#=GF ID   DUF2379
#=GF AC   PF09543.14
#=GF DE   Protein of unknown function (DUF2379)
#=GF PI   CHP02267_MYXXA; 
#=GF AU   TIGRFAMs;
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   TIGRFAMs
#=GF GA   21.10 21.10;
#=GF TC   21.10 21.10;
#=GF NC   21.00 21.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR011753;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of at least 7 paralogs in Myxococcus
#=GF CC   xanthus and 6 in Stigmatella aurantiaca, both members of the
#=GF CC   Deltaproteobacteria. The function is unknown.
#=GF SQ   56
#=GS E3FXL1_STIAD/16-45        AC E3FXL1.1
#=GS Q1CVP2_MYXXD/3-120        AC Q1CVP2.1
#=GS S9P584_9DELT/5-124        AC S9P584.1
#=GS Q08ZZ2_STIAD/3-122        AC Q08ZZ2.1
#=GS A0A2T4V5T2_VITXG/3-122    AC A0A2T4V5T2.1
#=GS A0A372IQW0_9BACT/842-914  AC A0A372IQW0.1
#=GS E3FXL1_STIAD/60-121       AC E3FXL1.1
#=GS S9P584_9DELT/139-257      AC S9P584.1
#=GS A0A085WB91_9DELT/1-24     AC A0A085WB91.1
#=GS A0A7L1S883_9PASS/29-109   AC A0A7L1S883.1
#=GS S9PPJ9_9DELT/1-25         AC S9PPJ9.1
#=GS H8MSI2_CORCM/2-119        AC H8MSI2.1
#=GS Q1DEQ5_MYXXD/28-73        AC Q1DEQ5.1
#=GS A0A7K8F3Q0_9CORV/34-123   AC A0A7K8F3Q0.1
#=GS Q095I1_STIAD/12-58        AC Q095I1.1
#=GS Q092A5_STIAD/3-122        AC Q092A5.1
#=GS A0A085VSV3_9DELT/16-60    AC A0A085VSV3.1
#=GS A0A250ISF4_9DELT/3-122    AC A0A250ISF4.1
#=GS A0A2T4V5V0_VITXG/137-255  AC A0A2T4V5V0.1
#=GS Q1D3W7_MYXXD/3-122        AC Q1D3W7.1
#=GS S9R5F4_9DELT/3-122        AC S9R5F4.1
#=GS A0A250IKQ9_9DELT/1-93     AC A0A250IKQ9.1
#=GS E3FJH0_STIAD/3-110        AC E3FJH0.1
#=GS Q1D474_MYXXD/3-122        AC Q1D474.1
#=GS Q1DD95_MYXXD/3-121        AC Q1DD95.1
#=GS Q08MI9_STIAD/3-119        AC Q08MI9.1
#=GS A0A2T4V5T2_VITXG/137-255  AC A0A2T4V5T2.1
#=GS Q09BJ1_STIAD/137-255      AC Q09BJ1.1
#=GS A0A085WJ94_9DELT/3-119    AC A0A085WJ94.1
#=GS Q096M2_STIAD/137-255      AC Q096M2.1
#=GS A0A085W5L8_9DELT/9-126    AC A0A085W5L8.1
#=GS E3FQS4_STIAD/1-58         AC E3FQS4.1
#=GS A0A7T5E1X6_9CYAN/74-148   AC A0A7T5E1X6.1
#=GS A0A821P7P6_9BILA/54-135   AC A0A821P7P6.1
#=GS H8MRV6_CORCM/3-120        AC H8MRV6.1
#=GS Q1DE90_MYXXD/3-122        AC Q1DE90.1
#=GS Q09BJ1_STIAD/3-122        AC Q09BJ1.1
#=GS Q092A5_STIAD/137-255      AC Q092A5.1
#=GS A0A085WEF6_9DELT/1-105    AC A0A085WEF6.1
#=GS A0A085WEF6_9DELT/120-238  AC A0A085WEF6.1
#=GS G8EXI6_9CAUD/1-67         AC G8EXI6.1
#=GS E3FPV8_STIAD/3-122        AC E3FPV8.1
