#=GF ID   DUF4852
#=GF AC   PF16144.9
#=GF DE   Domain of unknown function (DUF4852)
#=GF AU   Chang Y;0000-0002-2418-3433
#=GF SE   Jackhmmer JCSG target SP18734A
#=GF GA   22.80 22.80;
#=GF TC   23.10 22.80;
#=GF NC   22.40 22.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR032325;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several uncharacterized proteins around
#=GF CC   350 residues in length and is mainly found in various
#=GF CC   Parabacteroides, Bacteroides and Porphyromonas species. The
#=GF CC   function of this family  is unknown.
#=GF SQ   25
#=GS A0A261GIN8_9GAMM/80-192   AC A0A261GIN8.1
#=GS U6RL87_9BACT/170-293      AC U6RL87.1
#=GS W4P5D2_9BACE/159-282      AC W4P5D2.1
#=GS A0A3L7ZZT9_9BACT/168-291  AC A0A3L7ZZT9.1
#=GS A0A0S2I558_9BACT/164-292  AC A0A0S2I558.1
#=GS E6VY80_PSEA9/174-298      AC E6VY80.1
#=GS A0A4S4AZM0_9RHOO/78-175   AC A0A4S4AZM0.1
#=GS C8X5U6_DESRD/41-161       AC C8X5U6.1
#=GS A0A059F7W9_9PROT/55-175   AC A0A059F7W9.1
#=GS A0A4R2NBI9_9PAST/50-170   AC A0A4R2NBI9.1
#=GS I1DTB3_9GAMM/90-214       AC I1DTB3.1
#=GS A0A1Y0N512_9BURK/83-193   AC A0A1Y0N512.1
#=GS A0A5S9ITM6_9BACT/47-166   AC A0A5S9ITM6.1
#=GS A0A518GBU9_9BACT/47-168   AC A0A518GBU9.1
#=GS G2KRG7_MICAA/85-217       AC G2KRG7.1
#=GS A0A6N7EXL6_9GAMM/156-274  AC A0A6N7EXL6.1
#=GS A0A062TYE8_9PROT/57-168   AC A0A062TYE8.1
#=GS A0A368USX1_9BACT/161-289  AC A0A368USX1.1
#=GS A0A2V1GRE9_9GAMM/81-193   AC A0A2V1GRE9.1
#=GS A0A059EHB4_9MICR/42-99    AC A0A059EHB4.1
#=GS E4RV40_LEAB4/22-139       AC E4RV40.1
#=GS A0A6M4IR30_9BACT/173-275  AC A0A6M4IR30.1
#=GS A0A2P8QZW3_9PROT/46-167   AC A0A2P8QZW3.1
#=GS F2IE88_FLUTR/164-278      AC F2IE88.1
#=GS A6LIV5_PARD8/159-282      AC A6LIV5.1
A0A261GIN8_9GAMM/80-192              ........edylksriglkavs-------------------LRNNEITYQKEIQRSAGLLAD..DLSRHS.LKPTYQITISSELGKYDVKQHGFPVRHKK-VIELKGN.........--NSMI.......NL.PKRI...............NVNITNYDQLP.M.LSMDLNEAERFL--ga.......
U6RL87_9BACT/170-293                 ....................dt--ASVETYASLCAPQQYAEAANDPFALEELRTTYRKELEQ..AVAKAD.FNKVFRIKCLSELQMYDINQQRFPLSGLTCVNVETKQn......seLSQQGY.......CL.WGTC...............AFHFTNAPSFA.T.LPCEKSIAQGIYT-m........
W4P5D2_9BACE/159-282                 ......................DDKVVDKYASLCVPDEFKQASEDPFALDAMRKSYRAKLQQ..ELCNAD.FSKIFRLKCLSELQPYDMVKECFPLSEFSCVDVQTKQ.........-EDELSrl...kyCL.WGEC...............AFLFANASLFM.S.LPSEKTRAKGFYG-m........
A0A3L7ZZT9_9BACT/168-291             ....................dt--TSVDTYASLRAPQQYAEAANDPFALEELRTTYRKELEQ..AVAKAD.FNKVFRIKCFSKLQMYDINQQHFPLSDLKC-IDVETKqd.....edLSKQGY.......CL.WGTC...............AFHFTNAPSFA.T.VPCDKHIAQGVY--am.......
