#=GF ID   DUF4257
#=GF AC   PF14074.10
#=GF DE   Protein of unknown function (DUF4257)
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Jackhmmer:O34881
#=GF GA   27.00 27.00;
#=GF TC   27.50 27.00;
#=GF NC   26.80 24.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR025353;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins is functionally uncharacterised. This
#=GF CC   family of proteins is found in bacteria. Proteins in this family
#=GF CC   are approximately 120 amino acids in length.
#=GF SQ   60
#=GS A0A285CLK3_9BACI/3-82    AC A0A285CLK3.1
#=GS A0A4R2BGL4_9BACI/5-84    AC A0A4R2BGL4.1
#=GS A0A1J6VWL2_9BACI/7-93    AC A0A1J6VWL2.1
#=GS U5L989_9BACI/5-84        AC U5L989.1
#=GS A0A2B2CCT8_9BACI/5-84    AC A0A2B2CCT8.1
#=GS A0A0M0GGH6_SPOGL/5-84    AC A0A0M0GGH6.1
#=GS A0A073KEG8_9BACI/5-84    AC A0A073KEG8.1
#=GS A0A7X2J271_9BACI/5-84    AC A0A7X2J271.1
#=GS A0A248TCJ7_9BACI/5-84    AC A0A248TCJ7.1
#=GS A0A0M0KPJ9_9BACI/5-89    AC A0A0M0KPJ9.1
#=GS A0A0M2SZA2_9BACI/5-84    AC A0A0M2SZA2.1
#=GS I3DZN0_BACMM/5-84        AC I3DZN0.1
#=GS A0A2N0ZD64_9BACI/5-84    AC A0A2N0ZD64.1
#=GS A0A0P6WJ24_9BACI/7-93    AC A0A0P6WJ24.1
#=GS A0A0J5S7C9_9BACI/7-93    AC A0A0J5S7C9.1
#=GS A0A176JAJ0_9BACI/1-70    AC A0A176JAJ0.1
#=GS A0A0M4FRE6_9BACI/5-84    AC A0A0M4FRE6.1
#=GS L5N4L7_9BACI/4-88        AC L5N4L7.1
#=GS A0A398BL12_9BACI/5-84    AC A0A398BL12.1
#=GS A0A6L3V852_9BACI/5-84    AC A0A6L3V852.1
#=GS A0A3L7JU03_9BACI/7-93    AC A0A3L7JU03.1
#=GS A0A5R9F3P9_9BACI/7-93    AC A0A5R9F3P9.1
#=GS A0A841H063_9BACT/48-131  AC A0A841H063.1
#=GS A0A6L8PPE3_BACAN/6-86    AC A0A6L8PPE3.1
#=GS A0A371SK56_9BACI/5-84    AC A0A371SK56.1
#=GS A0A7S8CDQ0_9BACI/6-85    AC A0A7S8CDQ0.1
#=GS A0A7V7RQ71_9BACI/5-84    AC A0A7V7RQ71.1
#=GS Q81EH4_BACCR/6-86        AC Q81EH4.1
#=GS A0A0B0D6I1_9BACI/5-89    AC A0A0B0D6I1.1
#=GS A0A841H1P5_9BACT/17-99   AC A0A841H1P5.1
#=GS A0A2N5GX64_9BACI/5-84    AC A0A2N5GX64.1
#=GS W1SDV8_9BACI/5-84        AC W1SDV8.1
#=GS W4RK25_9BACI/5-84        AC W4RK25.1
#=GS A0A6B3TLG3_9BACI/5-84    AC A0A6B3TLG3.1
#=GS A0A073KA73_9BACI/5-84    AC A0A073KA73.1
#=GS A0A0J1HV58_NIACI/5-84    AC A0A0J1HV58.1
#=GS A0A1S2QY43_9BACI/5-84    AC A0A1S2QY43.1
#=GS A0A5B8Z0L8_BACDA/5-84    AC A0A5B8Z0L8.1
#=GS A0A0Q3QMB3_9BACI/5-84    AC A0A0Q3QMB3.1
#=GS D3G1D2_ALKPO/3-86        AC D3G1D2.1
#=GS A0A3S2X0Z3_9BACI/5-84    AC A0A3S2X0Z3.1
#=GS A0A1G9PED1_9BACI/5-84    AC A0A1G9PED1.1
#=GS A0A2C0ZER1_9BACI/7-91    AC A0A2C0ZER1.1
#=GS A0A370G6H8_9BACI/7-93    AC A0A370G6H8.1
