#=GF ID   DUF3821
#=GF AC   PF12863.11
#=GF DE   Domain of unknown function (DUF3821)
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   manual
#=GF GA   23.00 23.00;
#=GF TC   23.00 23.60;
#=GF NC   22.90 22.90;
#=GF BM   hmmbuild  --aminoHMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR024277;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is a domain largely confined to sequences from
#=GF CC   Methanomicrobiales found on putative lipases. The function is
#=GF CC   not known.
#=GF SQ   52
#=GS Q2FMC3_METHJ/66-280       AC Q2FMC3.1
#=GS B8GKG2_METPE/53-244       AC B8GKG2.1
#=GS A0A2V2MPJ9_9EURY/31-246   AC A0A2V2MPJ9.1
#=GS A7I5M9_METB6/37-279       AC A7I5M9.1
#=GS E1RGF9_METP4/35-258       AC E1RGF9.1
#=GS A0A0X8XZ08_9EURY/39-236   AC A0A0X8XZ08.1
#=GS A0A498GZV4_9EURY/15-96    AC A0A498GZV4.1
#=GS Q2FSA4_METHJ/30-219       AC Q2FSA4.1
#=GS A0A110BK48_9EURY/265-472  AC A0A110BK48.1
#=GS A0A498H432_9EURY/49-248   AC A0A498H432.1
#=GS A0A2V2MZW6_9EURY/31-252   AC A0A2V2MZW6.1
#=GS Q2FPL5_METHJ/43-275       AC Q2FPL5.1
#=GS A0A0X3BR79_9EURY/82-284   AC A0A0X3BR79.1
#=GS A0A2V2MRG5_9EURY/30-220   AC A0A2V2MRG5.1
#=GS A0A8J8B5Q2_9EURY/31-231   AC A0A8J8B5Q2.1
#=GS A0A2V2N4H6_9EURY/31-246   AC A0A2V2N4H6.1
#=GS A0A8J8B4C4_9EURY/36-228   AC A0A8J8B4C4.1
#=GS L0HG11_METFS/37-295       AC L0HG11.1
#=GS I7KD82_METBM/31-205       AC I7KD82.1
#=GS I7L0V1_METBM/36-229       AC I7L0V1.1
#=GS H1YY54_9EURY/51-253       AC H1YY54.1
#=GS A0A8J7RZP0_9EURY/41-240   AC A0A8J7RZP0.1
#=GS A0A2V2NBH1_9EURY/28-237   AC A0A2V2NBH1.1
#=GS A0A483CYG9_9EURY/49-247   AC A0A483CYG9.1
#=GS B8GKN6_METPE/272-466      AC B8GKN6.1
#=GS A0A0X3BMX0_9EURY/30-223   AC A0A0X3BMX0.1
#=GS H1YYH2_9EURY/34-236       AC H1YYH2.1
#=GS Q2FS26_METHJ/31-246       AC Q2FS26.1
#=GS A0A2V2N9J2_9EURY/145-364  AC A0A2V2N9J2.1
#=GS Q2FML3_METHJ/25-276       AC Q2FML3.1
#=GS L0HGE7_METFS/29-248       AC L0HGE7.1
#=GS I7LL05_METBM/39-236       AC I7LL05.1
#=GS L0HK99_METFS/34-231       AC L0HK99.1
#=GS B8GEJ2_METPE/100-296      AC B8GEJ2.1
#=GS Q2FTP6_METHJ/20-223       AC Q2FTP6.1
#=GS Q2FPM0_METHJ/138-357      AC Q2FPM0.1
#=GS A0A2V2N5F0_9EURY/42-268   AC A0A2V2N5F0.1
#=GS A7I8Y1_METB6/30-243       AC A7I8Y1.1
#=GS A0A2V2N7S0_9EURY/28-217   AC A0A2V2N7S0.1
#=GS H1YXS6_9EURY/54-258       AC H1YXS6.1
#=GS Q2FLC0_METHJ/30-218       AC Q2FLC0.1
#=GS Q2FTS3_METHJ/31-246       AC Q2FTS3.1
#=GS H1Z310_9EURY/31-241       AC H1Z310.1
#=GS Q2FPL6_METHJ/44-279       AC Q2FPL6.1
#=GS Q2FM49_METHJ/31-253       AC Q2FM49.1
#=GS A7I662_METB6/34-230       AC A7I662.1
#=GS A0A483CUJ8_9EURY/32-220   AC A0A483CUJ8.1
#=GS E1RG97_METP4/25-235       AC E1RG97.1
#=GS B8GGT7_METPE/339-533      AC B8GGT7.1
#=GS A7I8K7_METB6/37-269       AC A7I8K7.1
#=GS A0A498GYF9_9EURY/32-216   AC A0A498GYF9.1
#=GS A0A498H287_9EURY/33-162   AC A0A498H287.1
Q2FMC3_METHJ/66-280                  ..QGDIVFIGEGSLDVTSALN.....................TAGYIAWWQSG-.NL...............................NPAAP.DAVIPVPD.......PYNFRLDPADFVQKT....GDWYQWVDNQK......G........DLAFRVADPSLYL.EIW..DAS...TN...TDVT..GKTIPMGNLGTFCI..DS.NLYSI...MNRTGYLP........G.DSS..IKITVT........SPSGDSLT.YLVGL.NGAEHP...........LTHLQ.VDLprwywi............gqgtdhSVP..SHE..DGWNTSVSYPNGTRIY.QPGIYTVRAECNVNGMKN..............................................................
