#=GF ID DUF4778
#=GF AC PF16008.9
#=GF DE Domain of unknown function (DUF4778)
#=GF AU Eberhardt R;0000-0001-6152-1369
#=GF SE Jackhmmer:Q8IP16
#=GF GA 27.00 27.00;
#=GF TC 30.40 28.10;
#=GF NC 25.00 23.20;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF DR INTERPRO; IPR031958;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family of proteins is functionally uncharacterised. This
#=GF CC family of proteins is found in eukaryotes. Proteins in this
#=GF CC family are typically between 321 and 791 amino acids in length.
#=GF CC There is a single completely conserved residue P that may be
#=GF CC functionally important.
#=GF SQ 58
#=GS B4I519_DROSE/35-329 AC B4I519.1
#=GS B4G7Q6_DROPE/48-344 AC B4G7Q6.1
#=GS A0A6J2U7J2_DROLE/15-152 AC A0A6J2U7J2.1
#=GS B4JZ74_DROGR/21-309 AC B4JZ74.1
#=GS B4I520_DROSE/45-186 AC B4I520.1
#=GS A0A0Q9WT15_DROWI/40-107 AC A0A0Q9WT15.1
#=GS A0A6P4EIN7_DRORH/93-354 AC A0A6P4EIN7.1
#=GS A0A6P8WA90_DROAB/72-358 AC A0A6P8WA90.1
#=GS Q9V9P9_DROME/70-333 AC Q9V9P9.1
#=GS A0A6I8V4I1_DROPS/57-207 AC A0A6I8V4I1.1
#=GS A0A3B0JV66_DROGU/50-361 AC A0A3B0JV66.1
#=GS B4QER4_DROSI/59-226 AC B4QER4.1
#=GS A8DY55_DROME/59-187 AC A8DY55.2
#=GS A0A6J2U9G6_DROLE/415-520 AC A0A6J2U9G6.1
#=GS A0A0Q9XED3_DROMO/454-599 AC A0A0Q9XED3.1
#=GS A0A0Q9WSN8_DROWI/56-325 AC A0A0Q9WSN8.1
#=GS A0A6I8UKF3_DROPS/34-155 AC A0A6I8UKF3.1
#=GS A0A6J2U9G6_DROLE/70-216 AC A0A6J2U9G6.1
#=GS B4JZ75_DROGR/38-335 AC B4JZ75.1
#=GS A0A0Q9XED3_DROMO/27-336 AC A0A0Q9XED3.1
#=GS A0A6I8UKD3_DROPS/48-346 AC A0A6I8UKD3.1
#=GS B4HR63_DROSE/59-217 AC B4HR63.1
#=GS B3MVP6_DROAN/72-340 AC B3MVP6.2
#=GS B3MKM8_DROAN/46-275 AC B3MKM8.1
#=GS A0A0Q9WVV2_DROWI/633-902 AC A0A0Q9WVV2.1
#=GS B4LSC8_DROVI/93-370 AC B4LSC8.1
#=GS A0A6P4E7U4_DRORH/35-329 AC A0A6P4E7U4.1
#=GS A0A3B0K084_DROGU/34-147 AC A0A3B0K084.1
#=GS B4GBF3_DROPE/2-155 AC B4GBF3.1
#=GS A0A6P4HU72_DROKI/37-347 AC A0A6P4HU72.1
#=GS B3MKM8_DROAN/271-340 AC B3MKM8.1
#=GS B4GKN1_DROPE/70-401 AC B4GKN1.1
#=GS A0A6P4I371_DROKI/59-201 AC A0A6P4I371.1
#=GS B3MKM7_DROAN/45-183 AC B3MKM7.1
#=GS A0A6I8W0G5_DROPS/70-401 AC A0A6I8W0G5.1
#=GS A0A6P4EGF8_DRORH/45-192 AC A0A6P4EGF8.1
#=GS B4N654_DROWI/64-177 AC B4N654.2
#=GS A0A6P4FZC7_DRORH/61-165 AC A0A6P4FZC7.1
#=GS A0A6P4HT12_DROKI/40-178 AC A0A6P4HT12.1
#=GS B4Q4G7_DROSI/70-333 AC B4Q4G7.1
#=GS A0A3B0J6K5_DROGU/52-189 AC A0A3B0J6K5.1
#=GS B4IIH2_DROSE/70-411 AC B4IIH2.1
#=GS B3MHT4_DROAN/67-208 AC B3MHT4.1
#=GS B4Q7D5_DROSI/35-329 AC B4Q7D5.1
#=GS A0A6P4JAR9_DROKI/10-291 AC A0A6P4JAR9.1
#=GS B4Q7D6_DROSI/45-186 AC B4Q7D6.1
#=GS B4K090_DROGR/68-402 AC B4K090.1
#=GS A0A6I8VYS1_DROPS/70-401 AC A0A6I8VYS1.1
#=GS A0A6J2U819_DROLE/59-174 AC A0A6J2U819.1
#=GS A0A484B8B4_DRONA/40-185 AC A0A484B8B4.1
#=GS A0A484BD06_DRONA/85-410 AC A0A484BD06.1
#=GS Q9VJK1_DROME/45-177 AC Q9VJK1.1
#=GS A0A0Q9WA38_DROVI/48-320 AC A0A0Q9WA38.1
#=GS B4JE18_DROGR/68-402 AC B4JE18.1
#=GS A0A6J2TQU1_DROLE/47-172 AC A0A6J2TQU1.1
#=GS A0A0Q9WA38_DROVI/520-672 AC A0A0Q9WA38.1
#=GS Q8IP16_DROME/35-329 AC Q8IP16.1
#=GS B4G7Q7_DROPE/34-156 AC B4G7Q7.1
B4I519_DROSE/35-329 ...............................SQEHCLWRQRNKVEIEQLAKLVGFQPNEIDSFLFNLSLRHYSDLLKPKDCG..WNYCN.VPLC.YPYVCDRYM...A...IFDHRGNLRSPIHERSLKSLLPLLLDY.LNGDspndrkvspiyve.............ypdehqakcrsniEQSDlesmgsLDWIRQ.VFGSPGESK.SEKTRKKTKK...PQP-.-------...VMRSELGNELEp.......esQIDKKKGKNKTFGRQS.VFLNDEL....--AL.AYAKSYDYAEYLMKTLGRHR.F..RDSYIGPVGD------.................................-----.......................................LRTTRTRILIRDLIARKGMNINEKNLRKALKKVDLEWKGTTRADYKREMKT--..........................-AQEISRLYN.....................................................................................................................................................................................................
