#=GF ID DUF2250
#=GF AC PF10007.13
#=GF DE Uncharacterized protein conserved in archaea (DUF2250)
#=GF AU COGs;
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Sammut SJ;0000-0003-4472-904X
#=GF SE COGs (COG4344)
#=GF GA 24.40 24.40;
#=GF TC 24.40 24.40;
#=GF NC 24.30 24.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF CL CL0123
#=GF DR INTERPRO; IPR019254;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC Members of this family of hypothetical archaeal proteins have no
#=GF CC known function.
#=GF SQ 119
#=GS A0A4D6HH51_9EURY/193-285 AC A0A4D6HH51.1
#=GS A0A256HCY6_9EURY/28-91 AC A0A256HCY6.1
#=GS H2C915_9CREN/110-202 AC H2C915.1
#=GS A0A1B9F7Y8_9DELT/5-89 AC A0A1B9F7Y8.1
#=GS A0A5S4ZPE9_9FIRM/136-226 AC A0A5S4ZPE9.1
#=GS C5CEI2_KOSOT/7-92 AC C5CEI2.1
#=GS H2C915_9CREN/8-100 AC H2C915.1
#=GS D3TC09_ACIB4/1-90 AC D3TC09.1
#=GS A0A6P1ZH37_9DELT/2-93 AC A0A6P1ZH37.1
#=GS L0JY40_9EURY/193-277 AC L0JY40.1
#=GS A0A8J8CEQ5_9EURY/193-285 AC A0A8J8CEQ5.1
#=GS F0S2Q3_DESTD/7-97 AC F0S2Q3.1
#=GS L0AIU2_NATGS/94-186 AC L0AIU2.1
#=GS A0A6A9T1Z5_9EURY/1-42 AC A0A6A9T1Z5.1
#=GS A0A1Q1FPF6_9EURY/193-285 AC A0A1Q1FPF6.1
#=GS A0A256KMX0_9EURY/31-96 AC A0A256KMX0.1
#=GS A0A2T9X0L7_9CREN/102-194 AC A0A2T9X0L7.1
#=GS A0A1H6J9N4_9EURY/6-68 AC A0A1H6J9N4.1
#=GS A0A6G2HD06_9EURY/21-90 AC A0A6G2HD06.1
#=GS Q96YS5_SULTO/9-101 AC Q96YS5.1
#=GS A0A2T9WVC2_9CREN/6-98 AC A0A2T9WVC2.1
#=GS G0EFH4_PYRF1/123-214 AC G0EFH4.1
#=GS A0A031LMH1_9CREN/111-203 AC A0A031LMH1.1
#=GS A0A1Q1FH04_9EURY/193-285 AC A0A1Q1FH04.1
#=GS C8VZV7_DESAS/117-207 AC C8VZV7.1
#=GS N0BK51_9EURY/102-194 AC N0BK51.1
#=GS C9R7Q1_AMMDK/3-94 AC C9R7Q1.1
#=GS Q9HLB2_THEAC/8-100 AC Q9HLB2.1
#=GS A0A6F8ZDH0_9FIRM/18-106 AC A0A6F8ZDH0.1
#=GS Q5JG76_THEKO/14-106 AC Q5JG76.1
#=GS T0LX01_9ARCH/11-103 AC T0LX01.1
#=GS Q6KZK1_PICTO/7-99 AC Q6KZK1.1
#=GS V5A3Z8_9ARCH/193-285 AC V5A3Z8.1
#=GS D9PZR9_ACIS3/107-199 AC D9PZR9.1
#=GS N0BK51_9EURY/2-94 AC N0BK51.1
#=GS A0A238WVB1_HALVU/22-89 AC A0A238WVB1.1
#=GS A0A2U9IF42_9CREN/111-203 AC A0A2U9IF42.1
#=GS A0A8J8CEQ5_9EURY/94-186 AC A0A8J8CEQ5.1
#=GS A0A2T9X0L7_9CREN/1-92 AC A0A2T9X0L7.1
#=GS A4YIE5_METS5/9-101 AC A4YIE5.1
#=GS F4B6B1_ACIHW/111-203 AC F4B6B1.1
#=GS A0A4D6HH51_9EURY/94-186 AC A0A4D6HH51.1
#=GS A0A256IAL3_9EURY/31-96 AC A0A256IAL3.1
#=GS A0A6A9T5B5_9EURY/30-90 AC A0A6A9T5B5.1
#=GS A0A1I6DYB4_9FIRM/13-98 AC A0A1I6DYB4.1
#=GS A0A0Q0RY96_9ARCH/7-99 AC A0A0Q0RY96.1
#=GS A0A031LMH1_9CREN/9-101 AC A0A031LMH1.1
#=GS F6DSP3_DESRL/113-212 AC F6DSP3.1
#=GS A0A6F8ZJK7_9FIRM/15-120 AC A0A6F8ZJK7.1
#=GS T0M289_9ARCH/11-103 AC T0M289.1
#=GS A0A830GTZ9_9CREN/7-99 AC A0A830GTZ9.1
#=GS F2KN96_ARCVS/106-198 AC F2KN96.1
#=GS R1E4M7_NANST/9-101 AC R1E4M7.1
#=GS A0A496AP79_9BACT/70-162 AC A0A496AP79.1
#=GS W7KLG6_9CREN/10-102 AC W7KLG6.1
#=GS G4RNA2_THETK/15-90 AC G4RNA2.1
#=GS Q97WF9_SACS2/113-205 AC Q97WF9.1
#=GS A0A1X4XWH3_9DELT/1-90 AC A0A1X4XWH3.1
#=GS M0C5A2_9EURY/193-278 AC M0C5A2.1
#=GS G4RM81_THETK/1-93 AC G4RM81.1
#=GS Q96YS5_SULTO/111-203 AC Q96YS5.1
#=GS Q18IX1_HALWD/193-285 AC Q18IX1.1
#=GS F2KN95_ARCVS/5-108 AC F2KN95.1
#=GS A0A1S6J0M0_9FIRM/1-91 AC A0A1S6J0M0.1
#=GS A4YIE5_METS5/111-203 AC A4YIE5.1
#=GS L0ABP7_CALLD/119-211 AC L0ABP7.1
#=GS A0A2C6MER9_9FIRM/4-94 AC A0A2C6MER9.1