B8GKG2_METPE/53-244                  ..QGGVIFIGEQGLNLNGVT-.....................TGSQVAWWGAGR.SP...............................TTDAP.SDLQTISD.......PKNFFVSPTIYGTET....GVWYTYPDK--......-........KPAFTIKDPTLAV.KAI..DVR...TG...REVT..SGLVSRGDQVKFQV..ET.NMYSM...TERTGVNG........V.P--..VTIHVT........GPGGIDYT.SLTDS.NGKVHS...........LDPVT.VSS........................---..---..SLYETDPVWNTGNAQY.PEGSYVIWAECNANNMKN..............................................................
A0A2V2MPJ9_9EURY/31-246              ..QGGDIFLGEKNLDVSAATG.....................GAKQIAWWQPGS.NS...............................DTEQP.ADIQTVSD.......NKAFYVSPDIFVGKT....GIWYQWNGTVK......G........SPAFNVKEPSLSL.KIW..DAT...AG...EDIT..GKAIPVGNYANFAV..ET.NMQSL...ATRPGYQA........A.DGP..FKLKVK........TSDGGVYQ.QLVGN.NGKSWP...........LNALT.VNQqlwywv............gegsdhTKF..AKN..DGWNTAAEDQNNNRLY.KAGVYTVWAECNANAMKD..............................................................
A7I5M9_METB6/37-279                  ..PGGSVYIGEQQLNIQPLVNsy................pagGAVSIGWWASAA.SV...............................TSTAP.SQQYNVSSl.....nPSSFYASPSGYGNYL....GNWYAINGSGT......Pn.....ttAAFFTVVDPSLAI.DVW..DIN...TS...TTVS..SGTVIQGDLLTFRI..NT.NLQSAidpNYRTSSVT........P.AVG.sVDIQVK........PSSGNTYA.SLFVNsTSGSST...........YNTQN.IRFqpvnqslwfwgiagngvpsttatsGAG..AIQ..YAWATGATDSTGNNAY.PAGVYTVTAQSDINGQYD..............................................................
E1RGF9_METP4/35-258                  ..PGQTIFIGESGLNIALALGada..............dgttPISKIAWFSSGT.AV...............................ASEQP.AIVYSVGD.......NSSFYVQNAMFSAYE....GSWYGYNGSIG......S.......aTLAFYVYKPSLAV.SIW..DIG...TDgsaTDVT..GKKVTTGDNVTLRV..DS.NLFSL...FERPSNVS........S.QALngIDINVV........TPSGATLV.KLTNSsATNFTT..........nITGIR.PTSsqy..................yllT-S..SAK..PLNGTATPWQLNISQY.SAGTYEVTAKCNINGMKD..............................................................
A0A0X8XZ08_9EURY/39-236              py--DTIFVYEEGLNLTQLRNa...................tTDNPITALRKYQgDN...............................PEKSL.IKSIPVTD.......DTNFEVQDLLVGGEY....GTYYAFSPKDG......V........TGQVMIRKPEIFL.DVV..LASp.yHN...ERLE..GLSVSENTRIAFKV..VCpDVGAF...YTTDGVYP........A.--T..VDIVVT........HPGGAETT.AI---.-GGMN-...........LAGLN.VSS........................TRF..YTD..DPGRPGPIALSGLR--.EVGTYTVRAK--------wsepa.........................................................
A0A498GZV4_9EURY/15-96               ..SGGTVYVGEENLDLTGLDP.....................MIVQLVHYSDFA.--...............................-AGAV.DNSIDVAT.......PSDFDLLAADVGSVT....GAYYVWNATGP......V........-------------.---..---...--...----..--------------..--.-----...--------........-.---..------........--------.-----.------...........-----.---........................---..---..----------------.------------------kpdiyvdvqvpl..................................................
Q2FSA4_METHJ/30-219                  .k-EGTVFVGENDLDISDCNV....................rAGDEIAFWSSGS.--...............................PEGTP.DSRAKVMD.......TRHFFVDPAFFSGKT....GTWYGLISK--......-........KPVFKVEDPWIQL.DVV..EQG...ID...HE--..PEWIKKGNLVSFKI..SS.NMYLL...QERPGSAG........V.P--..VRINLT........GPNETTFT.TLQSP.TGTYN-...........LEKIF.IYY........................SPF..DTG..AVWET-----KDDDKY.PEGEYTAWATILANDIA-e.............................................................
