#=GF ID   DUF2286
#=GF AC   PF10051.13
#=GF DE   Uncharacterized protein conserved in archaea (DUF2286)
#=GF AU   COGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   COGs (COG5399)
#=GF GA   24.00 24.00;
#=GF TC   24.10 24.60;
#=GF NC   23.80 20.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR017006;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Members of this family of hypothetical archaeal proteins have no
#=GF CC   known function.
#=GF SQ   32
#=GS L0ACS7_CALLD/2-141       AC L0ACS7.1
#=GS A8ME43_CALMQ/5-142       AC A8ME43.1
#=GS A0A0U3FP58_9CREN/2-138   AC A0A0U3FP58.1
#=GS A8ABB8_IGNH4/21-154      AC A8ABB8.1
#=GS G0ECK4_PYRF1/9-148       AC G0ECK4.1
#=GS A0A550D510_9CREN/2-138   AC A0A550D510.1
#=GS A0A510E2K8_9CREN/2-138   AC A0A510E2K8.1
#=GS A0A2T9X2K1_9CREN/2-141   AC A0A2T9X2K1.1
#=GS E1QV18_VULDI/6-142       AC E1QV18.1
#=GS A0A650CNY0_9CREN/2-142   AC A0A650CNY0.1
#=GS G4RML3_THETK/1-134       AC G4RML3.1
#=GS A0A2T9X0X9_9CREN/2-140   AC A0A2T9X0X9.1
#=GS A0A4S8RYV0_9FLAO/70-123  AC A0A4S8RYV0.1
#=GS Q8ZVQ1_PYRAE/1-137       AC Q8ZVQ1.1
#=GS D9PZS8_ACIS3/2-143       AC D9PZS8.1
#=GS A0A2U9IFK8_9CREN/2-139   AC A0A2U9IFK8.1
#=GS Q9YAX8_AERPE/2-140       AC Q9YAX8.2
#=GS E0SP57_IGNAA/2-138       AC E0SP57.1
#=GS A0A830GZT4_9CREN/10-148  AC A0A830GZT4.1
#=GS A0A0V8RWB4_PYROC/2-140   AC A0A0V8RWB4.1
#=GS Q4J8M9_SULAC/2-138       AC Q4J8M9.1
#=GS Q971C6_SULTO/2-138       AC Q971C6.1
#=GS Q7LXU9_SACS2/2-138       AC Q7LXU9.1
#=GS I0A1Y9_FERFK/7-146       AC I0A1Y9.1
#=GS W7KPG5_9CREN/2-138       AC W7KPG5.1
#=GS A2BM94_HYPBU/3-142       AC A2BM94.1
#=GS A0A2T9WWQ5_9CREN/6-142   AC A0A2T9WWQ5.1
#=GS H2C9G7_9CREN/2-139       AC H2C9G7.1
#=GS A0A348B0M0_9CREN/2-138   AC A0A348B0M0.1
#=GS F4BA71_ACIHW/2-139       AC F4BA71.1
#=GS A4YHZ6_METS5/2-139       AC A4YHZ6.1
#=GS A0A031LRF6_9CREN/3-140   AC A0A031LRF6.1
L0ACS7_CALLD/2-141                  ...KIIVIRSEVGKIISSELM.EGELDQIVKKKSEDAM.KEWNPETSDFIVLRDIRELELPLPL.DPELVDILRNVGT...lSRTSEKAIARIPVYTISFENMMIGEDNYVEHKIYLISPYINDDIKTELEKEAVEITTEKAAPEGI-ee........
A8ME43_CALMQ/5-142                  ..s-CVVAKIRDYAVASNEVV.NGRVFEVVKRIAVNLL.NEWNPEKGDFMILKDDRVIQIKLPLpSPELYDRLKNYNI....RRSGDSAEATVPVYEIIYSSDWVGEGFKAEEAV-LVFPFISNEINAQIINDVINTLKTGEEEMGEE..........