#=GS A0A1Q1FPF6_9EURY/94-186 AC A0A1Q1FPF6.1
#=GS A0A510E6J0_9CREN/12-104 AC A0A510E6J0.1
#=GS F8A7Z5_THEID/7-92 AC F8A7Z5.1
#=GS A0A494X1S9_9FIRM/4-93 AC A0A494X1S9.1
#=GS L0AIU2_NATGS/193-278 AC L0AIU2.1
#=GS A0A4U7F8Q0_9EURY/27-95 AC A0A4U7F8Q0.1
#=GS Q4J7U2_SULAC/107-199 AC Q4J7U2.1
#=GS M0C5A2_9EURY/94-186 AC M0C5A2.1
#=GS A0A1I6EF79_9FIRM/5-70 AC A0A1I6EF79.1
#=GS A0A4P2VBS6_9ARCH/120-212 AC A0A4P2VBS6.1
#=GS Q18IX1_HALWD/94-186 AC Q18IX1.1
#=GS M1QI07_9AQUI/9-99 AC M1QI07.1
#=GS A0A179D684_9BACT/7-91 AC A0A179D684.1
#=GS A0A7D5GI44_9EURY/5-72 AC A0A7D5GI44.1
#=GS E1QSW4_VULDI/1-92 AC E1QSW4.1
#=GS Q97WF9_SACS2/11-103 AC Q97WF9.1
#=GS A0A1W1WJH3_SULTA/15-103 AC A0A1W1WJH3.1
#=GS A0A6I7LSY0_9BACT/69-159 AC A0A6I7LSY0.1
#=GS D9PZR9_ACIS3/4-96 AC D9PZR9.1
#=GS V5A3Z8_9ARCH/94-186 AC V5A3Z8.1
#=GS S0ARL8_FERAC/7-99 AC S0ARL8.1
#=GS L0JY40_9EURY/94-186 AC L0JY40.1
#=GS W7KLG6_9CREN/112-204 AC W7KLG6.1
#=GS A0A498GCI9_9EURY/193-285 AC A0A498GCI9.1
#=GS A0A1Q1FH04_9EURY/94-186 AC A0A1Q1FH04.1
#=GS F4B6B1_ACIHW/9-101 AC F4B6B1.1
#=GS A0A1Z5HT67_9THEO/12-98 AC A0A1Z5HT67.1
#=GS A0A1W1WLJ3_SULTA/13-119 AC A0A1W1WLJ3.1
#=GS A0A6G7PYB1_9BACT/5-93 AC A0A6G7PYB1.1
#=GS F2KN96_ARCVS/6-98 AC F2KN96.1
#=GS A0A4Q2WH88_9FIRM/118-208 AC A0A4Q2WH88.1
#=GS V4Y033_9ARCH/22-89 AC V4Y033.1
#=GS D2REQ1_ARCPA/2-90 AC D2REQ1.1
#=GS A0A8J8PAB9_9EURY/193-285 AC A0A8J8PAB9.1
#=GS L0ABP7_CALLD/10-108 AC L0ABP7.1
#=GS Q4J7U2_SULAC/5-97 AC Q4J7U2.1
#=GS A0A348B1X3_9CREN/1-90 AC A0A348B1X3.1
#=GS G0EFH4_PYRF1/5-106 AC G0EFH4.1
#=GS A0A2S3QGS6_9FIRM/3-90 AC A0A2S3QGS6.1
#=GS M0FCV4_9EURY/18-79 AC M0FCV4.1
#=GS A0A510E6J0_9CREN/114-206 AC A0A510E6J0.1
#=GS A0A8J8PAB9_9EURY/94-186 AC A0A8J8PAB9.1
#=GS G0EFH4_PYRF1/224-316 AC G0EFH4.1
#=GS A0A650CRA2_9CREN/112-204 AC A0A650CRA2.1
#=GS A0A4P2VBS6_9ARCH/19-110 AC A0A4P2VBS6.1
#=GS A0A650CRA2_9CREN/10-102 AC A0A650CRA2.1
#=GS A0A2U9IF42_9CREN/9-101 AC A0A2U9IF42.1
#=GS A0A418M0L7_9BACL/3-88 AC A0A418M0L7.1
#=GS A0A348B1X3_9CREN/98-189 AC A0A348B1X3.1
#=GS A0A1Q6DSU4_9EURY/136-229 AC A0A1Q6DSU4.1
#=GS A8M9U9_CALMQ/1-92 AC A8M9U9.1
#=GS A0A498GCI9_9EURY/94-186 AC A0A498GCI9.1
A0A4D6HH51_9EURY/193-285 ...................r-NVLRHLPDGKTLVERLARGG.PD.....YPRMTAE.....E.....L.....EMG...FEYVRHLYRALRQVGLVTEYE.GS.........TI.KAS.E.......R.KLK.......PKDETHRKHTYYVATDHGETALREL............................
A0A256HCY6_9EURY/28-91 .............rvaltrt---------DERVLAYLDDAG.TD.....YPAFVAS.....N.....T.....GLY...ADHVESRLDALEAGGLVERVT.GE.........AV.YR-.-.......-.---.......-------------------------itdy........................
H2C915_9CREN/110-202 ...................i-ELLKNDQKSTKILQLAEELN.AD.....HALTYAK.....L.....I.....RSS...LEEAITLLEKLMRMGLLEEKN.AR.........II.KFR.D.......R.KAK.......PKKETRTHHKYYGLSRLGELVVREM............................
A0A1B9F7Y8_9DELT/5-89 ................nite--------VQRDIVLDIEQAG.PD.....CAKFISR.....R.....L.....NLP...LAEVMEELGELERLGWLKRVK.GT.........FLmKKG.L.......R.RPK.......-----HMNHTYFELSREAKLLLREL............................
A0A5S4ZPE9_9FIRM/136-226 ................leve----QEDETDLAILKFIDYAG.AE.....YAWRLGI.....N.....I.....GLD...VAESRRRLEKLLEKGLLERVE.GK.........ML.ENY.H.......R.E--.......KSWTKHMNHTYYRISREGRLYVRRL............................
