#=GF ID   DUF2623
#=GF AC   PF11115.12
#=GF DE   Protein of unknown function (DUF2623)
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   PRODOM_PD065638
#=GF GA   25.70 25.70;
#=GF TC   51.00 50.90;
#=GF NC   23.30 20.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR022574;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family is conserved in the Enterobacteriaceae family.
#=GF CC   Several members are named as YghW. The function is not known.
#=GF SQ   49
#=GS A8APN5_CITK8/1-93      AC A8APN5.1
#=GS A0A378DKK5_KLEPR/1-93  AC A0A378DKK5.1
#=GS Q7CPS7_SALTY/1-93      AC Q7CPS7.1
#=GS YGHW_ECO57/1-93        AC P64576.1
#=GS W1HZS7_KLEPN/1-93      AC W1HZS7.1
#=GS A0A0J5LSP4_PLUGE/1-93  AC A0A0J5LSP4.1
#=GS W1DFY9_KLEPN/1-93      AC W1DFY9.1
#=GS A0A2X3EA02_KLUCR/1-93  AC A0A2X3EA02.1
#=GS YGHW_ECOLI/1-93        AC P64574.1
#=GS A0A5R9LD45_9ENTR/1-93  AC A0A5R9LD45.1
#=GS A0A2I8PZY5_9ENTR/1-93  AC A0A2I8PZY5.1
#=GS A0A4P7J9L8_9ENTR/1-93  AC A0A4P7J9L8.1
#=GS Q32C64_SHIDS/1-93      AC Q32C64.1
#=GS A0A4Z0N4Q1_SALET/1-93  AC A0A4Z0N4Q1.1
#=GS A0A447LYE8_SALBN/1-93  AC A0A447LYE8.1
#=GS A0A2C6DNP5_9GAMM/1-93  AC A0A2C6DNP5.1
#=GS A0A6M8UPF9_9GAMM/1-93  AC A0A6M8UPF9.1
#=GS A0A663AI27_9ENTR/1-93  AC A0A663AI27.1
#=GS Q6DB41_PECAS/1-93      AC Q6DB41.1
#=GS A0A656YJ26_SALNE/1-95  AC A0A656YJ26.1
#=GS A6TDZ5_KLEP7/1-93      AC A6TDZ5.1
#=GS H5V3G8_ATLHE/1-92      AC H5V3G8.1
#=GS A0A248KHB0_9ENTR/1-93  AC A0A248KHB0.1
#=GS A0A377Z327_KLEPO/1-93  AC A0A377Z327.1
#=GS A0A0H3GTC7_KLEPH/1-93  AC A0A0H3GTC7.1
#=GS A0A509C250_9ENTR/1-49  AC A0A509C250.1
#=GS A9MQK4_SALAR/1-93      AC A9MQK4.1
#=GS A0A240C7Y9_SERFI/1-93  AC A0A240C7Y9.1
#=GS A0A6B2FLN3_9ENTR/1-95  AC A0A6B2FLN3.1
#=GS A0A8J7H846_9ENTR/1-93  AC A0A8J7H846.1
#=GS E3G3E8_ENTLS/1-93      AC E3G3E8.1
#=GS A0A4P8YD87_9ENTR/1-93  AC A0A4P8YD87.1
#=GS A0A443I944_9GAMM/1-93  AC A0A443I944.1
#=GS A0A509C324_9ENTR/1-51  AC A0A509C324.1
#=GS A0A370QNI3_9GAMM/1-93  AC A0A370QNI3.1
#=GS YGHW_SHIFL/1-93        AC P64577.1
#=GS A0A0L0AP69_9ENTR/1-93  AC A0A0L0AP69.1
#=GS C5BBK2_EDWI9/2-94      AC C5BBK2.1
#=GS A0A2X4TLL8_SALER/1-93  AC A0A2X4TLL8.1
#=GS A0A5Q2KAC0_9ENTR/1-93  AC A0A5Q2KAC0.1
#=GS A0A097R868_HAFAL/1-93  AC A0A097R868.1
#=GS A0A078LL44_CITKO/1-93  AC A0A078LL44.1
#=GS E0SNE9_DICD3/1-92      AC E0SNE9.1
#=GS A0A3N1J408_9ENTR/1-93  AC A0A3N1J408.1
#=GS A0A8I0CVC0_9PSED/1-93  AC A0A8I0CVC0.1
#=GS A0A089Q725_9ENTR/1-93  AC A0A089Q725.1
#=GS A0A5J5FVL7_9GAMM/1-93  AC A0A5J5FVL7.1
#=GS L0LYL3_ENTBF/1-93      AC L0LYL3.1
#=GS W1EHT6_KLEPN/1-93      AC W1EHT6.1
A8APN5_CITK8/1-93                 .MDNHFGKGLMAGLNATCADS.ARNVAGFCSDYKR.GFVLGFSHRMFEKTGDRQLSAWEAGILTRRYGLDKDMVMDFFRENQSN..TTIRFFMAGYR-l.........