#=GS A0A0A8X4R1_9BACI/5-84    AC A0A0A8X4R1.1
#=GS A0A265NAM2_9BACI/5-84    AC A0A265NAM2.1
#=GS A0A2U0S001_9ARCH/11-92   AC A0A2U0S001.1
#=GS A0A2A8S7A9_9BACI/6-86    AC A0A2A8S7A9.1
#=GS A0A268JDK5_9BACI/5-84    AC A0A268JDK5.1
#=GS A0A3Q9HU69_9FIRM/5-94    AC A0A3Q9HU69.1
#=GS YTVB_BACSU/7-86          AC O34881.1
#=GS Q62RD5_BACLD/5-84        AC Q62RD5.1
#=GS A6CSN2_9BACI/7-93        AC A6CSN2.1
#=GS A0A3Q9QYD8_9BACI/5-84    AC A0A3Q9QYD8.1
#=GS A8FGG1_BACP2/5-84        AC A8FGG1.2
#=GS A0A2N5G8R1_9BACI/5-84    AC A0A2N5G8R1.1
#=GS A0A084H0U8_METID/5-84    AC A0A084H0U8.1
#=GS I0JNM0_HALH3/5-89        AC I0JNM0.1
#=GS A0A3A1QYS8_9BACI/7-93    AC A0A3A1QYS8.1
#=GS A0A6I1F9C0_9BACI/5-84    AC A0A6I1F9C0.1
A0A285CLK3_9BACI/3-82               ....l-LYGFLIG.SFMG.LLTH-AKRNGKIIKPYN.....KK..RVFEYGFLLDCLFGGVAAIAIV.........T.LTEPA.TLDQ....LIFTSVLAG.YGGDTLIA-k..
A0A4R2BGL4_9BACI/5-84               .....ILFAIIIG.GFVG.LAAH-VRKRGKIIKPRK.....TK..KFIYLGFLEEVITGSIASLLLV.........V.TSGTD.STLR....VIFVSIIAG.FGGDALLR-g..
A0A1J6VWL2_9BACI/7-93               ....i-LLPMLMG.GIGG.LGHILIFKNGHFTFPRKfiddqGE..KHYLFGSTKDIIIGVLAGYLSV.........LpVIDTI.PMWY....AIYISLLSG.IGGSSVIT-r..
U5L989_9BACI/5-84                   .....VVFAIFIG.GLVG.AVGH-LKKHGKLIMPKR.....TK..QFIYLGFLEEMVLGSLASALLV.........F.SSDAS.SLLK....VAFLSMLAG.LGGEALIRS...
A0A2B2CCT8_9BACI/5-84               .....IIFSIVIG.GTVG.IVGH-VRKNGKIIMPRK.....TK..RFIYLGFLEELLLGAVAALLLV.........L.YTAPN.STVE....NILFSIIAG.IGGDAVLS-k..
A0A0M0GGH6_SPOGL/5-84               ....i-TFALLIG.GLIG.VVGH-IRKEGKMVKPRR.....TK..KFIYLGVFEEVIMGALAAVFLV.........V.SSDPD.STLK....VVLLAVIAG.FGGDALL--ac.
A0A073KEG8_9BACI/5-84               .....IITAVITG.MFSG.IASHYIANN-KILLPRK.....TR..LAFHPGFLGEMFVGSLASIVGV.........A.MLGAE.TMLD....VIKVSILAG.ISGQTFLLH...
A0A7X2J271_9BACI/5-84               .....LIVAFIIG.GLMG.VLGH-VKQKGRLERPRK.....TK..RYIYLGYWEEFLMGSIASILAV.........L.SSNPE.SSFQ....LVVIAVVAG.YSGEAVLRS...
A0A248TCJ7_9BACI/5-84               .....ILFAALIG.GIVG.VAGH-LQRLGKLVKPRM.....TK..KFIYLGFLEDILLGGLAAVFVI.........V.TTTPD.SPTA....VFIISLVSG.MGGEGILK-l..
A0A0M0KPJ9_9BACI/5-89               .....IIYAAIIG.GITG.FVSHIMRNNKSIIFPRR.....KKnpKSFFLGFLADILAGSTAAVFAVt.......yL.VPETT.SLRT....LMGISILAG.LSAETVLL-n..
A0A0M2SZA2_9BACI/5-84               .....ILFAVIIG.GFVG.MAAH-VRKKGKIVMPRR.....TK..KFIYLGFLEEVLTGSIAALLLV.........V.SSGAG.STLR....VVFVSIIAG.FGGDAILR-g..
I3DZN0_BACMM/5-84                   .....IVFAVLIG.GFVG.MVGH-IRRRGKIIKPRR.....TK..RFIYLGFIEEVVMGALAAVLLI.........V.SSDTD.SIFK....IIFISFVAG.FGGETIVRS...