B4G7Q6_DROPE/48-344 .............................ec--RWHYWSHRNDLAVRQLAKLLEGCPEKVAGFLFDLTLQNYNRLLHPRRCG..YSACH.VPYC.HPYVCERYM...G...IFDDQGNLRDPTHPRSLFQLLKLLQNF.LKGQ.......................................----......TPGCVS.LPFDSSLRE.EERAPVMRHR...SMIEtRCSRWGV...TELSGPSRPMQ..........SKQKGKKSPGQLKRKE.DDEKSEEskgyA---.EIRGSLEISPHYRVPGKDGD.A..VSFYSQDLSDDSRYQLmiddkgrrr...............gmgshsaqlGNLRS.......................................EQALYLKRLIAKMNERRRLERDPQKVLRALSQLDLEDGGPAQDQKTRRNEA--..........................-VAELSKFYT.....................................................................................................................................................................................................
A0A6J2U7J2_DROLE/15-152 ..............................d-SMKRRWFNRNRGVIQQLAKALNKPDDDAFEFLWQLTLSNFSKVLNPKGAG..WNWCR.VPLT.RVDTCDLYG...T...IFDLNGNLRSPIEPASLFKLLELMNYF.LN--.......................................PAKD......RGAKDA.GIFGRKRRK.GSKKG-----...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------klngnsssdrfsgsf......................................................................................................................................................................................
B4JZ74_DROGR/21-309 ..............................l-SSWDLWYARNMKQIKRLASELNKPTREITELIYNLTLQKFNRLLNPRGMR..WNNCR.VPFA.CPAVCDRYV...D...IFDLDGNVRDPANPWNLSKLLKLMQAI.LKLT.......................................----......DVNRIN.EPTNNAIRA.DLCRSKKRDG...GHMK.IERSLKV...ASEQMPNSSAA..........------RRLKASKKEE.DSKEEHVl..dAEIP.TNGSPLNASSRVATPLNATS.H..GAYPMRVFGERAHRLLasdllltdrk............grrhghgspqlDNLRS.......................................EQHRILNEIFRNLSR-----MDPERFLEALTGADLTEEDAKLMKGEKVNVS--..........................-VKDVSAFYT.....................................................................................................................................................................................................
B4I520_DROSE/45-186 ............................vsg---ERRWGQRNGCMIQVLAKMVNKSSSTVCQFLHQLTLQVFARILYPLMLG..WNTLK.VPFV.IPDICELYY...G...IFDECGNLRCSIPTRTLLILISMIQYF.LNLP.......................................KRCG......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------qnntcqgcrsqaddlrnnhspgycgknamtpfsgrei................................................................................................................................................................
A0A0Q9WT15_DROWI/40-107 ..........................rpesv--------------------------EKICQFLYDLTLQKFSRIMNPKMSG..WNIYR.VPLV.QSYTCDLYD...G...IFDRSGNLRRLLSHS------------.----.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------srlg.................................................................................................................................................................................................
A0A6P4EIN7_DRORH/93-354 ..............................r-SAKERWFFTNRRIILSLATALNRPPDLVCDFLHSLTLQNFSRILKPAASS..TISCK.VPYV.NCNVCENYM...S...IFDTRGNVRSRFSQDSLELLMRVVQTV.LKHD.......................................----......------.SLGEAE---.---QFDTSFG...AQRG.AEHRDSM...AKRAGIDRDST..........ARQNGKRRLRNSEARA.QLTKSRF....HSGL.EKPTIGDPGYIFGNNFQPTD.L..DAPVQKPENWAPTDSR.................................TP---.......................................RLSQQLANLLMQVNDKTYLTRDPDQLIAAIRNLEL-DRIVNRPRPPSTDDK--..........................IVKRISDSYY.....................................................................................................................................................................................................
A0A6P8WA90_DROAB/72-358 ...............................KSHKDFWYATNRNIILALGRVLGLHADVVFEFLYTLTLQNFARILNPRGHA..WNLSR.VPFS.QVNICDYYA...G...IFDCNGNVRNPFHPDVLQKLLGMMQQL.LRQD.......................................KS--......------.---RDEVPK.PLPIEK-KAK...P---.-ARSEKI...SQRAGIGPDSL..........ARANGIRRRFQLSERY.QLGGC--....RSQS.LLCGSWD---RYTKHLS---.-..QMWCYKPSQEVVDDIIkaevtvldwgslqgretseeerqvtkalyrllsDNLCT.......................................ARSRELKRLVLSVKQQTGLQNNLEEMLDAMRELNL---KMAVKGEVEYMKR--..........................MTQELSRNYN.....................................................................................................................................................................................................
