#=GF ID   DUF3865
#=GF AC   PF12981.11
#=GF DE   Domain of Unknown Function with PDB structure (DUF3865)
#=GF AU   Ellrott K;0000-0002-6573-5900
#=GF SE   JCSG structure PDB:3B5P
#=GF GA   31.60 30.90;
#=GF TC   31.70 34.10;
#=GF NC   29.90 29.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0230
#=GF DR   INTERPRO; IPR024477;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Family based of PDB:3B5P encoded by ZP_00108531 from
#=GF CC   nitrogen-fixing cyanobacterium Nostoc punctiforme pcc 73102 is a
#=GF CC   CADD-like protein of unknown function. Superposition between
#=GF CC   protein structures encoded by CT610 from Chlamydia trachomatis
#=GF CC   (PDB code 1rwc), pyrroloquinolinquinone synthase C (PqqC, PDB
#=GF CC   code 1otv) and ZP_00108531 revealed that putative active sites
#=GF CC   in CT610 and ZP_00108531 are identical. ( REF:
#=GF CC   http://www.topsan.org/Proteins/JCSG/3B5P).
#=GF SQ   19
#=GS D3V3F3_XENBS/49-272      AC D3V3F3.1
#=GS B2IZC5_NOSP7/4-227       AC B2IZC5.1
#=GS A0A2D0HGI4_9NOSO/9-232   AC A0A2D0HGI4.1
#=GS A0A1D2IAT6_9ACTN/59-271  AC A0A1D2IAT6.1
#=GS W1J529_9GAMM/65-271      AC W1J529.1
#=GS A0A1H8YNI9_9PSEU/46-271  AC A0A1H8YNI9.1
#=GS A0A2R5FY22_NOSCO/46-258  AC A0A2R5FY22.1
#=GS A0A6N7L0U3_9ACTN/45-270  AC A0A6N7L0U3.1
#=GS A0A0K2DXU1_PISSA/7-222   AC A0A0K2DXU1.1
#=GS A0A0M9ZGD8_9ACTN/58-271  AC A0A0M9ZGD8.1
#=GS K9S830_9CYAN/5-228       AC K9S830.1
#=GS D0I8D3_GRIHO/24-234      AC D0I8D3.1
#=GS L7F2X0_9ACTN/59-271      AC L7F2X0.1
#=GS U2ZSC0_PSEA4/25-258      AC U2ZSC0.1
#=GS Q5ZZF6_LEGPH/60-234      AC Q5ZZF6.1
#=GS A0A1E3G9M6_9GAMM/7-230   AC A0A1E3G9M6.1
#=GS A0A8J7FSF4_9CYAN/7-230   AC A0A8J7FSF4.1
#=GS K4IER7_PSYTT/2-235       AC K4IER7.1
#=GS A0A086MR93_9ACTN/52-271  AC A0A086MR93.1
D3V3F3_XENBS/49-272                 tiiynqikdlinpsnlsqeeaklyigelsvfarynstmllraadnirgfc-------------------------------------------------------------------PEFAQELTRNFLEEGGERG.KLPA.....HYVVFSGA....LIADVNFR...VNGWM...PRTSSTRALISLI.D.IL.TwsH.C.P.STV.LGMYYATEAIAIAETLLLQDIT.N.R..L......G...QitgrgtG....N.S...L......K...KLDFYYRMHLD.....E.T.HsaatdnVAV......ERGHQ......EGIARFIR.D.A.....D.L........FHFQ--------------------qpqivdgflqmltpfvdqwveih..
B2IZC5_NOSP7/4-227                  ..................................................NHLTKQLNQLLAQDYVAFSITENPVVQMLSQASFAQIAYVMQQYSIFPKELVGFTELARRKALGAGWNGVAQELQENIDEEMGSTT.GGIS.....HYTLLADG....LEEGLGVA...VKNTM...PSVATSKLLRTVL.S.LF.D..R.Q.V.DYV.LGATYAIEATSIPELTLIVKLV.E.W..L......H...E......G....A.I...P......K...DLQYFFSKHLD.....E.W.E......IEH......EAGLR......TSVAAYIQ.P.E.....E.F........GEFAAGFRAMIDAMQVWWQELAQE.........................