#=GS Q1DEQ4_MYXXD/3-121        AC Q1DEQ4.1
#=GS Q098Z5_STIAD/3-122        AC Q098Z5.1
#=GS Q1D470_MYXXD/3-122        AC Q1D470.1
#=GS A0A085WB91_9DELT/39-157   AC A0A085WB91.1
#=GS A0A2T4V5V0_VITXG/3-122    AC A0A2T4V5V0.1
#=GS A0A7K5Q6M0_9CORV/33-144   AC A0A7K5Q6M0.1
#=GS Q096M2_STIAD/3-122        AC Q096M2.1
#=GS H8MPM3_CORCM/1-61         AC H8MPM3.1
#=GS Q1DB37_MYXXD/43-162       AC Q1DB37.1
#=GS H8N0K3_CORCM/5-123        AC H8N0K3.1
#=GS S9PD84_9DELT/1-61         AC S9PD84.1
#=GS S9R5F4_9DELT/137-255      AC S9R5F4.1
#=GS Q098Z5_STIAD/137-255      AC Q098Z5.1
#=GS A0A250ISF4_9DELT/137-255  AC A0A250ISF4.1
E3FXL1_STIAD/16-45                   .........rehvk---------------.-----------------------------------..------..-------------------.-----.-.---.-----------SSRRVLAV..EVVPLYRRHAKNALASL.................
Q1CVP2_MYXXD/3-120                   .............d-SPDWDPVRALAHGV.LNQGIPLELTDDVRSLLRRTAREVAIS--DADTAL..QTQAGA..TELLREAMRRIKDGSWRLM.RALHR.M.YQH.KRAGDFDSARQEMREVLAE..EVVPFYRDVAAGQLEDL.................
S9P584_9DELT/5-124                   ............er--LVWRRFEQLEQRV.LEQGEALELSDETRALLSGGARLVTISTGDIEDAL..RGVSTA..TTLLREIGRRIRDGSLRLG.KVDSQ.V.DAL.RDKGDFAGARKVIEDALAA..EVVSHYREQLEIRLD--yl...............
Q08ZZ2_STIAD/3-122                   .............e-TVDWGPIRTLARRV.PIGEERLALTTAEKALLKRTASEVGISDGEAETAL..ATDEGA..VGLLREEVRRIREGSQRLM.DALTR.M.YQH.LRKEDPASARKEMRDVLAV..EVVPHYRAIAQEQLDEM.................
A0A2T4V5T2_VITXG/3-122               .............e-ETDWEELQTLAQDV.FESGAPLELSSETRALLARTARQVAISQQDAEDAL..RSLPTA..TTLLREIRQRIRDGSHRLG.DALDQ.A.GKL.QKKGDLDRAHQVMRDLLAV..EVVPLYREHAEVQLEEL.................
A0A372IQW0_9BACT/842-914             .......neaaqvl---------------.-------------------------------EAAL..ATTSDAslQQLLEKAREREKEGGRRIL.AASER.V.SEL.IDAGQYDDALRAIEAV---..-----------------trqfgvipel.......
E3FXL1_STIAD/60-121                  ..........kpse----HSQLLILLHRLdLDQGKPLNLTLGMRAFLRHAASEVAISKAETKEAL..ASPDT-..-------------------.-----.-.---.-------------------..-----------------ddlert...........
S9P584_9DELT/139-257                 ...........dfh---PWGQIRALALRV.-QQGQSLELRDDLRDFLRRTAPIVAISETETEESL..RTVGGT..EALLAVMLKRMDDGKQRLS.QALHR.M.IRC.QEAGDLEGARHQLRAVLAV..EIVPQYRRMAEENLRSL.................
A0A085WB91_9DELT/1-24                ..............---------------.-----------------------------------..------..-------------------.-----.-.---.------------MEKVLAV..EVVPHYRRIAESELRE-a................
