#=GF ID DUF4322
#=GF AC PF14210.10
#=GF DE Domain of unknown function (DUF4322)
#=GF AU Eberhardt R;0000-0001-6152-1369
#=GF SE Jackhmmer:D2PCT9
#=GF GA 27.00 27.00;
#=GF TC 28.10 41.00;
#=GF NC 25.70 21.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF DR INTERPRO; IPR025471;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This presumed domain is functionally uncharacterised. This
#=GF CC domain family is found in archaea, and is approximately 60 amino
#=GF CC acids in length. There is a conserved QTV sequence motif.
#=GF SQ 62
#=GS H2C0X1_9CREN/2-57 AC H2C0X1.1
#=GS H2C4V2_9CREN/2-67 AC H2C4V2.1
#=GS H2C0I4_9CREN/2-67 AC H2C0I4.1
#=GS H2C5D7_9CREN/2-63 AC H2C5D7.1
#=GS H2C0Q3_9CREN/2-67 AC H2C0Q3.1
#=GS H2C558_9CREN/2-67 AC H2C558.1
#=GS Q97XW2_SACS2/2-37 AC Q97XW2.1
#=GS H2C155_9CREN/7-72 AC H2C155.1
#=GS Q97TX1_SACS2/14-72 AC Q97TX1.1
#=GS Q97Y40_SACS2/14-79 AC Q97Y40.1
#=GS H2C738_9CREN/2-67 AC H2C738.1
#=GS H2C1P6_9CREN/7-72 AC H2C1P6.1
#=GS H2C2C3_9CREN/1-35 AC H2C2C3.1
#=GS H2C3K7_9CREN/1-46 AC H2C3K7.1
#=GS Q97WW6_SACS2/1-46 AC Q97WW6.1
#=GS H2C4Y9_9CREN/2-67 AC H2C4Y9.1
#=GS A0A2U9ID93_9CREN/2-67 AC A0A2U9ID93.1
#=GS H2C9Y5_9CREN/2-67 AC H2C9Y5.1
#=GS H2C454_9CREN/7-72 AC H2C454.1
#=GS F9VNH7_SULTO/2-67 AC F9VNH7.1
#=GS H2C1F9_9CREN/2-67 AC H2C1F9.1
#=GS H2C2T7_9CREN/2-67 AC H2C2T7.1
#=GS H2C4A7_9CREN/2-67 AC H2C4A7.1
#=GS Q96Z90_SULTO/2-67 AC Q96Z90.1
#=GS H2C6G7_9CREN/2-67 AC H2C6G7.1
#=GS H2C4L7_9CREN/2-67 AC H2C4L7.1
#=GS Q97VB4_SACS2/1-46 AC Q97VB4.1
#=GS H2C4V7_9CREN/2-67 AC H2C4V7.1
#=GS H2C4K1_9CREN/2-67 AC H2C4K1.1
#=GS Q97TV3_SACS2/26-91 AC Q97TV3.1
#=GS Q97V48_SACS2/2-56 AC Q97V48.1
#=GS H2C770_9CREN/2-67 AC H2C770.1
#=GS H2C197_9CREN/2-67 AC H2C197.1
#=GS H2C778_9CREN/7-72 AC H2C778.1
#=GS H2C0R6_9CREN/2-67 AC H2C0R6.1
#=GS H2C0Z3_9CREN/2-67 AC H2C0Z3.1
#=GS Q97YD0_SACS2/14-79 AC Q97YD0.1
#=GS Q97UV4_SACS2/1-26 AC Q97UV4.1
#=GS H2C5R7_9CREN/2-67 AC H2C5R7.1
#=GS H2C7K6_9CREN/2-67 AC H2C7K6.1
#=GS Q97WP6_SACS2/2-56 AC Q97WP6.1
#=GS Q97U74_SACS2/1-44 AC Q97U74.1
#=GS H2C7S8_9CREN/2-67 AC H2C7S8.1
#=GS Q97XB2_SACS2/14-79 AC Q97XB2.1
#=GS Q97XT0_SACS2/1-46 AC Q97XT0.1
#=GS A0A2U9ICJ0_9CREN/2-67 AC A0A2U9ICJ0.1
#=GS Q97YN1_SACS2/2-67 AC Q97YN1.1
#=GS Q97ZP4_SACS2/2-40 AC Q97ZP4.1
#=GS H2C1Y5_9CREN/2-67 AC H2C1Y5.1
#=GS H2C0X9_9CREN/2-67 AC H2C0X9.1
#=GS H2C529_9CREN/7-72 AC H2C529.1
#=GS H2C2T6_9CREN/2-67 AC H2C2T6.1
#=GS H2C5C6_9CREN/7-72 AC H2C5C6.1
#=GS H2C2E3_9CREN/2-67 AC H2C2E3.1
#=GS A0A2T9WNV6_9CREN/2-67 AC A0A2T9WNV6.1
#=GS Q97WY2_SACS2/2-67 AC Q97WY2.1
#=GS Q97UV5_SACS2/26-57 AC Q97UV5.1
#=GS H2C7U8_9CREN/2-67 AC H2C7U8.1
#=GS Q97YM3_SACS2/1-44 AC Q97YM3.1
#=GS H2C3Z5_9CREN/2-67 AC H2C3Z5.1
#=GS H2C4Y5_9CREN/1-45 AC H2C4Y5.1
#=GS H2C492_9CREN/2-67 AC H2C492.1
H2C0X1_9CREN/2-57 .....ITHHLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVENKSRAYGVS----------..............