A0A110BK48_9EURY/265-472             ..PGNTIYVGEENLNFATGFGl..................dpISRMIHFNGPYA.NP...............................---II.DRVISITN.......PADFELTPSAVGSTT....GTYYTFGDTPDvl..apAd......sSGYVIVKFPSTAL.DVV.lNNS...RL...DSVN..GRSISRNTALAFKL..TN.NLNGF...SNLDVAAQ........P.A--..IKIDVT........LPDGRVTN.QFGGV.DLTAIP...........MNGTT.VYMgp....................vnLAG..VEA..GTYTAQAKWPSGTDFY.NKG---------------ydsntvafev....................................................
A0A498H432_9EURY/49-248              py--DTIFVYEEDLDLTALRNq...................tTDNPITALRKYQ.DD..............................nPARSL.VNDIDVPD.......DTDFTLLPIEVGDEY....GVYYAFNPTDG......V........TRQILIREPMVFL.DVVlaNPY...HT...ESVS..GLTISENTPLAFKI..IS.PDVGA...FYHAGTTY........P.A-T..VDLVIT........SPGGAEST.IIGGR.DMSGIN...........LTASQ.VYT........................DDP..GQP..GAFS--------LSQL.EQGTYSVQAR--------wsepqsfa......................................................
A0A2V2MZW6_9EURY/31-252              ..QGGDVFLGEKNLDVTAATG.....................SAKQIAWWQPGS.NS...............................DTEQP.ADIQTVSD.......AKAFYVSPDIFVGKT....GIWYAWNGQATa...nqTa.....kgAPAFNVKEPSLSL.KIW..DAT...AG...EDIT..GKAIPVGNYANFAV..ET.NMQSL...ATRPGYQA........A.DGP..FKLKVK........TSDGGVYQ.QLVGN.NGKSWP...........LNALT.VNQqlwywv............gegsdhTKF..AKN..DGWNTAAEDQNNNRLY.KAGVYTVWAECNANAMKD..............................................................
Q2FPL5_METHJ/43-275                  ..QNHTVYFGEEHLDITNCLG.....................GNGYIVTLDVVR.NV...............................-----.TDHIKIND.......PTDFNMPT---DKEE....NVWYQARDAKTpv.ldpQg.....npVPAFITQEPVLSF.DIW..NLN...TD...MKA-..NASVQRGTLLQFKMttDT.NLDDI...TSRLDYTP........G.QGY..VNIGVRapnetnpkDPTGETLL.KLMTLgKNSGDVei.......kpTINLE.VDPsaawvw...........penlnseTAD..PTGwmTGWRDAGTGVETDYNY.KLGTYDVTAVCNVNNMF-k.............................................................
A0A0X3BR79_9EURY/82-284              ..PGDTVYVGEENLVFGPAFGp...................eSVTKLVHFSDPS.--...............................-SGQI.DRTIRVSP.......--PFELTRSVFGTTT....GTYYAFNQSVN......Eitp..anaAGHIFINIPSVAL.DVV.lNTS...LR...DSVN..GKSVTRGNILDFKV..QN.NLVGF...AGVAGAP-........-.--T..MNIEAT........LPGGGVTT.QFGGL.DLRGIP...........ADGTT.VYRgg....................vnLAD..ALA..GTYTAQAKWPATSDFY.GKG---------------fdsnvvtfev....................................................
A0A2V2MRG5_9EURY/30-220              .h-GGTVYVGEEDLDLSSCDV....................hTGDEIAWWDSGN.--...............................AQGTP.TARSRVTD.......VQHFKVDTDSFKGHT....GQWYALITK--......-........KPVFTVEEPTLEV.DMV..ENG...--...MDTE..PTLIKRGNLVSFKI..ST.NLAGI...SQRSGSSG........A.P--..VTINLT........GPNDTVYH.TITSSqTGDFN-...........LDKVY.VYA........................SPY..DTG..AVWDT-----ADAKKF.PDGDYTISAITNVNKIND..............................................................
A0A8J8B5Q2_9EURY/31-231              ..AGETVFRGEEGIDISAGIP.....................VAGTLAWYAPGS.TP...............................GTDAP.SRTVSVAN.......PLNFYVDP---SMEE....GSWYTMPVAVG......A........NAAILVADPAIDV.QLR..R--...GT...TSVN..DATVIRGDLLNFRI..TS.NLDAF...ANRGAPSA........A.P--..TRIRVT........DPNGNVYT.SLVGDvAGVATTfdl.....tatGGNTD.VNT........................NPF..AVA..-AGAT--VWDTAAAPY.SRGTYTYKVDCNANGMND..............................................................
