMK.-DLLSFGVSETVSTLLDDKILDCAVMVCDGCGTVLVKNGKNAQGIGGRVSGYIKTSPIKE..IIEK..VGEDN--VLDPETAIIDQIAGTKLAIKKGFKNIVTTITK..GTDA..KKLRELEK...............eYDDVNIYIFSVHSSGI.SDDEAKQLS.KHCDVSTGCASKAMRNIGEKE......SVLKIGESIPIFACSQAGKEFLERRI-e...
A0A328SIC9_9EURY/6-157               ...................................................................HIIEALGKT..RVVIEDG..IITNIS..EPEIDWCPIFAK.YHNI.KHITREDVRRNIEY.RIDDFGMCTAKRQLKMN.-DMLSVGISEILRSNVKLGNIDCVVGACEGVGTVLMTDPDVVQGVGGRVSGLVSTTPIEE..IISQ..LGVEN--VLDPSTAKLDQL--------------------..----..--------................----------------.---------.---------------------......---------------------------xle.
D5EBB8_METMS/3-256                   ...................................................................HVMELLGKT..RIVVRDG..KVIEVG..EPAVKWCPLFDK.LRGI.KEITPEAARENMEF.RIKDFGLFTSERKLEQD.-VFVGFGASEVMMTGLNRDMLDTTVTVCDGAGTVITNNPKLVQGMGARISGLIETEPIDA..VING..IAEKGGIVLDPATAEINPEGGVLKAAKLGYRRIAVTVVH..SENA..ARLRQLEA................EDDLDLLIIAAHTTGL.GKEEAMELF.QHVDITTGCASRQIRELIK--......PLAQVGTAVPLFALTQKGKEMLLERAK....
A0A0Q4B9C2_9ARCH/4-254               ...................................................................HVIEALGCT..RIVIEDG..KIVEIG..QPRATFCPLFLK.TRGI.TELNEESIRKNIEF.RIQDFGMCMPNRKMRMR.-DFLSYGVSELIGMALTKGMIDAAVMVCEGTGTVVVSDPELAQGIGGRVSGIIETSPIEE..IIQA..VGRDH--VLDPERATIDQVKGAEMALSLGYRRVAVTVAR..AEDA..LEVRR---................RLGQRSAIFAVHTSGL.SAEDAETLF.DVCDVITACASRAVRDAARRR......ALYQVGNKVPIYAASLWGEVLLKTRV-e...
I7KZB0_METBM/7-260                   ...................................................................HIIEAAGKC..RIVVRDG..RVVDVG..TPQLDDCPLARRfACPV.REMTPDAIRENIEA.RIRSFGMCTPEREVLAG.PDFVLFGASELLSGAIRQGLLDAVVIVSDGAGTLVAKDPALIQGIGGRMSGLVFTSPIPE..VIAR..IRENGGVVLDPKTAAIDQVAGVALAATLGHRRVAVTTAD..AAEA..VAIRDRFP................----EAVIVGVHLTGI.SQEDAALMA.GTADLVTACASRHIREEAAKT......ALLQAGTSIPVFAMTRAGKAIILAKA-e...
U6E9T3_9EURY/4-258                   ...................................................................HVMEAMGKA..KIVIRDG..KVVEVG..EPRIDYCPLFHK.YRGI.EKITPQVIKDNMEF.RINDFGMCTNQRELKMA.-DFLSFGISEILGTLLDEEIIQCAIIVCEGCGTVIVEDPELAQGMGGRVSGIISTSPLPE..LINS..LGSDK--VLNPENAEINQVKGVLKAIDDGYTRIGVTIAN..ADDA..KIIREIES...............kNEGVKIYIFAVHNTAA.SAEGAKVLF.ENADVITGCASLQIRNLAKEK......DVFSVGASIPIYAASNDGEKFLKLRI-e...