C5CEI2_KOSOT/7-92 ................eile-------EEDWKILKDLYSTA.PD.....CAKFLSR.....R.....L.....RLD...LGETMRRLRTLESKGFLERVE.GR.........FL.KKK.G.......L.R-K.......PK---HMNHTYYELTRPARLYLRKI............................
H2C915_9CREN/8-100 ...................l-KKILEDQRYLKILYHLKKAN.VD.....YGKSIML.....N.....T.....KIP...LSEIVNILDDLERMGLIERVM.GA.........TL.KNT.E.......A.KFK.......LSSEVHKHHTYYSLTRAGDHLLRHL............................
D3TC09_ACIB4/1-90 ...............mnlsp--------LEIYIILHLKRAN.VE.....YAKMIMK.....F.....T.....HLS...LDKIENAITSLENKGLVERDS.GS.........AI.KRT.R.......A.RFK.......KAKEVHKHHSYYHLSKEGSLLARRI............................
A0A6P1ZH37_9DELT/2-93 ..............akpnai---------QTKIVYYLQMVG.PA.....YVKKLAE.....V.....L.....GLEesqWDEVRAAIKELETASLVERVP.GT.........FV.TYQ.T.......P.EGG.......-TVTKHMNHTYYRPTKKGKRFAR--gl..........................
L0JY40_9EURY/193-277 ...................v-NVLRHLPNGRTIVQRLAHTG.PD.....SPRAIAA.....E.....W.....GTE...FEYVRHLCRVLRRVGLVAQCD.SG.........--.---.-.......-.---.......-------------------------pvdgegrsadrmyymatetgddvleav.
A0A8J8CEQ5_9EURY/193-285 ...................v-NVLRHLPDGHTLVERLARGG.PD.....YPRMSAR.....D.....L.....EME...FEYVRHLYRALRQVGLVMKYE.GS.........TI.KGT.E.......R.SLK.......PKTETHRKHTYYVTTDRGDEVRRR-v...........................
F0S2Q3_DESTD/7-97 ...............skril------DELDIKILYYIYKVG.PA.....YIKKLCQ.....R.....L.....QED...FDIIRKHIKKLEQLGYLERVS.GR.........IV.EYRiD.......R.KNK.......--VTKHRNHTYYNVTRKGRHFIRNI............................
L0AIU2_NATGS/94-186 ...................l-DPLPADPVAYLLCYHLDAVE.GN.....YPKSIAG.....H.....L.....DAE...RSQVRTLCTEMEQSGVLDRIE.SG.........TV.KQR.R.......V.KAK.......MADEVRQHHTYYRLSRDGDHLLRFL............................
A0A6A9T1Z5_9EURY/1-42 ..................mq---------------------.--.....-------.....-.....-.....---...------------------PYE.GS.........II.KGS.E.......R.KLS.......PKDETHKKHTYYVTTTVADRILRE-e...........................
A0A1Q1FPF6_9EURY/193-285 ...................k-NVLRHLPDGQTIAKRLARGG.PD.....YPRMTAD.....E.....L.....EMD...FEYIRHLYRALRRVGLVTTYQ.GS.........TI.KAS.E.......R.KLK.......PKDETHRKHTYYVTTAVADELLREL............................
A0A256KMX0_9EURY/31-96 .............sltrsde-----------RLLSYLADVG.AD.....YQAFIAG.....N.....T.....GLY...DDHVESRLTALADAGLVERVS.GE.........AV.YR-.-.......-.---.......-------------------------vtdagrea....................
A0A2T9X0L7_9CREN/102-194 ..................ae--LIRNNPDYLSFLSLAEKLN.AD.....HALTYAK.....L.....S.....KKT...LEDAIRILEELVRMGLLEEKH.DK.........II.KFG.E.......R.KAK.......PKKETRTHHKYYGLTREGELLMRYL............................
A0A1H6J9N4_9EURY/6-68 .............cadldrt---------DERVLSYLQECG.AD.....YPALIAG.....N.....T.....GLH...VAHVERRLETLADTGLVEPVS.GE.........VI.Y--.-.......-.---.......-------------------------rltd........................
A0A6G2HD06_9EURY/21-90 ..........tgivvtrsda-----------RALAYLVESG.AD.....YPALIAG.....N.....T.....GLH...VAYVERRLTTMAEAGLVEEVS.GE.........VV.YR-.-.......-.---.......-------------------------ittagrdal...................
Q96YS5_SULTO/9-101 ..................ll--EILKDKRMLEILKHLKKAN.VD.....YGKSIML.....N.....T.....KIP...IQEVVDLLDKLEKIGLIERVH.GA.........TL.KNT.E.......A.KFK.......LSKEVHKHHTYYKLTREGDHLLRQL............................
A0A2T9WVC2_9CREN/6-98 ...................a-RILIERRELLTVMRHLKRAG.ID.....YGKSISR.....N.....T.....GLP...LQNVLEILDELEKLGLIERVQ.GK.........VL.KRS.E.......A.RYK.......LSNEVRKHHVYYRLSRQGELILREL............................
G0EFH4_PYRF1/123-214 ...............vllsl------SPLHTYILLHLRMTC.TD.....YAKSIAR.....T.....V.....KMP...IEDVVLTLDRLEELGLIERVH.GS.........AL.KRT.E.......A.KLK.......LSHEVRKHHTYYKLSRSGEMLVRS-v...........................
A0A031LMH1_9CREN/111-203 ...................i-ELVKNDELSRDILRLAEELN.AD.....HALTYSK.....L.....T.....HKK...LEEVTPKLEELEKMGLLEEAG.SK.........II.KFG.E.......R.KSK.......PKKETRTHHKYYGLTRIGELVVREM............................
A0A1Q1FH04_9EURY/193-285 ...................k-NILRHLPDGQTIAKRLARGG.PD.....YPRMTAE.....E.....L.....AMD...FEYVRHLYRALRRVGLVTTYE.GS.........TI.KGS.E.......R.KLK.......PKDETHRKHTYYVTTSVAEELLREL............................
C8VZV7_DESAS/117-207 ................ldee----IEDEKDMQILTFLDYAG.AE.....YAWRLGI.....N.....I.....GID...VVEARERLERLLEKGLLEKVQ.GT.........ML.ENY.H.......-.RAK.......DW-TKHMNHTYYRISRQGKHYLRQL............................