Q9V9P9_DROME/70-333 ...............................KSHKERWFLTNQRIILALATTLNRPPDLVSDFLHTLTLQNFSEILHPAETEtlSPSCR.VPFV.NCGACENFM...R...IFDTHGNVRSRLSQDSLQLLMSAVQTV.LK--.......................................----......------.----QSPPT.ELRAFDAGVS...GLRG.TLKRDSI...ARRAGIDHDSI..........ARQNGRRRLRNSEARA.SENRSHL....NTGL.EQRTAGDPGYVFGSSLESAG.L..-DVMHTPEKWVFTDSL.................................AL---.......................................ERTRRLAKLLIRVNDKTYLTRDTEKLITAIKDLKLDSNVTNPKKQPPRHSIK-..........................-ANVNSDSYY.....................................................................................................................................................................................................
A0A6I8V4I1_DROPS/57-207 ............................tmp----EKWLELNRRLIATMAEKMHRSTQTIHYMLLRLLHANYAGVLQIVRRR..R-AYK.VPISgYPDALFSNF...S...LFNDLGYISIPMAPEAVGKLMRMMQDY.VSQM.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------qllnrqykwfrngqdkgdlvgllgkqdellkllralfrdsdstfikdmltt..................................................................................................................................................
A0A3B0JV66_DROGU/50-361 .............................dc--RWHYWSHRNDVVIQQLANLLQGCPEKVAGFLYDLTLQNYNRLLHPKRCG..YNACH.VPYC.HPYTCERYK...G...IFDEYGNLRDPTHPKSLFKLLEILQNF.LKGE.......................................----......TSGCVP.LPFDSSLKE.GKQISH---V...GYQV.FRPMAAV...ARCYGMDSKVLk........eALGPGYQRTASSQKPE.DFPSTHQ...aSRKP.KQLQETNGSMRKEEQLEPNG.QhiKEFPMIQRYKVPS-SKe...............................pDNISSdssidlmdekgrrr...........gmgshcnqlgglrfEQAKQLRVLIQALNEKRGLDKNHQKIITALAHVDLEDDKKKAKYEKSRRNE--..........................AFALLSKFY-sttv.................................................................................................................................................................................................
B4QER4_DROSI/59-226 ...........................tlpp-----RWLEVNRRVIFALAKRLCRSPEAAHYILLRLLYANYRKVMMISRK-..RRRYK.VPLS.GFPDQDLFSa.sA...HFDSNGFLSDPMAPETLGKLLHMMQDYiLRL-.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------ralnrkykwcgngedfgdvllllgeqdemvrllrdlfgdsdvvsipkllsalseleinnlygkykkk..................................................................................................................................
A8DY55_DROME/59-187 ...........................tlpp-----RWLDLNRRVIFALAKRLCRSPEAAHYILLRLLYANYRKVMMISRK-..RRRYK.VPLS.GFPDQDLFSa.sA...HFDSNGYLSDPMAPETLGKLLHMMQDY.I---.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------lrlralnrkykwcgngedfgdvllllgeqde......................................................................................................................................................................
A0A6J2U9G6_DROLE/415-520 gvgestsshsggaistataganskgnpneta---------------------------------------------------..-----.----.---------...-...---------------------------.----.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..-------NNDD-----.................................----Tgksgkg...........................gggpgsARAKEMTNIIDNVNKKTGLNKDVDTLVKEIKRVSL---EETRDKKGVHTKD--..........................AVKDISATYN.....................................................................................................................................................................................................
A0A0Q9XED3_DROMO/454-599 ..............................n-SEERRWCLHNGSMLRKLAGIVRKPLHQVCSFMFELTMKKFGEITNPKCSR..WTYCR.VPLV.RPDTCALYD...G...IYDRQGNLRPVFHPYILHLVVAILRHY.LNLP.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------cavekppskrpeyemfisrkgttckdffkprrkrgkrfgrggrgg........................................................................................................................................................
A0A0Q9WSN8_DROWI/56-325 ............................tne---FRFWCRRNSNMIINLSDKLGKSAEDVAVFLYELTLQNYSQIMNPKKSG..WNQCNrVPFT.QPFVCDGFL...S...TFDERGNLRNPMNPRSLKRLLRIFQSL.TTDE.......................................PNDI......THGSIG.KIGSA-FKK.EEQTSVFGYD...EDQR.SISDNKV...RDKFTLPSPLE..........--DDELNQLTNQFK--.PFNRRRA....SAIG.AMENFQDSMIRLMDEKGRRR.G..KG----SNAFQLGAL-.................................---RG.......................................KSAQFLRFLISRVNEQQSLTEEPNDVIKAIDELHLHQSANRRKRGKHRNKR--..........................DVDNIADHYN.....................................................................................................................................................................................................
A0A6I8UKF3_DROPS/34-155 ..............................s-SPQHQWWNRNCVIVRLLANAVDQSAGNVCTFLYQLTLNLFSRILGPLVMG..WNTLK.VPFA.MSDTFDLYY...G...IFDENGDLRRPMAMKTFVLLLIMMKRF.L---.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------clpcrmmrprdktghspimfctkt.............................................................................................................................................................................
