#=GF ID   DUF228
#=GF AC   PF02989.18
#=GF DE   Lyme disease proteins of unknown function
#=GF AU   Griffiths-Jones SR;0000-0001-6043-807X
#=GF SE   Pfam-B_1298 (release 6.4)
#=GF GA   25.00 25.00;
#=GF TC   133.60 132.90;
#=GF NC   24.70 19.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR004239;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF SQ   21
#=GS G5IXI8_BORBU/38-187  AC G5IXI8.1
#=GS Q9S0G6_BORBU/1-186   AC Q9S0G6.1
#=GS Q9S055_BORBU/1-187   AC Q9S055.1
#=GS W6THM3_9SPIR/19-196  AC W6THM3.1
#=GS Q9S0D4_BORBU/1-186   AC Q9S0D4.1
#=GS Q9S0G5_BORBU/38-247  AC Q9S0G5.1
#=GS O50933_BORBU/16-200  AC O50933.1
#=GS W6TWA0_9SPIR/52-256  AC W6TWA0.1
#=GS Q9RZX8_BORBU/1-187   AC Q9RZX8.1
#=GS Q9R3E0_BORBU/38-247  AC Q9R3E0.1
#=GS Q9S006_BORBU/1-190   AC Q9S006.2
#=GS Q9S054_BORBU/38-247  AC Q9S054.1
#=GS W6TFA0_9SPIR/1-184   AC W6TFA0.1
#=GS Q9S0G4_BORBU/1-190   AC Q9S0G4.2
#=GS Q9S0D3_BORBU/38-247  AC Q9S0D3.1
#=GS Q9R2P9_BORBU/1-185   AC Q9R2P9.1
#=GS W6TG61_9SPIR/1-185   AC W6TG61.1
#=GS Q9R2Q0_BORBU/1-185   AC Q9R2Q0.1
#=GS Q9S0I9_BORBU/38-247  AC Q9S0I9.1
#=GS Q9S0A0_BORBU/38-247  AC Q9S0A0.1
#=GS Q9S0D2_BORBU/1-190   AC Q9S0D2.2
G5IXI8_BORBU/38-187             ...............................................QAEEVQAKDPYLDSVKELDDVLLKFKKYSKSMS-SI..........----ENRVFSSSGGcfklknervnaysfTCSSFADKIEEYlydPANSFPYKRGVKLVPKEN.......SIYVEVGADTDMYGICVDVCEFSSTAYVLPITN.NFEGYLVTR...NPSIKMGEILD-------------...----------------..------..............--------------ksaff
Q9S0G6_BORBU/1-186              ...........................................msdg---ITKIKEDFDKKVAEIKALMKNPQQDAGLLSNSV..........DFRDKNLIYSNSDG..............VFTSSKDKIENY...PAKGYPYKRGVKLSFSADs....ttELEVEAGGGDDLYGICTDIDEFTGMATVVPITN.NFTGYLTFKk.nGNGVNPGDKLHFNAQGELEKNGGN...DKSVNAIALSKVHKLT..--EELS..............IVLASVFGNRALK-g....
Q9S055_BORBU/1-187              ...........................................msdg---ITKIKEEFDKKVAEIKALMKNPQQDAGLLRNSV..........DFRDKNLIYSNSDG..............VFTSSKDKIENY...PAKGYPYKRGVKLSFSADg....ttELEVEAGGGDDLYGICTDIDEFTGMATVVPIIN.NFTGYLTFKkngQNGVNPGDKLHFNAQGELEKNGGN...DKSVNAIALSKVHKLT..--EELS..............IVLASVFGNRALK-g....
W6THM3_9SPIR/19-196             ..................................drleselaslklg-------------KQSEVLMRLKDHTTYPAVFDREV..........QFGSLDIYFAHRGG..............LQYSLADKFENY...QDIGFCYKRGVKLVVQNG......mSTCVTRGGGSDLYGICIDYDDLTRTATVISIAN.SFECILL-S...DMNVKSGDKLVFDDMGVLSKVKAN...GTYMQALALSDALEFK..DKSGFY..............GAKVML--------iskp.
Q9S0D4_BORBU/1-186              ...........................................msdg---ITKIKEEFDKKVAEIKALMKNPQQDTGLLSNSV..........DFRDKNLIYSNSDG..............VFTSSKDKIENY...PAKGYPYKRGVKLSFSADg....ttELEVEAGGGDDLYGICTDIDEFTGMATVVPITN.NFTGYLTFKk.nGNGVNPGDKLHFNAQGELEKNGGN...DKSVNAIALSKVHKLT..--EELS..............IVLASVFGNRALK-g....