A0A2V2N4H6_9EURY/31-246              ..QGGDVFIGEKNLDVSAGMG.....................GAKQIAWWQPGS.NS...............................DTEQP.ADIQSVAN.......SNAFYVSPDIYVGKT....GIWYQWNGTVK......G........SPAINVKEPSVSI.KIW..DVT...AN...EDVT..GKAVPVGNYADFAI..ET.NMQSF...STRPGYQA........A.DGP..FKIKVK........TSDGGVYE.QLVGN.NGKTYP...........LTGLT.VSQqlwywv............gegndhSKF..PKN..DGWNTAAEDKNNNRLY.KAGVYTFWAECNANAMKD..............................................................
A0A8J8B4C4_9EURY/36-228              ..AGGTVFIGEEGVDITACGV....................aDGDTLGWFAAGR.SP...............................ATGDP.DTTVVVSD.......ATSFFVSPQIFSDRI....GVWYNLATG--......-........NPAFMVADPFLQI.RVF..DVD...YG..aIDRT..GLWVPMDFELQFRI..TT.NLDAM...AQRPGVTG........A.P--..IEVRVT........GEEGVEYS.ALSNR.AGVSTP...........L-IFA.VDR........................SPF..MTG..GIWYP-------DAGY.SRGVYDFYAFCDANNMKD..............................................................
L0HG11_METFS/37-295                  rt--ATIFIGEQGLNLTHALNqaqsyatsftpgtnpamdnvpLNYTVGWWASAA.TI...............................TSTAP.SAKVDLEN......sYRSFTVDQQSFVGYT....GNWYLLAADKAtp.ltdGt.....npIVVFTVADPRLEI.AVW..DFV...QA...SDVT..GKSVTQGQKLGFSV..KT.NMVFNpadNKRGNVSNaltatneyK.DGY..ITIKVK........DESGATLT.GLANNaSQTLATi.........pLTKQF.INSqpwyw.............pynngsTST..TAL..DYWRTDATDYNNQYAY.PVGTYTVWAESTLNKMKD..............................................................
I7KD82_METBM/31-205                  .n-GTNVFVGEENLNFAAAGSn..................fsTTTQLVHYTGE-.-V...............................GKSST.DKTITVTG.......---GVVSELLKGIPV....GNYYDPANT--......-........LHYVNVQNPESTL.DIM.lNSS...PK...DSVN..GKSITRGTGLDFKF..YS.NVD--...--------........-.---..------........--------.-----.------...........-----.---........................---..---..----------------.------------------fggtgatanveitlpgggvvttydgtpltfgangqtqyipnvvfgqaaeagtytavakwars
I7L0V1_METBM/36-229                  ..PGDTVYVGEENLNFGPAFGp...................ePVTKLVHFSDP-.--...............................PSGQI.DRMIVVSP.......--PFELTRSDFGTTT....GTYYAFNQTADvi..tpEn......aAGHIFINIPSVTL.DVV.lNAS...RM...DSVD..GKSVTRDNVLDFKV..LN.NLVGF...AG---VAG........A.P-T..MNIEVT........LPGGGVTA.QFGGL.DLRSIP...........ADGTT.MHLgg....................idLRD..AAA..GIYTAQAKWPATSDFY.GKG---------------f.............................................................
H1YY54_9EURY/51-253                  ..SGDTVFIGEAGLDISNATAw..................wqPKPTIAWYTAGA.NP...............................ATDAP.SSIITISD.......RTDFYVSPDIFTGKT....GAWYFNPGTAT......V........NVSFYVEEASLSV.SLF..NAN...TK...KDIS..NLKAVTDDNIAIRI..DS.NLEAL...FSRRGGGY........S.G--..INVLVE........TPEGATLN.ALYNG.SWTNS-...........ITSIQ.PAN........................TL-..FWI..PNGNMETIWKLDPDMY.KTGTYKVYAQCNVNGMKD..............................................................
A0A8J7RZP0_9EURY/41-240              ..PGDTVFVYEEGLNLSALRNet................tnnPVTALVRYEDGD.-V...............................EKGE-.QNRISVPD......dSSVSLIDVDIDEDET....GTYYAYSRGDN......Gr......tGDRIMIRYPEVRI.EPVlaAPN...HA...DRIE..GITIPAGTAIAFKV..VG.HYVG-...TEYHAGDE........Y.-AM..VDLVVT........SPSGAEVT.YFKGQ.DLSDIP...........LTASV.IYT........................DD-..---..----PGVSGPIVLDRL.EEGEYKVQARW-------sapqg.........................................................
A0A2V2NBH1_9EURY/28-237              ..PGGDVFLGEEGLDVRAAVP....................aPYDEIAFYPPGS.SP...............................GRDIP.LDIRHLE-.......KSSFSVSPNLYSDRT....GSWYQWDSRQA......Ip......gSIAFNVREPRVSV.RIL..QRL...TM...EDIS..SGTVPRGSDLLFQM..DT.NLGSV...AQRPGYNP........AsDGI..FDLLIS........TPGGGTLT.AVETK.TGSSIS...........LTRIT.PQDsl....................qvFPA..IQT..GGWDTGAV-GSGNYLY.AAGMYTIQPKLAFNRVD-e.............................................................