N0BK51_9EURY/102-194 ...............lssit-----GYDAALDIIEYLAKAE.CE.....HAGWLAR.....V.....F.....SMK...VSDVQSLLTKLLDLGLLSECK.AK.........VL.KKK.H.......R.KGK.......PKKETRTHHTYYRLSRLGEMMLRYI............................
C9R7Q1_AMMDK/3-94 ..........atlndqeell---------DLKILAYLKKLG.PE.....YAKFLAR.....Q.....L.....GLS...LEESTERLRRLAARGLIKRVE.GR.........IV.KYY.H.......R.QRK.......SVK--HRNHTYYDITREGELLLRE-a...........................
Q9HLB2_THEAC/8-100 ...................i-DELINDYDMLRVLKHFTIAH.VD.....YAKNITR.....Y.....T.....EIP...QMRVREYLKRLKDLGLLDYYT.NT.........SI.KRT.E.......A.KLK.......KSAEVHKHHTYYQINKKAEAVLKEI............................
A0A6F8ZDH0_9FIRM/18-106 ...........eegtdlldr-----------KLLAYFKALG.PD.....YAKLIGF.....R.....F.....ARP...VDEVRARLEHLEALGLVERVE.GR.........IV.KYY.H.......R.RVK.......AVK--HRNHTYYQLTREGDHFLRR-h...........................
Q5JG76_THEKO/14-106 ..................yr--GLELLPVHLYVLAHLKKAG.VD.....YAKMMVK.....M.....S.....ELP...LSLIEDAIRDLMEAGLVERDS.GS.........AI.KRS.K.......A.RFK.......KAFEVHKHHTYYRLSREGELFVRRI............................
T0LX01_9ARCH/11-103 ..................ll--EVLKSPEMLRVLRHMHLAK.VD.....YAKNTSR.....Y.....T.....EIP...LMRVTDYMKRLHSMRLLDIYE.NT.........SI.KRT.S.......A.KLK.......KSAEVHKHHTYYQINRNGDILLKE-v...........................
Q6KZK1_PICTO/7-99 ...................k-RRLIENNEMLTVLEHFQVAK.VD.....YAKNIMR.....Y.....T.....EIP...KMKISHYLGILYDMGLLEKYT.NT.........SI.KRT.D.......A.KLK.......KSAEVHKHHTYYQMTNKAHYILKDL............................
V5A3Z8_9ARCH/193-285 ...................l-NALRHLPDGQQLVRRLARGG.PD.....YARMTAE.....E.....L.....DMG...FEYVRHLYRALRRVGLVTEYE.GS.........TI.KAS.E.......R.KLK.......PKDETHRKHTYYITTDRAERMVREL............................
D9PZR9_ACIS3/107-199 ...................f-EYLTGHKNVLKLLLFLFEVE.NE.....HAGTLAK.....V.....V.....GDT...PCNTVDLLDRLETLGLVTKVK.EK.........VI.KAS.H.......R.KAK.......PKPETRTHHVYYKVSELTKMLIRY-s...........................
N0BK51_9EURY/2-94 ..............ldiakl------SPLHIYILIHLRRAN.ID.....YAKSISK.....I.....T.....KID...QQEIEKALKELEELGLIDRSH.GS.........AI.KRT.A.......A.RFK.......LSHEVHKHHTYYCLTRLGEHTSRM-l...........................
A0A238WVB1_HALVU/22-89 ...........tgldltaad----------ERILAYLDRAG.PD.....YPALVAG.....N.....T.....GLH...VAYVEKRIAMLAAAGFLEPVS.GE.........VI.YR-.-.......-.---.......-------------------------itdpghd.....................
A0A2U9IF42_9CREN/111-203 ...................i-DMVKNDDLAKTILNLADELN.AD.....HALTYSK.....L.....T.....HKT...LEEVTPKLEELERMGLLEEAK.AK.........II.KFG.E.......R.KSK.......PKKETRTHHKYYGLSRTGELVVREM............................
A0A8J8CEQ5_9EURY/94-186 ..................la--PLPADPVAYLICYHLDTVE.GN.....YPRSMAG.....H.....L.....DAD...RAHVEELCEEMERAGLLERVE.SG.........TV.KQR.N.......V.KAK.......AADEVRQHHTYYRLSREGDHLLRFL............................
A0A2T9X0L7_9CREN/1-92 ...................m--EVLKDERYLKILRHLKVAN.VD.....YGKSIMK.....N.....T.....KIP...IDQVVMLLDDLEKMGLVERVP.GA.........TV.KNT.E.......A.KFK.......LSHEVHKHHTYYRLSRLADHLLRNL............................
A4YIE5_METS5/9-101 ...................l-KKLIEDKRYLMVLQHLRKAN.VD.....YGKSIML.....N.....T.....KIP...IEEVVIILDKLENLGLIERVK.GA.........TL.KNT.E.......A.KFK.......LSSEVHKHHTYYSLTRAGDHLLRYL............................
F4B6B1_ACIHW/111-203 ...................i-DLVKNDDLAKDILRLAEELN.AD.....HALTYAK.....L.....T.....HKT...LEEVTPKLEELERMGLLEEAK.AK.........II.KFG.D.......R.KSK.......PKKETRTHHKYYGLSRIGELVVREM............................
A0A4D6HH51_9EURY/94-186 ..................la--PLPADPVAYLICYHLDAVE.GN.....YPRSMAG.....H.....L.....DAE...RGQVEDLCEEMETAGVLERVE.SG.........TV.KQR.R.......V.KAK.......QAEEVRQHHTYYRLSRQGDHLLRFL............................
A0A256IAL3_9EURY/31-96 .............sltrsde-----------RLLSYLADVG.AD.....YQAFIAG.....N.....T.....GLY...DDHVESRLTALADAGLVERVS.GE.........AV.YR-.-.......-.---.......-------------------------vtdagrea....................
A0A6A9T5B5_9EURY/30-90 ..............itrsde-----------RVLAYLDDVG.TD.....YPAFVAG.....N.....T.....GLY...VDHVESRLAALAAAGLVERVT.GE.........SV.---.-.......-.---.......-------------------------ygltda......................