H2C4V2_9CREN/2-67 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
H2C0I4_9CREN/2-67 .....IIHHLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
H2C5D7_9CREN/2-63 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRN----..............
H2C0Q3_9CREN/2-67 .....ITHHLPHQNNLQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRTYGVSPQTVRNYVEE..............
H2C558_9CREN/2-67 .....ITHHLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
Q97XW2_SACS2/2-37 .....ITLDLPHQNNTQQIGYKLLSILDFQGKKAENL----------------------------------etlk..........
H2C155_9CREN/7-72 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVENKSRVYDVSPQTVRNYVEE..............
Q97TX1_SACS2/14-72 .....ITPGLPHQNNIQQVGYKLLSMLSFKGRKAEEVSRVLVSACLWNDSVESKSKGYNV-----------rvsg..........
Q97Y40_SACS2/14-79 .....ITPGLPHQNNIQQVGYKLLSMLSFKGRKAEEVSRVLVSACLWNDSVESKSKGYNVSPQTVRNYVEE..............
H2C738_9CREN/2-67 .....IIHHLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
H2C1P6_9CREN/7-72 .....IIHHLPHQNNVQQIGYKLLSMFSFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
H2C2C3_9CREN/1-35 ....m--------------------------------ARTLISACLWNDSVESKSRVYGVSPQTVRNYVEE..............
H2C3K7_9CREN/1-46 .....--------------------MLNFKGKRGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
Q97WW6_SACS2/1-46 .....--------------------MLNFQGEKVEKVAKTLIPACLWNNSVENKSRAYDVSPQTVRNYVEK..............
H2C4Y9_9CREN/2-67 .....IIHHLPHQNNVQQIGYKLLSMFSFKGKRGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
A0A2U9ID93_9CREN/2-67 .....VTPGLPHQNNIQQIGYKLLSMLNFQGEKVDEVAKTLISACLWNDSVENKSRAYDVSPQTVRNYVEK..............
H2C9Y5_9CREN/2-67 .....IIHHLPHQNNVQQIGYKLLSMFSFKGKRGEEVARTLISACLWNDSVESKSRTYGVSPQTVRNYVEE..............
H2C454_9CREN/7-72 .....ITPVLPHQNNVQQMGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
F9VNH7_SULTO/2-67 .....IIPDSIHPKILAQIKEKLFSLINFK---AEEVKKTLITAALSRDSVENKAKEYHH-----------kqrettcknnhieq
H2C1F9_9CREN/2-67 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
H2C2T7_9CREN/2-67 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
H2C4A7_9CREN/2-67 .....VTPVLPHQNNLQQIGYKLLSVLNFKGKKGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
Q96Z90_SULTO/2-67 .....VIPNLPHQNNVQRIGYKLLSMLDFKGKKAEDVGKTLISACLWNSSIENKSSAYNVSPQTVRNYVEE..............
H2C6G7_9CREN/2-67 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
H2C4L7_9CREN/2-67 .....IIHHLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
Q97VB4_SACS2/1-46 .....--------------------MLNFKGKKAEEVARVLVSACLWNDSVEGRSKGYNVSPQTVRNYV--si............
H2C4V7_9CREN/2-67 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
H2C4K1_9CREN/2-67 .....IIHHLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
Q97TV3_SACS2/26-91 .....ITPGLPHQNNLQQVGYKLLSMLSFKGRKAEEVSRVLVSACLWNDSVESKSKGYNVSPQTVRNYVEE..............