A0A483CYG9_9EURY/49-247              ..PGDTIFVYEEGLDLSALRNa...................aTGNPVTALQRFT.DD...............................NTAKGlIAEIPVPD.......DTDFDLIDASVGGNT....GLYYAYSQADG......L.......tGNRVYVRYPEVSI.EAVlaSPN...HA...DRIT..GITIPVGTPIALRV..VS.PFVGT...DYIAGTTH........A.S--..VDIVVT........TPGGAELT.SFGGT.N-----...........LANLP.VTS........................PQF..YTD..DPGVG---GPIVLDRL.EEGAYQMQA---------rwrtpqgf......................................................
B8GKN6_METPE/272-466                 ..AGATIYAGEQSLNISATGV....................aAGTTLGWFKPGV.RP...............................SNITP.DDSLVVDN.......PISFTVPA---GTKN....GIWYDMTRM--......-........VPAFTVRDPSVGV.RVI..DLQ...RN...VDIT..GQTINASTPVGFIL..DT.NLESF...TQRGASAQ........-.---..VTIRVQ........NPAGQIYR.GLIDD.HGMVNW...........LNNIS.VTT........................NPF..SVK..GAGSYGSLWNTGDLNY.TAGQYQIWAETNVNNIKE..............................................................
A0A0X3BMX0_9EURY/30-223              .s-GENIFVGEENVILDTAVGg..................faGVNQLVHYTGTV.--...............................GASSI.DKTLSVDA.......AGK--VETLEKGIPT....GSYYGQVPGSA......Vt.....gaSPYVNVYNPELTL.DVVldDAS...RK...DSVN..GKSVTRDTKLAFKV..KS.NVDTY...VAGTYMND........N.---..VSIELT........LPGGGVVT.DFGGQ.PLKYNAd........gsTKFIApIDL........................-SK..AEA..GTYTAVGKWA------.------------------rtsdffgkgy....................................................
H1YYH2_9EURY/34-236                  ..KGNTTFIGESGLNINSVFL....................gTENTLSWYSSGS.KP...............................GTDAP.SSVITVSD.......PTNFYVSPDVFTGKT....GAWFNGTST--......-........EAAFYVQKASLSV.SLF..SMN...SS...KEIT..NKKAITNDDIAIRV..NS.NLDAL...FARGIRTA........T.GIGsgIDFYVE........TPDGATLT.KLFDK.SGGSSN...........LSAVK.PNN........................T--..LYW.lPAGTQTGVWQLLQKDY.KAGTYKIYAECNVNGMKD..............................................................
Q2FS26_METHJ/31-246                  ..AGGEVFLGEKGLDVSAATG.....................GSSQIAWWQPGT.NT...............................ETEQP.ADIQQVTN.......AQSFYVSPDIFVGKT....GNWYQWNGSVK......G........PLAFNIKEPSLNL.KVW..DGS...VN...EDVT..GKAIPVGNYGNFVV..ET.NMQSI...ITRPGYQP........A.DAP..FKIKVK........SADGGVYT.NLVGN.NGKEIS...........LTNLA.VNQqlwywv............spdekhTEP..ASN..DGWNTAAEDKYGNRMY.KAGTYTVWAECNANKMKD..............................................................
A0A2V2N9J2_9EURY/145-364             ..QGGDVFLGEEGLDVSLFLN.....................DGDTIAWFSSTS.DK...............................ALTEP.SATVTVDY.......AKSFFIDPSQFTGKL....GYWWIWSGSKA......K........QVAFIVKDPTVGM.RIW..NQN...ED...QDIAndGSKITAGNMVNFRI..DS.NLYSA..iTQRGANLS........D.SQKgiINIVGS.......sNTTQVTYQ.TLQGTlANVSGQd........isLRKLV.VDKnpw..................fwpKND..KTT..SGWNTGARATDESRLY.PNGEYKFYAEVNLNNIKK..............................................................
Q2FML3_METHJ/25-276                  ..PGDIVFLGENGLDLTDITN.....................IPTQIAWYAPCT.EVdssffredtnndvssndippptgyfssgycdKNREP.DHILDIPE.......PENFFVSPDLFIGHA....GDFFLWDGSQK......G........ELAFKVREPYLAL.KVY..DTT...TK...RIIT..DEPIPRGHIVNFII..NT.NLGAV...FNRNGYTD........D.EAP..INLMIE........GPRNSIFRgEVSGL.DTASLS...........LHNLP.VDEtdgdkkwy........wvgvgtdhSNP..SKT..DGWNTGALFSDCDFVY.NLGEYSVWAESHLNDMMD..............................................................