Q0W8U3_METAR/4-258                   ...................................................................HVMEALGRA..RVVIRDG..KVVEVG..EPELKYCPIFDK.FRGI.KELTKEEIRKNMQF.RIDDFGMCKADRKLRMR.-DYLSFGVSEMISTAMANGMMDAAVIVCEGCGTVVLDEPDMVQGIGGRVSGLVSTTPIPE..LIQR..IGKDR--VLEPETAKIDQIEGAKKAIAMGYKNIAVSVAK..GSQA..KKIKELEK...............aNPGVNLYTFVVHTSGM.SEDEAVEVF.NYADIATGCASKHIRGIGHGK......QVYYVGDSVPIFGITARGRQIIEARL-r...
A0A0X3BLF2_9EURY/7-186               ...................................................................HIIEAAGKC..RVVVRDG..RVVEVG..TPQIDDCPLARRfACPV.REMTPDAIRENIEA.RIRSFGMCTPEREVLAG.PDFVLFGASELLSGAIRQGLLDAVVIVSDGAGTLVAKDPALIQGIGGRMSGLVFTSPIPE..VIAR..IRENGGVVLDPKTAAIDQVAGVALAATLGHRRVAVTTAD..ATE-..--------................----------------.---------.---------------------......---------------------------rrls
Y054_METJA/4-257                     ...................................................................HVMEALGKA..RVVVENG..RVVEVT..EPKIKYCPLFAK.HRGI.KEITKESIKENIEF.RIKDFGLFTKNRVVEES.RYIVPFGASEILMSALKRKAIDVAVIVADCAGTIITSNPNLVQGLCGRISGIIETSPILE..VIEK..IEKAGGVVLNKKTAEINQFEGVKKAIELDYKKIAVTVTN..LEDA..KRCKSLEN................-DEIKILTFGVHLTGI.--EGSEEIA.KYFDLVTACASKVLREKLKGK......IKAQIGKTIPIFALSDFGKEILLERAK....
A0A2V3JR45_9EURY/3-256               ...................................................................HIMEMLGTS..RVTVEDG..KVVDVG..KSRIEWCPLFDK.LHGI.KEITEDAVCANMEF.RIAELGMFTPSRNFDVD.-VFVNFGASEVMMTGLRAGLIDTTVTACDGAGTVITDNPGLVQGMGAQISGLIETEPIQE..IIDG..IRERGGTVVDPDAASIDPAVGVCHAVKLGYTRIAVTVID..PANA..LLIRRIES................EPGIEVIIIAAHITAL.SRAEVQDLL.DLVDIVTGCASKHVRDLVK--......PLAQVGTAIPLFALTQAGKELVIERAK....
E1RJI0_METP4/6-261                   ...................................................................HIIEVAKG-..RIQISDG..EVTVIS..KPKIKSCPTWQR.VLNIsGELNEPIIKEIIER.RMELGKLFQPDRILESD.NLIFSFGASELLFCALNEGIIDAAVLVCDGAGTIISDKPKVVQGVGGWMSGMIKTSPIPE..IISR..LEDLGTIVVDKENAIINPLYGVQKAIENGYRNIAVTVAEndIDLI..PKIKELEN................--GCNISILSICTGAI.SKKEAQILT.Q-ADLVWSCASKEINEVVGPE......SIFTTRRCKPIYALSTKGKKMILS---gas.
A0A8J7UQW8_9EURY/4-257               ...................................................................HIIEAAGKT..RVVVRDG..KVVEVG..EPVIRSCPLAERfSSPV.REMTREEIKKNIEA.RIRGFGMCTPAREVLAD.PDFVLFGASELMSAAVRRGDLDAAVIACDGAGTVLARNPRLVQGIGGRMSGLVKTSPIPA..VIRR..IEENGGTVLDPATARIDPVSGVEAAVQAGHQAVAVTVAS..PAVA..VEVRRRYP................----DVLIVGVHLTGL.SVDEAEQMA.AVADIVAVCASRHLREAAGRR......ALLQAGTAVPVFALTQRGKEIVLDKI-r...