A0A0U3FP58_9CREN/2-138              ...KLVVISHDPDSGTNVVVL.DNELNKVVKLKALTVLeNEWNPDLGEFSVLRDNLELEYQLPL.KKEQYEVLKNFNM....RKEGKTVKVSIPYYVIMYPKYGYEGSPYV---IYLISPYLEDAIE-DLKALAQQASTGVAQ-----epqelle...
A8ABB8_IGNH4/21-154                 ..r-LVLVKYDPETGANAVVI.KGDMNEVVRQKAIAALkDEWKPESKDFMIMGDFVEFEYELPL.TPEQYEALSKYDM....RKEGKVAVVKVPYFVITFPKYAYQGSPYV---VYLVAPYLDEEKLEELKEMAEQVSEEASK-----ppe.......
G0ECK4_PYRF1/9-148                  ..p-ILVVKSVEGQIEEVKIVdDKSLTDVLREYVKKAA.DEWNPQLSDLTVMRTHYELRYKIPI.DPDLYDIVTGLGLe..lEREGNEVIVRLPVFTISYDNRWS-GDTYRDIKVYVVTYLIEDSIKDQIVEYAKETTAREKSLG---get.......
A0A550D510_9CREN/2-138              ...KILVVKSENGKVTSEKIM.EGEIGKVIREVAKSAL.DEWNEITSDFIIMHDSQEVRVPLPL.KPDVYEVLKNFLV....GKDKREAIAKIPVYIISYENEWK-ESDFQDKKVYVISYYINDDMKKEVISDATQMTSEQPKEKE--ed........
A0A510E2K8_9CREN/2-138              ...KILVLKSEDGKITSDETV.EGEIGQVVKDTANKAL.SEWNEESSDFIIIKDFHEVRIPLPL.NPKMYDVLKKFSM....SKQEKFAIVKIPSYVISFDNLWM-DNDSIDRKVYVVSYFLDDKTKQELMEDAVKLTSPEKEEKEQ-e.........
A0A2T9X2K1_9CREN/2-141              ...KVLVIRAERGKVVRDEVV.EGELKDVVKGKALEAL.NEWSPETSDFIVLKDERELELPLPL.KPELVDALRSIGS...lSRTKDKAIVRFPVYTISFENKMVSEDKYVEYKVYLLAPYINEDLKTELEAEAQDITTEKEAPEG--ire.......
E1QV18_VULDI/6-142                  .en--VVVYIENENIANKEIV.KSSLTDTVKNYVKKLL.DKWNPEESDFIVLKVPQTVSLDLPL.SKELYKKVEKYGV....RRVGNKAEVEIPTYEIIYSNRWMGEDMEADRFV-VIMPYINDNVINQVVNNILSSLTPESEGEGEE..........
A0A650CNY0_9CREN/2-142              ...KVLILRSEDGNITKKDIV.EGEFDKVLREIASSAL.KEWNETSSDFTIMRDMYEVKIPLPL.KPNVYEIIKGYLK....SRTKTEAIAEIPVYIISFDNRWM-DSDYRDMKVYVVSPYIDENVEKELTDYAIQATSQKPMNT---eeeeeee...
G4RML3_THETK/1-134                  ..m-SIVAKISQGKIVEKRIV.EGKVYDAVKREGAALL.NKWNPTSSDFIILRDYVTLSYKAPI.TKELLEKIREFSP....KRIGDKIEVTVPVFEVVYNSTWTGDNMKIDDAV-VVAPHIDDESDQRILDSVAREFAEAEEM----e.........
A0A2T9X0X9_9CREN/2-140              ...KYLVLRSELGKIVSSEDL.EGELKQVIINVAQKAM.SEWNELSSDFSIMKDTVEIVVQLPF.TKEQYVVLRNYVK....EKGQKEAVVELPVYVISFDNEWT-ESDYFDRKVYVVAPYVDSKVNGEIEQYAMQLTNPEKKGAEE-ees.......
