#=GF ID   DUF2208
#=GF AC   PF09973.13
#=GF DE   Predicted membrane protein (DUF2208)
#=GF AU   COGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   COGs (COG4920)
#=GF GA   24.30 24.30;
#=GF TC   24.30 24.30;
#=GF NC   24.10 23.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR009198;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This domain, found in various hypothetical archaeal proteins,
#=GF CC   has no known function.
#=GF SQ   41
#=GS I0A1Q2_FERFK/9-243        AC I0A1Q2.1
#=GS G4RKP1_THETK/6-234        AC G4RKP1.1
#=GS A0A031LMJ7_9CREN/12-239   AC A0A031LMJ7.1
#=GS S5Z892_9CREN/7-242        AC S5Z892.1
#=GS D9PZE4_ACIS3/9-254        AC D9PZE4.1
#=GS A4YCR9_METS5/12-239       AC A4YCR9.1
#=GS D5U2Y2_THEAM/13-237       AC D5U2Y2.1
#=GS A0A0F7FIU4_9CREN/7-240    AC A0A0F7FIU4.1
#=GS B8D618_DESA1/12-235       AC B8D618.1
#=GS A0A2U9IEY3_9CREN/12-239   AC A0A2U9IEY3.1
#=GS A0A348B187_9CREN/11-245   AC A0A348B187.1
#=GS Q975M9_SULTO/15-242       AC Q975M9.1
#=GS I3TD29_THEC1/9-232        AC I3TD29.1
#=GS A8MD02_CALMQ/11-265       AC A8MD02.1
#=GS A0A830GUP1_9CREN/12-276   AC A0A830GUP1.1
#=GS G0EDU1_PYRF1/1-225        AC G0EDU1.1
#=GS E1QQ69_VULDI/14-281       AC E1QQ69.1
#=GS A0A5J6SN50_9BACI/52-163   AC A0A5J6SN50.1
#=GS Q980B2_SACS2/12-239       AC Q980B2.1
#=GS A1RYG7_THEPD/7-241        AC A1RYG7.1
#=GS F4B7K4_ACIHW/12-240       AC F4B7K4.1
#=GS A0A0U2MAI2_9CREN/9-221    AC A0A0U2MAI2.1
#=GS Q8ZWM9_PYRAE/2-222        AC Q8ZWM9.1
#=GS A0A2T9WVF6_9CREN/9-255    AC A0A2T9WVF6.1
#=GS Q4JAI8_SULAC/14-241       AC Q4JAI8.1
#=GS L0AC98_CALLD/10-244       AC L0AC98.1
#=GS A0A1H7L648_9FLAO/6-113    AC A0A1H7L648.1
#=GS A0A2T9WVT5_9CREN/13-240   AC A0A2T9WVT5.1
#=GS A8AAZ6_IGNH4/9-221        AC A8AAZ6.1
#=GS E0SP79_IGNAA/6-225        AC E0SP79.1
#=GS A0A2R4ZM37_9CREN/5-241    AC A0A2R4ZM37.1
#=GS Q9Y950_AERPE/8-243        AC Q9Y950.1
#=GS A0A650CMG7_9CREN/15-242   AC A0A650CMG7.1
#=GS A0A7L9FI70_9CREN/7-240    AC A0A7L9FI70.1
#=GS A3DN60_STAMF/9-232        AC A3DN60.1
#=GS A0A510DVE2_9CREN/14-243   AC A0A510DVE2.1
#=GS A0A133VP92_9EURY/121-279  AC A0A133VP92.1
#=GS A2BLU5_HYPBU/6-232        AC A2BLU5.1
#=GS W7KQA6_9CREN/12-238       AC W7KQA6.1
#=GS H2C6X5_9CREN/12-239       AC H2C6X5.1
#=GS A0A0V8RW15_PYROC/6-232    AC A0A0V8RW15.1
I0A1Q2_FERFK/9-243                   .........................r-QIAIGQASIIIFSIAAGFLg..rsGAVYWL..FIILYFILYMIIMTKFGQPK...-LPNTAKADLISKGKVLFE...ENKAMEVASTDRQYVV.EMQDQLKMLQ.FTTLF.....SFLVLIYFFI..---AI...GP.....VTSLIAPKF................SNEKIGYSVSYFILFEGSFLLSIFGQYLSvr..nySRSGKKFV..TINMPR..TFFVTSEGIVLKg...mmSSTGLKFPLT..-AYKIVLNEERKFVELVNETQ..........KAI.N.KIRLY..TKSPNKLYEVIS--n.................................................