A0A7L1S883_9PASS/29-109              adfkwtfyemqkda---------------.---EKAHRLQEQLNALQHKITTQDKIN-EELDNAL..QREHEA..GLLLQKYERRLQELSNRLE.L----.-.---.-------------------..-----------------hlksqdtnvs.......
S9PPJ9_9DELT/1-25                    .............m---------------.-----------------------------------..------..-------------------.-----.-.---.------------LEAVLAI..EVVPLYREQAEIALD--yv...............
H8MSI2_CORCM/2-119                   ............np--PDWSPLLDLARHV.LREDAPLTLSDDVRALLLQTAAEVAVS--DAASAL..QTDAGA..LALLRECARRITDGSNRLT.DALHR.M.WKL.QRQGDWDGARQEMRDVLAV..EVVPFYRDLATEQLDGM.................
Q1DEQ5_MYXXD/28-73                   ..........hlfg-----EQIGELNSCV.TERGALLVLCDGTRGLLRYASFEVGISPEEA----..------..-------------------.-----.-.---.-------------------..-----------------a................
A0A7K8F3Q0_9CORV/34-123              .....afdemqkha---------------.---DKAHRLQEQLNALQHRIIIQDNIH-EELNNAL..QREHEA..RLLLQEHERRLQELSNRLE.V--HT.S.ADT.DSSQDLNVAPKSLS-----..-----------------ease.............
Q095I1_STIAD/12-58                   ..........asae---------------.-----------------------------------..------..-------------------.---MRsA.WRR.AEAGDVAGARREAHRLLAS..SASPEDRAQAEELLR--rt...............
Q092A5_STIAD/3-122                   .............d-KFGSELIDELEAHV.LEDGEPLVLSDEVRALLRRSAEQVALSPGDADEAL..RSVPTA..TTLLQEISRRFKEGSKRLF.EAQVK.A.SDL.RDAGDLDGACRELEGVLSV..EVVPLYRQRAADSLHAL.................
A0A085VSV3_9DELT/16-60               ..htkcgratelgq---------------.-----------------------------------..------..-------------------.-----.-.---.---THFGSARQEMRDVLKV..EVVPHYRALAEGQLEDM.................
A0A250ISF4_9DELT/3-122               ..............DEIDWNSIRELSRRV.LERGESLELTEGTRALLLRTAQEVGISHEDAGEAL..RNGSTA..STLLRETITRIDDGSDRLS.DARLR.M.YDL.RDAGDLEGARQQMRDVLAV..EVVPLYREQAGILLDEL.................
A0A2T4V5V0_VITXG/137-255             ............dl--PDRDQLAVLSQRI.-QQGNALELTDDLRALLRRVAPTAAVSEAETEEAI..KSPEGA..EALMGMILSRFQKGGRRFL.RAMYQ.M.TSL.RDAGDLEGARQQMRDVLAV..EVVPRYRQAAEEQLRGL.................
Q1D3W7_MYXXD/3-122                   ............eh--RTWHEIRELNRRV.TDLGEPLVLTDENRALLTNTASEVAITPREVTQAL..QDDVSA..AALLKEIAKRIRVGSRRLS.RAITE.A.IKH.QEAGDLDAARAPFLELLNV..EVVPFYRELAQVQLDAL.................
S9R5F4_9DELT/3-122                   .............a-KINWDSIRALARRV.IEHGNPLELTEDTRALLRRTAQEVGISQQETEDAL..RGVNTA..TTLLKEAMRRINDGSDRIT.RALRR.M.SDL.RDKGDLDGACQQMRDVLAV..EVVPLYRKQADKRLKEL.................
A0A250IKQ9_9DELT/1-93                ..............---------------.------------MRALLRRTAPTAAINEAETEEAL..KSPEGA..EALMGMVLSRFRESARRFL.NSMYR.M.TSL.RDSGDIEGACQQMCDVLAV..EVVPRFRQAAEEQLKGL.................