Q9S0G5_BORBU/38-247             ...............................................QAEEVQAKDPYLDSVKELDDVLLKFKKYSKSMS-SI..........----ENKVFSSSGGcfksknervnaysfTCSSFADKIEEYsydPANSFPYKRGVKLVLKES.......SIYVEVGADTDMYGICVDVCEFSSTAYVLPITN.NFEGYLVTR...NPSIKMGEILDINNNGVIIKAGGG..pPTVINAYALSDSFTIN.fAPEDEHqdqarypkqeysinLIKVAIFGNRGLEK.....
O50933_BORBU/16-200             ..............................................a-SKVELESQLESLKKNQAQKIVLDKLQSVNASSYPVfe......shKFQDEGLYFAQKGG..............LKSSSADKFENY...QALDFCYKCGVKLIVNGS.......NLQIAKGGGSDLYGVCVDFDDFSRTGTVVPITC.SFECVLITK...DKTIKAEDKLIINSEGVLEKSSKN...ASVIHALALGPALEFK..DRRDVY..............GVRV-LFLVKQIKD.....
W6TWA0_9SPIR/52-256             sqnldsrfgtekekqyrlaylklkkytktttedlavrscakngfqgs------------------------------------..........-------------Adfpy......iltqTISSSVDKYENY...PYKGFPYKRAVKLSFDTD......gSAFVETSDDSNVYGMCVDVDEYTETAQVVPITN.NVSGYFICA...DSSIQCGDHLDFNSEGELVKASSN..lPTSINIIALSNTYKHDfrTPAEQRdssfss.ssdfiiyFAKVTIFGNKAIQ-r....
Q9RZX8_BORBU/1-187              ...........................................msdg---ITKIKEEFDKKVAEIKALMKNPQQDAGLLSNSI..........DFRDKNLIYSNSDG..............VFTSSKDKIENY...PAKGYPYKRGVKLSFSADg....ttELEVEAGGGDDLYGICTDIDEFTGMATVVPITN.NFTGYLTFKkngQNGVNPGDKLHFNAQGELEKNGGN...DKSVNAIALSKVHKLT..--EELS..............IVLASVFGNRALK-g....
Q9R3E0_BORBU/38-247             ..............................................q-AEDVQGEDPYLESISELDDVLLKFKKYSKSMS-SI..........----ENKVFSSSSGcfksknervdaysfACSSYTDKIEEYlydPANSFPYKRGVKLVPKEN.......SIYVEVGADTDMYGICVDVCEFSCTAYVLPITN.NFEGYLVTR...NPSIKIGEILDINNNGVIIKAGGG..pPTAINIYALSDSFTIN.fAPEDGNqdqnryprqeysinLIKVAIFGNRGLEK.....
Q9S006_BORBU/1-190              ...............................................MADTTQLLKDYQDKRSKLEKFMKNPQYDAGLLSNSV..........EFRDKNIQFFASGG..............TRTSKFDKLENH...PFSGYPYKRGIKRVIQEEkadqihyEPHVEAGGEDDLYGICIDIDEFSKTATIVPITN.NFEGYLVAK...DSTLKVKDKLVFNKDGALEKVTGAppnKATINAIALSDAKQIS..--NDVY..............LIKVAVFGNKAVSK.....
Q9S054_BORBU/38-247             ...............................................QAEEAQAKDPYLDSVKELDDVLLKFKKYSKSMS-SI..........----ENKVFSSSGGcfksknervnaysfTYSSFADKIEEYlydPANSFPYKRGVKLVPKEN.......SIYVEVGADTDMYGICVDVCEFSSTAYVLPITN.NFEGYLVTR...NPSIKMGEILDINNNGVIIKAGGG..pPTAINAYALSDSFTIN.fAPEDEHqdqarypkqeysinLIKVAIFGNRGLEK.....
W6TFA0_9SPIR/1-184              ...............................................MADIAKLKKEYEDKLNEIKSYMKNPSVDPGLFSNNT..........EFRGKNLHFAASGG..............TTTSSADIIENM...PSKGYPYKRGVKLDFSDAk.....hEPVVVPGGGGDLYGICVDIDDYTEIAQVVPINN.NFQGWLIAKkdnATSIAIGDTLKFNNFGELEKDTSS...SRLINAVALSKAVKLN..--ENLY..............IIHVSIFGNRA---ks...