A0A0S2I558_9BACT/164-292             ....................sk--DIAKEYLYLFHRNKYNSIREDEFEFHQNLKETQKKLTD..LLEMQD.TSKVFIMNFKDEVGNYDFDKEAFPIKWKHN--GEQVYtdlweiltpY-----.......--.--DInkdkv.....kltdlRIQFNNTNQFS.E.LKLNMEKASQFVK-f........
E6VY80_PSEA9/174-298                 ......................DEQAIIDYVKTKDCEAVQRAERDEFALAKLKHDARAEAEA..FLRSAK.PELV-ELTFPARLGEYDFDKSAFPFAPMPT--GTSKKvga..gwslWCPKNT.......TF.PESI...............QVSIKGGEVIQ.H.LAMAPDAAESLLK-s........
A0A4S4AZM0_9RHOO/78-175              ..............aadpafla--------------------TENRFERQELLRSLRPQLEA..QLAQHG.ENRYIVIPMQVQLAAYDFHRRGF---PVHGFAADSYL.........------.......RFgPQDY...............ALSFTNGAEFS.L.VPIADEQ-------lare.....
C8X5U6_DESRD/41-161                  ....................dy-EANVDSYMKIYRSDVWDRYKNDEFEIQDKRNETIKMMKD..RFSSFS.LDEEFTIYTSLKFGSYDFDKQVF---PLNSFSANSYLve.....rrY----Nn.....wSF.PKAY...............KVFFINPEKIG.D.INMEKDKAKNFLKK.........
A0A059F7W9_9PROT/55-175              ....................dy-ESNVDCYMRLYRSEVWQRSREDEFLRQDKRDETIEMMKA..RVGEAN.LEDVYTVRTNKDFGDYDFDTNVFEFAPVSK---TTYFy.......vRNNNSC.......GL.PSEI...............RVKFDNPEIID.G.IAMSRDDAQALLT-s........
A0A4R2NBI9_9PAST/50-170              .................plaee-------WLLYSDKPTYHKYKNDEFEFQDKVEEAGKKLKT..LVEKAP.LSPEFTILVDTQFGEYDFEKNQFTYQPL--MNGHLYIdg.....glITHYTK.......TL.PRRI...............NLYVSNPEVID.G.IQMPKAEAKKFIQ-h........
I1DTB3_9GAMM/90-214                  .....................sYDQNATDLMRIYYPDIYTKYRNDEFELASKRQAAVSKIKQ..TTEEFD.ETRVHQLFTEWDFGTYDFEKSEFPLDSLTTTTSYSFK.........--QDSLrm..psnNF.PREF...............RLYFTNPEVIG.N.LKMDPEAAKVFLQK.........
A0A1Y0N512_9BURK/83-193              ........idyeksaqaisaey------------------RGQSDDFKKRDLLNALKPRIDA..EVAKAK.SAKYFFANFDAELDKYDFESKAFPLKNLRD-SGTYWY.........F-----.......YD.VNAY...............RYSFLNGAVFN.K.IPVVD---------etmarties
A0A5S9ITM6_9BACT/47-166              delfeflsnkqylryryaakki--------------------------YEKKRQKFISKLQK..SIGNWK.-KTNYKITLTGNFGEYNFKKQRFRIQNIIAVGGEQKL.........-SAPILl.....yRS.TNSLk............ipAIVFTNTKKFR.S.FFVPLETAKQLYD-s........
A0A518GBU9_9BACT/47-168              ....................dv-DANVEWYMENYREATWNLARNDEFLMHEKKEETRKIFQN..RIDQFD.VEQTFTLRANMEIGDYDFSNQEFPRDHN----GPDSY.........WYKSSS.......KY.SESIps...........tlKLFMKNYDFLH.G.VPMEPAAARAFIQ-s........