G4RKP1_THETK/6-234                   .........................l-RLLITVGTIFGYAAVMAVL....gPQYLWL..VGLLYIGSVFAITTALGIRA...YRRGSLQAREIVKGKLLFEi.nEKDTNKALEKDREFQE.EMRKLNRVFM.IYFMAf..piMLIGIWLFPA..FQSTI...VP.....AVSASLEQS................LGRFLATYFGYVALFAAFTAIFSPLYYFT......F---RPIQ..FPIIAT..DVKIYDTGIVIN......KNTGLKAPIH..-VQEYKYIPERKFIELKIGNQ..........---.-.LYRIY..YKDIEEVHKTLSKM..................................................
A0A031LMJ7_9CREN/12-239              ..........................KFLLLTQVWLVAISIILSYF.....PQYYIE..ALAIYFVVFLGISFSIQYKTn.pMFRDRKLLAEVANSRVIYE...EKDVTKIVQADAELQR.EYMEAAKKNL.SMMGI.....YVVYIIALFI..AYGYL...VR.....FADSFPGTY................-----GRLLVYLVYFEALYLVGYFMF---......RKILRPTM..MSVMAP.tSYSVTEKGIYSK......KGYSTFLHAKhlVDSKIDVNKEKHYVEIDSTST..........KLP.Y.KIRLY..APDVDRLMEYIERV..................................................
S5Z892_9CREN/7-242                   .........................l-QYLIGLVLLVVFAFLNANF.....PQYTSW..IFLLYFIALMSIMFVLMGKQ...TQTLLKDLDEIKKGETLYKs.nMEEVVKLRERDLQNTQpELMGQFKATL.VPFFS.....LLVFIFVFYIpqVRDFF...FQ.....-AGRMFAPV................-DTKMASFFEYLFLYGFFYVISLISGLYT......RRLQAKTG..TLVIAT..NYVVTSKGVIVD......ERMPIKFPLK..--GNIVVDSRRKFVELETVQQvm......gsTVK.Q.RIRLY..ASEPSKLANLLKT-y.................................................
D9PZE4_ACIS3/9-254                   ..........................RMVALNQLYILIYSALAAVIg...iNVYLFL..LIFVFIAISMFVQSILMSSG...LNEKSSYVAEVLSGKRLFH...EDNTRAIQSKDTLIYV.DLQEQTKFSL.YTTLG.....ILIGLAYFFV..LWRYV...PD.....LAAYLSLELfgrqi......kdvgiEYLRLLLFIAFLLYFEGYFVINQGIMMWS......LSRIKKLP..ALNVPT..SYIVTDKGIVIKg...liTTKGIRFPLP..PDIEVVLNKDRRFVELTRQGK..........RTV.T.RLRLY..TKNPEKLYEIIRKV..................................................
A4YCR9_METS5/12-239                  ..........................KFALISQTYLVVISIVLGFY.....PKYFLE..AFISYFIIIMAITFSMTYKSn.pMLRDRKLMMEVANSGTLYE...EKNANDLVMKDEEYQR.EYMQFAKKNM.TMLFS.....YLIYIVVLFF..VYSYV...SK.....IATSQTDPY................-----YRLAVYLVYFEIIYLFGFFVY---......RRLFKPSM..MSTMAP.lSYKVTEKGVIGS......GGMSVFLHAKhlLNSNFVVNREKKYVEIDSTEA..........KYP.Y.KIRLY..AKDIDKLLDMLERV..................................................