F6BBW8_METIK/5-259                   ...................................................................HIMEALGKA..KVVVKNG..KVVDVG..EPKIKYCPLFDK.HRGI.KEIDKESIRKNIEF.RIKDFGLFTENRIVEVE.DCIVGFGTSEIFMTALRRGLLDAVVIVADCAGTVITNNPKLVQGLCGRISGIVKTSPIPK..VIER..IEKAGGYVLDPKTAEINQIKGVEKAIELGYKRIGVSLTN..LEDA..IKCKSLEN................-EEIKIITFGVHTTGI.-DENPEELT.KYFDLITACASKMVREGLKGK......IKAQIGVSVPIFALSQIGKELLLERAK....
A0A165ZJG0_9EURY/4-258               ...................................................................HIIEAMGKA..KVIIRDG..KVVEVG..EPQIEYCPLFHK.YRGI.EEITKETIKENMEF.RINSFGMCTPSREVEIA.-DLLSFGVSETLSTLLKEEIIDCVVMVCDGCGTVLVKEPEKAQGIGGRVSGYVKTSPIPE..IIEN..VGKEN--VLNPKTAEINQIAGLSLAIKKGYKSIAVTIAS..AEDG..KKLREIEK...............eNKDIEVYIFSVHSSGI.NNTEAEDLS.KYCDVSTGCASKCMRDKGENN......AIFKVGESIPIFAFTENGKFFLEKRL-e...
F0T748_METLA/4-258                   ...................................................................HIIEALGKA..KIKVKNG..KVVEVG..EPKIDYCPIFDK.YRGI.KKLTPETIKENIEF.RIEDFGMCTEDRTMRMH.-DFLSFGVSETLTTILKEGEIDAVVSVCEGCGTVILTEPELVQGTGGRVSGLVSTCPIEK..LMEE..VGQDN--VLDPANASIDQIAGTMKAIEMGFKKIAVTIVS..ADDA..IRLREIEA...............eNKDVNIFIFVAHVTEM.SEENAITIF.NHADVVTGCASKYIRNIGKEK......EYFVAGDSIPIFGVTDTGKRFMELRI-e...
A0A062V1M8_9EURY/6-263               .................................................................hk--LQMV-KA..DVVVDNG..SISVLT..DPRLEKCHMRSK.GFGH.DRETKETIRNVLSK.HMEKLGLFSDARVLELS.ERTIAAGASETLADSIREGMLDCAVTVCDGAGTVVSSKPGIVQAIGAVIPWLSETTPIPE..TQSE..LKQHGSYLIDDK-ATIDQVRGVELAAMHGYKRIGVTMVGikSSIL..RELRRVEK................DKGLQLTALVVHNSEM.TEEDARTLLnENADIVWGCASEVVRAIIGPK......AVLQMQGPVPMFALTERGKRCALARI-a...
A0A4E0PXD3_9EURY/3-256               ...................................................................HIMEIMGRT..RVVVEHG..KVIEVG..EPQIRWCPIFEK.ARGI.KEITKEEVRKNMEF.RIRDFGLFTAERKLEMD.-VFVGFGASEVMMTGLDRSIIDTTVTVCDGAGTVITNNPTLVQGMGARISGLVETEPIDA..VING..ITERGGIVLDPSGATIDAVAGVKKAAHLGYKKIAVSVVF..PETA..KQLREFEK................EMGLELILIGAHVTGI.DRTFAEGLV.KHVDIITGCASKNIREIIR--......PLAQVGTAVPLFAITQKGKELLLERAK....
A0A0A7LD54_9ARCH/5-255               ...................................................................HVIECLGMS..KVIIEDE..KVTVVS..GPKVKFCPLFKK.YRNI.DEITEEVVKSNIEF.RIESFGMCSERREIRMM.-DFLSFGISEVLSSSLKHSKIDAAVIASDGCGTVVLTDPEIVQGLGGRISGVCETTPIES..VIDG..VGREN--VLDPDTAKMDMIAGVRKAKKTGFGTVAVTVVS..MADA..SELRR---................EFGDSVVIMAVHTSCM.NKKDARTAF.KVCDIITACASETLRAEAKTK......DIIIAGNKVPIYGVSEKGKELVLMRLK....