L0HGE7_METFS/29-248                  .s-GAPVFIGETDLDISSAIR.....................DCKVIAWWADEA.DM...............................-SGPA.TKNITIKRvndvilpVNHFNISPDLFSGYP....GNWYCEDKKPT......-........FVVLNVHEPAISI.RVW..DLD...RN...EDIS..GKAVPVTTNITYRI..DT.NLHQAlsyANRTELTP........A.DGF..MTVTLT........NPVGKDMK.NIYTG.SVGSSS...........TQILI.FDGtpfm................tsptYYG..RNL..EAWNRLSRDTTGGYLY.PTGTYTFTVVQNLGGMKD..............................................................
I7LL05_METBM/39-236                  py--DTIFIYEEGLNLTQLRNa...................tTDNPITALRKYQ.DD..............................nPEKSL.IKSIAVTD.......DTNFEVQDLLVDGDY....GTYYTFSPKDG......V........TGQVMIREPEIFL.DVV..LASp.yHN...ERLE..GLSVSENTRIAFKV..VCpDVGAF...YTTDGVYP........A.--T..VDIVVT........HPGGAETT.AI---.-GGMN-...........LAGLN.VSS........................TRF..YTD..DPGRPGPIALSGLR--.EVGTYTVRAEW-------sepa..........................................................
L0HK99_METFS/34-231                  ..AGNTVFIGEQGLDIRAAMD.....................GDSTLGWWASGA.PI...............................ASASP.DKTISVPN.......PGSFSIYPSDFQTHI....GSWYHLSGPST......P.......nGTAFTVADPYIDI.RIE..DTT...VS...TDVT..NKWVPSDDELRFRI..DT.NFVQM...LQRANVNS........V.P--..VTIKVR........GPDGTLFS.GLTSK.SGQTTS...........LVDYQ.LTT........................SPQ..YTN..AIWGT-----SNRAMY.PPGTYSVWVECNVNSIKD..............................................................
B8GEJ2_METPE/100-296                 ..AGGSVYIGEAGLNLNTLAGi...................qNGQTLGWYQSGS.NI...............................QTNSP.DATLVISD.......ASNVYIAP---GTQT....GVWYNLETK--......-........TAAFTVKDPSVAM.KIF..DAK...TG...KDVT..NKQVVEGTLLNFRI..DS.NLDAF...TQRGVTGA........P.---..VTIKVK........DPSGNVYV.ALYDD.LKQSNG...........LVNIP.VSS........................SSF..FVK..GTGTSGAMWDTNYKDY.KDGDYKIWVESNANGMKD..............................................................
Q2FTP6_METHJ/20-223                  ..PGGEVYLGEEGLDIHYAVP....................yPYTSIAYFPAGS.SP...............................GRDQP.LDIMQV-N.......LGRFSVIPDLFYDRT....GAWYQWDQVRG......Tp......gQVAFIVRNPRISL.KVM..DRN...TM...GDRS..YGTVSRGTPLVIQV..ET.NLAGI...TRRPDYSY........N.DGP..VKIQIK........TPGGGTLA.GVKTP.GGGQYV...........FSSFM.PTGel....................gyAPP..IES..GGWDT------GWSGY.ESGLYHIEPKFAVNRMED..............................................................
Q2FPM0_METHJ/138-357                 ..QGGDVFIGEEGLDVSLFLK.....................SGDTIAWFDPTS.EA...............................YLTEP.VGSIVIDN.......PKQFFIDPAQFMNRT....GRWWIWSGDKS......K........QLAFIVKDPSIAL.RIW..NQN...ED...QDINedGGKIPAGNFVNFRI..ES.NLYSA..iIQRGKGLA........P.EDLgiINMVGS.......sNVTQVTYK.FLRGTlNGVPDSd........iaLRELV.VDAnpw..................fwpDND..KTT..SGWNTGALGTDLNRLY.PNGEYNFYAEVDLNNIR-k.............................................................
A0A2V2N5F0_9EURY/42-268              ..QGHTIFFGEEHVDVSDCMN.....................YNGTVFPYAVAL.NV...............................-VRNV.TDAIKIEN.......PKDFTLPT---DKPE....NDWYLSPDGVVpfyaadGs......aVKAFTSQEPSLKF.HIW..NAD...TD...MKV-..ENVTYRGNVARFKYdvET.NLDDI...TTRLDYPN........V.GYY..INMSVI........APDGEQLL.QLMTL.DTRSGIsk......ylpLTGLN.VNPsagwiw...........pdntqpgGSI..GWW..TGWRIADTGQESDYRY.GLGTYSVVALCNVNNMF-k.............................................................
A7I8Y1_METB6/30-243                  ..AGAPVFIGENNVDISAGLN.....................GHSVIAWWPAGA.D-...............................TSGTP.AQTITISG......nPHSYYIDPALFEGYT....GIWYSHDVKPD......-........IPVLNVYQPQINL.SVW..DTD...TN...TDVT..GQSVPLSANVTYRI..DT.NLYLAlnyTYRPNFNP........A.DGF..FTVTLT........SPSGGNMP.SVFTGnVGNSATqi......ipfDSNPM.ITS........................SPYfwQNG..PAWDRNAKSTDGSAVY.QPGTYTFVATANLNGMT-g.............................................................