A0A2N0ZD64_9BACI/5-84               ....i-TFAALIG.GLVG.VAGH-IKRVGKLVKPRV.....TK..KFIYLGFLEDILMGGLASIFLV.........A.TTNPD.SPTA....IFILSLFAG.MGGEAILR-f..
A0A0P6WJ24_9BACI/7-93               ....i-LLPMLMG.GIGG.LGHILVFKNGHFTFPRKfiddqGE..KHYLFGSTKDIIIGVLAGYLSV.........LpVVDTV.PMWY....VIYISLLSG.IGGSSVIT-r..
A0A0J5S7C9_9BACI/7-93               ....i-LLPMLMG.GIGG.LGHILVFKNGHFTFPRKfiddqGE..KHYVFGSVKDIIIGVLAGFISV.........LpVVDTV.PVWY....IIYISLLSG.IGGSSVIT-r..
A0A176JAJ0_9BACI/1-70               .....--------.--MG.IVSH-MKKRGRLEKPRM.....TK..RFIYLGFYEDFAVGTIAAIMLV.........L.SSEPQ.SSFQ....LVLLSIIAG.YSGEAVLKS...
A0A0M4FRE6_9BACI/5-84               .....VLIACMIG.GMMG.ILGH-IKKKGRIEKPRM.....TK..RFIYLGFIEDIIVGMIASALLV.........L.SANPE.SGVQ....LVILSIVAG.YSGEAVLRS...
L5N4L7_9BACI/4-88                   .....LVIAGLVG.GLTG.VIAHLMRNGKVLVYPKKr...aRP..RGIYLGFLADFLIGAAAAVFAVt.......yL.IPEPD.VLRS....LIGVSILAG.MTAENVLL-r..
A0A398BL12_9BACI/5-84               .....IICAFLIG.SIVG.LAGH-VRKRGKIVKPRK.....TK..QYIYLGFLEDVLMAALAAVLLV.........L.AADAD.SALR....VVLLSVTAG.FGGDAVLR-g..
A0A6L3V852_9BACI/5-84               ....i-FFAVLIG.GLVG.VAGH-IKKEGRIIKPRK.....TK..KFIYLGFLEEVILGGLTAACLV.........I.FSAPD.SALK....VIALSIIAG.FGGDSLLR-f..
A0A3L7JU03_9BACI/7-93               ....i-VLPMLMG.GIGG.LGHILVFKDGEFTFPRKfvtenGE..THYVFGSIKDILIGIIAGLLSV.........LpVAESV.PIWY....VVYISLVSG.IGGSSVIT-r..
A0A5R9F3P9_9BACI/7-93               rlivs------IGcGILG.GIANLLNNEESFVMPRIfkdsnGN..SRLLPGFLKELILGAIAGPLLA.........F.PMNETlPWFN....LITMSLIGG.MGGSSILT-a..
A0A841H063_9BACT/48-131             ...laLLVAGVSG.AVGA.FAADLVTDGGRIEQWRR.....DE..AGWSLGFVGKMIVGLVAAIVFL........tL.NPPGN.AWMA....LVGTALAAG.LGGEAILL-a..
A0A6L8PPE3_BACAN/6-86               .....WLTAILVG.GITG.FVSHLINNQGKLLLPRR.....LK..TFFHFGFLTDIFTGSLAALLGL.........V.LFDVT.LIKE....IIKVSIVTA.ISGQTFLLH...
A0A371SK56_9BACI/5-84               .....LLLAIFIG.GSMG.LLGH-AKKQGKIEKPRV.....TK..RFIYLGFLEEMIIGTVAAVLVV.........A.SSDTD.SIFR....VVFLSILAG.YGGERIMQ-r..
A0A7S8CDQ0_9BACI/6-85               .....VLLASGIG.LLMG.MFIH-VRVNGKLKKPRN.....TK..KFFYPGCLEDMFWGAVAGALLV.........I.VSDPA.DWWR....SIFLGIIGG.YSGEQIVR-q..
A0A7V7RQ71_9BACI/5-84               ....m-LLSFCIG.AFVG.VAAH-IQKNGKLIKPRK.....TK..RFIYLGFFEDVIMGALAAVLVV.........L.SANPE.SVIA....VIVTAMIAG.LGGEAILK-g..
Q81EH4_BACCR/6-86                   .....WLTAVLVG.GITG.FVSHLINNQGKLLLPRR.....LK..TFFHFGFLTDIFTGSLAALLGL.........V.LFDVT.AIKE....IIKVSIVTA.ISGQTFLLH...