D5U2Y2_THEAM/13-237                  .........................t-MWAVQALSMVLFALVSAVV.....PGYAFA..FFLVYFIVFMAVMFKLTSKG...----MKPPPRSELGSPVFK...ESNPVNAMMYDKYLNA.ELKKQMTMMM.LNFML.....LFFVFILWSI..YQAYI...GP.....LIVSIIGEY...............tGDEVLLRFTYFLGMYVFFFGVMQGLRYLL......FRGSDMQT..FLFARI..GFEVYRKGVMLD......NRQFIAFNEN..--ICFEPNPDRKFVELRSRSN..........-KS.M.RIRLY..TLETGKLIDKLR--ea................................................
A0A0F7FIU4_9CREN/7-240               .........................l-QYLLGFVLMVLFSYMNAHY.....PDKTWL..FFTLYLLVFMGIIFFVTGRQ...AQNIFRDLEEVKKGEIIYQa.dPDQSLKLREKDMEKTQgELAAQFKVSL.IPMLT.....MILFLMVFYIpsFRQFF...QN.....IGNTLT---................QDQKMAMFYSFLAMYGSFYLISMITGLYT......RRVQSKTG..TLTIAT..KYTITSRGIIVD......DRLPIKFPLK..--GSIGTDNKRKFVEITLIQQvm......gsQVK.Q.RIRLY..TPEPSKLANLLK--e.................................................
B8D618_DESA1/12-235                  .........................t-MIVMQAVSILLFALVSAVI.....PNYAFI..IFLLYFLVFMFLAMRATTRT...----MKIPPRNELGSPLFK...ELNALQVMLSDKIFQA.EMNRQMKLMF.INLGL.....VFLLFILLPV..YNNYI...WP.....FISGALGLT................GESILVNFIRFLGLYLFFLGVMQGMRYML.....iRGQSSTPP..VIPA-R..VFAVYKKGVVLD......ERQFVKFTED..--ICFRVDHDRKFVELVNTRG..........-NT.V.LTRLY..TLEVGKLTEKLR--ea................................................
A0A2U9IEY3_9CREN/12-239              ..........................KYVLLSQVYLIVISVVLTYY.....PQYFIE..AIVTYFIVMMGVMFYSMSKSn.pMFRDRKLLYEINNSRLLYE...EKNASELINKDKEYTE.EYTKYAKKSF.SMLGI.....YLVYMIVLYF..LYTYI...SK.....IAISQASSF................-----DRLLVYLIYFEVIYLFAFFVF---......RKIVKPAM..LNIMAP.fSYKITEKGIVGS......GGMSTFLHARhlLDANISVNREKHYVEIDSAQA..........KLP.Y.KLRLY..SSDVDKVLDYIER-i.................................................
A0A348B187_9CREN/11-245              .........................k-YLAVSQVLLVVLAIANSFL.....PKYFFL..FYILYLIGTFAFIGIFTYRTn.pMIRDRSLMKEVMSSRSLHE...EKDVQQLIMNDREYVK.ELTAQSSKML.KYMLF.....LLIYTVAVIL.vYDDVL...IK.....VINSPAFK-................-ANDIYRFVIYVIYFEALFGISFIMS---......RRVFRMGN..INKVAP.nSYKITEKGVVGN......GFPSVTIHGVhlADAEIRVNPENKYVEIVPSDAs.......kkSVP.Y.TVRLY..SNDVNKVKELLERV..................................................
Q975M9_SULTO/15-242                  ..........................KMILISQALMILMSFVLSLY.....PQYFLP..VYILYIIVILGITSVMTMRSn.pILSERKYLSDISNSRTLFE...EKKAGELVQKDEEYMK.KMQEFAMASF.KSFMY.....MIIYIIAIFV..FYDEV...LL.....KIVGSISGY................-----ERLLVYIIYFEALFLFNMFVY---......RRLVKFQA..MEVMAP.qSYKITEKGILST......DKSGIFLHSRhlVNAEIKENREKRYIEIHSQTS..........KLP.Y.RIRLY..TTEIDRLLEVLDRV..................................................