A0A6J2U9G6_DROLE/70-216 ..............................a-TTKRIWFNINRIIIISLSRLLDRPQHAVFEFLYTLTLQNFSKALNPRGQT..WNACR.VPLT.NSGVCNMYV...E...IFDCRGNLRNPYHPNALLNLMQVIQAV.LGEE.......................................ERQD......EEAHRI.LYGKPK---.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------dlpeppwkaaidaakeigalrrsrahakqs.......................................................................................................................................................................
B4JZ75_DROGR/38-335 ..............................q-SAERRWCLNNNVMLRRLSSHVQQPLIEVCTFLFQLTLAKFGQILNPRCSQ..WSYYR.VPFV.RPDTCAIYD...G...IFDNRGNLRNPLHPFIEYLVLIILDHY.LSLP.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------cekvegrrntavdtiygrgggackdvfkdalrgqadslrhffnnskfgfgglsgsngdadadahadgsgdgdgkddvdgenkyddgddddhengngrdssnrlynkygdvkdggvkrksekggkgggkgkrrkgskgskgskgdddankrkknikdisnlysdvveerytidlptlyakkkakkrvkvkkrgggdqk
A0A0Q9XED3_DROMO/27-336 ..............................n-KDWEKWQTRNLNVAHHLATKLDKPIDEISDLMYNITVQNYSQILNPISGF..ANKCE.VPFA.SADACTKLL...T...IFDFEGNLRHPSDPKSLFQLLQLMQHI.SRWGsn..................................wekKQSQ......IEKQMQ.HGTESIIPElRLPLSCMKKS...GKSE.IIIL--N...KNRLSLNNNIK..........DNNNYYINNDNMSTKKlSKKRSHI....SVVK.SIDKHNNLKPHSKSIFGVKKaY..KSSKVEVNTSKAKKGAryslfnmqeillm......ddngrrrglgtidlAILKS.......................................KQKYFLRLLL----E-KNMKDNPDQLLNALIEADLGDP---LKETKPDNAA--..........................-AAEISNFY-savvs................................................................................................................................................................................................
A0A6I8UKD3_DROPS/48-346 .............................ec--RWHYWSHRNDLAVRQLAKLLEGCPEKVAGFLFDLTLQNYNRLLHPRRCG..YSACH.VPYC.HPYVCERYM...G...IFDDQGNLRDPTHPRSLFQLLKLLQNF.LKGQ.......................................----......TPGCVP.MPFDSSLRE.EERAPVVRHRsmdPIGT.RCLRWGV...TELSGPSRPMQ..........SKQKGKKSPGQLKRKE.DDEKSEEskgyA---.EIRGSLEISPHYRVPGKDGD.A..VSFYSQDLSDDSRYQLmiddkgrrr...............gmgshsaqlGNLRS.......................................EQALYLKRLIAKMNERRRLERDPQKVLRAMSQLDLEDGGPAQDQKTRRNEA--..........................-VAELSKFYT.....................................................................................................................................................................................................
B4HR63_DROSE/59-217 ...........................tlpp-----RWLEVNRRVIFALAKRLCRSPEAAHYILLRLLYANYRKVMMISRK-..RRRYK.VPLS.GFPDQDLFC...As.aHFDSNGFLSDPMAPETLGKLLHMMQDYiLR--.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------lralnrkykwcgngedfgdvllllgeqdelvrllrdlfgdsdvvsipkllgalselein..........................................................................................................................................
B3MVP6_DROAN/72-340 ..............................t-DPKSRWFDVHKHIILSMAITLNRPPDVVLDFLYNLSMQNFRNILEPFRGY.pAGPCN.VPFA.NGNICTQYM...S...IFDTRGNVRNPFHRNSLAMLIRMMQNV.LS--.......................................----......------.---NKQFRR.HSPIDDFFVQ...PHPL.RDRAAER...AKRAGIDSSSA..........ARQNGRRRLREADFKA.QENRRILy..nEMTD.FLYHKPDVGSRFWEAVEPKT.L..QDFDLNDNEYGISSA-.................................--FST.......................................YQAEELTALIDLLNQRVLLTRHLDDLLEAIKSLKLVDPAVEKTGLSRVSAERI..........................YVKEISKSYN.....................................................................................................................................................................................................
B3MKM8_DROAN/46-275 .............................sg--ARRFWRERNDLVIQRMAKLLDCYPEEIGGFLHELTLQNYSRLLYPVGCG..RSPCN.VPLC.HPTVCDRYM...G...IFDEGGNLRDPTNPRSLFSLLYLLQRC.LNGQplggcsglpinsnkkc.......gfeecyprtgpenyigLDQE......KVWQLY.RFGNPKKRK.RLRDQSMSFV...PSPS.IISTRVT...VPRSSISSTYVsnmrvlksedSMEDSWRSRPGIKTTH.TDPQMDPe..rNFEA.ELINI---------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------qr...................................................................................................................................................................................................