A0A1I6DYB4_9FIRM/13-98 ..............dileel---------DFKLLEYLYNIE.AD.....CAKFISR.....K.....L.....KIN...LGETMQRLKHLEKLGFLERVK.GT.........FL.KRK.D.......L.-YK.......PK---HMNHTYYKLVNKARLVLKH-k...........................
A0A0Q0RY96_9ARCH/7-99 ...................i-KNLVFDNQLLMVLQHFNLAK.LD.....YAKNIKI.....Y.....T.....SIP...QMNVNIYLERLENMGLIEKYS.GS.........SI.KRT.E.......A.KLK.......KTNEVHKHHTYYLLTNKGHYILKS-i...........................
A0A031LMH1_9CREN/9-101 ...................l-REVLRDGRFLKVLLHLKKAN.VD.....YGKSIML.....N.....T.....KIP...IQEVIDILEQLEKIGLIERVH.GA.........TL.KNT.E.......A.KFK.......LSSEVHKHHTYYRLTRDGDHLLRNL............................
F6DSP3_DESRL/113-212 ......yralldkgcleeev-----ENPLDLEILKFIEYAG.PE.....YAWRLSI.....N.....V.....NIT...VEKARECLEKLLWKGLLERVP.GN.........ML.GNY.H.......R.QKD.......--WTKHMNHTYYRITREGRLYLRQL............................
A0A6F8ZJK7_9FIRM/15-120 .................aff----QEHPLAYQVLKHTWTYG.PD.....TPTIIRK.....R.....LlghrsGVG...VEVIREAYALLLEAGLVERMP.GKeldrnqltsSV.KKT.L.......K.RRA.......KYHTPRKTHTYYRLSRTGELVARAL............................
T0M289_9ARCH/11-103 ...................l-KEVLSSHEMLKVLRHMHTAK.VD.....YAKNTTR.....Y.....T.....DIP...QIRVTEYLLRLRSLGLLDTYE.NT.........SI.KRT.A.......A.KLK.......KSAEVHKHHTYFQINRSGDILLKK-a...........................
A0A830GTZ9_9CREN/7-99 ..................lr--AVLLDRRLMAVMIHLKRAN.VD.....YGKSIMK.....D.....T.....KIP...LPDVISILDELERRGLVERID.KP.........VL.KNT.Y.......A.KFK.......RKHEVRKHHVYYTLSRDGELILRR-v...........................
F2KN96_ARCVS/106-198 .................lah---LTGCNVTFPILQFFRMAG.CE.....HAGVVAR.....A.....F.....SMR...IDECRELLAKLVQLGLLVYCD.SK.........VL.KRK.H.......R.KAK.......AKKETRTHHRYYRLSRLAEMLLRY-a...........................
R1E4M7_NANST/9-101 ...................a-KMLKDDPDYFKVLNHLKIAN.LD.....YAKNISK.....Y.....T.....KID...INKVNKILEELKEIGLVEEVH.SR.........TV.KRS.K.......A.RLK.......KQFEVRMHHTYYKLTLLGKQVYKY-l...........................
A0A496AP79_9BACT/70-162 ..............keieql------DQTDYLILKHHQEMG.MD.....YSKVVAE.....T.....L.....HIP...LDEIQDRHKKLRELGGLKRVE.GR.........II.HYR.K.......N.IVK.......GKWIKHRNHTYYEITPEGNEWIH--tl..........................
W7KLG6_9CREN/10-102 ..................ll--EVLKDKRYLEVLRHLKKAN.VD.....YGKSIML.....N.....T.....KIP...IDQVVEILDNLEKLGLIERVH.GA.........TL.KNT.E.......A.KFK.......LSSEVHKHHTYFKLTREGDHLLRNL............................
G4RNA2_THETK/15-90 ...............leddl---------------------.--.....YGKSIAV.....N.....T.....GIP...LQRVLEILEKLEALGLVERARgGK.........TL.KRT.E.......A.RYK.......LGHEVRKHHVYYRLTRKGRRLLRQ-e...........................
Q97WF9_SACS2/113-205 ...................m-DIVKNDNLALNILRLADELN.AD.....HALTYAK.....L.....T.....HKR...LEEITPKIEELVKMGLLEEKN.SK.........II.KFA.D.......R.KAK.......PKKETRTHHKYYGLSRIGELVVREM............................
A0A1X4XWH3_9DELT/1-90 ................mckl------DDLEIKILKYHKQKG.CD.....YSKSLAK.....E.....L.....NIK...LCEAFMVHKKLLSLGYLEKVS.SR.........LT.KY-.K.......V.NNK.......TKIIKHRNHTYYQLSQNGKQFLKDL............................
M0C5A2_9EURY/193-278 ...................v-NVLRHLPDGKAIVQRLSRIG.PD.....SPRTTAA.....E.....W.....EME...FEYVRHHYRSLRRVGLVTQCD.GK.........PV.DGE.-.......A.RSA.......------MDRTYYATTETGDDLL---esv.........................
G4RM81_THETK/1-93 ...................m-KDVLRKKLYIDILFHLKRAY.ID.....YGKSIAK.....N.....L.....RVD...LSEVIDALERLEELGLIERVG.GH.........TL.KRS.K.......A.RFK.......LSNEVRKHHIYYKLSRAGELLLRE-v...........................
Q96YS5_SULTO/111-203 ...................i-DLVKNDQMAIDILKIADEVN.AD.....HALTYAK.....L.....L.....HKP...LEEVTPKLEELERTGLLEEKN.AK.........II.KFI.D.......R.RSK.......PKKETRTHHKYYGLSRIGELVVREM............................
Q18IX1_HALWD/193-285 ...................q-NVLRHLPDGHTLIQRLARGG.PD.....YPRMTAD.....E.....L.....DME...FEYVRHLYRALRQVGLVTEYE.GS.........TI.KAT.E.......R.KLK.......PKDETHRKHTYYIVTDRGDEAFRRL............................
F2KN95_ARCVS/5-108 .............enlddls----------RRVLLHLLIFG.PD.....TPKLMGKrllgeR.....T.....NID...PPNIKEVCIKLCEMGLVKRRD.GK.........TLpKRT.PtssikpwI.KIK......aKSKETAKHGQYFELTKEGKKVAK--av..........................