A0A2V2N7S0_9EURY/28-217              ..PGGTVFIGEENLDISGSGV....................sSGSQIAWWAPGT.SL...............................-DEAP.ADTVTVSN.......PARFSALSATFLGKE....GIWYTLTTK--......-........TPVMKIKQPKLKV.KIK..DTT...SD...FDAT..GKWLPRGHLASFQI..ES.NLYEI...RSRGGISG........A.P--..VDILIT........TPSRSEYS.TVSGP.SGSFR-...........LNGIP.VSS........................SLY..DTG..PVWNTGGT--------.DSGTYTIQAKCTANEL--ds............................................................
H1YXS6_9EURY/54-258                  ..PGETVFIGESGLDITPAMA.....................GNNVIGWYYAGN.NP...............................TTDAP.SSVMTVSN.......PDDFYVIPGVFTGKT....GTWYINPGTPD......A........KIVFYVQKASLSV.SLF..NSE...TG...KEIS..NKIAIENNNIAFRL..NS.NLDAL...FSRNSSGS........T.AG-..VDCYVE........TPDGTTLT.ALIRE.GISGDE...........ITQIT.GIQp.....................kiT-L..FYL..PSGNRETVWTLNPNQY.KAGTYKVYATCNVNSMKD..............................................................
Q2FLC0_METHJ/30-218                  ..PGGTVFLGEEGLDISATGV....................mNGGQIGWWAPGS.S-...............................RSSDP.TELMTVSS.......PDSFYVSPSAFSGKE....GLWYSWPEG--......-........SPVFQVKRPQVSV.RVY..DET...AD...FDAT..GKWIPRGDAVSFRI..SS.NVYEA...NSRGGPDG........Q.---..VDIVLT........SPEGAKYS.SVSGP.SGSFS-...........LSGIP.LTS........................SLT..STG..PVWNTGGV--------.TVGTWTVQAELSMNRIKD..............................................................
Q2FTS3_METHJ/31-246                  ..AGGEVFLGEKGLDVSAATG.....................GSSQIAWWQPGT.NT...............................ETEQP.ADIQQVTN.......AQNFYVSPDIFVGKT....GNWYQWNGSVK......G........PLAFNIKEPSLNL.KIW..DGS...VN...EDVT..GKAIPVGNYGNFVV..ET.NMQSI...ITRPGYQP........A.DAP..FKIKVK........SADGGVYT.NLVGN.NGKEIS...........LTNLA.VNQqlwywv............spdnkhTEP..ASN..DGWNTAAEDKYGNRMY.KAGTYTVWAECNANGMKD..............................................................
H1Z310_9EURY/31-241                  ..QGDTVFLGEEGLTLTPSVFyss...............ggvTDTQLAYFGSGA.NP...............................AASAP.NYVITP-D.......KSSFYVDPNTFGDKS....SAWYSYPNGSK......N.......gHVAFYVNSPSLSV.KLY..AVRp.gDS...FDLT..NGKVVKGEGLDFRI..DS.NLYPI...FTRSGVAA........G.DDG..VDIKFQ........DEVGATLT.ALYDC.TGAVVS...........IVNIH.PTS........................SVF..Y-L..PSGTPACVWDTGNDAY.KMGSYKVWAECNVNGMMD..............................................................
Q2FPL6_METHJ/44-279                  ..QNTTVFIGEEGLDISNALIdpn...............tgnPVYLLGWWGDDV.ES..............................gGHTSA.DKYITIAPg.....sVTNYYVNPTEYMMNNryteGSFYICDETTG......QaiyyngypVVAFYVELPHLEL.VPA..D-D...VC...PDVN.rTGQVFLGTNLNFNI..KT.NLYKI...QNRPGGQN........S.A-I..FDINVI........GPNGKDYN.YLLGPdAGGCNCpdcnpnypaigIKDIN.ILT........................-NK..HQW..QTWDTDAIDPQTGLLYsPQGTYAISATCWANHILD..............................................................
Q2FM49_METHJ/31-253                  ..PGDKVFLGESGLDLTGFID.....................GPVMIAWYHDPC.NYgiiggy...................rgcvppEDETP.TIIKKIED.......PADFFVKPIDFVWFP....GEWYLWDGEKH......G........DVVFIIEEPSISI.NIW..DST...KQ...RDIT..NKAIPQGNYVDFLI..ET.NMDSV...TKREGYNE........E.DAP..FSIFIK.......lGKDGDIIS.ELPGK.DNAMIS...........LLQLP.VDKnkwywv............gldedhTKA..AKG..DGWNT------GDLSV.LPGEYWVWAESNLNGMID..............................................................