A0A2D0HGI4_9NOSO/9-232              ..................................................NHLTKQLNQLLAQDYVAFSNTENPVIQILNETSFAQIAYVMQQYSIFPKELVCFTELARQKALAAGWNSVAQELKENIAEEMGSTT.QGIS.....HYTLLAEG....LEEGLGVA...VKNTM...PSIATFKLLKTMQ.S.VF.D..Q.Q.M.PYV.LGATYAIEATSIPELTLIVQLL.D.W..L......L...E......G....T.M...P......K...DLEYFFSKHLD.....E.W.E......IEH......EAGLR......TSLAAYIQ.P.E.....E.F........GEFAAGFRATIDAMEAWWQELAQE.........................
A0A1D2IAT6_9ACTN/59-271             ...................adlnerqarmyieelsvfarynaqylkaaat-------------------------------------------------------------AVEGYCPELAHELRRNHLEEGGERG.KVPA.....HYVLYTNA....LLSDLGLL...VNGHV...PAPETETLVNLHQwM.VG.S..H.M.P.SHV.AGAYYATEAVAIAETEILRDIT.N.R..Y......G...E......L....T.I...GrsgselK...ALHYYYELHLD....dE.H.E......AAQvggmsvEAAHI......EGLARFIK.E.SelfhiD.L........PQALDGWLTIMEGMTHWWAQLAH-r........................
W1J529_9GAMM/65-271                 ................nkneaqlyigeisvfarynstmllraadnvrgfc-------------------------------------------------------------------PELAQELTRNFLEEGGERG.KLPA.....HYVVFSGA....LLADLDFR...VNGWM...PRVSSTRTLISLI.D.IL.TwsH.C.P.STL.LGMYYATEAVAIAETLLLQDIT.N.R..L......G...QitgrgsG....N.L...L......P...KLDFYYRMHLD.....E.T.HsaatnnVAV......ERGHQ......EGIAKFIR.D.A.....D.T........F-----------------------hfqqpqivdgflqmltpfvdqwvei
A0A1H8YNI9_9PSEU/46-271             ....................................dwvyeqiadqvgas------------------------------ELNAAQARMYIEELSVFARYNAQFLKQAAT-AVEGFCPELAHELRRNHLEEGGERG.KVPA.....HFVLYSRA....LLADLGLL...VNGHV...PAAETLTLVALHQ.F.MVgS..H.M.P.SSI.AGSYYATEAVAIAETEILRDITdR.YglLt...iqA...S......G....S.E...L......P...QLDYYYRLHLD.....DdH.E......GTQ......VAGLSveaahiEGLAQFIK.K.SelfhiD.L........PQALDGFLQILEAMADWWAQLI--rr.......................
A0A2R5FY22_NOSCO/46-258             ....................................ytfdiietevspss-------------------------------LSAPALLHYINELGVFARHNSQFLKFAAAHSMDAV-PEMAAEFIRNFLEEGG-NV.EIPA.....HYELYSSA....LLKDLDIN...IIGHY...PIACTSELVQIVD.L.LS.R..S.H.SpSII.CGAFYATEGVAIRETKLLRDIT.N.A..YaairgkT...E......A....N.L...-......P...NLKFYYDLHLD.....HgV.E......QGH......ISGIA......RFICKYERyG.L.....K.L........PQICDGFLQGMQAMTMWWTSL---qsv......................
A0A6N7L0U3_9ACTN/45-270             .................................davyrqiralvdpatlt---------------------------------VAQARMYIAELAVFARHNAQFLRLAADQVVGY-CPALAHELDRNFLEEGGEPG.KVPA.....HYILYTRA....LLADLGLL...VNGHV...PADETAKLVLQHQ.V.LVnS..H.M.T.GLI.AGGYYATEGVAVAETEILRDIT.DrYgeLt...tgT...S......G....A.Q...L......T...NLDYYYRLHLD.....E.GhE......AAQvggmsvEEAHI......EGLARFIR.Q.SdlfhlD.L........PQALEGFLQIFNAMADWWTQLA--yr.......................