A0A378DKK5_KLEPR/1-93             .MENHFGKGLMAGLQASYADT.AAHAANFCADYKR.GFVLGYSHRMFEKTGDRQLSAWEAGILTRRYGLDRDMVMDFFKEGGSG..MAMRYFLAGYR-l.........
Q7CPS7_SALTY/1-93                 .MNNHFGKGLMAGLHAPYAYS.AHHAVNFCSEYKR.GFVLGFTHRMFEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFKENHSG..MAVRFFMAGYR-l.........
YGHW_ECO57/1-93                   .MNNHFGKGLMAGLKATHADS.AVNVTKFCADYKR.GFVLGYSHRMYEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSC..STLRFFMAGYR-l.........
W1HZS7_KLEPN/1-93                 .MENHFGKGLMAGLQASYADT.AAHAANFCADYKR.GFVLGYSHRMFEKTGDRQLSAWEAGILTRRYGLDRDMVMDFFKEGGSG..MAMRYFLAGYR-l.........
A0A0J5LSP4_PLUGE/1-93             .MHNHFGKGLLAGLNTASPHP.CGEQARFCNEYTR.GFVLGYCYRLWKQTGEKSVGALEAGRLTRQYQLDRDIMVEFFTEFKSD..RAVHYFNLGY--gs........
W1DFY9_KLEPN/1-93                 .MENHFGKGLMAGLQASYADT.AAHAANFCADYKR.GFVLGYSHRMFEKTGDRQLSAWEAGILTRRYGLDRDMVMDFFKEGGSG..MAMRYFLAGYR-l.........
A0A2X3EA02_KLUCR/1-93             .MDNHFGKGLIAGMKAPYADS.AQKVVGFCADYKR.GFVLGFSHRMFEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFKEHDSS..TTVRYFMAGYR-l.........
YGHW_ECOLI/1-93                   .MNNHFGKGLMAGLKATHADS.AVNVTKFCADYKR.GFVLGYSHRMYEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSC..STLRFFMAGYR-l.........
A0A5R9LD45_9ENTR/1-93             .MENHFGKGLMAGLQASHADS.ARYAENFCSDYKR.GFVLGYSHRMFEKTGDRQLSAWEAGVLTRRYGLDKDMVMDFFREGSSC..TAVRYFMAGYQ-y.........
A0A2I8PZY5_9ENTR/1-93             .MENHFGKGLMAGLKATQADE.ASRVAHFCSDYKR.GFVLGFSHRMFEKTGDRQLSAWEAGVLTRRYGLDKEMIMDFFRESHSS..TVIRFFMAGYR-g.........
A0A4P7J9L8_9ENTR/1-93             .MDNHFGKGLMAGLNASSADS.ARTVANFCADYKR.GFVLGFSHRMFERTGDRQLSAWEAGILTRRYGLDKEMVMDFFKENQSS..TTIRFFMAGYR-l.........
Q32C64_SHIDS/1-93                 .MNNHFGKGLMAGLKATHADS.AVNVTKFCADYKR.GFVLGYSHRMYEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSC..STLRFFMAGYR-l.........
A0A4Z0N4Q1_SALET/1-93             .MNNHFGKGLMAGLHAPYAYS.AHHAVNFCSEYKR.GFVLGFTHRMFEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFKENHSG..MAVRFFMAGYR-l.........
A0A447LYE8_SALBN/1-93             .MNNHFGKGLMAGLNAPYAYS.AHNVVNFCSDYKR.GFVLGFTHRMFERTGDRQLSAWEAGILTRRYGLDKEMVMDFFKENHSG..MAVRFFMAGYR-l.........
A0A2C6DNP5_9GAMM/1-93             .MNKSFSDGLMAGLVAHEPVI.TKTMLSYSIDYRK.GFVCGFSYALEKLCSDSTMAQYQAGQLAYFYQLEQELLSDFFTDFSGN..HLSDDFTKGYN-s.........
A0A6M8UPF9_9GAMM/1-93             .MQNHFGKGLMAGLRADNAKP.AEALSKFCSDYKR.GFILGYAHHLAESSGDENQAAFKAGLLCRAYGLSGELMEEFFSDSANT..LPRKFFSVGYNQ..........