A0A4S8RYV0_9FLAO/70-123             tgp------------------.--------------AL.NPYMEELSDYVVKKDSVQFSYEVPL.PKELIQKIAKYRL....Q-----------------------------------------------------------------dvverkakwk
Q8ZVQ1_PYRAE/1-137                  ..m-SVVAHISKNTITKKEVI.NKDVVEAVKEVAIELL.KAWDPTASDFIVLRDFYSISYPAPL.SRELLEKVRKYSP....KRVENRVEIALPVYEIVHSAQWSVEGIDVGDAV-VIFPYIDEATTEEILRGVIQSFTSPKEE----gdle......
D9PZS8_ACIS3/2-143                  ...KVLSIRAERGKVVRSEIV.DGDLKEVVKRKALEAM.NEWDPATSDFIVLKDDRELEFPLPL.KPEIVDLFRDLGElgglGRTKDKAVAHFPVYTISFENHMVSEDKYVEYKIYLLAPYINEDVRTELEAEAQDITTEKQGPEGI-e.........
A0A2U9IFK8_9CREN/2-139              ...KVLILKSETGKITSEKTI.DGNIGDVVKQVASDAL.KEWNEMTSDFTIMKDTQEARIPLPL.KPDVYEAVKSFLS....GKDKTSAILRIPIYIISFDNMWK-EDDYQDNKVYVVSYYLDDNLKNELLEYAKQATSAQKIEEQ--gee.......
Q9YAX8_AERPE/2-140                  ...KVAVIRAEHGRVEESLVF.EARLEEVVKDMARHAL.EEWDPGSSDFLVIRDDIEVTVVGDV.EEDVLKELEAQGR...vEGEGGETRVLVPIYYISFDNEMIDDENYIDKRILVIAPLVYKGFKDELEAHAASMTAPPQRP----ggik......
E0SP57_IGNAA/2-138                  ...KILILRAEYGEIKEKMIS.EGDLNKILKEVIIRTL.DLWDPNKSDLIVVRHSQEITIKLPI.KKEQYDLYSQFNL....RRKGDYASFDVPLYLVSFENQWI-DNNIVDSKVFVVSPYIDDYVSEKIEELAINITSPENEKEGEE..........
A0A830GZT4_9CREN/10-148             ..e-SIIIYVENNNVSKKETA.KGDTASVVKDLAKKLI.EEWDPNASDFIVLKDQYPIKLPLPL.SKELMDKLSRFDI....KRVGNEAEASLPVYEITYSNKWEEETFKAERLI-VISPFINDEVTTQITDAVINALNEEGEGEEQ-ege.......
A0A0V8RWB4_PYROC/2-140              ...KILVIRSDEGKLTRSDVV.EGDFNTVAKDIVRKAL.EEWHPSESDLTALRTKFELRYKLPI.DPDLYDKLVELNLe..lMREGNELVVNLPVLTISFDNAWL-EDAYLDRRMYVISYYLDEAAKRQLEEYAIEATKEPKKMG---gea.......
Q4J8M9_SULAC/2-138                  ...KILVLRSEEGNISKKEVV.DGGLRNILVKIANDAL.GEWDERSSDFTIIKDTQEVKIPLPL.KPQLYEIIKDFLK....SRTKTEAIAEIPVYIISFDNQWV-ESDYRDKKVYIVSPYIDENAEKELEDYAKQVTSLERPEPT--ep........
Q971C6_SULTO/2-138                  ...KVLVVKSENGQVSKKDIV.EGDLPQVLRNTATLAL.KEWNENLSDFIIMKDMYEIHIPLPL.KPQTYEMLKNYIK....SRTKSEAIAEIPIFVISFDNEWV-ESDFKDKKVYVVSPYIDDKSENELLEYAKQVTSPVQETETEE..........
Q7LXU9_SACS2/2-138                  ...KILIVKSENGKVTSEKVA.EGEISKVLRDVAKEAL.EEWNELASDFIIMRDNQEVRLPLPL.KPEVYEAIKTFLI....GKDKKEAIAKIPVYIISYENEWK-ESDFQDKKIYVVSFYINDEIKKDVLNDAAQMTSEQKQEELK-e.........