A0A1S6J0M0_9FIRM/1-91 ................mdie----IEDDKDIEILQFIDYAG.PE.....YAWRLGI.....N.....V.....GLD...VEESRKRLEKLLAKGLLERVP.GN.........ML.EGY.H.......R.QKD.......--WVKHMNHTYYRITREGRHYLRKL............................
A4YIE5_METS5/111-203 ...................i-EYLQGDELALNIVRLAEELN.AD.....HALTYAK.....L.....T.....KKD...LEEVNSKLEQLVKMGLLEEVN.AK.........II.KFG.D.......R.KSK.......PKKETRTHHKYYGLTRIGELTVREM............................
L0ABP7_CALLD/119-211 ...................f-KKITNYDNTLKLLIFLRKAE.NE.....HAGTIVK.....V.....F.....GLD...MDKTINILEKLENLGLVIPVK.EK.........II.KAK.H.......R.KAK.......PKEETRTHHIYYRITRLTEMILRY-s...........................
A0A2C6MER9_9FIRM/4-94 ................lsee----IEDETDLAILKFIDYAG.PE.....YAWRLGI.....N.....I.....GLD...VEESRRRLEALLEKGLLEKVP.GN.........ML.EGY.H.......R.QKD.......--WTKHMNHTYYRITREGRHYLRKL............................
A0A1Q1FPF6_9EURY/94-186 ..................la--PLPADPVAYRILYHLDTVE.GN.....YPRSMAG.....H.....L.....DAE...RKQVEALCEEMETAGLLERVE.SG.........TV.KQR.R.......V.KAK.......QADEVRQHHTYYRLSREGDHLLRFL............................
A0A510E6J0_9CREN/12-104 .................lkd---VLIDSRYLQVLEHLKKAN.VD.....YGKSIML.....N.....T.....KIP...IQEVVDILDYLEKKGLIERVH.GA.........TL.KNT.E.......A.KYK.......LSSEVHKHHTYYTLTRIGDHLLRRL............................
F8A7Z5_THEID/7-92 .................nil------DEKDWKILKDLYAHA.PD.....CAKFLSR.....R.....L.....RFE...LGDTMERLRKLENLGFLERIE.GR.........FL.KKK.G.......L.KR-.......---PKHMNHTYYELTRSCRLYLRK-d...........................
A0A494X1S9_9FIRM/4-93 ............kneqeell---------DLKILAYLKKLG.PE.....YAKLLAI.....R.....L.....GLS...LEESIERLRRLAARGLIKRVE.GR.........IV.KYY.H.......R.RRK.......SVK--HRNHTYYDLTREGELLLRE-a...........................
L0AIU2_NATGS/193-278 ...................v-NVLRQLPDGHAIVQRLARIG.SD.....SPRATAA.....E.....W.....EMK...FEDVRHLYRALRRVGLVTQYD.GE.........--.---.-.......-.---.......-------------------------pgndqaqsatdrtyytttaagndvleav
A0A4U7F8Q0_9EURY/27-95 ............sglaltrs---------DERVLAYLDDVG.TD.....YPAFVAS.....N.....T.....GLY...VEHVESRLDALDAAGLVERAT.GE.........AV.---.-.......-.---.......-------------------------frvtdagrda..................
Q4J7U2_SULAC/107-199 ...................a-EIVKDDEVGLKLLYYAEELH.SD.....HALTYSK.....L.....L.....RKP...LEEITPKIEELERMGLMEEKN.SK.........VI.KFR.E.......R.RAK.......PKKETRTHHKYYGLTRLGELLVREL............................
M0C5A2_9EURY/94-186 ...................l-DPLPADPVAYLICYHLNTVE.GN.....YPKSIAG.....H.....L.....DAE...RSQVRTLCKEMEQSGLLERVE.SG.........TV.KQR.R.......V.KAK.......MADEVRQHHTYYRLSRDEDHLLRFL............................
A0A1I6EF79_9FIRM/5-70 ...............wdvle-------EKDLTILQYLYNIE.AD.....CAKFISR.....K.....L.....RIS...LEETMQRLKHLEKLGFLERVR.GT.........--.---.-.......-.---.......-------------------------fpngtiidek..................
A0A4P2VBS6_9ARCH/120-212 ..................aq--ALDGDDLAFALLRVARRIG.VD.....HALTYAR.....L.....V.....GRP...LEQVEAELERLVGMGLMEIPR.SR.........VV.KRG.D.......R.KAK.......PKPETRVHHRYYRLSREGDLLLRDI............................
Q18IX1_HALWD/94-186 ..................la--PLPVTPVAYLICYHLNAVE.GN.....YPRSMAG.....H.....L.....DAR...REQVDELCKKMETAGLLERVE.SG.........TV.KQR.R.......V.KAK.......QADEVRQHHTYYRLSREGDHLLRFL............................
M1QI07_9AQUI/9-99 ..............eyelsd--------LELKILKYHKIMG.PD.....YSKLISH.....R.....F.....HIS...LQEAFDIHKKLLSMGLLQKVT.AP.........II.NYH.S.......K.DKR.......LKSLKHRNHTYYDLSRTGKLLLRE-y...........................
A0A179D684_9BACT/7-91 ................ilee--------KDWLILRDLYALA.PD.....CAKFLSR.....R.....L.....RLD...LEETMQRLRRLENLGFLERVK.GR.........FL.KKK.G.......L.RRP.......----KHMNHTYYELTREARLYLRQ-t...........................
A0A7D5GI44_9EURY/5-72 .............ssltdtd----------RRVLSYLQDSG.AD.....YPALVAG.....N.....T.....GVH...IPLVERRISVLVEYGLLERVT.GE.........SV.YRI.-.......-.---.......-------------------------tadgesal....................
E1QSW4_VULDI/1-92 ..............mdgltd--------KDIAVLMHLKRAN.VD.....YGKSIAI.....N.....T.....GIP...LEEVLQILDKLESMGLIERVRgGK.........TL.KRS.V.......A.KFK.......LSNEVRKHHVYYRLSRRGELLVRSL............................
