#=GF ID   DUF2551
#=GF AC   PF10826.12
#=GF DE   Protein of unknown function (DUF2551) 
#=GF AU   Pollington J;0000-0002-8158-8998
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   PRODOM
#=GF GA   23.40 23.40;
#=GF TC   24.60 23.40;
#=GF NC   22.80 21.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0123
#=GF DR   INTERPRO; IPR020501;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This Archaeal family of proteins has no known function.
#=GF SQ   57
#=GS B8GGW4_METPE/15-97       AC B8GGW4.1
#=GS D5EC40_METMS/13-94       AC D5EC40.1
#=GS Q8PSX3_METMA/12-94       AC Q8PSX3.1
#=GS E1RHR3_METP4/15-97       AC E1RHR3.1
#=GS D3S060_FERPA/9-89        AC D3S060.1
#=GS L0HH18_METFS/15-96       AC L0HH18.1
#=GS Q12YF4_METBU/12-94       AC Q12YF4.1
#=GS F4BU21_METSG/12-94       AC F4BU21.1
#=GS D7E910_METEZ/12-94       AC D7E910.1
#=GS A0A2V2N4W6_9EURY/22-104  AC A0A2V2N4W6.1
#=GS Q12ZR1_METBU/15-96       AC Q12ZR1.1
#=GS D7E633_METEZ/12-94       AC D7E633.1
#=GS Q0W0E8_METAR/6-87        AC Q0W0E8.1
#=GS D1YZL8_METPS/6-87        AC D1YZL8.1
#=GS D2RGY3_ARCPA/9-89        AC D2RGY3.1
#=GS Q2FUK9_METHJ/14-96       AC Q2FUK9.1
#=GS L0L181_METHD/15-96       AC L0L181.1
#=GS A0A0E3NWG4_9EURY/12-94   AC A0A0E3NWG4.1
#=GS A0A8J7RBY2_9EURY/15-97   AC A0A8J7RBY2.1
#=GS A0A483CSD0_9EURY/15-97   AC A0A483CSD0.1
#=GS W9E1I1_METTI/12-94       AC W9E1I1.1
#=GS A0B546_METTP/12-93       AC A0B546.1
#=GS A0A0F7IJZ7_9EURY/10-90   AC A0A0F7IJZ7.1
#=GS A0A062V5G6_9EURY/12-94   AC A0A062V5G6.1
#=GS W9DZ90_METTI/19-100      AC W9DZ90.1
#=GS A0A484F3E8_9EURY/11-93   AC A0A484F3E8.1
#=GS A0A484F4W0_9EURY/15-96   AC A0A484F4W0.1
#=GS Y1218_ARCFU/9-89         AC O29050.1
#=GS G7WM51_METH6/12-94       AC G7WM51.1
#=GS A0A1F2P721_9EURY/16-97   AC A0A1F2P721.1
#=GS F4C0L5_METSG/12-93       AC F4C0L5.1
#=GS A0A498H0K5_9EURY/15-97   AC A0A498H0K5.1
#=GS A0A062VAI0_9EURY/1-77    AC A0A062VAI0.1
#=GS Q0W312_METAR/12-95       AC Q0W312.1
#=GS A7I9A0_METB6/15-96       AC A7I9A0.1
#=GS A0A0X3BNY4_9EURY/15-97   AC A0A0X3BNY4.1
#=GS N0BC27_9EURY/31-111      AC N0BC27.1
#=GS D1YWB1_METPS/12-95       AC D1YWB1.1
#=GS A0A4E0PVI2_9EURY/12-94   AC A0A4E0PVI2.1
#=GS D7E8Q1_METEZ/15-96       AC D7E8Q1.1
#=GS A2SPP7_METLZ/15-97       AC A2SPP7.1