I3TD29_THEC1/9-232                   .........................v-SILINAVSIIVIALLTTLL.....PAYSLL..IFFVFYMFVLFIVYRFTMKT...----GKMPPPSELGTPLYK...ESNAMKVAVSDPGLNK.DLGQQFKFLM.VTIAI.....SILAIFLYSL..YNGLA...GV.....ELVSLLLTV...............tGSRLLSNFLNYVTMYAFIFVILYSLRWAV.....tRKMTYVNL..IIPY--..SFAVYRKGIVIN......NKNFIALDHN..--LCLIFNKQRRFIELLDPRS..........-KS.S.RIRLY..TETPTTLYERL---vev...............................................
A8MD02_CALMQ/11-265                  ....tyvlwvatpvafaaffawgqvi--------------------.....KNYWMPigLFIAYFILIFGISAYAGYKS...YSRNRREGEQYRRRQALSRl.tGDDIKKAMERDYELPK.EYSALSKKMF.LNLGI.....MIVLLIAVLL..VYSTL...FN.....KIAEVISALlgst.......smaqsTVEFLRYFITYLIMFGIWFAVFYVVARYTglpylsQNTSMMQN..MPYIPT.kSITFYKDAVIFD......DLYVLKAPLD..-ADSVMVDEKRRFVEIVLKKPm........sNLP.YrRLRIY..TRDPRGVWE-----kyvsk.............................................
A0A830GUP1_9CREN/12-276              ylfwvaapiafaaaaawgevahnswl--------------------.....---SIG..VFVGYLVIVFGAMIAMSYRT...YRSNAAEIEKYKKQSALGKl.dPDEIRKAMERDSELQK.EYSQMSKGMF.KNMFIllallLVIIFIYPTL..LSTVV...NK.....FISAIITDYaag.........latfYRSFLSYFFGYLVLFGVWFLVFYVLSRALkl.pfaGQSANPMG..NLPMIPskGVIFYRDAFILD......GSYIMRTPMA..-VKKVLINERRRFVEIELEQGpkdkkrnpmtMPY.Q.RIRLY..TKSPRELWNK----vlsky.............................................
G0EDU1_PYRF1/1-225                   ..........................----MGQVFILMLAFILAFF.....PHLYIF..AIFGYIALMIVVQMLVQSRA...---SRSEREEVLRSRIIYR...EDKLEEIIASDESLVE.EYSRIVKTTT.LPSLL....sIPVIILLFWL..LPGVY...HD.....IVTKQFG--................LEEHMARFVTWLLVFESTFAASMIARLTA......MRVYGRPT..MLMIAR..GFEVRERGLVLKs...glRDTIIPFPLD.tERYELHIDENRRFVELRDRKS..........--G.V.RIRLY..TTKPRRVYELITRL..................................................
E1QQ69_VULDI/14-281                  ....................ryvwpi-------AFVLAFAIVGAWGnvaheTFVTWI..IVIAYLVIFFGIVIAIGIRStrvRFREIEEYMKSTKSGAVEKl.tRDDFIKAMEKDPEYVQ.ETNRFVKSQM.KNMII.....LMVVLIGLLL..LYTYV...LSgpfitLAKYISSTVnigyylkpwftqtiqeANLFYAYFIDYLIYFGVFFVLMYVIFRIM......RMPFMTTN..-VQITD.yPYTVTKELIIFRdamlidGMYLLKSPIQ..-VKQIVINEKRRFIEFQLSKPl........sGLPyT.KIRIY..HKSPRDLWD-----kamk..............................................
A0A5J6SN50_9BACI/52-163              .......................tgl--------------------.....------..----YNVVALFFATLNSWYT...----HYQSKKRNNGRIIMK...EIVIPEMIHDDERESE.ITGKSAKAAFsIMFVF.....SFILMASFSL..VPYAL...NN.....PLSYAVFAI................ASLPIVGFIAYFIVSKVLY----------......--------..------..------------......----------..---------------------..........---.-.-----..--------------s.................................................