I0A1Y9_FERFK/7-146                  .sf--IIINAHSGKVKDKKIV.EGEFEEVVKNAGKEFLlNEWLPSFSDFMILRDIFEVELKSSL.PKEVISKYKEYNL...kRKDKDTLVATLPVYLIVYESLKISEDSYHDRGVSVVAPYIREEDAQLLSELLIETTKKPTLEEIE-k.........
W7KPG5_9CREN/2-138                  ...KVIVLKSELGKITSERSV.EGNIGEVVKQVAAEAL.KEWNEIASDFTIMKDVQEVRIPLPL.KPDVYESLKSFLS....GKDKTAAIARIPVYIISYDNAWK-EDNYQDNRVYVVSYYIDENLKNELVEYAKQATSEIKEDSG--eg........
A2BM94_HYPBU/3-142                  ...KVLVIRAEEGKIVSSDIL.DGDFAKIAKDVTARAL.TEWNPEESDLTALRTKLELRYPKPL.PPEIADKILELSLk..ySLEGNDVIVNLPVLVVSFDNRWIDETTYLDKKIYVIALYLDDNAKKQLEEYAAEATKAPKSVE---alt.......
A0A2T9WWQ5_9CREN/6-142              .en--VVVYVEGESIANKEVV.KANLVDTVKNYVKRLL.DRWNPEESDFIVLKVPQTINLDLPL.SKDLYKKVEKYGV....KRVGNKAEVEIPTYEIIYSNRWMGEDMEADKFV-VIMPYINDDIINQVINNILSSLSPEGEE----flee......
H2C9G7_9CREN/2-139                  ...KVLVLKSESGKVTSDYLE.DGNIGEVVRKTAEKAL.KEWNEFSSDFIIMRDSQEAKLPLPL.KPDLYEKVKNFLS....GKDKTSAILKLPVFIISFDNQWK-EENFQDKKVYVVSYYVTEELKKELIDYASEVTSEEKLEETEEe.........
A0A348B0M0_9CREN/2-138              ...KILLLKSERGRVTSEQLM.EGELRAAVTSVAKKAL.EEWDVDKSDFVILKDVHEIRKKLPL.SPSLYEVISKYLK....GKEQGEALAEVPVYIISFDNDWE-EEDFKDRSVYLIAPYLDEESKNEMKEYAEELTIEETEETD--ed........
F4BA71_ACIHW/2-139                  ...KVIILKSENGKITSEKIT.EGDLAEVVRNTAIEAL.KEWNELTSDFIIMKDSQEAKLPLPL.KPDVYEAVKNFLA....GKEKSAAILKIPIFIISYDNIWQ-EENFQDKRVYVVSYYLNDDLKKELIEYAQGVTSEEKPQD---sgee......
A4YHZ6_METS5/2-139                  ...KIVVLKSESGKVTSDALE.EGEIGDVVRKTAEKAL.KEWNELTSDFIIMRDSQEARIPLPL.KPDMYEKMKNFLT....GKDKTSAIVKLPIFIISFENQWK-EENFQDKKVYVISYYLNEELKKELTDYAAQVTSEEAEKEEE-ie........
A0A031LRF6_9CREN/3-140              ..s-VIVLRSESGKVTSEKVI.EGDIGDVVRNTAAQAL.KEWNDMISDFIIMKDSQEWRVPLPL.KPNDYERLKNFLS....GKEKNEAILKLPIYIISFDNQWS-GEDFQDKKVYVVSYYLDDEMKKELTTYAIDVTSENKGEN---egee......
#=GC seq_cons                       ...KllVl+uEpGclspccll.-G-lscVV+phAtcAL.cEWN.ppSDFllh+DphElclsLPL.pP-lY-tl+pahh....p+ptscAlsclPlYhISa-NpWh.EssahDc+VYVlu.Yls-phcp-lhchAhpsTopppptp...t.........
//