#=GS G7WQR4_METH6/16-97       AC G7WQR4.1
#=GS F7XLC7_METZD/12-94       AC F7XLC7.1
#=GS Q8TNA4_METAC/22-104      AC Q8TNA4.1
#=GS I7J9W8_METBM/15-97       AC I7J9W8.1
#=GS Q8PZ77_METMA/1-82        AC Q8PZ77.1
#=GS L0KZI5_METHD/12-94       AC L0KZI5.1
#=GS A0A1F2P8I2_9EURY/15-96   AC A0A1F2P8I2.1
#=GS F2KN66_ARCVS/10-88       AC F2KN66.1
#=GS A0A8J8B4T4_9EURY/15-97   AC A0A8J8B4T4.1
#=GS H1YXW4_9EURY/15-97       AC H1YXW4.1
#=GS Q8TJQ8_METAC/1-82        AC Q8TJQ8.1
#=GS A0A0E3L614_9EURY/1-82    AC A0A0E3L614.1
#=GS F7XMM5_METZD/13-94       AC F7XMM5.1
#=GS A0A2V3JNB8_9EURY/12-94   AC A0A2V3JNB8.1
#=GS A0A4E0Q957_9EURY/12-93   AC A0A4E0Q957.1
#=GS D5EBG2_METMS/12-94       AC D5EBG2.1
B8GGW4_METPE/15-97                  .......LRGYLSRDHTGIRRELLNLFVRIKSLTVPLIFEEMQQH.YAITYHSIASMVGTIASRIGILHVRKPIEGNNCVYELKEKYLDLV..............
D5EC40_METMS/13-94                  .......LIKYLGRDDTGIRKVVLKLFLDGGKYTTNDIYKFLHEKdFDISYRGVSAMVGLMNTRLGILSI--DVTGDHNIYLLKNDYRDIV..............
Q8PSX3_METMA/12-94                  .......LEKFLEVDSNGYRRAILCIFIKVKKATIDELHEMLSSK.YNVSRNTVASMVGYIHSKLGILRAHKESYKTPMVYLLREEYIDLI..............
E1RHR3_METP4/15-97                  .......LRNYLSRDKNGIRRELLKIFVRAKSLTVAETHKKLMEK.FSVTVQSVASMVGTIASRIGIFHIIKEKDNDQTRYELKEQYADLV..............
D3S060_FERPA/9-89                   .......LRKYLERDRSGIRRALLKIVLSGEKLTTEEIQKRLAEMgYNLNIRGVSAMVGLMSARLGILKL---EIGEKNKYYLKKEYESVV..............
L0HH18_METFS/15-96                  .......LRSYLSRDRTGIRREVLRLFVKSKAITIAELVAILQKQ.FTVTFHAIASMVGIIASRIGILRATRNSDGVNS-YELKEKYVDIV..............
Q12YF4_METBU/12-94                  .......LNKFIELDVNGFRSYVLSVFLSVKKSTIDELHQAIAKK.YDVSRSAVASMVGYIHSKLGILRSHKESYKTPIVYSLKEEYADL-l.............
F4BU21_METSG/12-94                  ......m-MNFLDLDSDGLRRVVLESMVQSQEFTVLSLHEEVSKE.VNVSRKVVASMTGYIGSRLGILHMNKKSYRTPRTYALKDEYADI-a.............
D7E910_METEZ/12-94                  .......LQKFVELDTSGLRSSVLSFFLKEKNVTVDDLYEAIKTK.FNISRSSVASMVGYIHSKLGILRAYKESYKTHMVYTLKDEYVDLI..............
A0A2V2N4W6_9EURY/22-104             .......LRSWLAGDDEGIRYAMLRIFLNHNDLSIQEIYEKLSLS.FRTSYHSVSGMIGIVSSRIGILVGTRSDRDRCRIYRLREKHTPIV..............
Q12ZR1_METBU/15-96                  .......LIKYLGRDDTGIREVVLKMFLDGGTFTTSDVYKHLHEKeFDVSYRGVSAMVGLMNTRLGILSI--DVTGDHNLYLLKEDYKPVV..............