Q9S0G4_BORBU/1-190              ...............................................MADTTQLLKDYQEKRSKLEKFMKNPQHDAGLLSNSV..........EFRDKNIQFFASGG..............TRTSKFDKLENH...PFSGYPYKRGVKRVIQEEkadqihyEPHVEAGGKDDLYGICIDIDEFSKTATIVPITN.NFEGYLVAK...DSTLKVKDKLVFNKDGALEKVTGAppnKATINAIALSDAKQIS..--NDVF..............LIKVAVFGNKAVSK.....
Q9S0D3_BORBU/38-247             ...............................................QAEEVQAKDPYLDSVKELDDVLLKFKKYSKSMS-SI..........----ENKVFSSSGGcfksknarvnaysfTCSSFADKIEEYlydPANSFPYKRGVKLVPKEN.......SIYVEVGADTDMYGICVDVCEFSSTAYVLPITN.NFEGYLVTR...NPSIKMGEILDINNNGVIIKAGGG..pPTVINAYALSDSFTIN.fAPEDEYqdqarypkqeysinLIKVAIFGNRGLEK.....
Q9R2P9_BORBU/1-185              ...............................................MSDITKIKQEFDKKVAEIQALMKNPQQDSGLLSNSI..........DFRDQNLIFSNSGG..............VCTSSKDKIENY...PAKGYPYKRGVKLSFGDGt.....tELEVEAGGGDDLYGVCSDIDEFSGMATVIPITN.NFTGYLTLKkegQNGVNPGDKLNFNQHGELEKVTGA...QKSVNAIALSKAHKLT..--EDLF..............IVLASVFGNRAIK-g....
W6TG61_9SPIR/1-185              ..............................................m-PDMKQLIKDYEDKRKALAAVIKGGSKEVELKSNTF..........DFRNKGPSVGDGGF..............TYSSSNTKIENW...PSKNYPYKCGVKITTNQIkanevhyESYVQPGGGSDLYGICIDIDDYTETAQVVPITSgGYQAWLFAK...DATIKRGDKIKFNDKGEAEKSSGS...NTIYNAIALEDTVSLP..--GNTY..............LVHVKFVGN-----sv...
Q9R2Q0_BORBU/1-185              ...............................................MSDITKIKQEFDKKVAEIQALMKNPQQDSGLLSNSI..........DFRDQNLIFSNSGG..............VCTSSKDKIENY...PAKGYPYKRGVKLSFGDGt.....tELEVEAGGGDDLYGVCSDIDEFSGMATVIPITN.NFTGYLTLKkdgQNGVNPGDKLNFNQHGELEKVTGA...QKSVNAIALSKAHKLT..--EDLF..............IVLASVFGNRAIK-g....
Q9S0I9_BORBU/38-247             ..............................................q-AEDAQGEDPYLEAINELDDVLLKFKKYVKSMS-SIenkvfgglssCFKSKN-------Ervd.......aysfACSSYTDKIEEYlydPANSFPYKRGVKLVPKEN.......SIYVEVGADTDMYGICVDVCEFSCTAYVLPITN.NFEGYLVTR...NPSIKIGEILDINNNGVIIKAGGG..pPTVINIYALSDSFTIN.fAPEDGNqdqnryprqeysinLIKVAIFGNRGLEK.....
Q9S0A0_BORBU/38-247             ..............................................q-AEDAQGEDPYLEAINELDDILLKFKKYVKSMS-SIenkvfgglssCFKSKN-------Ervd.......aysfACSSYTDKIEEYlydPANSFPYKRGVKLVPKEN.......SIYVEVGADTDMYGICVDVCEFSCTAYVLPITN.NFEGYLVTR...NPSIKIGEILDINNNGVIIKAGGG..pPTAINIYALSDSFTIN.fAPEDGNqdqnryprqeysinLIKVAIFGNRGLEK.....
Q9S0D2_BORBU/1-190              ...............................................MADTTQLVKDYQEKRSKLEKFMKNPQHDAGLLSNSV..........EFRDKNIQFFASGG..............TRTSKFDKLENH...PFSGYPYKRGVKRVIQEEkadqihyEPHVEAGGEDDLYGICIDIDEFSKTATIVPITN.NFEGYLVAK...DSTLKVKDKLVFNKDGALEKVTGAppnKATINAIALSDAKQIS..--NDVY..............LIKVAVFGNKAVSK.....
#=GC seq_cons                   ................................................u-.sphcc.a.cKlsElcslhhs.pp.uthhS.Sl..........pF+scNhhFusSGG..............spoSptDKIENY...PApuaPYKRGVKLshp-s......hplhVEsGGssDLYGIClDlDEFSsTApVlPITN.NFpGYLls+...ssolKhGD+LcFNspG.LpKsuGu...ssslNAlALScuapls....E-hh..............ll+VulFGNRulc......
//