#=GF ID   DUF4447
#=GF AC   PF14590.10
#=GF DE   Domain of unknown function (DUF4447)
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   Jackhmmer:Q8EAP9
#=GF GA   27.20 27.20;
#=GF TC   28.10 28.90;
#=GF NC   24.50 24.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0123
#=GF DR   INTERPRO; IPR027909;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins is found in bacteria. Proteins in this
#=GF CC   family are approximately 170 amino acids in length.
#=GF SQ   20
#=GS A0A096A4J2_9BURK/1-152  AC A0A096A4J2.1
#=GS A0A4Y6IFL0_9GAMM/1-166  AC A0A4Y6IFL0.1
#=GS Q8EAP9_SHEON/1-166      AC Q8EAP9.1
#=GS A0A3A6TKM4_9GAMM/1-166  AC A0A3A6TKM4.1
#=GS A3QH88_SHELP/1-166      AC A3QH88.1
#=GS Q086X3_SHEFN/5-170      AC Q086X3.1
#=GS A0A1S2B102_9GAMM/1-167  AC A0A1S2B102.1
#=GS Q12R96_SHEDO/1-166      AC Q12R96.1
#=GS D4ZBL1_SHEVD/1-166      AC D4ZBL1.1
#=GS A0A4Q5M6E9_9GAMM/1-166  AC A0A4Q5M6E9.1
#=GS A0A411PF04_9GAMM/1-166  AC A0A411PF04.1
#=GS A1S8W3_SHEAM/1-166      AC A1S8W3.1
#=GS A8FZ43_SHESH/1-166      AC A8FZ43.1
#=GS A8H7F9_SHEPA/1-166      AC A8H7F9.1
#=GS A0A3L8Q085_9GAMM/1-165  AC A0A3L8Q085.1
#=GS A0A0N8TXV6_9GAMM/1-166  AC A0A0N8TXV6.1
#=GS A0A4R2F9C6_9GAMM/2-165  AC A0A4R2F9C6.1
#=GS B1KFN6_SHEWM/20-185     AC B1KFN6.1
#=GS A0A094JY89_9GAMM/1-165  AC A0A094JY89.1
#=GS A0A6G9QMX9_9GAMM/1-166  AC A0A6G9QMX9.1
A0A096A4J2_9BURK/1-152             ....-----------MKELIESLGLSTEWLAKHAGLSINEIQQIESGDRKAPQTVIDLLNQIDDNINNVIAQVVEQIgeEERLTGALPEQLDLVRYNNDADLWRYQPEFK-PLPATC-HAALINRLMDKIK-PLGIPIHLVWLRPGEYETWL--N.GREDNSEMRAMWASEQ-e
A0A4Y6IFL0_9GAMM/1-166             ....MAKQPDLNAVEMQYLRMSLGLDAQLLAQLTQTTVEQVLAWEAGTTIAPELVQKKLLEIDETIELRVADTCDGI..ETLFKQEPKRRLAFVVYPTQAVYTQYNPEFLSSLPLTELYTTCAWRIKKECKLILDVEVTLVQLDAEAYKSYRAEH.NLGESPNNRAKWAATQI.
Q8EAP9_SHEON/1-166                 ....MSKNIGLNAIEMSYLRQSLSLSAAQVGQLTNHSEAEVLAWENAETQAPELAQKKLLDIDDIIEMQVLNTTDGI..EALFKKEPKRHLAFVVYPTQAIYTQYNPEFLSSLPLTELYNTAAWRIKKECKLVLEVDVSLINLNVEAYKAYREQN.GLSESRESRAKWAATQL.
A0A3A6TKM4_9GAMM/1-166             ....MSKFAPLNALETQALRLSLGLSQAQIAALTKHSEADVVAWEEGTQALPQQAEKLLLELDDVIEMQVLNTCDGI..EALFKKEPKRRLAFVVYPSQALYQQYNPEFLSSQPLTELYTTAAWRIKKECKLVLEVDVSLVALDAESYKAYRADN.GLSESRESRAKWAADQL.