A0A0B0D6I1_9BACI/5-89               .....LVIAGLIG.GFTG.VLAHLMRNGKVLVFPKVr...kRP..QGIYLGFLADFFIGSAASIFAVt.......yL.IPDPE.VLRT....LIGVSILAG.MTAENVLL-k..
A0A841H1P5_9BACT/17-99              .allg----VIVS.GALGaFAADLVTDAGRIERVRR.....EE..TGWALGFIGKMVVGSVAALVLL........tL.NPPGE.SWLT....LIGTALAAG.VGGEAILL-a..
A0A2N5GX64_9BACI/5-84               .....IIFAIIIG.GFVG.MAGH-VKKRGKIIRPRK.....TK..KFIYLGFLEDVLMSILAAVLLV.........I.SSGAD.TFLR....VLLLSIIAG.FGGEAILK-v..
W1SDV8_9BACI/5-84                   .....IILSFVIG.GSVG.IIGH-VRKYGKIIMPRK.....TK..RFIYLGFLEELLLGAVAALLLV.........L.YAAPN.SLVE....IIIFSIIAG.IGGDAVLN-r..
W4RK25_9BACI/5-84                   .....VIFAMVIG.GFVG.LTAH-VRKRGKIIMPRR.....TK..KFIYLGFLEEILTGSLAAALLV.........V.SSEAD.SLLR....VFLMSIMAG.FGGDALLR-g..
A0A6B3TLG3_9BACI/5-84               .....IIFSVVIG.GTVG.IVGH-VRKHGKLIMPRR.....TK..KFLYLGFLEEWLLGAIAALLLV.........L.YTSPR.SYVE....TIILSFIAG.IAGDATL--sg.
A0A073KA73_9BACI/5-84               .....ILTSVIVG.MISG.FVSHYM-TNKKIVMPRK.....TK..LYFHPGFLGEMFVGSLAAIVGV.........A.ILGPQ.ETLD....VIKVSILAG.ISGQTFLL-q..
A0A0J1HV58_NIACI/5-84               .....IILAGCIG.FGMG.VLTH-AKRYGTIKKPRN.....NK..LTFYPGFLLDGCFGAVGAIVTI.........L.FSDPN.GTER....VILTSILGG.YVGENAI--ik.
A0A1S2QY43_9BACI/5-84               .....IIFSIVIG.GVVG.IIGH-VRKHGKIIMPRK.....TK..KFIYLGYLEEMLLGAIFSLLLV.........M.YISPD.SYVE....KLTISISAG.IGGDVVLTS...
A0A5B8Z0L8_BACDA/5-84               .....IIFAVLIG.GLVG.VAGH-IRNEGKLVMPRK.....TK..KFIYLGFWEEVILGAIGAVFLV.........V.YTDPD.STLK....VIFLSIIAG.FGGDVLLK-f..
A0A0Q3QMB3_9BACI/5-84               .....IIFAVLIG.GLVG.VAGH-LSKEGKLVVPRK.....TK..KFIYLGFWEEVILGALGAVFLV.........V.YTDPD.STLK....VILLSIIAG.FGGEALLK-g..
D3G1D2_ALKPO/3-86                   .....IIYAGLIG.AFLG.LIFHMIRNNKEIKKPKN.....KQ..NSFYLGFIFDMVTGMFGAILMIt.......vI.APIHY.TELD....VFLLRTLVGaIIGEGILTH...
A0A3S2X0Z3_9BACI/5-84               .....LVIAGCIG.GFMG.LLTH-AKRNNTIKKPRN.....HK..TTFNPGVLLDIGFGAVVAVVAI.........L.FADPN.GMER....IFLTAILGG.YAGENAI--nm.
A0A1G9PED1_9BACI/5-84               .....IIFSMVIG.GSVG.IIGH-IRKHGKLIMPRK.....TK..KFIYLGFLEEMLLGSVASILVM.........I.YTTPN.SFVE....TIFLSVLAG.ISGDFILT-r..
A0A2C0ZER1_9BACI/7-91               ....y-VLAIVIG.GVTG.FIFHILFNKGTIMLPVR.....RK..KGFYLGFLADILFGATASTLFV.........S.LFIPE.NMLKdirmVIGYCILAG.LSSQSFLLS...
A0A370G6H8_9BACI/7-93               ....i-VLPMLMG.GIGG.LGHILVFKDGEFTLPRKfvtdeGE..KHYIFGSSKDIIIGIIAGFLSV.........LpVMDTV.PVWY....VIYISLVSG.IGGSSVIT-r..