A0A0Q9WVV2_DROWI/633-902 ............................tne---FRFWCRRNSNMIINLSDKLGKSAEDVAVFLYELTLQNYSQIMNPKKSG..WNQCNrVPFT.QPFVCDGFL...S...TFDERGNLKNPMNPRSLKRLLRIFQSL.TTDE.......................................PNDI......RYGSIG.KIGS-AFKK.EEQTSVFGYD...EDQR.SISDNKV...RDKFTLPSPLE..........--DNEVNQLTNQFK--.PFNRRRA....SAIG.AMENFQDSMIRLMDEKGRRR.G..KG----SNAFQLGAL-.................................---RG.......................................KSAQFLRFLISRVNEQQSLTEEPNDVIKAIDELHLHQSANRRKRGKHRNKR--..........................DVDNIADHYN.....................................................................................................................................................................................................
B4LSC8_DROVI/93-370 ...............................SSPRDYWFNANRGIILALSRAVGLHADVVSDFLYTLTMQNFAKVLNPRNSY..CYNCH.VPLC.TFDACDFNC...G...IFDSEGNVRTPYQPESLLKLLSVLQLV.LKGG.......................................KESE......NGAHKC.LFGDAKCPA.RKFGLRPTRC...TQK-.------I...ADRSGIGPNSL..........ARQNGLRRRFTRYERY.YLDGNDP....NAGKpGAGDAALEASTRRKHF----.-..-DNMEGYIGY----CKgsi..........................akatS---Glyage............................kliaysERRDYLRKLLNRIKDRVGIERNLDDLVVALTGFDL-----NKARESEMSRTRG..........................IAQNISKEYN.....................................................................................................................................................................................................
A0A6P4E7U4_DRORH/35-329 ...............................SQEHYLWLQRNKFEILKLAKMVGCHPEEIDGFLFELSLENYSRQLNSNGCG..WDACN.VPLC.YPHICGRYM...S...IFDHRGNLRCPNDSEGLYKLLSLLLDF.LNGDspegqrdsptykvrp........dghpanrhsksvkvlrPDSE......SSDDES.LPPIKWSLT.NTRVPR----...TRES.IHHESQP...VQEQKPDLESQ..........EDLGKKKQNKKFGRQT.VFLNDEL....--AL.AFAKPNDIVEYLMKILGRHR.S..RDSYIGPVGD------.................................-----.......................................LRTKRIRILIRNLVKRKGTHITNHDLRQALYKVDLEWKSTAKADYMREMKT--..........................-AKEISNLYN.....................................................................................................................................................................................................
A0A3B0K084_DROGU/34-147 ..............................q-SPQGQWWKRNCGTIQVLANAVDQSASSVCTFLYQLTLNLFSRILNPLTMG..WNTRK.VPFV.MSNTFELYY...G...IFDENGDLRRPMPARMFLLLLIIMQRF.L---.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------clpcrmirprakcghs.....................................................................................................................................................................................
B4GBF3_DROPE/2-155 .............................pe-----KWLELNRRLIATMAEKMHRSTQTIHYMLLRLLHANYAGVLQIVRRR..R-AYK.VPISgYPDALFSNF...S...LFNDLGYITIPMAPEAVGKLMRMMQDY.VSQM.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------qllnrqykwfrngqdkgdlvgllgkqdellkllralfrdsdstfikdmlktllyld.............................................................................................................................................
A0A6P4HU72_DROKI/37-347 ..............................t-QDRRQWREQNQAVIERLSQMVGAWPQDVGDFLYDLTLKKYSHLLNPRDRG..WSFCK.VPLC.YPNVCDRYM...G...IFDRSGNLRDPTHPKCLHHLLQLLLDH.LNGGcynsclglplhaeysggcppslrryrnvvkihdsevegiDEHA......RESLTW.DPGSPLPRK.FNIKSKAATI...PPP-.IESQNDLptsSPRMSIEGPYKrd......dpDKAKKQIPRKDLGRYS.VFLNDEL....A-LA.HNRSYFYMENMVNEALERRR.N..KNSYVGPIGN------.................................-----.......................................LRTERLRVLIKTLIEKKGRRVDPQELNRIIDKVDL-----SHHVEKKRLKQ--..........................IAIEISTLY-ss...................................................................................................................................................................................................
B3MKM8_DROAN/271-340 ............................ini---------------------------------------------------..-----.----.---------...-...---------------------------.----.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................----Q.......................................RRASQIREIFNDFVEQQIVHVDAVNLMEAIRLVDLGDLESESDEKRKGIGKVSa.......................nkIVDEISKFYN.....................................................................................................................................................................................................
B4GKN1_DROPE/70-401 ..............................l-TDKQRWFLINQSIIFALGKILGRPADVVSEFLYSLTLQNFSKVLNPVGHP..WSTCH.VPLS.NYDTCDYYM...G...IFDSQGNLRNPYHPESLKKLIQVMQSV.LRER.......................................PDAD......NGAHDA.LFGDVIMRR.RRGKNR----...----.-------...AKRAGIGPESA..........AQDRGQRRIQESNERA.QELARNL....NRIG.THCDWHEHRERKPPEYGIPC.F..GTPFGPPNAFGPGAGIltpdrgdpfglkgs....pwgrgglnggafgagRRLSEsfsisfdetlfkgpdgqvlqadqdgsgrgfsrdrrpgssPRGKELSSLIDGVNKKTKLTKDLGTLIDAVTGLDV-----EPKQQKDITKSKH..........................LQRRLSDEYN.....................................................................................................................................................................................................
A0A6P4I371_DROKI/59-201 ..........................hslpp-----RWLEVNRRVIYALAKRMGRSPEAAHYAVLLLLYANYGKVLRIAQKR..R-SFP.VPRC.GFPEQDFFCtggS...LFNDSGFLTDPMAPDTLAKLLRMLQDY.ISRLrelnk............................kfkwyaN---......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------gedrdeilcllgeqdelvrllraifgnk.........................................................................................................................................................................