Q980B2_SACS2/12-239                  ..........................KFVLLSQVMMILFSLVLSFF.....PKYFIE..FYILYILVYLGITSVIMMRSn.pLLRERRSLGEIANARTLYE...EKKASELVNQDEEYLK.ETTEVMKKNF.SSMGI.....MFLYMIILIL..VYNYV...II.....RFVTNIDNT................----LYKFGFFVLYFELLYGVSFLMN---......RRVLKFQT..NIPMAP.tSYKITEKGIIAT......DRSGVFLPSKylIDAQISQNRDKKYIEIRSSSK..........-FP.F.QVRLY..SQDIDKVSELIERV..................................................
A1RYG7_THEPD/7-241                   .........................l-QYLLGLVLMVLFAYMNANY.....PDKTWL..FFILYFTAFMVIMMVVTGRH...ARSVLRDLEEVKSGEILYSs.kPDEVLKLREKDFQLTQpELMAQFKASM.IPLLS.....LVVFILVFYIpgFREFF...TG.....LGKSMA---................LDEKTANFLSFLALYGFFYAFSLATGLYA......RRLQSKTG..SLIIAT..SYTVTSKGIIVD......ERTPVKFPWK..--GDIIVDSRRKFVQLNITQQim......gtSIT.Q.KIRLY..NPEPSKLANILKSY..................................................
F4B7K4_ACIHW/12-240                  ..........................KFLLFTQAWLIIISIVLTYY.....PQYYFE..VIILYIIVIFGFTFFMTYKSn.pVFRDRKLLYEIVNSRTIYE...EKDVTKLIMADQEYQK.QYMDSIKRNF.RMLGF.....YIVYLAILFF..AYQYI...IK.....FADSQTLTY................------RLLVYLVYFEALFGIGFFVS---......RKILAPSMsnMAPMAL.pSYKITEKGIVSG......KGYSVFLHAKylLNSEITINREKHYIEIDSTKQ..........KLP.Y.KVRLY..SQDIDKVLDYIERV..................................................
A0A0U2MAI2_9CREN/9-221               .........................k-AMLLSQASMLTFATIMSFF.....PQYYGF..LLVIYFILMLVIMYKYFGKH...----LKKAMERPKGKVHY-...EENSKELLETDPEMER.ILKGQMSQSL.FSSLP.....IMVLLLFGFT..LWPTI...TH.....----IPN--................---PVYRFAAIVAYFEGYTVLNYFLNKH-......--AMKKMA..EIPKPI.tSYKVTEGGIQIK......PFGNIPFPLK..-DYEIKVVEESKAVDLVSKKP..........-GV.P.SYRLY..SKNPKRLAELLLK-l.................................................
Q8ZWM9_PYRAE/2-222                   .........................r-RVLITLLSILGFSAVLTFF.....PAEFFT..VLILYFVFFFGLSIIMGLRS...YRKGVVAAQEISRGRPLIEi.dEKEVNKLLEKDKELIN.EYKRFARASF.MPLLT.....LPIFILLATF..LFPTL...PP.....LAESGLGPV................VGREAARFLSYVVVFGIFAVISMATF---......----RPPV..APRIVR..NLKVYEAGLVID......KSLGLKAPIE..-VTDYKINEERKFVEFKLNNQ..........---.-.IFRIY..YKDIKELDSILSKL..................................................
A0A2T9WVF6_9CREN/9-255               ........................rl--VALNQLYILIYSVLAAIIg...vNIYLFL..LVFVFIAISMIVQSVLTSSN...LNEKGSYVPEILSGKRLFH...EDNTRAIQTRDQLIYL.DLQEQTKFSL.YTTFG.....VLIGLAYFFA..LWKYI...PD.....LASFIALKLygssa.....lkslpfWEARLALFLAFLAYFEGYFIINQGIMMWA......LSRVKKLP..ALNIPT..SYIVTDKGVVIKg...lvTTKGVRFPLP..PDVRLNLDKNRRFVELVRDGR..........RTV.T.KLRLY..TRNPEKLYDILRRV..................................................