A0A0A8X4R1_9BACI/5-84               .....VIFAMVIG.GFVG.LTAH-VRKRGKIIMPRR.....TK..KFIYLGFLEEILTGSLAAALLV.........V.SSEAD.SLLR....VFLMSIMAG.FGGDALLR-g..
A0A265NAM2_9BACI/5-84               ...lc--ITIMIG.ILMG.LLTH-TKSNKHIKKPKI.....NK..TSWNPGFLLDCAFGSIAALVGV.........I.VAGPV.EIER....LVLIAILAG.YAGEGLIR-k..
A0A2U0S001_9ARCH/11-92              .....VIVAFLLG.TLGG.FAAELITNKGDIEFPHP.....TK.tNYFDIGFLANIFLGGIAALAYF.........F.VLDTT.DAYK....FVGAMIGAG.VGGSAILT-a..
A0A2A8S7A9_9BACI/6-86               .....WLTALLVG.GITG.FVAHLINHQGKLLLPRR.....LK..TFFHLGFFADIITGSLAALLGL.........V.LFDAT.TTKE....IIKVAIVTA.ISGQTFLLH...
A0A268JDK5_9BACI/5-84               .....IIFSMVIG.GSVG.IISH-VRKHGKIIMPRK.....TK..KFIYLGFLEEILLCLVACLLVV.........I.YTTPN.SLVE....NILVSVLVG.ISSDIILT-k..
A0A3Q9HU69_9FIRM/5-94               ..ilw---IILGG.AFGG.LIKAIFDGEHKLAKPVF.....KG..RYFYLGFLGNIIIGIGTALLGMgyflsmindL.DISRI.STLQ....LLAVSIAFG.IASNLI---ieg
YTVB_BACSU/7-86                     .....VLIACVIG.GIMG.ILGH-VKKRGRLEKPRM.....TK..RFIYLGFLEDWFIGMTASILLV.........L.SADPD.SGIQ....LVILSIISG.YGGEAVLRS...
Q62RD5_BACLD/5-84                   .....VLVACLIG.GIMG.VLGH-VKKRGRLEKPRT.....TK..RFIYLGFFEDILVGMVASILLV.........L.SAEPD.SGIQ....LVVLSIIAG.YGGEAVLRS...
A6CSN2_9BACI/7-93                   ....i-LLPMLMG.GIGG.LGHILVFKGGRFTFPRTfvdedGE..KHYVFGSSKDIIIGVLAGYLSV.........L.PVVETvPVWY....VIYISLLSG.IGGSSVIT-r..
A0A3Q9QYD8_9BACI/5-84               .....IIFSLVIG.GTVG.IIGH-VRKHEKLIMPRK.....TK..KFIYLGFLEEMLLGAVAALLLV.........L.YADPN.SYVE....SIMFSIVAG.IVGDALVT-g..
A8FGG1_BACP2/5-84                   .....VIIACAIG.GVMG.ILGH-VKKKGRLEKPRM.....TK..KFIYLGFIEDWLVGMIAATLLV.........L.SSNPE.SSLH....LVILSIISG.YGGEAVLRS...
A0A2N5G8R1_9BACI/5-84               .....IVFATLFG.GLAG.VIGH-VKSKGKMIMPRK.....TK..KFIYLGFFEDFLTGAMSAALLV.........L.SSGIS.SVLN....VLFISIIAG.LGGEALIR-k..
A0A084H0U8_METID/5-84               .....VIVASLIG.GLMG.LLGH-VKKKGRMEKPRM.....TK..RFIYLGFWEDIAMGTTASILLV.........L.STEPS.SSFQ....LVVLSIIAG.YSGEAVLRS...
I0JNM0_HALH3/5-89                   .....LLIAGLIG.GLTG.VIAHLMRNGKVLVFPKKr...iRP..QGLYLGFLADFLIGAAASIFAVt.......yL.VPDPE.VLRT....LVGISILAG.MTAENVLL-r..
A0A3A1QYS8_9BACI/7-93               ....i-LLPMLMG.GIGG.LGHILVFKGGRFTFPRIlvdedGE..KHYVFGSSKDIIIGVLAGYLSV.........L.PVVETvPVWY....VIYISLLSG.IGGSSVIT-r..
A0A6I1F9C0_9BACI/5-84               .....IILAGCIG.FGMG.VLTH-AKRYGTIKKPRN.....NK..LTFYPGFLLDGCFGAVGAIVTI.........L.FSDPN.GTER....VILTSILGG.YVGENAI--ik.
#=GC seq_cons                       .....llhAhlIG.GhsG.lluH.l++pG+lhhPR+.....sK..+ahYLGFLc-llhGulAAlLhV.........l.sssss.ohhp....llhlSIlAG.huG-ulLp.t..
//