D7E633_METEZ/12-94                  .......LQKFIEKDEDGVRSNILCVFLNKNKLTIDDLYSIITTK.YNISRNSVASMVGYIQSKLGIIQSYKKDYKSPTVYYLKDKYAFI-i.............
Q0W0E8_METAR/6-87                   .......IKDYLSRDKDGRRRAVLEMFLENGPYETKDIDDRLREKnFDVKNKGTPAMVGLMGSKTGILSV--DVTGDHNVYSIKEKYKHLV..............
D1YZL8_METPS/6-87                   .......IKDYLSRDKDGRRRAVLRIFLDGGPYETKDIDEKLREQnFDVKNKGTPAMVGLMGSKTGILSV--DVTGDHNMYSIKEKYKRLV..............
D2RGY3_ARCPA/9-89                   .......LVNYLKRDKKGIRREVLSIMIDGRKYTTSEIYEILKAKgYDVNLRGVSAMLGLMNTRLGIVRT---ETGEKNRYYIKPEYIELV..............
Q2FUK9_METHJ/14-96                  .......LKAWLSGDPNGVRRAALSLFLQYGDLTIEDVYERLAPV.YPVSYHGVGGMIGLISSRIGILQGIRDDKRRCRSYRLREKDRAS-v.............
L0L181_METHD/15-96                  .......LIKYLSRDDTGIRKVVLQLFLEGDKFTTGDVYGYLNKTdFNVSYRGVSAMVGLMNTRLGILSI--DVTGDHNIYLLKEDYRDVV..............
A0A0E3NWG4_9EURY/12-94              ......v-EKFIEVDSTGYRRAILCIFIKVKKATIDELHEMLGKK.YNVSRNTVASMVGYIHSKLGILRSHKESYKTPMVYTLREEYLDL-l.............
A0A8J7RBY2_9EURY/15-97              .......LKKYLSRDNTGIRHELLSFFVKMKTTTIPEIYEKISES.FEISYHSVASMVGIIASRIGVLHVKRDPEGPNAVYEIKDAYVGMV..............
A0A483CSD0_9EURY/15-97              .......LKKYLSRDNTGIRHEVLSLFVRVRSTTIPEIHAQVSRT.FSVSYHSIASMVGIIAARIGILHVRREQEGTNAVYQIKDEYIGMV..............
W9E1I1_METTI/12-94                  .......LQKFIELDVNGLRSHILSIFLSVKETTVDELHANITEK.YDISRSAVASMVGYIYSKLGVLRSHKESYKTPIVYSLKEEYEDMI..............
A0B546_METTP/12-93                  .......LRNYLKRDGIGIRKAVLKLFLSDSSFTTEDIFTHLEKEgFNVSYRGVSAMVGLMNTRLGILSI--DVSGDHNVYSLKNDHKMIV..............
A0A0F7IJZ7_9EURY/10-90              .......LRKYLERDRSGIRKTLIGILLDGNKYTTEELHRKLSENgYELNPRGVSAMVGLMSARLGILKV---EMGEKNRYYLKKEYEGLV..............
A0A062V5G6_9EURY/12-94              .......LEVYLELDIDGVRKFIINVLLKLKKVTVDQLYRELNMR.FKISYSAVASMLGYIHSKLGILHACKESYKTPTVYSLKEEYIEII..............
W9DZ90_METTI/19-100                 .......LIKYLSRDDTGIRKVVLKLFLNGDKFTTGDVYEHLHDTdFDVSYRGVSAMVGLMNTRLGILSI--DVTGDHNIYLLKEDYRDIV..............
A0A484F3E8_9EURY/11-93              .......LEQFIAADSTGYRKKCLDLFIKVKEFTVSQIHDLLSED.YQVTRNEVASMIGYIQSKVGILKSHKESYKTPTVYTVKDEYVALI..............
A0A484F4W0_9EURY/15-96              .......LEKYLSRDENGIRKIVLNLFITGDKFTTGDVYKHLEQEsCDVSYRGVSAMVGLMNTRLGILSI--NVTGDHNIYSLKDDYKTVV..............