B3MKM7_DROAN/45-183 ..............................l-SSERRWGQLNSGMIGALAKMVNKSADKVCQFLHHLTLHLFSRILYPLAAG..WNTLK.IPFV.LSDTCELYY...G...IYDEDGNLRNPIPTRTLLVLITMLRYF.LNLP.......................................LVKD......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------kgcrrkkkcqccqdmehdmrnihnpgycgkgamn...................................................................................................................................................................
A0A6I8W0G5_DROPS/70-401 ..............................l-TDKQRWFLINQSIIFALGKILGRPADVVSEFLYSLTLQNFSKVLNPVGHP..WSTCH.VPLS.NYDTCDYYM...G...IFDSQGNLRNPYHPESLKKLIQVMQSV.LRER.......................................PDAD......NGAHDA.LFGDVIMRR.RRGKNR----...----.-------...AKRAGIGPESA..........AQDRGQRRIQESNERA.QEMARNL....NRIG.THCDWHEHRERKPPEYGIPC.F..GTPFGPPNAFGPGAGIltpdrgdpfglkgs....lwgrgglnggafgagRRLSEsfsisfdetlfkgpdgqvlqadqdgsgrgfsrdrrpgssPRGKELSSLIDGVNKKTKLTKDLDTLIDAVTGLDV-----DPKQQKDITKSKH..........................LQRRLSDEYN.....................................................................................................................................................................................................
A0A6P4EGF8_DRORH/45-192 ..............................m-SSERRWGQRNGVMVELLAKMVDKSANTVCQFLHQLTLQLFARILYPLMAG..WNTLK.IPFV.LPDTCELYY...G...IFDECGNLRKPMPTRTFVILITILQYF.LNLP.......................................TQ--......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------rvcrgknkctacknkdnmikhlhnpgycgkdamtpfsgrrtteka........................................................................................................................................................
B4N654_DROWI/64-177 ...........................tlpp-----RWLDINRNVIFELARRLQQSPEATHYMLLRLLHANYGKVMRIMKRR..RS-YD.VPLS.SQALFFSPS...S...LIDENGNLFEPMHPESVEKLLRLIQDY.LHR-.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------mqllnrkykwfnngld.....................................................................................................................................................................................
A0A6P4FZC7_DRORH/61-165 .............................pp-----RWLEVNRRVIYALANHLDRSPEAAHYMLLRLLYANYRKVMVISRKR..-RSFR.VPLS.GFPDQDLFSa.sG...LFDSNGYLYDPMAPETLGKLLRMMQDY.I---.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------frlralnlk............................................................................................................................................................................................
A0A6P4HT12_DROKI/40-178 ..............................l-STKRRWGLMNVGMIQALAKMVNQSTERVGQFLHQLTLQLFARILQPLMAG..WNTRK.IPFT.LPDTCELYY...G...IFDECGNIRCPIPTRTLLILITMMQYF.LNLP.......................................RE--......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------cgrkieglkrrckcgstedslkdihnpgycrnvvlf.................................................................................................................................................................
B4Q4G7_DROSI/70-333 ...............................KSHKERWFLTNQRIILALATTLNRPPDLVSDFLHTLTLQNFSEILHPVETEtlGPSCK.VPFV.NCGACENFM...R...IFDTHGNVRSRLSQDSLQLLMEAVQTV.LQ--.......................................----......------.----QSPPT.ELRALDAGFS...GQRG.AIKRHSI...ARRAGIDRDSI..........ARQNGRRRLRNSEARA.SENRSHL....NTGL.EQRTAGDPGYVFGSSLESAG.L..NA-MHTPEKWAFTDSL.................................AL---.......................................ERTRRLSKLLIQVNEKTYLTRDTEKLITAIKELNLDSNVTNPKKQPPRHSIM-..........................-ANVISDSYY.....................................................................................................................................................................................................
A0A3B0J6K5_DROGU/52-189 ...........................lpgk------WLALNRKLITTMAVRMRRSTQTIHYMLLRLLHANYAGVLQIVRKR..R-AYK.VPISgYPDALFSTF...S...LFNDQGYVSLPMAPESVGKLMRMMQDY.VV--.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------qmqllnrqykwfrngqdqgdlvgllgqqdellkllrgtfrg............................................................................................................................................................
B4IIH2_DROSE/70-411 ...............................KSHKERWFLTNQRIILALATTLNRPPDLVSDFLHTLTLQNFSEILHPVETEtlGPSYR.VPFV.NCGACENFM...R...IFDTHGNLRSRLSQDSLQLLMEAVQTV.LQ--.......................................----......------.----QSPPT.ELCAFDAGFS...GQRG.TIKRHSI...ARRAGIDRDSI..........ARQNGRRRLRNSEARA.SENRSHL....NTGL.EQRTAGDPGYVFGSSLESAG.L..NV-MHTPEKWAFTDSL.................................AL---.......................................ERTRRLSKLLIQPPRHSI-----------------------------------..........................----------manvisdsyyervkasaskqshsargskkrkkasdvepvpkrttnrvyygdplpvllhepfnrekpwtwlrrhpqqmrmdekgqvtqgtirryrrqtveqmmqnakerssvitvistgden............................................................................