A0A663AI27_9ENTR/1-93             .MENHFGKGLMAGLQASYADT.AAHAANFCADYKR.GFVLGYSHRMFEKTGDRQLSAWEAGILTRRYGLDRDMVMDFFKESGSS..TAMRYFMAGYR-l.........
Q6DB41_PECAS/1-93                 .MGNHFERGVLAGLRSANPKS.TNDINPYCYDYRR.GYICGYAHHLAETKGDRQQAAFEAGLLSRRYGLERERVAEFFTEQGNP..YAIRFFYAGYD-a.........
A0A656YJ26_SALNE/1-95             .MNNHFGKGLMAGLHAPYAVSgAHHAVNFCSEYKQwQFVLGFTHRMFEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFKENHSG..MAVRFFMAGYR-l.........
A6TDZ5_KLEP7/1-93                 .MENHFGKGLMAGLQASYADT.AAHAANFCADYKR.GFVLGYSHRMFEKTGDRQLSAWEAGILTRRYGLDRDMVMDFFKEGGSG..MAMRYFLAGYR-l.........
H5V3G8_ATLHE/1-92                 m--NHFGKGLMAGLSASQAAS.AQHAARFCHDYKR.GFVLGYTYRLYENTGDRLLSAWEAGLLTRRYALDKDAVIDFFTETQTS..SSRRFFMAGYR-l.........
A0A248KHB0_9ENTR/1-93             .MDNHFGKGLMAGLQASYADS.AQKVIGFCADYKR.GFVLGFSHRMFERTGDRQLSAWEAGILTRRYGLDKEMVMDFFKEHDSS..TTVRYFMAGYR-l.........
A0A377Z327_KLEPO/1-93             .MENHFGKGLMAGLQASYADT.AAHAANFCADYKR.GFVLGYSHRMFEKTGDRQLSAWEAGILTRRYGLDRDMVMDFFKEGGSG..MAMRYFLAGYR-l.........
A0A0H3GTC7_KLEPH/1-93             .MENHFGKGLMAGLQASYADT.AAHAANFCADYKR.GFVLGYSHRMFEKTGDRQLSAWEAGILTRRYGLDRDMVMDFFKEGGSG..MAMRYFLAGYR-l.........
A0A509C250_9ENTR/1-49             .MNNHFGKGLMAGLNAPYAYS.AHHAVNFCPEYKR.GFVLGL------------------------------------------..------------rtvcskrpai
A9MQK4_SALAR/1-93                 .MNNHFGKGLMAGLNAPYAYS.AHNAVNFCSDYKR.GFVLGFTHRMFEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFKESQSG..MAVRFFMAGYR-l.........
A0A240C7Y9_SERFI/1-93             .MGNHFGKGLLAGLKAQNLKP.AAELSKFCSDYKR.GFVLGYAHRLAESTGDENQAAFEAGRLCRDYGLGGESMGEFFSGGASR..LAEKFFCAGYN-r.........
A0A6B2FLN3_9ENTR/1-95             .MENHFGKGVMAGLKASQAGN.AHSVSRFCLDYRR.GFVVGYAHRLSERTGDYLSAAWEAGVLTRRYNLDSALLIDFFREMESAprSVERCFLAGYQ-n.........
A0A8J7H846_9ENTR/1-93             .MANPFGDGVMDGLKAQTPQP.LSEIQHHGLEYRR.GYICGYAYNLAEAVGDRQKAAFEAGLLSRRYGLERDRIAEFFSEYGNP..QTVVYFYAGYD-t.........
E3G3E8_ENTLS/1-93                 .MENHFGKGLMAGLNAPHADS.AREVAHFCADYKR.GFVLGYSHRMYEKTGDRQLSAWEAGILTRRYGLDREMVMDFFRENPSS..LAVRYFMAGYR-l.........
A0A4P8YD87_9ENTR/1-93             .MKNEFARGVMDGMKSQHPQE.IAAFTDYRADYKR.GFILGYCHQLERRYGEMALAAWKAGILTRRYGLDQALMREFFTDFRSE..RLVRSFNRGYQ-e.........
A0A443I944_9GAMM/1-93             .MHNHFGKGLLAGLAAEAAKP.ATELTKFCPDYKR.GFILGFAHHLAESLGDENQAAFTAGQLCRAYGLNGELMEEFFSDGASR..LPRKFFSVGYKQ..........
A0A509C324_9ENTR/1-51             .--------------------.-------------.---------MFEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFKENHSG..MAVRFFMAGYR-l.........