Y1218_ARCFU/9-89                    .......LRKYLERDKNGLRRELLRVLLEGKKFTTSEIHDILSRRgYSISPRGVSAMVGLISARLGILKT---ELGEKNRYYLKSEYADLV..............
G7WM51_METH6/12-94                  .......LVQFLDLDTDGRRRFVLGVILEAGEITVSSLYKAVKEQ.FETSRKVVASLLGYICSKLGILSAHKKSYRLPTVYVLKEEYADLV..............
A0A1F2P721_9EURY/16-97              .......LREYLKRDGDGMRLAMMRILLDEESISTKELYERLGKKgVRRTYRGVCAALGAMNSRLGILAI--STRSGRKIYRVKPECRKLV..............
F4C0L5_METSG/12-93                  .......LRNYLKRDGVGIRKAVLKLFLSDGAYTTEDVFTYLAKEgFDVSYRGVSAMVGLMNTRLGILSI--DVSGDHNVYSLKGDHKGVV..............
A0A498H0K5_9EURY/15-97              .......LHGYLSRDRDGIRHELLNLFVKVKSLTIPQIHEKLQEH.FSISYHSVASMVGIIASRIGILHVKRNAEGTNTLYEIKDQYLEVV..............
A0A062VAI0_9EURY/1-77               ......m------RDETGIRKSVLKLFLNSKPYTTQEIFDFLIKEgFDVNYRGVSAMVGLMNTRLGILRV--DVKGDHNIYSLKNEYKNAV..............
Q0W312_METAR/12-95                  .......LDEYLKSDVSGIRRTVLHAFVKLKKLTADTLHRILIERnFAITLKQVTAMLGVIHSKLGILHAHKNSYDAKYEYSLKEKYAGIV..............
A7I9A0_METB6/15-96                  .......LKSYLHRDKTGIRREVLRLFLRFRQTTIADILEDLKGQ.FSVSFHTIASMVGIIASRIGILKVSRNSGGVTT-YELREKYAAMV..............
A0A0X3BNY4_9EURY/15-97              .......LEGYLSRDRDGIRHELLSLFVKIRSLTIPQIYEKLQEQ.FSISYHSVASMVGIIASRIGILHVRRNAEGTNTIYELKDQYVDVV..............
N0BC27_9EURY/31-111                 .......LRKYLDRDKKKVRSALLRILLSGKKYTTDEIYEELKASgVDIKMRGVSAMVGLISARLGIVKM---ELGNKNRYYLKKEYYDLV..............
D1YWB1_METPS/12-95                  .......LHDYLATDVQGIRRIVLQAFVKMKSLTADTLHRILMERgFSITLKQVTAMLGVIHSKLGILHAHKNSYDAKYEYSLKEKYEGIV..............
A0A4E0PVI2_9EURY/12-94              .......LQRFIELDVNGLRSCILSKFLDVKEATVDELHAAIKKN.YDISRSAVASMVGYIYSKLGVLRSYKESYKTPIVYSLKEQYVDLI..............
D7E8Q1_METEZ/15-96                  .......LTKYLSRDSTGIRKAVLKLFLEDDAYTTSDVYEYLRNHnFDVSYRGVSAMVGLMNTRLGILSI--DVTGDHNVYMLKEDYRQIV..............
A2SPP7_METLZ/15-97                  .......LRSYLSRDKSGIRKALLRLLIRAKSMTVPQIHEALSTK.FDVTYHSVASMVGIVASKLGILSTHKMKDGALGVYELKAQYADLV..............
G7WQR4_METH6/16-97                  .......LKNYLKRDGMGIRKAVLKLFLHDRSFTTEEVYTYLDQEgFEVSYRGVSAMVGLMNTRLGILSI--DVSGDHNVYSLKPDHKVIV..............