A0A0K2DXU1_PISSA/7-222              ......................................kqmsadlmalke------------SEFLAHNFNKNPIAQAHQQFNQKQITFFIQQWALIANRYITNLIQMEKTISPNGWEIVATIIQEIITDELSHHT.QKTT.....HY------....--ETLGIN...FHNIT...ASRATSVLFNNMD.T.AF.C..K.E.V.SYI.VGTLYATEAKAIEELLMLRKII.L.S..L......S...K......G....N.L...S......S...TMHVFLDEPIN.....K.W.K......ITH......LEGLN......SSIYKYLS.P.E.....D.Y........GLFRLGFTDMILGLNAWWMNITTE.........................
A0A0M9ZGD8_9ACTN/58-271             ..................aadlnerqarmyieelsvfarynaqylkaaat-------------------------------------------------------------AVEGYCPELAHELRRNHLEEGGERG.KVPA.....HYVLYTNA....LLSDLGLL...VNGHV...PAPETETLVNLHQ.WmVG.T..H.M.P.SHI.AGAYYATEAVAIAETEILRDIT.N.R..Y......G...E......L....T.I...SrsgselK...ALHYYYDLHLD....dE.H.E......AAQvggmsvEAAHI......EGLARFIK.E.SetfhiD.L........PQALDGWLTITEGMTHWWAQLAH-r........................
K9S830_9CYAN/5-228                  ..................................................NTLISRLNQSMGQACSALDAQRNPMVQIMREVSAEQLIYVLQQYAIFPKALVDLMVLTEQKAQQSGWSRIAAELQDNIAEELGRGT.EGVS.....HYRLLAEG....LEDALGVP...VVAIA...PSPATMQLLAHLN.S.IF.R..K.G.G.AYI.LGASYAIEASSIPELLIVQKMI.R.Y..L......L...Q......K....E.M...P......P...TLDHFFTMHLN.....E.W.E......PEH......EADLR......NAIAHYLQ.P.E.....D.L........PEFEAGFYMVLEVMEIWWKGLAIE.........................
D0I8D3_GRIHO/24-234                 ....vsenmkdftpedyqtfysnmvawleptktrlqvglerlrrendrsl-------------------------------------------------------------------DPVIAAFEHNILDESGEGCvKSDS.....HAVLFNKSchtyFEQVYSAP...LSCYA...PSFETLHLRDASL.L.LF.S..K.D.S.FEM.MGACFAQEVHALPQLQRMYQGH.L.A..L......R...D......K....C.H...Nd....wA...QVSRFYDVHFD.....G.T.E......ARH......AEDLR......QTLFGVVD.T.K....pR.M........TLFKSGFISMICLLTQFWKSLE--vr.......................
L7F2X0_9ACTN/59-271                 .............adlnerqarmyieelsvfarynaqylkaaatsvegfc-------------------------------------------------------------------PELAHELRRNHLEEGGERG.KVPA.....HYVLYTNA....LLSDLGLL...VNGHV...PARETETLVNLHQwM.VG.S..H.M.P.SHI.AGAYYATEAVAIAETEILRDITnR.YgvL......TgqgS......G....S.E...L......K...ALHYYYELHLD....dE.H.E......AAQvgglsvEAAHI......EGLARFIR.E.SelfhiD.L........PQALDGFLTIAEGMTHWWAQLAH-r........................
U2ZSC0_PSEA4/25-258                 ................................................ed--LARELEKLIGDKYGSLSTDTNPAITNLAHWQEDDIRFLVKEYSGFSNDSIHLFH---DALIRLEWDGVKEEVKRNLSEEMGALT.NDVP.....HLELMRRG....YKHELGVE...TEGVE...YSQCTEALLTRMR.R.IF.R..SsN.N.AYL.CGALLALEATATFEFKGVEKIL.R.A..L......K...Y......KidggE.I...A......AgsvTGQYILGHVSDspegeN.P.E......DDH......YAGMR......SAIGSYIS.A.E.....K.N........NDLVRGFVSVCTALNSWWENISIE.........................