Q4JAI8_SULAC/14-241                  ..........................KMILLSQTSIVIISFVLSLY.....SQYFLP..VYIAYLIIYFIIMTTIMARSn.pMLSERKYLSEIVNARTILE...EKKAGELIQNDEEYIK.KFQAITSANL.KSFGI.....MFVYLIVILI..FYNFV...VL.....RYVSSVTQI................-----QKLIVFLVYSEALFLFGMFVN---......RRIMRVQM..MEVMAP.fTYKITEKGIVST......DRSAVFLHSRhlVNASIVENRDKKYVEISPTTL..........KLP.Y.KLRLY..SNDIDRILDAINRV..................................................
L0AC98_CALLD/10-244                  ..........................KSTLLNQVYIIIYSILAAIIg...vNYLLFI..LVIVFVIISMFLQSYLSGSP...-LGKNIKPQEVLQGKRLYH...EPETRSIQMKDKQVMV.DFQEQSRFTM.YTTIG.....MFIGLIYFFV..LFRYV...PD.....LANFLKLYI................TDYRIDLFLAFLIYFEGYFAITMLNTMWA......VSRIKKLP..MVNVPS..QYTITDKGIVIKg...lvTTKGIAFPLP..NETNVNLNEERRFVEIIKEGK..........RTI.T.KLRFY..SKNPKRLYEIIKKY..................................................
A0A1H7L648_9FLAO/6-113               ......qnihntlteynpiyathpel--------------------.....------..--------------------...-------------------...EDNIMDIVKKQKNYKE.ILMKTRHKVK.AGLIV....sVILLLIYIIL..TYTDLlnsID.....QNEESIKLF................YPSILATIVVILVYFQGIFGISIL-----......--------..------..------------......----------..---------------------..........---.-.-----..--------------kke...............................................
A0A2T9WVT5_9CREN/13-240              ..........................KMIVISQAAMLALSAVLSFY.....PEYFLA..FYILYIFIIMGVSLYMAQKSn.pLMSQRKYLSEVVKAPSIFE...ERKAMEVAMRDDEYQA.MLRDYTSQTL.RSLGI.....MFLYMLFLIA..FYYTV...FV.....RITENYVG-................----LYRFLAYVTYFEALFLFNFFVY---......RRIVKFRM..MEVVAP.sNYKITIKGIAST......DVTGLVLYFKhlSDARITVNPDKSYIEIDSQSS..........KLP.Y.RVRLY..SKDLQRLKEAVEKL..................................................
A8AAZ6_IGNH4/9-221                   ..........................KTLLISLLSTTAFAAVLSFF.....PQYYVY..LILAYFVIMPIIMVKFMSKQ...----IKEMRAPGSGKTLM-...EEDAKELFDKDPQGDI.ILKAQMKQNA.LGMVP.....FLILIALAFT..LWPAI...LH.....---------................LEEPWLRFIAIFAYFESYTLLNYFLNKYN......LKNMKKVP..RPVY--..QYKVTDKGIQIK......PFGGITFPLK..-GYSIKLVKESSAVDLVSKED..........-GK.P.SYRLY..AKEPERLYDVLRRL..................................................
E0SP79_IGNAA/6-225                   ..................tmalyiii--------PLIFFATVSTFV....pPNWTFV..VFLLYTIVFLSIASIIPQLR...----ARKKASEAGGNVILRs.nEQEVLKLITKDTQLSD.EIKSQLTSTM.ILFIA....pFIIWYIVSIT..IYPIL...IP.....QNSGNIDLM................-----QRFLRNLIFYGILMGIFQGL----......RMVTMPKK..MIIAIT..KYEIRNVGLKL-......GSIFIPFPID.lKRYSISVDHKRCFVEIFDRSS..........--R.Q.AFRLY..ATDPQKIISIIERY..................................................