B3MHT4_DROAN/67-208 .............................pp-----RWLEMNREAIFAMAAKLNRSPEAAHYLVIQLLHANYGKVMTISRK-..RRTFK.VPLA.GYPDQDFFT...AgntIFNRRGDVIAPLAPETLSKLLLMMQDY.IFRLrllnr............................kykwygNGDD......HGNILC.LLGEQDE--.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------lvrllkdlfggssd.......................................................................................................................................................................................
B4Q7D5_DROSI/35-329 ...............................SQEHCLWRQRNKVEIEQLAKLVGFQPNEIDSFLFNLSLRHYSDLLKPKDCG..WNYCN.VPLC.YPYVCDRYM...A...IFDHRGNLRSPIHERSLKSLLPLLLDY.LNGDspndrkdspiyea.............ypdehpakcrsniEQNHlesmvsSDWISQ.VFGSPSESK.SEKTGKKTNK...PQP-.-------...VMRSELGTELEs.......esQTDKKKGKNKTFGRQS.VFLNDEL....--AL.AYAKSYDYAEYLMKTLGRHR.F..RDSYIGPVGD------.................................-----.......................................LRTTRTRILIRDLIARKGMNINEKNLRKALKKVDLEWKGTTRADYKREMKT--..........................-AQEISRLYN.....................................................................................................................................................................................................
A0A6P4JAR9_DROKI/10-291 ..............................n-TAKERWFFTNQHIILGLAKVLERPPNAVSDFLYLLTLQNFSQIMKPVMPP..GNHCK.VPLV.FPNSCEDYM...R...LFDTQGNIRSRFSHDSLMLLMRVMQAW.LRKG.......................................----......--AHSNiKPFDPCFEG.TQCRQRNGIK...T---.-------...-RKVGIDRDSM..........AHRNGRRRLQESDARA.CLVRSKL....--IG.YSANGCDYSVAQGSSLQGKL.S..SGDPGYVFGTHFSPRDsngwhqddpp.............shlrkldgpeDELAA.......................................ERARRLEALLVQLNERTYLTRDAGALIRAIKDIKVGIPAR----KKVKSAIDN..........................SVKLISDSYY.....................................................................................................................................................................................................
B4Q7D6_DROSI/45-186 ............................vsg---ERRWGQRNGCMIQVLAKMVNKSSSTVCQFLHQLTLQVFARILYPLMLG..WNTLK.VPFV.IPDICELYY...G...IFDECGNLRCSIPTRTLLILISMIQYF.LNLP.......................................KRCG......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------qnntcqgcrsqaddlrnnhspgycgknamtpfsgrei................................................................................................................................................................
B4K090_DROGR/68-402 ..............................s-SLKLRWHRTNRNIIMALARVLDIQSDIVSDFLYTLSLQNFGQVLRPQGRQqlSSRCR.VPLS.DLDICDTYC...S...IFDGSGNLRNPYHPESLLQLLTILQSV.LKAGk....................................elKESA......NAAHGK.LFGQQNTQS.R---------...GER-.------L...AHRAGIGEDSL..........ARQNGRRRRYRLYAN-.-------....----.YRLDGFDTLFDVKKNFAAPF.A..------PNSEDLGYSRnpfiankrsnalaq....dlgaadanlwlskypKELSHvdkfnnrfygnya.............ayskslgdvgqgrRSGIHLRHLIRNVNTKVGIGRDPGDLANAMRKLDLNEVQVNEANAKAMPDA-DrgmspgvrshmqppgkkwkmnshlyhGARTISHQYH.....................................................................................................................................................................................................
A0A6I8VYS1_DROPS/70-401 ..............................l-TDKQRWFLINQSIIFALGKILGRPADVVSEFLYSLTLQNFSKVLNPVGHP..WSTCH.VPLS.NYDTCDYYM...G...IFDSQGNLRNPYHPESLKKLIQVMQSV.LRER.......................................PDAD......NGAHDA.LFGDVIMRR.RRGKNR----...----.-------...AKRAGIGPESA..........AQDRGQRRIQESNERA.QEMARNL....NRIG.THCDWHEHRERKPPEYGIPC.F..GTPFGPPNAFGPGAGIltpdrgdpfglkgs....lwgrgglnggafgagRRLSEsfsisfdetlfkgpdgqvlqadqdgsgrgfsrdrrpgssPRGKELSSLIDGVNKKTKLTKDLDTLIDAVTGLDV-----DPKQQKDITKSKH..........................LQRRLSDEYN.....................................................................................................................................................................................................
A0A6J2U819_DROLE/59-174 ............................atk---LRRWYRRNSSVIRQIAKILEKEPDDVAAFLYGLTMRDFSKMINPMGSG..WNWCR.VPYC.TVDTCDRYW...E...IFDDNGNLRYPHDPRRLFALLDFIQNS.----.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------mcppvgsgtdtllkgaqsy..................................................................................................................................................................................
A0A484B8B4_DRONA/40-185 ..............................n-SEERRWCLHNGSMLRKLAGIVRKPLHQVCSFMFELTMKKFGEITNPKCSR..WTYCR.VPLV.RPDTCALYD...G...IYDRQGNLRPVFHPYILHLVVSILRHY.LNLP.......................................-CAM......EKPPSK.RPEY-----.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------emfasrkgttckdffkprrkrgkrfgkggrgg.....................................................................................................................................................................