A7I662_METB6/34-230                  ..QGGTVFIGEQGLDITSALG.....................SDSTIGWWASGA.AI...............................ATSSP.DSQMPVTT.......PSNFYISPSAFGQYT....GNWYRINSQGK......P.......dGVAFVVADPSLAV.RII..DTT...VS...IDMT..NKWIPRGDQAAFQI..DT.NLNQL...FTRGSSST........E.G--..IDLYVQ........APSGGVYS.ALLDS.SGVAHP...........LSNLI.VSS........................---..---..PSYQTPWSWDTGNSQY.VTGTYTIWAKCDINGMYD..............................................................
A0A483CUJ8_9EURY/32-220              .n-GDTIFDYESGLDLTAFAA.....................NGNQLAKYTDDD.-P...............................-AKGQ.IFSIPIAN.......AASLDLTAIDLQGNY....GTYFLVQNT--......-........LNKVYIRDPTVVFgAVL..END...IT...SSIA..GKTVTKNTPIAFQF..--.---DA...TEVGTYLT........T.A-T..VKVELK........TPGGGVLT.EIPDR.LGVLQS...........FTNHA.LNAprty...............irnidISQ..LEA..GTYSAQAKWQT-----.------------------pggfsdyat.....................................................
E1RG97_METP4/25-235                  .e-GDSVFLGEQGLVLASDVFyss...............ggvSDDQLAYYGGG-.NP...............................ATGTP.DYVLTPS-.......KNSFYVDPSVFSSRL....GLWYSYPNGSK......N.......sYASISVLQPSLDL.RLW..AYRsggES...FDIT..NGKIVKGEALDFRI..DS.NLYPI...FQRAGVTS........G.DDG..IDVKVR........NQVGATLT.ALINC.NGASVS...........IVNVH.PTT........................QQY..F-L..PSGTLTCVWDTGNSQY.NAGSYTVWAECNVNGMKD..............................................................
B8GGT7_METPE/339-533                 ..AGSTVYAGEIGLNIVSTGV....................qNGYTLGCFNTGV.DP...............................QTGAP.AQMMIVND.......VTDFAVHPSAYP---....GIWYNLNSTPK......-........TPVFTVAVPSLAL.TVM..DVT...AN...RPVQ..GDTVLKGRHISFVL..TS.NLEGF...LTRQTGAQ........-.---..VAIKIE........SPTGSIFT.SVIDT.KGVATQ...........LDPLT.ITS........................NSF..LVS..--GTDGTAWDTGNSLY.EPGEYQIWAETELDYHH-h.............................................................
A7I8K7_METB6/37-269                  ..PGATVFIGEQQLNLNNLTAsdp...............llkSDDAIGWWASAA.SP...............................ATSAP.ARSYRLSNl.....dLGSFYVSPAAFGNWP....GNWYGMKNG-M......Wd.....ggPALFSVQDPRVSL.DIW..DLS...TA...TTVT..GGTVHRGDYLAFRI..ST.NMQSAldpAKRGQSAT........G.AEAgnFDLQVK........GPTGITYT.ELLSGtGSDATS...........LTSQN.ANLplwfwg...........tkdakvpSSS..NAA..ANWSTGAVDQTGQNAY.PSGVYTVTARSRLNGMYD..............................................................
A0A498GYF9_9EURY/32-216              ..SGNTVYVGEEGLDLSGIA-.....................GITRLVHYSDF-.--...............................TAGAA.DNIIDVPV.......ATDFDLTATDAGGIT....GTYYAWNAGGL......Ia......gNPFVVVKVPNVTL.DVV.lNNS...RS...DSVN..GKSVSRDTVLAFEL..QN.NVGGL...YATPAIAT........-.---..MDIEIT........TPGGGKLT.QFGGV.STAAVP...........INASK.IYVgg....................msL--..---..----------------.------------------sgveagtytavakwtnnpatg.........................................
A0A498H287_9EURY/33-162              ..SGDTIYIGEEDLDLTPLFA....................gSPPSPAGMNRLV.--...............................HSGDP.ENIIDVPD.......PGRFDLTPVAVGGVT....GSYAVLPQGGA......P........GRQVAVAEPLRLR.VVS..NGS...PS...ESVN..GMVLTENRTIDLVL..VH.NLSGV...SARID---........-.---..------........--------.-----.------...........-----.---........................---..---..----------------.------------------lvgpegg.......................................................
#=GC seq_cons                        ...GsTVFlGEpuLDlosshs.....................ssspluaassus.ss...............................ssssP.sphlsVss.......sssFhlsPshassps....GsWYshsss.t...............sssFhVpcPplsl.clh..sss...ps...pcls..upslspGshlsFcl..po.Nl.uh...hpRsuhss........s.s....lslplp........sPsGsshs.tlhst.ssss.s...........lssls.lsp........................s....htt..ssassss...tsst.Y.ttGsYplhApsshNthh...............................................................
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