A0A2R4ZM37_9CREN/5-241               ........................as--YIVSQVLAVLYALALTFL....pGDLYWI..VITLFFISYMAIMVAINVRRm.rISATSPDAQFVSSGRQIVRm.dSKKALEIMQNDTDLNY.ELREQAKVML.MPMLS.....LPIVFAIYYI..YTAHV...TP.....LYITHDD--................---ALIRFLGNLVMFEIFFLIPMAINKLM......R-KGKPTV..FVQPVM..NYLITDRGIQG-......AGILIKFPIE.dHSIDIRCNKSRKFLELVREQNnp.....msgRMI.M.IQRLYmdSKELEKAIDALKKY..................................................
Q9Y950_AERPE/8-243                   .........................n-RILMSQAFIILYSLLASILg..rsWKTFAV..IIILFIVLSIVMSRRSKGP-...-LGVKASPADIESARRLYE...EKGARELQMKDEGLAS.DLQEQSKALM.SMNLI.....MIVGLAYFIL..FWRFI...DP.....LYEFVAANV...............tSNELLAHFLAFLAYFEGYFVVNTVSAYVV......SKRSGPMI..TINMPT..EYTVSEKGIVYKg...liSKTAIPFPLP..EGVRVSLNERRKFVEIRKVNT..........KTD.F.RLRLY..ARNPKRLYTIIERY..................................................
A0A650CMG7_9CREN/15-242              ..........................KMILISQVLMILMSFVLSLY.....PQYFLP..VYILYILVIMGISSVMMARSn.pMLAERKYMGEIYKSNTLFE...EKNAGSLIQKDMEYVQ.KMQQLAVANF.KSFGI.....MILYIIIIFL..FYDYV...LL.....KIVGSVTQY................-----EKLAIYLIYFEALYLFNMFVY---......RRLIKIQM..MDAMAP.sSYKVTEKGILST......DKSGVFLHSRhlVNAEIIENREKKYVEIDSKTS..........KLP.Y.KIRLY..TNDIDRLLEVLNRV..................................................
A0A7L9FI70_9CREN/7-240               .........................v-QYLLGLVLMVLFAYMNANY.....PDKTWL..FFMLYFLAFMGIIFLVTGRQ...ARSMLRDLEEVKGGEKVFEa.dPQEVLKLRERDMERTRsELAAQAKVSL.VPLAS.....MIVFILIVSVpsLRGFF...DS.....VGHMLA---................QDQKTATFYSFLAMYGTFYAFSLVTGLYT......RRLQAKTG..ALRIAT..KYLVTTKGIVVD......DSIPVKFPIK..--GTVVTDSRRKFVEVHLVQTym......gtTVK.Q.RIRLY..TEEPSKLAGMLK--q.................................................
A3DN60_STAMF/9-232                   .........................t-SLLISQVSILLISLVTAFI.....PQYYIY..IFILYFIIIMAFMFRSTRKM...----SKIPPKKELGSPLFK...ENNAIKIAMLDKLLTA.ELKKQFTASM.SLLLL.....TFLVFIIFPL..YRQFV...FV.....PVHELLSSI...............iGNPVLVNFLDFFIMYEFVFGILSILRFFI.....mGKMSGVNI..MLPQ--..NFILYKKGIIAN......DRFFIELTSD..--LCYKYDLKRHFVELRSRTN..........-KN.F.RVRLY..TDSTSDLLNKIKD-l.................................................
A0A510DVE2_9CREN/14-243              .........................r-FIALSQFSVIFISALISFF.....PQYYIL..GYVIYLAISLSLTSLLTFRSn.pMLRERKYMGEIMRSKTIYE...EKNAKEVMNKDEEYMK.IYKQMLKRNG.YSMLY.....LVGYLVVVLV..IYDVV...FD.....RYRTMFG--................-SNHLDLFLAFFLSLDAVVLANIFIS---......RKVMKGAT..SQIMAP.qTYRITEKGVIAS......DATGVFLHSRhlPSSDINVNREKRYVEIKSNTI..........KLP.Y.DIRLY..TRDIDKLLDVLERV..................................................