F7XLC7_METZD/12-94                  .......LQKFIELDVSGLRSYILSIFLNNKKVTVDDLHQAITKK.YDTSRSAVASMVGYIHSKLGILSAHKESYKTPIVYTLKEDYIDLI..............
Q8TNA4_METAC/22-104                 .......LEKFLEVDSNGYRRAILCIFIKVKKTTIDELHEMLSSR.YNVSRNTVASMVGYIHSKLGILRAHKESYKTPMVYLLREEYIDLI..............
I7J9W8_METBM/15-97                  .......LEGYLSRDRDGIRHELLSLFVKIRSLTIPQIYEKLQEQ.FSISYHSVASMVGIIASRIGILHVRRNAEGTNTIYELKDQYVDVV..............
Q8PZ77_METMA/1-82                   .......MIKYLGRDENGIRKVVLNLFLTGDKFTTGEVYDYLDKGnFEVSYRGVSAMVGLMNTRLGILSI--NVTGDHNVYSLKETYKNIV..............
L0KZI5_METHD/12-94                  .......LQTFIELDVNGLRTHILSVFLQVQKTTVDELHQSINSK.FEISRSAVASMVGYIYSKLGILRSYKESYKTPIVYSLKEEYADL-l.............
A0A1F2P8I2_9EURY/15-96              .......LKDYLKKDKTGIRLAMLDALLESEGCTTMDLHAALLDNgFDYSYRRVCAMLGAMNSKLSVLMQ--TKQGKSRIYQIKPAC----rdal..........
F2KN66_ARCVS/10-88                  .......LRKYLERDRSGIRKELLRILLEGGKYTTDEIFERLSTR.-AINQRGVSAMVGLMCARLGIIKT---ELGEKNRYYIKPEYADLV..............
A0A8J8B4T4_9EURY/15-97              .......LRAYLSRDTSGIRKELLNLFIRVRSLTIAEIHARLNEH.FSIGIKSVASMVGIIASKFGILHIRRKAESTTSVYEMKEQYLDVV..............
H1YXW4_9EURY/15-97                  .......LKNYLSRDKDGIRRELLNIFVKVKSVTVEDTHNKLKER.FAISYQSVASMIGIIASKMGILHIIKARDNDQTQYVLKDQYADLV..............
Q8TJQ8_METAC/1-82                   .......MIKYLGRDDNGIRKVVLNLFLTGDKFTTGEVYDFLDKGnFEVSYRGVSAMVGLMNTRLGILSI--NVTGDHNVYSLKESYKNIV..............
A0A0E3L614_9EURY/1-82               .......MIKYLGRDESGIRKVVLNLFLTGDKFTTGEVYEFLDSGeFEVSYRGVSAMVGLMNTRLGILSI--NVTGDHNVYSLKNTYKTIV..............
F7XMM5_METZD/13-94                  .......LIKYLGRDDTGIRKEVLKLFLEGGSFTTNDVYEQLQKRgYNVSYRGVSAMVGLMNTRLGILSI--NVTGDHNIYSLKEDYREIV..............
A0A2V3JNB8_9EURY/12-94              .......LERYLELDADGIRYAVMKTILRVKRITVDLLHDSLSKK.FKVTHKTVASMVGYIHSKLGILHAQKQSYKTHIVYTLRDEYVDLV..............
A0A4E0Q957_9EURY/12-93              .......LIKYLSRDDTGIRKVVLKLFLKGGKFTTGDVYEHLHNAdFDVSYRGVSAMVGLMNTRLGILSI--DVTGDHNIYLLKEDYRNIV..............
D5EBG2_METMS/12-94                  .......LKKFVELDVSGLRTHILSILLNVKQFTVDDLHEKINKQ.FDVSRSVVASMVGYIHSKLGILRSHKESYKTPTTYSLKEEYVDLI..............
#=GC seq_cons                       .......LccYLpRDpsGIR+tlLplFLcscphTss-lactLpcc.FslSh+uVuuMVGlhsS+LGILps..pshuspslYpLK-cYtslV..............
//