G2KRG7_MICAA/85-217                  ....................ds-DDDIDNYLLINECEMYTKFYHNDFEWQEIRRVTRDYIQK..NITQFP.--QTFEVIMPIYLDRYDIGAEKFLIEPESQFIGVSRLdtr...ynnVSDDICgvkstieNY.PRNL...............VLNFNLPFSLR.D.IPVKPEVAEFYMQ-e........
A0A6N7EXL6_9GAMM/156-274             ..................esev----LEAYLGQYHCPQLKE-ANDEFSRLRLEEEHRAAFEA..DFAQPS.-PKLF-IEFRKKFDKYDIDRGGFPIDLTRSFYVRDHR.........ECRYVNm.....rNF.S-SL...............ELKTLDARLIN.T.IELPISKAEEFYQK.........
A0A062TYE8_9PROT/57-168              ..........anmmtkplnmrf---------------------DNEFERRRFTKENFPAFQK..MAEDVM.AQPAYYTKFSVRLGDYDFTDERFPINGI--YSGSMYFn.......yDADKAG.......SE.GMDY...............AVRIVNTDEIK.F.LDMAPDDAEALLN-r........
A0A368USX1_9BACT/161-289             .....................d-KNTIKEYAYRFDRKGYRENFKDEFSFHSYLAKKEDELKK..ELAGFD.NEKLYVLPVKLEFGSYDFDKNSFPIVWDGN-------.........MMPLLR.......DQ.TENLiagdvnsegidlldlNVFLENKDDFT.S.FKLHPTKAKIL---vdy......
A0A2V1GRE9_9GAMM/81-193              ....................ad-------YLQHQIGLKAHSLKNNEIAYQKAVNRSVRDLGA..ALNQHK.LKTAYQITVSSQIGKYNFANQEFPIRLAKKFKLQ---.........GGSNIA.......TL.PRHI...............TVLVENQDALP.N.LKMDADTAESFLD-g........
A0A059EHB4_9MICR/42-99               ......................DTQDIIQYWKYCHKNEYNKINNESFSLESRKYYLEKNLTK..TISGFI.-TSYF--------------------------------.........------.......--.----...............-----------.-.--------------nlprtkrp.
E4RV40_LEAB4/22-139                  ..................ndsy----YKQYCEIFHTKEFNK-SMNEFDRQEFRAKMQERMRD..GIRAVI.NREQFYYLREARLSEYNFGAQLFSFPGS-ALPYFKYF........fY-----.......--.ASDGgv...........riRLNTVNENKFNfV.LRMTPEKAREYLTK.........
A0A6M4IR30_9BACT/173-275             ...........vtsrnkslqql----------------------PAFDRPDSARVWAQQLDA..RLTTLP.TDATFRVRVNDNVSEYDHAQQRF---SVHFFEPGTYL.........---PLQ.......VF.GEEY...............RVVFSNADAAR.F.INMSKDAARPF---de.......
A0A2P8QZW3_9PROT/46-167              ..................mgew-------YLYNFNSNKYRQVKNDEFEFHDTVQEGYKQFIKlvNLNKDKiKNTEYKTTLKIEFNEYDFKNEGF---PLDLIAENSYIp......fyGSDKPT......cNY.AQS-...............ELSFDNANTSK.NfLPIKKEDASKFVK-s........
F2IE88_FLUTR/164-278                 .....................s-ADNALKYCKIVDPAKGKAFELNLSQFEKEKAEWVKKLDL..ARKGVQ.LKDTFILTLPAYLSKYAFDKGEFQIVDNPTVYGSKAL.........------.......TY.SGDT...............KVVFDNYKSFT.T.LKSAKENADFFLN-v........
A6LIV5_PARD8/159-282                 ......................DDDVIVRYMAHCDKNLVEKNQADPFTMADLKKEYAAKLEK..ALGDVD.FSKVFRIESQSEMLQYDMDKQIFPLKGL---------.........WCPQIK......tDQ.PDALakigf....ckwddcVFRFVNIPEFM.N.VPCETARAKGFYDM.........
#=GC seq_cons                        ....................p.....h.tYh.hht.t.hpphppD-Fphpchcpchtpplcp..plsphs.hppsFplphpsclucYDFcpptFslpshpth.spphh.........h............sh.spsh...............plhFsNssths.s.lshshcpActahp..........
//