Q97V48_SACS2/2-56 pipsl---------NIQQIVYKLLSMINFHGRKGEEATKTLVSTSLHNDSVEKRFQ---------------slqrittn......
H2C770_9CREN/2-67 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
H2C197_9CREN/2-67 .....VIHHLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
H2C778_9CREN/7-72 .....IIHYLPHQNNVQQIGYKLLSMFSFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
H2C0R6_9CREN/2-67 .....VTPVLPHQNNVQQIGYKLLSVLNFKGKKGEEVARTLISACLWNDSVENKSRTYGVSPQTVRNYVEE..............
H2C0Z3_9CREN/2-67 .....IIHYLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
Q97YD0_SACS2/14-79 .....ITPGLPHQNNIQQVGYKLLSMLSFKGRKAEEVSRVLVSACLWNDSVESKSKGYNVSPQTVRNYVEE..............
Q97UV4_SACS2/1-26 .....----------------------------------------MWNDSVESKSKGYNVSPQTVRNYVEE..............
H2C5R7_9CREN/2-67 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
H2C7K6_9CREN/2-67 .....IIHHLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
Q97WP6_SACS2/2-56 pipsl---------NIQQIVYKLLSMINFHGRKGEEATKTSVSASLHNDSVEKRFQ---------------slqrittn......
Q97U74_SACS2/1-44 .....--------------------MIDFKGRKGKEQ--VKPSSQPWNDSIENKSKMFETSSQTVRNYAEK..............
H2C7S8_9CREN/2-67 .....VTPVLPHQNNLQQIGYKLLSVLNFKGKKGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
Q97XB2_SACS2/14-79 .....ITPGLPHQNNLQQVGYKLLSMLSFKGRKAEEVSRVLVFACLWNDSVESKSKGYNVSPQTVRNYVEE..............
Q97XT0_SACS2/1-46 .....--------------------MLNFQGEKVDKVAKTLISACLWNDSVENKSRAYDVSPQTVRNYVEK..............
A0A2U9ICJ0_9CREN/2-67 .....VTPGLPHQNNIQQIGYKLLSMLNFKGEKVDEVAKTLISACLWNDSVENKSRAYDVSPQTVRNYVEK..............
Q97YN1_SACS2/2-67 .....ITLDFPHRNDVEQIGHKLLSMIDFKGSKVEEVAKVLVSAALLNDSIENKLKMFGISDQTVSNYAEK..............
Q97ZP4_SACS2/2-40 .....ITRPLPHQNNLQKIGYKLFSCLT--SREREEVDKTLISA---------------------------yg............
H2C1Y5_9CREN/2-67 .....IIHHLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYDVSPQTVRNYVEE..............
H2C0X9_9CREN/2-67 .....IIHHLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNYSVENKSRAYGVSSQTVRNYVEE..............
H2C529_9CREN/7-72 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNYVEE..............
H2C2T6_9CREN/2-67 .....ITHHLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYDVSPQTVRNYVEE..............
H2C5C6_9CREN/7-72 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVESKSRAYGVSPQTVRNHVEE..............
H2C2E3_9CREN/2-67 .....VTPVLPHQNNLQQIGYKLLSVLNFKGKKGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
A0A2T9WNV6_9CREN/2-67 .....ITPGLPHQNNIQQIGYKLLSMLNFKGKKGEEVAKTLISACLWNDSVENKSRAYDVSPQTVRNYVEK..............
Q97WY2_SACS2/2-67 .....VTPGLPHQNNIQQIGYKLLSMLNFKGKKGEEVARTLISACLWNDSVESKSRAYGVSPQTVTNYVEK..............
Q97UV5_SACS2/26-57 .....ITPGLPHQNNIQQVGYKLLSMLSFKEER--------------------------------------lrry..........
H2C7U8_9CREN/2-67 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
Q97YM3_SACS2/1-44 .....--------------------MIDFKGRKGKEQAKP--SSQPWNDSIENKSKMFKTSSQTVRNYAEK..............
H2C3Z5_9CREN/2-67 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
H2C4Y5_9CREN/1-45 .....---------------------MNFQGEKVEKVAKTLISACLWNNSVENKSRAYDVSPQTVRNYVEK..............
H2C492_9CREN/2-67 .....VTPVLPHQNNVQQIGYKLLSMLNFKGKRGEEVARTLISACLWNDSVENKSRAYGVSPQTVRNYVEE..............
#=GC seq_cons .....lh.hLPHQNNlQQIGYKLLSMLNFKGK+GEEVARTLISACLWNDSVEsKSRAYsVSPQTVRNYVEE..............
//
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