A0A370QNI3_9GAMM/1-93             .MDNHFGRGLMKGIHSKQPMN.SQRITGYCDDFKR.GYVIGYTHHLMETTHDTELASRVAGCLTRQYGLDKEAMIDIFTEYQRS..SSVSAFVSGYA-i.........
YGHW_SHIFL/1-93                   .MNNHFGKGLMAGLKATHADS.AVNVTKFCADYKR.GFVLGYSHRMYEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSC..STLRFFMAGYR-l.........
A0A0L0AP69_9ENTR/1-93             .MNNHFGKGLMNGYNLAGPCP.AAVPAKFCNDYIR.GMVLGYCYQLEKKTGERKLAALEAGRLTRQYNLDKVIMSEFFSEFRSE..RFLHYFNIGYA-g.........
C5BBK2_EDWI9/2-94                 g-KNHFGDGVMDGVKCYEPCG.AGEMRRRCFDYRR.GYVCGFSYSFARRIDNRYMAACRAGERARLYGLERDAIAGFFLSGEDS..QLQRYYYTGYE-r.........
A0A2X4TLL8_SALER/1-93             .MNNHFGKGLMAGLNAPYAYS.AHNAVNFCSDYKR.GFVLGFTHRMFEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFKESQSG..MAVRFFMAGYR-l.........
A0A5Q2KAC0_9ENTR/1-93             .MDNHFGKGLMAGMRAAQADT.AKNVAHFCSDYKR.GFVLGFSHRMFEKTGDRQLSAWEAGILTRRYGLDRDMVMDFFRDTHSS..VALRYFMAGYR-l.........
A0A097R868_HAFAL/1-93             .MKNHFGEGVMDGVRAYEPKS.ANEMSQHCFDYRR.GFVCGFAHSFGKRVDNRYMAACRAGELARDYGLERDAIADFFHGSEDR..GLQEYYYSGYE-r.........
A0A078LL44_CITKO/1-93             .MDNHFGKGLMAGLNATCADS.ARNVAGFCSDYKR.GFVLGFSHRMFEKTGDRQLSAWEAGILTRRYGLDKDMVMDFFRENQSN..TTIRFFMAGYR-l.........
E0SNE9_DICD3/1-92                 .MKNHFGDGILAGLQASTPQS.MSDIRHYCDDYRR.GYVCGYAHQRASLRG-RQQAAFEAGQLCRRYGLMRDIVAEFFTDVSNP..SLVAWFYAGYNQ..........
A0A3N1J408_9ENTR/1-93             .MRNHFGNGLKAGLKSTDTCM.AFMTGRFCSEYNK.GYVLGYCYQIVKKTGDRKSAAWEAGRLTKRYQLDTASMVEFFSEYKAD..ETIRCFFMGYE-v.........
A0A8I0CVC0_9PSED/1-93             .MNNHFGKGLLAGMRAEQADT.AQNAAHFCSDYKR.GFVLGFSQRMFEQTGDRQLSAWEAGILTRRYGLDRDMVMDFFKENPSS..TTLRYFMAGYR-l.........
A0A089Q725_9ENTR/1-93             .MDNHFGKGLMAGMKARQADS.AVNVERFCSDYKR.GFVLGFAHHMAEQTGDRQRAAWEAGVLTRRYQLDKESVADFLKEVNAD..VAVRCFFAGYE-k.........
A0A5J5FVL7_9GAMM/1-93             .MNNHFGNGIQAGLQAQQPIS.PHEISQYCPDYRR.GYVCGYAWQLAESRNDRQQAAFEAGILSRRYGLDRDRVAEFFTEYGNP..HTVHFFYAGYD-s.........
L0LYL3_ENTBF/1-93                 .MDNHFGKGLMAGLKAPYADS.AQKVLGFCSDYKR.GFVLGFSHRMFEKTGDRQLSAWEAGVLTRRYGLDKEMVMDFFKEHESS..TTVRYFMAGYR-l.........
W1EHT6_KLEPN/1-93                 .MENHFGKGLMAGLQASYADT.AAHAANFCADYKR.GFVLGYSHRMFEKTGDRQLSAWEAGILTRRYGLDRDMVMDFFKEGGSG..MAMRYFLAGYR-l.........
#=GC seq_cons                     .MpNHFGKGLMAGLpAstAco.AtpsspFCuDYKR.GFVLGaoHRMaE+TGDRQLSAWEAGlLTRRYGLD+-MVMDFF+EspSs..hslRaFhAGYR.l.........
//