A3QH88_SHELP/1-166                 ....MAKTAELNAIEIKYLRHSLGLSAAQVGELSKCSEADVLAWEAGEAEVSGLAAKKLLELDETIEMQVLNTCDGI..EELFKKEPKRRLSFVVYPTQAIYTQYNPEFLSSLPLTELYNTAAWRIKKECKLVLEVDVTLVPLDVEAYKAYREKE.GLKESRESRAKWAATQL.
Q086X3_SHEFN/5-170                 ....MSKNTGLNAIEIQCLRQSLGLTTEQVASITKASNEDVMAWESGEQEAPIPAQKKLLEIDDIIEMQVLNTSDGI..EELFKKEPKRRLAFVVYPTQALYTQYNPEFLSTLPLTELYNAAAWRIKKECKLVLEVDVSLVALDAEAYKAYRADN.GMSESRESRAKWAATQL.
A0A1S2B102_9GAMM/1-167             ....MSKQYPLNAIEFQCLRQSLGLGTAQAAELLKVDEAELLSWETGEAQVSELAQKKLLEIDDIIEMQVLNTCDGI..EAMFKKEPKRRLAFVVYPTQAIYTQYNPEFLSSLPLTELYNTAAWRIKKECKLVLEVDISLVPLDVESYKAFREQQgGLGESRESRAKWAAAQL.
Q12R96_SHEDO/1-166                 ....MSKNTGLNAIEIHYLRLSLGLTVEQVAEITKASTDDVLAWETGEQQAPDLAQKKLLDIDDIIEMQVLNTTDGI..EELFKKEPKRRLAFVVYPTQALYTQYNPEFLSSLPLTELYNTAAWRIKKECKLVLEVDVSLVALDAEAYKRYRADN.GMSESRESRAKWAATQL.
D4ZBL1_SHEVD/1-166                 ....MSKNTGLNAIEIKFLRLSLGLTHAQVAELSKASEADVIAWEAGEKPVSGLAEKKLLAIDEIIEMQVLNTCDGI..EELFKQEPKRRLSFVVYPTQAIYAQYNPEFLGSLPLAELYSTSAWRIKKECKLVLEVDVTLVALDVEAYKAYREKE.DLKESREIRAKWAATQI.
A0A4Q5M6E9_9GAMM/1-166             ....MSKFAALNGVEAQALRQSLSLTQQQLAELTQQSIEDVVAWEANEKPMPTQVEKKLLEIDDLIEMQVVNTSDGI..EALFKKEPKRRLAFVVYPTQAIYTQYNPEFVSSLPLTELYNTSAWRIKKECKLVLDVDVTLVPLDVEAYKAYREQN.ELKENRESRAKWAATQL.
A0A411PF04_9GAMM/1-166             ....MSKITPMNAIEMQCLRQSFALSTAQMAELTKVGEAEVISWENGEAEAPMKIQKQLTEIDDTIEMQVLNTTDGI..EALFKTEPKRRLAFVVYPSQAIYTQYNPEFLSSLPLTELYNTAAWRIKKECKIVLDVEVTLIPLDVEAYKAYRADN.NMSESRESRAKWAKTQL.
A1S8W3_SHEAM/1-166                 ....MAKEIGLNGIEMQYLRLSLGLNPAQVGTVTGHSEDDVIAWEAGAAEAPGLAQKKLLDIDEVIEMQLLNTTDGI..EAMFKKEPKRRLAFVVYPTQAVYAQYNPEFLSSLPLTELYNTSAWRIKKECQLVLEVEVTLVPLDVESYKAFREQN.GLGESRESRAKWAAAQL.