E3FJH0_STIAD/3-110                   .............e-TVDWGPIRTLARRV.PLGEERLALTMTEKALLKRTASEVGLSDGEAETAL..ASEEGA..LGLLREEVRRIREGSRRLM.EALAR.I.YRH.QDKGDVSSARQERREVLAV..EVVPH------------.................
Q1D474_MYXXD/3-122                   .............e-KIDWDPIRALARRV.IREGAPLVLDDDVRALLRRTAREVGISDANAEQAL..STEVGA..LELLRESSRRITDGSNRLM.DALHR.M.YRH.QKAGDFDSARQEMRDVLSV..EVVPHYREVAEGQLEDL.................
Q1DD95_MYXXD/3-121                   .............e-SIDWDPVRELARRV.-EAGEALSLTAEVRALLLRSAREVGIPEEDAHAAV..AGVATA..TALLHETRRRIRDGSQRLM.RALTG.A.RRL.RDAGDAAGARALLEDVLAV..EQVPLYREQAELALEDM.................
Q08MI9_STIAD/3-119                   ..............DQPDWGPFRSLSRRI.LQEKVPLTLTEDVRALLLRTAREVAIP--DAEATL..STEAGA..LALISEAERRISDGSNRLT.DALHR.M.WRL.QESGDFDGARQEMSEVLAV..EVVPYYRMLAQEQLD--r................
A0A2T4V5T2_VITXG/137-255             ............dl--PDRPQLAVLAQRI.-QQGHALALTDDIRALLRRIAPTAAVSETETEEAL..KSPEGA..EALMEMILSRFQKGERRFL.RSMYR.M.TSL.RDAGDLEGARQQMRDVLAV..EVVPLYREMAEEQLRGL.................
Q09BJ1_STIAD/137-255                 ............kl--SDRAQAPILLHRV.-QQGHPLELNEGMRAFLRRSASDAGMSEAETEEAL..AIPERA..GTLLGQIMQRLRDASDRLE.SAMYR.M.TEL.QDAGDVEGARQQIRDWLAV..EVVPRFRRAAEEQLT--yl...............
A0A085WJ94_9DELT/3-119               .............e-QHDWDKVREWEKRL.-DQDQ--VLAPDVTDLIRRVARDVAIPEEEAQRAV..GTPIAA..TMLLREMSRRIREGSRRLM.RAISE.A.NRR.KEAGDAAGARKILEEVLAA..EIVPLYRQHVEAELS--yl...............
Q096M2_STIAD/137-255                 ............kl--SERSQLASLLYRI.-NQGKPLKLTKEMRSFLRLAAAEAAISEAETEEAL..ASPTSA..AALVRKTLGRLRNGSKRLE.HAISR.M.LDL.REVGDLEGARQQMRDLLAV..ETVPMYRRAAEENLAGL.................
A0A085W5L8_9DELT/9-126               ...........dal----WNQLWELEQLV.-HRGGDLELTGDVRNLLLRAAPTVALGEAEAMAAL..LSVEGA..IELLGKIRARVREGSHRLG.NALHR.M.YRL.QEQGKLDEARQQMRDLLSV..EVVPLYREIAEGELEKM.................
E3FQS4_STIAD/1-58                    ..............---------------.-----------------------------------..------..------MRARILDGSHRLS.DVLRP.M.YCL.RDSGELDAARHQRRDLLAV..EAVPLYRDTAEGQR---dpl..............
A0A7T5E1X6_9CYAN/74-148              .........segvs---------------.---------------------------TGDPAAYLqeQSTRTA..DSLLSVTDARIANSSNGLI.KTTYQ.R.LRQ.SVKGDVEAAVPGLAKILAT..HAV--------------qalp.............
A0A821P7P6_9BILA/54-135              .........silyh---------------.---------------------------KGDINRAL..QCATRA..VELLRQC----TNGDPRLA.AALNN.L.GALhQANGDFVKARQHFEEALAClhDTTHPYRTSTANNIAR-l................