A0A484BD06_DRONA/85-410 ..............................a-SPEEYWYGTNRQNLVALSQTLELPVDRVADFLYTLTMQNFSRMLKPRS-T..CFDCR.VPLC.KGDPCTLYA...S...VFDDEGNVRNPFGPGTLVEVLRVLQMV.VREGv....................................dePPNA......KKPTST.RSTRVKQLR.DEKQQIYAQK...PQL-.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------deklqiyapkrllthiyasspldyrnapfatapvepqpssvhlrqlishinrvrgtevdlaqflektdldaalpaqkrfhnltkyevpkvhkklsvhqdgvptekrkqkwadhmylgeqipvlmhkpfnpnerqtylrrhpaslrmnqdgcvvnsknvhryrrrsverllrearkrasihsivtvspdnls......
Q9VJK1_DROME/45-177 ............................vsg---ERRWGQRNGCMIQVLAKMVNKSSSTVCQFLHQLTLQVFARILYPLMLG..WNTLK.VPFV.IPDICELYY...G...IFDECGNIRGSIPTRTLLILISMIQYF.LNLP.......................................K---......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------rcgqnsacsgcrsqtddlrnihspgycgkna......................................................................................................................................................................
A0A0Q9WA38_DROVI/48-320 ..............................i-TDWDLWYGRDIKVFSDLASKLDKPIHKIAELMYDFTLQNYSDILNPRGKG..WNHCR.IPFS.RGDICERYM...S...IFDLEGNLRDPTHPRSLFRLLQVIKSI.ST--.......................................SDIA......DVAESR.PIYNLATIR.IAN-GAHGNA...T---.----NKS...LKNIDLDYMHI..........KKSHELRQF-DMYAK-.PDVHPIL....NQSH.ASNKPIDHPYHIKIETADVR.R..ATISLHDSDLLLVDKKgrrrg......................qgsnqlDSLRL.......................................HQKLI----LHKMLRKNLKDEDPSRFLDALAKTDL--NESHSKHLKRVQA---..........................-AQHISNFY-s....................................................................................................................................................................................................
B4JE18_DROGR/68-402 ..............................s-SLKLRWHRTNRNIIMALARVLDIQADIVSDFLYTLSLQNFGQVLRPQGRQqlSSRCR.VPLS.DLDICDTYC...S...IFDGSGNLRNPYHPESLLQLLTILQSV.LKAGk....................................elKESA......NAAHGK.LFGQESTQS.K---------...GER-.------L...AHRAGIGEDSL..........ARQNGRRRRYRLYAN-.-------....----.YLHDGFDTLFDVKKNFAAPF.A..------PNSEDLGYSRnpfiankrsnalaq....dlgaadanlwlskypKELSHvdkfnnrfygnya.............ayskslgdvgqgrRSGIHLRHLIRNVNAKVGIGHDPSDLANAMGKLDLNEVQVNEANAKAMPDAYRgmspgvrshmlp.pgkkwkmnshlyhGARTISHQYH.....................................................................................................................................................................................................
A0A6J2TQU1_DROLE/47-172 ..............................r-KPHKRWLQINSRLVSNLAERLNCSTKTVHVMLFHLLFTNYLDWVRIVRRR..RS-FQ.LSFV.KNLEADFEC...-...FLDKRGNVTSPLEPFMIGALLLMIQNY.VRHV.......................................R---......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------qlnakykwynngiddgkvlellgpqd...........................................................................................................................................................................
A0A0Q9WA38_DROVI/520-672 ..............................h-SEERRWCLHNGSVLRELATILMKPLHQVCRFIFTLTMRKFGQILNPKCSQ..WNYYR.VPFV.RPDTCALYD...G...IFDVDGNLRNPLHPYIRHLLVTILYYF.LNMP.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------cgeaiqprrksegdifdrrggtcknffdrgsmtagqaaafnqfmaestfgcg.................................................................................................................................................
Q8IP16_DROME/35-329 ...............................SQEHCLWRQRNQMEIEQLAKLVGFQPDEIDGFLFNLSLRNYSDLLKYKECG..WNGCN.VPLC.YPYVCDRYM...A...IFDHRGNLRSPIHARSLKSLLPLLLDY.LNGDspndrkdspiyea.............ypdehqakcrsniEQSDleamssSDWISQ.LLGNPSESK.REKTGKKTEK...PQP-.-------...VMRSELESELEs.......esEMEKKKRKNKTFGRQS.VFLNDEL....--AL.AYAKSYDYAEYLMKTLGRHR.F..RDSYIGPVGD------.................................-----.......................................LRTTRTHILIRDLIARKGMNINEKNLRKALKKVDLEWKGTTRADYKREMKT--..........................-AQEISRLYN.....................................................................................................................................................................................................
B4G7Q7_DROPE/34-156 ..............................s-SPQHQWWNRNCVIVRLLANAVDQSAGNVCTFLYQLTLNLFSRILGPLVMG..WNTLK.VPFA.MSDTFDLYY...G...IFDENGDLRRPMAMKTFVLLLIMMKRF.L---.......................................----......------.---------.----------...----.-------...-----------..........----------------.-------....----.--------------------.-..----------------.................................-----.......................................-----------------------------------------------------..........................----------clpcrmmrprdktghspimfctktm............................................................................................................................................................................
#=GC seq_cons ................................p.pcpWhppNpphIhtLAphlspsscpVspFLapLTLpNauclLpPhtpt..hsth+.VPhs.tsssC-hYh...u...IFDppGNLRsPhpPcoLhtLlphhQsh.Lp.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
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