Q97WF9_SACS2/11-103 ...................l-RIILRDIRYLTVLKHLKIAN.VD.....YGKSIML.....N.....T.....KIP...LTEIVEILDDLEKLGLIERVH.GA.........TL.KNT.E.......A.KFK.......LSSEVHKHHTYYRLTREGDHLLRHL............................
A0A1W1WJH3_SULTA/15-103 ................drkl------DETDIKLLKYFKTLG.PD.....YAKLLAA.....R.....F.....NMD...VAAMRERLNYLESLNFIERVE.GR.........IV.KYY.H.......R.RMK.......SVK--HRNHTYYMISREGDHFLRQ-q...........................
A0A6I7LSY0_9BACT/69-159 ...............yssld-------EIDFDILAHHYRMG.ID.....YSLAVAA.....L.....L.....NLD...DKTVFERHRKLRQMSLLERVE.PV.........MV.QYR.K.......N.IVK.......NKWIKHRNHTYYDLTDKGRDYLK--yh..........................
D9PZR9_ACIS3/4-96 ..............klmsls-------PLSLYILFHLKKAN.VD.....YAGSISK.....V.....I.....EVP...IDKVVDELDRLEAAGLIQRRVgGS.........SI.KRS.E.......A.RFK.......LSDEVHKHHVYYELSREGEGLVRSL............................
V5A3Z8_9ARCH/94-186 ..................lt--PLPADPVAYLLCYHLDTVE.GN.....YPRSMAG.....H.....L.....DAE...RGHVEELCETMLDAALLERVE.SG.........TV.KQR.N.......V.KAK.......QADEVRQHHTYYRLSRDGDHLLRFL............................
S0ARL8_FERAC/7-99 ...................k-KKLAMDHQMLMVLEHFQLAK.LD.....YAKNVKI.....Y.....T.....SIP...QENVEIYIERLYSMELLEKYS.GS.........SV.KRT.Q.......A.KLK.......KTNEVHKHHTYYELTNKGHYILKDM............................
L0JY40_9EURY/94-186 ...................l-DPLPTDPVAYLICYHLDAVE.GN.....YPKSIAG.....H.....L.....DAE...RNQIRTLCKEMEESGLLERVE.SG.........TV.KQR.R.......V.KAK.......LADEVRQHHTYYRLSRKGDHLLRFL............................
W7KLG6_9CREN/112-204 ...................i-ELVKGDDLAKNILKLADELN.AD.....HALTYAK.....L.....T.....HRT...LEEIMPKLEELERIGLIEEAK.AK.........II.KFG.D.......R.KSK.......PKKETRTHHKYYGLSRIGELVIREM............................
A0A498GCI9_9EURY/193-285 ...................l-NVLRHLQDGQRIATRLARGG.PD.....YPRMTAE.....E.....L.....EMD...FEYVRHLYRALQRVGLVTTYE.GS.........TI.KGS.E.......R.KLK.......PKSETHRKHTYYVTTPVAEQLLRDL............................
A0A1Q1FH04_9EURY/94-186 ..................la--PLPADPVAYRILYHLDTVE.GN.....YPRSMAG.....H.....L.....DAE...RKQVEALCEKMETAGLLERVE.SG.........TV.KQR.R.......V.KAK.......QADEVRQHHTYYRLSREGDHLLRFL............................
F4B6B1_ACIHW/9-101 ...................l-KEVLKDKRYLQVLQHLKKAN.VD.....YGKSIML.....N.....T.....KIP...IQEVVDILDKLEALGLIERVH.GA.........TL.KNT.E.......A.KFK.......LSSEVHKHHTYYRLTREGDHLLRNL............................
A0A1Z5HT67_9THEO/12-98 ...............wdile-------ENDLKILKYLYNIE.AD.....CAKFISR.....R.....L.....RIS...LEETMQRLKHLEKLGFLERVK.GT.........FL.KRK.D.......L.-YK.......PK---HMNHTYYKLTRKARLDIR--sw..........................
A0A1W1WLJ3_SULTA/13-119 ...........knffnqhpi---------AYQLMVHTKLYG.PDtpmivHKRLLGQ.....R.....S.....GLS...IEEIRDNYRLLLEFGLMEKTS.GKeldrnhltsSI.KKT.L.......K.RRQ.......KYHTPRKTHTYYQLSRKGELVIRNL............................
A0A6G7PYB1_9BACT/5-93 ...........eklkglndq---------ERAIIFDLRQNG.PD.....CAKFISR.....R.....L.....GLE...LGLTMEILRDLERKAILERVS.GT.........FL.KKK.G.......L.RRP.......----KHMNHTYYRLTRPMRIFFRR-t...........................
F2KN96_ARCVS/6-98 ..................fk--SVELKPLQVYILFHLRRAN.ID.....YAKSIAR.....T.....L.....KME...QQEIEKVLKELEDMRFIERTH.GS.........AI.KRS.E.......A.RFK.......LSHEVRKHHTYYGLTKDGEHTIRSI............................
A0A4Q2WH88_9FIRM/118-208 ................ldee----KEDDTDLEILKFIDYAG.PE.....YAWRLGI.....N.....I.....GIK...VEEARRRLSLLLEKGYLERVE.GN.........ML.DNY.H.......R.-AK.......DW-TKHMNHTYYRITREGRLYLRRL............................
V4Y033_9ARCH/22-89 ............emsltrsd----------ERVLAYLADAG.AD.....YPALVAG.....N.....T.....GLY...ASHVETRLDVLAQAGLVEAAT.EE.........IV.Y--.-.......-.---.......-------------------------ritddgrda...................
D2REQ1_ARCPA/2-90 ...............qffpi---------HLYILLHLKRAN.VN.....YVKMIAK.....M.....I.....ELS...LELVKTALDDLMKAGLVERDQ.GS.........AL.KRS.K.......A.KFK.......KAFEVRKHHTYYKLSREGDLLVRRI............................
A0A8J8PAB9_9EURY/193-285 ...................l-NVLRHLPDGRRLVRRLDRGG.PD.....YARMTAE.....E.....L.....GME...FEYVRHLYRALRRVGLVTEYE.GS.........TI.KAS.E.......R.KLK.......PKDETHRKHTYFITTDRAETLLREL............................