H8MRV6_CORCM/3-120                   .............t-RPDWDSIRALSRRV.LREGALLTLTDDVGALLLHTADEVAIP--DAATAL..QTDAGA..LALLRECARRITDGSNRLV.DALYR.M.HRL.QDAGDWEGARQEMRAVLAV..EVVPFYRETAQGQLDDM.................
Q1DE90_MYXXD/3-122                   .............e-ELDWDPIRALARRV.LRNGEPLMLTIEVRELLARTAREVGLSQADATSAL..ASDTSA..LELLRECSRRISEGSSRMV.NALHR.M.YQH.KRAGDLDSARQEMRDVLAA..EEVPHYRAVAQGQLN--ll...............
Q09BJ1_STIAD/3-122                   .............t-EIDWGPIRALGQRV.IERGEPLELTDEVRALLQRSAEEVALAPEDAQNAL..RSIPTA..TTLLGEIRRRIREGSAQLG.AATLR.A.YDL.RDDGDLDSACRQMEEVLAV..EVVPLYREHAEAMLREM.................
Q092A5_STIAD/137-255                 ...........tlr---DRSQLPILLHRV.-QQGHPLDLNEGMRAFLRRAAADVGMSEDETEPAL..ASPESA..GALLGQIMGRLRDASGRLE.SAMYR.M.TER.RDAGDLEGARQQIRDWLAV..EVVPRFRRAAEEQLAGL.................
A0A085WEF6_9DELT/1-105               .............m---------------.-ERGEPLELTGNVRTLLRRSAREVAIPTEDVKQAL..RNPRTA..TALLRKIRQRINAGSHRFG.SAQSR.A.YRL.RDAGNLDGARKAMEAVIAV..EVVPFYRELAANVISN-l................
A0A085WEF6_9DELT/120-238             ...........klp---ERSQTLVLLRRV.-QQGRPLKLSNGMRAFLRRAAAEVGISKAEAKEAL..TSPQSA..GALLEKIMRRFHEGRKRLE.RALMR.M.MDF.RDAGDLEGARQQMRDLLAV..EVVPMYRRAAEENLEGL.................
G8EXI6_9CAUD/1-67                    .........mieav---------------.------------------------------VSATL..AALAAG..AALTNRIHNRINDMDQRLD.TFELR.VaTQY.VPKQDFDTAMQKMEDH---..-----------------miriet...........
E3FPV8_STIAD/3-122                   .............d-ALNWDDVRELAKRV.FDAGELLLLSDEVLVILRRTAREVAIDAEEAEQAL..RTVPEA..TVLLGKMARRIRDGSHRLS.RALVQ.M.HRL.RDAGDLEGARQQMREVLAV..EGVPHYREIVEGQLAEM.................
Q1DEQ4_MYXXD/3-121                   .............d-ELEWEPVRALARRV.-REGERLTLTAEVREMLERTAPEVGIGKADAAAAL..ATAEKA..EALLLECARRIKEGSDRIV.DALYR.A.KRH.RKAGDFDSARQEMREVLAI..EVVPLYREIAEGQLEDM.................
Q098Z5_STIAD/3-122                   .............a-ELDWEPIRALGQRV.IERGEPLELSDEVRALLQRSAEEVALSPEDTANAL..RSVPTA..TTLLEEITRRIREGSDRFW.NAELR.A.SDL.QDAGDLDGAGRLMEEVLAV..EVVPHYRRIAESQLRK-v................
Q1D470_MYXXD/3-122                   .............k-TLDWNPIRALARRV.LREGQPLVLSDEVRALLLRSAREVAIRDADVGRAL..ATDVDA..LKLLEAISDRIRKGSLRLS.RTLSE.A.VRR.RDAGDVDGARQLLHDALAV..EVVPIYRDS--------lyayvesl.........