Q5ZZF6_LEGPH/60-234                 .......................flmnshiqtkslsdpgvseellanyne--------------------------------------------------------------------------------------.-EKN.....HAQMYRHA....LK-KIGLD...VTNRI...PYVATRQFFMRLE.A.LI.V..I.N.A.SKT.LGVMYATETAAIFEHILFKEIS.A.E..L......C...Q......R....KgLdfeN......S...RIKQFHDLHLD.....G.V.E......QAH......KDELG......KFMDHTLA.E.E.....H.VdpniflqeKEIMDGAYAAIDIMEDWWSGLI--na.......................
A0A1E3G9M6_9GAMM/7-230              ...................................kqisndlmifkknvf---------------LANEFDHNPIAKSHKQFNQDQIAFFIQQWALVANRYITNLVQIEKTISNDGWEIVVTMIQEIIADELGRHT.QGAT.....HYEVLTQG....LNETLSVD...FSHLT...PSKTTETLFKKMD.H.IL.S..K.Q.T.PYI.IGTLYAIEAKAIDELLMFKQLM.L.S..L......S...K......N....N.L...S......K...TMQIFLDGHIN.....E.W.E......ITH......LENLN......NSIYKYLI.P.E.....D.Y........DKFRSGFEDILLALNAWWININQE.........................
A0A8J7FSF4_9CYAN/7-230              .................................................d-RLIESLNCSMLQDYAAVNLQKNPVMLLTAHLTVSQLTFIVQQYSIFPKELIGMIDQARNKALVAGWTAVSEVLSENIAEELGSQT.QNIS.....HADLLAQG....LEMGLNVP...VLNAS...PSEATLVLLKALQ.L.VF.D..Q.P.V.AYS.LGAMYAVEATSIAELQLVKRLI.E.F..L......M...E......G....A.L...P......K...PLHYFFEMHLN.....E.W.E......PAH......EKQLQ......TAIAAYLT.P.N.....D.F........HQFQQGFRAVMTIVDAWWHNLLVE.........................
K4IER7_PSYTT/2-235                  ...............................................kli---SEKLDKKLKNDFISVSRNNNPIFSQISAISFNQKLEVIKQYSLFPKNIISMLVGAAYSLSYHNWDIIVEEILQNVNEEMGGGI.GKITkhnqpHYTVLRRV....VQDSFQEN...INSVK...PSQSTQVFIESVK.K.VL.T..H.E.TpEVV.AGGVYALESSAVPELFLLRELV.L.S..A.....aK...D......K....N.Is.vS......Q...TFLDFFEWHIN.....D.I.E......VEH......RDRLM......NMLSSYIK.T.E.....EqW........ILFEEGFNTVMNTMDCWWTDLNKE.........................
A0A086MR93_9ACTN/52-271             .............iaemvgaadlnerqarmyieelsvfarynaqylkaaa------------------------------------------------------------TAVEGYCPELAHELRRNHLEEGGERG.KVPA.....HYVLYTNA....LLSDLGLL...VNGHV...PAPETETLVNLHQwM.VG.S..H.M.P.SHI.AGAYYATEAVAIAETEILRDIT.N.R..Y......G...E......L....T.I...GrsgselK...ALHYYYELHLD....dE.H.E......AAQvggmsvEAAHI......EGLARFIK.E.SetfhiD.L........PQALDGWLTITEGMTHWWDQLAH-r........................
#=GC seq_cons                       ..............................................th.p.............................................................h..t.hstlApELpcNhhEEhGcps.pssu.....HYsLhspu....L.psLGl....Vsuhh...Pu.sTppLlpthp.h.lh.s..+.t.s.uhl.hGuhYAsEAsAIsEhpll+cIs.p.t..L......s...p......t....s.l...s......p...sLcaaachHLD.....E.h.E......ssp......csuht......pulA+aIp.s.p.....D.h........sphhsGFhshhpuMstWWtpLs...........................
//