A0A133VP92_9EURY/121-279             ......................igls------------------FLy...eHAVFVI..FGISFFLAILVNTISRTVVNweeV--NEAKRKQSELQEDLKKarrEKDMKKVHKLQNEQQK.FMQEHMGTMM.SPMKT.....MLIIFIPFII..IFNVM...SG.....IYSG-----................-----------------------------......--------..------..------------......----------..---------------------..........---.-.-----..--------------wvvawlpfnllwpdiglpllsrffrgtvasmgffswylltyfglsqiwrk
A2BLU5_HYPBU/6-232                   .........................s-MMLVSQVYFVILAMVLAIA.....PQYYML..VFLIYFVAIMAFSMYTSKRR...MKGARIPREEVEAARQLFR...EDNSFQIAVEDEELVR.QLTGQAKTAI.MTFLF.....LPIYITIFEL..VRRNY...SS.....LISALQGAG................LSETLAGFVVWFAAFETMFLISMVS----......RRVVRQAK..QPPMVP.rGFVVTEKGILLKg....sMGGVIGFPLP..EGTEVKLDEKRNCVEIVFPGG..........---.S.RLRLY..TRKARRVYELIQRL..................................................
W7KQA6_9CREN/12-238                  ..........................KYALISQVYLVALSFVLTYR.....PQYFIE..VVALYFVFFTGLTFYMMSKSn.pLLRDRKLLYEISSSRVLYE...EKNVSDIINKDKEYVE.EYTKFAKRSF.SMLGI.....YLVYLVAIYF..LYSNV...TK.....IADAQVALY................------RLLVYLVYFEALYLFAFFVF---......RRIVRPAS..LSVMAP.vSYKITEKGIMSS......GGMSMFLHAKhlLNSNIVVNKEKRFVEIDSTQA..........KMP.Y.KVRLY..SNDVDKVLDFIERV..................................................
H2C6X5_9CREN/12-239                  .........................k-FAAISQGYLIVISIILGFY.....PKYFLE..AFISYFIIIMAITFSMTYKSn.pMLRDRKLMLEVANSGTLYE...EKNANELITKDQDYQR.EYMQFAKKNM.MMLFS.....YLIYIVVLFF..VYNYV...SK.....LATAQTDPY................-----YRLGVYLAYFEVIYLFGFFVY---......RRLFRPSM..MSTMAP.lSYKVTEKGIIGS......GGMSVFLHAKhlLNSNMVLNREKKYVEIDSTSA..........KYP.Y.KIRLY..AKDVDKLVEMLERV..................................................
A0A0V8RW15_PYROC/6-232               .........................a-MMLIGQLYLAVLSLVIAIA.....PHYYWL..VFIVYIVAIMALGMYSARGV...--SGKVPREEVVKARTLMK...EDKAFEIAMEDEDLIR.LYAGQAKSMM.IMLLL.....LPIYYILFRA..AA-AY...HD.....EAVANLNSI...............gIHGVLAGFVFWLLVFEAMFLLSQASRKLM.....vG---GGVK..QPPLVP.hGFRVTEKGIVMKg....sMGQVIGFPLP..EGSEVKLNESKNYVEIRYPKG..........---.S.RVRLY..TRKARKLYEYIVRY..................................................
#=GC seq_cons                        ............................hllstshhllhuhlhuhh.....PpYahh..hhllYhllhhulhhhhsh+s...h.ttpc.htEltpucsLac...EcsshclhpcDp-h.p.-hpptsKtsh.hshhh.....hllhllhhhl..hhshl...hs.....hhss.hs.h....................htpFlsaLlhF-shallshhhh.........p+hhphth..h.shss..sYplTcKGIlhp......sthslhhshc...stplhlscc++aVElpppps...........hs...+lRLY..op-sc+Lh-hlc+h..................................................
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