A0A085WB91_9DELT/39-157              ............kl--SDRAQLPILLHRV.-QRGQPLELNEGMRAFLRRSAADVGMSEAETEPAL..ASPEIA..GVLLGQIMGRLRDASDRLK.SAMYR.M.TEL.RDAGDLAGARQQIRDWLAV..EVVPRYRRAAEEHLAHL.................
A0A2T4V5V0_VITXG/3-122               .............e-EVDLDDVWVLCRDV.LENGAPLELNDEMRTLLSRTAQQVAIGQQDAQDAL..RSLSTA..MTLLREIHQRIGEGSRRLS.RARNR.A.YEL.RDKGDLEGACQQIRDVLAV..EVVPLYRKHAEVQLEKL.................
A0A7K5Q6M0_9CORV/33-144              ....wtfsemqkda---------------.---EKAHKLQEQLNALQHKIITQDNIN-EELDNAL..QREREA..RLLLQEYERRLQELSNRLElHSRAD.A.YRS.QDSNAEKSVSNAMEELRRR..-----------------eevlnhhkrllkdleqd
Q096M2_STIAD/3-122                   .............g-KTDWAPIEALAQRV.LEQGEPLELTADVRTLLRRSAREVAIPAQDVQQAL..RSLRTA..KPLLRKIRKRIEDGSWRLM.LAEHR.A.RRL.QDAGDLEGARRQIERVLTV..EVVPFYRQQAENVLAR-i................
H8MPM3_CORCM/1-61                    ..............---------------.-----------------------------------..------..---MREAERRIAEGSNRLT.DALHR.M.WSF.QRQGDFDSARQQMRDVLAV..EVVPYYRELALEQLSGM.................
Q1DB37_MYXXD/43-162                  .............k-TIDWGPIRTLARRV.LTEGERVALTRKEKALLRRTAAEVGISASEVESAL..ATEEGA..LGLLQEESRRISEGTRRLM.DALHR.M.YEH.KDKGDLDSARQEMRNVLAV..EVVPHYRAIAQGQLEAM.................
H8N0K3_CORCM/5-123                   ............le--GDWHQLRVLDTRA.QQEGT-VVLDDALRTLLRRTGPSVAMTTAEVDAGL..HTPEAA..RTLLHQMRQRVTEGSRRLG.DALHR.M.YRL.RDQGDLDGARQQMRDLLAV..EVVPYYRELAQGQLADL.................
S9PD84_9DELT/1-61                    ..............---------------.-----------------------------------..------..---MREMRHRIFEGSRRLS.RALVD.S.ARR.KKAGDVAGARAVLEGVLAV..EVVPLYREQAETALS--yv...............
S9R5F4_9DELT/137-255                 ............dl--PDRPQLAVLAHRV.-QQGHALELTDDLRALLHRTAPTAGISEVETEEAL..KSTGGA..EALMGMILSRFRDGRERIT.RALFR.M.TSL.RDAGDLEGARQQLRDVLAV..EVVPIYREMAEENLAGL.................
Q098Z5_STIAD/137-255                 ...........kls---VREQIPVLLHRV.-QRGHPLELNEGMRAFLRRAAADVGMSEAETEPAL..ATPESA..GALLGQIMGRYRDASDRLK.SAMYR.M.TEL.QDAGDLEGARQQIRAWLAV..EVVPRYRRAAEENLAGL.................
A0A250ISF4_9DELT/137-255             ..........dlpa----RPQLAVLAQRI.-QQGHALELTDNLRALLRRTAPTAAVSEAETEEAL..KSTEGA..EALMVMILSRFQKAEHRFL.RSMYR.M.TSL.RDAGNLEGARQQMRDVLAV..EIVPQYRRMAEEQLKGL.................
#=GC seq_cons                        .............t....ht.l..L.p+l..ppGpsLtLspthRuLLpRsA.pVulstt-sppAL..tostsA..tsLLpchhpRlp-GSpRL..pAhhR.h.hch.p-sGDl-uARpphc-VLAV..EVVPhYRchAptpLpt..................
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