A0A0E3NWD7_9EURY/3-257               ...................................................................HIMELLGKA..RVVVKDG..KVVEVG..PPEVEWCPLFDK.LRGI.RKITAEEVRKNIEF.RISDFGLFTDKRQLLEL.DTYVAFGASEVMMSGLRRGFLETTVTACDGAGTVISGNPPLVQGIGGRMSGLIETEPIAK..TIKG..IRENGGTVLDPSGAAIDPAGGVRKAAEMGYKRIAVTIAD..AKTA..KNCREIEA................ELGLDLIVIAVHVTGV.SREEARELL.ENSDIVISCASKHIRELAK--......PLVQVAVAIPLFALTQKGKELVIERAK....
A0A328S6R4_9EURY/6-259               ...................................................................HVIEALGKT..QIIIEDG..KITSIG..EPEIDYCPIFGK.YHHI.EKISKEDIRKNIEY.RIADFGMCTRDRILKMD.-DMLSVGISEILRSNVELGNIDCVVGACEGAGTVLMTDSDIVQGVGGRVSGLVSTTSIPE..IIEE..LGKDN--VLNPETAELNQLKGLKMAVERGYKNIAVTILP..GSMV..HDLRSFSV................SNDVNVYIFVAHTTNT.SKDEVEQLF.EDADIVTACASKNIIEYAQLK......KPYYYGTSVPIYAVSEDGRRLLDARLK....
Q8PT59_METMA/3-257                   ...................................................................HIMEMMGKA..RVVVKDG..KVIEVG..IPEVEWCPLFVK.LRGV.EKMTPDEIRKNMEA.RISELGMFTENRRLEFE.TTVVAFGASEIMMSGLTSGFLETTVTACDGAGTVISGNPALVQGIGGRMSGLIETEPIDA..LIRG..IEERGGTVLDPATATIDPAGGVRKAAELGYKKIAVTIAD..AKTA..KNVRKIES................ESGLDLFVIAVHVTGI.SREEAQELL.DNSDIVISCASKYIRELAK--......PLVQVAAAIPLFALTKKGKELVIERAK....
A0A484F367_9EURY/3-264               ...................................................................HVMEMVGNA..RVVVENG..KVIEVS..EPEITWCSLFEK.ARGI.QKITPEEIKKNMEF.RIEKFGLFTPNRLLDDF.EDFVGFGASETMMSGLQHGIIDTSVSVCDGAGTVITNNPSLVQGMGARMSGLVETSPIPE..TIQK..IKDRNGIVLDETTAVIDPFAGAKKAVDLGYRKIAVTTAN..AQTA..AEIREIEKeyne........nsggYGGVSFTIIGVHTTGL.SREESKTMA.ENADIITLCASKCLREIKP--......-MLQVGTSVPLIALTQNGKELLLERAK....
Q2FU23_METHJ/4-257                   ...................................................................HIIEAAGRC..RVVVRDG..KVVEVG..SPLITECPLARRfACPV.NEMTSEAIRDNIQN.RIDSFGMCTPGRELTSD.EVFVGFGASEIISTALKSRFIDAAVIVCDGAGTVVVTKPEMAQGIGGRMSGLISTSPIPD..VIRR..IEDEGGIVVDPDHAFLDPIAGVRAAKMAGYEHLIVTIHN..PEDA..RAIREYDS................----DAIIIAVHTTGY.SHEDAEKVK.QYADIVTACASQTIREICGPC......AILQAGSTVPVYALTSGGKHLILLRM-a...