A8FZ43_SHESH/1-166                 ....MSKNAGLNAIEIKYLRLSVGLTPAQVAELSKATEEDVLAWEAGEKPVSGLAEKKLLEIDEIIEMQVLNTCDGI..EELFKKEPKRRLSFVVYPTQAIYTQYNPEFLSSLPLTELYNTAAWRIKKECKLVLEVEVTLVPLDVEGYKAYREKE.GFKESRESRAKWAATQL.
A8H7F9_SHEPA/1-166                 ....MSKELGLNAIEMQYLRHSLALTTAQVAEIGKVTEADVIAWEAGEKPAHMPVQKKLLEIDEAIEMQVLNTCDGI..EELFKSEPKRTLSFVVYPTQALYAQYNPEFLGTLPLAELYNTSAYRIKKECKLMLEVDVVLVALEFESYKAFREKE.GLKESRENRAKWAKAQL.
A0A3L8Q085_9GAMM/1-165             ....MAKFAALNAIEVQTLRLSLGLSQQQVADLTKQSLELVQAWETGESAIDAKAEKTLLDIDDVIEMQVFNTCEGI..EELFKKEPKRRLAFVVYPTQAVYTQYNPEFLSSLPLTELYNTAAWRIKQECRL-QEVDVALVALDPEAYKAYRAEN.GLSESRESRAKWAATQL.
A0A0N8TXV6_9GAMM/1-166             ....MAKSNALNAIEMKCLRLSLGLNVEQIAELTKTTADAVTAWEAGEADAPEVAQKKLLEIEDTIEMQVLNTTDGI..EALFKTEPKRRLAFVVYPTQAIYTQYNPEFLSSLPFTELYNTAAWRIKKECQIVLEVEVSLVPLEVEAYKSYRADS.GMSESRESRAKWAATQL.
A0A4R2F9C6_9GAMM/2-165             sayp------LNPIEFCALRWSLGLDEALAAQLLKVSIETLKQWEDGSQPITELAQKQLLDIDDIIEMQVLNTCDGI..EAMFKKEPKRRLAFVVYPSQAIYTQYNPEFLSSLPLTELYTTAAWRIKKECKLVLEVEIALVPLDVDSYKAFREQA.GLGESRESRAKWAASQL.
B1KFN6_SHEWM/20-185                ....MSKNMGLNAIEIKYLRLSLGLTTAQVGELSKASEEDVIAWEAGEKPVSGLAEKKLIEIDETIEMQVLNTCDGI..EELFKKEPKRQLSFVVYPTQALYAQYNPEFLGALPLTELYNTSAWRIKKECKLILEVDVTLVALEVESYKAYREKE.GLKESRESRAKWAATQI.
A0A094JY89_9GAMM/1-165             .mak----YALNPLEFQCLRLSLGLDETKAAEVLKCSVEELQQWELGQQPIPELAEKKLLEIDDTIEMQVLNTCDSI..EAMFKKEPKRRLAFVVYPTQALYTQYNPEFISLLPVTELYNTAAWRIKKECKLVLEVEIGLVPLDVDSYKAFREQA.GLGESRESRAKWAASQL.
A0A6G9QMX9_9GAMM/1-166             ....MSKDTGLNAIEMQCLRLSFGLTTEQVALLTKTTHEAVIAWEAAEAEAPVPAQKKLLEIDDIIEMQVLNTTDGI..EALFKKEPKRRLAFVVYPTQALYTQYNPEFLSSLPLTELYNTAAWRIKKECKLVLEVDVSLIPLDAEAYKAYRADN.GMSESRESRAKWAATQL.
#=GC seq_cons                      ....MSKpsuLNAIEhphLRhSLGLossQlA-LoKsSp--VlAWEuGEptsPtlApKKLLEIDDlIEMQVLNTsDGI..EtLFKKEPKRRLAFVVYPTQAlYTQYNPEFLSSLPLTELYNTAAWRIKKECKLVLEVDVoLVsLDVEuYKAYRtcs.GLuESRESRAKWAATQL.
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