L0ABP7_CALLD/10-108 ......iiketlqriyeisp--------LDLYILFHLKKAN.VD.....YGRSIAS.....I.....L.....GIS...IDIITDELDKLEKMGLIERHQ.GS.........AI.KRS.E.......A.KFK.......LAEEVRKHHTYYKLTRETCLSIRKL............................
Q4J7U2_SULAC/5-97 ...................l-KEVLKDKRLLEVLRHLKRAN.VD.....YGKSIML.....N.....T.....KIP...LTEVLDVLDKLESLGLIERVT.GA.........TL.KNT.E.......A.KFK.......LSQEVHKHHTYYRLTRDGDHLLRRL............................
A0A348B1X3_9CREN/1-90 .................mlg------NELLIKVMRHLRKAN.ID.....YGKSVAL.....N.....V.....GVP...LEEAVAALEELERRGLIERVH.GS.........AV.KNT.E.......A.KFK.......LSSEVRKHHTYYRLTRCGEHLLREL............................
G0EFH4_PYRF1/5-106 ................ldgl---------SLKVLLHLYEYG.PD.....TPKLMCR.....RllgerT.....QLD...PALLERVLEAIAEKGLVKRMQ.SK.........TVpKNT.A.......TsSIKpwikvrvKSSEVRRHGQYYELAREGEKLAKR-v...........................
A0A2S3QGS6_9FIRM/3-90 .................pnl------DETDLKLLKYLKTLG.PD.....YAKLLAS.....R.....F.....HID...LESMRSRLAYLESINFIERVE.GR.........IV.KYY.H.......R.RMK.......SVK--HRNHTYFMIAREGDHYLRA-q...........................
M0FCV4_9EURY/18-79 .............sltrsde-----------RLLAYLADVG.AD.....YQAFIAG.....N.....T.....GLY...DDHVESRLTALADAGLVERVS.GE.........AV.Y--.-.......-.---.......-------------------------rvtda.......................
A0A510E6J0_9CREN/114-206 ..................is--LLKSDELYLSLVSLADQLN.AD.....HALTYAK.....L.....T.....HKP...IEEIIPKLEELERMGIMEEAK.AK.........VI.KFG.E.......R.KSK.......PKKETRTHHKYYGLTRTGEMVVREM............................
A0A8J8PAB9_9EURY/94-186 ..................la--PLPADPVAYLLCYHLDRVE.GN.....YPRSIAG.....H.....L.....DAD...RSHVEALCEELIEAGLLERVE.SG.........TV.KQR.R.......V.KAK.......QADEVRQHHTYYRLSREGDHLLRFL............................
G0EFH4_PYRF1/224-316 .................lal---ITGHSKAHQLLQFLSEAE.HE.....HIVAIAQ.....A.....L.....SLQ...LEEAQRLIDKLIELGLVAETK.PK.........VL.KMK.H.......R.RAK.......PKKETRCLHRYYRLTRLAELLIRY-s...........................
A0A650CRA2_9CREN/112-204 ...................i-DLVKNDQFALDILKIADEVN.AD.....HALTYSK.....L.....L.....HKP...LEEITHKLEELERMGLLEEAQ.AK.........II.KFR.E.......R.RSK.......PKKETRTHHKYYGLSRIGELVVREL............................
A0A4P2VBS6_9ARCH/19-110 ..............prvlsi-------PGALGVLRHLRRAH.VD.....YGRSVAA.....S.....L.....HTS...IEVAVSTLESLESMGLVERVP.GS.........SV.KRS.D.......A.KMK.......LADEVHKHHTYYRLSREGDTLLRSL............................
A0A650CRA2_9CREN/10-102 ..................lm--EVLKDKRLLEVMKHLRKAN.VD.....YGKSIML.....N.....T.....KIP...IQEVVELLDRLERLGLIERVH.GA.........TL.KNT.E.......A.KFK.......LSKEVHKHHTYYTLTREGDHLLRQL............................
A0A2U9IF42_9CREN/9-101 ..................ly--EVLKDKRYLEVLEHLKKAN.ID.....YGKSIML.....N.....T.....KIP...IDQVVDILDKLEQLGLIERVH.GA.........TL.KNT.E.......A.KFK.......LSSEVHKHHTYYTLTRDGDHLLRNL............................
A0A418M0L7_9BACL/3-88 ................fdgv---------DVKILAYFKALG.PD.....YAKLVAF.....R.....F.....GLS...LENSRARLERLELAGFIEKVE.GR.........IV.KYY.H.......R.RVK.......AVK--HRNHTYFQITKDGEQFLRD-e...........................
A0A348B1X3_9CREN/98-189 .............yleslge--------TDLKVLEVAEKVN.VD.....HALTFAK.....L.....T.....GMS...LEEVNRELERLVKLGLMEEDK.SK.........VI.KFG.E.......R.KAK.......PKRETRTHHKYYRLSRLGELVVRR-s...........................
A0A1Q6DSU4_9EURY/136-229 ................vdap-----SDPVSILVLAHLKKAK.GD.....YPKNIAL.....T.....Ln...qDIG...VKRCRRCCQALKENGLLEKIP.SG.........ML.KRK.N.......V.KLK.......RSLETHQHHTYYTLSDTGSHLLRKL............................
A8M9U9_CALMQ/1-92 ................mnel----TD--KDIAVLVHLKKAN.VD.....YGKSIAL.....N.....T.....GIP...LQEVLQILDKLEYMGLVERVKgGK.........TL.KRS.V.......A.RFK.......LSSEVRRHHVYYRLSRSGELLIRA-s...........................
A0A498GCI9_9EURY/94-186 ..................la--PLPADPIAYLVCYHLDTVE.GN.....YPRSIAG.....H.....L.....DAE...RNHVEDLCSEMETAGLLERVE.SG.........TV.KQR.R.......V.KAK.......QADEVRQHHTYYRLSREGDHLLRFL............................
#=GC seq_cons ...................h.........thplLtaLcpss.sD.....Yu+tlut.....p.....h.....pls...lpclpphLccLcphGLlE+sc.Gp.........sl.Ktp.c.......t.+hK........tpEs+p+HTYYpLoRpG-hllRp.............................
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