L0KZ42_METHD/3-256                   ...................................................................HVMEILGMA..RVVVKDG..KVTEVG..EPQLDWCPLFEK.ARGI.KHINSEEIRKNMEF.RIRDFGLFTPQRKLDMD.-VFVGFGASEVMMTGLNRGMLDATVTVCDGAGTVITANPRLVQGMGARISGLVETEPIPE..VIAG..IEQRNGIVLDPQHASIDPVQGLQKAAQIGYKKVAVSVID..ALTA..SKLREIES................AQGLDVCIIAAHTTGL.TKEHASELL.KYTDIVTACASRNLREIIK--......PIAQVGTAVPLFALTQKGKELLLERAK....
A0B8M2_METTP/4-260                   ...................................................................HLAEMA-KA..LVRIRDG..KPEVLT..SPLIRFCPLRRD.LYGI.DEESRETVEEVIRS.HIEDLGMYSSQRVLELA.EDPVSFGASEILMDGMAEGLVDAAVLVCDGAGTVVITRPDVLQAIGAHMTGLIKTEPIAE..IQDG..LEQKGCILIDRH-ATIDQIRGFVTAIDAGFERVAVTLAGsmSSDA..RDLRAIGA................RSGRRPFILAVHTTGI.SSDEAAALA.ETCDIIWSCASRAVREVVGER......AVLQIGVSIPVFAMTQEGKRLVLNRA-l...
A0A162FM61_9EURY/7-261               ...................................................................HIIEAMGKT..KVVIKDG..KVVEVG..EPKINYCPLFHK.RRGV.EQIDKKAVKENMEY.RMEKFGMCTPNREIEMN.-DFLSFGISEIISTLLEEKIIDCSIMVCDGAGTVIVNDPNKAQGIGGRVSGYVKTSPILE..VIEK..IKPEN--ILDPENATINQLEGAKIAIKKGFKNIVVTITN..SDDA..KELRKLEK...............eSENINIYLFSVHSTGV.NLDESKELI.KHCDVLTGCASKTIRQNGDEK......ALIKVGESIPIFGTTEIGKKFIEKRL-e...
A0A1D3L1X7_9EURY/14-268              ...................................................................HIIEALGRT..RVVVRDG..KVVEVG..EPKINYCPIFDK.NRGI.KEITSEAVQKNIEF.RIKDFGMCTPERKLRMK.-DFLSFGVSETLSTLLDENMIDCAVIVSEGCGTVILTDPEFVQGMAGRISAFISTTPITK..IIET..IGPEN--VLNPETAEINQIKGVLKAIDMGYRNIAVSVVL..PEDA..KKLRGIEK...............eKEDVNIYIFAAHVTEM.SEEDAKAMF.NTADVITSCASKYINEVGKDR......EIFKVGASVPIFGPTEAGEKFLKTRL-e...
Q8TNP5_METAC/3-256                   ...................................................................HIMELLGKT..RVVVKDG..KVIEVG..EPEVDWCPLFAK.IRGI.KKITPEEVKKNMEF.RISDFGMFTEKRRLELE.-DFVGFGASEVMMTGLSRGLLDTTVTACDGAGTVISNNPTLVQGMGGRMSGLVETEPIDG..IINR..ITECGGIVLDPSTAKMDPVAGVKKAAELGYKKIAVTAAF..AETA..KELRKLEA................ELGLDLIVIGVHVTGL.NREEAQVLV.ENSDIVTSCASKPIRDLVK--......PIAQVGTAVPLFALTQKGKELVIERAK....
#=GC seq_cons                        ...................................................................HlhEslG+s..RVllccG..KVlEVG..EPhlcaCPLacK.h+GI.cclopEsl+cNlEa.RIc-FGMhTspRplchc..saVuFGsSElh.ouLcpGhlDssVhsCDGAGTVlsssPplVQGlGGRhSGLlcTsPIsc..lIcp..lpccss.VLDPpsApIDQltGlcpAhchGY++IAVTlss..spsA..cplRclct..................shclhIhuVHsTGl.sc--Actlh.chsDllTuCAS+tlR-hsttc......slhQsGsulPlFAlTppGKclllpRh.....
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