#=GF ID   DUF3856
#=GF AC   PF12968.11
#=GF DE   Domain of Unknown Function (DUF3856)
#=GF AU   Ellrott K;0000-0002-6573-5900
#=GF SE   JCSG structure PDB:2HR2
#=GF GA   27.00 27.00;
#=GF TC   27.00 28.70;
#=GF NC   26.90 26.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Repeat
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0020
#=GF DR   INTERPRO; IPR024552;
#=GF DR   SO; 0001068; polypeptide_repeat;
#=GF CC   TPR-like protein. The 2hr2 structure belongs to the SCOP all
#=GF CC   alpha class, TPR-like superfamily, CT2138-like family. A DALI
#=GF CC   search gives hits with the putative peptidyl-prolyl isomerase
#=GF CC   2fbn (Z=16), the SGTA protein (Z=16), the PLCR protein 2qfc
#=GF CC   (Z=16), a putative FK506-binding protein (PDB:1qz2-A; DALI
#=GF CC   Z-score 15.3; RMSD 2.9; 16% sequence identity within 132
#=GF CC   superimposed residues), and with the tetratricopeptide repeats
#=GF CC   of the protein phosphatase 5 (PDB:2bug; DALI Z-score 15.1; RMSD
#=GF CC   2.5; 19% sequence identity within 117 superimposed residues).
#=GF SQ   12
#=GS F4BWB4_METSG/446-544      AC F4BWB4.1
#=GS B4S3C0_PROA2/2-144        AC B4S3C0.1
#=GS Q8KAL8_CHLTE/2-144        AC Q8KAL8.1
#=GS B3EEA9_CHLL2/2-144        AC B3EEA9.1
#=GS Q3B6N0_CHLL3/2-144        AC Q3B6N0.1
#=GS B4SB40_PELPB/2-144        AC B4SB40.1
#=GS A0A1B1PZA5_9CHLB/2-144    AC A0A1B1PZA5.1
#=GS A1BJC6_CHLPD/2-144        AC A1BJC6.1
#=GS A0A166VBG8_9AGAM/700-841  AC A0A166VBG8.1
#=GS Q0YNZ0_9CHLB/2-144        AC Q0YNZ0.1
#=GS A0A317T865_9CHLB/2-144    AC A0A317T865.1
#=GS A0A533U4B3_CHLSQ/2-144    AC A0A533U4B3.1
F4BWB4_METSG/446-544                 esskayekalnlidndl----------------------.------------------------.--KKNPQDARAWEAKSDALIGLGRQEESLDAIEKALE....I...L.N..LSTER...NPK.DGEAW----WSKANVLYGIGRSDEALQAYEKVIEL--------------nhtpr.......................................
B4S3C0_PROA2/2-144                   .................KPLKEVAMSYMALSEAQKKLEE.GAYGEAAAESSKAMDFSKTMPPGE.TFDHEGFDALCYAVLASARAGLGEYDACLEAAGRALH....Y...F.N..RRGEL...QQD.EGKQWIAVVFSRGVAFHETGVYDEALKNLNMAGEMITERKGELPGKETM............................................
Q8KAL8_CHLTE/2-144                   .................KPLKEVVGAYLALSDAQRQLVA.GEYDEAAANCRRAMEISHTMPPEE.AFDHAGFDAFCHAGLAEALAGLRSFDEALHSADKALH....Y...F.N..RRGEL...NQD.EGKLWISAVYSRALALDGLGRGAEAMPEFKKVVEMIEERKGETPGKERM............................................
B3EEA9_CHLL2/2-144                   .................KPLKEVAMSYMALAEAQKKLQG.GMYADAAAESIKAMEISRTMPPEE.AFDHDGFDGLCYAALAPAQAGLGEYAECLQSAERALR....Y...F.N..RRGEL...QKD.EGTQWIAVVFSRAVAMQETGSPEEAAKGFRIAGEMIAERKGELPGREDM............................................
Q3B6N0_CHLL3/2-144                   .................KPLRSVADAYLALSVGERQLQD.GLHAESAASCRSAMDAARSIPAEE.AFDHAGFDAFVHAVLAGALTGLGDYGTGLESADLALY....Y...F.N..RRGEL...EED.GGKLWIRAVFSRGAALEGLGRRDEAFQSFRMACEMLDERNGGMGGLEA-l...........................................
B4SB40_PELPB/2-144                   .................KPLIQVGHSYLALSQGEQQLRD.AHFEEAAESYKRALEVSRTIPAEE.AFDYNGFDALCHTGLSGAYVKLGRYEEALHSAEIGLR....Y...F.N..RRGEL...HQD.EGKQWIAAVFRRAQALEGIGRKEEALKAFQMAGEMIAERKGEMSDKEEL............................................
A0A1B1PZA5_9CHLB/2-144               .................KPLKQVAQAYLAVREGDGKLQA.GEPEGAARAFRRAMELTRTIPEEE.VFEHDGFDAMCLAGLAEALASLGEYPAALDAADGALR....Y...F.G..RRGEL...HQD.EGKRWIAAVLARGLALARSEQAQDALKAFETAREMISERKGELPGKEDM............................................
A1BJC6_CHLPD/2-144                   .................KPLREVAQAYMSLSDAGMQLQA.GSYRDAAESCRKAMEMSRTISLEE.AFDHEGFDAFCFATLSEAFWRLGRFEESLQSAEKALR....Y...F.N..RRGEL...NQD.EGKLWIAAVFSKAVALQETGSPEDAAGFFRTAGEMIAERKGELPGKEML............................................
A0A166VBG8_9AGAM/700-841             .........kvfngdla----------LSLHSLSAQLSElGRREEALAAIQQAVDLRRALAAER.PMVFNGDLAWSLNNLSPQLSELGRREEALAAIQQALE....L...YrA..LAGER...PKVfNGDLAL-SLHSLSTQLSELGRREEALAAIQQALELYR------------alaaerpkvfn.................................
Q0YNZ0_9CHLB/2-144                   .................KPLQEVAMAYKALSDAERHYLD.GAYEAAAESCRKAMEESGKIPDTE.AFDHSGFEAFCHASLSAATGRLCRFEESLASADRALY....Y...F.N..RRGEL...NQD.DGKLWIKAVFSRAIALEGLGRSGEALGEFRKSGEMLAERKGEMPGRDEL............................................
A0A317T865_9CHLB/2-144               .................KPLKQVAQAYMALSKGERGLQE.GAFEEAVSEYQRAMAVTRTIPQEE.VFDHEGFDALCHAGLASALGKLEQYEESLASADKALH....Y...F.N..RRGEL...HKE.AGKQWIAAVMSRAFALARTGRSGDALKAFHTVSEMIADRKGDWPEKEKL............................................
A0A533U4B3_CHLSQ/2-144               .................KPLREVAQAYVALAEAERQIQQ.EMFREAADNCRKAMEISRTIPSEE.AFDHSGFDAFCHARLSEALGRLGLFGDSLASSDKALY....Y...F.N..RRGEL...NQE.DGKFWIAAVFSRGVALQETGLTAEGTKALGTAREMISERKGELPGRETM............................................
#=GC seq_cons                        .................KPL+pVA.uYhALucupppLpt.Gtac-AAtshp+AM-hoRTlPsEE.sFDHsGFDAhCaAsLusAhutLGca-EuLpSA-+ALc....Y...F.N..RRGEL...ppD.-GKhWIuAVaSRuhALpthGpspEAhpuFcpAsEMIsERKGEhPG+Eph............................................
//